FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8445, 301 aa 1>>>pF1KB8445 301 - 301 aa - 301 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3293+/-0.000704; mu= 15.9314+/- 0.043 mean_var=70.5959+/-14.084, 0's: 0 Z-trim(110.2): 13 B-trim: 0 in 0/52 Lambda= 0.152646 statistics sampled from 11413 (11420) to 11413 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.722), E-opt: 0.2 (0.351), width: 16 Scan time: 2.600 The best scores are: opt bits E(32554) CCDS33658.1 CYB5R3 gene_id:1727|Hs108|chr22 ( 301) 2075 465.6 2.1e-131 CCDS54535.1 CYB5R3 gene_id:1727|Hs108|chr22 ( 334) 2033 456.3 1.4e-128 CCDS14040.1 CYB5R3 gene_id:1727|Hs108|chr22 ( 278) 1919 431.2 4.3e-121 CCDS1431.1 CYB5R1 gene_id:51706|Hs108|chr1 ( 305) 1272 288.7 3.6e-78 CCDS7780.1 CYB5R2 gene_id:51700|Hs108|chr11 ( 276) 1174 267.1 1e-71 >>CCDS33658.1 CYB5R3 gene_id:1727|Hs108|chr22 (301 aa) initn: 2075 init1: 2075 opt: 2075 Z-score: 2472.6 bits: 465.6 E(32554): 2.1e-131 Smith-Waterman score: 2075; 100.0% identity (100.0% similar) in 301 aa overlap (1-301:1-301) 10 20 30 40 50 60 pF1KB8 MGAQLSTLGHMVLFPVWFLYSLLMKLFQRSTPAITLESPDIKYPLRLIDREIISHDTRRF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 MGAQLSTLGHMVLFPVWFLYSLLMKLFQRSTPAITLESPDIKYPLRLIDREIISHDTRRF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 RFALPSPQHILGLPVGQHIYLSARIDGNLVVRPYTPISSDDDKGFVDLVIKVYFKDTHPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 RFALPSPQHILGLPVGQHIYLSARIDGNLVVRPYTPISSDDDKGFVDLVIKVYFKDTHPK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 FPAGGKMSQYLESMQIGDTIEFRGPSGLLVYQGKGKFAIRPDKKSNPIIRTVKSVGMIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 FPAGGKMSQYLESMQIGDTIEFRGPSGLLVYQGKGKFAIRPDKKSNPIIRTVKSVGMIAG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 GTGITPMLQVIRAIMKDPDDHTVCHLLFANQTEKDILLRPELEELRNKHSARFKLWYTLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 GTGITPMLQVIRAIMKDPDDHTVCHLLFANQTEKDILLRPELEELRNKHSARFKLWYTLD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 RAPEAWDYGQGFVNEEMIRDHLPPPEEEPLVLMCGPPPMIQYACLPNLDHVGHPTERCFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 RAPEAWDYGQGFVNEEMIRDHLPPPEEEPLVLMCGPPPMIQYACLPNLDHVGHPTERCFV 250 260 270 280 290 300 pF1KB8 F : CCDS33 F >>CCDS54535.1 CYB5R3 gene_id:1727|Hs108|chr22 (334 aa) initn: 2033 init1: 2033 opt: 2033 Z-score: 2422.0 bits: 456.3 E(32554): 1.4e-128 Smith-Waterman score: 2033; 100.0% identity (100.0% similar) in 294 aa overlap (8-301:41-334) 10 20 30 pF1KB8 MGAQLSTLGHMVLFPVWFLYSLLMKLFQRSTPAITLE :::::::::::::::::::::::::::::: CCDS54 QSKDIWGREESICERLKQDGLDVERAESWELGHMVLFPVWFLYSLLMKLFQRSTPAITLE 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB8 SPDIKYPLRLIDREIISHDTRRFRFALPSPQHILGLPVGQHIYLSARIDGNLVVRPYTPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 SPDIKYPLRLIDREIISHDTRRFRFALPSPQHILGLPVGQHIYLSARIDGNLVVRPYTPI 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB8 SSDDDKGFVDLVIKVYFKDTHPKFPAGGKMSQYLESMQIGDTIEFRGPSGLLVYQGKGKF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 SSDDDKGFVDLVIKVYFKDTHPKFPAGGKMSQYLESMQIGDTIEFRGPSGLLVYQGKGKF 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB8 AIRPDKKSNPIIRTVKSVGMIAGGTGITPMLQVIRAIMKDPDDHTVCHLLFANQTEKDIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 AIRPDKKSNPIIRTVKSVGMIAGGTGITPMLQVIRAIMKDPDDHTVCHLLFANQTEKDIL 200 210 220 230 240 250 220 230 240 250 260 270 pF1KB8 LRPELEELRNKHSARFKLWYTLDRAPEAWDYGQGFVNEEMIRDHLPPPEEEPLVLMCGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 LRPELEELRNKHSARFKLWYTLDRAPEAWDYGQGFVNEEMIRDHLPPPEEEPLVLMCGPP 260 270 280 290 300 310 280 290 300 pF1KB8 PMIQYACLPNLDHVGHPTERCFVF :::::::::::::::::::::::: CCDS54 PMIQYACLPNLDHVGHPTERCFVF 320 330 >>CCDS14040.1 CYB5R3 gene_id:1727|Hs108|chr22 (278 aa) initn: 1919 init1: 1919 opt: 1919 Z-score: 2287.5 bits: 431.2 E(32554): 4.3e-121 Smith-Waterman score: 1919; 100.0% identity (100.0% similar) in 278 aa overlap (24-301:1-278) 10 20 30 40 50 60 pF1KB8 MGAQLSTLGHMVLFPVWFLYSLLMKLFQRSTPAITLESPDIKYPLRLIDREIISHDTRRF ::::::::::::::::::::::::::::::::::::: CCDS14 MKLFQRSTPAITLESPDIKYPLRLIDREIISHDTRRF 10 20 30 70 80 90 100 110 120 pF1KB8 RFALPSPQHILGLPVGQHIYLSARIDGNLVVRPYTPISSDDDKGFVDLVIKVYFKDTHPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 RFALPSPQHILGLPVGQHIYLSARIDGNLVVRPYTPISSDDDKGFVDLVIKVYFKDTHPK 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB8 FPAGGKMSQYLESMQIGDTIEFRGPSGLLVYQGKGKFAIRPDKKSNPIIRTVKSVGMIAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 FPAGGKMSQYLESMQIGDTIEFRGPSGLLVYQGKGKFAIRPDKKSNPIIRTVKSVGMIAG 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB8 GTGITPMLQVIRAIMKDPDDHTVCHLLFANQTEKDILLRPELEELRNKHSARFKLWYTLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GTGITPMLQVIRAIMKDPDDHTVCHLLFANQTEKDILLRPELEELRNKHSARFKLWYTLD 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB8 RAPEAWDYGQGFVNEEMIRDHLPPPEEEPLVLMCGPPPMIQYACLPNLDHVGHPTERCFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 RAPEAWDYGQGFVNEEMIRDHLPPPEEEPLVLMCGPPPMIQYACLPNLDHVGHPTERCFV 220 230 240 250 260 270 pF1KB8 F : CCDS14 F >>CCDS1431.1 CYB5R1 gene_id:51706|Hs108|chr1 (305 aa) initn: 1296 init1: 1250 opt: 1272 Z-score: 1516.8 bits: 288.7 E(32554): 3.6e-78 Smith-Waterman score: 1272; 63.5% identity (85.9% similar) in 277 aa overlap (26-301:29-305) 10 20 30 40 50 pF1KB8 MGAQLSTLGHMVLFPVWFLYSLLMKLFQRST-PAITLESPDIKYPLRLIDREIISHD : .:: : .:: .:. :: :::.:. .::. CCDS14 MGIQTSPVLLASLGVGLVTLLGLAVGSYLVRRSRRPQVTLLDPNEKYLLRLLDKTTVSHN 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 TRRFRFALPSPQHILGLPVGQHIYLSARIDGNLVVRPYTPISSDDDKGFVDLVIKVYFKD :.:::::::. .: ::::::.:::::.::::.::.:::::..::.:.:.::::::::.: CCDS14 TKRFRFALPTAHHTLGLPVGKHIYLSTRIDGSLVIRPYTPVTSDEDQGYVDLVIKVYLKG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 THPKFPAGGKMSQYLESMQIGDTIEFRGPSGLLVYQGKGKFAIRPDKKSNPIIRTVKSVG .::::: ::::::::.:...::..:::::::::.: :::.: :.:.::: : :..:..: CCDS14 VHPKFPEGGKMSQYLDSLKVGDVVEFRGPSGLLTYTGKGHFNIQPNKKSPPEPRVAKKLG 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 MIAGGTGITPMLQVIRAIMKDPDDHTVCHLLFANQTEKDILLRPELEELRNKHSARFKLW :::::::::::::.::::.: :.: : : :::::::::::.:: .::::. .. ::::: CCDS14 MIAGGTGITPMLQLIRAILKVPEDPTQCFLLFANQTEKDIILREDLEELQARYPNRFKLW 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB8 YTLDRAPEAWDYGQGFVNEEMIRDHLPPPEEEPLVLMCGPPPMIQYACLPNLDHVGHPTE .:::. :. : :..:::. .:::.::: : .. :::.::::::.: :: ::::..:. . CCDS14 FTLDHPPKDWAYSKGFVTADMIREHLPAPGDDVLVLLCGPPPMVQLACHPNLDKLGYSQK 250 260 270 280 290 300 300 pF1KB8 RCFVF :.. CCDS14 MRFTY >>CCDS7780.1 CYB5R2 gene_id:51700|Hs108|chr11 (276 aa) initn: 1216 init1: 1170 opt: 1174 Z-score: 1400.8 bits: 267.1 E(32554): 1e-71 Smith-Waterman score: 1174; 59.9% identity (82.8% similar) in 274 aa overlap (28-301:4-276) 10 20 30 40 50 60 pF1KB8 MGAQLSTLGHMVLFPVWFLYSLLMKLFQRSTPAITLESPDIKYPLRLIDREIISHDTRRF .: : :::..:. :::: ::..: :::.:::: CCDS77 MNSRRREP-ITLQDPEAKYPLPLIEKEKISHNTRRF 10 20 30 70 80 90 100 110 120 pF1KB8 RFALPSPQHILGLPVGQHIYLSARIDGNLVVRPYTPISSDDDKGFVDLVIKVYFKDTHPK ::.::::.:.::::::... : :.::..:::: :::.:::::.:::::.::.:::..::. CCDS77 RFGLPSPDHVLGLPVGNYVQLLAKIDNELVVRAYTPVSSDDDRGFVDLIIKIYFKNVHPQ 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB8 FPAGGKMSQYLESMQIGDTIEFRGPSGLLVYQGKGKFAIRPDKKSNPIIRTVKSVGMIAG .: ::::.::::.:.::.:: :::: : : :.: :...::::. :.: . .::::: CCDS77 YPEGGKMTQYLENMKIGETIFFRGPRGRLFYHGPGNLGIRPDQTSEPKKTLADHLGMIAG 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB8 GTGITPMLQVIRAIMKDPDDHTVCHLLFANQTEKDILLRPELEELRNKHSARFKLWYTLD :::::::::.:: : :::.:.: :.::::::.:::.: ::::. : .:.:::::: CCDS77 GTGITPMLQLIRHITKDPSDRTRMSLIFANQTEEDILVRKELEEIARTHPDQFNLWYTLD 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB8 RAPEAWDYGQGFVNEEMIRDHLPPPEEEPLVLMCGPPPMIQYACLPNLDHVGHPTERCFV : : .: :..:::. .::..::::: . :.:.:::::.:: : :::...:. . :. CCDS77 RPPIGWKYSSGFVTADMIKEHLPPPAKSTLILVCGPPPLIQTAAHPNLEKLGYTQDMIFT 220 230 240 250 260 270 pF1KB8 F . CCDS77 Y 301 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:56:45 2016 done: Fri Nov 4 12:56:46 2016 Total Scan time: 2.600 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]