FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8437, 526 aa 1>>>pF1KB8437 526 - 526 aa - 526 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5170+/-0.000387; mu= 12.7463+/- 0.024 mean_var=109.9076+/-22.674, 0's: 0 Z-trim(115.3): 333 B-trim: 69 in 1/54 Lambda= 0.122338 statistics sampled from 25255 (25675) to 25255 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.671), E-opt: 0.2 (0.301), width: 16 Scan time: 10.710 The best scores are: opt bits E(85289) NP_062455 (OMIM: 612115) rho guanine nucleotide ex ( 526) 3503 629.5 7.7e-180 XP_011532068 (OMIM: 612115) PREDICTED: rho guanine ( 527) 3295 592.7 8.7e-169 XP_011532067 (OMIM: 612115) PREDICTED: rho guanine ( 527) 3295 592.7 8.7e-169 NP_001276627 (OMIM: 612115) rho guanine nucleotide ( 532) 3295 592.7 8.8e-169 XP_016861991 (OMIM: 612115) PREDICTED: rho guanine ( 538) 3295 592.7 8.9e-169 XP_011532066 (OMIM: 612115) PREDICTED: rho guanine ( 544) 3295 592.8 8.9e-169 NP_001122087 (OMIM: 612115) rho guanine nucleotide ( 558) 3295 592.8 9.1e-169 XP_005265244 (OMIM: 612115) PREDICTED: rho guanine ( 558) 3295 592.8 9.1e-169 XP_005265243 (OMIM: 612115) PREDICTED: rho guanine ( 558) 3295 592.8 9.1e-169 NP_001122088 (OMIM: 612115) rho guanine nucleotide ( 532) 3292 592.2 1.3e-168 XP_011532069 (OMIM: 612115) PREDICTED: rho guanine ( 412) 2742 495.1 1.7e-139 XP_016861994 (OMIM: 612115) PREDICTED: rho guanine ( 451) 2622 473.9 4.4e-133 XP_016861993 (OMIM: 612115) PREDICTED: rho guanine ( 463) 2414 437.2 5.1e-122 XP_016861992 (OMIM: 612115) PREDICTED: rho guanine ( 483) 2414 437.2 5.2e-122 XP_016861995 (OMIM: 612115) PREDICTED: rho guanine ( 457) 2411 436.7 7.2e-122 NP_005854 (OMIM: 606450) neuroepithelial cell-tran ( 542) 1882 343.4 1.1e-93 NP_001040625 (OMIM: 606450) neuroepithelial cell-t ( 596) 1873 341.8 3.4e-93 XP_016883926 (OMIM: 602442) PREDICTED: intersectin (1185) 389 80.1 4.2e-14 XP_016883925 (OMIM: 602442) PREDICTED: intersectin (1608) 389 80.2 5.3e-14 XP_016883924 (OMIM: 602442) PREDICTED: intersectin (1613) 389 80.2 5.3e-14 XP_016883923 (OMIM: 602442) PREDICTED: intersectin (1645) 389 80.2 5.4e-14 XP_016883922 (OMIM: 602442) PREDICTED: intersectin (1650) 389 80.2 5.4e-14 XP_016883919 (OMIM: 602442) PREDICTED: intersectin (1679) 389 80.2 5.5e-14 XP_016883918 (OMIM: 602442) PREDICTED: intersectin (1684) 389 80.2 5.5e-14 NP_001317939 (OMIM: 602442) intersectin-1 isoform (1716) 389 80.2 5.6e-14 NP_003015 (OMIM: 602442) intersectin-1 isoform ITS (1721) 389 80.2 5.6e-14 XP_016883917 (OMIM: 602442) PREDICTED: intersectin (1721) 389 80.2 5.6e-14 NP_062541 (OMIM: 604464) intersectin-2 isoform 3 [ (1670) 342 71.9 1.7e-11 NP_006268 (OMIM: 604464) intersectin-2 isoform 1 [ (1697) 342 71.9 1.7e-11 XP_011529194 (OMIM: 300429,300607) PREDICTED: rho ( 456) 285 61.4 6.5e-09 NP_001166950 (OMIM: 300429,300607) rho guanine nuc ( 463) 285 61.5 6.6e-09 XP_005262308 (OMIM: 300429,300607) PREDICTED: rho ( 495) 285 61.5 7e-09 NP_001317424 (OMIM: 300429,300607) rho guanine nuc ( 495) 285 61.5 7e-09 XP_016884857 (OMIM: 300429,300607) PREDICTED: rho ( 495) 285 61.5 7e-09 XP_016884856 (OMIM: 300429,300607) PREDICTED: rho ( 495) 285 61.5 7e-09 XP_005262307 (OMIM: 300429,300607) PREDICTED: rho ( 495) 285 61.5 7e-09 NP_056000 (OMIM: 300429,300607) rho guanine nucleo ( 516) 285 61.5 7.2e-09 XP_011529192 (OMIM: 300429,300607) PREDICTED: rho ( 516) 285 61.5 7.2e-09 XP_016884855 (OMIM: 300429,300607) PREDICTED: rho ( 516) 285 61.5 7.2e-09 XP_016884854 (OMIM: 300429,300607) PREDICTED: rho ( 516) 285 61.5 7.2e-09 XP_016884852 (OMIM: 300429,300607) PREDICTED: rho ( 521) 285 61.5 7.2e-09 XP_016884853 (OMIM: 300429,300607) PREDICTED: rho ( 521) 285 61.5 7.2e-09 XP_005262306 (OMIM: 300429,300607) PREDICTED: rho ( 523) 285 61.5 7.3e-09 XP_011508491 (OMIM: 605708) PREDICTED: rho guanine ( 945) 287 62.0 9.1e-09 XP_016883921 (OMIM: 602442) PREDICTED: intersectin (1660) 290 62.7 9.9e-09 XP_016883920 (OMIM: 602442) PREDICTED: intersectin (1665) 290 62.7 9.9e-09 XP_005245690 (OMIM: 605708) PREDICTED: rho guanine (1141) 287 62.1 1.1e-08 XP_011508489 (OMIM: 605708) PREDICTED: rho guanine (1485) 287 62.1 1.3e-08 NP_055599 (OMIM: 605708) rho guanine nucleotide ex (1522) 287 62.2 1.3e-08 XP_016858413 (OMIM: 605708) PREDICTED: rho guanine (1523) 287 62.2 1.3e-08 >>NP_062455 (OMIM: 612115) rho guanine nucleotide exchan (526 aa) initn: 3503 init1: 3503 opt: 3503 Z-score: 3349.6 bits: 629.5 E(85289): 7.7e-180 Smith-Waterman score: 3503; 100.0% identity (100.0% similar) in 526 aa overlap (1-526:1-526) 10 20 30 40 50 60 pF1KB8 MVAKDYPFYLTVKRANCSLELPPASGPAKDAEEPSNKRVKPLSRVTSLANLIPPVKATPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 MVAKDYPFYLTVKRANCSLELPPASGPAKDAEEPSNKRVKPLSRVTSLANLIPPVKATPL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KRFSQTLQRSISFRSESRPDILAPRPWSRNAAPSSTKRRDSKLWSETFDVCVNQMLTSKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 KRFSQTLQRSISFRSESRPDILAPRPWSRNAAPSSTKRRDSKLWSETFDVCVNQMLTSKE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 IKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELNQIFGTLDSLIPLHEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 IKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELNQIFGTLDSLIPLHEEL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQVAAKALLDHKKQDHRVQDFLQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 LSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQVAAKALLDHKKQDHRVQDFLQR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 CLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNPDQQHLEEAINIIQGIVAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 CLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNPDQQHLEEAINIIQGIVAE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 INTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELKNNRGVKLHVFLFQEVLVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 INTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELKNNRGVKLHVFLFQEVLVI 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TRAVTHNEQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRGAFSNNERIKNFFRVSFKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 TRAVTHNEQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRGAFSNNERIKNFFRVSFKN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 GSQSQTHSLQANDTFNKQQWLNCIRQAKETVLCAAGQAGVLDSEGSFLNPTTGSRELQGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_062 GSQSQTHSLQANDTFNKQQWLNCIRQAKETVLCAAGQAGVLDSEGSFLNPTTGSRELQGE 430 440 450 460 470 480 490 500 510 520 pF1KB8 TKLEQMDQSDSESDCSMDTSEVSLDCERMEQTDSSCGNSRHGESNV :::::::::::::::::::::::::::::::::::::::::::::: NP_062 TKLEQMDQSDSESDCSMDTSEVSLDCERMEQTDSSCGNSRHGESNV 490 500 510 520 >>XP_011532068 (OMIM: 612115) PREDICTED: rho guanine nuc (527 aa) initn: 3295 init1: 3295 opt: 3295 Z-score: 3151.2 bits: 592.7 E(85289): 8.7e-169 Smith-Waterman score: 3295; 96.9% identity (97.9% similar) in 514 aa overlap (13-526:14-527) 10 20 30 40 50 pF1KB8 MVAKDYPFYLTVKRANCSLELPPASGPAKDAEEPSNKRVKPLSRVTSLANLIPPVKATP :: . . . .: . : ::::::::::::::::::::::::::: XP_011 MFPSPKAWNFRGRKRKQSTQDEDAVSLCSLDISEPSNKRVKPLSRVTSLANLIPPVKATP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 LKRFSQTLQRSISFRSESRPDILAPRPWSRNAAPSSTKRRDSKLWSETFDVCVNQMLTSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKRFSQTLQRSISFRSESRPDILAPRPWSRNAAPSSTKRRDSKLWSETFDVCVNQMLTSK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 EIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELNQIFGTLDSLIPLHEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELNQIFGTLDSLIPLHEE 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 LLSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQVAAKALLDHKKQDHRVQDFLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQVAAKALLDHKKQDHRVQDFLQ 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB8 RCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNPDQQHLEEAINIIQGIVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNPDQQHLEEAINIIQGIVA 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB8 EINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELKNNRGVKLHVFLFQEVLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELKNNRGVKLHVFLFQEVLV 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB8 ITRAVTHNEQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRGAFSNNERIKNFFRVSFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ITRAVTHNEQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRGAFSNNERIKNFFRVSFK 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB8 NGSQSQTHSLQANDTFNKQQWLNCIRQAKETVLCAAGQAGVLDSEGSFLNPTTGSRELQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGSQSQTHSLQANDTFNKQQWLNCIRQAKETVLCAAGQAGVLDSEGSFLNPTTGSRELQG 430 440 450 460 470 480 480 490 500 510 520 pF1KB8 ETKLEQMDQSDSESDCSMDTSEVSLDCERMEQTDSSCGNSRHGESNV ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETKLEQMDQSDSESDCSMDTSEVSLDCERMEQTDSSCGNSRHGESNV 490 500 510 520 >>XP_011532067 (OMIM: 612115) PREDICTED: rho guanine nuc (527 aa) initn: 3295 init1: 3295 opt: 3295 Z-score: 3151.2 bits: 592.7 E(85289): 8.7e-169 Smith-Waterman score: 3295; 96.9% identity (97.9% similar) in 514 aa overlap (13-526:14-527) 10 20 30 40 50 pF1KB8 MVAKDYPFYLTVKRANCSLELPPASGPAKDAEEPSNKRVKPLSRVTSLANLIPPVKATP :: . . . .: . : ::::::::::::::::::::::::::: XP_011 MFPSPKAWNFRGRKRKQSTQDEDAVSLCSLDISEPSNKRVKPLSRVTSLANLIPPVKATP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 LKRFSQTLQRSISFRSESRPDILAPRPWSRNAAPSSTKRRDSKLWSETFDVCVNQMLTSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKRFSQTLQRSISFRSESRPDILAPRPWSRNAAPSSTKRRDSKLWSETFDVCVNQMLTSK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 EIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELNQIFGTLDSLIPLHEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELNQIFGTLDSLIPLHEE 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 LLSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQVAAKALLDHKKQDHRVQDFLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQVAAKALLDHKKQDHRVQDFLQ 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB8 RCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNPDQQHLEEAINIIQGIVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNPDQQHLEEAINIIQGIVA 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB8 EINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELKNNRGVKLHVFLFQEVLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELKNNRGVKLHVFLFQEVLV 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB8 ITRAVTHNEQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRGAFSNNERIKNFFRVSFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ITRAVTHNEQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRGAFSNNERIKNFFRVSFK 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB8 NGSQSQTHSLQANDTFNKQQWLNCIRQAKETVLCAAGQAGVLDSEGSFLNPTTGSRELQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGSQSQTHSLQANDTFNKQQWLNCIRQAKETVLCAAGQAGVLDSEGSFLNPTTGSRELQG 430 440 450 460 470 480 480 490 500 510 520 pF1KB8 ETKLEQMDQSDSESDCSMDTSEVSLDCERMEQTDSSCGNSRHGESNV ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETKLEQMDQSDSESDCSMDTSEVSLDCERMEQTDSSCGNSRHGESNV 490 500 510 520 >>NP_001276627 (OMIM: 612115) rho guanine nucleotide exc (532 aa) initn: 3295 init1: 3295 opt: 3295 Z-score: 3151.2 bits: 592.7 E(85289): 8.8e-169 Smith-Waterman score: 3295; 96.9% identity (97.9% similar) in 514 aa overlap (13-526:19-532) 10 20 30 40 50 pF1KB8 MVAKDYPFYLTVKRANCSLELPPASGPAKDAEEPSNKRVKPLSRVTSLANLIPP :: . . . .: . : :::::::::::::::::::::: NP_001 MRSERPMVWCCLFVRSQRKRKQSTQDEDAVSLCSLDISEPSNKRVKPLSRVTSLANLIPP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 VKATPLKRFSQTLQRSISFRSESRPDILAPRPWSRNAAPSSTKRRDSKLWSETFDVCVNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKATPLKRFSQTLQRSISFRSESRPDILAPRPWSRNAAPSSTKRRDSKLWSETFDVCVNQ 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 MLTSKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELNQIFGTLDSLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLTSKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELNQIFGTLDSLI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 PLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQVAAKALLDHKKQDHRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQVAAKALLDHKKQDHRV 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB8 QDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNPDQQHLEEAINII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNPDQQHLEEAINII 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB8 QGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELKNNRGVKLHVFLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELKNNRGVKLHVFLF 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB8 QEVLVITRAVTHNEQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRGAFSNNERIKNFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEVLVITRAVTHNEQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRGAFSNNERIKNFF 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB8 RVSFKNGSQSQTHSLQANDTFNKQQWLNCIRQAKETVLCAAGQAGVLDSEGSFLNPTTGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RVSFKNGSQSQTHSLQANDTFNKQQWLNCIRQAKETVLCAAGQAGVLDSEGSFLNPTTGS 430 440 450 460 470 480 480 490 500 510 520 pF1KB8 RELQGETKLEQMDQSDSESDCSMDTSEVSLDCERMEQTDSSCGNSRHGESNV :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RELQGETKLEQMDQSDSESDCSMDTSEVSLDCERMEQTDSSCGNSRHGESNV 490 500 510 520 530 >>XP_016861991 (OMIM: 612115) PREDICTED: rho guanine nuc (538 aa) initn: 3295 init1: 3295 opt: 3295 Z-score: 3151.1 bits: 592.7 E(85289): 8.9e-169 Smith-Waterman score: 3295; 96.9% identity (97.9% similar) in 514 aa overlap (13-526:25-538) 10 20 30 40 pF1KB8 MVAKDYPFYLTVKRANCSLELPPASGPAKDAEEPSNKRVKPLSRVTSL :: . . . .: . : :::::::::::::::: XP_016 MPKRQRQNNFPMFPSPKAWNFRGRKRKQSTQDEDAVSLCSLDISEPSNKRVKPLSRVTSL 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 ANLIPPVKATPLKRFSQTLQRSISFRSESRPDILAPRPWSRNAAPSSTKRRDSKLWSETF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ANLIPPVKATPLKRFSQTLQRSISFRSESRPDILAPRPWSRNAAPSSTKRRDSKLWSETF 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 DVCVNQMLTSKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELNQIFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVCVNQMLTSKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELNQIFG 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB8 TLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQVAAKALLDHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQVAAKALLDHK 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB8 KQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNPDQQHLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNPDQQHLE 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB8 EAINIIQGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELKNNRGVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAINIIQGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELKNNRGVK 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB8 LHVFLFQEVLVITRAVTHNEQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRGAFSNNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHVFLFQEVLVITRAVTHNEQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRGAFSNNE 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB8 RIKNFFRVSFKNGSQSQTHSLQANDTFNKQQWLNCIRQAKETVLCAAGQAGVLDSEGSFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RIKNFFRVSFKNGSQSQTHSLQANDTFNKQQWLNCIRQAKETVLCAAGQAGVLDSEGSFL 430 440 450 460 470 480 470 480 490 500 510 520 pF1KB8 NPTTGSRELQGETKLEQMDQSDSESDCSMDTSEVSLDCERMEQTDSSCGNSRHGESNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NPTTGSRELQGETKLEQMDQSDSESDCSMDTSEVSLDCERMEQTDSSCGNSRHGESNV 490 500 510 520 530 >>XP_011532066 (OMIM: 612115) PREDICTED: rho guanine nuc (544 aa) initn: 3295 init1: 3295 opt: 3295 Z-score: 3151.0 bits: 592.8 E(85289): 8.9e-169 Smith-Waterman score: 3295; 96.9% identity (97.9% similar) in 514 aa overlap (13-526:31-544) 10 20 30 40 pF1KB8 MVAKDYPFYLTVKRANCSLELPPASGPAKDAEEPSNKRVKPL :: . . . .: . : :::::::::: XP_011 MFDRNIWPKRQRQNNFPMFPSPKAWNFRGRKRKQSTQDEDAVSLCSLDISEPSNKRVKPL 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB8 SRVTSLANLIPPVKATPLKRFSQTLQRSISFRSESRPDILAPRPWSRNAAPSSTKRRDSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRVTSLANLIPPVKATPLKRFSQTLQRSISFRSESRPDILAPRPWSRNAAPSSTKRRDSK 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB8 LWSETFDVCVNQMLTSKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LWSETFDVCVNQMLTSKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB8 LNQIFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQVAAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LNQIFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQVAAK 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB8 ALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNP 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB8 DQQHLEEAINIIQGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQQHLEEAINIIQGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELK 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB8 NNRGVKLHVFLFQEVLVITRAVTHNEQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NNRGVKLHVFLFQEVLVITRAVTHNEQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRG 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB8 AFSNNERIKNFFRVSFKNGSQSQTHSLQANDTFNKQQWLNCIRQAKETVLCAAGQAGVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AFSNNERIKNFFRVSFKNGSQSQTHSLQANDTFNKQQWLNCIRQAKETVLCAAGQAGVLD 430 440 450 460 470 480 470 480 490 500 510 520 pF1KB8 SEGSFLNPTTGSRELQGETKLEQMDQSDSESDCSMDTSEVSLDCERMEQTDSSCGNSRHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SEGSFLNPTTGSRELQGETKLEQMDQSDSESDCSMDTSEVSLDCERMEQTDSSCGNSRHG 490 500 510 520 530 540 pF1KB8 ESNV :::: XP_011 ESNV >>NP_001122087 (OMIM: 612115) rho guanine nucleotide exc (558 aa) initn: 3295 init1: 3295 opt: 3295 Z-score: 3150.9 bits: 592.8 E(85289): 9.1e-169 Smith-Waterman score: 3295; 96.9% identity (97.9% similar) in 514 aa overlap (13-526:45-558) 10 20 30 40 pF1KB8 MVAKDYPFYLTVKRANCSLELPPASGPAKDAEEPSNKRVKPL :: . . . .: . : :::::::::: NP_001 MEENKERPKRQRQNNFPMFPSPKAWNFRGRKRKQSTQDEDAVSLCSLDISEPSNKRVKPL 20 30 40 50 60 70 50 60 70 80 90 100 pF1KB8 SRVTSLANLIPPVKATPLKRFSQTLQRSISFRSESRPDILAPRPWSRNAAPSSTKRRDSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRVTSLANLIPPVKATPLKRFSQTLQRSISFRSESRPDILAPRPWSRNAAPSSTKRRDSK 80 90 100 110 120 130 110 120 130 140 150 160 pF1KB8 LWSETFDVCVNQMLTSKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LWSETFDVCVNQMLTSKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQE 140 150 160 170 180 190 170 180 190 200 210 220 pF1KB8 LNQIFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQVAAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LNQIFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQVAAK 200 210 220 230 240 250 230 240 250 260 270 280 pF1KB8 ALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNP 260 270 280 290 300 310 290 300 310 320 330 340 pF1KB8 DQQHLEEAINIIQGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DQQHLEEAINIIQGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELK 320 330 340 350 360 370 350 360 370 380 390 400 pF1KB8 NNRGVKLHVFLFQEVLVITRAVTHNEQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNRGVKLHVFLFQEVLVITRAVTHNEQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRG 380 390 400 410 420 430 410 420 430 440 450 460 pF1KB8 AFSNNERIKNFFRVSFKNGSQSQTHSLQANDTFNKQQWLNCIRQAKETVLCAAGQAGVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AFSNNERIKNFFRVSFKNGSQSQTHSLQANDTFNKQQWLNCIRQAKETVLCAAGQAGVLD 440 450 460 470 480 490 470 480 490 500 510 520 pF1KB8 SEGSFLNPTTGSRELQGETKLEQMDQSDSESDCSMDTSEVSLDCERMEQTDSSCGNSRHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEGSFLNPTTGSRELQGETKLEQMDQSDSESDCSMDTSEVSLDCERMEQTDSSCGNSRHG 500 510 520 530 540 550 pF1KB8 ESNV :::: NP_001 ESNV >>XP_005265244 (OMIM: 612115) PREDICTED: rho guanine nuc (558 aa) initn: 3295 init1: 3295 opt: 3295 Z-score: 3150.9 bits: 592.8 E(85289): 9.1e-169 Smith-Waterman score: 3295; 96.9% identity (97.9% similar) in 514 aa overlap (13-526:45-558) 10 20 30 40 pF1KB8 MVAKDYPFYLTVKRANCSLELPPASGPAKDAEEPSNKRVKPL :: . . . .: . : :::::::::: XP_005 MEENKERPKRQRQNNFPMFPSPKAWNFRGRKRKQSTQDEDAVSLCSLDISEPSNKRVKPL 20 30 40 50 60 70 50 60 70 80 90 100 pF1KB8 SRVTSLANLIPPVKATPLKRFSQTLQRSISFRSESRPDILAPRPWSRNAAPSSTKRRDSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SRVTSLANLIPPVKATPLKRFSQTLQRSISFRSESRPDILAPRPWSRNAAPSSTKRRDSK 80 90 100 110 120 130 110 120 130 140 150 160 pF1KB8 LWSETFDVCVNQMLTSKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LWSETFDVCVNQMLTSKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQE 140 150 160 170 180 190 170 180 190 200 210 220 pF1KB8 LNQIFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQVAAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LNQIFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQVAAK 200 210 220 230 240 250 230 240 250 260 270 280 pF1KB8 ALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNP 260 270 280 290 300 310 290 300 310 320 330 340 pF1KB8 DQQHLEEAINIIQGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DQQHLEEAINIIQGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELK 320 330 340 350 360 370 350 360 370 380 390 400 pF1KB8 NNRGVKLHVFLFQEVLVITRAVTHNEQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NNRGVKLHVFLFQEVLVITRAVTHNEQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRG 380 390 400 410 420 430 410 420 430 440 450 460 pF1KB8 AFSNNERIKNFFRVSFKNGSQSQTHSLQANDTFNKQQWLNCIRQAKETVLCAAGQAGVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AFSNNERIKNFFRVSFKNGSQSQTHSLQANDTFNKQQWLNCIRQAKETVLCAAGQAGVLD 440 450 460 470 480 490 470 480 490 500 510 520 pF1KB8 SEGSFLNPTTGSRELQGETKLEQMDQSDSESDCSMDTSEVSLDCERMEQTDSSCGNSRHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SEGSFLNPTTGSRELQGETKLEQMDQSDSESDCSMDTSEVSLDCERMEQTDSSCGNSRHG 500 510 520 530 540 550 pF1KB8 ESNV :::: XP_005 ESNV >>XP_005265243 (OMIM: 612115) PREDICTED: rho guanine nuc (558 aa) initn: 3295 init1: 3295 opt: 3295 Z-score: 3150.9 bits: 592.8 E(85289): 9.1e-169 Smith-Waterman score: 3295; 96.9% identity (97.9% similar) in 514 aa overlap (13-526:45-558) 10 20 30 40 pF1KB8 MVAKDYPFYLTVKRANCSLELPPASGPAKDAEEPSNKRVKPL :: . . . .: . : :::::::::: XP_005 MEENKERPKRQRQNNFPMFPSPKAWNFRGRKRKQSTQDEDAVSLCSLDISEPSNKRVKPL 20 30 40 50 60 70 50 60 70 80 90 100 pF1KB8 SRVTSLANLIPPVKATPLKRFSQTLQRSISFRSESRPDILAPRPWSRNAAPSSTKRRDSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SRVTSLANLIPPVKATPLKRFSQTLQRSISFRSESRPDILAPRPWSRNAAPSSTKRRDSK 80 90 100 110 120 130 110 120 130 140 150 160 pF1KB8 LWSETFDVCVNQMLTSKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LWSETFDVCVNQMLTSKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQE 140 150 160 170 180 190 170 180 190 200 210 220 pF1KB8 LNQIFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQVAAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LNQIFGTLDSLIPLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQVAAK 200 210 220 230 240 250 230 240 250 260 270 280 pF1KB8 ALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNP 260 270 280 290 300 310 290 300 310 320 330 340 pF1KB8 DQQHLEEAINIIQGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DQQHLEEAINIIQGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELK 320 330 340 350 360 370 350 360 370 380 390 400 pF1KB8 NNRGVKLHVFLFQEVLVITRAVTHNEQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NNRGVKLHVFLFQEVLVITRAVTHNEQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRG 380 390 400 410 420 430 410 420 430 440 450 460 pF1KB8 AFSNNERIKNFFRVSFKNGSQSQTHSLQANDTFNKQQWLNCIRQAKETVLCAAGQAGVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AFSNNERIKNFFRVSFKNGSQSQTHSLQANDTFNKQQWLNCIRQAKETVLCAAGQAGVLD 440 450 460 470 480 490 470 480 490 500 510 520 pF1KB8 SEGSFLNPTTGSRELQGETKLEQMDQSDSESDCSMDTSEVSLDCERMEQTDSSCGNSRHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SEGSFLNPTTGSRELQGETKLEQMDQSDSESDCSMDTSEVSLDCERMEQTDSSCGNSRHG 500 510 520 530 540 550 pF1KB8 ESNV :::: XP_005 ESNV >>NP_001122088 (OMIM: 612115) rho guanine nucleotide exc (532 aa) initn: 3287 init1: 3287 opt: 3292 Z-score: 3148.3 bits: 592.2 E(85289): 1.3e-168 Smith-Waterman score: 3292; 97.3% identity (98.2% similar) in 510 aa overlap (17-526:23-532) 10 20 30 40 50 pF1KB8 MVAKDYPFYLTVKRANCSLELPPASGPAKDAEEPSNKRVKPLSRVTSLANLIPP : : .. . ..:::::::::::::::::::::: NP_001 MIEVCHHNWLLWLCPSKFGIFMCCLASTTGQMELRRTREPSNKRVKPLSRVTSLANLIPP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 VKATPLKRFSQTLQRSISFRSESRPDILAPRPWSRNAAPSSTKRRDSKLWSETFDVCVNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKATPLKRFSQTLQRSISFRSESRPDILAPRPWSRNAAPSSTKRRDSKLWSETFDVCVNQ 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 MLTSKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELNQIFGTLDSLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLTSKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQELNQIFGTLDSLI 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 PLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQVAAKALLDHKKQDHRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLHEELLSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQVAAKALLDHKKQDHRV 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB8 QDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNPDQQHLEEAINII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHTPNDNPDQQHLEEAINII 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB8 QGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELKNNRGVKLHVFLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVLCCHGELKNNRGVKLHVFLF 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB8 QEVLVITRAVTHNEQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRGAFSNNERIKNFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEVLVITRAVTHNEQLCYQLYRQPIPVKDLLLEDLQDGEVRLGGSLRGAFSNNERIKNFF 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB8 RVSFKNGSQSQTHSLQANDTFNKQQWLNCIRQAKETVLCAAGQAGVLDSEGSFLNPTTGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RVSFKNGSQSQTHSLQANDTFNKQQWLNCIRQAKETVLCAAGQAGVLDSEGSFLNPTTGS 430 440 450 460 470 480 480 490 500 510 520 pF1KB8 RELQGETKLEQMDQSDSESDCSMDTSEVSLDCERMEQTDSSCGNSRHGESNV :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RELQGETKLEQMDQSDSESDCSMDTSEVSLDCERMEQTDSSCGNSRHGESNV 490 500 510 520 530 526 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:54:37 2016 done: Fri Nov 4 12:54:39 2016 Total Scan time: 10.710 Total Display time: 0.120 Function used was FASTA [36.3.4 Apr, 2011]