Result of FASTA (omim) for
pF1KB8443
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8443, 586 aa
1>>>pF1KB8443 586 - 586 aa - 586 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.0427+/-0.000552; mu= -1.9894+/- 0.034
mean_var=550.0008+/-120.199, 0's: 0 Z-trim(118.6): 1848 B-trim: 0 in 0/57
Lambda= 0.054688
statistics sampled from 29337 (31742) to 29337 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.372), width: 16
Scan time: 9.950
The best scores are: opt bits E(85289)
NP_001005735 (OMIM: 114480,176807,259500,604373,60 ( 586) 3876 321.6 4.6e-87
XP_011528141 (OMIM: 114480,176807,259500,604373,60 ( 596) 3876 321.6 4.7e-87
XP_016884049 (OMIM: 114480,176807,259500,604373,60 ( 584) 2990 251.7 5.1e-66
NP_009125 (OMIM: 114480,176807,259500,604373,60926 ( 543) 2896 244.2 8.4e-64
XP_011528146 (OMIM: 114480,176807,259500,604373,60 ( 409) 2514 213.9 8.5e-55
XP_011528142 (OMIM: 114480,176807,259500,604373,60 ( 567) 2508 213.6 1.4e-54
NP_001244316 (OMIM: 114480,176807,259500,604373,60 ( 322) 2107 181.6 3.5e-45
XP_011528147 (OMIM: 114480,176807,259500,604373,60 ( 322) 2107 181.6 3.5e-45
XP_016884050 (OMIM: 114480,176807,259500,604373,60 ( 322) 2107 181.6 3.5e-45
XP_006724179 (OMIM: 114480,176807,259500,604373,60 ( 362) 2072 178.9 2.5e-44
XP_006724177 (OMIM: 114480,176807,259500,604373,60 ( 394) 2066 178.5 3.6e-44
XP_011528145 (OMIM: 114480,176807,259500,604373,60 ( 476) 2067 178.7 3.8e-44
XP_011528144 (OMIM: 114480,176807,259500,604373,60 ( 486) 2067 178.7 3.9e-44
XP_011528143 (OMIM: 114480,176807,259500,604373,60 ( 519) 2067 178.8 4e-44
NP_665861 (OMIM: 114480,176807,259500,604373,60926 ( 514) 1528 136.2 2.5e-31
NP_003647 (OMIM: 604998) calcium/calmodulin-depend ( 370) 737 73.6 1.3e-12
XP_005265573 (OMIM: 604998) PREDICTED: calcium/cal ( 413) 737 73.7 1.4e-12
XP_016857355 (OMIM: 614994) PREDICTED: calcium/cal ( 476) 731 73.3 2.1e-12
NP_065172 (OMIM: 614994) calcium/calmodulin-depend ( 476) 731 73.3 2.1e-12
XP_006717546 (OMIM: 607957) PREDICTED: calcium/cal ( 355) 723 72.5 2.7e-12
NP_065130 (OMIM: 607957) calcium/calmodulin-depend ( 357) 723 72.5 2.7e-12
XP_006717545 (OMIM: 607957) PREDICTED: calcium/cal ( 362) 723 72.5 2.7e-12
NP_705718 (OMIM: 607957) calcium/calmodulin-depend ( 385) 723 72.5 2.8e-12
XP_006717544 (OMIM: 607957) PREDICTED: calcium/cal ( 366) 716 71.9 4e-12
XP_011517893 (OMIM: 607957) PREDICTED: calcium/cal ( 372) 707 71.2 6.7e-12
NP_001310303 (OMIM: 114080) calcium/calmodulin-dep ( 473) 665 68.1 7.6e-11
NP_001735 (OMIM: 114080) calcium/calmodulin-depend ( 473) 665 68.1 7.6e-11
NP_001310304 (OMIM: 114080) calcium/calmodulin-dep ( 473) 665 68.1 7.6e-11
XP_011529412 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 660 67.5 8.3e-11
XP_011529414 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 660 67.5 8.3e-11
XP_011529413 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 660 67.5 8.3e-11
XP_016884768 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 660 67.5 8.3e-11
XP_006724872 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 660 67.5 8.3e-11
XP_016884767 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 660 67.5 8.3e-11
XP_011529409 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 660 67.5 8.3e-11
XP_005274708 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 660 67.5 8.3e-11
NP_001129212 (OMIM: 300680) calcium/calmodulin-dep ( 360) 660 67.5 8.6e-11
XP_011529410 (OMIM: 300680) PREDICTED: calcium/cal ( 361) 660 67.5 8.6e-11
XP_016884766 (OMIM: 300680) PREDICTED: calcium/cal ( 426) 660 67.6 9.4e-11
NP_001034671 (OMIM: 300680) calcium/calmodulin-dep ( 426) 660 67.6 9.4e-11
XP_016859232 (OMIM: 607077) PREDICTED: serine/thre ( 631) 651 67.2 1.9e-10
XP_016859233 (OMIM: 607077) PREDICTED: serine/thre ( 631) 651 67.2 1.9e-10
XP_016859230 (OMIM: 607077) PREDICTED: serine/thre ( 717) 651 67.2 2e-10
XP_016859231 (OMIM: 607077) PREDICTED: serine/thre ( 717) 651 67.2 2e-10
XP_005264295 (OMIM: 607077) PREDICTED: serine/thre ( 786) 651 67.3 2.1e-10
XP_016862843 (OMIM: 604998) PREDICTED: calcium/cal ( 326) 641 65.9 2.3e-10
NP_005804 (OMIM: 607077) serine/threonine-protein ( 890) 651 67.4 2.3e-10
XP_005264294 (OMIM: 607077) PREDICTED: serine/thre ( 890) 651 67.4 2.3e-10
XP_005265574 (OMIM: 604998) PREDICTED: calcium/cal ( 369) 641 66.0 2.5e-10
XP_016876951 (OMIM: 605435) PREDICTED: serine/thre ( 747) 648 67.0 2.5e-10
>>NP_001005735 (OMIM: 114480,176807,259500,604373,609265 (586 aa)
initn: 3876 init1: 3876 opt: 3876 Z-score: 1684.0 bits: 321.6 E(85289): 4.6e-87
Smith-Waterman score: 3876; 100.0% identity (100.0% similar) in 586 aa overlap (1-586:1-586)
10 20 30 40 50 60
pF1KB8 MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSSQSSHSSSGTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSSQSSHSSSGTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLETESGHVTQSDLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLETESGHVTQSDLEL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LLSSDPPASASQSAGIRGVRHHPRPVCSLKCVNDNYWFGRDKSCEYCFDEPLLKRTDKYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSSDPPASASQSAGIRGVRHHPRPVCSLKCVNDNYWFGRDKSCEYCFDEPLLKRTDKYR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 TYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIALSLSRNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIALSLSRNK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 IGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFDKVVGNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFDKVVGNK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 RLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 TSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 DQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQD
490 500 510 520 530 540
550 560 570 580
pF1KB8 LLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
550 560 570 580
>>XP_011528141 (OMIM: 114480,176807,259500,604373,609265 (596 aa)
initn: 3876 init1: 3876 opt: 3876 Z-score: 1683.9 bits: 321.6 E(85289): 4.7e-87
Smith-Waterman score: 3876; 100.0% identity (100.0% similar) in 586 aa overlap (1-586:11-596)
10 20 30 40 50
pF1KB8 MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSS
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLRLLTSMVVMSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 QSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLETES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLETES
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 GHVTQSDLELLLSSDPPASASQSAGIRGVRHHPRPVCSLKCVNDNYWFGRDKSCEYCFDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHVTQSDLELLLSSDPPASASQSAGIRGVRHHPRPVCSLKCVNDNYWFGRDKSCEYCFDE
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 PLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 EIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 IKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGG
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 ELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKIT
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB8 DFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPF
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB8 SEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQ
490 500 510 520 530 540
540 550 560 570 580
pF1KB8 DEDMKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEDMKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
550 560 570 580 590
>>XP_016884049 (OMIM: 114480,176807,259500,604373,609265 (584 aa)
initn: 3762 init1: 2890 opt: 2990 Z-score: 1306.2 bits: 251.7 E(85289): 5.1e-66
Smith-Waterman score: 3742; 97.8% identity (98.0% similar) in 586 aa overlap (1-586:11-584)
10 20 30 40 50
pF1KB8 MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSS
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLRLLTSMVVMSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 QSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLETES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLETES
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 GHVTQSDLELLLSSDPPASASQSAGIRGVRHHPRPVCSLKCVNDNYWFGRDKSCEYCFDE
::::::::::::::::::::::::::: .::::::::::::::::::::
XP_016 GHVTQSDLELLLSSDPPASASQSAGIR------------ECVNDNYWFGRDKSCEYCFDE
130 140 150 160
180 190 200 210 220 230
pF1KB8 PLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNS
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB8 EIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVA
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB8 IKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGG
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB8 ELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKIT
350 360 370 380 390 400
420 430 440 450 460 470
pF1KB8 DFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPF
410 420 430 440 450 460
480 490 500 510 520 530
pF1KB8 SEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQ
470 480 490 500 510 520
540 550 560 570 580
pF1KB8 DEDMKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEDMKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
530 540 550 560 570 580
>>NP_009125 (OMIM: 114480,176807,259500,604373,609265) s (543 aa)
initn: 2896 init1: 2896 opt: 2896 Z-score: 1266.4 bits: 244.2 E(85289): 8.4e-64
Smith-Waterman score: 3494; 92.7% identity (92.7% similar) in 586 aa overlap (1-586:1-543)
10 20 30 40 50 60
pF1KB8 MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSSQSSHSSSGTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSSQSSHSSSGTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLETESGHVTQSDLEL
:::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLE-------------
70 80 90 100
130 140 150 160 170 180
pF1KB8 LLSSDPPASASQSAGIRGVRHHPRPVCSLKCVNDNYWFGRDKSCEYCFDEPLLKRTDKYR
::::::::::::::::::::::::::::::
NP_009 ------------------------------CVNDNYWFGRDKSCEYCFDEPLLKRTDKYR
110 120 130
190 200 210 220 230 240
pF1KB8 TYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIALSLSRNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIALSLSRNK
140 150 160 170 180 190
250 260 270 280 290 300
pF1KB8 VFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 VFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFA
200 210 220 230 240 250
310 320 330 340 350 360
pF1KB8 IGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFDKVVGNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 IGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFDKVVGNK
260 270 280 290 300 310
370 380 390 400 410 420
pF1KB8 RLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 RLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGHSKILGE
320 330 340 350 360 370
430 440 450 460 470 480
pF1KB8 TSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHRTQVSLK
380 390 400 410 420 430
490 500 510 520 530 540
pF1KB8 DQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 DQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDMKRKFQD
440 450 460 470 480 490
550 560 570 580
pF1KB8 LLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
500 510 520 530 540
>>XP_011528146 (OMIM: 114480,176807,259500,604373,609265 (409 aa)
initn: 2624 init1: 2511 opt: 2514 Z-score: 1104.8 bits: 213.9 E(85289): 8.5e-55
Smith-Waterman score: 2514; 97.9% identity (99.0% similar) in 389 aa overlap (1-387:11-399)
10 20 30 40 50
pF1KB8 MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSS
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLRLLTSMVVMSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 QSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLETES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLETES
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 GHVTQSDLELLLSSDPPASASQSAGIRGVRHHPRPVCSLKCVNDNYWFGRDKSCEYCFDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHVTQSDLELLLSSDPPASASQSAGIRGVRHHPRPVCSLKCVNDNYWFGRDKSCEYCFDE
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 PLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 EIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 IKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGG
310 320 330 340 350 360
360 370 380 390 400
pF1KB8 ELFDKVVGNKRLKEATCKLYFYQMLLAVQY--LHENGIIHRDLKPENVLLSSQEEDCLIK
:::::::::::::::::::::::::::::. . :: ..
XP_011 ELFDKVVGNKRLKEATCKLYFYQMLLAVQFSMILENMVVCITAYGFTQL
370 380 390 400
410 420 430 440 450 460
pF1KB8 ITDFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYP
>>XP_011528142 (OMIM: 114480,176807,259500,604373,609265 (567 aa)
initn: 2507 init1: 2507 opt: 2508 Z-score: 1100.8 bits: 213.6 E(85289): 1.4e-54
Smith-Waterman score: 3614; 95.1% identity (95.1% similar) in 586 aa overlap (1-586:11-567)
10 20 30 40 50
pF1KB8 MSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSS
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLRLLTSMVVMSRESDVEAQQSHGSSACSQPHGSVTQSQGSSSQSQGISSSSTSTMPNSS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 QSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLETES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSSHSSSGTLSSLETVSTQELYSIPEDQEPEDQEPEEPTPAPWARLWALQDGFANLETES
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 GHVTQSDLELLLSSDPPASASQSAGIRGVRHHPRPVCSLKCVNDNYWFGRDKSCEYCFDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GHVTQSDLELLLSSDPPASASQSAGIRGVRHHPRPVCSLKCVNDNYWFGRDKSCEYCFDE
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 PLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 EIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIALSLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 IKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKIISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGG
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 ELFDKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKIT
::::::::::::::::::::::::::::: ::
XP_011 ELFDKVVGNKRLKEATCKLYFYQMLLAVQ-----------------------------IT
370 380 390
420 430 440 450 460 470
pF1KB8 DFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFGHSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPF
400 410 420 430 440 450
480 490 500 510 520 530
pF1KB8 SEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEHRTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQ
460 470 480 490 500 510
540 550 560 570 580
pF1KB8 DEDMKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEDMKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
520 530 540 550 560
>>NP_001244316 (OMIM: 114480,176807,259500,604373,609265 (322 aa)
initn: 2107 init1: 2107 opt: 2107 Z-score: 932.3 bits: 181.6 E(85289): 3.5e-45
Smith-Waterman score: 2107; 100.0% identity (100.0% similar) in 322 aa overlap (265-586:1-322)
240 250 260 270 280 290
pF1KB8 SLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKII
::::::::::::::::::::::::::::::
NP_001 MSKTLGSGACGEVKLAFERKTCKKVAIKII
10 20 30
300 310 320 330 340 350
pF1KB8 SKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFD
40 50 60 70 80 90
360 370 380 390 400 410
pF1KB8 KVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGH
100 110 120 130 140 150
420 430 440 450 460 470
pF1KB8 SKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHR
160 170 180 190 200 210
480 490 500 510 520 530
pF1KB8 TQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDM
220 230 240 250 260 270
540 550 560 570 580
pF1KB8 KRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
280 290 300 310 320
>>XP_011528147 (OMIM: 114480,176807,259500,604373,609265 (322 aa)
initn: 2107 init1: 2107 opt: 2107 Z-score: 932.3 bits: 181.6 E(85289): 3.5e-45
Smith-Waterman score: 2107; 100.0% identity (100.0% similar) in 322 aa overlap (265-586:1-322)
240 250 260 270 280 290
pF1KB8 SLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKII
::::::::::::::::::::::::::::::
XP_011 MSKTLGSGACGEVKLAFERKTCKKVAIKII
10 20 30
300 310 320 330 340 350
pF1KB8 SKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFD
40 50 60 70 80 90
360 370 380 390 400 410
pF1KB8 KVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGH
100 110 120 130 140 150
420 430 440 450 460 470
pF1KB8 SKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHR
160 170 180 190 200 210
480 490 500 510 520 530
pF1KB8 TQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDM
220 230 240 250 260 270
540 550 560 570 580
pF1KB8 KRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
280 290 300 310 320
>>XP_016884050 (OMIM: 114480,176807,259500,604373,609265 (322 aa)
initn: 2107 init1: 2107 opt: 2107 Z-score: 932.3 bits: 181.6 E(85289): 3.5e-45
Smith-Waterman score: 2107; 100.0% identity (100.0% similar) in 322 aa overlap (265-586:1-322)
240 250 260 270 280 290
pF1KB8 SLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTLGSGACGEVKLAFERKTCKKVAIKII
::::::::::::::::::::::::::::::
XP_016 MSKTLGSGACGEVKLAFERKTCKKVAIKII
10 20 30
300 310 320 330 340 350
pF1KB8 SKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELFD
40 50 60 70 80 90
360 370 380 390 400 410
pF1KB8 KVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFGH
100 110 120 130 140 150
420 430 440 450 460 470
pF1KB8 SKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEHR
160 170 180 190 200 210
480 490 500 510 520 530
pF1KB8 TQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDEDM
220 230 240 250 260 270
540 550 560 570 580
pF1KB8 KRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
280 290 300 310 320
>>XP_006724179 (OMIM: 114480,176807,259500,604373,609265 (362 aa)
initn: 2071 init1: 2071 opt: 2072 Z-score: 916.8 bits: 178.9 E(85289): 2.5e-44
Smith-Waterman score: 2072; 98.5% identity (98.8% similar) in 323 aa overlap (265-586:40-362)
240 250 260 270 280 290
pF1KB8 SLSRNKVFVFFDLTVDDQSVYPKALRDEYIMSKTL-GSGACGEVKLAFERKTCKKVAIKI
: . : : ::::::::::::::::::::::
XP_006 EFGADLVFLAVKPLTFYTGEVSLCPLQTGTMERLLYGIGACGEVKLAFERKTCKKVAIKI
10 20 30 40 50 60
300 310 320 330 340 350
pF1KB8 ISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ISKRKFAIGSAREADPALNVETEIEILKKLNHPCIIKIKNFFDAEDYYIVLELMEGGELF
70 80 90 100 110 120
360 370 380 390 400 410
pF1KB8 DKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DKVVGNKRLKEATCKLYFYQMLLAVQYLHENGIIHRDLKPENVLLSSQEEDCLIKITDFG
130 140 150 160 170 180
420 430 440 450 460 470
pF1KB8 HSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HSKILGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEH
190 200 210 220 230 240
480 490 500 510 520 530
pF1KB8 RTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWLQDED
250 260 270 280 290 300
540 550 560 570 580
pF1KB8 MKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKRKFQDLLSEENESTALPQVLAQPSTSRKRPREGEAEGAETTKRPAVCAAVL
310 320 330 340 350 360
586 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 21:59:36 2016 done: Sat Nov 5 21:59:38 2016
Total Scan time: 9.950 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]