FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8470, 822 aa 1>>>pF1KB8470 822 - 822 aa - 822 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 18.8809+/-0.000804; mu= -48.5847+/- 0.047 mean_var=1063.6006+/-241.770, 0's: 0 Z-trim(113.0): 691 B-trim: 417 in 1/57 Lambda= 0.039326 statistics sampled from 21419 (22107) to 21419 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.599), E-opt: 0.2 (0.259), width: 16 Scan time: 12.540 The best scores are: opt bits E(85289) NP_001018074 (OMIM: 600456,613886) BDNF/NT-3 growt ( 822) 5638 337.6 1.4e-91 XP_016870243 (OMIM: 600456,613886) PREDICTED: BDNF ( 822) 5638 337.6 1.4e-91 XP_016870242 (OMIM: 600456,613886) PREDICTED: BDNF ( 822) 5638 337.6 1.4e-91 XP_016870241 (OMIM: 600456,613886) PREDICTED: BDNF ( 822) 5638 337.6 1.4e-91 XP_011517020 (OMIM: 600456,613886) PREDICTED: BDNF ( 822) 5638 337.6 1.4e-91 NP_001018076 (OMIM: 600456,613886) BDNF/NT-3 growt ( 537) 3621 223.0 2.8e-57 XP_016870246 (OMIM: 600456,613886) PREDICTED: BDNF ( 537) 3621 223.0 2.8e-57 XP_011517022 (OMIM: 600456,613886) PREDICTED: BDNF ( 537) 3621 223.0 2.8e-57 XP_016870247 (OMIM: 600456,613886) PREDICTED: BDNF ( 477) 3209 199.6 2.8e-50 XP_016870250 (OMIM: 600456,613886) PREDICTED: BDNF ( 477) 3209 199.6 2.8e-50 XP_016870248 (OMIM: 600456,613886) PREDICTED: BDNF ( 477) 3209 199.6 2.8e-50 XP_016870249 (OMIM: 600456,613886) PREDICTED: BDNF ( 477) 3209 199.6 2.8e-50 NP_001007098 (OMIM: 600456,613886) BDNF/NT-3 growt ( 477) 3209 199.6 2.8e-50 XP_005252064 (OMIM: 600456,613886) PREDICTED: BDNF ( 477) 3209 199.6 2.8e-50 XP_016870244 (OMIM: 600456,613886) PREDICTED: BDNF ( 553) 3204 199.3 3.8e-50 XP_016870245 (OMIM: 600456,613886) PREDICTED: BDNF ( 553) 3204 199.3 3.8e-50 NP_001018075 (OMIM: 600456,613886) BDNF/NT-3 growt ( 553) 3204 199.3 3.8e-50 XP_005252063 (OMIM: 600456,613886) PREDICTED: BDNF ( 553) 3204 199.3 3.8e-50 XP_005252061 (OMIM: 600456,613886) PREDICTED: BDNF ( 838) 3204 199.5 5.2e-50 XP_016870240 (OMIM: 600456,613886) PREDICTED: BDNF ( 838) 3204 199.5 5.2e-50 XP_005252058 (OMIM: 600456,613886) PREDICTED: BDNF ( 838) 3204 199.5 5.2e-50 XP_005252060 (OMIM: 600456,613886) PREDICTED: BDNF ( 838) 3204 199.5 5.2e-50 NP_006171 (OMIM: 600456,613886) BDNF/NT-3 growth f ( 838) 3204 199.5 5.2e-50 NP_002521 (OMIM: 191316) NT-3 growth factor recept ( 825) 2118 137.9 1.8e-31 XP_016877729 (OMIM: 191316) PREDICTED: NT-3 growth ( 825) 2118 137.9 1.8e-31 XP_006720606 (OMIM: 191316) PREDICTED: NT-3 growth ( 825) 2118 137.9 1.8e-31 NP_001230030 (OMIM: 191316) NT-3 growth factor rec ( 817) 2104 137.1 3.1e-31 XP_006720607 (OMIM: 191316) PREDICTED: NT-3 growth ( 817) 2104 137.1 3.1e-31 XP_016877741 (OMIM: 191316) PREDICTED: NT-3 growth ( 448) 2079 135.4 5.3e-31 XP_016877740 (OMIM: 191316) PREDICTED: NT-3 growth ( 456) 2074 135.2 6.5e-31 XP_016877732 (OMIM: 191316) PREDICTED: NT-3 growth ( 727) 2074 135.3 9.3e-31 XP_016877735 (OMIM: 191316) PREDICTED: NT-3 growth ( 727) 2074 135.3 9.3e-31 XP_016877733 (OMIM: 191316) PREDICTED: NT-3 growth ( 727) 2074 135.3 9.3e-31 XP_016877734 (OMIM: 191316) PREDICTED: NT-3 growth ( 727) 2074 135.3 9.3e-31 XP_016877730 (OMIM: 191316) PREDICTED: NT-3 growth ( 763) 2074 135.4 9.6e-31 NP_001278866 (OMIM: 600456,613886) BDNF/NT-3 growt ( 464) 1952 128.2 8e-29 NP_001007793 (OMIM: 155240,191315,256800) high aff ( 760) 1622 109.7 5e-23 NP_001012331 (OMIM: 155240,191315,256800) high aff ( 790) 1622 109.7 5.2e-23 NP_002520 (OMIM: 155240,191315,256800) high affini ( 796) 1615 109.3 6.8e-23 XP_006720608 (OMIM: 191316) PREDICTED: NT-3 growth ( 715) 1429 98.7 9.5e-20 XP_016877743 (OMIM: 191316) PREDICTED: NT-3 growth ( 850) 1429 98.8 1.1e-19 XP_016877731 (OMIM: 191316) PREDICTED: NT-3 growth ( 750) 1424 98.5 1.2e-19 NP_001012338 (OMIM: 191316) NT-3 growth factor rec ( 839) 1425 98.6 1.3e-19 XP_016877742 (OMIM: 191316) PREDICTED: NT-3 growth ( 839) 1425 98.6 1.3e-19 NP_001307064 (OMIM: 191316) NT-3 growth factor rec ( 617) 1385 96.2 4.8e-19 XP_006720613 (OMIM: 191316) PREDICTED: NT-3 growth ( 495) 861 66.4 3.6e-10 XP_011519940 (OMIM: 191316) PREDICTED: NT-3 growth ( 469) 849 65.7 5.6e-10 XP_016877739 (OMIM: 191316) PREDICTED: NT-3 growth ( 482) 849 65.7 5.7e-10 XP_016856866 (OMIM: 602336) PREDICTED: inactive ty ( 874) 860 66.5 5.8e-10 XP_011539828 (OMIM: 602336) PREDICTED: inactive ty ( 874) 860 66.5 5.8e-10 >>NP_001018074 (OMIM: 600456,613886) BDNF/NT-3 growth fa (822 aa) initn: 5638 init1: 5638 opt: 5638 Z-score: 1765.3 bits: 337.6 E(85289): 1.4e-91 Smith-Waterman score: 5638; 100.0% identity (100.0% similar) in 822 aa overlap (1-822:1-822) 10 20 30 40 50 60 pF1KB8 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGPASVISNDDDSASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGPASVISNDDDSASP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 LHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 VKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQSQMLHIAQQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQSQMLHIAQQI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 AAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWM 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 PPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQ 730 740 750 760 770 780 790 800 810 820 pF1KB8 EVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPVYLDILG :::::::::::::::::::::::::::::::::::::::::: NP_001 EVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPVYLDILG 790 800 810 820 >>XP_016870243 (OMIM: 600456,613886) PREDICTED: BDNF/NT- (822 aa) initn: 5638 init1: 5638 opt: 5638 Z-score: 1765.3 bits: 337.6 E(85289): 1.4e-91 Smith-Waterman score: 5638; 100.0% identity (100.0% similar) in 822 aa overlap (1-822:1-822) 10 20 30 40 50 60 pF1KB8 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGPASVISNDDDSASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGPASVISNDDDSASP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 LHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 VKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQSQMLHIAQQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQSQMLHIAQQI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 AAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWM 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 PPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQ 730 740 750 760 770 780 790 800 810 820 pF1KB8 EVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPVYLDILG :::::::::::::::::::::::::::::::::::::::::: XP_016 EVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPVYLDILG 790 800 810 820 >>XP_016870242 (OMIM: 600456,613886) PREDICTED: BDNF/NT- (822 aa) initn: 5638 init1: 5638 opt: 5638 Z-score: 1765.3 bits: 337.6 E(85289): 1.4e-91 Smith-Waterman score: 5638; 100.0% identity (100.0% similar) in 822 aa overlap (1-822:1-822) 10 20 30 40 50 60 pF1KB8 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGPASVISNDDDSASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGPASVISNDDDSASP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 LHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 VKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQSQMLHIAQQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQSQMLHIAQQI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 AAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWM 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 PPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQ 730 740 750 760 770 780 790 800 810 820 pF1KB8 EVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPVYLDILG :::::::::::::::::::::::::::::::::::::::::: XP_016 EVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPVYLDILG 790 800 810 820 >>XP_016870241 (OMIM: 600456,613886) PREDICTED: BDNF/NT- (822 aa) initn: 5638 init1: 5638 opt: 5638 Z-score: 1765.3 bits: 337.6 E(85289): 1.4e-91 Smith-Waterman score: 5638; 100.0% identity (100.0% similar) in 822 aa overlap (1-822:1-822) 10 20 30 40 50 60 pF1KB8 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGPASVISNDDDSASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGPASVISNDDDSASP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 LHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 VKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQSQMLHIAQQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQSQMLHIAQQI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 AAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWM 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 PPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQ 730 740 750 760 770 780 790 800 810 820 pF1KB8 EVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPVYLDILG :::::::::::::::::::::::::::::::::::::::::: XP_016 EVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPVYLDILG 790 800 810 820 >>XP_011517020 (OMIM: 600456,613886) PREDICTED: BDNF/NT- (822 aa) initn: 5638 init1: 5638 opt: 5638 Z-score: 1765.3 bits: 337.6 E(85289): 1.4e-91 Smith-Waterman score: 5638; 100.0% identity (100.0% similar) in 822 aa overlap (1-822:1-822) 10 20 30 40 50 60 pF1KB8 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGPASVISNDDDSASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGPASVISNDDDSASP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 LHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVL 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHI 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 VKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQSQMLHIAQQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VKFYGVCVEGDPLIMVFEYMKHGDLNKFLRAHGPDAVLMAEGNPPTELTQSQMLHIAQQI 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 AAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDYYRVGGHTMLPIRWM 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 PPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGRVLQRPRTCPQ 730 740 750 760 770 780 790 800 810 820 pF1KB8 EVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPVYLDILG :::::::::::::::::::::::::::::::::::::::::: XP_011 EVYELMLGCWQREPHMRKNIKGIHTLLQNLAKASPVYLDILG 790 800 810 820 >>NP_001018076 (OMIM: 600456,613886) BDNF/NT-3 growth fa (537 aa) initn: 3649 init1: 3621 opt: 3621 Z-score: 1149.3 bits: 223.0 E(85289): 2.8e-57 Smith-Waterman score: 3621; 99.8% identity (100.0% similar) in 529 aa overlap (1-529:1-529) 10 20 30 40 50 60 pF1KB8 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGPASVISNDDDSASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGPASVISNDDDSASP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 LHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVL ::::::::::::::::::::::::::::::::::::::::::::::::. NP_001 LHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTWPRGSPKTA 490 500 510 520 530 550 560 570 580 590 600 pF1KB8 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHI >>XP_016870246 (OMIM: 600456,613886) PREDICTED: BDNF/NT- (537 aa) initn: 3649 init1: 3621 opt: 3621 Z-score: 1149.3 bits: 223.0 E(85289): 2.8e-57 Smith-Waterman score: 3621; 99.8% identity (100.0% similar) in 529 aa overlap (1-529:1-529) 10 20 30 40 50 60 pF1KB8 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGPASVISNDDDSASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGPASVISNDDDSASP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 LHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVL ::::::::::::::::::::::::::::::::::::::::::::::::. XP_016 LHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTWPRGSPKTA 490 500 510 520 530 550 560 570 580 590 600 pF1KB8 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHI >>XP_011517022 (OMIM: 600456,613886) PREDICTED: BDNF/NT- (537 aa) initn: 3649 init1: 3621 opt: 3621 Z-score: 1149.3 bits: 223.0 E(85289): 2.8e-57 Smith-Waterman score: 3621; 99.8% identity (100.0% similar) in 529 aa overlap (1-529:1-529) 10 20 30 40 50 60 pF1KB8 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGPASVISNDDDSASP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGPASVISNDDDSASP 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 LHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVL ::::::::::::::::::::::::::::::::::::::::::::::::. XP_011 LHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTWPRGSPKTA 490 500 510 520 530 550 560 570 580 590 600 pF1KB8 KRELGEGAFGKVFLAECYNLCPEQDKILVAVKTLKDASDNARKDFHREAELLTNLQHEHI >>XP_016870247 (OMIM: 600456,613886) PREDICTED: BDNF/NT- (477 aa) initn: 3209 init1: 3209 opt: 3209 Z-score: 1023.7 bits: 199.6 E(85289): 2.8e-50 Smith-Waterman score: 3209; 100.0% identity (100.0% similar) in 466 aa overlap (1-466:1-466) 10 20 30 40 50 60 pF1KB8 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGPASVISNDDDSASP :::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGFVLFHKIPLDG 430 440 450 460 470 490 500 510 520 530 540 pF1KB8 LHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVL >>XP_016870250 (OMIM: 600456,613886) PREDICTED: BDNF/NT- (477 aa) initn: 3209 init1: 3209 opt: 3209 Z-score: 1023.7 bits: 199.6 E(85289): 2.8e-50 Smith-Waterman score: 3209; 100.0% identity (100.0% similar) in 466 aa overlap (1-466:1-466) 10 20 30 40 50 60 pF1KB8 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSWIRWHGPAMARLWGFCWLVVGFWRAAFACPTSCKCSASRIWCSDPSPGIVAFPRLEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSVDPENITEIFIANQKRLEIINEDDVEAYVGLRNLTIVDSGLKFVAHKAFLKNSNLQHI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NFTRNKLTSLSRKHFRHLDLSELILVGNPFTCSCDIMWIKTLQEAKSSPDTQDLYCLNES 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKNIPLANLQIPNCGLPSANLAAPNLTVEEGKSITLSCSVAGDPVPNMYWDVGNLVSKHM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NETSHTQGSLRITNISSDDSGKQISCVAENLVGEDQDSVNLTVHFAPTITFLESPTSDHH 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WCIPFTVKGNPKPALQWFYNGAILNESKYICTKIHVTNHTEYHGCLQLDNPTHMNNGDYT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIAKNEYGKDEKQISAHFMGWPGIDDGANPNYPDVIYEDYGTAANDIGDTTNRSNEIPST 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGPASVISNDDDSASP :::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVTDKTGREHLSVYAVVVIASVVGFCLLVMLFLLKLARHSKFGMKGFVLFHKIPLDG 430 440 450 460 470 490 500 510 520 530 540 pF1KB8 LHHISNGSNTPSSSEGGPDAVIIGMTKIPVIENPQYFGITNSQLKPDTFVQHIKRHNIVL 822 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sun Nov 6 19:58:15 2016 done: Sun Nov 6 19:58:17 2016 Total Scan time: 12.540 Total Display time: 0.230 Function used was FASTA [36.3.4 Apr, 2011]