FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8456, 485 aa 1>>>pF1KB8456 485 - 485 aa - 485 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.8048+/-0.000855; mu= 6.7446+/- 0.052 mean_var=124.0355+/-24.629, 0's: 0 Z-trim(110.8): 21 B-trim: 5 in 1/52 Lambda= 0.115160 statistics sampled from 11900 (11914) to 11900 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.726), E-opt: 0.2 (0.366), width: 16 Scan time: 3.830 The best scores are: opt bits E(32554) CCDS13746.1 BCL2L13 gene_id:23786|Hs108|chr22 ( 485) 3072 521.4 8.6e-148 CCDS74810.1 BCL2L13 gene_id:23786|Hs108|chr22 ( 509) 2819 479.3 4.1e-135 CCDS59448.1 BCL2L13 gene_id:23786|Hs108|chr22 ( 323) 2039 349.7 2.8e-96 CCDS74811.1 BCL2L13 gene_id:23786|Hs108|chr22 ( 461) 1838 316.3 4.3e-86 CCDS59447.1 BCL2L13 gene_id:23786|Hs108|chr22 ( 171) 817 146.6 2e-35 CCDS74812.1 BCL2L13 gene_id:23786|Hs108|chr22 ( 128) 485 91.4 6.3e-19 CCDS74813.1 BCL2L13 gene_id:23786|Hs108|chr22 ( 80) 462 87.5 5.8e-18 >>CCDS13746.1 BCL2L13 gene_id:23786|Hs108|chr22 (485 aa) initn: 3072 init1: 3072 opt: 3072 Z-score: 2766.8 bits: 521.4 E(32554): 8.6e-148 Smith-Waterman score: 3072; 100.0% identity (100.0% similar) in 485 aa overlap (1-485:1-485) 10 20 30 40 50 60 pF1KB8 MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TEIEEELKSLDKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 TEIEEELKSLDKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 KALQMLLSQPVTYQAFRECTLETTVHASGWNKILVPLVLLRQMLLELTRRGQEPLSALLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 KALQMLLSQPVTYQAFRECTLETTVHASGWNKILVPLVLLRQMLLELTRRGQEPLSALLQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 FGVTYLEDYSAEYIIQQGGWGTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 FGVTYLEDYSAEYIIQQGGWGTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPES 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 PTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 PTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSEN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 NSSNSDIVHVEKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 NSSNSDIVHVEKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 DTEVITVEKSSPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 DTEVITVEKSSPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREES 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 LVEELSPASEKKPVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVAILAVAIGVAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 LVEELSPASEKKPVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVAILAVAIGVAL 430 440 450 460 470 480 pF1KB8 ALRKK ::::: CCDS13 ALRKK >>CCDS74810.1 BCL2L13 gene_id:23786|Hs108|chr22 (509 aa) initn: 2819 init1: 2819 opt: 2819 Z-score: 2539.3 bits: 479.3 E(32554): 4.1e-135 Smith-Waterman score: 2819; 100.0% identity (100.0% similar) in 445 aa overlap (41-485:65-509) 20 30 40 50 60 70 pF1KB8 FHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVKTEIEEELKSL :::::::::::::::::::::::::::::: CCDS74 VGALTAAGGPCRKQLPPPPLSSLLGQGPGPGVQLDIASQSLDQEILLKVKTEIEEELKSL 40 50 60 70 80 90 80 90 100 110 120 130 pF1KB8 DKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLHKALQMLLSQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 DKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLHKALQMLLSQP 100 110 120 130 140 150 140 150 160 170 180 190 pF1KB8 VTYQAFRECTLETTVHASGWNKILVPLVLLRQMLLELTRRGQEPLSALLQFGVTYLEDYS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 VTYQAFRECTLETTVHASGWNKILVPLVLLRQMLLELTRRGQEPLSALLQFGVTYLEDYS 160 170 180 190 200 210 200 210 220 230 240 250 pF1KB8 AEYIIQQGGWGTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 AEYIIQQGGWGTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSE 220 230 240 250 260 270 260 270 280 290 300 310 pF1KB8 SLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSENNSSNSDIVHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 SLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSENNSSNSDIVHV 280 290 300 310 320 330 320 330 340 350 360 370 pF1KB8 EKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 EKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKS 340 350 360 370 380 390 380 390 400 410 420 430 pF1KB8 SPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 SPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASE 400 410 420 430 440 450 440 450 460 470 480 pF1KB8 KKPVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVAILAVAIGVALALRKK ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 KKPVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVAILAVAIGVALALRKK 460 470 480 490 500 >>CCDS59448.1 BCL2L13 gene_id:23786|Hs108|chr22 (323 aa) initn: 2039 init1: 2039 opt: 2039 Z-score: 1842.1 bits: 349.7 E(32554): 2.8e-96 Smith-Waterman score: 2039; 100.0% identity (100.0% similar) in 323 aa overlap (163-485:1-323) 140 150 160 170 180 190 pF1KB8 YQAFRECTLETTVHASGWNKILVPLVLLRQMLLELTRRGQEPLSALLQFGVTYLEDYSAE :::::::::::::::::::::::::::::: CCDS59 MLLELTRRGQEPLSALLQFGVTYLEDYSAE 10 20 30 200 210 220 230 240 250 pF1KB8 YIIQQGGWGTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 YIIQQGGWGTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSESL 40 50 60 70 80 90 260 270 280 290 300 310 pF1KB8 PVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSENNSSNSDIVHVEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 PVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSENNSSNSDIVHVEK 100 110 120 130 140 150 320 330 340 350 360 370 pF1KB8 EEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 EEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSP 160 170 180 190 200 210 380 390 400 410 420 430 pF1KB8 ATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 ATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKK 220 230 240 250 260 270 440 450 460 470 480 pF1KB8 PVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVAILAVAIGVALALRKK ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 PVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVAILAVAIGVALALRKK 280 290 300 310 320 >>CCDS74811.1 BCL2L13 gene_id:23786|Hs108|chr22 (461 aa) initn: 2496 init1: 1789 opt: 1838 Z-score: 1659.1 bits: 316.3 E(32554): 4.3e-86 Smith-Waterman score: 2404; 89.2% identity (89.2% similar) in 445 aa overlap (41-485:65-461) 20 30 40 50 60 70 pF1KB8 FHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVKTEIEEELKSL :::::::::::::::::::::::::::::: CCDS74 VGALTAAGGPCRKQLPPPPLSSLLGQGPGPGVQLDIASQSLDQEILLKVKTEIEEELKSL 40 50 60 70 80 90 80 90 100 110 120 130 pF1KB8 DKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLHKALQMLLSQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 DKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLHKALQMLLSQP 100 110 120 130 140 150 140 150 160 170 180 190 pF1KB8 VTYQAFRECTLETTVHASGWNKILVPLVLLRQMLLELTRRGQEPLSALLQFGVTYLEDYS :::::::::::::::::::::: CCDS74 VTYQAFRECTLETTVHASGWNK-------------------------------------- 160 170 200 210 220 230 240 250 pF1KB8 AEYIIQQGGWGTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSE :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 ----------GTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSE 180 190 200 210 220 260 270 280 290 300 310 pF1KB8 SLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSENNSSNSDIVHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 SLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSENNSSNSDIVHV 230 240 250 260 270 280 320 330 340 350 360 370 pF1KB8 EKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 EKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKS 290 300 310 320 330 340 380 390 400 410 420 430 pF1KB8 SPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 SPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASE 350 360 370 380 390 400 440 450 460 470 480 pF1KB8 KKPVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVAILAVAIGVALALRKK ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 KKPVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVAILAVAIGVALALRKK 410 420 430 440 450 460 >>CCDS59447.1 BCL2L13 gene_id:23786|Hs108|chr22 (171 aa) initn: 813 init1: 813 opt: 817 Z-score: 749.3 bits: 146.6 E(32554): 2e-35 Smith-Waterman score: 817; 91.7% identity (95.2% similar) in 145 aa overlap (1-143:1-145) 10 20 30 40 50 60 pF1KB8 MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TEIEEELKSLDKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS59 TEIEEELKSLDKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLH 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 KALQMLLSQPV--TYQAFRECTLETTVHASGWNKILVPLVLLRQMLLELTRRGQEPLSAL ::::::::: . . . :. :::. CCDS59 KALQMLLSQALCLVLSQRRRNTLESLQKIAMTFTSCPATTLDKSVPQSLQL 130 140 150 160 170 >>CCDS74812.1 BCL2L13 gene_id:23786|Hs108|chr22 (128 aa) initn: 485 init1: 485 opt: 485 Z-score: 453.3 bits: 91.4 E(32554): 6.3e-19 Smith-Waterman score: 485; 95.2% identity (97.6% similar) in 83 aa overlap (1-83:1-83) 10 20 30 40 50 60 pF1KB8 MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TEIEEELKSLDKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLH :::::::::::::::: : ..:: CCDS74 TEIEEELKSLDKEISEDFGASGFATTNAFGIDKTWSRTFERTAAVWRDIPGGLFGRVHHS 70 80 90 100 110 120 >>CCDS74813.1 BCL2L13 gene_id:23786|Hs108|chr22 (80 aa) initn: 462 init1: 462 opt: 462 Z-score: 435.9 bits: 87.5 E(32554): 5.8e-18 Smith-Waterman score: 462; 100.0% identity (100.0% similar) in 76 aa overlap (1-76:1-76) 10 20 30 40 50 60 pF1KB8 MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TEIEEELKSLDKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLH :::::::::::::::: CCDS74 TEIEEELKSLDKEISEGHCV 70 80 485 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 13:04:31 2016 done: Fri Nov 4 13:04:32 2016 Total Scan time: 3.830 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]