FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8436, 359 aa 1>>>pF1KB8436 359 - 359 aa - 359 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2276+/-0.00044; mu= 17.6490+/- 0.027 mean_var=77.5688+/-15.372, 0's: 0 Z-trim(110.4): 81 B-trim: 0 in 0/49 Lambda= 0.145623 statistics sampled from 18639 (18721) to 18639 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.582), E-opt: 0.2 (0.22), width: 16 Scan time: 7.550 The best scores are: opt bits E(85289) NP_002063 (OMIM: 163000,185300,600998) guanine nuc ( 359) 2361 505.8 5.8e-143 NP_002058 (OMIM: 139313) guanine nucleotide-bindin ( 359) 2159 463.4 3.5e-130 XP_016870117 (OMIM: 163000,185300,600998) PREDICTE ( 301) 1995 428.9 7.1e-120 NP_004288 (OMIM: 604397) guanine nucleotide-bindin ( 355) 1956 420.8 2.4e-117 XP_016870830 (OMIM: 604397) PREDICTED: guanine nuc ( 301) 1678 362.3 8e-100 XP_011517526 (OMIM: 604397) PREDICTED: guanine nuc ( 237) 1346 292.5 6.6e-79 NP_002059 (OMIM: 139314) guanine nucleotide-bindin ( 374) 1229 268.0 2.3e-71 NP_002060 (OMIM: 139310) guanine nucleotide-bindin ( 354) 1166 254.8 2.2e-67 NP_006487 (OMIM: 139370,602483) guanine nucleotide ( 354) 1144 250.2 5.3e-66 NP_620073 (OMIM: 139311,615473) guanine nucleotide ( 354) 1143 250.0 6.2e-66 NP_002061 (OMIM: 139360,192605) guanine nucleotide ( 355) 1142 249.7 7.2e-66 NP_066268 (OMIM: 139311,615473) guanine nucleotide ( 354) 1116 244.3 3.2e-64 XP_011539566 (OMIM: 139340,613856) PREDICTED: guan ( 354) 1110 243.0 7.6e-64 NP_005263 (OMIM: 139340,613856) guanine nucleotide ( 354) 1110 243.0 7.6e-64 NP_001095856 (OMIM: 139395) guanine nucleotide-bin ( 354) 1106 242.2 1.4e-63 NP_000163 (OMIM: 139330,610444,616389) guanine nuc ( 350) 1093 239.4 8.9e-63 NP_653082 (OMIM: 139330,610444,616389) guanine nuc ( 350) 1093 239.4 8.9e-63 NP_006563 (OMIM: 604406) guanine nucleotide-bindin ( 377) 1054 231.3 2.8e-60 NP_001159897 (OMIM: 139360,192605) guanine nucleot ( 318) 1042 228.7 1.4e-59 NP_001269549 (OMIM: 139360,192605) guanine nucleot ( 339) 1042 228.7 1.5e-59 NP_001269548 (OMIM: 139360,192605) guanine nucleot ( 339) 1042 228.7 1.5e-59 NP_002064 (OMIM: 139160) guanine nucleotide-bindin ( 355) 1034 227.1 4.8e-59 NP_031379 (OMIM: 604394) guanine nucleotide-bindin ( 381) 999 219.7 8.4e-57 NP_001243343 (OMIM: 139310) guanine nucleotide-bin ( 302) 991 218.0 2.2e-56 NP_001269546 (OMIM: 139360,192605) guanine nucleot ( 303) 974 214.4 2.7e-55 XP_011521305 (OMIM: 139311,615473) PREDICTED: guan ( 312) 954 210.2 5e-54 XP_011514426 (OMIM: 139395) PREDICTED: guanine nuc ( 297) 925 204.1 3.3e-52 NP_001269547 (OMIM: 139360,192605) guanine nucleot ( 274) 890 196.7 5.1e-50 NP_001269354 (OMIM: 604406) guanine nucleotide-bin ( 282) 829 183.9 3.8e-46 NP_892023 (OMIM: 139312,615073) guanine nucleotide ( 458) 822 182.6 1.5e-45 NP_001070957 (OMIM: 102200,103580,139320,166350,17 ( 379) 805 179.0 1.5e-44 NP_536351 (OMIM: 102200,103580,139320,166350,17480 ( 380) 799 177.7 3.7e-44 NP_001248372 (OMIM: 139312,615073) guanine nucleot ( 381) 798 177.5 4.3e-44 NP_001135811 (OMIM: 139312,615073) guanine nucleot ( 381) 798 177.5 4.3e-44 NP_001269370 (OMIM: 604394) guanine nucleotide-bin ( 322) 791 176.0 1.1e-43 XP_011513590 (OMIM: 604394) PREDICTED: guanine nuc ( 284) 787 175.1 1.7e-43 XP_016883303 (OMIM: 102200,103580,139320,166350,17 (1022) 758 169.4 3.1e-41 XP_016867497 (OMIM: 604394) PREDICTED: guanine nuc ( 253) 750 167.3 3.4e-41 XP_016883302 (OMIM: 102200,103580,139320,166350,17 (1023) 752 168.2 7.4e-41 XP_016883304 (OMIM: 102200,103580,139320,166350,17 ( 347) 720 161.1 3.4e-39 XP_016884275 (OMIM: 139160) PREDICTED: guanine nuc ( 307) 693 155.4 1.6e-37 XP_016883307 (OMIM: 102200,103580,139320,166350,17 ( 320) 652 146.8 6.5e-35 XP_016883308 (OMIM: 102200,103580,139320,166350,17 ( 320) 652 146.8 6.5e-35 XP_016883306 (OMIM: 102200,103580,139320,166350,17 ( 320) 652 146.8 6.5e-35 NP_001269369 (OMIM: 604394) guanine nucleotide-bin ( 305) 646 145.5 1.5e-34 NP_001296769 (OMIM: 102200,103580,139320,166350,17 ( 335) 620 140.1 7.1e-33 NP_001296790 (OMIM: 102200,103580,139320,166350,17 ( 335) 620 140.1 7.1e-33 NP_000507 (OMIM: 102200,103580,139320,166350,17480 ( 394) 620 140.1 8e-33 NP_536350 (OMIM: 102200,103580,139320,166350,17480 (1037) 620 140.4 1.7e-32 XP_016883305 (OMIM: 102200,103580,139320,166350,17 ( 320) 612 138.4 2.2e-32 >>NP_002063 (OMIM: 163000,185300,600998) guanine nucleot (359 aa) initn: 2361 init1: 2361 opt: 2361 Z-score: 2687.6 bits: 505.8 E(85289): 5.8e-143 Smith-Waterman score: 2361; 100.0% identity (100.0% similar) in 359 aa overlap (1-359:1-359) 10 20 30 40 50 60 pF1KB8 MTLESIMACCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MTLESIMACCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 IIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 IIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VSAFENPYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQDVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VSAFENPYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQDVL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 RVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 ESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQR 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 DAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV 310 320 330 340 350 >>NP_002058 (OMIM: 139313) guanine nucleotide-binding pr (359 aa) initn: 2159 init1: 2159 opt: 2159 Z-score: 2458.2 bits: 463.4 E(85289): 3.5e-130 Smith-Waterman score: 2159; 90.3% identity (98.3% similar) in 359 aa overlap (1-359:1-359) 10 20 30 40 50 60 pF1KB8 MTLESIMACCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMR :::::.::::::.:.::..::: :::.::::::::::::::::::::::::::::::::: NP_002 MTLESMMACCLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 IIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEK ::::.:::.:::::::::::::::::::::::::.:::: ::::.:::.: :.::::::: NP_002 IIHGAGYSEEDKRGFTKLVYQNIFTAMQAMIRAMETLKILYKYEQNKANALLIREVDVEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VSAFENPYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQDVL :..::. ::.:::.::.:::::::::::::::::::.::::.:.::.: .::::::::: NP_002 VTTFEHQYVSAIKTLWEDPGIQECYDRRREYQLSDSAKYYLTDVDRIATLGYLPTQQDVL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 RVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLV ::::::::::::::::...::::::::::::::::::::::::::::::::::::::::: NP_002 RVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 ESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQR ::::::::::::::::::::::::::::::::::::::::.::.::::::::::.::::: NP_002 ESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILYSHLVDYFPEFDGPQR 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 DAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV 310 320 330 340 350 >>XP_016870117 (OMIM: 163000,185300,600998) PREDICTED: g (301 aa) initn: 1995 init1: 1995 opt: 1995 Z-score: 2273.1 bits: 428.9 E(85289): 7.1e-120 Smith-Waterman score: 1995; 100.0% identity (100.0% similar) in 301 aa overlap (59-359:1-301) 30 40 50 60 70 80 pF1KB8 LRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGFTKLVYQNIFTAMQ :::::::::::::::::::::::::::::: XP_016 MRIIHGSGYSDEDKRGFTKLVYQNIFTAMQ 10 20 30 90 100 110 120 130 140 pF1KB8 AMIRAMDTLKIPYKYEHNKAHAQLVREVDVEKVSAFENPYVDAIKSLWNDPGIQECYDRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AMIRAMDTLKIPYKYEHNKAHAQLVREVDVEKVSAFENPYVDAIKSLWNDPGIQECYDRR 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB8 REYQLSDSTKYYLNDLDRVADPAYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFRMVDVGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REYQLSDSTKYYLNDLDRVADPAYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFRMVDVGG 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB8 QRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSS 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB8 VILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHF 220 230 240 250 260 270 330 340 350 pF1KB8 TCATDTENIRFVFAAVKDTILQLNLKEYNLV ::::::::::::::::::::::::::::::: XP_016 TCATDTENIRFVFAAVKDTILQLNLKEYNLV 280 290 300 >>NP_004288 (OMIM: 604397) guanine nucleotide-binding pr (355 aa) initn: 1956 init1: 1956 opt: 1956 Z-score: 2227.8 bits: 420.8 E(85289): 2.4e-117 Smith-Waterman score: 1956; 81.8% identity (94.9% similar) in 351 aa overlap (9-359:5-355) 10 20 30 40 50 60 pF1KB8 MTLESIMACCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMR :::: : ::..::. ::::::::::.:::::::::::::::::::::::::: NP_004 MAGCCCLSAEEKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMR 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 IIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEK :::::::::::..::::::::::::::::::::::::.: : :.:: .::..:::.:.: NP_004 IIHGSGYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTLRIQYVCEQNKENAQIIREVEVDK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB8 VSAFENPYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQDVL :: . :.:::.::.:::::::::::::::::::.::::.:.::.: :...::::::: NP_004 VSMLSREQVEAIKQLWQDPGIQECYDRRREYQLSDSAKYYLTDIDRIATPSFVPTQQDVL 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB8 RVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLV ::::::::::::::::...::::::::::::::::::::::.::::.::::::::::::. NP_004 RVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLA 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB8 ESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQR : :::::::::::::.:::::::: :::::::::::::::::::::::..::::: ::.. NP_004 ECDNENRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQ 240 250 260 270 280 290 310 320 330 340 350 pF1KB8 DAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV :..:::.::::.. : :::..:.:::::::::::.::::::::::::::::::.:.::: NP_004 DVRAARDFILKLYQDQNPDKEKVIYSHFTCATDTDNIRFVFAAVKDTILQLNLREFNLV 300 310 320 330 340 350 >>XP_016870830 (OMIM: 604397) PREDICTED: guanine nucleot (301 aa) initn: 1678 init1: 1678 opt: 1678 Z-score: 1913.1 bits: 362.3 E(85289): 8e-100 Smith-Waterman score: 1678; 81.1% identity (95.0% similar) in 301 aa overlap (59-359:1-301) 30 40 50 60 70 80 pF1KB8 LRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGFTKLVYQNIFTAMQ :::::::::::::..::::::::::::::: XP_016 MRIIHGSGYSDEDRKGFTKLVYQNIFTAMQ 10 20 30 90 100 110 120 130 140 pF1KB8 AMIRAMDTLKIPYKYEHNKAHAQLVREVDVEKVSAFENPYVDAIKSLWNDPGIQECYDRR :::::::::.: : :.:: .::..:::.:.::: . :.:::.::.::::::::::: XP_016 AMIRAMDTLRIQYVCEQNKENAQIIREVEVDKVSMLSREQVEAIKQLWQDPGIQECYDRR 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB8 REYQLSDSTKYYLNDLDRVADPAYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFRMVDVGG ::::::::.::::.:.::.: :...:::::::::::::::::::::::...::::::::: XP_016 REYQLSDSAKYYLTDIDRIATPSFVPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGG 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB8 QRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSS :::::::::::::.::::.::::::::::::.: :::::::::::::.:::::::: ::: XP_016 QRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIITYPWFLNSS 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB8 VILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHF ::::::::::::::::::::..::::: ::..:..:::.::::.. : :::..:.::::: XP_016 VILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVRAARDFILKLYQDQNPDKEKVIYSHF 220 230 240 250 260 270 330 340 350 pF1KB8 TCATDTENIRFVFAAVKDTILQLNLKEYNLV ::::::.::::::::::::::::::.:.::: XP_016 TCATDTDNIRFVFAAVKDTILQLNLREFNLV 280 290 300 >>XP_011517526 (OMIM: 604397) PREDICTED: guanine nucleot (237 aa) initn: 1346 init1: 1346 opt: 1346 Z-score: 1537.6 bits: 292.5 E(85289): 6.6e-79 Smith-Waterman score: 1346; 83.5% identity (97.4% similar) in 231 aa overlap (129-359:7-237) 100 110 120 130 140 150 pF1KB8 IPYKYEHNKAHAQLVREVDVEKVSAFENPYVDAIKSLWNDPGIQECYDRRREYQLSDSTK :.:::.::.:::::::::::::::::::.: XP_011 MLSREQVEAIKQLWQDPGIQECYDRRREYQLSDSAK 10 20 30 160 170 180 190 200 210 pF1KB8 YYLNDLDRVADPAYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIH :::.:.::.: :...:::::::::::::::::::::::...::::::::::::::::::: XP_011 YYLTDIDRIATPSFVPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIH 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB8 CFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDL :::.::::.::::::::::::.: :::::::::::::.:::::::: ::::::::::::: XP_011 CFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIITYPWFLNSSVILFLNKKDL 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB8 LEEKIMYSHLVDYFPEYDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIR ::::::::::..::::: ::..:..:::.::::.. : :::..:.:::::::::::.::: XP_011 LEEKIMYSHLISYFPEYTGPKQDVRAARDFILKLYQDQNPDKEKVIYSHFTCATDTDNIR 160 170 180 190 200 210 340 350 pF1KB8 FVFAAVKDTILQLNLKEYNLV :::::::::::::::.:.::: XP_011 FVFAAVKDTILQLNLREFNLV 220 230 >>NP_002059 (OMIM: 139314) guanine nucleotide-binding pr (374 aa) initn: 1345 init1: 1229 opt: 1229 Z-score: 1402.1 bits: 268.0 E(85289): 2.3e-71 Smith-Waterman score: 1336; 55.8% identity (80.9% similar) in 362 aa overlap (10-359:13-374) 10 20 30 40 50 pF1KB8 MTLESIMACCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIK ::.:. : : :...::.: : ..:.. : :::::::: :::::::::: NP_002 MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 QMRIIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVD :::::::.:::.:...:: :::::::..:.:::.::. :.::.. ..: ::.:: : NP_002 QMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQD 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 VEKVSAFENPYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQ ::..::. :. :.. :: : ::. ::.::::..: ::. :::. :.:... .:.:: : NP_002 PYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQ 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 DVLRVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQ :::: :.::::: :: :..:.. .:.::::::.:::.::::::::: ....:..:::::: NP_002 DVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQ 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB8 VLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDG : :...::::.:: ::: ::. :::...:::::::: :.::::: :::. ::: ..: NP_002 CLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQG 250 260 270 280 290 300 300 310 320 330 340 pF1KB8 PQRDAQAAREFILKMFVDL------NPDSDKI------IYSHFTCATDTENIRFVFAAVK :..::.::..::: :.. . .:...: ..::.::::::.::: :: :. NP_002 PKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVR 310 320 330 340 350 360 350 pF1KB8 DTILQLNLKEYNLV :..: : : ::. NP_002 DSVLARYLDEINLL 370 >>NP_002060 (OMIM: 139310) guanine nucleotide-binding pr (354 aa) initn: 1136 init1: 849 opt: 1166 Z-score: 1330.8 bits: 254.8 E(85289): 2.2e-67 Smith-Waterman score: 1166; 53.4% identity (76.8% similar) in 358 aa overlap (7-358:1-353) 10 20 30 40 50 60 pF1KB8 MTLESIMACCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMR :.: :: : : : . . :.:.::.: . : ::.::::::.:::::::..:::. NP_002 MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMK 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 IIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEK ::: .:::.:. . . .::.: . .. :.:::: ::: . ..:.:. .:.. : NP_002 IIHEAGYSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFG---DSARADDARQLFVL- 60 70 80 90 100 110 130 140 150 160 170 pF1KB8 VSAFENPYVDA-----IKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPT ..: :. .. : :: ::.: :.: :..: :::::.::. ::::::::.:.: :.:: NP_002 AGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPT 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 QQDVLRVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEY ::::::.:: ::::.: : .... :.: :::::::::.:::::::.::.:.: ::::.: NP_002 QQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDY 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 DQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEY : ::.:... :::.:: :: .: . :: ..:.:::::::::.:::: : :. .::: NP_002 DLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEY 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 DGPQRDAQAAREFILKMFVDLNPDSD-KIIYSHFTCATDTENIRFVFAAVKDTILQLNLK : . .:: .: .: ::: .: : ::.::::::::.:..::: :: :.:.. ::: NP_002 AGSNTYEEAA-AYIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLK 300 310 320 330 340 pF1KB8 EYNLV . .: NP_002 DCGLF 350 >>NP_006487 (OMIM: 139370,602483) guanine nucleotide-bin (354 aa) initn: 1113 init1: 837 opt: 1144 Z-score: 1305.9 bits: 250.2 E(85289): 5.3e-66 Smith-Waterman score: 1144; 52.9% identity (76.2% similar) in 357 aa overlap (7-358:1-353) 10 20 30 40 50 60 pF1KB8 MTLESIMACCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMR :.: :: : : : . . :.:.::.: . : .:.::::::.:::::::..:::. NP_006 MGCTLSAEDKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMK 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 IIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEK ::: .:::... . . .::.: . .. :.:::: ::: . . :.:. .:.. : NP_006 IIHEDGYSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFG---EAARADDARQLFVLA 60 70 80 90 100 110 130 140 150 160 170 pF1KB8 VSAFEN---PYV-DAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQ :: :. : . .:: :: : :.: :..: :::::.::..::::::::... :.::: NP_006 GSAEEGVMTPELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQ 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 QDVLRVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYD :::::.:: ::::.: : .... :.: :::::::::.:::::::.::.:.: ::::.:: NP_006 QDVLRTRVKTTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYD 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 QVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYD ::.:... :::.:: :: .: . :: ..:.:::::::::.:::: : :. .::: NP_006 LVLAEDEEMNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTICYPEYT 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 GPQRDAQAAREFILKMFVDLNPDSD-KIIYSHFTCATDTENIRFVFAAVKDTILQLNLKE : . .:: .: .: ::: .: : ::.::::::::.:..::: :: :.:.. :::: NP_006 GSNTYEEAA-AYIQCQFEDLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKE 300 310 320 330 340 350 pF1KB8 YNLV .: NP_006 CGLY >>NP_620073 (OMIM: 139311,615473) guanine nucleotide-bin (354 aa) initn: 1113 init1: 709 opt: 1143 Z-score: 1304.7 bits: 250.0 E(85289): 6.2e-66 Smith-Waterman score: 1143; 51.1% identity (76.0% similar) in 350 aa overlap (7-354:1-349) 10 20 30 40 50 60 pF1KB8 MTLESIMACCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMR :.: :: : . : . . ::..:..: .: ...::::::.:::::::..:::. NP_620 MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMK 10 20 30 40 50 70 80 90 100 110 pF1KB8 IIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREV--DV ::: .:.: :: . . .::.: . .. :..:::::: : : .. :: :..: .: . NP_620 IIHEDGFSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRM 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 EKVSAFENPYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQD : . : ..:. ::.: :::::..: :::::.::.::::..:::.. : ::.:: NP_620 EDTEPFSAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQD 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 VLRVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQV .::.:: ::::.: : .... ::. :::::::::.:::::::.::.:.: :::: :::: NP_620 ILRTRVKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQV 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 LVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGP : :... :::.:: :: .: . :: ..:.::::::::..:::: : :. :::: :: NP_620 LHEDETTNRMHESLKLFDSICNNKWFTDTSIILFLNKKDIFEEKIKKSPLTICFPEYTGP 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 QRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNL . ..:. .: .. . : .. : ::.: ::::::.::.::: :: :.:. ::. NP_620 SAFTEAV-AYIQAQYESKNKSAHKEIYTHVTCATDTNNIQFVFDAVTDVIIAKNLRGCGL 300 310 320 330 340 350 pF1KB8 V NP_620 Y 359 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:53:54 2016 done: Fri Nov 4 12:53:56 2016 Total Scan time: 7.550 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]