FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8413, 720 aa 1>>>pF1KB8413 720 - 720 aa - 720 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8993+/-0.000413; mu= 17.3406+/- 0.026 mean_var=81.0133+/-15.920, 0's: 0 Z-trim(112.2): 43 B-trim: 58 in 2/51 Lambda= 0.142494 statistics sampled from 21058 (21093) to 21058 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.613), E-opt: 0.2 (0.247), width: 16 Scan time: 10.160 The best scores are: opt bits E(85289) NP_573403 (OMIM: 606421,606893) engulfment and cel ( 720) 4714 979.4 0 XP_006723917 (OMIM: 606421,606893) PREDICTED: engu ( 720) 4714 979.4 0 NP_877496 (OMIM: 606421,606893) engulfment and cel ( 720) 4714 979.4 0 XP_005260553 (OMIM: 606421,606893) PREDICTED: engu ( 720) 4714 979.4 0 XP_005260557 (OMIM: 606421,606893) PREDICTED: engu ( 632) 4123 857.8 0 XP_005260556 (OMIM: 606421,606893) PREDICTED: engu ( 632) 4123 857.8 0 XP_005260555 (OMIM: 606421,606893) PREDICTED: engu ( 632) 4123 857.8 0 NP_001305182 (OMIM: 606421,606893) engulfment and ( 632) 4123 857.8 0 XP_006715868 (OMIM: 606420) PREDICTED: engulfment ( 727) 3705 771.9 0 NP_055615 (OMIM: 606420) engulfment and cell motil ( 727) 3705 771.9 0 NP_001193409 (OMIM: 606420) engulfment and cell mo ( 727) 3705 771.9 0 XP_011513956 (OMIM: 606420) PREDICTED: engulfment ( 727) 3705 771.9 0 NP_001193411 (OMIM: 606420) engulfment and cell mo ( 727) 3705 771.9 0 XP_016868327 (OMIM: 606420) PREDICTED: engulfment ( 727) 3705 771.9 0 XP_016868328 (OMIM: 606420) PREDICTED: engulfment ( 727) 3705 771.9 0 XP_005249976 (OMIM: 606420) PREDICTED: engulfment ( 727) 3705 771.9 0 XP_016883499 (OMIM: 606421,606893) PREDICTED: engu ( 537) 3534 736.7 5.5e-212 XP_016883500 (OMIM: 606421,606893) PREDICTED: engu ( 537) 3534 736.7 5.5e-212 XP_005260558 (OMIM: 606421,606893) PREDICTED: engu ( 537) 3534 736.7 5.5e-212 XP_016883498 (OMIM: 606421,606893) PREDICTED: engu ( 537) 3534 736.7 5.5e-212 NP_078988 (OMIM: 606422) engulfment and cell motil ( 773) 2454 514.8 5.1e-145 NP_001034548 (OMIM: 606420) engulfment and cell mo ( 247) 1336 284.7 3e-76 NP_569709 (OMIM: 606420) engulfment and cell motil ( 247) 1336 284.7 3e-76 >>NP_573403 (OMIM: 606421,606893) engulfment and cell mo (720 aa) initn: 4714 init1: 4714 opt: 4714 Z-score: 5235.9 bits: 979.4 E(85289): 0 Smith-Waterman score: 4714; 100.0% identity (100.0% similar) in 720 aa overlap (1-720:1-720) 10 20 30 40 50 60 pF1KB8 MPPPSDIVKVAIEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_573 MPPPSDIVKVAIEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ITEQTRSDIKNGTILQLAISPSRAARQLMERTQSSNMETRLDAMKELAKLSADVTFATEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_573 ITEQTRSDIKNGTILQLAISPSRAARQLMERTQSSNMETRLDAMKELAKLSADVTFATEF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 INMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAGYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_573 INMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAGYV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIALIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_573 SQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIALIN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 ALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_573 ALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEER 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 MMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKMLGFTNHINP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_573 MMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKMLGFTNHINP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 AMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_573 AMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 LQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_573 LQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 ITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_573 ITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILEL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 IKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEVTFESLQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_573 IKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEVTFESLQEK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 IPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_573 IPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWID 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 GLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFVYHYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_573 GLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFVYHYG 670 680 690 700 710 720 >>XP_006723917 (OMIM: 606421,606893) PREDICTED: engulfme (720 aa) initn: 4714 init1: 4714 opt: 4714 Z-score: 5235.9 bits: 979.4 E(85289): 0 Smith-Waterman score: 4714; 100.0% identity (100.0% similar) in 720 aa overlap (1-720:1-720) 10 20 30 40 50 60 pF1KB8 MPPPSDIVKVAIEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MPPPSDIVKVAIEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ITEQTRSDIKNGTILQLAISPSRAARQLMERTQSSNMETRLDAMKELAKLSADVTFATEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ITEQTRSDIKNGTILQLAISPSRAARQLMERTQSSNMETRLDAMKELAKLSADVTFATEF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 INMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAGYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 INMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAGYV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIALIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIALIN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 ALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEER 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 MMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKMLGFTNHINP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKMLGFTNHINP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 AMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 LQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 ITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILEL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 IKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEVTFESLQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEVTFESLQEK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 IPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWID 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 GLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFVYHYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFVYHYG 670 680 690 700 710 720 >>NP_877496 (OMIM: 606421,606893) engulfment and cell mo (720 aa) initn: 4714 init1: 4714 opt: 4714 Z-score: 5235.9 bits: 979.4 E(85289): 0 Smith-Waterman score: 4714; 100.0% identity (100.0% similar) in 720 aa overlap (1-720:1-720) 10 20 30 40 50 60 pF1KB8 MPPPSDIVKVAIEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 MPPPSDIVKVAIEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ITEQTRSDIKNGTILQLAISPSRAARQLMERTQSSNMETRLDAMKELAKLSADVTFATEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 ITEQTRSDIKNGTILQLAISPSRAARQLMERTQSSNMETRLDAMKELAKLSADVTFATEF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 INMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAGYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 INMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAGYV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIALIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 SQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIALIN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 ALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 ALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEER 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 MMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKMLGFTNHINP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 MMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKMLGFTNHINP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 AMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 AMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 LQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 LQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 ITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 ITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILEL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 IKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEVTFESLQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 IKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEVTFESLQEK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 IPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 IPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWID 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 GLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFVYHYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_877 GLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFVYHYG 670 680 690 700 710 720 >>XP_005260553 (OMIM: 606421,606893) PREDICTED: engulfme (720 aa) initn: 4714 init1: 4714 opt: 4714 Z-score: 5235.9 bits: 979.4 E(85289): 0 Smith-Waterman score: 4714; 100.0% identity (100.0% similar) in 720 aa overlap (1-720:1-720) 10 20 30 40 50 60 pF1KB8 MPPPSDIVKVAIEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MPPPSDIVKVAIEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ITEQTRSDIKNGTILQLAISPSRAARQLMERTQSSNMETRLDAMKELAKLSADVTFATEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ITEQTRSDIKNGTILQLAISPSRAARQLMERTQSSNMETRLDAMKELAKLSADVTFATEF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 INMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAGYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 INMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAGYV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIALIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIALIN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 ALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEER 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 MMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKMLGFTNHINP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKMLGFTNHINP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 AMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 LQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 ITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILEL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 IKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEVTFESLQEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEVTFESLQEK 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 IPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWID 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 GLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFVYHYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFVYHYG 670 680 690 700 710 720 >>XP_005260557 (OMIM: 606421,606893) PREDICTED: engulfme (632 aa) initn: 4123 init1: 4123 opt: 4123 Z-score: 4580.1 bits: 857.8 E(85289): 0 Smith-Waterman score: 4123; 100.0% identity (100.0% similar) in 632 aa overlap (89-720:1-632) 60 70 80 90 100 110 pF1KB8 LYITEQTRSDIKNGTILQLAISPSRAARQLMERTQSSNMETRLDAMKELAKLSADVTFAT :::::::::::::::::::::::::::::: XP_005 MERTQSSNMETRLDAMKELAKLSADVTFAT 10 20 30 120 130 140 150 160 170 pF1KB8 EFINMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EFINMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAG 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB8 YVSQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YVSQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIAL 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB8 INALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 INALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLE 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB8 ERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKMLGFTNHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKMLGFTNHI 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB8 NPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLC 280 290 300 310 320 330 420 430 440 450 460 470 pF1KB8 EILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVR 340 350 360 370 380 390 480 490 500 510 520 530 pF1KB8 EQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEIL 400 410 420 430 440 450 540 550 560 570 580 590 pF1KB8 ELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEVTFESLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEVTFESLQ 460 470 480 490 500 510 600 610 620 630 640 650 pF1KB8 EKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIW 520 530 540 550 560 570 660 670 680 690 700 710 pF1KB8 IDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFVYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFVYH 580 590 600 610 620 630 720 pF1KB8 YG :: XP_005 YG >>XP_005260556 (OMIM: 606421,606893) PREDICTED: engulfme (632 aa) initn: 4123 init1: 4123 opt: 4123 Z-score: 4580.1 bits: 857.8 E(85289): 0 Smith-Waterman score: 4123; 100.0% identity (100.0% similar) in 632 aa overlap (89-720:1-632) 60 70 80 90 100 110 pF1KB8 LYITEQTRSDIKNGTILQLAISPSRAARQLMERTQSSNMETRLDAMKELAKLSADVTFAT :::::::::::::::::::::::::::::: XP_005 MERTQSSNMETRLDAMKELAKLSADVTFAT 10 20 30 120 130 140 150 160 170 pF1KB8 EFINMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EFINMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAG 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB8 YVSQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YVSQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIAL 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB8 INALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 INALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLE 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB8 ERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKMLGFTNHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKMLGFTNHI 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB8 NPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLC 280 290 300 310 320 330 420 430 440 450 460 470 pF1KB8 EILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVR 340 350 360 370 380 390 480 490 500 510 520 530 pF1KB8 EQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEIL 400 410 420 430 440 450 540 550 560 570 580 590 pF1KB8 ELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEVTFESLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEVTFESLQ 460 470 480 490 500 510 600 610 620 630 640 650 pF1KB8 EKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIW 520 530 540 550 560 570 660 670 680 690 700 710 pF1KB8 IDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFVYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFVYH 580 590 600 610 620 630 720 pF1KB8 YG :: XP_005 YG >>XP_005260555 (OMIM: 606421,606893) PREDICTED: engulfme (632 aa) initn: 4123 init1: 4123 opt: 4123 Z-score: 4580.1 bits: 857.8 E(85289): 0 Smith-Waterman score: 4123; 100.0% identity (100.0% similar) in 632 aa overlap (89-720:1-632) 60 70 80 90 100 110 pF1KB8 LYITEQTRSDIKNGTILQLAISPSRAARQLMERTQSSNMETRLDAMKELAKLSADVTFAT :::::::::::::::::::::::::::::: XP_005 MERTQSSNMETRLDAMKELAKLSADVTFAT 10 20 30 120 130 140 150 160 170 pF1KB8 EFINMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EFINMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAG 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB8 YVSQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YVSQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIAL 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB8 INALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 INALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLE 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB8 ERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKMLGFTNHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKMLGFTNHI 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB8 NPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLC 280 290 300 310 320 330 420 430 440 450 460 470 pF1KB8 EILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVR 340 350 360 370 380 390 480 490 500 510 520 530 pF1KB8 EQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEIL 400 410 420 430 440 450 540 550 560 570 580 590 pF1KB8 ELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEVTFESLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEVTFESLQ 460 470 480 490 500 510 600 610 620 630 640 650 pF1KB8 EKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIW 520 530 540 550 560 570 660 670 680 690 700 710 pF1KB8 IDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFVYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFVYH 580 590 600 610 620 630 720 pF1KB8 YG :: XP_005 YG >>NP_001305182 (OMIM: 606421,606893) engulfment and cell (632 aa) initn: 4123 init1: 4123 opt: 4123 Z-score: 4580.1 bits: 857.8 E(85289): 0 Smith-Waterman score: 4123; 100.0% identity (100.0% similar) in 632 aa overlap (89-720:1-632) 60 70 80 90 100 110 pF1KB8 LYITEQTRSDIKNGTILQLAISPSRAARQLMERTQSSNMETRLDAMKELAKLSADVTFAT :::::::::::::::::::::::::::::: NP_001 MERTQSSNMETRLDAMKELAKLSADVTFAT 10 20 30 120 130 140 150 160 170 pF1KB8 EFINMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EFINMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAG 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB8 YVSQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YVSQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIAL 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB8 INALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 INALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLE 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB8 ERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKMLGFTNHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKMLGFTNHI 220 230 240 250 260 270 360 370 380 390 400 410 pF1KB8 NPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLC 280 290 300 310 320 330 420 430 440 450 460 470 pF1KB8 EILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVR 340 350 360 370 380 390 480 490 500 510 520 530 pF1KB8 EQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEIL 400 410 420 430 440 450 540 550 560 570 580 590 pF1KB8 ELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEVTFESLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEVTFESLQ 460 470 480 490 500 510 600 610 620 630 640 650 pF1KB8 EKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIW 520 530 540 550 560 570 660 670 680 690 700 710 pF1KB8 IDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFVYH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFVYH 580 590 600 610 620 630 720 pF1KB8 YG :: NP_001 YG >>XP_006715868 (OMIM: 606420) PREDICTED: engulfment and (727 aa) initn: 2768 init1: 2157 opt: 3705 Z-score: 4114.8 bits: 771.9 E(85289): 0 Smith-Waterman score: 3705; 75.7% identity (92.8% similar) in 725 aa overlap (1-717:1-724) 10 20 30 40 50 60 pF1KB8 MPPPSDIVKVAIEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLY ::::.:::::::::::: .:.:::::.::..::::::::::: : ::..:..::. ..: XP_006 MPPPADIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ITEQTRSDIKNGTILQLAISPSRAARQLMERTQSSNMETRLDAMKELAKLSADVTFATEF :::..:..:::::::.:. ::.. :.:: :: :::.:...:.:.:.::.:: ::::: :: XP_006 ITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEF 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 INMDGIIVLTRLVESGT-------KLLSH-YSEMLAFTLTAFLELMDHGIVSWDMVSITF ::.::: .::..::::: :... ...::.::::::.::::::::::: :..: XP_006 INLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAF 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 IKQIAGYVSQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQ ::.::..:.. .:.:::::::::::::::::..::::.:.:::.:::: ::: :.:::: XP_006 IKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGSDQEIQ 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB8 TYAIALINALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVL ::.::.:::::::::...::.::: .:::.::::::.::::..: :..:::::::::::: XP_006 TYTIAVINALFLKAPDERRQEMANILAQKQLRSIILTHVIRAQRAINNEMAHQLYVLQVL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB8 TFNLLEERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKML ::::::.::::::::.::::::::::::::::::::.:.:. :: ::::.:::.::: : XP_006 TFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGS-MEKRKSMYTRDYKKL 310 320 330 340 350 360 370 380 390 400 410 pF1KB8 GFTNHINPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIE :: ::.:::::::::::::::::::::.:: :::.::::::::::::::::::::::.:: XP_006 GFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIE 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB8 LTKMLCEILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNK :::::::::.:::::.: ::.:::::::::.:::.: ::::::::::::::::.::::: XP_006 LTKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNK 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB8 VMQVVREQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREK :::::.::. ::: .::.:::::::::..:::.:::..::::::.:.:::: ::.::.:: XP_006 VMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEK 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB8 IQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEV ::::::::::::::::: ::. :::.. ::::..::::::. ::::::::::...::::: XP_006 IQPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEV 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB8 TFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNK .:::.:.:::::::.::::::::::::.:::::::::::::::::: . ::::::.: XP_006 PHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDK 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB8 YEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSS .::::: :::.::::::: :.::..:::::::::.:::::::::::::.::::::::::. XP_006 HEYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSN 660 670 680 690 700 710 720 pF1KB8 YDFVYHYG ::::: XP_006 YDFVYDCN 720 >>NP_055615 (OMIM: 606420) engulfment and cell motility (727 aa) initn: 2768 init1: 2157 opt: 3705 Z-score: 4114.8 bits: 771.9 E(85289): 0 Smith-Waterman score: 3705; 75.7% identity (92.8% similar) in 725 aa overlap (1-717:1-724) 10 20 30 40 50 60 pF1KB8 MPPPSDIVKVAIEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLY ::::.:::::::::::: .:.:::::.::..::::::::::: : ::..:..::. ..: NP_055 MPPPADIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ITEQTRSDIKNGTILQLAISPSRAARQLMERTQSSNMETRLDAMKELAKLSADVTFATEF :::..:..:::::::.:. ::.. :.:: :: :::.:...:.:.:.::.:: ::::: :: NP_055 ITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEF 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 INMDGIIVLTRLVESGT-------KLLSH-YSEMLAFTLTAFLELMDHGIVSWDMVSITF ::.::: .::..::::: :... ...::.::::::.::::::::::: :..: NP_055 INLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAF 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 IKQIAGYVSQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQ ::.::..:.. .:.:::::::::::::::::..::::.:.:::.:::: ::: :.:::: NP_055 IKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGSDQEIQ 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB8 TYAIALINALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVL ::.::.:::::::::...::.::: .:::.::::::.::::..: :..:::::::::::: NP_055 TYTIAVINALFLKAPDERRQEMANILAQKQLRSIILTHVIRAQRAINNEMAHQLYVLQVL 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB8 TFNLLEERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKML ::::::.::::::::.::::::::::::::::::::.:.:. :: ::::.:::.::: : NP_055 TFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGS-MEKRKSMYTRDYKKL 310 320 330 340 350 360 370 380 390 400 410 pF1KB8 GFTNHINPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIE :: ::.:::::::::::::::::::::.:: :::.::::::::::::::::::::::.:: NP_055 GFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIE 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB8 LTKMLCEILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNK :::::::::.:::::.: ::.:::::::::.:::.: ::::::::::::::::.::::: NP_055 LTKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNK 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB8 VMQVVREQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREK :::::.::. ::: .::.:::::::::..:::.:::..::::::.:.:::: ::.::.:: NP_055 VMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEK 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB8 IQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEV ::::::::::::::::: ::. :::.. ::::..::::::. ::::::::::...::::: NP_055 IQPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEV 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB8 TFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNK .:::.:.:::::::.::::::::::::.:::::::::::::::::: . ::::::.: NP_055 PHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDK 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB8 YEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSS .::::: :::.::::::: :.::..:::::::::.:::::::::::::.::::::::::. NP_055 HEYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSN 660 670 680 690 700 710 720 pF1KB8 YDFVYHYG ::::: NP_055 YDFVYDCN 720 720 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:44:05 2016 done: Fri Nov 4 12:44:07 2016 Total Scan time: 10.160 Total Display time: 0.170 Function used was FASTA [36.3.4 Apr, 2011]