FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8467, 449 aa 1>>>pF1KB8467 449 - 449 aa - 449 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9757+/-0.00101; mu= 19.1444+/- 0.060 mean_var=61.5016+/-12.026, 0's: 0 Z-trim(103.7): 38 B-trim: 4 in 1/49 Lambda= 0.163543 statistics sampled from 7479 (7515) to 7479 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.614), E-opt: 0.2 (0.231), width: 16 Scan time: 2.760 The best scores are: opt bits E(32554) CCDS13751.1 TUBA8 gene_id:51807|Hs108|chr22 ( 449) 3014 720.0 1.2e-207 CCDS8782.1 TUBA1C gene_id:84790|Hs108|chr12 ( 449) 2783 665.5 3e-191 CCDS2438.1 TUBA4A gene_id:7277|Hs108|chr2 ( 448) 2782 665.3 3.5e-191 CCDS33290.1 TUBA3D gene_id:113457|Hs108|chr2 ( 450) 2781 665.0 4.2e-191 CCDS9284.1 TUBA3C gene_id:7278|Hs108|chr13 ( 450) 2781 665.0 4.2e-191 CCDS76556.1 TUBA1C gene_id:84790|Hs108|chr12 ( 519) 2776 663.9 1.1e-190 CCDS31792.1 TUBA1B gene_id:10376|Hs108|chr12 ( 451) 2774 663.4 1.3e-190 CCDS58227.1 TUBA1A gene_id:7846|Hs108|chr12 ( 451) 2772 662.9 1.8e-190 CCDS8781.1 TUBA1A gene_id:7846|Hs108|chr12 ( 451) 2772 662.9 1.8e-190 CCDS2158.1 TUBA3E gene_id:112714|Hs108|chr2 ( 450) 2727 652.3 2.9e-187 CCDS63131.1 TUBA4A gene_id:7277|Hs108|chr2 ( 433) 2679 641.0 7.1e-184 CCDS54495.1 TUBA8 gene_id:51807|Hs108|chr22 ( 383) 2553 611.2 5.7e-175 CCDS58226.1 TUBA1A gene_id:7846|Hs108|chr12 ( 416) 2541 608.4 4.4e-174 CCDS7066.2 TUBAL3 gene_id:79861|Hs108|chr10 ( 446) 2305 552.7 2.7e-157 CCDS53491.1 TUBAL3 gene_id:79861|Hs108|chr10 ( 406) 2095 503.2 2e-142 CCDS4687.1 TUBB gene_id:203068|Hs108|chr6 ( 444) 1262 306.6 3.2e-83 CCDS7039.1 TUBB4B gene_id:10383|Hs108|chr9 ( 445) 1251 304.0 1.9e-82 CCDS4484.1 TUBB2A gene_id:7280|Hs108|chr6 ( 445) 1240 301.4 1.2e-81 CCDS10988.1 TUBB3 gene_id:10381|Hs108|chr16 ( 450) 1239 301.2 1.4e-81 CCDS12168.1 TUBB4A gene_id:10382|Hs108|chr19 ( 444) 1238 301.0 1.6e-81 CCDS4485.1 TUBB2B gene_id:347733|Hs108|chr6 ( 445) 1238 301.0 1.6e-81 CCDS11858.1 TUBB6 gene_id:84617|Hs108|chr18 ( 446) 1235 300.3 2.7e-81 CCDS7051.1 TUBB8 gene_id:347688|Hs108|chr10 ( 444) 1220 296.7 3.1e-80 CCDS13475.1 TUBB1 gene_id:81027|Hs108|chr20 ( 451) 1186 288.7 8.1e-78 CCDS78124.1 TUBB gene_id:203068|Hs108|chr6 ( 372) 1058 258.5 8.5e-69 CCDS56012.1 TUBB3 gene_id:10381|Hs108|chr16 ( 378) 1053 257.3 2e-68 CCDS11433.1 TUBG1 gene_id:7283|Hs108|chr17 ( 451) 799 197.4 2.5e-50 CCDS32658.1 TUBG2 gene_id:27175|Hs108|chr17 ( 451) 792 195.7 7.8e-50 CCDS5100.1 TUBE1 gene_id:51175|Hs108|chr6 ( 475) 456 116.5 6e-26 CCDS54154.1 TUBD1 gene_id:51174|Hs108|chr17 ( 396) 400 103.2 4.9e-22 CCDS11620.1 TUBD1 gene_id:51174|Hs108|chr17 ( 453) 400 103.3 5.4e-22 CCDS54153.1 TUBD1 gene_id:51174|Hs108|chr17 ( 398) 387 100.2 4.1e-21 CCDS54152.1 TUBD1 gene_id:51174|Hs108|chr17 ( 351) 379 98.2 1.4e-20 CCDS77153.1 TUBB6 gene_id:84617|Hs108|chr18 ( 104) 245 66.3 1.7e-11 >>CCDS13751.1 TUBA8 gene_id:51807|Hs108|chr22 (449 aa) initn: 3014 init1: 3014 opt: 3014 Z-score: 3841.5 bits: 720.0 E(32554): 1.2e-207 Smith-Waterman score: 3014; 100.0% identity (100.0% similar) in 449 aa overlap (1-449:1-449) 10 20 30 40 50 60 pF1KB8 MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 HVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 RIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 QMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 370 380 390 400 410 420 430 440 pF1KB8 AREDLAALEKDYEEVGTDSFEEENEGEEF ::::::::::::::::::::::::::::: CCDS13 AREDLAALEKDYEEVGTDSFEEENEGEEF 430 440 >>CCDS8782.1 TUBA1C gene_id:84790|Hs108|chr12 (449 aa) initn: 2783 init1: 2783 opt: 2783 Z-score: 3547.0 bits: 665.5 E(32554): 3e-191 Smith-Waterman score: 2783; 89.8% identity (97.1% similar) in 449 aa overlap (1-449:1-449) 10 20 30 40 50 60 pF1KB8 MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGK ::::::.::::::::::::::::.::::::: :: . .. . . ::::.::::::: :: CCDS87 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLD ::::::..::::::.::::.:::::::::::::::::::::::::::::.::: :::::: CCDS87 HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTA :::::.: :.::::::.:::::::::::::::::::::.::::::::::.:::::::::: CCDS87 RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNS :::::::::::::::::::::::::::::.::::.:::::::::::.:::::..:::: . CCDS87 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLTVAEITNACFEPAN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPP ::::::::::::::::.::::::::::::.:::.:::::::::::::::::::::::::: CCDS87 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: CCDS87 TVVPGGDLAKVQRAVCMLSNTTAVAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 370 380 390 400 410 420 430 440 pF1KB8 AREDLAALEKDYEEVGTDSFEEENEGEEF ::::.:::::::::::.:: . :.::::. CCDS87 AREDMAALEKDYEEVGADSADGEDEGEEY 430 440 >>CCDS2438.1 TUBA4A gene_id:7277|Hs108|chr2 (448 aa) initn: 2782 init1: 2782 opt: 2782 Z-score: 3545.7 bits: 665.3 E(32554): 3.5e-191 Smith-Waterman score: 2782; 90.0% identity (96.4% similar) in 448 aa overlap (1-448:1-448) 10 20 30 40 50 60 pF1KB8 MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGK :::::::::::::::.:::::::.::::::: :: . .. . . :::::::: ::: :: CCDS24 MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLD ::::::..::::::.::.: : :::::::::::::::::::::::::::.::: :: ::: CCDS24 HVPRAVFVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTA :::::.: :.::::::.:::::::::::::::::::::.::::::::::.:::::::::: CCDS24 RIRKLSDQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNS :::::::::::::::::::::::::::::.::::.:::::::::::::::::..:::: . CCDS24 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPP ::::::::::::::::.::::::::::::.:::::::::.:::::::::::::::::::: CCDS24 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS24 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 370 380 390 400 410 420 430 440 pF1KB8 AREDLAALEKDYEEVGTDSFEEENEGEEF ::::.::::::::::: ::.:.:.:::: CCDS24 AREDMAALEKDYEEVGIDSYEDEDEGEE 430 440 >>CCDS33290.1 TUBA3D gene_id:113457|Hs108|chr2 (450 aa) initn: 2768 init1: 2768 opt: 2781 Z-score: 3544.4 bits: 665.0 E(32554): 4.2e-191 Smith-Waterman score: 2781; 90.7% identity (96.9% similar) in 450 aa overlap (1-449:1-450) 10 20 30 40 50 60 pF1KB8 MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGK ::::::.::::::::::::::::.::::::: :: . .. . . ::::.::::::: :: CCDS33 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLD ::::::..:::::::::::.:::::::::::::::::::::::::::::.::: .::::: CCDS33 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTA :::::.: :.:::::::::::::::::::.::::::::.::::::::::::::::::::: CCDS33 RIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: CCDS33 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNS :::::::::::::::::::::::::::::.::::.:::::::::::::::::..:::: . CCDS33 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPP :::::::::::::::::::::::::::::.:::.:::::::::::::::::::::::::: CCDS33 QMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS33 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 370 380 390 400 410 420 430 440 pF1KB8 AREDLAALEKDYEEVGTDSFEEE-NEGEEF ::::::::::::::::.:: : : .::::. CCDS33 AREDLAALEKDYEEVGVDSVEAEAEEGEEY 430 440 450 >>CCDS9284.1 TUBA3C gene_id:7278|Hs108|chr13 (450 aa) initn: 2768 init1: 2768 opt: 2781 Z-score: 3544.4 bits: 665.0 E(32554): 4.2e-191 Smith-Waterman score: 2781; 90.7% identity (96.9% similar) in 450 aa overlap (1-449:1-450) 10 20 30 40 50 60 pF1KB8 MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGK ::::::.::::::::::::::::.::::::: :: . .. . . ::::.::::::: :: CCDS92 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLD ::::::..:::::::::::.:::::::::::::::::::::::::::::.::: .::::: CCDS92 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTA :::::.: :.:::::::::::::::::::.::::::::.::::::::::::::::::::: CCDS92 RIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: CCDS92 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNS :::::::::::::::::::::::::::::.::::.:::::::::::::::::..:::: . CCDS92 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPP :::::::::::::::::::::::::::::.:::.:::::::::::::::::::::::::: CCDS92 QMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS92 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 370 380 390 400 410 420 430 440 pF1KB8 AREDLAALEKDYEEVGTDSFEEE-NEGEEF ::::::::::::::::.:: : : .::::. CCDS92 AREDLAALEKDYEEVGVDSVEAEAEEGEEY 430 440 450 >>CCDS76556.1 TUBA1C gene_id:84790|Hs108|chr12 (519 aa) initn: 2776 init1: 2776 opt: 2776 Z-score: 3537.1 bits: 663.9 E(32554): 1.1e-190 Smith-Waterman score: 2776; 89.7% identity (97.1% similar) in 448 aa overlap (2-449:72-519) 10 20 30 pF1KB8 MRECISVHVGQAGVQIGNACWELFCLEHGIQ :::::.::::::::::::::::.::::::: CCDS76 IYFTRTLQLPAPFNTCTSSKSRGEPGCDSKRECISIHVGQAGVQIGNACWELYCLEHGIQ 50 60 70 80 90 100 40 50 60 70 80 90 pF1KB8 ADGTFDAQASKINDDDSFTTFFSETGNGKHVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQ :: . .. . . ::::.::::::: ::::::::..::::::.::::.::::::::::: CCDS76 PDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQ 110 120 130 140 150 160 100 110 120 130 140 150 pF1KB8 LITGKEDAANNYARGHYTVGKESIDLVLDRIRKLTDACSGLQGFLIFHSFGGGTGSGFTS ::::::::::::::::::.::: :::::::::::.: :.::::::.:::::::::::::: CCDS76 LITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTS 170 180 190 200 210 220 160 170 180 190 200 210 pF1KB8 LLMERLSLDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYD :::::::.::::::::::.::::::::::::::::::::::::::::::::::::::::: CCDS76 LLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYD 230 240 250 260 270 280 220 230 240 250 260 270 pF1KB8 ICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVT ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.: CCDS76 ICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLAT 290 300 310 320 330 340 280 290 300 310 320 330 pF1KB8 YAPIISAEKAYHEQLSVAEITSSCFEPNSQMVKCDPRHGKYMACCMLYRGDVVPKDVNVA :::.:::::::::::.:::::..:::: .::::::::::::::::.::::::::::::.: CCDS76 YAPVISAEKAYHEQLTVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAA 350 360 370 380 390 400 340 350 360 370 380 390 pF1KB8 IAAIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARL ::.:::::::::::::::::::::::::::::::::::::::::::::::::.::::::: CCDS76 IATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAVAEAWARL 410 420 430 440 450 460 400 410 420 430 440 pF1KB8 DHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGTDSFEEENEGEEF :::::::::::::::::::::::::::::::::.:::::::::::.:: . :.::::. CCDS76 DHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGADSADGEDEGEEY 470 480 490 500 510 >>CCDS31792.1 TUBA1B gene_id:10376|Hs108|chr12 (451 aa) initn: 2767 init1: 2767 opt: 2774 Z-score: 3535.5 bits: 663.4 E(32554): 1.3e-190 Smith-Waterman score: 2774; 89.8% identity (96.7% similar) in 451 aa overlap (1-449:1-451) 10 20 30 40 50 60 pF1KB8 MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGK ::::::.::::::::::::::::.::::::: :: . .. . . ::::.::::::: :: CCDS31 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLD ::::::..::::::.::::.:::::::::::::::::::::::::::::.::: :::::: CCDS31 HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTA :::::.: :.::::::.:::::::::::::::::::::.::::::::::.:::::::::: CCDS31 RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNS :::::::::::::::::::::::::::::.::::.:::::::::::::::::..:::: . CCDS31 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPP ::::::::::::::::.::::::::::::.:::.:::::.:::::::::::::::::::: CCDS31 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS31 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 370 380 390 400 410 420 430 440 pF1KB8 AREDLAALEKDYEEVGTDSFEEENE--GEEF ::::.:::::::::::.:: : :.: :::. CCDS31 AREDMAALEKDYEEVGVDSVEGEGEEEGEEY 430 440 450 >>CCDS58227.1 TUBA1A gene_id:7846|Hs108|chr12 (451 aa) initn: 2765 init1: 2765 opt: 2772 Z-score: 3532.9 bits: 662.9 E(32554): 1.8e-190 Smith-Waterman score: 2772; 89.8% identity (96.7% similar) in 451 aa overlap (1-449:1-451) 10 20 30 40 50 60 pF1KB8 MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGK ::::::.::::::::::::::::.::::::: :: . .. . . ::::.::::::: :: CCDS58 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLD ::::::..::::::.::::.:::::::::::::::::::::::::::::.::: :::::: CCDS58 HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTA :::::.: :.::::::.:::::::::::::::::::::.::::::::::.:::::::::: CCDS58 RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: CCDS58 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNS :::::::::::::::::::::::::::::.::::.:::::::::::::::::..:::: . CCDS58 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPP ::::::::::::::::.::::::::::::.:::.:::::::::::::::::::::::::: CCDS58 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 370 380 390 400 410 420 430 440 pF1KB8 AREDLAALEKDYEEVGTDSFEEENE--GEEF ::::.:::::::::::.:: : :.: :::. CCDS58 AREDMAALEKDYEEVGVDSVEGEGEEEGEEY 430 440 450 >>CCDS8781.1 TUBA1A gene_id:7846|Hs108|chr12 (451 aa) initn: 2765 init1: 2765 opt: 2772 Z-score: 3532.9 bits: 662.9 E(32554): 1.8e-190 Smith-Waterman score: 2772; 89.8% identity (96.7% similar) in 451 aa overlap (1-449:1-451) 10 20 30 40 50 60 pF1KB8 MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGK ::::::.::::::::::::::::.::::::: :: . .. . . ::::.::::::: :: CCDS87 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLD ::::::..::::::.::::.:::::::::::::::::::::::::::::.::: :::::: CCDS87 HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTA :::::.: :.::::::.:::::::::::::::::::::.::::::::::.:::::::::: CCDS87 RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: CCDS87 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNS :::::::::::::::::::::::::::::.::::.:::::::::::::::::..:::: . CCDS87 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPP ::::::::::::::::.::::::::::::.:::.:::::::::::::::::::::::::: CCDS87 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS87 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 370 380 390 400 410 420 430 440 pF1KB8 AREDLAALEKDYEEVGTDSFEEENE--GEEF ::::.:::::::::::.:: : :.: :::. CCDS87 AREDMAALEKDYEEVGVDSVEGEGEEEGEEY 430 440 450 >>CCDS2158.1 TUBA3E gene_id:112714|Hs108|chr2 (450 aa) initn: 2721 init1: 2721 opt: 2727 Z-score: 3475.6 bits: 652.3 E(32554): 2.9e-187 Smith-Waterman score: 2727; 89.3% identity (96.0% similar) in 450 aa overlap (1-449:1-450) 10 20 30 40 50 60 pF1KB8 MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGK ::::::.::::::::::::::::.::::::: :: . .. . . ::::.::::::: :: CCDS21 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLD ::::::..:::::::::::.::::::::::::::::::::.::::::::.::: .::::: CCDS21 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAASNYARGHYTIGKEIVDLVLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTA :::::.: :.:::::::::::::::::::.::::::::.::.:::::::::::::::::: CCDS21 RIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYSKKSKLEFAIYPAPQVSTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: CCDS21 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNS :::::::::::::::::::::::::::::.::::.:::::::::::::::::..:::: . CCDS21 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPP :::::::::::::::::::::::::::::.:::.:::::::::::::::::::::::::: CCDS21 QMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE ::::::::::::::::::::::::::::::: ::::::::: :::::::::::::::::: CCDS21 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLVHKFDLMYAKWAFVHWYVGEGMEEGEFSE 370 380 390 400 410 420 430 440 pF1KB8 AREDLAALEKDYEEVGTDSFEEE-NEGEEF ::::::::::: ::::.:: : : .::: . CCDS21 AREDLAALEKDCEEVGVDSVEAEAEEGEAY 430 440 450 449 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 13:11:54 2016 done: Fri Nov 4 13:11:54 2016 Total Scan time: 2.760 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]