FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8411, 866 aa 1>>>pF1KB8411 866 - 866 aa - 866 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.1244+/-0.000367; mu= 5.9056+/- 0.023 mean_var=264.2513+/-53.004, 0's: 0 Z-trim(121.8): 42 B-trim: 0 in 0/59 Lambda= 0.078898 statistics sampled from 39007 (39055) to 39007 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.771), E-opt: 0.2 (0.458), width: 16 Scan time: 15.440 The best scores are: opt bits E(85289) XP_016867852 (OMIM: 212840,609948) PREDICTED: E3 u ( 866) 6077 705.5 2.7e-202 NP_996999 (OMIM: 212840,609948) E3 ubiquitin-prote ( 866) 6077 705.5 2.7e-202 NP_996994 (OMIM: 212840,609948) E3 ubiquitin-prote ( 923) 5614 652.8 2.1e-186 XP_005249842 (OMIM: 212840,609948) PREDICTED: E3 u ( 923) 5614 652.8 2.1e-186 XP_016867853 (OMIM: 212840,609948) PREDICTED: E3 u ( 720) 4094 479.7 2.1e-134 XP_011513738 (OMIM: 212840,609948) PREDICTED: E3 u ( 488) 3493 411.1 6.2e-114 XP_016867854 (OMIM: 212840,609948) PREDICTED: E3 u ( 488) 3493 411.1 6.2e-114 NP_006453 (OMIM: 610924,615895) ranBP-type and C3H ( 468) 286 46.1 0.00046 NP_112506 (OMIM: 610924,615895) ranBP-type and C3H ( 510) 286 46.1 0.00049 XP_005260702 (OMIM: 610924,615895) PREDICTED: ranB ( 527) 286 46.1 0.0005 XP_011527440 (OMIM: 610924,615895) PREDICTED: ranB ( 551) 286 46.2 0.00052 XP_011527439 (OMIM: 610924,615895) PREDICTED: ranB ( 568) 286 46.2 0.00053 XP_016861030 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 409) 248 41.7 0.0084 XP_016861029 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 409) 248 41.7 0.0084 XP_016861026 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421) 248 41.7 0.0086 XP_011531577 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421) 248 41.7 0.0086 XP_016861027 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421) 248 41.7 0.0086 XP_016861025 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421) 248 41.7 0.0086 XP_016861028 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 421) 248 41.7 0.0086 XP_016861020 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 493) 248 41.8 0.0096 NP_001304262 (OMIM: 605615) E3 ubiquitin-protein l ( 493) 248 41.8 0.0096 NP_006312 (OMIM: 605615) E3 ubiquitin-protein liga ( 493) 248 41.8 0.0096 XP_016861021 (OMIM: 605615) PREDICTED: E3 ubiquiti ( 493) 248 41.8 0.0096 >>XP_016867852 (OMIM: 212840,609948) PREDICTED: E3 ubiqu (866 aa) initn: 6077 init1: 6077 opt: 6077 Z-score: 3752.8 bits: 705.5 E(85289): 2.7e-202 Smith-Waterman score: 6077; 100.0% identity (100.0% similar) in 866 aa overlap (1-866:1-866) 10 20 30 40 50 60 pF1KB8 MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPMLVTPAPQQHEEEDLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPMLVTPAPQQHEEEDLD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DDVILTEDDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DDVILTEDDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VIILEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VIILEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LNQQPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNQQPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 EFEDQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFEDQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVAN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 GFIEEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GFIEEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 SKLTPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKLTPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 ETSGKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETSGKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 FYEQKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FYEQKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKEC 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 LIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 ELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 TSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 GAPCQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GAPCQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB8 VEALPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEALPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVN 790 800 810 820 830 840 850 860 pF1KB8 YDFGPIHMPLEHNLPMHFGPQPRHRF :::::::::::::::::::::::::: XP_016 YDFGPIHMPLEHNLPMHFGPQPRHRF 850 860 >>NP_996999 (OMIM: 212840,609948) E3 ubiquitin-protein l (866 aa) initn: 6077 init1: 6077 opt: 6077 Z-score: 3752.8 bits: 705.5 E(85289): 2.7e-202 Smith-Waterman score: 6077; 100.0% identity (100.0% similar) in 866 aa overlap (1-866:1-866) 10 20 30 40 50 60 pF1KB8 MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPMLVTPAPQQHEEEDLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPMLVTPAPQQHEEEDLD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DDVILTEDDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 DDVILTEDDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VIILEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 VIILEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LNQQPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 LNQQPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 EFEDQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 EFEDQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVAN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 GFIEEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 GFIEEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 SKLTPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 SKLTPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 ETSGKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 ETSGKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 FYEQKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKEC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 FYEQKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKEC 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 LIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 LIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYAD 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 ELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 ELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYR 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 TSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 TSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSP 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 GAPCQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 GAPCQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB8 VEALPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 VEALPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVN 790 800 810 820 830 840 850 860 pF1KB8 YDFGPIHMPLEHNLPMHFGPQPRHRF :::::::::::::::::::::::::: NP_996 YDFGPIHMPLEHNLPMHFGPQPRHRF 850 860 >>NP_996994 (OMIM: 212840,609948) E3 ubiquitin-protein l (923 aa) initn: 5614 init1: 5614 opt: 5614 Z-score: 3467.7 bits: 652.8 E(85289): 2.1e-186 Smith-Waterman score: 5765; 93.7% identity (93.7% similar) in 898 aa overlap (26-866:26-923) 10 20 30 40 50 60 pF1KB8 MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPMLVTPAPQQHEEEDLD ::::::::::::::::::::::::::::::::::: NP_996 MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPMLVTPAPQQHEEEDLD 10 20 30 40 50 60 pF1KB8 DDVILTE----------------------------------------------------- ::::::: NP_996 DDVILTETNKPQRSRPNLIKPAAQWQDLKRLGEERPKKSRAAFESDKSSYFSVCNNPLFD 70 80 90 100 110 120 70 80 90 100 110 120 pF1KB8 ----DDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQKVII :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 SGAQDDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQKVII 130 140 150 160 170 180 130 140 150 160 170 180 pF1KB8 LEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQSLNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 LEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQSLNQ 190 200 210 220 230 240 190 200 210 220 230 240 pF1KB8 QPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLGEFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 QPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLGEFE 250 260 270 280 290 300 250 260 270 280 290 300 pF1KB8 DQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVANGFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 DQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVANGFI 310 320 330 340 350 360 310 320 330 340 350 360 pF1KB8 EEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDYSKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 EEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDYSKL 370 380 390 400 410 420 370 380 390 400 410 420 pF1KB8 TPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSPETS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 TPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSPETS 430 440 450 460 470 480 430 440 450 460 470 480 pF1KB8 GKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQEFYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 GKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQEFYE 490 500 510 520 530 540 490 500 510 520 530 540 pF1KB8 QKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 QKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIR 550 560 570 580 590 600 550 560 570 580 590 600 pF1KB8 YAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYADELV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 YAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYADELV 610 620 630 640 650 660 610 620 630 640 650 660 pF1KB8 RCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 RCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSI 670 680 690 700 710 720 670 680 690 700 710 720 pF1KB8 EEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSPGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 EEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSPGAP 730 740 750 760 770 780 730 740 750 760 770 780 pF1KB8 CQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQRVEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 CQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQRVEA 790 800 810 820 830 840 790 800 810 820 830 840 pF1KB8 LPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVNYDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_996 LPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVNYDF 850 860 870 880 890 900 850 860 pF1KB8 GPIHMPLEHNLPMHFGPQPRHRF ::::::::::::::::::::::: NP_996 GPIHMPLEHNLPMHFGPQPRHRF 910 920 >>XP_005249842 (OMIM: 212840,609948) PREDICTED: E3 ubiqu (923 aa) initn: 5614 init1: 5614 opt: 5614 Z-score: 3467.7 bits: 652.8 E(85289): 2.1e-186 Smith-Waterman score: 5765; 93.7% identity (93.7% similar) in 898 aa overlap (26-866:26-923) 10 20 30 40 50 60 pF1KB8 MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPMLVTPAPQQHEEEDLD ::::::::::::::::::::::::::::::::::: XP_005 MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPMLVTPAPQQHEEEDLD 10 20 30 40 50 60 pF1KB8 DDVILTE----------------------------------------------------- ::::::: XP_005 DDVILTETNKPQRSRPNLIKPAAQWQDLKRLGEERPKKSRAAFESDKSSYFSVCNNPLFD 70 80 90 100 110 120 70 80 90 100 110 120 pF1KB8 ----DDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQKVII :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SGAQDDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQKVII 130 140 150 160 170 180 130 140 150 160 170 180 pF1KB8 LEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQSLNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQSLNQ 190 200 210 220 230 240 190 200 210 220 230 240 pF1KB8 QPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLGEFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLGEFE 250 260 270 280 290 300 250 260 270 280 290 300 pF1KB8 DQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVANGFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVANGFI 310 320 330 340 350 360 310 320 330 340 350 360 pF1KB8 EEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDYSKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDYSKL 370 380 390 400 410 420 370 380 390 400 410 420 pF1KB8 TPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSPETS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSPETS 430 440 450 460 470 480 430 440 450 460 470 480 pF1KB8 GKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQEFYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQEFYE 490 500 510 520 530 540 490 500 510 520 530 540 pF1KB8 QKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIR 550 560 570 580 590 600 550 560 570 580 590 600 pF1KB8 YAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYADELV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYADELV 610 620 630 640 650 660 610 620 630 640 650 660 pF1KB8 RCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSI 670 680 690 700 710 720 670 680 690 700 710 720 pF1KB8 EEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSPGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSPGAP 730 740 750 760 770 780 730 740 750 760 770 780 pF1KB8 CQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQRVEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 CQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQRVEA 790 800 810 820 830 840 790 800 810 820 830 840 pF1KB8 LPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVNYDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVNYDF 850 860 870 880 890 900 850 860 pF1KB8 GPIHMPLEHNLPMHFGPQPRHRF ::::::::::::::::::::::: XP_005 GPIHMPLEHNLPMHFGPQPRHRF 910 920 >>XP_016867853 (OMIM: 212840,609948) PREDICTED: E3 ubiqu (720 aa) initn: 4592 init1: 4092 opt: 4094 Z-score: 2534.0 bits: 479.7 E(85289): 2.1e-134 Smith-Waterman score: 4245; 91.7% identity (91.8% similar) in 695 aa overlap (26-663:26-720) 10 20 30 40 50 60 pF1KB8 MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPMLVTPAPQQHEEEDLD ::::::::::::::::::::::::::::::::::: XP_016 MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPMLVTPAPQQHEEEDLD 10 20 30 40 50 60 pF1KB8 DDVILTE----------------------------------------------------- ::::::: XP_016 DDVILTETNKPQRSRPNLIKPAAQWQDLKRLGEERPKKSRAAFESDKSSYFSVCNNPLFD 70 80 90 100 110 120 70 80 90 100 110 120 pF1KB8 ----DDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQKVII :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGAQDDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQKVII 130 140 150 160 170 180 130 140 150 160 170 180 pF1KB8 LEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQSLNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQSLNQ 190 200 210 220 230 240 190 200 210 220 230 240 pF1KB8 QPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLGEFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLGEFE 250 260 270 280 290 300 250 260 270 280 290 300 pF1KB8 DQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVANGFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVANGFI 310 320 330 340 350 360 310 320 330 340 350 360 pF1KB8 EEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDYSKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDYSKL 370 380 390 400 410 420 370 380 390 400 410 420 pF1KB8 TPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSPETS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSPETS 430 440 450 460 470 480 430 440 450 460 470 480 pF1KB8 GKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQEFYE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQEFYE 490 500 510 520 530 540 490 500 510 520 530 540 pF1KB8 QKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIR 550 560 570 580 590 600 550 560 570 580 590 600 pF1KB8 YAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYADELV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYADELV 610 620 630 640 650 660 610 620 630 640 650 660 pF1KB8 RCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. XP_016 RCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSM 670 680 690 700 710 720 670 680 690 700 710 720 pF1KB8 EEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSPGAP >>XP_011513738 (OMIM: 212840,609948) PREDICTED: E3 ubiqu (488 aa) initn: 3493 init1: 3493 opt: 3493 Z-score: 2166.5 bits: 411.1 E(85289): 6.2e-114 Smith-Waterman score: 3493; 100.0% identity (100.0% similar) in 488 aa overlap (379-866:1-488) 350 360 370 380 390 400 pF1KB8 ETKLPKIDFFDYSKLTPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKAL :::::::::::::::::::::::::::::: XP_011 MADFKVLSSQDIKWALHELKGHYAITRKAL 10 20 30 410 420 430 440 450 460 pF1KB8 SDAIKKWQELSPETSGKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDAIKKWQELSPETSGKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDR 40 50 60 70 80 90 470 480 490 500 510 520 pF1KB8 RALLPAVQQEQEFYEQKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RALLPAVQQEQEFYEQKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELT 100 110 120 130 140 150 530 540 550 560 570 580 pF1KB8 QCADAHLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QCADAHLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYER 160 170 180 190 200 210 590 600 610 620 630 640 pF1KB8 KAEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KAEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTC 220 230 240 250 260 270 650 660 670 680 690 700 pF1KB8 EELAEKDDIKYRTSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EELAEKDDIKYRTSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSIN 280 290 300 310 320 330 710 720 730 740 750 760 pF1KB8 GYDHFCQHPRSPGAPCQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GYDHFCQHPRSPGAPCQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIG 340 350 360 370 380 390 770 780 790 800 810 820 pF1KB8 PPLEKPVEKVQRVEALPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPLEKPVEKVQRVEALPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPA 400 410 420 430 440 450 830 840 850 860 pF1KB8 PYVPPLPNVRVNYDFGPIHMPLEHNLPMHFGPQPRHRF :::::::::::::::::::::::::::::::::::::: XP_011 PYVPPLPNVRVNYDFGPIHMPLEHNLPMHFGPQPRHRF 460 470 480 >>XP_016867854 (OMIM: 212840,609948) PREDICTED: E3 ubiqu (488 aa) initn: 3493 init1: 3493 opt: 3493 Z-score: 2166.5 bits: 411.1 E(85289): 6.2e-114 Smith-Waterman score: 3493; 100.0% identity (100.0% similar) in 488 aa overlap (379-866:1-488) 350 360 370 380 390 400 pF1KB8 ETKLPKIDFFDYSKLTPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKAL :::::::::::::::::::::::::::::: XP_016 MADFKVLSSQDIKWALHELKGHYAITRKAL 10 20 30 410 420 430 440 450 460 pF1KB8 SDAIKKWQELSPETSGKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDAIKKWQELSPETSGKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDR 40 50 60 70 80 90 470 480 490 500 510 520 pF1KB8 RALLPAVQQEQEFYEQKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RALLPAVQQEQEFYEQKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELT 100 110 120 130 140 150 530 540 550 560 570 580 pF1KB8 QCADAHLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QCADAHLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYER 160 170 180 190 200 210 590 600 610 620 630 640 pF1KB8 KAEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KAEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTC 220 230 240 250 260 270 650 660 670 680 690 700 pF1KB8 EELAEKDDIKYRTSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EELAEKDDIKYRTSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSIN 280 290 300 310 320 330 710 720 730 740 750 760 pF1KB8 GYDHFCQHPRSPGAPCQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GYDHFCQHPRSPGAPCQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIG 340 350 360 370 380 390 770 780 790 800 810 820 pF1KB8 PPLEKPVEKVQRVEALPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPLEKPVEKVQRVEALPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPA 400 410 420 430 440 450 830 840 850 860 pF1KB8 PYVPPLPNVRVNYDFGPIHMPLEHNLPMHFGPQPRHRF :::::::::::::::::::::::::::::::::::::: XP_016 PYVPPLPNVRVNYDFGPIHMPLEHNLPMHFGPQPRHRF 460 470 480 >>NP_006453 (OMIM: 610924,615895) ranBP-type and C3HC4-t (468 aa) initn: 87 init1: 87 opt: 286 Z-score: 193.9 bits: 46.1 E(85289): 0.00046 Smith-Waterman score: 290; 25.0% identity (53.7% similar) in 296 aa overlap (467-730:193-467) 440 450 460 470 480 490 pF1KB8 YIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQEFYEQKIKEMAEHEDFL ..:: : . .. . :.:. :.. .. ..: NP_006 INKPTRPGCEMCCRARPEAYQVPASYQPDEEERARLAGEEEALRQYQQR-KQQQQEGNYL 170 180 190 200 210 220 500 510 520 530 540 550 pF1KB8 LALQMNEEQYQKDGQLIECRCCYGEF-PFEE--LTQCADAHLFCKECL---IRYAQEAVF .:..... . . :: ::. . : : : .: : ::.::: :: .::: NP_006 QHVQLDQRSLVLNTEPAECPVCYSVLAPGEAVVLREC--LHTFCRECLQGTIRNSQEA-- 230 240 250 260 270 560 570 580 590 600 pF1KB8 GSGKLELSC--MEGSCTCSFPTSELEKVLPQTILYKYYER-------KAEEEVAAAYADE :.:: .... .:: . ::. . . . :.: ::.. : .: NP_006 -----EVSCPFIDNTYSCS--GKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYH-- 280 290 300 310 320 610 620 630 640 650 pF1KB8 LVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAE------KD . :.:. ....::..:.:: : . .: :... :. ..:.: : .. NP_006 -CKTPDCKGWCFFEDDVNEFTCPV--CFHVNCLLCKAI---HEQMNCKEYQEDLALRAQN 330 340 350 360 370 380 660 670 680 690 700 pF1KB8 DIKYRTSIEE---KMTAARIRKCHKCGTGLIKSEGCNRMSCR-CGAQMCYLC---RVSIN :. : . : . .. .: .: . :..::. . : : ...:.. : . . NP_006 DVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPRWGPG 390 400 410 420 430 440 710 720 730 740 750 760 pF1KB8 GYDHF---CQHPRSPGAPCQE-CSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTF : :. : : ::. :. : NP_006 GPGDTSGGCRC-RVNGIPCHPSCQNCH 450 460 >>NP_112506 (OMIM: 610924,615895) ranBP-type and C3HC4-t (510 aa) initn: 87 init1: 87 opt: 286 Z-score: 193.4 bits: 46.1 E(85289): 0.00049 Smith-Waterman score: 290; 25.0% identity (53.7% similar) in 296 aa overlap (467-730:235-509) 440 450 460 470 480 490 pF1KB8 YIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQEFYEQKIKEMAEHEDFL ..:: : . .. . :.:. :.. .. ..: NP_112 INKPTRPGCEMCCRARPEAYQVPASYQPDEEERARLAGEEEALRQYQQR-KQQQQEGNYL 210 220 230 240 250 260 500 510 520 530 540 550 pF1KB8 LALQMNEEQYQKDGQLIECRCCYGEF-PFEE--LTQCADAHLFCKECL---IRYAQEAVF .:..... . . :: ::. . : : : .: : ::.::: :: .::: NP_112 QHVQLDQRSLVLNTEPAECPVCYSVLAPGEAVVLREC--LHTFCRECLQGTIRNSQEA-- 270 280 290 300 310 560 570 580 590 600 pF1KB8 GSGKLELSC--MEGSCTCSFPTSELEKVLPQTILYKYYER-------KAEEEVAAAYADE :.:: .... .:: . ::. . . . :.: ::.. : .: NP_112 -----EVSCPFIDNTYSCS--GKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYH-- 320 330 340 350 360 370 610 620 630 640 650 pF1KB8 LVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAE------KD . :.:. ....::..:.:: : . .: :... :. ..:.: : .. NP_112 -CKTPDCKGWCFFEDDVNEFTCPV--CFHVNCLLCKAI---HEQMNCKEYQEDLALRAQN 380 390 400 410 420 660 670 680 690 700 pF1KB8 DIKYRTSIEE---KMTAARIRKCHKCGTGLIKSEGCNRMSCR-CGAQMCYLC---RVSIN :. : . : . .. .: .: . :..::. . : : ...:.. : . . NP_112 DVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPRWGPG 430 440 450 460 470 480 710 720 730 740 750 760 pF1KB8 GYDHF---CQHPRSPGAPCQE-CSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTF : :. : : ::. :. : NP_112 GPGDTSGGCRC-RVNGIPCHPSCQNCH 490 500 510 >>XP_005260702 (OMIM: 610924,615895) PREDICTED: ranBP-ty (527 aa) initn: 87 init1: 87 opt: 286 Z-score: 193.2 bits: 46.1 E(85289): 0.0005 Smith-Waterman score: 290; 25.0% identity (53.7% similar) in 296 aa overlap (467-730:252-526) 440 450 460 470 480 490 pF1KB8 YIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQEFYEQKIKEMAEHEDFL ..:: : . .. . :.:. :.. .. ..: XP_005 INKPTRPGCEMCCRARPEAYQVPASYQPDEEERARLAGEEEALRQYQQR-KQQQQEGNYL 230 240 250 260 270 280 500 510 520 530 540 550 pF1KB8 LALQMNEEQYQKDGQLIECRCCYGEF-PFEE--LTQCADAHLFCKECL---IRYAQEAVF .:..... . . :: ::. . : : : .: : ::.::: :: .::: XP_005 QHVQLDQRSLVLNTEPAECPVCYSVLAPGEAVVLREC--LHTFCRECLQGTIRNSQEA-- 290 300 310 320 330 560 570 580 590 600 pF1KB8 GSGKLELSC--MEGSCTCSFPTSELEKVLPQTILYKYYER-------KAEEEVAAAYADE :.:: .... .:: . ::. . . . :.: ::.. : .: XP_005 -----EVSCPFIDNTYSCS--GKLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYH-- 340 350 360 370 380 610 620 630 640 650 pF1KB8 LVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAE------KD . :.:. ....::..:.:: : . .: :... :. ..:.: : .. XP_005 -CKTPDCKGWCFFEDDVNEFTCPV--CFHVNCLLCKAI---HEQMNCKEYQEDLALRAQN 390 400 410 420 430 440 660 670 680 690 700 pF1KB8 DIKYRTSIEE---KMTAARIRKCHKCGTGLIKSEGCNRMSCR-CGAQMCYLC---RVSIN :. : . : . .. .: .: . :..::. . : : ...:.. : . . XP_005 DVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCDWIRCTVCHTEICWVTKGPRWGPG 450 460 470 480 490 500 710 720 730 740 750 760 pF1KB8 GYDHF---CQHPRSPGAPCQE-CSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTF : :. : : ::. :. : XP_005 GPGDTSGGCRC-RVNGIPCHPSCQNCH 510 520 866 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:42:53 2016 done: Fri Nov 4 12:42:55 2016 Total Scan time: 15.440 Total Display time: 0.230 Function used was FASTA [36.3.4 Apr, 2011]