FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8417, 785 aa 1>>>pF1KB8417 785 - 785 aa - 785 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4001+/-0.000405; mu= 14.6341+/- 0.025 mean_var=86.1801+/-17.513, 0's: 0 Z-trim(112.9): 30 B-trim: 63 in 1/53 Lambda= 0.138156 statistics sampled from 21909 (21939) to 21909 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.607), E-opt: 0.2 (0.257), width: 16 Scan time: 12.760 The best scores are: opt bits E(85289) XP_005250566 (OMIM: 616785) PREDICTED: putative ho ( 751) 4879 983.1 0 NP_001120829 (OMIM: 616785) putative homeodomain t ( 751) 4879 983.1 0 XP_005250565 (OMIM: 616785) PREDICTED: putative ho ( 751) 4879 983.1 0 NP_065165 (OMIM: 616785) putative homeodomain tran ( 747) 4837 974.7 0 NP_001120830 (OMIM: 616785) putative homeodomain t ( 747) 4837 974.7 0 XP_011514726 (OMIM: 616785) PREDICTED: putative ho ( 610) 4023 812.4 0 XP_011514724 (OMIM: 616785) PREDICTED: putative ho ( 707) 3575 723.1 9.7e-208 XP_016867947 (OMIM: 616785) PREDICTED: putative ho ( 703) 3533 714.8 3.2e-205 XP_006716126 (OMIM: 616785) PREDICTED: putative ho ( 708) 2712 551.1 5.9e-156 XP_016867948 (OMIM: 616785) PREDICTED: putative ho ( 674) 2198 448.7 3.9e-125 XP_011514725 (OMIM: 616785) PREDICTED: putative ho ( 678) 2198 448.7 3.9e-125 NP_001120831 (OMIM: 616785) putative homeodomain t ( 356) 2176 444.2 4.6e-124 NP_001120832 (OMIM: 616785) putative homeodomain t ( 352) 2134 435.8 1.5e-121 NP_001309975 (OMIM: 604950) putative homeodomain t ( 476) 1779 365.1 3.9e-100 NP_001309973 (OMIM: 604950) putative homeodomain t ( 720) 1779 365.2 5.7e-100 NP_001309974 (OMIM: 604950) putative homeodomain t ( 720) 1779 365.2 5.7e-100 NP_001309971 (OMIM: 604950) putative homeodomain t ( 762) 1779 365.2 6e-100 NP_001309972 (OMIM: 604950) putative homeodomain t ( 762) 1779 365.2 6e-100 NP_006599 (OMIM: 604950) putative homeodomain tran ( 762) 1779 365.2 6e-100 NP_001309970 (OMIM: 604950) putative homeodomain t ( 762) 1779 365.2 6e-100 NP_001309979 (OMIM: 604950) putative homeodomain t ( 595) 1101 230.0 2.3e-59 NP_001309977 (OMIM: 604950) putative homeodomain t ( 637) 1101 230.0 2.4e-59 NP_001309978 (OMIM: 604950) putative homeodomain t ( 637) 1101 230.0 2.4e-59 NP_001309976 (OMIM: 604950) putative homeodomain t ( 637) 1101 230.0 2.4e-59 NP_001309980 (OMIM: 604950) putative homeodomain t ( 533) 678 145.7 5e-34 NP_001309981 (OMIM: 604950) putative homeodomain t ( 575) 678 145.7 5.4e-34 NP_001309982 (OMIM: 604950) putative homeodomain t ( 575) 678 145.7 5.4e-34 >>XP_005250566 (OMIM: 616785) PREDICTED: putative homeod (751 aa) initn: 4952 init1: 4874 opt: 4879 Z-score: 5254.8 bits: 983.1 E(85289): 0 Smith-Waterman score: 4888; 95.4% identity (95.4% similar) in 785 aa overlap (1-785:1-751) 10 20 30 40 50 60 pF1KB8 MAPKVTDAIVWYQKKEFLSVATTAPGPQQVLPGYCQCSLKDQGLFIQCLIGAYDQQIWEK :: :::::::::::: ::::::::::: XP_005 MASKVTDAIVWYQKK----------------------------------IGAYDQQIWEK 10 20 70 80 90 100 110 120 pF1KB8 SVEQREIKFIKLGLRNKPKKTAHVKPDLIDVDLVRGSAFAKAKPESPWTSLTRKGIVRVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SVEQREIKFIKLGLRNKPKKTAHVKPDLIDVDLVRGSAFAKAKPESPWTSLTRKGIVRVV 30 40 50 60 70 80 130 140 150 160 170 180 pF1KB8 FFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCSTSSPHSIPLTEVIGPIWLMLLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCSTSSPHSIPLTEVIGPIWLMLLLG 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB8 TVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREGDGSSTTDNTQEGAVQNHGTSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREGDGSSTTDNTQEGAVQNHGTSTS 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB8 HSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQC 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB8 ETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRN 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB8 RKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETEDVLWEDLLHCAECHSSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETEDVLWEDLLHCAECHSSC 330 340 350 360 370 380 430 440 450 460 470 480 pF1KB8 TSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPGLEKISAIVWEGNDCKKADMSVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPGLEKISAIVWEGNDCKKADMSVL 390 400 410 420 430 440 490 500 510 520 530 540 pF1KB8 EISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFRLSQATDLEQLTAHSASELYVTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_005 EISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFRLSQATDLEQLTAHSASELYVIA 450 460 470 480 490 500 550 560 570 580 590 600 pF1KB8 FGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTYKQRLLFAKLFGHLTSARRARKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTYKQRLLFAKLFGHLTSARRARKS 510 520 530 540 550 560 610 620 630 640 650 660 pF1KB8 EVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSSAFLLTISVVFICCAQLLHVHEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSSAFLLTISVVFICCAQLLHVHEI 570 580 590 600 610 620 670 680 690 700 710 720 pF1KB8 FLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNTSILLTEQINLYLKMEKKPNKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNTSILLTEQINLYLKMEKKPNKKE 630 640 650 660 670 680 730 740 750 760 770 780 pF1KB8 ELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNITQVVILSAVSGVISDLLGFNLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNITQVVILSAVSGVISDLLGFNLKL 690 700 710 720 730 740 pF1KB8 WKIKS ::::: XP_005 WKIKS 750 >>NP_001120829 (OMIM: 616785) putative homeodomain trans (751 aa) initn: 4952 init1: 4874 opt: 4879 Z-score: 5254.8 bits: 983.1 E(85289): 0 Smith-Waterman score: 4888; 95.4% identity (95.4% similar) in 785 aa overlap (1-785:1-751) 10 20 30 40 50 60 pF1KB8 MAPKVTDAIVWYQKKEFLSVATTAPGPQQVLPGYCQCSLKDQGLFIQCLIGAYDQQIWEK :: :::::::::::: ::::::::::: NP_001 MASKVTDAIVWYQKK----------------------------------IGAYDQQIWEK 10 20 70 80 90 100 110 120 pF1KB8 SVEQREIKFIKLGLRNKPKKTAHVKPDLIDVDLVRGSAFAKAKPESPWTSLTRKGIVRVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVEQREIKFIKLGLRNKPKKTAHVKPDLIDVDLVRGSAFAKAKPESPWTSLTRKGIVRVV 30 40 50 60 70 80 130 140 150 160 170 180 pF1KB8 FFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCSTSSPHSIPLTEVIGPIWLMLLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCSTSSPHSIPLTEVIGPIWLMLLLG 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB8 TVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREGDGSSTTDNTQEGAVQNHGTSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREGDGSSTTDNTQEGAVQNHGTSTS 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB8 HSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQC 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB8 ETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRN 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB8 RKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETEDVLWEDLLHCAECHSSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETEDVLWEDLLHCAECHSSC 330 340 350 360 370 380 430 440 450 460 470 480 pF1KB8 TSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPGLEKISAIVWEGNDCKKADMSVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPGLEKISAIVWEGNDCKKADMSVL 390 400 410 420 430 440 490 500 510 520 530 540 pF1KB8 EISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFRLSQATDLEQLTAHSASELYVTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : NP_001 EISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFRLSQATDLEQLTAHSASELYVIA 450 460 470 480 490 500 550 560 570 580 590 600 pF1KB8 FGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTYKQRLLFAKLFGHLTSARRARKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTYKQRLLFAKLFGHLTSARRARKS 510 520 530 540 550 560 610 620 630 640 650 660 pF1KB8 EVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSSAFLLTISVVFICCAQLLHVHEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSSAFLLTISVVFICCAQLLHVHEI 570 580 590 600 610 620 670 680 690 700 710 720 pF1KB8 FLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNTSILLTEQINLYLKMEKKPNKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNTSILLTEQINLYLKMEKKPNKKE 630 640 650 660 670 680 730 740 750 760 770 780 pF1KB8 ELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNITQVVILSAVSGVISDLLGFNLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNITQVVILSAVSGVISDLLGFNLKL 690 700 710 720 730 740 pF1KB8 WKIKS ::::: NP_001 WKIKS 750 >>XP_005250565 (OMIM: 616785) PREDICTED: putative homeod (751 aa) initn: 4952 init1: 4874 opt: 4879 Z-score: 5254.8 bits: 983.1 E(85289): 0 Smith-Waterman score: 4888; 95.4% identity (95.4% similar) in 785 aa overlap (1-785:1-751) 10 20 30 40 50 60 pF1KB8 MAPKVTDAIVWYQKKEFLSVATTAPGPQQVLPGYCQCSLKDQGLFIQCLIGAYDQQIWEK :: :::::::::::: ::::::::::: XP_005 MASKVTDAIVWYQKK----------------------------------IGAYDQQIWEK 10 20 70 80 90 100 110 120 pF1KB8 SVEQREIKFIKLGLRNKPKKTAHVKPDLIDVDLVRGSAFAKAKPESPWTSLTRKGIVRVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SVEQREIKFIKLGLRNKPKKTAHVKPDLIDVDLVRGSAFAKAKPESPWTSLTRKGIVRVV 30 40 50 60 70 80 130 140 150 160 170 180 pF1KB8 FFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCSTSSPHSIPLTEVIGPIWLMLLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCSTSSPHSIPLTEVIGPIWLMLLLG 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB8 TVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREGDGSSTTDNTQEGAVQNHGTSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREGDGSSTTDNTQEGAVQNHGTSTS 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB8 HSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQC 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB8 ETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRN 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB8 RKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETEDVLWEDLLHCAECHSSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETEDVLWEDLLHCAECHSSC 330 340 350 360 370 380 430 440 450 460 470 480 pF1KB8 TSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPGLEKISAIVWEGNDCKKADMSVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPGLEKISAIVWEGNDCKKADMSVL 390 400 410 420 430 440 490 500 510 520 530 540 pF1KB8 EISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFRLSQATDLEQLTAHSASELYVTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_005 EISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFRLSQATDLEQLTAHSASELYVIA 450 460 470 480 490 500 550 560 570 580 590 600 pF1KB8 FGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTYKQRLLFAKLFGHLTSARRARKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTYKQRLLFAKLFGHLTSARRARKS 510 520 530 540 550 560 610 620 630 640 650 660 pF1KB8 EVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSSAFLLTISVVFICCAQLLHVHEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSSAFLLTISVVFICCAQLLHVHEI 570 580 590 600 610 620 670 680 690 700 710 720 pF1KB8 FLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNTSILLTEQINLYLKMEKKPNKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNTSILLTEQINLYLKMEKKPNKKE 630 640 650 660 670 680 730 740 750 760 770 780 pF1KB8 ELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNITQVVILSAVSGVISDLLGFNLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNITQVVILSAVSGVISDLLGFNLKL 690 700 710 720 730 740 pF1KB8 WKIKS ::::: XP_005 WKIKS 750 >>NP_065165 (OMIM: 616785) putative homeodomain transcri (747 aa) initn: 4801 init1: 4723 opt: 4837 Z-score: 5209.6 bits: 974.7 E(85289): 0 Smith-Waterman score: 4846; 94.9% identity (94.9% similar) in 785 aa overlap (1-785:1-747) 10 20 30 40 50 60 pF1KB8 MAPKVTDAIVWYQKKEFLSVATTAPGPQQVLPGYCQCSLKDQGLFIQCLIGAYDQQIWEK :: :::::::::::: ::::::::::: NP_065 MASKVTDAIVWYQKK----------------------------------IGAYDQQIWEK 10 20 70 80 90 100 110 120 pF1KB8 SVEQREIKFIKLGLRNKPKKTAHVKPDLIDVDLVRGSAFAKAKPESPWTSLTRKGIVRVV :::::::: :::::::::::::::::::::::::::::::::::::::::::::::: NP_065 SVEQREIK----GLRNKPKKTAHVKPDLIDVDLVRGSAFAKAKPESPWTSLTRKGIVRVV 30 40 50 60 70 80 130 140 150 160 170 180 pF1KB8 FFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCSTSSPHSIPLTEVIGPIWLMLLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 FFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCSTSSPHSIPLTEVIGPIWLMLLLG 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB8 TVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREGDGSSTTDNTQEGAVQNHGTSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 TVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREGDGSSTTDNTQEGAVQNHGTSTS 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB8 HSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 HSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQC 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB8 ETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 ETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRN 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB8 RKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETEDVLWEDLLHCAECHSSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 RKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETEDVLWEDLLHCAECHSSC 330 340 350 360 370 380 430 440 450 460 470 480 pF1KB8 TSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPGLEKISAIVWEGNDCKKADMSVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 TSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPGLEKISAIVWEGNDCKKADMSVL 390 400 410 420 430 440 490 500 510 520 530 540 pF1KB8 EISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFRLSQATDLEQLTAHSASELYVTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : NP_065 EISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFRLSQATDLEQLTAHSASELYVIA 450 460 470 480 490 500 550 560 570 580 590 600 pF1KB8 FGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTYKQRLLFAKLFGHLTSARRARKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 FGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTYKQRLLFAKLFGHLTSARRARKS 510 520 530 540 550 560 610 620 630 640 650 660 pF1KB8 EVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSSAFLLTISVVFICCAQLLHVHEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 EVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSSAFLLTISVVFICCAQLLHVHEI 570 580 590 600 610 620 670 680 690 700 710 720 pF1KB8 FLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNTSILLTEQINLYLKMEKKPNKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 FLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNTSILLTEQINLYLKMEKKPNKKE 630 640 650 660 670 680 730 740 750 760 770 780 pF1KB8 ELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNITQVVILSAVSGVISDLLGFNLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 ELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNITQVVILSAVSGVISDLLGFNLKL 690 700 710 720 730 740 pF1KB8 WKIKS ::::: NP_065 WKIKS >>NP_001120830 (OMIM: 616785) putative homeodomain trans (747 aa) initn: 4801 init1: 4723 opt: 4837 Z-score: 5209.6 bits: 974.7 E(85289): 0 Smith-Waterman score: 4846; 94.9% identity (94.9% similar) in 785 aa overlap (1-785:1-747) 10 20 30 40 50 60 pF1KB8 MAPKVTDAIVWYQKKEFLSVATTAPGPQQVLPGYCQCSLKDQGLFIQCLIGAYDQQIWEK :: :::::::::::: ::::::::::: NP_001 MASKVTDAIVWYQKK----------------------------------IGAYDQQIWEK 10 20 70 80 90 100 110 120 pF1KB8 SVEQREIKFIKLGLRNKPKKTAHVKPDLIDVDLVRGSAFAKAKPESPWTSLTRKGIVRVV :::::::: :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVEQREIK----GLRNKPKKTAHVKPDLIDVDLVRGSAFAKAKPESPWTSLTRKGIVRVV 30 40 50 60 70 80 130 140 150 160 170 180 pF1KB8 FFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCSTSSPHSIPLTEVIGPIWLMLLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCSTSSPHSIPLTEVIGPIWLMLLLG 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB8 TVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREGDGSSTTDNTQEGAVQNHGTSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREGDGSSTTDNTQEGAVQNHGTSTS 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB8 HSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQC 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB8 ETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRN 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB8 RKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETEDVLWEDLLHCAECHSSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETEDVLWEDLLHCAECHSSC 330 340 350 360 370 380 430 440 450 460 470 480 pF1KB8 TSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPGLEKISAIVWEGNDCKKADMSVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPGLEKISAIVWEGNDCKKADMSVL 390 400 410 420 430 440 490 500 510 520 530 540 pF1KB8 EISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFRLSQATDLEQLTAHSASELYVTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : NP_001 EISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFRLSQATDLEQLTAHSASELYVIA 450 460 470 480 490 500 550 560 570 580 590 600 pF1KB8 FGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTYKQRLLFAKLFGHLTSARRARKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTYKQRLLFAKLFGHLTSARRARKS 510 520 530 540 550 560 610 620 630 640 650 660 pF1KB8 EVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSSAFLLTISVVFICCAQLLHVHEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSSAFLLTISVVFICCAQLLHVHEI 570 580 590 600 610 620 670 680 690 700 710 720 pF1KB8 FLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNTSILLTEQINLYLKMEKKPNKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNTSILLTEQINLYLKMEKKPNKKE 630 640 650 660 670 680 730 740 750 760 770 780 pF1KB8 ELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNITQVVILSAVSGVISDLLGFNLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNITQVVILSAVSGVISDLLGFNLKL 690 700 710 720 730 740 pF1KB8 WKIKS ::::: NP_001 WKIKS >>XP_011514726 (OMIM: 616785) PREDICTED: putative homeod (610 aa) initn: 4023 init1: 4023 opt: 4023 Z-score: 4334.2 bits: 812.4 E(85289): 0 Smith-Waterman score: 4023; 99.8% identity (99.8% similar) in 610 aa overlap (176-785:1-610) 150 160 170 180 190 200 pF1KB8 LLQVAAIVLFCSTSSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRK :::::::::::::::::::::::::::::: XP_011 MLLLGTVHCQIVSTRTPKPPLSTGGKRRRK 10 20 30 210 220 230 240 250 260 pF1KB8 LRKAAHLEVHREGDGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LRKAAHLEVHREGDGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKN 40 50 60 70 80 90 270 280 290 300 310 320 pF1KB8 SIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQR 100 110 120 130 140 150 330 340 350 360 370 380 pF1KB8 TITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSR 160 170 180 190 200 210 390 400 410 420 430 440 pF1KB8 CSSSRQDSESARPESETEDVLWEDLLHCAECHSSCTSETDVENHQINPCVKKEYRDDPFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CSSSRQDSESARPESETEDVLWEDLLHCAECHSSCTSETDVENHQINPCVKKEYRDDPFH 220 230 240 250 260 270 450 460 470 480 490 500 pF1KB8 QSHLPWLHSSHPGLEKISAIVWEGNDCKKADMSVLEISGMIMNRVNSHIPGIGYQIFGNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSHLPWLHSSHPGLEKISAIVWEGNDCKKADMSVLEISGMIMNRVNSHIPGIGYQIFGNA 280 290 300 310 320 330 510 520 530 540 550 560 pF1KB8 VSLILGLTPFVFRLSQATDLEQLTAHSASELYVTAFGSNEDVIVLSMVIISFVVRVSLVW ::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::: XP_011 VSLILGLTPFVFRLSQATDLEQLTAHSASELYVIAFGSNEDVIVLSMVIISFVVRVSLVW 340 350 360 370 380 390 570 580 590 600 610 620 pF1KB8 IFFFLLCVAERTYKQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IFFFLLCVAERTYKQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKR 400 410 420 430 440 450 630 640 650 660 670 680 pF1KB8 RGPQRSVDVIVSSAFLLTISVVFICCAQLLHVHEIFLDCHYNWELVIWCISLTLFLLRFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RGPQRSVDVIVSSAFLLTISVVFICCAQLLHVHEIFLDCHYNWELVIWCISLTLFLLRFV 460 470 480 490 500 510 690 700 710 720 730 740 pF1KB8 TLGSETSKKYSNTSILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLGSETSKKYSNTSILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRL 520 530 540 550 560 570 750 760 770 780 pF1KB8 YGLTMNPLLYNITQVVILSAVSGVISDLLGFNLKLWKIKS :::::::::::::::::::::::::::::::::::::::: XP_011 YGLTMNPLLYNITQVVILSAVSGVISDLLGFNLKLWKIKS 580 590 600 610 >>XP_011514724 (OMIM: 616785) PREDICTED: putative homeod (707 aa) initn: 3648 init1: 3570 opt: 3575 Z-score: 3850.6 bits: 723.1 E(85289): 9.7e-208 Smith-Waterman score: 4505; 89.8% identity (89.8% similar) in 785 aa overlap (1-785:1-707) 10 20 30 40 50 60 pF1KB8 MAPKVTDAIVWYQKKEFLSVATTAPGPQQVLPGYCQCSLKDQGLFIQCLIGAYDQQIWEK :: :::::::::::: ::::::::::: XP_011 MASKVTDAIVWYQKK----------------------------------IGAYDQQIWEK 10 20 70 80 90 100 110 120 pF1KB8 SVEQREIKFIKLGLRNKPKKTAHVKPDLIDVDLVRGSAFAKAKPESPWTSLTRKGIVRVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVEQREIKFIKLGLRNKPKKTAHVKPDLIDVDLVRGSAFAKAKPESPWTSLTRKGIVRVV 30 40 50 60 70 80 130 140 150 160 170 180 pF1KB8 FFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCSTSSPHSIPLTEVIGPIWLMLLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCSTSSPHSIPLTEVIGPIWLMLLLG 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB8 TVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREGDGSSTTDNTQEGAVQNHGTSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREGDGSSTTDNTQEGAVQNHGTSTS 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB8 HSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQC 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB8 ETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRN 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB8 RKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETEDVLWEDLLHCAECHSSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETEDVLWEDLLHCAECHSSC 330 340 350 360 370 380 430 440 450 460 470 480 pF1KB8 TSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPGLEKISAIVWEGNDCKKADMSVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPGLEKISAIVWEGNDCKKADMSVL 390 400 410 420 430 440 490 500 510 520 530 540 pF1KB8 EISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFRLSQATDLEQLTAHSASELYVTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_011 EISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFRLSQATDLEQLTAHSASELYVIA 450 460 470 480 490 500 550 560 570 580 590 600 pF1KB8 FGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTYKQRLLFAKLFGHLTSARRARKS ::::::::::::::::::::::::::::::::::::::::: XP_011 FGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTYKQR------------------- 510 520 530 540 610 620 630 640 650 660 pF1KB8 EVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSSAFLLTISVVFICCAQLLHVHEI ::::::::::::::::::::::::::::::::::: XP_011 -------------------------RGPQRSVDVIVSSAFLLTISVVFICCAQLLHVHEI 550 560 570 580 670 680 690 700 710 720 pF1KB8 FLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNTSILLTEQINLYLKMEKKPNKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNTSILLTEQINLYLKMEKKPNKKE 590 600 610 620 630 640 730 740 750 760 770 780 pF1KB8 ELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNITQVVILSAVSGVISDLLGFNLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNITQVVILSAVSGVISDLLGFNLKL 650 660 670 680 690 700 pF1KB8 WKIKS ::::: XP_011 WKIKS >>XP_016867947 (OMIM: 616785) PREDICTED: putative homeod (703 aa) initn: 3497 init1: 3419 opt: 3533 Z-score: 3805.4 bits: 714.8 E(85289): 3.2e-205 Smith-Waterman score: 4463; 89.3% identity (89.3% similar) in 785 aa overlap (1-785:1-703) 10 20 30 40 50 60 pF1KB8 MAPKVTDAIVWYQKKEFLSVATTAPGPQQVLPGYCQCSLKDQGLFIQCLIGAYDQQIWEK :: :::::::::::: ::::::::::: XP_016 MASKVTDAIVWYQKK----------------------------------IGAYDQQIWEK 10 20 70 80 90 100 110 120 pF1KB8 SVEQREIKFIKLGLRNKPKKTAHVKPDLIDVDLVRGSAFAKAKPESPWTSLTRKGIVRVV :::::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVEQREIK----GLRNKPKKTAHVKPDLIDVDLVRGSAFAKAKPESPWTSLTRKGIVRVV 30 40 50 60 70 80 130 140 150 160 170 180 pF1KB8 FFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCSTSSPHSIPLTEVIGPIWLMLLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCSTSSPHSIPLTEVIGPIWLMLLLG 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB8 TVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREGDGSSTTDNTQEGAVQNHGTSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREGDGSSTTDNTQEGAVQNHGTSTS 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB8 HSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQC 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB8 ETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRN 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB8 RKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETEDVLWEDLLHCAECHSSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETEDVLWEDLLHCAECHSSC 330 340 350 360 370 380 430 440 450 460 470 480 pF1KB8 TSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPGLEKISAIVWEGNDCKKADMSVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPGLEKISAIVWEGNDCKKADMSVL 390 400 410 420 430 440 490 500 510 520 530 540 pF1KB8 EISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFRLSQATDLEQLTAHSASELYVTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_016 EISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFRLSQATDLEQLTAHSASELYVIA 450 460 470 480 490 500 550 560 570 580 590 600 pF1KB8 FGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTYKQRLLFAKLFGHLTSARRARKS ::::::::::::::::::::::::::::::::::::::::: XP_016 FGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTYKQR------------------- 510 520 530 540 610 620 630 640 650 660 pF1KB8 EVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSSAFLLTISVVFICCAQLLHVHEI ::::::::::::::::::::::::::::::::::: XP_016 -------------------------RGPQRSVDVIVSSAFLLTISVVFICCAQLLHVHEI 550 560 570 670 680 690 700 710 720 pF1KB8 FLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNTSILLTEQINLYLKMEKKPNKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNTSILLTEQINLYLKMEKKPNKKE 580 590 600 610 620 630 730 740 750 760 770 780 pF1KB8 ELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNITQVVILSAVSGVISDLLGFNLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNITQVVILSAVSGVISDLLGFNLKL 640 650 660 670 680 690 pF1KB8 WKIKS ::::: XP_016 WKIKS 700 >>XP_006716126 (OMIM: 616785) PREDICTED: putative homeod (708 aa) initn: 2772 init1: 2694 opt: 2712 Z-score: 2920.9 bits: 551.1 E(85289): 5.9e-156 Smith-Waterman score: 4491; 89.9% identity (89.9% similar) in 785 aa overlap (1-785:1-708) 10 20 30 40 50 60 pF1KB8 MAPKVTDAIVWYQKKEFLSVATTAPGPQQVLPGYCQCSLKDQGLFIQCLIGAYDQQIWEK :: :::::::::::: ::::::::::: XP_006 MASKVTDAIVWYQKK----------------------------------IGAYDQQIWEK 10 20 70 80 90 100 110 120 pF1KB8 SVEQREIKFIKLGLRNKPKKTAHVKPDLIDVDLVRGSAFAKAKPESPWTSLTRKGIVRVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SVEQREIKFIKLGLRNKPKKTAHVKPDLIDVDLVRGSAFAKAKPESPWTSLTRKGIVRVV 30 40 50 60 70 80 130 140 150 160 170 180 pF1KB8 FFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCSTSSPHSIPLTEVIGPIWLMLLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCSTSSPHSIPLTEVIGPIWLMLLLG 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB8 TVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREGDGSSTTDNTQEGAVQNHGTSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREGDGSSTTDNTQEGAVQNHGTSTS 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB8 HSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQC 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB8 ETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRN 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB8 RKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETEDVLWEDLLHCAECHSSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETEDVLWEDLLHCAECHSSC 330 340 350 360 370 380 430 440 450 460 470 480 pF1KB8 TSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPGLEKISAIVWEGNDCKKADMSVL :::::::::::::::::::::::::: XP_006 TSETDVENHQINPCVKKEYRDDPFHQ---------------------------------- 390 400 410 490 500 510 520 530 540 pF1KB8 EISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFRLSQATDLEQLTAHSASELYVTA ::::::::::::::::::::::::::::::::::::::::::::::::: : XP_006 ---------VNSHIPGIGYQIFGNAVSLILGLTPFVFRLSQATDLEQLTAHSASELYVIA 420 430 440 450 460 550 560 570 580 590 600 pF1KB8 FGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTYKQRLLFAKLFGHLTSARRARKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTYKQRLLFAKLFGHLTSARRARKS 470 480 490 500 510 520 610 620 630 640 650 660 pF1KB8 EVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSSAFLLTISVVFICCAQLLHVHEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSSAFLLTISVVFICCAQLLHVHEI 530 540 550 560 570 580 670 680 690 700 710 720 pF1KB8 FLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNTSILLTEQINLYLKMEKKPNKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNTSILLTEQINLYLKMEKKPNKKE 590 600 610 620 630 640 730 740 750 760 770 780 pF1KB8 ELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNITQVVILSAVSGVISDLLGFNLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNITQVVILSAVSGVISDLLGFNLKL 650 660 670 680 690 700 pF1KB8 WKIKS ::::: XP_006 WKIKS >>XP_016867948 (OMIM: 616785) PREDICTED: putative homeod (674 aa) initn: 2375 init1: 2183 opt: 2198 Z-score: 2367.6 bits: 448.7 E(85289): 3.9e-125 Smith-Waterman score: 4167; 85.6% identity (85.6% similar) in 785 aa overlap (1-785:1-674) 10 20 30 40 50 60 pF1KB8 MAPKVTDAIVWYQKKEFLSVATTAPGPQQVLPGYCQCSLKDQGLFIQCLIGAYDQQIWEK :: :::::::::::: ::::::::::: XP_016 MASKVTDAIVWYQKK----------------------------------IGAYDQQIWEK 10 20 70 80 90 100 110 120 pF1KB8 SVEQREIKFIKLGLRNKPKKTAHVKPDLIDVDLVRGSAFAKAKPESPWTSLTRKGIVRVV :::::::: :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SVEQREIK----GLRNKPKKTAHVKPDLIDVDLVRGSAFAKAKPESPWTSLTRKGIVRVV 30 40 50 60 70 80 130 140 150 160 170 180 pF1KB8 FFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCSTSSPHSIPLTEVIGPIWLMLLLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCSTSSPHSIPLTEVIGPIWLMLLLG 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB8 TVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREGDGSSTTDNTQEGAVQNHGTSTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREGDGSSTTDNTQEGAVQNHGTSTS 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB8 HSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQC 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB8 ETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRN 270 280 290 300 310 320 370 380 390 400 410 420 pF1KB8 RKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETEDVLWEDLLHCAECHSSC ::::::::::::: XP_016 RKSHHYKKHYPNE----------------------------------------------- 330 430 440 450 460 470 480 pF1KB8 TSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPGLEKISAIVWEGNDCKKADMSVL :::::::::::::::::::::::::::::::::: XP_016 --------------------------SHLPWLHSSHPGLEKISAIVWEGNDCKKADMSVL 340 350 360 490 500 510 520 530 540 pF1KB8 EISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFRLSQATDLEQLTAHSASELYVTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_016 EISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFRLSQATDLEQLTAHSASELYVIA 370 380 390 400 410 420 550 560 570 580 590 600 pF1KB8 FGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTYKQRLLFAKLFGHLTSARRARKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTYKQRLLFAKLFGHLTSARRARKS 430 440 450 460 470 480 610 620 630 640 650 660 pF1KB8 EVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSSAFLLTISVVFICCAQLLHVHEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSSAFLLTISVVFICCAQLLHVHEI 490 500 510 520 530 540 670 680 690 700 710 720 pF1KB8 FLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNTSILLTEQINLYLKMEKKPNKKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNTSILLTEQINLYLKMEKKPNKKE 550 560 570 580 590 600 730 740 750 760 770 780 pF1KB8 ELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNITQVVILSAVSGVISDLLGFNLKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNITQVVILSAVSGVISDLLGFNLKL 610 620 630 640 650 660 pF1KB8 WKIKS ::::: XP_016 WKIKS 670 785 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 01:31:20 2016 done: Sat Nov 5 01:31:22 2016 Total Scan time: 12.760 Total Display time: 0.260 Function used was FASTA [36.3.4 Apr, 2011]