FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8444, 303 aa 1>>>pF1KB8444 303 - 303 aa - 303 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6928+/-0.000956; mu= 6.0356+/- 0.057 mean_var=214.8616+/-46.230, 0's: 0 Z-trim(112.1): 89 B-trim: 4 in 1/52 Lambda= 0.087497 statistics sampled from 12843 (12932) to 12843 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.742), E-opt: 0.2 (0.397), width: 16 Scan time: 2.710 The best scores are: opt bits E(32554) CCDS13785.1 CRKL gene_id:1399|Hs108|chr22 ( 303) 2078 274.7 6.3e-74 CCDS11002.1 CRK gene_id:1398|Hs108|chr17 ( 304) 642 93.4 2.3e-19 >>CCDS13785.1 CRKL gene_id:1399|Hs108|chr22 (303 aa) initn: 2078 init1: 2078 opt: 2078 Z-score: 1440.7 bits: 274.7 E(32554): 6.3e-74 Smith-Waterman score: 2078; 100.0% identity (100.0% similar) in 303 aa overlap (1-303:1-303) 10 20 30 40 50 60 pF1KB8 MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSH 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 YIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 YIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 AEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 AEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 LVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 KAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 KAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPD 250 260 270 280 290 300 pF1KB8 ENE ::: CCDS13 ENE >>CCDS11002.1 CRK gene_id:1398|Hs108|chr17 (304 aa) initn: 1223 init1: 403 opt: 642 Z-score: 461.1 bits: 93.4 E(32554): 2.3e-19 Smith-Waterman score: 1135; 57.5% identity (73.8% similar) in 320 aa overlap (6-302:5-302) 10 20 30 40 50 60 pF1KB8 MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSH ::: .::.:: : .::::: . :::::::.:::::::: :::::::::::::::: CCDS11 MAGNFDSEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSH 10 20 30 40 50 70 80 90 100 pF1KB8 YIINSLPNR-----------------RFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAP ::::: : :..::::::: :::::::::::::::::::::. CCDS11 YIINSSGPRPPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDTTTLIEPVS 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 RYPSPPMGSVSAPNLPTAEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSA : : .. .. ... ::::.:.:: ::: ::::::::.:: : .:::::::.: CCDS11 R-------SRQGSGVILRQEEAEYVRALFDFNGNDEEDLPFKKGDILRIRDKPEEQWWNA 120 130 140 150 160 170 170 180 190 200 210 pF1KB8 RNKDGRVGMIPVPYVEKLVRSSPH------GKHGNRNSNSYGIPEPAHAYAQPQTTTPLP ....:. :::::::::: .: :.. . . . : :::. ::::... CCDS11 EDSEGKRGMIPVPYVEKYRPASASVSALIGGNQEGSHPQPLGGPEPG-PYAQPSVN---- 180 190 200 210 220 220 230 240 250 260 270 pF1KB8 AVSGSPGAAITPLPSTQNGPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEG ::::. ::::..:..:::::: ::::::::::::..::::..:..::::: CCDS11 ----------TPLPNLQNGPIYARVIQKRVPNAYDKTALALEVGELVKVTKINVSGQWEG 230 240 250 260 270 280 290 300 pF1KB8 EVNGRKGLFPFTHVKIFDPQNPDENE : ::..: ::::::...: :::::. CCDS11 ECNGKRGHFPFTHVRLLDQQNPDEDFS 280 290 300 303 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:56:09 2016 done: Fri Nov 4 12:56:09 2016 Total Scan time: 2.710 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]