FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8466, 418 aa 1>>>pF1KB8466 418 - 418 aa - 418 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.0197+/-0.000342; mu= 10.3574+/- 0.022 mean_var=152.2990+/-31.746, 0's: 0 Z-trim(120.1): 727 B-trim: 3113 in 2/52 Lambda= 0.103926 statistics sampled from 34030 (34860) to 34030 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.409), width: 16 Scan time: 8.950 The best scores are: opt bits E(85289) XP_016884413 (OMIM: 182453) PREDICTED: somatostati ( 418) 2787 429.5 7.6e-120 XP_005261778 (OMIM: 182453) PREDICTED: somatostati ( 418) 2787 429.5 7.6e-120 XP_011528651 (OMIM: 182453) PREDICTED: somatostati ( 418) 2787 429.5 7.6e-120 NP_001042 (OMIM: 182453) somatostatin receptor typ ( 418) 2787 429.5 7.6e-120 XP_006724374 (OMIM: 182453) PREDICTED: somatostati ( 418) 2787 429.5 7.6e-120 XP_016884412 (OMIM: 182453) PREDICTED: somatostati ( 418) 2787 429.5 7.6e-120 NP_001265616 (OMIM: 182453) somatostatin receptor ( 418) 2787 429.5 7.6e-120 NP_001166031 (OMIM: 182455) somatostatin receptor ( 364) 1322 209.8 9.1e-54 NP_001044 (OMIM: 182455) somatostatin receptor typ ( 364) 1322 209.8 9.1e-54 NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 1192 190.3 6.8e-48 NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388) 1051 169.2 1.6e-41 NP_001040 (OMIM: 182451) somatostatin receptor typ ( 391) 1049 168.9 2e-41 NP_005276 (OMIM: 600730) neuropeptides B/W recepto ( 328) 812 133.3 8.8e-31 NP_000902 (OMIM: 165195) delta-type opioid recepto ( 372) 800 131.5 3.4e-30 NP_005277 (OMIM: 600731) neuropeptides B/W recepto ( 333) 791 130.1 7.9e-30 NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370) 787 129.6 1.3e-29 XP_016883343 (OMIM: 602548) PREDICTED: nociceptin ( 370) 787 129.6 1.3e-29 NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370) 787 129.6 1.3e-29 NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370) 787 129.6 1.3e-29 XP_016883342 (OMIM: 602548) PREDICTED: nociceptin ( 388) 787 129.6 1.3e-29 XP_011527130 (OMIM: 602548) PREDICTED: nociceptin ( 388) 787 129.6 1.3e-29 XP_016883341 (OMIM: 602548) PREDICTED: nociceptin ( 388) 787 129.6 1.3e-29 NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399) 787 129.6 1.4e-29 NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389) 776 128.0 4.2e-29 NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392) 776 128.0 4.2e-29 NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397) 776 128.0 4.3e-29 NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400) 776 128.0 4.3e-29 NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403) 776 128.0 4.3e-29 NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406) 776 128.0 4.3e-29 NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414) 776 128.0 4.4e-29 NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418) 776 128.0 4.4e-29 NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420) 776 128.0 4.5e-29 NP_001008505 (OMIM: 600018) mu-type opioid recepto ( 446) 776 128.0 4.6e-29 NP_001272453 (OMIM: 600018) mu-type opioid recepto ( 493) 776 128.0 5e-29 NP_001138751 (OMIM: 600018) mu-type opioid recepto ( 493) 776 128.0 5e-29 NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 769 126.9 8.6e-29 NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 769 126.9 9e-29 NP_001305783 (OMIM: 602548) nociceptin receptor is ( 365) 738 122.2 2.1e-27 XP_016883344 (OMIM: 602548) PREDICTED: nociceptin ( 365) 738 122.2 2.1e-27 NP_001138753 (OMIM: 600018) mu-type opioid recepto ( 319) 664 111.1 4.1e-24 NP_001305784 (OMIM: 602548) nociceptin receptor is ( 341) 662 110.8 5.3e-24 NP_005288 (OMIM: 601751) melanin-concentrating hor ( 422) 659 110.4 8.5e-24 NP_001272456 (OMIM: 600018) mu-type opioid recepto ( 292) 654 109.5 1.1e-23 NP_001272455 (OMIM: 600018) mu-type opioid recepto ( 300) 654 109.6 1.1e-23 XP_016866395 (OMIM: 600018) PREDICTED: mu-type opi ( 300) 654 109.6 1.1e-23 NP_001138759 (OMIM: 600018) mu-type opioid recepto ( 300) 654 109.6 1.1e-23 NP_001138752 (OMIM: 600018) mu-type opioid recepto ( 300) 654 109.6 1.1e-23 NP_001272457 (OMIM: 600018) mu-type opioid recepto ( 314) 654 109.6 1.2e-23 XP_011534155 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 654 109.6 1.2e-23 XP_011534158 (OMIM: 600018) PREDICTED: mu-type opi ( 346) 654 109.6 1.2e-23 >>XP_016884413 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 2787 init1: 2787 opt: 2787 Z-score: 2272.6 bits: 429.5 E(85289): 7.6e-120 Smith-Waterman score: 2787; 100.0% identity (100.0% similar) in 418 aa overlap (1-418:1-418) 10 20 30 40 50 60 pF1KB8 MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 AVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 FSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 WAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEE 310 320 330 340 350 360 370 380 390 400 410 pF1KB8 SREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL 370 380 390 400 410 >>XP_005261778 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 2787 init1: 2787 opt: 2787 Z-score: 2272.6 bits: 429.5 E(85289): 7.6e-120 Smith-Waterman score: 2787; 100.0% identity (100.0% similar) in 418 aa overlap (1-418:1-418) 10 20 30 40 50 60 pF1KB8 MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 AVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 FSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 WAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 WAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEE 310 320 330 340 350 360 370 380 390 400 410 pF1KB8 SREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL 370 380 390 400 410 >>XP_011528651 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 2787 init1: 2787 opt: 2787 Z-score: 2272.6 bits: 429.5 E(85289): 7.6e-120 Smith-Waterman score: 2787; 100.0% identity (100.0% similar) in 418 aa overlap (1-418:1-418) 10 20 30 40 50 60 pF1KB8 MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 AVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 FSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 WAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEE 310 320 330 340 350 360 370 380 390 400 410 pF1KB8 SREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL 370 380 390 400 410 >>NP_001042 (OMIM: 182453) somatostatin receptor type 3 (418 aa) initn: 2787 init1: 2787 opt: 2787 Z-score: 2272.6 bits: 429.5 E(85289): 7.6e-120 Smith-Waterman score: 2787; 100.0% identity (100.0% similar) in 418 aa overlap (1-418:1-418) 10 20 30 40 50 60 pF1KB8 MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 AVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 FSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 WAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEE 310 320 330 340 350 360 370 380 390 400 410 pF1KB8 SREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL 370 380 390 400 410 >>XP_006724374 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 2787 init1: 2787 opt: 2787 Z-score: 2272.6 bits: 429.5 E(85289): 7.6e-120 Smith-Waterman score: 2787; 100.0% identity (100.0% similar) in 418 aa overlap (1-418:1-418) 10 20 30 40 50 60 pF1KB8 MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 AVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 FSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 WAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEE 310 320 330 340 350 360 370 380 390 400 410 pF1KB8 SREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL 370 380 390 400 410 >>XP_016884412 (OMIM: 182453) PREDICTED: somatostatin re (418 aa) initn: 2787 init1: 2787 opt: 2787 Z-score: 2272.6 bits: 429.5 E(85289): 7.6e-120 Smith-Waterman score: 2787; 100.0% identity (100.0% similar) in 418 aa overlap (1-418:1-418) 10 20 30 40 50 60 pF1KB8 MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 AVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 FSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 WAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEE 310 320 330 340 350 360 370 380 390 400 410 pF1KB8 SREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL 370 380 390 400 410 >>NP_001265616 (OMIM: 182453) somatostatin receptor type (418 aa) initn: 2787 init1: 2787 opt: 2787 Z-score: 2272.6 bits: 429.5 E(85289): 7.6e-120 Smith-Waterman score: 2787; 100.0% identity (100.0% similar) in 418 aa overlap (1-418:1-418) 10 20 30 40 50 60 pF1KB8 MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 AVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 FSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 WAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEE 310 320 330 340 350 360 370 380 390 400 410 pF1KB8 SREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL 370 380 390 400 410 >>NP_001166031 (OMIM: 182455) somatostatin receptor type (364 aa) initn: 1018 init1: 656 opt: 1322 Z-score: 1086.3 bits: 209.8 E(85289): 9.1e-54 Smith-Waterman score: 1322; 56.6% identity (79.1% similar) in 369 aa overlap (1-365:1-357) 10 20 30 40 50 pF1KB8 MDMLHPSSVSTTSEPENASSAWPPDATLGNVS---AGPSPAGLAVSGVLIPLVYLVVCVV :. : :.:. . :::: : :. :. . .::.:.. : .::.:..::.::.. NP_001 MEPLFPASTPSW----NASS--PGAASGGGDNRTLVGPAPSAGA-RAVLVPVLYLLVCAA 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 GLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCR :: ::.:::::::: . .:::.::::::.:: :.::::::::.::: :.:::: ..:: NP_001 GLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCR 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 LVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLP :::..::.:::::.::::::::::::::::: ::::: ::. .:::.:: : . :: NP_001 LVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLP 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 VVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAG ..::. : .: .::. .::::.. : : ::::::.::::.:::::::::::::::::.:: NP_001 LLVFADVQEG-GTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAG 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 RRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFL :: .: ::: :::.:::::..:: .:. ::.::...::::.. ::.::: ::::. NP_001 VRV---GCVRRR-SERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFF 240 250 260 270 280 300 310 320 330 340 350 pF1KB8 VVALPYANSCANPILYGFLSYRFKQGFRRVL-LRPSRRVRSQEPTVGPPEKTEEEDEEEE :: : ::::::::.:::::: :.:.:..:: :: . ... . : :.. ....: NP_001 VVILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATP 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB8 DGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRIS .... .: NP_001 PAHRAAANGLMQTSKL 350 360 >>NP_001044 (OMIM: 182455) somatostatin receptor type 5 (364 aa) initn: 1018 init1: 656 opt: 1322 Z-score: 1086.3 bits: 209.8 E(85289): 9.1e-54 Smith-Waterman score: 1322; 56.6% identity (79.1% similar) in 369 aa overlap (1-365:1-357) 10 20 30 40 50 pF1KB8 MDMLHPSSVSTTSEPENASSAWPPDATLGNVS---AGPSPAGLAVSGVLIPLVYLVVCVV :. : :.:. . :::: : :. :. . .::.:.. : .::.:..::.::.. NP_001 MEPLFPASTPSW----NASS--PGAASGGGDNRTLVGPAPSAGA-RAVLVPVLYLLVCAA 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 GLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCR :: ::.:::::::: . .:::.::::::.:: :.::::::::.::: :.:::: ..:: NP_001 GLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCR 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 LVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLP :::..::.:::::.::::::::::::::::: ::::: ::. .:::.:: : . :: NP_001 LVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLP 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 VVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAG ..::. : .: .::. .::::.. : : ::::::.::::.:::::::::::::::::.:: NP_001 LLVFADVQEG-GTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAG 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 RRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFL :: .: ::: :::.:::::..:: .:. ::.::...::::.. ::.::: ::::. NP_001 VRV---GCVRRR-SERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFF 240 250 260 270 280 300 310 320 330 340 350 pF1KB8 VVALPYANSCANPILYGFLSYRFKQGFRRVL-LRPSRRVRSQEPTVGPPEKTEEEDEEEE :: : ::::::::.:::::: :.:.:..:: :: . ... . : :.. ....: NP_001 VVILSYANSCANPVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATP 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB8 DGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRIS .... .: NP_001 PAHRAAANGLMQTSKL 350 360 >>NP_001041 (OMIM: 182452) somatostatin receptor type 2 (369 aa) initn: 914 init1: 914 opt: 1192 Z-score: 980.9 bits: 190.3 E(85289): 6.8e-48 Smith-Waterman score: 1192; 53.2% identity (78.8% similar) in 325 aa overlap (14-328:6-327) 10 20 30 40 50 pF1KB8 MDMLHPSSVSTTSEPENASSAW---PPDATLGNVSAGPS----PAGLAVSGVLIPLVYLV :: :.: .: : : . . ::.. : : .:.... ..:.: NP_001 MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFV 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 VCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGS ::..:: ::.:::::.::.. ..::.::::::.::::::::::::: : :: .::::. NP_001 VCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 LMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAV .::.::.:::::::::::::::::.::::::::: .::.:: .:. .. ::: .: . NP_001 AICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLL 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 VVLPVVVFSGVPR---GMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIV :.::.....:. : :.: ..:: ..:: .:::::: :::. :: .::::::.:. NP_001 VILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFII 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 VKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPA .::.:.: :: . ..:..::..::::: :::.:..::.:::..:. .: . :: NP_001 IKVKSSGIRV---GSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPA 240 250 260 270 280 300 310 320 330 340 350 pF1KB8 FFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEE . :.. .::.: :::::::::::.::: ::..:. :: NP_001 LKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSR 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB8 EDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKS NP_001 LNETTETQRTLLNGDLQTSI 350 360 418 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 13:11:14 2016 done: Fri Nov 4 13:11:16 2016 Total Scan time: 8.950 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]