FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8460, 252 aa 1>>>pF1KB8460 252 - 252 aa - 252 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2558+/-0.000278; mu= 16.8143+/- 0.017 mean_var=84.0694+/-17.126, 0's: 0 Z-trim(120.1): 9 B-trim: 0 in 0/55 Lambda= 0.139880 statistics sampled from 34825 (34834) to 34825 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.761), E-opt: 0.2 (0.408), width: 16 Scan time: 7.680 The best scores are: opt bits E(85289) NP_065391 (OMIM: 165095) oncostatin-M isoform 1 pr ( 252) 1693 350.5 1.7e-96 NP_001306037 (OMIM: 165095) oncostatin-M isoform 2 ( 231) 1571 325.8 4.1e-89 >>NP_065391 (OMIM: 165095) oncostatin-M isoform 1 prepro (252 aa) initn: 1693 init1: 1693 opt: 1693 Z-score: 1853.4 bits: 350.5 E(85289): 1.7e-96 Smith-Waterman score: 1693; 100.0% identity (100.0% similar) in 252 aa overlap (1-252:1-252) 10 20 30 40 50 60 pF1KB8 MGVLLTQRTLLSLVLALLFPSMASMAAIGSCSKEYRVLLGQLQKQTDLMQDTSRLLDPYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 MGVLLTQRTLLSLVLALLFPSMASMAAIGSCSKEYRVLLGQLQKQTDLMQDTSRLLDPYI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 RIQGLDVPKLREHCRERPGAFPSEETLRGLGRRGFLQTLNATLGCVLHRLADLEQRLPKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 RIQGLDVPKLREHCRERPGAFPSEETLRGLGRRGFLQTLNATLGCVLHRLADLEQRLPKA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QDLERSGLNIEDLEKLQMARPNILGLRNNIYCMAQLLDNSDTAEPTKAGRGASQPPTPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 QDLERSGLNIEDLEKLQMARPNILGLRNNIYCMAQLLDNSDTAEPTKAGRGASQPPTPTP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ASDAFQRKLEGCRFLHGYHRFMHSVGRVFSKWGESPNRSRRHSPHQALRKGVRRTRPSRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 ASDAFQRKLEGCRFLHGYHRFMHSVGRVFSKWGESPNRSRRHSPHQALRKGVRRTRPSRK 190 200 210 220 230 240 250 pF1KB8 GKRLMTRGQLPR :::::::::::: NP_065 GKRLMTRGQLPR 250 >>NP_001306037 (OMIM: 165095) oncostatin-M isoform 2 [Ho (231 aa) initn: 1571 init1: 1571 opt: 1571 Z-score: 1720.8 bits: 325.8 E(85289): 4.1e-89 Smith-Waterman score: 1571; 100.0% identity (100.0% similar) in 231 aa overlap (22-252:1-231) 10 20 30 40 50 60 pF1KB8 MGVLLTQRTLLSLVLALLFPSMASMAAIGSCSKEYRVLLGQLQKQTDLMQDTSRLLDPYI ::::::::::::::::::::::::::::::::::::::: NP_001 MASMAAIGSCSKEYRVLLGQLQKQTDLMQDTSRLLDPYI 10 20 30 70 80 90 100 110 120 pF1KB8 RIQGLDVPKLREHCRERPGAFPSEETLRGLGRRGFLQTLNATLGCVLHRLADLEQRLPKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIQGLDVPKLREHCRERPGAFPSEETLRGLGRRGFLQTLNATLGCVLHRLADLEQRLPKA 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB8 QDLERSGLNIEDLEKLQMARPNILGLRNNIYCMAQLLDNSDTAEPTKAGRGASQPPTPTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QDLERSGLNIEDLEKLQMARPNILGLRNNIYCMAQLLDNSDTAEPTKAGRGASQPPTPTP 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB8 ASDAFQRKLEGCRFLHGYHRFMHSVGRVFSKWGESPNRSRRHSPHQALRKGVRRTRPSRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASDAFQRKLEGCRFLHGYHRFMHSVGRVFSKWGESPNRSRRHSPHQALRKGVRRTRPSRK 160 170 180 190 200 210 250 pF1KB8 GKRLMTRGQLPR :::::::::::: NP_001 GKRLMTRGQLPR 220 230 252 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 13:07:37 2016 done: Fri Nov 4 13:07:39 2016 Total Scan time: 7.680 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]