FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8456, 485 aa
1>>>pF1KB8456 485 - 485 aa - 485 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.8048+/-0.000855; mu= 6.7446+/- 0.052
mean_var=124.0355+/-24.629, 0's: 0 Z-trim(110.8): 21 B-trim: 5 in 1/52
Lambda= 0.115160
statistics sampled from 11900 (11914) to 11900 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.726), E-opt: 0.2 (0.366), width: 16
Scan time: 3.830
The best scores are: opt bits E(32554)
CCDS13746.1 BCL2L13 gene_id:23786|Hs108|chr22 ( 485) 3072 521.4 8.6e-148
CCDS74810.1 BCL2L13 gene_id:23786|Hs108|chr22 ( 509) 2819 479.3 4.1e-135
CCDS59448.1 BCL2L13 gene_id:23786|Hs108|chr22 ( 323) 2039 349.7 2.8e-96
CCDS74811.1 BCL2L13 gene_id:23786|Hs108|chr22 ( 461) 1838 316.3 4.3e-86
CCDS59447.1 BCL2L13 gene_id:23786|Hs108|chr22 ( 171) 817 146.6 2e-35
CCDS74812.1 BCL2L13 gene_id:23786|Hs108|chr22 ( 128) 485 91.4 6.3e-19
CCDS74813.1 BCL2L13 gene_id:23786|Hs108|chr22 ( 80) 462 87.5 5.8e-18
>>CCDS13746.1 BCL2L13 gene_id:23786|Hs108|chr22 (485 aa)
initn: 3072 init1: 3072 opt: 3072 Z-score: 2766.8 bits: 521.4 E(32554): 8.6e-148
Smith-Waterman score: 3072; 100.0% identity (100.0% similar) in 485 aa overlap (1-485:1-485)
10 20 30 40 50 60
pF1KB8 MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 TEIEEELKSLDKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 TEIEEELKSLDKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 KALQMLLSQPVTYQAFRECTLETTVHASGWNKILVPLVLLRQMLLELTRRGQEPLSALLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 KALQMLLSQPVTYQAFRECTLETTVHASGWNKILVPLVLLRQMLLELTRRGQEPLSALLQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 FGVTYLEDYSAEYIIQQGGWGTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 FGVTYLEDYSAEYIIQQGGWGTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPES
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 PTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSEN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 NSSNSDIVHVEKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 NSSNSDIVHVEKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 DTEVITVEKSSPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 DTEVITVEKSSPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREES
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 LVEELSPASEKKPVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVAILAVAIGVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 LVEELSPASEKKPVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVAILAVAIGVAL
430 440 450 460 470 480
pF1KB8 ALRKK
:::::
CCDS13 ALRKK
>>CCDS74810.1 BCL2L13 gene_id:23786|Hs108|chr22 (509 aa)
initn: 2819 init1: 2819 opt: 2819 Z-score: 2539.3 bits: 479.3 E(32554): 4.1e-135
Smith-Waterman score: 2819; 100.0% identity (100.0% similar) in 445 aa overlap (41-485:65-509)
20 30 40 50 60 70
pF1KB8 FHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVKTEIEEELKSL
::::::::::::::::::::::::::::::
CCDS74 VGALTAAGGPCRKQLPPPPLSSLLGQGPGPGVQLDIASQSLDQEILLKVKTEIEEELKSL
40 50 60 70 80 90
80 90 100 110 120 130
pF1KB8 DKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLHKALQMLLSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 DKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLHKALQMLLSQP
100 110 120 130 140 150
140 150 160 170 180 190
pF1KB8 VTYQAFRECTLETTVHASGWNKILVPLVLLRQMLLELTRRGQEPLSALLQFGVTYLEDYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 VTYQAFRECTLETTVHASGWNKILVPLVLLRQMLLELTRRGQEPLSALLQFGVTYLEDYS
160 170 180 190 200 210
200 210 220 230 240 250
pF1KB8 AEYIIQQGGWGTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 AEYIIQQGGWGTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSE
220 230 240 250 260 270
260 270 280 290 300 310
pF1KB8 SLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSENNSSNSDIVHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 SLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSENNSSNSDIVHV
280 290 300 310 320 330
320 330 340 350 360 370
pF1KB8 EKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 EKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKS
340 350 360 370 380 390
380 390 400 410 420 430
pF1KB8 SPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 SPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASE
400 410 420 430 440 450
440 450 460 470 480
pF1KB8 KKPVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVAILAVAIGVALALRKK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 KKPVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVAILAVAIGVALALRKK
460 470 480 490 500
>>CCDS59448.1 BCL2L13 gene_id:23786|Hs108|chr22 (323 aa)
initn: 2039 init1: 2039 opt: 2039 Z-score: 1842.1 bits: 349.7 E(32554): 2.8e-96
Smith-Waterman score: 2039; 100.0% identity (100.0% similar) in 323 aa overlap (163-485:1-323)
140 150 160 170 180 190
pF1KB8 YQAFRECTLETTVHASGWNKILVPLVLLRQMLLELTRRGQEPLSALLQFGVTYLEDYSAE
::::::::::::::::::::::::::::::
CCDS59 MLLELTRRGQEPLSALLQFGVTYLEDYSAE
10 20 30
200 210 220 230 240 250
pF1KB8 YIIQQGGWGTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSESL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 YIIQQGGWGTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSESL
40 50 60 70 80 90
260 270 280 290 300 310
pF1KB8 PVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSENNSSNSDIVHVEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 PVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSENNSSNSDIVHVEK
100 110 120 130 140 150
320 330 340 350 360 370
pF1KB8 EEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 EEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSP
160 170 180 190 200 210
380 390 400 410 420 430
pF1KB8 ATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 ATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKK
220 230 240 250 260 270
440 450 460 470 480
pF1KB8 PVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVAILAVAIGVALALRKK
:::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 PVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVAILAVAIGVALALRKK
280 290 300 310 320
>>CCDS74811.1 BCL2L13 gene_id:23786|Hs108|chr22 (461 aa)
initn: 2496 init1: 1789 opt: 1838 Z-score: 1659.1 bits: 316.3 E(32554): 4.3e-86
Smith-Waterman score: 2404; 89.2% identity (89.2% similar) in 445 aa overlap (41-485:65-461)
20 30 40 50 60 70
pF1KB8 FHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVKTEIEEELKSL
::::::::::::::::::::::::::::::
CCDS74 VGALTAAGGPCRKQLPPPPLSSLLGQGPGPGVQLDIASQSLDQEILLKVKTEIEEELKSL
40 50 60 70 80 90
80 90 100 110 120 130
pF1KB8 DKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLHKALQMLLSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 DKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLHKALQMLLSQP
100 110 120 130 140 150
140 150 160 170 180 190
pF1KB8 VTYQAFRECTLETTVHASGWNKILVPLVLLRQMLLELTRRGQEPLSALLQFGVTYLEDYS
::::::::::::::::::::::
CCDS74 VTYQAFRECTLETTVHASGWNK--------------------------------------
160 170
200 210 220 230 240 250
pF1KB8 AEYIIQQGGWGTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSE
::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 ----------GTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSE
180 190 200 210 220
260 270 280 290 300 310
pF1KB8 SLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSENNSSNSDIVHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 SLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSENNSSNSDIVHV
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB8 EKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 EKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKS
290 300 310 320 330 340
380 390 400 410 420 430
pF1KB8 SPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 SPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASE
350 360 370 380 390 400
440 450 460 470 480
pF1KB8 KKPVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVAILAVAIGVALALRKK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 KKPVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVAILAVAIGVALALRKK
410 420 430 440 450 460
>>CCDS59447.1 BCL2L13 gene_id:23786|Hs108|chr22 (171 aa)
initn: 813 init1: 813 opt: 817 Z-score: 749.3 bits: 146.6 E(32554): 2e-35
Smith-Waterman score: 817; 91.7% identity (95.2% similar) in 145 aa overlap (1-143:1-145)
10 20 30 40 50 60
pF1KB8 MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 TEIEEELKSLDKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 TEIEEELKSLDKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLH
70 80 90 100 110 120
130 140 150 160 170
pF1KB8 KALQMLLSQPV--TYQAFRECTLETTVHASGWNKILVPLVLLRQMLLELTRRGQEPLSAL
::::::::: . . . :. :::.
CCDS59 KALQMLLSQALCLVLSQRRRNTLESLQKIAMTFTSCPATTLDKSVPQSLQL
130 140 150 160 170
>>CCDS74812.1 BCL2L13 gene_id:23786|Hs108|chr22 (128 aa)
initn: 485 init1: 485 opt: 485 Z-score: 453.3 bits: 91.4 E(32554): 6.3e-19
Smith-Waterman score: 485; 95.2% identity (97.6% similar) in 83 aa overlap (1-83:1-83)
10 20 30 40 50 60
pF1KB8 MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 TEIEEELKSLDKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLH
:::::::::::::::: : ..::
CCDS74 TEIEEELKSLDKEISEDFGASGFATTNAFGIDKTWSRTFERTAAVWRDIPGGLFGRVHHS
70 80 90 100 110 120
>>CCDS74813.1 BCL2L13 gene_id:23786|Hs108|chr22 (80 aa)
initn: 462 init1: 462 opt: 462 Z-score: 435.9 bits: 87.5 E(32554): 5.8e-18
Smith-Waterman score: 462; 100.0% identity (100.0% similar) in 76 aa overlap (1-76:1-76)
10 20 30 40 50 60
pF1KB8 MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 TEIEEELKSLDKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLH
::::::::::::::::
CCDS74 TEIEEELKSLDKEISEGHCV
70 80
485 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 13:04:31 2016 done: Fri Nov 4 13:04:32 2016
Total Scan time: 3.830 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]