Result of FASTA (omim) for pF1KB8468
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8468, 297 aa
  1>>>pF1KB8468 297 - 297 aa - 297 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 12.4825+/-0.000742; mu= -21.8755+/- 0.043
 mean_var=716.6701+/-158.180, 0's: 0 Z-trim(112.9): 1780  B-trim: 0 in 0/56
 Lambda= 0.047909
 statistics sampled from 19611 (22054) to 19611 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.624), E-opt: 0.2 (0.259), width:  16
 Scan time:  7.380

The best scores are:                                      opt bits E(85289)
XP_005270360 (OMIM: 116940) PREDICTED: cyclin-depe ( 297) 1956 151.0 2.6e-36
NP_001307847 (OMIM: 116940) cyclin-dependent kinas ( 297) 1956 151.0 2.6e-36
NP_001777 (OMIM: 116940) cyclin-dependent kinase 1 ( 297) 1956 151.0 2.6e-36
NP_001789 (OMIM: 116953) cyclin-dependent kinase 2 ( 298) 1327 107.5 3.2e-23
NP_001249 (OMIM: 123828) cyclin-dependent kinase 3 ( 305) 1322 107.2 4.1e-23
NP_004926 (OMIM: 123831,616342) cyclin-dependent-l ( 292) 1099 91.8 1.8e-18
NP_001163935 (OMIM: 603440) cyclin-dependent kinas ( 523) 1101 92.2 2.3e-18
NP_002586 (OMIM: 603440) cyclin-dependent kinase 1 ( 523) 1101 92.2 2.3e-18
XP_016874894 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 1101 92.2 2.3e-18
XP_016874895 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 1101 92.2 2.3e-18
XP_016885061 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 1058 89.2 1.7e-17
XP_016885060 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 1058 89.2 1.7e-17
NP_006192 (OMIM: 311550) cyclin-dependent kinase 1 ( 496) 1058 89.2 1.7e-17
XP_016885062 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 1058 89.2 1.7e-17
XP_016885059 (OMIM: 311550) PREDICTED: cyclin-depe ( 496) 1058 89.2 1.7e-17
XP_011542226 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1058 89.2 1.7e-17
XP_011542228 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1058 89.2 1.7e-17
XP_011542229 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1058 89.2 1.7e-17
XP_011542230 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1058 89.2 1.7e-17
XP_011542227 (OMIM: 311550) PREDICTED: cyclin-depe ( 497) 1058 89.2 1.7e-17
NP_148978 (OMIM: 311550) cyclin-dependent kinase 1 ( 502) 1058 89.2 1.7e-17
XP_011542225 (OMIM: 311550) PREDICTED: cyclin-depe ( 503) 1058 89.2 1.7e-17
XP_011542224 (OMIM: 311550) PREDICTED: cyclin-depe ( 540) 1058 89.3 1.8e-17
XP_016885058 (OMIM: 311550) PREDICTED: cyclin-depe ( 543) 1058 89.3 1.8e-17
XP_011542223 (OMIM: 311550) PREDICTED: cyclin-depe ( 544) 1058 89.3 1.8e-17
NP_001163931 (OMIM: 311550) cyclin-dependent kinas ( 570) 1058 89.3 1.9e-17
XP_011542222 (OMIM: 311550) PREDICTED: cyclin-depe ( 571) 1058 89.3 1.9e-17
NP_002587 (OMIM: 169190) cyclin-dependent kinase 1 ( 474) 1050 88.7 2.5e-17
NP_997667 (OMIM: 169190) cyclin-dependent kinase 1 ( 474) 1050 88.7 2.5e-17
NP_997668 (OMIM: 169190) cyclin-dependent kinase 1 ( 504) 1050 88.7 2.6e-17
XP_011507904 (OMIM: 169190) PREDICTED: cyclin-depe ( 542) 1050 88.7 2.7e-17
XP_016856912 (OMIM: 169190) PREDICTED: cyclin-depe ( 572) 1050 88.8 2.8e-17
XP_011536034 (OMIM: 116953) PREDICTED: cyclin-depe ( 346)  939 80.8 4.2e-15
XP_005250496 (OMIM: 610679) PREDICTED: cyclin-depe ( 423)  920 79.6 1.2e-14
XP_016867809 (OMIM: 610679) PREDICTED: cyclin-depe ( 423)  920 79.6 1.2e-14
XP_005250495 (OMIM: 610679) PREDICTED: cyclin-depe ( 423)  920 79.6 1.2e-14
XP_016867810 (OMIM: 610679) PREDICTED: cyclin-depe ( 423)  920 79.6 1.2e-14
XP_016867811 (OMIM: 610679) PREDICTED: cyclin-depe ( 423)  920 79.6 1.2e-14
NP_001274065 (OMIM: 610679) cyclin-dependent kinas ( 423)  920 79.6 1.2e-14
XP_005250493 (OMIM: 610679) PREDICTED: cyclin-depe ( 450)  920 79.6 1.2e-14
NP_036527 (OMIM: 610679) cyclin-dependent kinase 1 ( 451)  920 79.6 1.2e-14
XP_011514608 (OMIM: 610679) PREDICTED: cyclin-depe ( 469)  920 79.7 1.2e-14
NP_001274064 (OMIM: 610679) cyclin-dependent kinas ( 469)  920 79.7 1.2e-14
NP_203698 (OMIM: 116940) cyclin-dependent kinase 1 ( 240)  902 78.0   2e-14
NP_001250 (OMIM: 603368,616080) cyclin-dependent k ( 326)  885 77.0 5.3e-14
NP_001138778 (OMIM: 603368,616080) cyclin-dependen ( 326)  885 77.0 5.3e-14
XP_006715898 (OMIM: 603368,616080) PREDICTED: cycl ( 326)  885 77.0 5.3e-14
NP_001790 (OMIM: 601955) cyclin-dependent kinase 7 ( 346)  852 74.8 2.7e-13
NP_631897 (OMIM: 616147) cyclin-dependent kinase 1 ( 384)  839 74.0 5.3e-13
XP_005246839 (OMIM: 616147) PREDICTED: cyclin-depe ( 384)  839 74.0 5.3e-13


>>XP_005270360 (OMIM: 116940) PREDICTED: cyclin-dependen  (297 aa)
 initn: 1956 init1: 1956 opt: 1956  Z-score: 772.8  bits: 151.0 E(85289): 2.6e-36
Smith-Waterman score: 1956; 99.7% identity (99.7% similar) in 297 aa overlap (1-297:1-297)

               10        20        30        40        50        60
pF1KB8 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT
              190       200       210       220       230       240

              250       260       270       280       290       
pF1KB8 FPKWKPGSLASHVKNLDENGLDLLSKMLTYDPAKRISGKMALNHPYFNDLDNQIKKM
       :::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
XP_005 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM
              250       260       270       280       290       

>>NP_001307847 (OMIM: 116940) cyclin-dependent kinase 1   (297 aa)
 initn: 1956 init1: 1956 opt: 1956  Z-score: 772.8  bits: 151.0 E(85289): 2.6e-36
Smith-Waterman score: 1956; 99.7% identity (99.7% similar) in 297 aa overlap (1-297:1-297)

               10        20        30        40        50        60
pF1KB8 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT
              190       200       210       220       230       240

              250       260       270       280       290       
pF1KB8 FPKWKPGSLASHVKNLDENGLDLLSKMLTYDPAKRISGKMALNHPYFNDLDNQIKKM
       :::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
NP_001 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM
              250       260       270       280       290       

>>NP_001777 (OMIM: 116940) cyclin-dependent kinase 1 iso  (297 aa)
 initn: 1956 init1: 1956 opt: 1956  Z-score: 772.8  bits: 151.0 E(85289): 2.6e-36
Smith-Waterman score: 1956; 99.7% identity (99.7% similar) in 297 aa overlap (1-297:1-297)

               10        20        30        40        50        60
pF1KB8 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT
              190       200       210       220       230       240

              250       260       270       280       290       
pF1KB8 FPKWKPGSLASHVKNLDENGLDLLSKMLTYDPAKRISGKMALNHPYFNDLDNQIKKM
       :::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
NP_001 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM
              250       260       270       280       290       

>>NP_001789 (OMIM: 116953) cyclin-dependent kinase 2 iso  (298 aa)
 initn: 1327 init1: 899 opt: 1327  Z-score: 537.8  bits: 107.5 E(85289): 3.2e-23
Smith-Waterman score: 1327; 65.8% identity (85.2% similar) in 298 aa overlap (1-297:1-296)

               10        20        30        40        50        60
pF1KB8 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
       ::.. :.:::::::::::::.:.: ::.:::.:::::..: ::::::::::::::::: :
NP_001 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
               10        20        30        40        50        60

               70        80        90        100       110         
pF1KB8 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLD-SIPPGQYMDSSLVKSYLYQILQGIVFC
       ::::.: ::.  ...:::.:::: .::::..: :   :  .   :.::::.:.:::..::
NP_001 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFC
               70        80        90         100       110        

     120       130       140       150       160       170         
pF1KB8 HSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSA
       ::.::::::::::::::. .:.:::::::::::::.:.:.:::::::::::.::.:::  
NP_001 HSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCK
      120       130       140       150       160       170        

     180       190       200       210       220       230         
pF1KB8 RYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN
        ::: :::::.: ::::..:.. :: :::::::::::::.::::.. ::: : :. ::: 
NP_001 YYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP
      180       190       200       210       220       230        

     240       250       260       270       280       290         
pF1KB8 TFPKWKPGSLASHVKNLDENGLDLLSKMLTYDPAKRISGKMALNHPYFNDLDNQIKKM  
       .::::   .... :  :::.: .:::.:: ::: ::::.: :: ::.:.:. . . ..  
NP_001 SFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
      240       250       260       270       280       290        

>>NP_001249 (OMIM: 123828) cyclin-dependent kinase 3 [Ho  (305 aa)
 initn: 1312 init1: 900 opt: 1322  Z-score: 535.9  bits: 107.2 E(85289): 4.1e-23
Smith-Waterman score: 1322; 67.0% identity (86.1% similar) in 288 aa overlap (1-288:1-287)

               10        20        30        40        50        60
pF1KB8 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
       :. . :.:::::::::::::.... :::.::.:::::. : :::::::::::::::::.:
NP_001 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH
       :::: : ::. .. .:::.:::::.:::::.:: : :. .   :.::::.:.:::. :::
NP_001 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTP-GSELPLHLIKSYLFQLLQGVSFCH
               70        80        90        100       110         

              130       140       150       160       170       180
pF1KB8 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR
       :.::.:::::::::::.. :.:::::::::::::.:.:.:::::::::::.::.::::  
NP_001 SHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKF
     120       130       140       150       160       170         

              190       200       210       220       230       240
pF1KB8 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT
       :.: ::::::: ::::..:.: :: ::::::::::::: ::::....:: : .: :::..
NP_001 YTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGS
     180       190       200       210       220       230         

              250       260       270       280       290          
pF1KB8 FPKWKPGSLASHVKNLDENGLDLLSKMLTYDPAKRISGKMALNHPYFNDLDNQIKKM   
       ::::   .:   : ::. .: ::: ..: :::..::..: :: ::::.            
NP_001 FPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEPSPAARQYV
     240       250       260       270       280       290         

NP_001 LQRFRH
     300     

>>NP_004926 (OMIM: 123831,616342) cyclin-dependent-like   (292 aa)
 initn: 1095 init1: 483 opt: 1099  Z-score: 452.8  bits: 91.8 E(85289): 1.8e-18
Smith-Waterman score: 1099; 57.3% identity (82.3% similar) in 293 aa overlap (1-290:1-289)

               10        20        30        40        50        60
pF1KB8 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
       :. : :.:::::::::.:.:.... : ..::.:..::....:::::.:.::: :::::.:
NP_004 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH
        ::: :.::: .:..: :.::: ..:::::.::   :. .:  .:::.:.:.:.:. :::
NP_004 KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCN-GD-LDPEIVKSFLFQLLKGLGFCH
               70        80        90         100       110        

              130       140       150       160       170       180
pF1KB8 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR
       :: :::::::::::::. .: .::::::::::::::.: :. :::::::: :.::.:.  
NP_004 SRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKL
      120       130       140       150       160       170        

              190       200        210       220       230         
pF1KB8 YSTPVDIWSIGTIFAELATK-KPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN
       ::: .:.:: : ::::::.  .::: :..  ::: :::: ::::..: :: . .: ::: 
NP_004 YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYK-
      180       190       200       210       220       230        

     240         250       260       270       280       290       
pF1KB8 TFPKWKPG--SLASHVKNLDENGLDLLSKMLTYDPAKRISGKMALNHPYFNDLDNQIKKM
        .: . :.  ::.. : .:. .: :::...:  .:..:::.. ::.::::.:.       
NP_004 PYPMY-PATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP    
       240        250       260       270       280       290      

>>NP_001163935 (OMIM: 603440) cyclin-dependent kinase 17  (523 aa)
 initn: 1103 init1: 593 opt: 1101  Z-score: 450.8  bits: 92.2 E(85289): 2.3e-18
Smith-Waterman score: 1101; 54.4% identity (81.5% similar) in 298 aa overlap (1-297:189-483)

                                             10        20        30
pF1KB8                               MEDYTKIEKIGEGTYGVVYKGRHKTTGQVV
                                     :: : :.::.:::::..::::: : : ..:
NP_001 EKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLV
      160       170       180       190       200       210        

               40        50        60        70        80        90
pF1KB8 AMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKY
       :.:.:::: .:::.: :::::.::::.:.: :::.:.:..  :. : :.::.:. :::.:
NP_001 ALKEIRLE-HEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQY
      220        230       240       250       260       270       

              100       110       120       130       140       150
pF1KB8 LDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLA
       .:.   :. :.   :: .:::::.:...:: :.:::::::::::::..:: .::::::::
NP_001 MDDC--GNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLA
       280         290       300       310       320       330     

              160       170       180       190       200       210
pF1KB8 RAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEI
       :: ..: ..:..:::::::: :.:::::..::: .:.:..: :: :.:. .::: :..  
NP_001 RAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVE
         340       350       360       370       380       390     

              220       230        240       250       260         
pF1KB8 DQLFRIFRALGTPNNEVWPEVESLQDYKN-TFPKWKPGSLASHVKNLDENGLDLLSKMLT
       :.:  ::: ::::..:.:: . : ...:: .:::.::  : .:.  :: .:..:..:.: 
NP_001 DELHLIFRLLGTPSQETWPGISSNEEFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQ
         400       410       420       430       440       450     

     270       280       290                                       
pF1KB8 YDPAKRISGKMALNHPYFNDLDNQIKKM                                
       :.  ::.:.. :..: :: .:  .:. .                                
NP_001 YESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGVFV
         460       470       480       490       500       510     

>>NP_002586 (OMIM: 603440) cyclin-dependent kinase 17 is  (523 aa)
 initn: 1103 init1: 593 opt: 1101  Z-score: 450.8  bits: 92.2 E(85289): 2.3e-18
Smith-Waterman score: 1101; 54.4% identity (81.5% similar) in 298 aa overlap (1-297:189-483)

                                             10        20        30
pF1KB8                               MEDYTKIEKIGEGTYGVVYKGRHKTTGQVV
                                     :: : :.::.:::::..::::: : : ..:
NP_002 EKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLV
      160       170       180       190       200       210        

               40        50        60        70        80        90
pF1KB8 AMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKY
       :.:.:::: .:::.: :::::.::::.:.: :::.:.:..  :. : :.::.:. :::.:
NP_002 ALKEIRLE-HEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQY
      220        230       240       250       260       270       

              100       110       120       130       140       150
pF1KB8 LDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLA
       .:.   :. :.   :: .:::::.:...:: :.:::::::::::::..:: .::::::::
NP_002 MDDC--GNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLA
       280         290       300       310       320       330     

              160       170       180       190       200       210
pF1KB8 RAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEI
       :: ..: ..:..:::::::: :.:::::..::: .:.:..: :: :.:. .::: :..  
NP_002 RAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVE
         340       350       360       370       380       390     

              220       230        240       250       260         
pF1KB8 DQLFRIFRALGTPNNEVWPEVESLQDYKN-TFPKWKPGSLASHVKNLDENGLDLLSKMLT
       :.:  ::: ::::..:.:: . : ...:: .:::.::  : .:.  :: .:..:..:.: 
NP_002 DELHLIFRLLGTPSQETWPGISSNEEFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQ
         400       410       420       430       440       450     

     270       280       290                                       
pF1KB8 YDPAKRISGKMALNHPYFNDLDNQIKKM                                
       :.  ::.:.. :..: :: .:  .:. .                                
NP_002 YESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGHGK
         460       470       480       490       500       510     

>>XP_016874894 (OMIM: 603440) PREDICTED: cyclin-dependen  (523 aa)
 initn: 1103 init1: 593 opt: 1101  Z-score: 450.8  bits: 92.2 E(85289): 2.3e-18
Smith-Waterman score: 1101; 54.4% identity (81.5% similar) in 298 aa overlap (1-297:189-483)

                                             10        20        30
pF1KB8                               MEDYTKIEKIGEGTYGVVYKGRHKTTGQVV
                                     :: : :.::.:::::..::::: : : ..:
XP_016 EKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLV
      160       170       180       190       200       210        

               40        50        60        70        80        90
pF1KB8 AMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKY
       :.:.:::: .:::.: :::::.::::.:.: :::.:.:..  :. : :.::.:. :::.:
XP_016 ALKEIRLE-HEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQY
      220        230       240       250       260       270       

              100       110       120       130       140       150
pF1KB8 LDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLA
       .:.   :. :.   :: .:::::.:...:: :.:::::::::::::..:: .::::::::
XP_016 MDDC--GNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLA
       280         290       300       310       320       330     

              160       170       180       190       200       210
pF1KB8 RAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEI
       :: ..: ..:..:::::::: :.:::::..::: .:.:..: :: :.:. .::: :..  
XP_016 RAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVE
         340       350       360       370       380       390     

              220       230        240       250       260         
pF1KB8 DQLFRIFRALGTPNNEVWPEVESLQDYKN-TFPKWKPGSLASHVKNLDENGLDLLSKMLT
       :.:  ::: ::::..:.:: . : ...:: .:::.::  : .:.  :: .:..:..:.: 
XP_016 DELHLIFRLLGTPSQETWPGISSNEEFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQ
         400       410       420       430       440       450     

     270       280       290                                       
pF1KB8 YDPAKRISGKMALNHPYFNDLDNQIKKM                                
       :.  ::.:.. :..: :: .:  .:. .                                
XP_016 YESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGHGK
         460       470       480       490       500       510     

>>XP_016874895 (OMIM: 603440) PREDICTED: cyclin-dependen  (523 aa)
 initn: 1103 init1: 593 opt: 1101  Z-score: 450.8  bits: 92.2 E(85289): 2.3e-18
Smith-Waterman score: 1101; 54.4% identity (81.5% similar) in 298 aa overlap (1-297:189-483)

                                             10        20        30
pF1KB8                               MEDYTKIEKIGEGTYGVVYKGRHKTTGQVV
                                     :: : :.::.:::::..::::: : : ..:
XP_016 EKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLV
      160       170       180       190       200       210        

               40        50        60        70        80        90
pF1KB8 AMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKY
       :.:.:::: .:::.: :::::.::::.:.: :::.:.:..  :. : :.::.:. :::.:
XP_016 ALKEIRLE-HEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQY
      220        230       240       250       260       270       

              100       110       120       130       140       150
pF1KB8 LDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLA
       .:.   :. :.   :: .:::::.:...:: :.:::::::::::::..:: .::::::::
XP_016 MDDC--GNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLA
       280         290       300       310       320       330     

              160       170       180       190       200       210
pF1KB8 RAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEI
       :: ..: ..:..:::::::: :.:::::..::: .:.:..: :: :.:. .::: :..  
XP_016 RAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVE
         340       350       360       370       380       390     

              220       230        240       250       260         
pF1KB8 DQLFRIFRALGTPNNEVWPEVESLQDYKN-TFPKWKPGSLASHVKNLDENGLDLLSKMLT
       :.:  ::: ::::..:.:: . : ...:: .:::.::  : .:.  :: .:..:..:.: 
XP_016 DELHLIFRLLGTPSQETWPGISSNEEFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQ
         400       410       420       430       440       450     

     270       280       290                                       
pF1KB8 YDPAKRISGKMALNHPYFNDLDNQIKKM                                
       :.  ::.:.. :..: :: .:  .:. .                                
XP_016 YESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGHGK
         460       470       480       490       500       510     




297 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 23:18:54 2016 done: Sat Nov  5 23:18:55 2016
 Total Scan time:  7.380 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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