FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8467, 449 aa 1>>>pF1KB8467 449 - 449 aa - 449 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.6494+/-0.000411; mu= 21.0081+/- 0.026 mean_var=58.2429+/-11.545, 0's: 0 Z-trim(110.6): 67 B-trim: 311 in 1/50 Lambda= 0.168056 statistics sampled from 18949 (19023) to 18949 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.606), E-opt: 0.2 (0.223), width: 16 Scan time: 6.580 The best scores are: opt bits E(85289) NP_061816 (OMIM: 605742,613180) tubulin alpha-8 ch ( 449) 3014 739.4 4.5e-213 NP_005991 (OMIM: 191110,616208) tubulin alpha-4A c ( 448) 2782 683.1 3.9e-196 NP_005992 (OMIM: 602528) tubulin alpha-3C/D chain ( 450) 2781 682.9 4.6e-196 NP_006073 (OMIM: 602530) tubulin alpha-1B chain [H ( 451) 2774 681.2 1.5e-195 NP_001257328 (OMIM: 602529,611603) tubulin alpha-1 ( 451) 2772 680.7 2.1e-195 NP_006000 (OMIM: 602529,611603) tubulin alpha-1A c ( 451) 2772 680.7 2.1e-195 NP_001265481 (OMIM: 191110,616208) tubulin alpha-4 ( 433) 2679 658.2 1.2e-188 NP_001180343 (OMIM: 605742,613180) tubulin alpha-8 ( 383) 2553 627.6 1.8e-179 NP_001257329 (OMIM: 602529,611603) tubulin alpha-1 ( 416) 2541 624.7 1.4e-178 XP_016860313 (OMIM: 191110,616208) PREDICTED: tubu ( 295) 1905 470.4 2.8e-132 NP_821133 (OMIM: 156610,191130,615771) tubulin bet ( 444) 1262 314.6 3.3e-85 NP_006079 (OMIM: 602660) tubulin beta-4B chain [Ho ( 445) 1251 311.9 2.1e-84 NP_001060 (OMIM: 615101,615763) tubulin beta-2A ch ( 445) 1240 309.3 1.3e-83 NP_006077 (OMIM: 600638,602661,614039) tubulin bet ( 450) 1239 309.0 1.6e-83 NP_001276058 (OMIM: 602662) tubulin beta-4A chain ( 444) 1238 308.8 1.9e-83 NP_006078 (OMIM: 602662) tubulin beta-4A chain iso ( 444) 1238 308.8 1.9e-83 NP_821080 (OMIM: 610031,612850) tubulin beta-2B ch ( 445) 1238 308.8 1.9e-83 NP_001276056 (OMIM: 602662) tubulin beta-4A chain ( 489) 1238 308.8 2e-83 NP_001276052 (OMIM: 602662) tubulin beta-4A chain ( 495) 1238 308.8 2e-83 NP_001290453 (OMIM: 615103) tubulin beta-6 chain i ( 446) 1235 308.1 3.1e-83 NP_115914 (OMIM: 615103) tubulin beta-6 chain isof ( 446) 1235 308.1 3.1e-83 NP_817124 (OMIM: 616768,616780) tubulin beta-8 cha ( 444) 1220 304.4 3.9e-82 NP_001280141 (OMIM: 156610,191130,615771) tubulin ( 464) 1201 299.8 9.8e-81 NP_110400 (OMIM: 612901,613112) tubulin beta-1 cha ( 451) 1186 296.2 1.2e-79 NP_001280143 (OMIM: 156610,191130,615771) tubulin ( 400) 1139 284.8 2.9e-76 XP_016883574 (OMIM: 612901,613112) PREDICTED: tubu ( 429) 1103 276.1 1.3e-73 NP_001280145 (OMIM: 156610,191130,615771) tubulin ( 372) 1058 265.1 2.2e-70 NP_001280144 (OMIM: 156610,191130,615771) tubulin ( 372) 1058 265.1 2.2e-70 NP_001290456 (OMIM: 615103) tubulin beta-6 chain i ( 374) 1057 264.9 2.7e-70 NP_001184110 (OMIM: 600638,602661,614039) tubulin ( 378) 1053 263.9 5.3e-70 NP_001276060 (OMIM: 602662) tubulin beta-4A chain ( 372) 1045 261.9 2e-69 NP_001276059 (OMIM: 602662) tubulin beta-4A chain ( 372) 1045 261.9 2e-69 XP_011517761 (OMIM: 616768,616780) PREDICTED: tubu ( 372) 1034 259.3 1.3e-68 NP_001290457 (OMIM: 615103) tubulin beta-6 chain i ( 381) 997 250.3 6.5e-66 NP_001297244 (OMIM: 615101,615763) tubulin beta-2A ( 360) 989 248.4 2.4e-65 NP_001290455 (OMIM: 615103) tubulin beta-6 chain i ( 409) 984 247.2 6.1e-65 XP_016871681 (OMIM: 616768,616780) PREDICTED: tubu ( 332) 900 226.8 7e-59 XP_016871682 (OMIM: 616768,616780) PREDICTED: tubu ( 332) 900 226.8 7e-59 NP_001061 (OMIM: 191135,615412) tubulin gamma-1 ch ( 451) 799 202.4 2.1e-51 NP_057521 (OMIM: 605785) tubulin gamma-2 chain iso ( 451) 792 200.7 6.8e-51 NP_001290458 (OMIM: 615103) tubulin beta-6 chain i ( 300) 779 197.4 4.4e-50 NP_001290459 (OMIM: 615103) tubulin beta-6 chain i ( 300) 779 197.4 4.4e-50 XP_011517762 (OMIM: 616768,616780) PREDICTED: tubu ( 291) 726 184.5 3.2e-46 NP_001307438 (OMIM: 605785) tubulin gamma-2 chain ( 460) 534 138.1 4.7e-32 NP_057346 (OMIM: 607345) tubulin epsilon chain [Ho ( 475) 456 119.2 2.4e-26 XP_011522916 (OMIM: 605785) PREDICTED: tubulin gam ( 298) 433 113.5 7.8e-25 XP_016879942 (OMIM: 605785) PREDICTED: tubulin gam ( 298) 433 113.5 7.8e-25 XP_016879944 (OMIM: 605785) PREDICTED: tubulin gam ( 274) 410 107.9 3.5e-23 XP_016879946 (OMIM: 605785) PREDICTED: tubulin gam ( 274) 410 107.9 3.5e-23 XP_016879943 (OMIM: 605785) PREDICTED: tubulin gam ( 274) 410 107.9 3.5e-23 >>NP_061816 (OMIM: 605742,613180) tubulin alpha-8 chain (449 aa) initn: 3014 init1: 3014 opt: 3014 Z-score: 3946.3 bits: 739.4 E(85289): 4.5e-213 Smith-Waterman score: 3014; 100.0% identity (100.0% similar) in 449 aa overlap (1-449:1-449) 10 20 30 40 50 60 pF1KB8 MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 HVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 RIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 QMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_061 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 370 380 390 400 410 420 430 440 pF1KB8 AREDLAALEKDYEEVGTDSFEEENEGEEF ::::::::::::::::::::::::::::: NP_061 AREDLAALEKDYEEVGTDSFEEENEGEEF 430 440 >>NP_005991 (OMIM: 191110,616208) tubulin alpha-4A chain (448 aa) initn: 2782 init1: 2782 opt: 2782 Z-score: 3642.3 bits: 683.1 E(85289): 3.9e-196 Smith-Waterman score: 2782; 90.0% identity (96.4% similar) in 448 aa overlap (1-448:1-448) 10 20 30 40 50 60 pF1KB8 MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGK :::::::::::::::.:::::::.::::::: :: . .. . . :::::::: ::: :: NP_005 MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLD ::::::..::::::.::.: : :::::::::::::::::::::::::::.::: :: ::: NP_005 HVPRAVFVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTA :::::.: :.::::::.:::::::::::::::::::::.::::::::::.:::::::::: NP_005 RIRKLSDQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNS :::::::::::::::::::::::::::::.::::.:::::::::::::::::..:::: . NP_005 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPP ::::::::::::::::.::::::::::::.:::::::::.:::::::::::::::::::: NP_005 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 370 380 390 400 410 420 430 440 pF1KB8 AREDLAALEKDYEEVGTDSFEEENEGEEF ::::.::::::::::: ::.:.:.:::: NP_005 AREDMAALEKDYEEVGIDSYEDEDEGEE 430 440 >>NP_005992 (OMIM: 602528) tubulin alpha-3C/D chain [Hom (450 aa) initn: 2768 init1: 2768 opt: 2781 Z-score: 3641.0 bits: 682.9 E(85289): 4.6e-196 Smith-Waterman score: 2781; 90.7% identity (96.9% similar) in 450 aa overlap (1-449:1-450) 10 20 30 40 50 60 pF1KB8 MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGK ::::::.::::::::::::::::.::::::: :: . .. . . ::::.::::::: :: NP_005 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLD ::::::..:::::::::::.:::::::::::::::::::::::::::::.::: .::::: NP_005 HVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTA :::::.: :.:::::::::::::::::::.::::::::.::::::::::::::::::::: NP_005 RIRKLADLCTGLQGFLIFHSFGGGTGSGFASLLMERLSVDYGKKSKLEFAIYPAPQVSTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: NP_005 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNS :::::::::::::::::::::::::::::.::::.:::::::::::::::::..:::: . NP_005 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPP :::::::::::::::::::::::::::::.:::.:::::::::::::::::::::::::: NP_005 QMVKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 370 380 390 400 410 420 430 440 pF1KB8 AREDLAALEKDYEEVGTDSFEEE-NEGEEF ::::::::::::::::.:: : : .::::. NP_005 AREDLAALEKDYEEVGVDSVEAEAEEGEEY 430 440 450 >>NP_006073 (OMIM: 602530) tubulin alpha-1B chain [Homo (451 aa) initn: 2767 init1: 2767 opt: 2774 Z-score: 3631.8 bits: 681.2 E(85289): 1.5e-195 Smith-Waterman score: 2774; 89.8% identity (96.7% similar) in 451 aa overlap (1-449:1-451) 10 20 30 40 50 60 pF1KB8 MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGK ::::::.::::::::::::::::.::::::: :: . .. . . ::::.::::::: :: NP_006 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLD ::::::..::::::.::::.:::::::::::::::::::::::::::::.::: :::::: NP_006 HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTA :::::.: :.::::::.:::::::::::::::::::::.::::::::::.:::::::::: NP_006 RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNS :::::::::::::::::::::::::::::.::::.:::::::::::::::::..:::: . NP_006 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPP ::::::::::::::::.::::::::::::.:::.:::::.:::::::::::::::::::: NP_006 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 370 380 390 400 410 420 430 440 pF1KB8 AREDLAALEKDYEEVGTDSFEEENE--GEEF ::::.:::::::::::.:: : :.: :::. NP_006 AREDMAALEKDYEEVGVDSVEGEGEEEGEEY 430 440 450 >>NP_001257328 (OMIM: 602529,611603) tubulin alpha-1A ch (451 aa) initn: 2765 init1: 2765 opt: 2772 Z-score: 3629.2 bits: 680.7 E(85289): 2.1e-195 Smith-Waterman score: 2772; 89.8% identity (96.7% similar) in 451 aa overlap (1-449:1-451) 10 20 30 40 50 60 pF1KB8 MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGK ::::::.::::::::::::::::.::::::: :: . .. . . ::::.::::::: :: NP_001 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLD ::::::..::::::.::::.:::::::::::::::::::::::::::::.::: :::::: NP_001 HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTA :::::.: :.::::::.:::::::::::::::::::::.::::::::::.:::::::::: NP_001 RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: NP_001 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNS :::::::::::::::::::::::::::::.::::.:::::::::::::::::..:::: . NP_001 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPP ::::::::::::::::.::::::::::::.:::.:::::::::::::::::::::::::: NP_001 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 370 380 390 400 410 420 430 440 pF1KB8 AREDLAALEKDYEEVGTDSFEEENE--GEEF ::::.:::::::::::.:: : :.: :::. NP_001 AREDMAALEKDYEEVGVDSVEGEGEEEGEEY 430 440 450 >>NP_006000 (OMIM: 602529,611603) tubulin alpha-1A chain (451 aa) initn: 2765 init1: 2765 opt: 2772 Z-score: 3629.2 bits: 680.7 E(85289): 2.1e-195 Smith-Waterman score: 2772; 89.8% identity (96.7% similar) in 451 aa overlap (1-449:1-451) 10 20 30 40 50 60 pF1KB8 MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGK ::::::.::::::::::::::::.::::::: :: . .. . . ::::.::::::: :: NP_006 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 HVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLD ::::::..::::::.::::.:::::::::::::::::::::::::::::.::: :::::: NP_006 HVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTA :::::.: :.::::::.:::::::::::::::::::::.::::::::::.:::::::::: NP_006 RIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA :::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::: NP_006 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNS :::::::::::::::::::::::::::::.::::.:::::::::::::::::..:::: . NP_006 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 QMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPP ::::::::::::::::.::::::::::::.:::.:::::::::::::::::::::::::: NP_006 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPP 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 370 380 390 400 410 420 430 440 pF1KB8 AREDLAALEKDYEEVGTDSFEEENE--GEEF ::::.:::::::::::.:: : :.: :::. NP_006 AREDMAALEKDYEEVGVDSVEGEGEEEGEEY 430 440 450 >>NP_001265481 (OMIM: 191110,616208) tubulin alpha-4A ch (433 aa) initn: 2679 init1: 2679 opt: 2679 Z-score: 3507.5 bits: 658.2 E(85289): 1.2e-188 Smith-Waterman score: 2679; 89.6% identity (96.3% similar) in 433 aa overlap (16-448:1-433) 10 20 30 40 50 60 pF1KB8 MRECISVHVGQAGVQIGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGK .:::::::.::::::: :: . .. . . :::::::: ::: :: NP_001 MGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFCETGAGK 10 20 30 40 70 80 90 100 110 120 pF1KB8 HVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLD ::::::..::::::.::.: : :::::::::::::::::::::::::::.::: :: ::: NP_001 HVPRAVFVDLEPTVIDEIRNGPYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLD 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 RIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTA :::::.: :.::::::.:::::::::::::::::::::.::::::::::.:::::::::: NP_001 RIRKLSDQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTA 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB8 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITA 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB8 SLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNS :::::::::::::::::::::::::::::.::::.:::::::::::::::::..:::: . NP_001 SLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPAN 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB8 QMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPP ::::::::::::::::.::::::::::::.:::::::::.:::::::::::::::::::: NP_001 QMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPP 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB8 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE 350 360 370 380 390 400 430 440 pF1KB8 AREDLAALEKDYEEVGTDSFEEENEGEEF ::::.::::::::::: ::.:.:.:::: NP_001 AREDMAALEKDYEEVGIDSYEDEDEGEE 410 420 430 >>NP_001180343 (OMIM: 605742,613180) tubulin alpha-8 cha (383 aa) initn: 2553 init1: 2553 opt: 2553 Z-score: 3343.2 bits: 627.6 E(85289): 1.8e-179 Smith-Waterman score: 2553; 100.0% identity (100.0% similar) in 383 aa overlap (67-449:1-383) 40 50 60 70 80 90 pF1KB8 DAQASKINDDDSFTTFFSETGNGKHVPRAVMIDLEPTVVDEVRAGTYRQLFHPEQLITGK :::::::::::::::::::::::::::::: NP_001 MIDLEPTVVDEVRAGTYRQLFHPEQLITGK 10 20 30 100 110 120 130 140 150 pF1KB8 EDAANNYARGHYTVGKESIDLVLDRIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDAANNYARGHYTVGKESIDLVLDRIRKLTDACSGLQGFLIFHSFGGGTGSGFTSLLMER 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB8 LSLDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSLDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRN 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB8 LDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLVTYAPII 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB8 SAEKAYHEQLSVAEITSSCFEPNSQMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SAEKAYHEQLSVAEITSSCFEPNSQMVKCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIK 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB8 TKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFD 280 290 300 310 320 330 400 410 420 430 440 pF1KB8 LMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGTDSFEEENEGEEF ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGTDSFEEENEGEEF 340 350 360 370 380 >>NP_001257329 (OMIM: 602529,611603) tubulin alpha-1A ch (416 aa) initn: 2534 init1: 2534 opt: 2541 Z-score: 3327.0 bits: 624.7 E(85289): 1.4e-178 Smith-Waterman score: 2541; 92.1% identity (98.0% similar) in 406 aa overlap (46-449:11-416) 20 30 40 50 60 70 pF1KB8 IGNACWELFCLEHGIQADGTFDAQASKINDDDSFTTFFSETGNGKHVPRAVMIDLEPTVV ::::.::::::: ::::::::..::::::. NP_001 MPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVI 10 20 30 40 80 90 100 110 120 130 pF1KB8 DEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTVGKESIDLVLDRIRKLTDACSGLQGF ::::.:::::::::::::::::::::::::::::.::: :::::::::::.: :.::::: NP_001 DEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGF 50 60 70 80 90 100 140 150 160 170 180 190 pF1KB8 LIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTL :.:::::::::::::::::::::.::::::::::.::::::::::::::::::::::::: NP_001 LVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTL 110 120 130 140 150 160 200 210 220 230 240 250 pF1KB8 EHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEF ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: NP_001 EHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEF 170 180 190 200 210 220 260 270 280 290 300 310 pF1KB8 QTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNSQMVKCDPRHGKYMAC ::::::::::::::.::::.:::::::::::::::::..:::: .::::::::::::::: NP_001 QTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMAC 230 240 250 260 270 280 320 330 340 350 360 370 pF1KB8 CMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAV :.::::::::::::.:::.::::::::::::::::::::::::::::::::::::::::: NP_001 CLLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAV 290 300 310 320 330 340 380 390 400 410 420 430 pF1KB8 CMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEV :::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::: NP_001 CMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEV 350 360 370 380 390 400 440 pF1KB8 GTDSFEEENE--GEEF :.:: : :.: :::. NP_001 GVDSVEGEGEEEGEEY 410 >>XP_016860313 (OMIM: 191110,616208) PREDICTED: tubulin (295 aa) initn: 1905 init1: 1905 opt: 1905 Z-score: 2495.7 bits: 470.4 E(85289): 2.8e-132 Smith-Waterman score: 1905; 94.6% identity (99.3% similar) in 295 aa overlap (154-448:1-295) 130 140 150 160 170 180 pF1KB8 KLTDACSGLQGFLIFHSFGGGTGSGFTSLLMERLSLDYGKKSKLEFAIYPAPQVSTAVVE :::::.::::::::::.::::::::::::: XP_016 MERLSVDYGKKSKLEFSIYPAPQVSTAVVE 10 20 30 190 200 210 220 230 240 pF1KB8 PYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLR 40 50 60 70 80 90 250 260 270 280 290 300 pF1KB8 FDGALNVDLTEFQTNLVPYPRIHFPLVTYAPIISAEKAYHEQLSVAEITSSCFEPNSQMV ::::::::::::::::::::::::::.::::.:::::::::::::::::..:::: .::: XP_016 FDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMV 100 110 120 130 140 150 310 320 330 340 350 360 pF1KB8 KCDPRHGKYMACCMLYRGDVVPKDVNVAIAAIKTKRTIQFVDWCPTGFKVGINYQPPTVV :::::::::::::.::::::::::::.:::::::::.::::::::::::::::::::::: XP_016 KCDPRHGKYMACCLLYRGDVVPKDVNAAIAAIKTKRSIQFVDWCPTGFKVGINYQPPTVV 160 170 180 190 200 210 370 380 390 400 410 420 pF1KB8 PGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEARE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEARE 220 230 240 250 260 270 430 440 pF1KB8 DLAALEKDYEEVGTDSFEEENEGEEF :.::::::::::: ::.:.:.:::: XP_016 DMAALEKDYEEVGIDSYEDEDEGEE 280 290 449 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 13:11:55 2016 done: Fri Nov 4 13:11:56 2016 Total Scan time: 6.580 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]