FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8454, 533 aa 1>>>pF1KB8454 533 - 533 aa - 533 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.8708+/-0.000307; mu= 12.0331+/- 0.019 mean_var=115.1851+/-22.939, 0's: 0 Z-trim(120.6): 17 B-trim: 675 in 2/54 Lambda= 0.119502 statistics sampled from 35966 (35984) to 35966 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.756), E-opt: 0.2 (0.422), width: 16 Scan time: 11.390 The best scores are: opt bits E(85289) XP_011528488 (OMIM: 604621) PREDICTED: beta-1,4-ma ( 533) 3801 666.0 7.9e-191 NP_002400 (OMIM: 604621) beta-1,4-mannosyl-glycopr ( 533) 3801 666.0 7.9e-191 XP_005261666 (OMIM: 604621) PREDICTED: beta-1,4-ma ( 533) 3801 666.0 7.9e-191 XP_011528491 (OMIM: 604621) PREDICTED: beta-1,4-ma ( 533) 3801 666.0 7.9e-191 XP_011528486 (OMIM: 604621) PREDICTED: beta-1,4-ma ( 533) 3801 666.0 7.9e-191 XP_011528487 (OMIM: 604621) PREDICTED: beta-1,4-ma ( 533) 3801 666.0 7.9e-191 XP_011528489 (OMIM: 604621) PREDICTED: beta-1,4-ma ( 533) 3801 666.0 7.9e-191 XP_011528494 (OMIM: 604621) PREDICTED: beta-1,4-ma ( 533) 3801 666.0 7.9e-191 XP_011528490 (OMIM: 604621) PREDICTED: beta-1,4-ma ( 533) 3801 666.0 7.9e-191 NP_001091740 (OMIM: 604621) beta-1,4-mannosyl-glyc ( 533) 3801 666.0 7.9e-191 XP_016884291 (OMIM: 604621) PREDICTED: beta-1,4-ma ( 533) 3801 666.0 7.9e-191 XP_011528492 (OMIM: 604621) PREDICTED: beta-1,4-ma ( 533) 3801 666.0 7.9e-191 XP_011528493 (OMIM: 604621) PREDICTED: beta-1,4-ma ( 533) 3801 666.0 7.9e-191 XP_011528496 (OMIM: 604621) PREDICTED: beta-1,4-ma ( 533) 3801 666.0 7.9e-191 XP_006724315 (OMIM: 604621) PREDICTED: beta-1,4-ma ( 561) 3801 666.0 8.3e-191 XP_005261665 (OMIM: 604621) PREDICTED: beta-1,4-ma ( 575) 3801 666.0 8.5e-191 >>XP_011528488 (OMIM: 604621) PREDICTED: beta-1,4-mannos (533 aa) initn: 3801 init1: 3801 opt: 3801 Z-score: 3546.9 bits: 666.0 E(85289): 7.9e-191 Smith-Waterman score: 3801; 100.0% identity (100.0% similar) in 533 aa overlap (1-533:1-533) 10 20 30 40 50 60 pF1KB8 MKMRRYKLFLMFCMAGLCLISFLHFFKTLSYVTFPRELASLSPNLVSSFFWNNAPVTPQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKMRRYKLFLMFCMAGLCLISFLHFFKTLSYVTFPRELASLSPNLVSSFFWNNAPVTPQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SPEPGGPDLLRTPLYSHSPLLQPLPPSKAAEELHRVDLVLPEDTTEYFVRTKAGGVCFKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPEPGGPDLLRTPLYSHSPLLQPLPPSKAAEELHRVDLVLPEDTTEYFVRTKAGGVCFKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 GTKMLERPPPGRPEEKPEGANGSSARRPPRYLLSARERTGGRGARRKWVECVCLPGWHGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTKMLERPPPGRPEEKPEGANGSSARRPPRYLLSARERTGGRGARRKWVECVCLPGWHGP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SCGVPTVVQYSNLPTKERLVPREVPRRVINAINVNHEFDLLDVRFHELGDVVDAFVVCES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCGVPTVVQYSNLPTKERLVPREVPRRVINAINVNHEFDLLDVRFHELGDVVDAFVVCES 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NFTAYGEPRPLKFREMLTNGTFEYIRHKVLYVFLDHFPPGGRQDGWIADDYLRTFLTQDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NFTAYGEPRPLKFREMLTNGTFEYIRHKVLYVFLDHFPPGGRQDGWIADDYLRTFLTQDG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 VSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 VVSGCTVDMLQAVYGLDGIRLRRRQYYTMPNFRQYENRTGHILVQWSLGSPLHFAGWHCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVSGCTVDMLQAVYGLDGIRLRRRQYYTMPNFRQYENRTGHILVQWSLGSPLHFAGWHCS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 WCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRGLIRTGGWFDGTQQEYPPADPSEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRGLIRTGGWFDGTQQEYPPADPSEH 430 440 450 460 470 480 490 500 510 520 530 pF1KB8 MYAPKYLLKNYDRFHYLLDNPYQEPRSTAAGGWRHRGPEGRPPARGKLDEAEV ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYAPKYLLKNYDRFHYLLDNPYQEPRSTAAGGWRHRGPEGRPPARGKLDEAEV 490 500 510 520 530 >>NP_002400 (OMIM: 604621) beta-1,4-mannosyl-glycoprotei (533 aa) initn: 3801 init1: 3801 opt: 3801 Z-score: 3546.9 bits: 666.0 E(85289): 7.9e-191 Smith-Waterman score: 3801; 100.0% identity (100.0% similar) in 533 aa overlap (1-533:1-533) 10 20 30 40 50 60 pF1KB8 MKMRRYKLFLMFCMAGLCLISFLHFFKTLSYVTFPRELASLSPNLVSSFFWNNAPVTPQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MKMRRYKLFLMFCMAGLCLISFLHFFKTLSYVTFPRELASLSPNLVSSFFWNNAPVTPQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SPEPGGPDLLRTPLYSHSPLLQPLPPSKAAEELHRVDLVLPEDTTEYFVRTKAGGVCFKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SPEPGGPDLLRTPLYSHSPLLQPLPPSKAAEELHRVDLVLPEDTTEYFVRTKAGGVCFKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 GTKMLERPPPGRPEEKPEGANGSSARRPPRYLLSARERTGGRGARRKWVECVCLPGWHGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GTKMLERPPPGRPEEKPEGANGSSARRPPRYLLSARERTGGRGARRKWVECVCLPGWHGP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SCGVPTVVQYSNLPTKERLVPREVPRRVINAINVNHEFDLLDVRFHELGDVVDAFVVCES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 SCGVPTVVQYSNLPTKERLVPREVPRRVINAINVNHEFDLLDVRFHELGDVVDAFVVCES 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NFTAYGEPRPLKFREMLTNGTFEYIRHKVLYVFLDHFPPGGRQDGWIADDYLRTFLTQDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NFTAYGEPRPLKFREMLTNGTFEYIRHKVLYVFLDHFPPGGRQDGWIADDYLRTFLTQDG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 VSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 VVSGCTVDMLQAVYGLDGIRLRRRQYYTMPNFRQYENRTGHILVQWSLGSPLHFAGWHCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VVSGCTVDMLQAVYGLDGIRLRRRQYYTMPNFRQYENRTGHILVQWSLGSPLHFAGWHCS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 WCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRGLIRTGGWFDGTQQEYPPADPSEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 WCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRGLIRTGGWFDGTQQEYPPADPSEH 430 440 450 460 470 480 490 500 510 520 530 pF1KB8 MYAPKYLLKNYDRFHYLLDNPYQEPRSTAAGGWRHRGPEGRPPARGKLDEAEV ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MYAPKYLLKNYDRFHYLLDNPYQEPRSTAAGGWRHRGPEGRPPARGKLDEAEV 490 500 510 520 530 >>XP_005261666 (OMIM: 604621) PREDICTED: beta-1,4-mannos (533 aa) initn: 3801 init1: 3801 opt: 3801 Z-score: 3546.9 bits: 666.0 E(85289): 7.9e-191 Smith-Waterman score: 3801; 100.0% identity (100.0% similar) in 533 aa overlap (1-533:1-533) 10 20 30 40 50 60 pF1KB8 MKMRRYKLFLMFCMAGLCLISFLHFFKTLSYVTFPRELASLSPNLVSSFFWNNAPVTPQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MKMRRYKLFLMFCMAGLCLISFLHFFKTLSYVTFPRELASLSPNLVSSFFWNNAPVTPQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SPEPGGPDLLRTPLYSHSPLLQPLPPSKAAEELHRVDLVLPEDTTEYFVRTKAGGVCFKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPEPGGPDLLRTPLYSHSPLLQPLPPSKAAEELHRVDLVLPEDTTEYFVRTKAGGVCFKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 GTKMLERPPPGRPEEKPEGANGSSARRPPRYLLSARERTGGRGARRKWVECVCLPGWHGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GTKMLERPPPGRPEEKPEGANGSSARRPPRYLLSARERTGGRGARRKWVECVCLPGWHGP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SCGVPTVVQYSNLPTKERLVPREVPRRVINAINVNHEFDLLDVRFHELGDVVDAFVVCES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SCGVPTVVQYSNLPTKERLVPREVPRRVINAINVNHEFDLLDVRFHELGDVVDAFVVCES 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NFTAYGEPRPLKFREMLTNGTFEYIRHKVLYVFLDHFPPGGRQDGWIADDYLRTFLTQDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NFTAYGEPRPLKFREMLTNGTFEYIRHKVLYVFLDHFPPGGRQDGWIADDYLRTFLTQDG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 VSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 VVSGCTVDMLQAVYGLDGIRLRRRQYYTMPNFRQYENRTGHILVQWSLGSPLHFAGWHCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VVSGCTVDMLQAVYGLDGIRLRRRQYYTMPNFRQYENRTGHILVQWSLGSPLHFAGWHCS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 WCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRGLIRTGGWFDGTQQEYPPADPSEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRGLIRTGGWFDGTQQEYPPADPSEH 430 440 450 460 470 480 490 500 510 520 530 pF1KB8 MYAPKYLLKNYDRFHYLLDNPYQEPRSTAAGGWRHRGPEGRPPARGKLDEAEV ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MYAPKYLLKNYDRFHYLLDNPYQEPRSTAAGGWRHRGPEGRPPARGKLDEAEV 490 500 510 520 530 >>XP_011528491 (OMIM: 604621) PREDICTED: beta-1,4-mannos (533 aa) initn: 3801 init1: 3801 opt: 3801 Z-score: 3546.9 bits: 666.0 E(85289): 7.9e-191 Smith-Waterman score: 3801; 100.0% identity (100.0% similar) in 533 aa overlap (1-533:1-533) 10 20 30 40 50 60 pF1KB8 MKMRRYKLFLMFCMAGLCLISFLHFFKTLSYVTFPRELASLSPNLVSSFFWNNAPVTPQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKMRRYKLFLMFCMAGLCLISFLHFFKTLSYVTFPRELASLSPNLVSSFFWNNAPVTPQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SPEPGGPDLLRTPLYSHSPLLQPLPPSKAAEELHRVDLVLPEDTTEYFVRTKAGGVCFKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPEPGGPDLLRTPLYSHSPLLQPLPPSKAAEELHRVDLVLPEDTTEYFVRTKAGGVCFKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 GTKMLERPPPGRPEEKPEGANGSSARRPPRYLLSARERTGGRGARRKWVECVCLPGWHGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTKMLERPPPGRPEEKPEGANGSSARRPPRYLLSARERTGGRGARRKWVECVCLPGWHGP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SCGVPTVVQYSNLPTKERLVPREVPRRVINAINVNHEFDLLDVRFHELGDVVDAFVVCES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCGVPTVVQYSNLPTKERLVPREVPRRVINAINVNHEFDLLDVRFHELGDVVDAFVVCES 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NFTAYGEPRPLKFREMLTNGTFEYIRHKVLYVFLDHFPPGGRQDGWIADDYLRTFLTQDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NFTAYGEPRPLKFREMLTNGTFEYIRHKVLYVFLDHFPPGGRQDGWIADDYLRTFLTQDG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 VSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 VVSGCTVDMLQAVYGLDGIRLRRRQYYTMPNFRQYENRTGHILVQWSLGSPLHFAGWHCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVSGCTVDMLQAVYGLDGIRLRRRQYYTMPNFRQYENRTGHILVQWSLGSPLHFAGWHCS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 WCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRGLIRTGGWFDGTQQEYPPADPSEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRGLIRTGGWFDGTQQEYPPADPSEH 430 440 450 460 470 480 490 500 510 520 530 pF1KB8 MYAPKYLLKNYDRFHYLLDNPYQEPRSTAAGGWRHRGPEGRPPARGKLDEAEV ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYAPKYLLKNYDRFHYLLDNPYQEPRSTAAGGWRHRGPEGRPPARGKLDEAEV 490 500 510 520 530 >>XP_011528486 (OMIM: 604621) PREDICTED: beta-1,4-mannos (533 aa) initn: 3801 init1: 3801 opt: 3801 Z-score: 3546.9 bits: 666.0 E(85289): 7.9e-191 Smith-Waterman score: 3801; 100.0% identity (100.0% similar) in 533 aa overlap (1-533:1-533) 10 20 30 40 50 60 pF1KB8 MKMRRYKLFLMFCMAGLCLISFLHFFKTLSYVTFPRELASLSPNLVSSFFWNNAPVTPQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKMRRYKLFLMFCMAGLCLISFLHFFKTLSYVTFPRELASLSPNLVSSFFWNNAPVTPQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SPEPGGPDLLRTPLYSHSPLLQPLPPSKAAEELHRVDLVLPEDTTEYFVRTKAGGVCFKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPEPGGPDLLRTPLYSHSPLLQPLPPSKAAEELHRVDLVLPEDTTEYFVRTKAGGVCFKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 GTKMLERPPPGRPEEKPEGANGSSARRPPRYLLSARERTGGRGARRKWVECVCLPGWHGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTKMLERPPPGRPEEKPEGANGSSARRPPRYLLSARERTGGRGARRKWVECVCLPGWHGP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SCGVPTVVQYSNLPTKERLVPREVPRRVINAINVNHEFDLLDVRFHELGDVVDAFVVCES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCGVPTVVQYSNLPTKERLVPREVPRRVINAINVNHEFDLLDVRFHELGDVVDAFVVCES 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NFTAYGEPRPLKFREMLTNGTFEYIRHKVLYVFLDHFPPGGRQDGWIADDYLRTFLTQDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NFTAYGEPRPLKFREMLTNGTFEYIRHKVLYVFLDHFPPGGRQDGWIADDYLRTFLTQDG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 VSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 VVSGCTVDMLQAVYGLDGIRLRRRQYYTMPNFRQYENRTGHILVQWSLGSPLHFAGWHCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVSGCTVDMLQAVYGLDGIRLRRRQYYTMPNFRQYENRTGHILVQWSLGSPLHFAGWHCS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 WCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRGLIRTGGWFDGTQQEYPPADPSEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRGLIRTGGWFDGTQQEYPPADPSEH 430 440 450 460 470 480 490 500 510 520 530 pF1KB8 MYAPKYLLKNYDRFHYLLDNPYQEPRSTAAGGWRHRGPEGRPPARGKLDEAEV ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYAPKYLLKNYDRFHYLLDNPYQEPRSTAAGGWRHRGPEGRPPARGKLDEAEV 490 500 510 520 530 >>XP_011528487 (OMIM: 604621) PREDICTED: beta-1,4-mannos (533 aa) initn: 3801 init1: 3801 opt: 3801 Z-score: 3546.9 bits: 666.0 E(85289): 7.9e-191 Smith-Waterman score: 3801; 100.0% identity (100.0% similar) in 533 aa overlap (1-533:1-533) 10 20 30 40 50 60 pF1KB8 MKMRRYKLFLMFCMAGLCLISFLHFFKTLSYVTFPRELASLSPNLVSSFFWNNAPVTPQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKMRRYKLFLMFCMAGLCLISFLHFFKTLSYVTFPRELASLSPNLVSSFFWNNAPVTPQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SPEPGGPDLLRTPLYSHSPLLQPLPPSKAAEELHRVDLVLPEDTTEYFVRTKAGGVCFKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPEPGGPDLLRTPLYSHSPLLQPLPPSKAAEELHRVDLVLPEDTTEYFVRTKAGGVCFKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 GTKMLERPPPGRPEEKPEGANGSSARRPPRYLLSARERTGGRGARRKWVECVCLPGWHGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTKMLERPPPGRPEEKPEGANGSSARRPPRYLLSARERTGGRGARRKWVECVCLPGWHGP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SCGVPTVVQYSNLPTKERLVPREVPRRVINAINVNHEFDLLDVRFHELGDVVDAFVVCES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCGVPTVVQYSNLPTKERLVPREVPRRVINAINVNHEFDLLDVRFHELGDVVDAFVVCES 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NFTAYGEPRPLKFREMLTNGTFEYIRHKVLYVFLDHFPPGGRQDGWIADDYLRTFLTQDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NFTAYGEPRPLKFREMLTNGTFEYIRHKVLYVFLDHFPPGGRQDGWIADDYLRTFLTQDG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 VSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 VVSGCTVDMLQAVYGLDGIRLRRRQYYTMPNFRQYENRTGHILVQWSLGSPLHFAGWHCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVSGCTVDMLQAVYGLDGIRLRRRQYYTMPNFRQYENRTGHILVQWSLGSPLHFAGWHCS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 WCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRGLIRTGGWFDGTQQEYPPADPSEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRGLIRTGGWFDGTQQEYPPADPSEH 430 440 450 460 470 480 490 500 510 520 530 pF1KB8 MYAPKYLLKNYDRFHYLLDNPYQEPRSTAAGGWRHRGPEGRPPARGKLDEAEV ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYAPKYLLKNYDRFHYLLDNPYQEPRSTAAGGWRHRGPEGRPPARGKLDEAEV 490 500 510 520 530 >>XP_011528489 (OMIM: 604621) PREDICTED: beta-1,4-mannos (533 aa) initn: 3801 init1: 3801 opt: 3801 Z-score: 3546.9 bits: 666.0 E(85289): 7.9e-191 Smith-Waterman score: 3801; 100.0% identity (100.0% similar) in 533 aa overlap (1-533:1-533) 10 20 30 40 50 60 pF1KB8 MKMRRYKLFLMFCMAGLCLISFLHFFKTLSYVTFPRELASLSPNLVSSFFWNNAPVTPQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKMRRYKLFLMFCMAGLCLISFLHFFKTLSYVTFPRELASLSPNLVSSFFWNNAPVTPQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SPEPGGPDLLRTPLYSHSPLLQPLPPSKAAEELHRVDLVLPEDTTEYFVRTKAGGVCFKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPEPGGPDLLRTPLYSHSPLLQPLPPSKAAEELHRVDLVLPEDTTEYFVRTKAGGVCFKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 GTKMLERPPPGRPEEKPEGANGSSARRPPRYLLSARERTGGRGARRKWVECVCLPGWHGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTKMLERPPPGRPEEKPEGANGSSARRPPRYLLSARERTGGRGARRKWVECVCLPGWHGP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SCGVPTVVQYSNLPTKERLVPREVPRRVINAINVNHEFDLLDVRFHELGDVVDAFVVCES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCGVPTVVQYSNLPTKERLVPREVPRRVINAINVNHEFDLLDVRFHELGDVVDAFVVCES 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NFTAYGEPRPLKFREMLTNGTFEYIRHKVLYVFLDHFPPGGRQDGWIADDYLRTFLTQDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NFTAYGEPRPLKFREMLTNGTFEYIRHKVLYVFLDHFPPGGRQDGWIADDYLRTFLTQDG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 VSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 VVSGCTVDMLQAVYGLDGIRLRRRQYYTMPNFRQYENRTGHILVQWSLGSPLHFAGWHCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVSGCTVDMLQAVYGLDGIRLRRRQYYTMPNFRQYENRTGHILVQWSLGSPLHFAGWHCS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 WCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRGLIRTGGWFDGTQQEYPPADPSEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRGLIRTGGWFDGTQQEYPPADPSEH 430 440 450 460 470 480 490 500 510 520 530 pF1KB8 MYAPKYLLKNYDRFHYLLDNPYQEPRSTAAGGWRHRGPEGRPPARGKLDEAEV ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYAPKYLLKNYDRFHYLLDNPYQEPRSTAAGGWRHRGPEGRPPARGKLDEAEV 490 500 510 520 530 >>XP_011528494 (OMIM: 604621) PREDICTED: beta-1,4-mannos (533 aa) initn: 3801 init1: 3801 opt: 3801 Z-score: 3546.9 bits: 666.0 E(85289): 7.9e-191 Smith-Waterman score: 3801; 100.0% identity (100.0% similar) in 533 aa overlap (1-533:1-533) 10 20 30 40 50 60 pF1KB8 MKMRRYKLFLMFCMAGLCLISFLHFFKTLSYVTFPRELASLSPNLVSSFFWNNAPVTPQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKMRRYKLFLMFCMAGLCLISFLHFFKTLSYVTFPRELASLSPNLVSSFFWNNAPVTPQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SPEPGGPDLLRTPLYSHSPLLQPLPPSKAAEELHRVDLVLPEDTTEYFVRTKAGGVCFKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPEPGGPDLLRTPLYSHSPLLQPLPPSKAAEELHRVDLVLPEDTTEYFVRTKAGGVCFKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 GTKMLERPPPGRPEEKPEGANGSSARRPPRYLLSARERTGGRGARRKWVECVCLPGWHGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTKMLERPPPGRPEEKPEGANGSSARRPPRYLLSARERTGGRGARRKWVECVCLPGWHGP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SCGVPTVVQYSNLPTKERLVPREVPRRVINAINVNHEFDLLDVRFHELGDVVDAFVVCES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCGVPTVVQYSNLPTKERLVPREVPRRVINAINVNHEFDLLDVRFHELGDVVDAFVVCES 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NFTAYGEPRPLKFREMLTNGTFEYIRHKVLYVFLDHFPPGGRQDGWIADDYLRTFLTQDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NFTAYGEPRPLKFREMLTNGTFEYIRHKVLYVFLDHFPPGGRQDGWIADDYLRTFLTQDG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 VSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 VVSGCTVDMLQAVYGLDGIRLRRRQYYTMPNFRQYENRTGHILVQWSLGSPLHFAGWHCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVSGCTVDMLQAVYGLDGIRLRRRQYYTMPNFRQYENRTGHILVQWSLGSPLHFAGWHCS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 WCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRGLIRTGGWFDGTQQEYPPADPSEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRGLIRTGGWFDGTQQEYPPADPSEH 430 440 450 460 470 480 490 500 510 520 530 pF1KB8 MYAPKYLLKNYDRFHYLLDNPYQEPRSTAAGGWRHRGPEGRPPARGKLDEAEV ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYAPKYLLKNYDRFHYLLDNPYQEPRSTAAGGWRHRGPEGRPPARGKLDEAEV 490 500 510 520 530 >>XP_011528490 (OMIM: 604621) PREDICTED: beta-1,4-mannos (533 aa) initn: 3801 init1: 3801 opt: 3801 Z-score: 3546.9 bits: 666.0 E(85289): 7.9e-191 Smith-Waterman score: 3801; 100.0% identity (100.0% similar) in 533 aa overlap (1-533:1-533) 10 20 30 40 50 60 pF1KB8 MKMRRYKLFLMFCMAGLCLISFLHFFKTLSYVTFPRELASLSPNLVSSFFWNNAPVTPQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKMRRYKLFLMFCMAGLCLISFLHFFKTLSYVTFPRELASLSPNLVSSFFWNNAPVTPQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SPEPGGPDLLRTPLYSHSPLLQPLPPSKAAEELHRVDLVLPEDTTEYFVRTKAGGVCFKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPEPGGPDLLRTPLYSHSPLLQPLPPSKAAEELHRVDLVLPEDTTEYFVRTKAGGVCFKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 GTKMLERPPPGRPEEKPEGANGSSARRPPRYLLSARERTGGRGARRKWVECVCLPGWHGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTKMLERPPPGRPEEKPEGANGSSARRPPRYLLSARERTGGRGARRKWVECVCLPGWHGP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SCGVPTVVQYSNLPTKERLVPREVPRRVINAINVNHEFDLLDVRFHELGDVVDAFVVCES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SCGVPTVVQYSNLPTKERLVPREVPRRVINAINVNHEFDLLDVRFHELGDVVDAFVVCES 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NFTAYGEPRPLKFREMLTNGTFEYIRHKVLYVFLDHFPPGGRQDGWIADDYLRTFLTQDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NFTAYGEPRPLKFREMLTNGTFEYIRHKVLYVFLDHFPPGGRQDGWIADDYLRTFLTQDG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 VSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 VVSGCTVDMLQAVYGLDGIRLRRRQYYTMPNFRQYENRTGHILVQWSLGSPLHFAGWHCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVSGCTVDMLQAVYGLDGIRLRRRQYYTMPNFRQYENRTGHILVQWSLGSPLHFAGWHCS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 WCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRGLIRTGGWFDGTQQEYPPADPSEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRGLIRTGGWFDGTQQEYPPADPSEH 430 440 450 460 470 480 490 500 510 520 530 pF1KB8 MYAPKYLLKNYDRFHYLLDNPYQEPRSTAAGGWRHRGPEGRPPARGKLDEAEV ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MYAPKYLLKNYDRFHYLLDNPYQEPRSTAAGGWRHRGPEGRPPARGKLDEAEV 490 500 510 520 530 >>NP_001091740 (OMIM: 604621) beta-1,4-mannosyl-glycopro (533 aa) initn: 3801 init1: 3801 opt: 3801 Z-score: 3546.9 bits: 666.0 E(85289): 7.9e-191 Smith-Waterman score: 3801; 100.0% identity (100.0% similar) in 533 aa overlap (1-533:1-533) 10 20 30 40 50 60 pF1KB8 MKMRRYKLFLMFCMAGLCLISFLHFFKTLSYVTFPRELASLSPNLVSSFFWNNAPVTPQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKMRRYKLFLMFCMAGLCLISFLHFFKTLSYVTFPRELASLSPNLVSSFFWNNAPVTPQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 SPEPGGPDLLRTPLYSHSPLLQPLPPSKAAEELHRVDLVLPEDTTEYFVRTKAGGVCFKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPEPGGPDLLRTPLYSHSPLLQPLPPSKAAEELHRVDLVLPEDTTEYFVRTKAGGVCFKP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 GTKMLERPPPGRPEEKPEGANGSSARRPPRYLLSARERTGGRGARRKWVECVCLPGWHGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTKMLERPPPGRPEEKPEGANGSSARRPPRYLLSARERTGGRGARRKWVECVCLPGWHGP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SCGVPTVVQYSNLPTKERLVPREVPRRVINAINVNHEFDLLDVRFHELGDVVDAFVVCES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SCGVPTVVQYSNLPTKERLVPREVPRRVINAINVNHEFDLLDVRFHELGDVVDAFVVCES 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NFTAYGEPRPLKFREMLTNGTFEYIRHKVLYVFLDHFPPGGRQDGWIADDYLRTFLTQDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NFTAYGEPRPLKFREMLTNGTFEYIRHKVLYVFLDHFPPGGRQDGWIADDYLRTFLTQDG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 VSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSRLRNLRPDDVFIIDDADEIPARDGVLFLKLYDGWTEPFAFHMRKSLYGFFWKQPGTLE 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 VVSGCTVDMLQAVYGLDGIRLRRRQYYTMPNFRQYENRTGHILVQWSLGSPLHFAGWHCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVSGCTVDMLQAVYGLDGIRLRRRQYYTMPNFRQYENRTGHILVQWSLGSPLHFAGWHCS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 WCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRGLIRTGGWFDGTQQEYPPADPSEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WCFTPEGIYFKLVSAQNGDFPRWGDYEDKRDLNYIRGLIRTGGWFDGTQQEYPPADPSEH 430 440 450 460 470 480 490 500 510 520 530 pF1KB8 MYAPKYLLKNYDRFHYLLDNPYQEPRSTAAGGWRHRGPEGRPPARGKLDEAEV ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MYAPKYLLKNYDRFHYLLDNPYQEPRSTAAGGWRHRGPEGRPPARGKLDEAEV 490 500 510 520 530 533 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 13:02:49 2016 done: Fri Nov 4 13:02:51 2016 Total Scan time: 11.390 Total Display time: 0.120 Function used was FASTA [36.3.4 Apr, 2011]