FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8463, 348 aa 1>>>pF1KB8463 348 - 348 aa - 348 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.2630+/-0.000454; mu= 11.3480+/- 0.028 mean_var=81.9154+/-17.361, 0's: 0 Z-trim(109.2): 81 B-trim: 0 in 0/52 Lambda= 0.141707 statistics sampled from 17330 (17381) to 17330 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.558), E-opt: 0.2 (0.204), width: 16 Scan time: 7.880 The best scores are: opt bits E(85289) NP_055248 (OMIM: 605663) radial spoke head 14 homo ( 348) 2194 458.7 8.3e-129 XP_011528451 (OMIM: 605663) PREDICTED: radial spok ( 398) 1688 355.3 1.3e-97 XP_016884263 (OMIM: 605663) PREDICTED: radial spok ( 402) 1681 353.9 3.5e-97 XP_011528454 (OMIM: 605663) PREDICTED: radial spok ( 402) 1681 353.9 3.5e-97 XP_011528452 (OMIM: 605663) PREDICTED: radial spok ( 402) 1681 353.9 3.5e-97 XP_011528453 (OMIM: 605663) PREDICTED: radial spok ( 402) 1681 353.9 3.5e-97 XP_011528456 (OMIM: 605663) PREDICTED: radial spok ( 334) 1227 261.0 2.6e-69 XP_011528457 (OMIM: 605663) PREDICTED: radial spok ( 270) 779 169.4 8e-42 >>NP_055248 (OMIM: 605663) radial spoke head 14 homolog (348 aa) initn: 2194 init1: 2194 opt: 2194 Z-score: 2433.5 bits: 458.7 E(85289): 8.3e-129 Smith-Waterman score: 2194; 100.0% identity (100.0% similar) in 348 aa overlap (1-348:1-348) 10 20 30 40 50 60 pF1KB8 MAHSQNSLELPININATQITTAYGHRALPKLKEELQSEDLQTRQKALMALCDLMHDPECI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MAHSQNSLELPININATQITTAYGHRALPKLKEELQSEDLQTRQKALMALCDLMHDPECI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 YKAMNIGCMENLKALLKDSNSMVRIKTTEVLHITASHSVGRYAFLEHDIVLALSFLLNDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 YKAMNIGCMENLKALLKDSNSMVRIKTTEVLHITASHSVGRYAFLEHDIVLALSFLLNDP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 SPVCRGNLYKAYMQLVQVPRGAQEIISKGLISSLVWKLQVEVEEEEFQEFILDTLVLCLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 SPVCRGNLYKAYMQLVQVPRGAQEIISKGLISSLVWKLQVEVEEEEFQEFILDTLVLCLQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 EDATEALGSNVVLVLKQKLLSANQNIRSKAARALLNVSISREGKKQVCHFDVIPILVHLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EDATEALGSNVVLVLKQKLLSANQNIRSKAARALLNVSISREGKKQVCHFDVIPILVHLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 KDPVEHVKSNAAGALMFATVITEGKYAALEAQAIGLLLELLHSPMTIARLNATKALTMLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 KDPVEHVKSNAAGALMFATVITEGKYAALEAQAIGLLLELLHSPMTIARLNATKALTMLA 250 260 270 280 290 300 310 320 330 340 pF1KB8 EAPEGRKALQTHVPTFRAMEVETYEKPQVAEALQRAARIAISVIEFKP :::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EAPEGRKALQTHVPTFRAMEVETYEKPQVAEALQRAARIAISVIEFKP 310 320 330 340 >>XP_011528451 (OMIM: 605663) PREDICTED: radial spoke he (398 aa) initn: 1678 init1: 1678 opt: 1688 Z-score: 1873.5 bits: 355.3 E(85289): 1.3e-97 Smith-Waterman score: 1977; 86.8% identity (86.8% similar) in 380 aa overlap (1-330:1-380) 10 20 30 40 50 60 pF1KB8 MAHSQNSLELPININATQITTAYGHRALPKLKEELQSEDLQTRQKALMALCDLMHDPECI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAHSQNSLELPININATQITTAYGHRALPKLKEELQSEDLQTRQKALMALCDLMHDPECI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 YKAMNIGCMENLKALLKDSNSMVRIKTTEVLHITASHSVGRYAFLEHDIVLALSFLLNDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YKAMNIGCMENLKALLKDSNSMVRIKTTEVLHITASHSVGRYAFLEHDIVLALSFLLNDP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 SPVCRGNLYKAYMQLVQVPRGAQEIISKGLISSLVWKLQVEVEEEEFQEFILDTLVLCLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPVCRGNLYKAYMQLVQVPRGAQEIISKGLISSLVWKLQVEVEEEEFQEFILDTLVLCLQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 EDATEALGSNVVLVLKQKLLSANQNIRSKAARALLNVSISREGKKQVCHFDVIPILVHLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDATEALGSNVVLVLKQKLLSANQNIRSKAARALLNVSISREGKKQVCHFDVIPILVHLL 190 200 210 220 230 240 250 260 pF1KB8 KDPVEHVKSNAAGALMFATVITE------------------------------------- ::::::::::::::::::::::: XP_011 KDPVEHVKSNAAGALMFATVITEEMESHYVAQAGLELLGRIRGWMERSQLRPERQEMKRP 250 260 270 280 290 300 270 280 290 300 310 pF1KB8 -------------GKYAALEAQAIGLLLELLHSPMTIARLNATKALTMLAEAPEGRKALQ ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GPGRTQRRCKSPEGKYAALEAQAIGLLLELLHSPMTIARLNATKALTMLAEAPEGRKALQ 310 320 330 340 350 360 320 330 340 pF1KB8 THVPTFRAMEVETYEKPQVAEALQRAARIAISVIEFKP :::::::::::::::::::: XP_011 THVPTFRAMEVETYEKPQVAEALQRAARIAISVIEFKP 370 380 390 >>XP_016884263 (OMIM: 605663) PREDICTED: radial spoke he (402 aa) initn: 1678 init1: 1678 opt: 1681 Z-score: 1865.7 bits: 353.9 E(85289): 3.5e-97 Smith-Waterman score: 1681; 96.8% identity (97.1% similar) in 278 aa overlap (1-278:1-277) 10 20 30 40 50 60 pF1KB8 MAHSQNSLELPININATQITTAYGHRALPKLKEELQSEDLQTRQKALMALCDLMHDPECI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAHSQNSLELPININATQITTAYGHRALPKLKEELQSEDLQTRQKALMALCDLMHDPECI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 YKAMNIGCMENLKALLKDSNSMVRIKTTEVLHITASHSVGRYAFLEHDIVLALSFLLNDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YKAMNIGCMENLKALLKDSNSMVRIKTTEVLHITASHSVGRYAFLEHDIVLALSFLLNDP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 SPVCRGNLYKAYMQLVQVPRGAQEIISKGLISSLVWKLQVEVEEEEFQEFILDTLVLCLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPVCRGNLYKAYMQLVQVPRGAQEIISKGLISSLVWKLQVEVEEEEFQEFILDTLVLCLQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 EDATEALGSNVVLVLKQKLLSANQNIRSKAARALLNVSISREGKKQVCHFDVIPILVHLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDATEALGSNVVLVLKQKLLSANQNIRSKAARALLNVSISREGKKQVCHFDVIPILVHLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 KDPVEHVKSNAAGALMFATVITEGKYAALEAQAIGLLLELLHSPMTIARLNATKALTMLA ::::::::::::::::::::::: . ::: :: : XP_016 KDPVEHVKSNAAGALMFATVITEEMESHYVAQA-GLELLGRIRGWMERSQLRPERQEMKR 250 260 270 280 290 310 320 330 340 pF1KB8 EAPEGRKALQTHVPTFRAMEVETYEKPQVAEALQRAARIAISVIEFKP XP_016 PGPGRTQRREVCGPGGTSHRPAPGAAALPHDHSAPECHQGPYHAGRGPRGPQGPADARAH 300 310 320 330 340 350 >>XP_011528454 (OMIM: 605663) PREDICTED: radial spoke he (402 aa) initn: 1678 init1: 1678 opt: 1681 Z-score: 1865.7 bits: 353.9 E(85289): 3.5e-97 Smith-Waterman score: 1681; 96.8% identity (97.1% similar) in 278 aa overlap (1-278:1-277) 10 20 30 40 50 60 pF1KB8 MAHSQNSLELPININATQITTAYGHRALPKLKEELQSEDLQTRQKALMALCDLMHDPECI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAHSQNSLELPININATQITTAYGHRALPKLKEELQSEDLQTRQKALMALCDLMHDPECI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 YKAMNIGCMENLKALLKDSNSMVRIKTTEVLHITASHSVGRYAFLEHDIVLALSFLLNDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YKAMNIGCMENLKALLKDSNSMVRIKTTEVLHITASHSVGRYAFLEHDIVLALSFLLNDP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 SPVCRGNLYKAYMQLVQVPRGAQEIISKGLISSLVWKLQVEVEEEEFQEFILDTLVLCLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPVCRGNLYKAYMQLVQVPRGAQEIISKGLISSLVWKLQVEVEEEEFQEFILDTLVLCLQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 EDATEALGSNVVLVLKQKLLSANQNIRSKAARALLNVSISREGKKQVCHFDVIPILVHLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDATEALGSNVVLVLKQKLLSANQNIRSKAARALLNVSISREGKKQVCHFDVIPILVHLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 KDPVEHVKSNAAGALMFATVITEGKYAALEAQAIGLLLELLHSPMTIARLNATKALTMLA ::::::::::::::::::::::: . ::: :: : XP_011 KDPVEHVKSNAAGALMFATVITEEMESHYVAQA-GLELLGRIRGWMERSQLRPERQEMKR 250 260 270 280 290 310 320 330 340 pF1KB8 EAPEGRKALQTHVPTFRAMEVETYEKPQVAEALQRAARIAISVIEFKP XP_011 PGPGRTQRREVCGPGGTSHRPAPGAAALPHDHSAPECHQGPYHAGRGPRGPQGPADARAH 300 310 320 330 340 350 >>XP_011528452 (OMIM: 605663) PREDICTED: radial spoke he (402 aa) initn: 1678 init1: 1678 opt: 1681 Z-score: 1865.7 bits: 353.9 E(85289): 3.5e-97 Smith-Waterman score: 1681; 96.8% identity (97.1% similar) in 278 aa overlap (1-278:1-277) 10 20 30 40 50 60 pF1KB8 MAHSQNSLELPININATQITTAYGHRALPKLKEELQSEDLQTRQKALMALCDLMHDPECI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAHSQNSLELPININATQITTAYGHRALPKLKEELQSEDLQTRQKALMALCDLMHDPECI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 YKAMNIGCMENLKALLKDSNSMVRIKTTEVLHITASHSVGRYAFLEHDIVLALSFLLNDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YKAMNIGCMENLKALLKDSNSMVRIKTTEVLHITASHSVGRYAFLEHDIVLALSFLLNDP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 SPVCRGNLYKAYMQLVQVPRGAQEIISKGLISSLVWKLQVEVEEEEFQEFILDTLVLCLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPVCRGNLYKAYMQLVQVPRGAQEIISKGLISSLVWKLQVEVEEEEFQEFILDTLVLCLQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 EDATEALGSNVVLVLKQKLLSANQNIRSKAARALLNVSISREGKKQVCHFDVIPILVHLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDATEALGSNVVLVLKQKLLSANQNIRSKAARALLNVSISREGKKQVCHFDVIPILVHLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 KDPVEHVKSNAAGALMFATVITEGKYAALEAQAIGLLLELLHSPMTIARLNATKALTMLA ::::::::::::::::::::::: . ::: :: : XP_011 KDPVEHVKSNAAGALMFATVITEEMESHYVAQA-GLELLGRIRGWMERSQLRPERQEMKR 250 260 270 280 290 310 320 330 340 pF1KB8 EAPEGRKALQTHVPTFRAMEVETYEKPQVAEALQRAARIAISVIEFKP XP_011 PGPGRTQRREVCGPGGTSHRPAPGAAALPHDHSAPECHQGPYHAGRGPRGPQGPADARAH 300 310 320 330 340 350 >>XP_011528453 (OMIM: 605663) PREDICTED: radial spoke he (402 aa) initn: 1678 init1: 1678 opt: 1681 Z-score: 1865.7 bits: 353.9 E(85289): 3.5e-97 Smith-Waterman score: 1681; 96.8% identity (97.1% similar) in 278 aa overlap (1-278:1-277) 10 20 30 40 50 60 pF1KB8 MAHSQNSLELPININATQITTAYGHRALPKLKEELQSEDLQTRQKALMALCDLMHDPECI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAHSQNSLELPININATQITTAYGHRALPKLKEELQSEDLQTRQKALMALCDLMHDPECI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 YKAMNIGCMENLKALLKDSNSMVRIKTTEVLHITASHSVGRYAFLEHDIVLALSFLLNDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YKAMNIGCMENLKALLKDSNSMVRIKTTEVLHITASHSVGRYAFLEHDIVLALSFLLNDP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 SPVCRGNLYKAYMQLVQVPRGAQEIISKGLISSLVWKLQVEVEEEEFQEFILDTLVLCLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPVCRGNLYKAYMQLVQVPRGAQEIISKGLISSLVWKLQVEVEEEEFQEFILDTLVLCLQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 EDATEALGSNVVLVLKQKLLSANQNIRSKAARALLNVSISREGKKQVCHFDVIPILVHLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDATEALGSNVVLVLKQKLLSANQNIRSKAARALLNVSISREGKKQVCHFDVIPILVHLL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 KDPVEHVKSNAAGALMFATVITEGKYAALEAQAIGLLLELLHSPMTIARLNATKALTMLA ::::::::::::::::::::::: . ::: :: : XP_011 KDPVEHVKSNAAGALMFATVITEEMESHYVAQA-GLELLGRIRGWMERSQLRPERQEMKR 250 260 270 280 290 310 320 330 340 pF1KB8 EAPEGRKALQTHVPTFRAMEVETYEKPQVAEALQRAARIAISVIEFKP XP_011 PGPGRTQRREVCGPGGTSHRPAPGAAALPHDHSAPECHQGPYHAGRGPRGPQGPADARAH 300 310 320 330 340 350 >>XP_011528456 (OMIM: 605663) PREDICTED: radial spoke he (334 aa) initn: 1224 init1: 1224 opt: 1227 Z-score: 1365.3 bits: 261.0 E(85289): 2.6e-69 Smith-Waterman score: 1227; 95.7% identity (96.2% similar) in 210 aa overlap (69-278:1-209) 40 50 60 70 80 90 pF1KB8 DLQTRQKALMALCDLMHDPECIYKAMNIGCMENLKALLKDSNSMVRIKTTEVLHITASHS :::::::::::::::::::::::::::::: XP_011 MENLKALLKDSNSMVRIKTTEVLHITASHS 10 20 30 100 110 120 130 140 150 pF1KB8 VGRYAFLEHDIVLALSFLLNDPSPVCRGNLYKAYMQLVQVPRGAQEIISKGLISSLVWKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGRYAFLEHDIVLALSFLLNDPSPVCRGNLYKAYMQLVQVPRGAQEIISKGLISSLVWKL 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB8 QVEVEEEEFQEFILDTLVLCLQEDATEALGSNVVLVLKQKLLSANQNIRSKAARALLNVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVEVEEEEFQEFILDTLVLCLQEDATEALGSNVVLVLKQKLLSANQNIRSKAARALLNVS 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB8 ISREGKKQVCHFDVIPILVHLLKDPVEHVKSNAAGALMFATVITEGKYAALEAQAIGLLL ::::::::::::::::::::::::::::::::::::::::::::: . ::: :: : XP_011 ISREGKKQVCHFDVIPILVHLLKDPVEHVKSNAAGALMFATVITEEMESHYVAQA-GLEL 160 170 180 190 200 280 290 300 310 320 330 pF1KB8 ELLHSPMTIARLNATKALTMLAEAPEGRKALQTHVPTFRAMEVETYEKPQVAEALQRAAR XP_011 LGRIRGWMERSQLRPERQEMKRPGPGRTQRREVCGPGGTSHRPAPGAAALPHDHSAPECH 210 220 230 240 250 260 >>XP_011528457 (OMIM: 605663) PREDICTED: radial spoke he (270 aa) initn: 776 init1: 776 opt: 779 Z-score: 871.8 bits: 169.4 E(85289): 8e-42 Smith-Waterman score: 779; 89.7% identity (91.8% similar) in 146 aa overlap (133-278:1-145) 110 120 130 140 150 160 pF1KB8 AFLEHDIVLALSFLLNDPSPVCRGNLYKAYMQLVQVPRGAQEIISKGLISSLVWKLQVEV :: . . :::::::::::::::::::::: XP_011 MQTLTIYTGAQEIISKGLISSLVWKLQVEV 10 20 30 170 180 190 200 210 220 pF1KB8 EEEEFQEFILDTLVLCLQEDATEALGSNVVLVLKQKLLSANQNIRSKAARALLNVSISRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EEEEFQEFILDTLVLCLQEDATEALGSNVVLVLKQKLLSANQNIRSKAARALLNVSISRE 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB8 GKKQVCHFDVIPILVHLLKDPVEHVKSNAAGALMFATVITEGKYAALEAQAIGLLLELLH ::::::::::::::::::::::::::::::::::::::::: . ::: :: : XP_011 GKKQVCHFDVIPILVHLLKDPVEHVKSNAAGALMFATVITEEMESHYVAQA-GLELLGRI 100 110 120 130 140 290 300 310 320 330 340 pF1KB8 SPMTIARLNATKALTMLAEAPEGRKALQTHVPTFRAMEVETYEKPQVAEALQRAARIAIS XP_011 RGWMERSQLRPERQEMKRPGPGRTQRREVCGPGGTSHRPAPGAAALPHDHSAPECHQGPY 150 160 170 180 190 200 348 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 13:09:19 2016 done: Fri Nov 4 13:09:20 2016 Total Scan time: 7.880 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]