FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8434, 138 aa 1>>>pF1KB8434 138 - 138 aa - 138 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8148+/-0.000738; mu= 8.5649+/- 0.044 mean_var=90.2588+/-18.818, 0's: 0 Z-trim(110.6): 133 B-trim: 243 in 2/49 Lambda= 0.134999 statistics sampled from 11556 (11738) to 11556 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.739), E-opt: 0.2 (0.361), width: 16 Scan time: 1.720 The best scores are: opt bits E(32554) CCDS6512.1 CDKN2B gene_id:1030|Hs108|chr9 ( 138) 905 185.5 8.7e-48 CCDS6510.1 CDKN2A gene_id:1029|Hs108|chr9 ( 156) 682 142.1 1.1e-34 CCDS56565.1 CDKN2A gene_id:1029|Hs108|chr9 ( 167) 682 142.2 1.2e-34 CCDS6513.1 CDKN2B gene_id:1030|Hs108|chr9 ( 78) 344 76.1 4.3e-15 CCDS12244.1 CDKN2D gene_id:1032|Hs108|chr19 ( 166) 333 74.2 3.5e-14 CCDS555.1 CDKN2C gene_id:1031|Hs108|chr1 ( 168) 289 65.6 1.3e-11 >>CCDS6512.1 CDKN2B gene_id:1030|Hs108|chr9 (138 aa) initn: 905 init1: 905 opt: 905 Z-score: 971.4 bits: 185.5 E(32554): 8.7e-48 Smith-Waterman score: 905; 99.3% identity (99.3% similar) in 138 aa overlap (1-138:1-138) 10 20 30 40 50 60 pF1KB8 MREENKGMPSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVMMMDSAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::: CCDS65 MREENKGMPSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVMMMGSAR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 VAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 VAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLA 70 80 90 100 110 120 130 pF1KB8 EERGHRDVAGYLRTATGD :::::::::::::::::: CCDS65 EERGHRDVAGYLRTATGD 130 >>CCDS6510.1 CDKN2A gene_id:1029|Hs108|chr9 (156 aa) initn: 737 init1: 676 opt: 682 Z-score: 735.9 bits: 142.1 E(32554): 1.1e-34 Smith-Waterman score: 682; 82.0% identity (88.7% similar) in 133 aa overlap (9-137:3-135) 10 20 30 40 50 pF1KB8 MREENKGMPSGGGSDEG----LASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVMMM :..:.: : ::.::::: ::.:: :::::: ::. : .::: :::::: CCDS65 MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 DSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLP ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 GSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLP 60 70 80 90 100 110 120 130 pF1KB8 VDLAEERGHRDVAGYLRTATGD :::::: :::::: :::.:.: CCDS65 VDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSDIPD 120 130 140 150 >>CCDS56565.1 CDKN2A gene_id:1029|Hs108|chr9 (167 aa) initn: 737 init1: 676 opt: 682 Z-score: 735.5 bits: 142.2 E(32554): 1.2e-34 Smith-Waterman score: 682; 82.0% identity (88.7% similar) in 133 aa overlap (9-137:3-135) 10 20 30 40 50 pF1KB8 MREENKGMPSGGGSDEG----LASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVMMM :..:.: : ::.::::: ::.:: :::::: ::. : .::: :::::: CCDS56 MEPAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQVMMM 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 DSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLP ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 GSARVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLP 60 70 80 90 100 110 120 130 pF1KB8 VDLAEERGHRDVAGYLRTATGD :::::: :::::: :::.:.: CCDS56 VDLAEELGHRDVARYLRAAAGGTRGSNHARIDAAEGPSEMIGNHLWVCRSRHA 120 130 140 150 160 >>CCDS6513.1 CDKN2B gene_id:1030|Hs108|chr9 (78 aa) initn: 387 init1: 344 opt: 344 Z-score: 384.4 bits: 76.1 E(32554): 4.3e-15 Smith-Waterman score: 344; 100.0% identity (100.0% similar) in 53 aa overlap (1-53:1-53) 10 20 30 40 50 60 pF1KB8 MREENKGMPSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVMMMDSAR ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 MREENKGMPSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPGPR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 VAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLA CCDS65 RQGARERGARPRRIGAGT 70 >>CCDS12244.1 CDKN2D gene_id:1032|Hs108|chr19 (166 aa) initn: 363 init1: 208 opt: 333 Z-score: 368.2 bits: 74.2 E(32554): 3.5e-14 Smith-Waterman score: 333; 50.9% identity (75.0% similar) in 116 aa overlap (18-132:12-126) 10 20 30 40 50 pF1KB8 MREENKGMPSGGGSDEGLASAAARGLVEKVRQLLEAG-ADPNGVNRFGRRAIQVMMMDSA :..::::: :..::.::. . :...::::. :.::::. :. CCDS12 MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGST 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 RVAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDL .: :: .:: :: : .. : ::::::: :::::: :: . :: ..: :. : ::. : CCDS12 AIALELLKQGASPNVQD-TSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHL 60 70 80 90 100 110 120 130 pF1KB8 AEERGHRDVAGYLRTATGD : ..:: :...: CCDS12 AVQEGHTAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL 120 130 140 150 160 >>CCDS555.1 CDKN2C gene_id:1031|Hs108|chr1 (168 aa) initn: 301 init1: 167 opt: 289 Z-score: 321.8 bits: 65.6 E(32554): 1.3e-11 Smith-Waterman score: 289; 44.3% identity (73.0% similar) in 115 aa overlap (18-132:9-122) 10 20 30 40 50 60 pF1KB8 MREENKGMPSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVMMMDSAR :::::::: .:.. .::. ... :. : ::: :.::: . . . CCDS55 MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPE 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 VAELLLLHGAEPNCADPATLTRPVHDAAREGFLDTLVVLHRAGARLDVRDAWGRLPVDLA .:. :::.::.:. : . .. .::::: :::::: .: . : ....: : ::. :: CCDS55 IARRLLLRGANPDLKDRTGFAV-IHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLA 60 70 80 90 100 110 130 pF1KB8 EERGHRDVAGYLRTATGD ..:: :. .: CCDS55 AKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ 120 130 140 150 160 138 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 01:32:50 2016 done: Sat Nov 5 01:32:50 2016 Total Scan time: 1.720 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]