FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8435, 503 aa 1>>>pF1KB8435 503 - 503 aa - 503 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.8388+/-0.00132; mu= 5.6292+/- 0.076 mean_var=245.4816+/-56.420, 0's: 0 Z-trim(107.0): 654 B-trim: 108 in 1/50 Lambda= 0.081859 statistics sampled from 8504 (9285) to 8504 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.647), E-opt: 0.2 (0.285), width: 16 Scan time: 2.520 The best scores are: opt bits E(32554) CCDS5486.1 CAMK2B gene_id:816|Hs108|chr7 ( 503) 3380 413.3 3.1e-115 CCDS7336.1 CAMK2G gene_id:818|Hs108|chr10 ( 495) 2960 363.7 2.6e-100 CCDS5485.1 CAMK2B gene_id:816|Hs108|chr7 ( 518) 2369 294.0 2.7e-79 CCDS43573.1 CAMK2B gene_id:816|Hs108|chr7 ( 517) 2352 291.9 1.1e-78 CCDS5488.1 CAMK2B gene_id:816|Hs108|chr7 ( 479) 2222 276.6 4.4e-74 CCDS5489.1 CAMK2B gene_id:816|Hs108|chr7 ( 449) 2145 267.4 2.3e-71 CCDS5484.1 CAMK2B gene_id:816|Hs108|chr7 ( 542) 2135 266.3 5.9e-71 CCDS5487.1 CAMK2B gene_id:816|Hs108|chr7 ( 492) 2133 266.1 6.5e-71 CCDS5483.1 CAMK2B gene_id:816|Hs108|chr7 ( 666) 2135 266.5 6.7e-71 CCDS82948.1 CAMK2D gene_id:817|Hs108|chr4 ( 512) 2114 263.8 3.2e-70 CCDS82949.1 CAMK2D gene_id:817|Hs108|chr4 ( 533) 2114 263.9 3.3e-70 CCDS7338.1 CAMK2G gene_id:818|Hs108|chr10 ( 556) 2077 259.5 6.9e-69 CCDS47127.1 CAMK2D gene_id:817|Hs108|chr4 ( 492) 2053 256.6 4.6e-68 CCDS3704.1 CAMK2D gene_id:817|Hs108|chr4 ( 478) 2052 256.5 4.9e-68 CCDS43263.1 CAMK2D gene_id:817|Hs108|chr4 ( 478) 2052 256.5 4.9e-68 CCDS3703.1 CAMK2D gene_id:817|Hs108|chr4 ( 499) 2052 256.5 5e-68 CCDS54797.1 CAMK2D gene_id:817|Hs108|chr4 ( 489) 2046 255.8 8.1e-68 CCDS82950.1 CAMK2D gene_id:817|Hs108|chr4 ( 498) 2035 254.5 2e-67 CCDS43386.1 CAMK2A gene_id:815|Hs108|chr5 ( 478) 2005 250.9 2.3e-66 CCDS43387.1 CAMK2A gene_id:815|Hs108|chr5 ( 489) 1999 250.2 3.8e-66 CCDS73153.1 CAMK2G gene_id:818|Hs108|chr10 ( 539) 1976 247.6 2.6e-65 CCDS7337.1 CAMK2G gene_id:818|Hs108|chr10 ( 527) 1967 246.5 5.4e-65 CCDS48094.1 CASK gene_id:8573|Hs108|chrX ( 897) 931 124.4 5.2e-28 CCDS48095.1 CASK gene_id:8573|Hs108|chrX ( 898) 931 124.4 5.2e-28 CCDS14257.1 CASK gene_id:8573|Hs108|chrX ( 921) 931 124.4 5.3e-28 CCDS7091.1 CAMK1D gene_id:57118|Hs108|chr10 ( 385) 801 108.6 1.3e-23 CCDS4103.1 CAMK4 gene_id:814|Hs108|chr5 ( 473) 800 108.6 1.6e-23 CCDS7092.1 CAMK1D gene_id:57118|Hs108|chr10 ( 357) 785 106.7 4.4e-23 CCDS1486.1 CAMK1G gene_id:57172|Hs108|chr1 ( 476) 752 102.9 8e-22 CCDS2582.1 CAMK1 gene_id:8536|Hs108|chr3 ( 370) 738 101.2 2.1e-21 CCDS55895.1 DCLK1 gene_id:9201|Hs108|chr13 ( 433) 734 100.8 3.3e-21 CCDS48189.1 PNCK gene_id:139728|Hs108|chrX ( 360) 732 100.4 3.4e-21 CCDS35503.2 PNCK gene_id:139728|Hs108|chrX ( 426) 732 100.5 3.8e-21 CCDS81762.1 DCLK1 gene_id:9201|Hs108|chr13 ( 740) 734 101.1 4.6e-21 CCDS34076.1 DCLK2 gene_id:166614|Hs108|chr4 ( 766) 734 101.1 4.7e-21 CCDS47142.2 DCLK2 gene_id:166614|Hs108|chr4 ( 783) 734 101.1 4.8e-21 CCDS73561.1 DCLK1 gene_id:9201|Hs108|chr13 ( 422) 720 99.1 1e-20 CCDS9354.1 DCLK1 gene_id:9201|Hs108|chr13 ( 729) 720 99.4 1.4e-20 CCDS10851.1 PSKH1 gene_id:5681|Hs108|chr16 ( 424) 714 98.4 1.7e-20 CCDS43064.1 DCLK3 gene_id:85443|Hs108|chr3 ( 648) 709 98.0 3.3e-20 CCDS33762.1 CAMKV gene_id:79012|Hs108|chr3 ( 501) 657 91.8 2e-18 CCDS82776.1 CAMKV gene_id:79012|Hs108|chr3 ( 470) 650 90.9 3.3e-18 CCDS10188.1 DAPK2 gene_id:23604|Hs108|chr15 ( 370) 643 89.9 5.1e-18 CCDS43842.1 DAPK1 gene_id:1612|Hs108|chr9 (1430) 641 90.4 1.4e-17 CCDS12921.1 BRSK1 gene_id:84446|Hs108|chr19 ( 778) 631 88.9 2.2e-17 CCDS12116.1 DAPK3 gene_id:1613|Hs108|chr19 ( 454) 626 88.0 2.3e-17 CCDS41590.1 BRSK2 gene_id:9024|Hs108|chr11 ( 668) 611 86.5 1e-16 CCDS58106.1 BRSK2 gene_id:9024|Hs108|chr11 ( 674) 611 86.5 1e-16 CCDS58107.1 BRSK2 gene_id:9024|Hs108|chr11 ( 736) 611 86.5 1.1e-16 CCDS6240.1 PSKH2 gene_id:85481|Hs108|chr8 ( 385) 598 84.7 2.1e-16 >>CCDS5486.1 CAMK2B gene_id:816|Hs108|chr7 (503 aa) initn: 3380 init1: 3380 opt: 3380 Z-score: 2182.3 bits: 413.3 E(32554): 3.1e-115 Smith-Waterman score: 3380; 100.0% identity (100.0% similar) in 503 aa overlap (1-503:1-503) 10 20 30 40 50 60 pF1KB8 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 KGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALESSDSAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 KGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALESSDSAN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 TTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 RFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 RFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVW 430 440 450 460 470 480 490 500 pF1KB8 HRRDGKWQNVHFHCSGAPVAPLQ ::::::::::::::::::::::: CCDS54 HRRDGKWQNVHFHCSGAPVAPLQ 490 500 >>CCDS7336.1 CAMK2G gene_id:818|Hs108|chr10 (495 aa) initn: 2046 init1: 2046 opt: 2960 Z-score: 1914.4 bits: 363.7 E(32554): 2.6e-100 Smith-Waterman score: 2960; 87.9% identity (94.1% similar) in 505 aa overlap (1-503:1-495) 10 20 30 40 50 60 pF1KB8 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER ::::.:::::::.:::.:..::::::::::::: . .:::::::::::::::::::::: CCDS73 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::.:: CCDS73 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY ::.: : :: .::::::::::::::::::::::::::::::::::.::::::::::::: CCDS73 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT ::::::::. :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL ::::::::::::::::::::::: .::::::::::::::::::::::::::.:::::::: CCDS73 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 KGAILTTMLATRNFSAAKSLLNKKADG-VK-PQTNSTKNSAAATSPKGTLPPAALESSDS :::::::::..:::::::::::::.:: :: :::. ..: :. . :: :..: CCDS73 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKEPQTTVVHN--ATDGIKG--------STES 310 320 330 340 350 360 370 380 390 400 410 pF1KB8 ANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMD ::: :::: :.::::::: :::::::.::::::::.::::::::::::::::::::::: CCDS73 CNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMD 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB8 FHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETR ::.:::::::.::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 FHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETR 420 430 440 450 460 470 480 490 500 pF1KB8 VWHRRDGKWQNVHFHCSGAPVAPLQ ::::::::: :::.::::::.:::: CCDS73 VWHRRDGKWLNVHYHCSGAPAAPLQ 480 490 >>CCDS5485.1 CAMK2B gene_id:816|Hs108|chr7 (518 aa) initn: 2369 init1: 2369 opt: 2369 Z-score: 1536.9 bits: 294.0 E(32554): 2.7e-79 Smith-Waterman score: 3340; 97.1% identity (97.1% similar) in 518 aa overlap (1-503:1-518) 10 20 30 40 50 60 pF1KB8 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 KGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALE------ :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 KGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVI 310 320 330 340 350 360 360 370 380 390 400 pF1KB8 ---------SSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSF ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 HNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSF 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB8 EPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 EPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 430 440 450 460 470 480 470 480 490 500 pF1KB8 QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ :::::::::::::::::::::::::::::::::::::: CCDS54 QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 490 500 510 >>CCDS43573.1 CAMK2B gene_id:816|Hs108|chr7 (517 aa) initn: 3146 init1: 2143 opt: 2352 Z-score: 1526.1 bits: 291.9 E(32554): 1.1e-78 Smith-Waterman score: 3323; 96.9% identity (96.9% similar) in 518 aa overlap (1-503:1-517) 10 20 30 40 50 60 pF1KB8 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 KGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALE------ :::::::::::::::: ::::::::::::::::::::::::::::::::::::: CCDS43 KGAILTTMLATRNFSA-KSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALEPQTTVI 310 320 330 340 350 360 370 380 390 400 pF1KB8 ---------SSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSF ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 HNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSF 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB8 EPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 EPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDG 420 430 440 450 460 470 470 480 490 500 pF1KB8 QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ :::::::::::::::::::::::::::::::::::::: CCDS43 QGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 480 490 500 510 >>CCDS5488.1 CAMK2B gene_id:816|Hs108|chr7 (479 aa) initn: 2222 init1: 2222 opt: 2222 Z-score: 1443.5 bits: 276.6 E(32554): 4.4e-74 Smith-Waterman score: 3171; 95.2% identity (95.2% similar) in 503 aa overlap (1-503:1-479) 10 20 30 40 50 60 pF1KB8 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 KGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALESSDSAN ::::::::::::::::::::::::::::: ::::::: CCDS54 KGAILTTMLATRNFSAAKSLLNKKADGVK------------------------ESSDSAN 310 320 330 370 380 390 400 410 420 pF1KB8 TTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 TTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFH 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB8 RFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 RFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVW 400 410 420 430 440 450 490 500 pF1KB8 HRRDGKWQNVHFHCSGAPVAPLQ ::::::::::::::::::::::: CCDS54 HRRDGKWQNVHFHCSGAPVAPLQ 460 470 >>CCDS5489.1 CAMK2B gene_id:816|Hs108|chr7 (449 aa) initn: 2142 init1: 2142 opt: 2145 Z-score: 1394.7 bits: 267.4 E(32554): 2.3e-71 Smith-Waterman score: 2934; 89.3% identity (89.3% similar) in 503 aa overlap (1-503:1-449) 10 20 30 40 50 60 pF1KB8 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 KGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALESSDSAN :::::::::::::::: CCDS54 KGAILTTMLATRNFSA-------------------------------------------- 310 370 380 390 400 410 420 pF1KB8 TTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFH :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 ----------RKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFH 320 330 340 350 360 430 440 450 460 470 480 pF1KB8 RFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 RFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVW 370 380 390 400 410 420 490 500 pF1KB8 HRRDGKWQNVHFHCSGAPVAPLQ ::::::::::::::::::::::: CCDS54 HRRDGKWQNVHFHCSGAPVAPLQ 430 440 >>CCDS5484.1 CAMK2B gene_id:816|Hs108|chr7 (542 aa) initn: 3136 init1: 2133 opt: 2135 Z-score: 1387.4 bits: 266.3 E(32554): 5.9e-71 Smith-Waterman score: 3230; 92.5% identity (92.7% similar) in 535 aa overlap (1-496:1-535) 10 20 30 40 50 60 pF1KB8 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 250 260 270 280 290 300 310 320 330 pF1KB8 KGAILTTMLATRNFSA------------------------AKSLLNKKADGVKPQTNSTK :::::::::::::::. :::::::::::::::::::: CCDS54 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 310 320 330 340 350 360 340 350 360 370 380 pF1KB8 NSAAATSPKGTLPPAALE---------------SSDSANTTIEDEDAKARKQEIIKTTEQ :::::::::::::::::: ::::::::::::::::::::::::::: CCDS54 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKARKQEIIKTTEQ 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB8 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILN 430 440 450 460 470 480 450 460 470 480 490 500 pF1KB8 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 PHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAP 490 500 510 520 530 540 pF1KB8 LQ CCDS54 LQ >>CCDS5487.1 CAMK2B gene_id:816|Hs108|chr7 (492 aa) initn: 3001 init1: 2133 opt: 2133 Z-score: 1386.6 bits: 266.1 E(32554): 6.5e-71 Smith-Waterman score: 2900; 86.4% identity (87.5% similar) in 528 aa overlap (1-503:1-492) 10 20 30 40 50 60 pF1KB8 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 250 260 270 280 290 300 310 320 330 pF1KB8 KGAILTTMLATRNFSA------------------------AKSLLNKKADGVK-PQTNST :::::::::::::::. ::::::::::::: :::. CCDS54 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKEPQTTVI 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB8 KNSAAATSPKGTLPPAALESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYA .: . . . :::::::::::::::::::::::::::::::::::::::::: CCDS54 HNPVDGIK----------ESSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYA 370 380 390 400 410 400 410 420 430 440 450 pF1KB8 KICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIA :::::::::::::::::::::::::::::::::: CCDS54 --------------------------FYFENLLAKNSKPIHTTILNPHVHVIGEDAACIA 420 430 440 460 470 480 490 500 pF1KB8 YIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ :::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 YIRLTQYIDGQGRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 450 460 470 480 490 >>CCDS5483.1 CAMK2B gene_id:816|Hs108|chr7 (666 aa) initn: 3257 init1: 2133 opt: 2135 Z-score: 1386.3 bits: 266.5 E(32554): 6.7e-71 Smith-Waterman score: 2370; 84.3% identity (87.5% similar) in 447 aa overlap (1-407:1-442) 10 20 30 40 50 60 pF1KB8 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 250 260 270 280 290 300 310 320 330 pF1KB8 KGAILTTMLATRNFSA------------------------AKSLLNKKADGVKPQTNSTK :::::::::::::::. :::::::::::::::::::: CCDS54 KGAILTTMLATRNFSVGRQTTAPATMSTAASGTTMGLVEQAKSLLNKKADGVKPQTNSTK 310 320 330 340 350 360 340 350 360 370 380 pF1KB8 NSAAATSPKGTLPPAALE---------------SSDSANTTIEDEDAKA-RKQEIIKTTE :::::::::::::::::: :::::::::::::::: : .:..... CCDS54 NSAAATSPKGTLPPAALEPQTTVIHNPVDGIKESSDSANTTIEDEDAKAPRVPDILSSVR 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB8 QLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFHRFYFENLLAKNSKPIHTTIL . ..: :: . . :. . : : CCDS54 R-----GSGAPEAEGPLPCPSPAPFSPLPAPSPRISDILNSVRRGSGTPEAEGPLSAGPP 430 440 450 460 470 >-- initn: 970 init1: 918 opt: 920 Z-score: 610.9 bits: 123.0 E(32554): 1.1e-27 Smith-Waterman score: 920; 76.1% identity (85.3% similar) in 184 aa overlap (321-503:486-666) 300 310 320 330 340 350 pF1KB8 LKKFNARRKLKGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPP :.. . .. ::.. .... .: : CCDS54 SVRRGSGTPEAEGPLSAGPPPCLSPALLGPLSSPSPRISDILNSVRRGSGTPEAEG---P 460 470 480 490 500 510 360 370 380 390 400 pF1KB8 AALESSDSANTTIEDE-DAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEA . . . :: . .::::::::::::::::::::::::::::::::::::::: CCDS54 SPVGPPPCPSPTIPGPLPTPSRKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEA 520 530 540 550 560 570 410 420 430 440 450 460 pF1KB8 LGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRP 580 590 600 610 620 630 470 480 490 500 pF1KB8 RTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ :::::::::::::::::::::::::::::::::: CCDS54 RTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ 640 650 660 >>CCDS82948.1 CAMK2D gene_id:817|Hs108|chr4 (512 aa) initn: 2951 init1: 2051 opt: 2114 Z-score: 1374.2 bits: 263.8 E(32554): 3.2e-70 Smith-Waterman score: 2939; 84.9% identity (93.0% similar) in 517 aa overlap (1-503:1-512) 10 20 30 40 50 60 pF1KB8 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER ::.:.:::::::::::.:..:::::::::::.:. ::.:::::::::::::::::::::: CCDS82 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY ::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::: CCDS82 LEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT ::::::::. ::::::.:::::::::::::::::::::::.::::::::::::::::::: CCDS82 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL ::::::.:::.:::::::::::: :::::::.::::::::::::::::.::::::::::: CCDS82 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 KGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALE------ ::::::::::::::::::::: :: :::: :. : ..:::: ..: ::: CCDS82 KGAILTTMLATRNFSAAKSLL-KKPDGVK--INNKAN--VVTSPKENIPTPALEPQTTVI 310 320 330 340 350 360 370 380 390 400 pF1KB8 --------SSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFE :..:.::::::::.:::::::::.:::::::.::::::::.::::::::.:: CCDS82 HNPDGNKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFE 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB8 PEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQ :::::::::::::::::::: :.:..::::: :::::::..:.:::::::::::::.::. CCDS82 PEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGS 420 430 440 450 460 470 470 480 490 500 pF1KB8 GRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ : :.: ::::::::::::::::::::: ::.:..:.. CCDS82 GMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIK 480 490 500 510 503 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 01:33:23 2016 done: Sat Nov 5 01:33:23 2016 Total Scan time: 2.520 Total Display time: 0.080 Function used was FASTA [36.3.4 Apr, 2011]