FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8435, 503 aa 1>>>pF1KB8435 503 - 503 aa - 503 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.3703+/-0.000632; mu= -1.1585+/- 0.038 mean_var=605.7579+/-142.957, 0's: 0 Z-trim(114.5): 1769 B-trim: 505 in 1/52 Lambda= 0.052110 statistics sampled from 22041 (24439) to 22041 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.287), width: 16 Scan time: 8.430 The best scores are: opt bits E(85289) NP_742078 (OMIM: 607707) calcium/calmodulin-depend ( 503) 3380 270.4 8.6e-72 XP_016868153 (OMIM: 607707) PREDICTED: calcium/cal ( 502) 3363 269.1 2.1e-71 NP_751913 (OMIM: 602123) calcium/calmodulin-depend ( 504) 2983 240.6 8.3e-63 NP_001213 (OMIM: 602123) calcium/calmodulin-depend ( 495) 2960 238.8 2.7e-62 XP_016872224 (OMIM: 602123) PREDICTED: calcium/cal ( 506) 2960 238.8 2.8e-62 NP_001308497 (OMIM: 607708) calcium/calmodulin-dep ( 503) 2947 237.8 5.4e-62 NP_001308509 (OMIM: 607708) calcium/calmodulin-dep ( 519) 2945 237.7 6.1e-62 XP_005263311 (OMIM: 607708) PREDICTED: calcium/cal ( 532) 2922 236.0 2.1e-61 XP_016864163 (OMIM: 607708) PREDICTED: calcium/cal ( 511) 2920 235.8 2.2e-61 NP_001308520 (OMIM: 607708) calcium/calmodulin-dep ( 503) 2917 235.6 2.6e-61 NP_001308502 (OMIM: 607708) calcium/calmodulin-dep ( 524) 2917 235.6 2.7e-61 NP_001308516 (OMIM: 607708) calcium/calmodulin-dep ( 503) 2915 235.4 2.9e-61 XP_005263310 (OMIM: 607708) PREDICTED: calcium/cal ( 532) 2890 233.6 1.1e-60 NP_001308515 (OMIM: 607708) calcium/calmodulin-dep ( 511) 2888 233.4 1.2e-60 XP_016868159 (OMIM: 607707) PREDICTED: calcium/cal ( 374) 2522 205.7 2e-52 XP_016868149 (OMIM: 607707) PREDICTED: calcium/cal ( 670) 2473 202.4 3.3e-51 XP_006715844 (OMIM: 607707) PREDICTED: calcium/cal ( 626) 2456 201.1 7.8e-51 XP_011513856 (OMIM: 607707) PREDICTED: calcium/cal ( 669) 2456 201.1 8.1e-51 NP_742076 (OMIM: 607707) calcium/calmodulin-depend ( 518) 2369 194.4 6.7e-49 XP_011513852 (OMIM: 607707) PREDICTED: calcium/cal ( 685) 2369 194.6 7.6e-49 NP_742077 (OMIM: 607707) calcium/calmodulin-depend ( 517) 2352 193.1 1.6e-48 XP_016868151 (OMIM: 607707) PREDICTED: calcium/cal ( 603) 2352 193.2 1.7e-48 XP_011513854 (OMIM: 607707) PREDICTED: calcium/cal ( 684) 2352 193.3 1.8e-48 XP_011513858 (OMIM: 607707) PREDICTED: calcium/cal ( 661) 2240 184.9 6.2e-46 XP_005249921 (OMIM: 607707) PREDICTED: calcium/cal ( 494) 2230 183.9 9.1e-46 NP_742080 (OMIM: 607707) calcium/calmodulin-depend ( 479) 2222 183.3 1.4e-45 XP_011513859 (OMIM: 607707) PREDICTED: calcium/cal ( 660) 2223 183.6 1.5e-45 XP_016868154 (OMIM: 607707) PREDICTED: calcium/cal ( 493) 2213 182.6 2.2e-45 NP_742081 (OMIM: 607707) calcium/calmodulin-depend ( 449) 2145 177.5 7.3e-44 XP_016868150 (OMIM: 607707) PREDICTED: calcium/cal ( 656) 2138 177.2 1.3e-43 XP_005249919 (OMIM: 607707) PREDICTED: calcium/cal ( 527) 2135 176.8 1.3e-43 NP_742075 (OMIM: 607707) calcium/calmodulin-depend ( 542) 2135 176.9 1.3e-43 NP_001280099 (OMIM: 607707) calcium/calmodulin-dep ( 542) 2135 176.9 1.3e-43 XP_011513860 (OMIM: 607707) PREDICTED: calcium/cal ( 607) 2135 176.9 1.4e-43 NP_742079 (OMIM: 607707) calcium/calmodulin-depend ( 492) 2133 176.6 1.4e-43 XP_006715847 (OMIM: 607707) PREDICTED: calcium/cal ( 518) 2133 176.7 1.5e-43 XP_011513857 (OMIM: 607707) PREDICTED: calcium/cal ( 666) 2135 177.0 1.5e-43 NP_001211 (OMIM: 607707) calcium/calmodulin-depend ( 666) 2135 177.0 1.5e-43 XP_011513855 (OMIM: 607707) PREDICTED: calcium/cal ( 671) 2135 177.0 1.5e-43 XP_011513851 (OMIM: 607707) PREDICTED: calcium/cal ( 694) 2135 177.0 1.5e-43 XP_011513849 (OMIM: 607707) PREDICTED: calcium/cal ( 709) 2135 177.1 1.5e-43 XP_011513853 (OMIM: 607707) PREDICTED: calcium/cal ( 685) 2133 176.9 1.7e-43 NP_001308496 (OMIM: 607708) calcium/calmodulin-dep ( 512) 2114 175.2 3.9e-43 NP_001308501 (OMIM: 607708) calcium/calmodulin-dep ( 512) 2114 175.2 3.9e-43 NP_001308500 (OMIM: 607708) calcium/calmodulin-dep ( 533) 2114 175.3 4e-43 XP_005270258 (OMIM: 602123) PREDICTED: calcium/cal ( 542) 2109 174.9 5.2e-43 XP_016872215 (OMIM: 602123) PREDICTED: calcium/cal ( 569) 2109 174.9 5.3e-43 XP_005270257 (OMIM: 602123) PREDICTED: calcium/cal ( 544) 2086 173.2 1.7e-42 NP_001308512 (OMIM: 607708) calcium/calmodulin-dep ( 492) 2085 173.0 1.7e-42 NP_001308504 (OMIM: 607708) calcium/calmodulin-dep ( 492) 2085 173.0 1.7e-42 >>NP_742078 (OMIM: 607707) calcium/calmodulin-dependent (503 aa) initn: 3380 init1: 3380 opt: 3380 Z-score: 1409.8 bits: 270.4 E(85289): 8.6e-72 Smith-Waterman score: 3380; 100.0% identity (100.0% similar) in 503 aa overlap (1-503:1-503) 10 20 30 40 50 60 pF1KB8 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_742 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_742 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_742 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_742 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_742 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 KGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALESSDSAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_742 KGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALESSDSAN 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_742 TTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 RFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_742 RFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVW 430 440 450 460 470 480 490 500 pF1KB8 HRRDGKWQNVHFHCSGAPVAPLQ ::::::::::::::::::::::: NP_742 HRRDGKWQNVHFHCSGAPVAPLQ 490 500 >>XP_016868153 (OMIM: 607707) PREDICTED: calcium/calmodu (502 aa) initn: 2138 init1: 2138 opt: 3363 Z-score: 1402.9 bits: 269.1 E(85289): 2.1e-71 Smith-Waterman score: 3363; 99.8% identity (99.8% similar) in 503 aa overlap (1-503:1-502) 10 20 30 40 50 60 pF1KB8 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 KGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALESSDSAN :::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::: XP_016 KGAILTTMLATRNFSA-KSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALESSDSAN 310 320 330 340 350 370 380 390 400 410 420 pF1KB8 TTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFH 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB8 RFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVW 420 430 440 450 460 470 490 500 pF1KB8 HRRDGKWQNVHFHCSGAPVAPLQ ::::::::::::::::::::::: XP_016 HRRDGKWQNVHFHCSGAPVAPLQ 480 490 500 >>NP_751913 (OMIM: 602123) calcium/calmodulin-dependent (504 aa) initn: 2041 init1: 2041 opt: 2983 Z-score: 1248.5 bits: 240.6 E(85289): 8.3e-63 Smith-Waterman score: 2983; 87.8% identity (93.9% similar) in 508 aa overlap (1-503:1-504) 10 20 30 40 50 60 pF1KB8 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER ::::.:::::::.:::.:..::::::::::::: . .:::::::::::::::::::::: NP_751 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::.:: NP_751 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY ::.: : :: .::::::::::::::::::::::::::::::::::.::::::::::::: NP_751 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT ::::::::. :::::::::::::::::::::::::::::::::::::::::::::::::: NP_751 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL ::::::::::::::::::::::: .::::::::::::::::::::::::::.:::::::: NP_751 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 KGAILTTMLATRNFSAAKSLLNKKADG-VKPQTNSTKNSAAATSPKGTLPPAALE----S :::::::::..:::::::::::::.:: ::::.:. ::: :. :. : . : NP_751 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKPQSNN-KNS---LEPQTTVVHNATDGIKGS 310 320 330 340 350 360 370 380 390 400 410 pF1KB8 SDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVE ..: ::: :::: :.::::::: :::::::.::::::::.:::::::::::::::::::: NP_751 TESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVE 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB8 GMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSE :::::.:::::::.:::::::::::::::::::::::::::::::::::::::::::::: NP_751 GMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSE 420 430 440 450 460 470 480 490 500 pF1KB8 ETRVWHRRDGKWQNVHFHCSGAPVAPLQ :::::::::::: :::.::::::.:::: NP_751 ETRVWHRRDGKWLNVHYHCSGAPAAPLQ 480 490 500 >>NP_001213 (OMIM: 602123) calcium/calmodulin-dependent (495 aa) initn: 2046 init1: 2046 opt: 2960 Z-score: 1239.3 bits: 238.8 E(85289): 2.7e-62 Smith-Waterman score: 2960; 87.9% identity (94.1% similar) in 505 aa overlap (1-503:1-495) 10 20 30 40 50 60 pF1KB8 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER ::::.:::::::.:::.:..::::::::::::: . .:::::::::::::::::::::: NP_001 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::.:: NP_001 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY ::.: : :: .::::::::::::::::::::::::::::::::::.::::::::::::: NP_001 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT ::::::::. :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL ::::::::::::::::::::::: .::::::::::::::::::::::::::.:::::::: NP_001 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 KGAILTTMLATRNFSAAKSLLNKKADG-VK-PQTNSTKNSAAATSPKGTLPPAALESSDS :::::::::..:::::::::::::.:: :: :::. ..: :. . :: :..: NP_001 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKEPQTTVVHN--ATDGIKG--------STES 310 320 330 340 350 360 370 380 390 400 410 pF1KB8 ANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMD ::: :::: :.::::::: :::::::.::::::::.::::::::::::::::::::::: NP_001 CNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVEGMD 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB8 FHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETR ::.:::::::.::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETR 420 430 440 450 460 470 480 490 500 pF1KB8 VWHRRDGKWQNVHFHCSGAPVAPLQ ::::::::: :::.::::::.:::: NP_001 VWHRRDGKWLNVHYHCSGAPAAPLQ 480 490 >>XP_016872224 (OMIM: 602123) PREDICTED: calcium/calmodu (506 aa) initn: 2958 init1: 2032 opt: 2960 Z-score: 1239.2 bits: 238.8 E(85289): 2.8e-62 Smith-Waterman score: 2960; 87.0% identity (93.5% similar) in 508 aa overlap (1-503:1-506) 10 20 30 40 50 60 pF1KB8 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER ::::.:::::::.:::.:..::::::::::::: . .:::::::::::::::::::::: XP_016 MATTATCTRFTDDYQLFEELGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::.:: XP_016 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY ::.: : :: .::::::::::::::::::::::::::::::::::.::::::::::::: XP_016 LESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQQAWFGFAGTPGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT ::::::::. :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL ::::::::::::::::::::::: .::::::::::::::::::::::::::.:::::::: XP_016 VTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETVECLRKFNARRKL 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 KGAILTTMLATRNFSAAKSLLNKKADG-VKPQTNSTKNSAAATSPKGTLPPAALE----S :::::::::..:::::::::::::.:: :: . .:. :. :. :. : . : XP_016 KGAILTTMLVSRNFSAAKSLLNKKSDGGVKKRKSSS--SVHLMEPQTTVVHNATDGIKGS 310 320 330 340 350 360 370 380 390 400 410 pF1KB8 SDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVE ..: ::: :::: :.::::::: :::::::.::::::::.:::::::::::::::::::: XP_016 TESCNTTTEDEDLKVRKQEIIKITEQLIEAINNGDFEAYTKICDPGLTSFEPEALGNLVE 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB8 GMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSE :::::.:::::::.:::::::::::::::::::::::::::::::::::::::::::::: XP_016 GMDFHKFYFENLLSKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSE 420 430 440 450 460 470 480 490 500 pF1KB8 ETRVWHRRDGKWQNVHFHCSGAPVAPLQ :::::::::::: :::.::::::.:::: XP_016 ETRVWHRRDGKWLNVHYHCSGAPAAPLQ 480 490 500 >>NP_001308497 (OMIM: 607708) calcium/calmodulin-depende (503 aa) initn: 2947 init1: 2916 opt: 2947 Z-score: 1233.9 bits: 237.8 E(85289): 5.4e-62 Smith-Waterman score: 2947; 86.1% identity (94.7% similar) in 505 aa overlap (1-502:1-502) 10 20 30 40 50 60 pF1KB8 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER ::.:.:::::::::::.:..:::::::::::.:. ::.:::::::::::::::::::::: NP_001 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY ::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::: NP_001 LEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT ::::::::. ::::::.:::::::::::::::::::::::.::::::::::::::::::: NP_001 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL ::::::.:::.:::::::::::: :::::::.::::::::::::::::.::::::::::: NP_001 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 KGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTL---PPAALESSD ::::::::::::::::::::: :: :::: . .:. :. :. :. : . ::.. NP_001 KGAILTTMLATRNFSAAKSLL-KKPDGVKKRKSSS--SVQMMEPQTTVIHNPDGNKESTE 310 320 330 340 350 360 370 380 390 400 410 pF1KB8 SANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGM :.::::::::.:::::::::.:::::::.::::::::.::::::::.::::::::::::: NP_001 SSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGM 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB8 DFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEET ::::::::: :.:..::::: :::::::..:.:::::::::::::.::.: :.: ::::: NP_001 DFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEET 420 430 440 450 460 470 480 490 500 pF1KB8 RVWHRRDGKWQNVHFHCSGAPVAPLQ :::::::::::::::: ::.:..:. NP_001 RVWHRRDGKWQNVHFHRSGSPTVPIN 480 490 500 >>NP_001308509 (OMIM: 607708) calcium/calmodulin-depende (519 aa) initn: 2927 init1: 2019 opt: 2945 Z-score: 1233.0 bits: 237.7 E(85289): 6.1e-62 Smith-Waterman score: 2945; 86.3% identity (95.0% similar) in 503 aa overlap (1-503:1-498) 10 20 30 40 50 60 pF1KB8 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER ::.:.:::::::::::.:..:::::::::::.:. ::.:::::::::::::::::::::: NP_001 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY ::.: ::: :.::::::::::::::: :::::::::::::::::::::::::::::::: NP_001 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT ::::::::. ::::::.:::::::::::::::::::::::.::::::::::::::::::: NP_001 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL ::::::.:::.:::::::::::: :::::::.::::::::::::::::.::::::::::: NP_001 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 KGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALESSDSAN ::::::::::::::::::::: :: :::: :. : ..:::: ..: ::::..:.: NP_001 KGAILTTMLATRNFSAAKSLL-KKPDGVK--INNKAN--VVTSPKENIPTPALESTESSN 310 320 330 340 350 370 380 390 400 410 420 pF1KB8 TTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGMDFH :::::::.:::::::::.:::::::.::::::::.::::::::.:::::::::::::::: NP_001 TTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFH 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB8 RFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEETRVW :::::: :.:..::::: :::::::..:.:::::::::::::.::.: :.: :::::::: NP_001 RFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEETRVW 420 430 440 450 460 470 490 500 pF1KB8 HRRDGKWQNVHFHCSGAPVAPLQ ::::::::::::: ::.:..:.. NP_001 HRRDGKWQNVHFHRSGSPTVPIKPPCIPNGKENFSGGTSLWQNI 480 490 500 510 >>XP_005263311 (OMIM: 607708) PREDICTED: calcium/calmodu (532 aa) initn: 2899 init1: 2034 opt: 2922 Z-score: 1223.5 bits: 236.0 E(85289): 2.1e-61 Smith-Waterman score: 2922; 84.7% identity (92.8% similar) in 517 aa overlap (1-503:1-511) 10 20 30 40 50 60 pF1KB8 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER ::.:.:::::::::::.:..:::::::::::.:. ::.:::::::::::::::::::::: XP_005 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY ::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::: XP_005 LEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT ::::::::. ::::::.:::::::::::::::::::::::.::::::::::::::::::: XP_005 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL ::::::.:::.:::::::::::: :::::::.::::::::::::::::.::::::::::: XP_005 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 KGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALE------ :::::::::::::::: :::: :: :::: :. : ..:::: ..: ::: XP_005 KGAILTTMLATRNFSA-KSLL-KKPDGVK--INNKAN--VVTSPKENIPTPALEPQTTVI 310 320 330 340 350 360 370 380 390 400 pF1KB8 --------SSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFE :..:.::::::::.:::::::::.:::::::.::::::::.::::::::.:: XP_005 HNPDGNKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFE 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB8 PEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQ :::::::::::::::::::: :.:..::::: :::::::..:.:::::::::::::.::. XP_005 PEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGS 420 430 440 450 460 470 470 480 490 500 pF1KB8 GRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ : :.: ::::::::::::::::::::: ::.:..:.. XP_005 GMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIKPPCIPNGKENFSGGTSLWQNI 480 490 500 510 520 530 >>XP_016864163 (OMIM: 607708) PREDICTED: calcium/calmodu (511 aa) initn: 2897 init1: 2034 opt: 2920 Z-score: 1222.9 bits: 235.8 E(85289): 2.2e-61 Smith-Waterman score: 2920; 84.9% identity (92.8% similar) in 516 aa overlap (1-502:1-510) 10 20 30 40 50 60 pF1KB8 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER ::.:.:::::::::::.:..:::::::::::.:. ::.:::::::::::::::::::::: XP_016 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY ::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::: XP_016 LEAVLHCHQMGVVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT ::::::::. ::::::.:::::::::::::::::::::::.::::::::::::::::::: XP_016 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL ::::::.:::.:::::::::::: :::::::.::::::::::::::::.::::::::::: XP_016 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 KGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTLPPAALE------ :::::::::::::::: :::: :: :::: :. : ..:::: ..: ::: XP_016 KGAILTTMLATRNFSA-KSLL-KKPDGVK--INNKAN--VVTSPKENIPTPALEPQTTVI 310 320 330 340 350 360 370 380 390 400 pF1KB8 --------SSDSANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFE :..:.::::::::.:::::::::.:::::::.::::::::.::::::::.:: XP_016 HNPDGNKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFE 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB8 PEALGNLVEGMDFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQ :::::::::::::::::::: :.:..::::: :::::::..:.:::::::::::::.::. XP_016 PEALGNLVEGMDFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGS 420 430 440 450 460 470 470 480 490 500 pF1KB8 GRPRTSQSEETRVWHRRDGKWQNVHFHCSGAPVAPLQ : :.: ::::::::::::::::::::: ::.:..:. XP_016 GMPKTMQSEETRVWHRRDGKWQNVHFHRSGSPTVPIN 480 490 500 510 >>NP_001308520 (OMIM: 607708) calcium/calmodulin-depende (503 aa) initn: 2917 init1: 2886 opt: 2917 Z-score: 1221.7 bits: 235.6 E(85289): 2.6e-61 Smith-Waterman score: 2917; 85.0% identity (94.1% similar) in 506 aa overlap (1-503:1-503) 10 20 30 40 50 60 pF1KB8 MATTVTCTRFTDEYQLYEDIGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLER ::.:.:::::::::::.:..:::::::::::.:. ::.:::::::::::::::::::::: NP_001 MASTTTCTRFTDEYQLFEELGKGAFSVVRRCMKIPTGQEYAAKIINTKKLSARDHQKLER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 EARICRLLKHSNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EARICRLLKHPNIVRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LEAVLHCHQMGVVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY ::.: ::: :.::::::::::::::: :::::::::::::::::::::::::::::::: NP_001 LESVNHCHLNGIVHRDLKPENLLLASKSKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LSPEVLRKEAYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDT ::::::::. ::::::.:::::::::::::::::::::::.::::::::::::::::::: NP_001 LSPEVLRKDPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDT 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VTPEAKNLINQMLTINPAKRITAHEALKHPWVCQRSTVASMMHRQETVECLKKFNARRKL ::::::.:::.:::::::::::: :::::::.::::::::::::::::.::::::::::: NP_001 VTPEAKDLINKMLTINPAKRITASEALKHPWICQRSTVASMMHRQETVDCLKKFNARRKL 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 KGAILTTMLATRNFSAAKSLLNKKADGVKPQTNSTKNSAAATSPKGTL---PPAALESSD ::::::::::::::::::::: :: :::: . .:. :. :. :. : . ::.. NP_001 KGAILTTMLATRNFSAAKSLL-KKPDGVKKRKSSS--SVQMMEPQTTVIHNPDGNKESTE 310 320 330 340 350 360 370 380 390 400 410 pF1KB8 SANTTIEDEDAKARKQEIIKTTEQLIEAVNNGDFEAYAKICDPGLTSFEPEALGNLVEGM :.::::::::.:::::::::.:::::::.::::::::.::::::::.::::::::::::: NP_001 SSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGM 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB8 DFHRFYFENLLAKNSKPIHTTILNPHVHVIGEDAACIAYIRLTQYIDGQGRPRTSQSEET ::::::::: :.:..::::: :::::::..:.:::::::::::::.::.: :.: ::::: NP_001 DFHRFYFENALSKSNKPIHTIILNPHVHLVGDDAACIAYIRLTQYMDGSGMPKTMQSEET 420 430 440 450 460 470 480 490 500 pF1KB8 RVWHRRDGKWQNVHFHCSGAPVAPLQ :::::::::::::::: ::.:..:.. NP_001 RVWHRRDGKWQNVHFHRSGSPTVPIK 480 490 500 503 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 01:33:24 2016 done: Sat Nov 5 01:33:25 2016 Total Scan time: 8.430 Total Display time: 0.100 Function used was FASTA [36.3.4 Apr, 2011]