FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8411, 866 aa 1>>>pF1KB8411 866 - 866 aa - 866 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.2298+/-0.000902; mu= 5.3560+/- 0.055 mean_var=238.5945+/-48.196, 0's: 0 Z-trim(114.4): 16 B-trim: 0 in 0/54 Lambda= 0.083032 statistics sampled from 14937 (14950) to 14937 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.77), E-opt: 0.2 (0.459), width: 16 Scan time: 4.950 The best scores are: opt bits E(32554) CCDS34595.1 RNF216 gene_id:54476|Hs108|chr7 ( 866) 6077 741.3 1.7e-213 CCDS34594.1 RNF216 gene_id:54476|Hs108|chr7 ( 923) 5614 685.9 8.9e-197 >>CCDS34595.1 RNF216 gene_id:54476|Hs108|chr7 (866 aa) initn: 6077 init1: 6077 opt: 6077 Z-score: 3946.4 bits: 741.3 E(32554): 1.7e-213 Smith-Waterman score: 6077; 100.0% identity (100.0% similar) in 866 aa overlap (1-866:1-866) 10 20 30 40 50 60 pF1KB8 MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPMLVTPAPQQHEEEDLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPMLVTPAPQQHEEEDLD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DDVILTEDDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 DDVILTEDDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VIILEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 VIILEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LNQQPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 LNQQPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 EFEDQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 EFEDQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVAN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 GFIEEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 GFIEEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 SKLTPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 SKLTPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 ETSGKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 ETSGKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 FYEQKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 FYEQKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKEC 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 LIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 LIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 ELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 ELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 TSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 TSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 GAPCQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 GAPCQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB8 VEALPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 VEALPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVN 790 800 810 820 830 840 850 860 pF1KB8 YDFGPIHMPLEHNLPMHFGPQPRHRF :::::::::::::::::::::::::: CCDS34 YDFGPIHMPLEHNLPMHFGPQPRHRF 850 860 >>CCDS34594.1 RNF216 gene_id:54476|Hs108|chr7 (923 aa) initn: 5614 init1: 5614 opt: 5614 Z-score: 3646.3 bits: 685.9 E(32554): 8.9e-197 Smith-Waterman score: 5765; 93.7% identity (93.7% similar) in 898 aa overlap (26-866:26-923) 10 20 30 40 50 60 pF1KB8 MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPMLVTPAPQQHEEEDLD ::::::::::::::::::::::::::::::::::: CCDS34 MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPMLVTPAPQQHEEEDLD 10 20 30 40 50 60 pF1KB8 DDVILTE----------------------------------------------------- ::::::: CCDS34 DDVILTETNKPQRSRPNLIKPAAQWQDLKRLGEERPKKSRAAFESDKSSYFSVCNNPLFD 70 80 90 100 110 120 70 80 90 100 110 120 pF1KB8 ----DDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQKVII :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 SGAQDDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQKVII 130 140 150 160 170 180 130 140 150 160 170 180 pF1KB8 LEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQSLNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 LEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQSLNQ 190 200 210 220 230 240 190 200 210 220 230 240 pF1KB8 QPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLGEFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 QPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLGEFE 250 260 270 280 290 300 250 260 270 280 290 300 pF1KB8 DQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVANGFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 DQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVANGFI 310 320 330 340 350 360 310 320 330 340 350 360 pF1KB8 EEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDYSKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 EEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDYSKL 370 380 390 400 410 420 370 380 390 400 410 420 pF1KB8 TPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSPETS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 TPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSPETS 430 440 450 460 470 480 430 440 450 460 470 480 pF1KB8 GKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQEFYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 GKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQEFYE 490 500 510 520 530 540 490 500 510 520 530 540 pF1KB8 QKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 QKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIR 550 560 570 580 590 600 550 560 570 580 590 600 pF1KB8 YAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYADELV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 YAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYADELV 610 620 630 640 650 660 610 620 630 640 650 660 pF1KB8 RCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 RCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSI 670 680 690 700 710 720 670 680 690 700 710 720 pF1KB8 EEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSPGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 EEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSPGAP 730 740 750 760 770 780 730 740 750 760 770 780 pF1KB8 CQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQRVEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 CQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQRVEA 790 800 810 820 830 840 790 800 810 820 830 840 pF1KB8 LPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVNYDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 LPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVNYDF 850 860 870 880 890 900 850 860 pF1KB8 GPIHMPLEHNLPMHFGPQPRHRF ::::::::::::::::::::::: CCDS34 GPIHMPLEHNLPMHFGPQPRHRF 910 920 866 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:42:52 2016 done: Fri Nov 4 12:42:53 2016 Total Scan time: 4.950 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]