Result of FASTA (omim) for
pF1KB8476
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8476, 846 aa
1>>>pF1KB8476 846 - 846 aa - 846 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.6882+/-0.000659; mu= -9.3063+/- 0.041
mean_var=639.5997+/-142.580, 0's: 0 Z-trim(117.2): 1593 B-trim: 0 in 0/50
Lambda= 0.050713
statistics sampled from 26792 (28933) to 26792 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.666), E-opt: 0.2 (0.339), width: 16
Scan time: 13.230
The best scores are: opt bits E(85289)
NP_942089 (OMIM: 604923) mitogen-activated protein ( 846) 5728 435.8 3.8e-121
NP_006566 (OMIM: 604923) mitogen-activated protein ( 846) 5728 435.8 3.8e-121
XP_006720076 (OMIM: 604923) PREDICTED: mitogen-act ( 846) 5728 435.8 3.8e-121
XP_011534679 (OMIM: 604923) PREDICTED: mitogen-act ( 845) 5710 434.5 9.6e-121
XP_011534680 (OMIM: 604923) PREDICTED: mitogen-act ( 779) 5289 403.7 1.7e-111
XP_011534681 (OMIM: 604923) PREDICTED: mitogen-act ( 710) 4803 368.1 8.2e-101
XP_011534682 (OMIM: 604923) PREDICTED: mitogen-act ( 557) 3451 269.0 4.2e-71
NP_001257354 (OMIM: 604921) mitogen-activated prot ( 873) 1935 158.3 1.4e-37
NP_003609 (OMIM: 604921) mitogen-activated protein ( 894) 1902 155.9 7.3e-37
NP_001036065 (OMIM: 601983) mitogen-activated prot ( 821) 1689 140.3 3.4e-32
NP_009112 (OMIM: 601983) mitogen-activated protein ( 833) 1689 140.3 3.4e-32
XP_016873585 (OMIM: 603166) PREDICTED: mitogen-act ( 584) 1561 130.7 1.8e-29
XP_011543505 (OMIM: 603166) PREDICTED: mitogen-act ( 797) 1561 130.9 2.2e-29
NP_001294919 (OMIM: 603166) mitogen-activated prot ( 812) 1561 130.9 2.2e-29
NP_004570 (OMIM: 603166) mitogen-activated protein ( 820) 1561 130.9 2.3e-29
XP_011524706 (OMIM: 601983) PREDICTED: mitogen-act ( 861) 1452 123.0 5.8e-27
XP_011524705 (OMIM: 601983) PREDICTED: mitogen-act ( 873) 1452 123.0 5.9e-27
XP_016873583 (OMIM: 603166) PREDICTED: mitogen-act ( 643) 1379 117.5 2e-25
XP_016873582 (OMIM: 603166) PREDICTED: mitogen-act ( 768) 1379 117.6 2.2e-25
XP_011543506 (OMIM: 603166) PREDICTED: mitogen-act ( 776) 1379 117.6 2.2e-25
XP_016881720 (OMIM: 601983) PREDICTED: mitogen-act ( 860) 1341 114.9 1.6e-24
XP_011508795 (OMIM: 602255) PREDICTED: serine/thre ( 376) 899 82.1 5.4e-15
XP_011508798 (OMIM: 602255) PREDICTED: serine/thre ( 334) 897 81.8 5.6e-15
NP_001258906 (OMIM: 602255) serine/threonine-prote ( 426) 899 82.1 5.8e-15
NP_006365 (OMIM: 602255) serine/threonine-protein ( 426) 899 82.1 5.8e-15
NP_001258907 (OMIM: 602255) serine/threonine-prote ( 426) 899 82.1 5.8e-15
XP_016858657 (OMIM: 602255) PREDICTED: serine/thre ( 365) 897 81.9 5.9e-15
XP_016858658 (OMIM: 602255) PREDICTED: serine/thre ( 365) 897 81.9 5.9e-15
XP_016873584 (OMIM: 603166) PREDICTED: mitogen-act ( 620) 897 82.2 8e-15
NP_001027467 (OMIM: 604984) serine/threonine-prote ( 431) 867 79.8 3e-14
NP_057626 (OMIM: 300547) serine/threonine-protein ( 416) 865 79.6 3.2e-14
XP_016869247 (OMIM: 605030) PREDICTED: serine/thre ( 456) 863 79.5 3.8e-14
NP_006272 (OMIM: 605030) serine/threonine-protein ( 491) 863 79.6 3.9e-14
NP_001155038 (OMIM: 610005,617028) TRAF2 and NCK-i (1268) 874 80.9 3.9e-14
NP_001155037 (OMIM: 610005,617028) TRAF2 and NCK-i (1276) 874 80.9 4e-14
NP_001155036 (OMIM: 610005,617028) TRAF2 and NCK-i (1297) 874 81.0 4e-14
NP_001155035 (OMIM: 610005,617028) TRAF2 and NCK-i (1305) 874 81.0 4e-14
NP_001155034 (OMIM: 610005,617028) TRAF2 and NCK-i (1323) 874 81.0 4e-14
NP_001155033 (OMIM: 610005,617028) TRAF2 and NCK-i (1331) 874 81.0 4.1e-14
XP_011515553 (OMIM: 605030) PREDICTED: serine/thre ( 522) 863 79.6 4.1e-14
NP_003567 (OMIM: 604984) serine/threonine-protein ( 443) 861 79.4 4.1e-14
NP_001155032 (OMIM: 610005,617028) TRAF2 and NCK-i (1352) 874 81.0 4.1e-14
NP_055843 (OMIM: 610005,617028) TRAF2 and NCK-inte (1360) 874 81.0 4.1e-14
XP_016876284 (OMIM: 604984) PREDICTED: serine/thre ( 474) 861 79.4 4.3e-14
XP_016876283 (OMIM: 604984) PREDICTED: serine/thre ( 517) 861 79.5 4.5e-14
NP_001243241 (OMIM: 605030) serine/threonine-prote ( 519) 861 79.5 4.5e-14
XP_016869246 (OMIM: 605030) PREDICTED: serine/thre ( 524) 861 79.5 4.5e-14
XP_016860864 (OMIM: 604666) PREDICTED: mitogen-act (1155) 870 80.6 4.6e-14
XP_016860863 (OMIM: 604666) PREDICTED: mitogen-act (1158) 870 80.6 4.6e-14
XP_016860862 (OMIM: 604666) PREDICTED: mitogen-act (1163) 870 80.6 4.6e-14
>>NP_942089 (OMIM: 604923) mitogen-activated protein kin (846 aa)
initn: 5728 init1: 5728 opt: 5728 Z-score: 2295.9 bits: 435.8 E(85289): 3.8e-121
Smith-Waterman score: 5728; 100.0% identity (100.0% similar) in 846 aa overlap (1-846:1-846)
10 20 30 40 50 60
pF1KB8 MEAPLRPAADILRRNPQQDYELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 MEAPLRPAADILRRNPQQDYELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LIQQEIFMVKECKHCNIVAYFGSYLSREKLWICMEYCGGGSLQDIYHVTGPLSELQIAYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 LIQQEIFMVKECKHCNIVAYFGSYLSREKLWICMEYCGGGSLQDIYHVTGPLSELQIAYV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 CRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 CRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 WMAPEVAAVEKNGGYNQLCDIWAVGITAIELGELQPPMFDLHPMRALFLMSKSNFQPPKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 WMAPEVAAVEKNGGYNQLCDIWAVGITAIELGELQPPMFDLHPMRALFLMSKSNFQPPKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 KDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFVAQPGLSRALAVELLDKVNNPDNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 KDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFVAQPGLSRALAVELLDKVNNPDNH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 AHYTEADDDDFEPHAIIRHTIRSTNRNARAERTASEINFDKLQFEPPLRKETEARDEMGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 AHYTEADDDDFEPHAIIRHTIRSTNRNARAERTASEINFDKLQFEPPLRKETEARDEMGL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SSDPNFMLQWNPFVDGANTGKSTSKRAIPPPLPPKPRISSYPEDNFPDEEKASTIKHCPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 SSDPNFMLQWNPFVDGANTGKSTSKRAIPPPLPPKPRISSYPEDNFPDEEKASTIKHCPD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SESRAPQILRRQSSPSCGPVAETSSIGNGDGISKLMSENTEGSAQAPQLPRKKDKRDFPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 SESRAPQILRRQSSPSCGPVAETSSIGNGDGISKLMSENTEGSAQAPQLPRKKDKRDFPK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 PAINGLPPTPKVLMGACFSKVFDGCPLKINCATSWIHPDTKDQYIIFGTEDGIYTLNLNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 PAINGLPPTPKVLMGACFSKVFDGCPLKINCATSWIHPDTKDQYIIFGTEDGIYTLNLNE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 LHEATMEQLFPRKCTWLYVINNTLMSLSEGKTFQLYSHNLIALFEHAKKPGLAAHIQTHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 LHEATMEQLFPRKCTWLYVINNTLMSLSEGKTFQLYSHNLIALFEHAKKPGLAAHIQTHR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 FPDRILPRKFALTTKIPDTKGCHKCCIVRNPYTGHKYLCGALQSGIVLLQWYEPMQKFML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 FPDRILPRKFALTTKIPDTKGCHKCCIVRNPYTGHKYLCGALQSGIVLLQWYEPMQKFML
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 IKHFDFPLPSPLNVFEMLVIPEQEYPMVCVAISKGTESNQVVQFETINLNSASSWFTEIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 IKHFDFPLPSPLNVFEMLVIPEQEYPMVCVAISKGTESNQVVQFETINLNSASSWFTEIG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 AGSQQLDSIHVTQLERDTVLVCLDKFVKIVNLQGKLKSSKKLASELSFDFRIESVVCLQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 AGSQQLDSIHVTQLERDTVLVCLDKFVKIVNLQGKLKSSKKLASELSFDFRIESVVCLQD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 SVLAFWKHGMQGKSFKSDEVTQEISDETRVFRLLGSDRVVVLESRPTENPTAHSNLYILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_942 SVLAFWKHGMQGKSFKSDEVTQEISDETRVFRLLGSDRVVVLESRPTENPTAHSNLYILA
790 800 810 820 830 840
pF1KB8 GHENSY
::::::
NP_942 GHENSY
>>NP_006566 (OMIM: 604923) mitogen-activated protein kin (846 aa)
initn: 5728 init1: 5728 opt: 5728 Z-score: 2295.9 bits: 435.8 E(85289): 3.8e-121
Smith-Waterman score: 5728; 100.0% identity (100.0% similar) in 846 aa overlap (1-846:1-846)
10 20 30 40 50 60
pF1KB8 MEAPLRPAADILRRNPQQDYELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MEAPLRPAADILRRNPQQDYELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LIQQEIFMVKECKHCNIVAYFGSYLSREKLWICMEYCGGGSLQDIYHVTGPLSELQIAYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LIQQEIFMVKECKHCNIVAYFGSYLSREKLWICMEYCGGGSLQDIYHVTGPLSELQIAYV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 CRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 CRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 WMAPEVAAVEKNGGYNQLCDIWAVGITAIELGELQPPMFDLHPMRALFLMSKSNFQPPKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 WMAPEVAAVEKNGGYNQLCDIWAVGITAIELGELQPPMFDLHPMRALFLMSKSNFQPPKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 KDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFVAQPGLSRALAVELLDKVNNPDNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFVAQPGLSRALAVELLDKVNNPDNH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 AHYTEADDDDFEPHAIIRHTIRSTNRNARAERTASEINFDKLQFEPPLRKETEARDEMGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AHYTEADDDDFEPHAIIRHTIRSTNRNARAERTASEINFDKLQFEPPLRKETEARDEMGL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SSDPNFMLQWNPFVDGANTGKSTSKRAIPPPLPPKPRISSYPEDNFPDEEKASTIKHCPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SSDPNFMLQWNPFVDGANTGKSTSKRAIPPPLPPKPRISSYPEDNFPDEEKASTIKHCPD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SESRAPQILRRQSSPSCGPVAETSSIGNGDGISKLMSENTEGSAQAPQLPRKKDKRDFPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SESRAPQILRRQSSPSCGPVAETSSIGNGDGISKLMSENTEGSAQAPQLPRKKDKRDFPK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 PAINGLPPTPKVLMGACFSKVFDGCPLKINCATSWIHPDTKDQYIIFGTEDGIYTLNLNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PAINGLPPTPKVLMGACFSKVFDGCPLKINCATSWIHPDTKDQYIIFGTEDGIYTLNLNE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 LHEATMEQLFPRKCTWLYVINNTLMSLSEGKTFQLYSHNLIALFEHAKKPGLAAHIQTHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LHEATMEQLFPRKCTWLYVINNTLMSLSEGKTFQLYSHNLIALFEHAKKPGLAAHIQTHR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 FPDRILPRKFALTTKIPDTKGCHKCCIVRNPYTGHKYLCGALQSGIVLLQWYEPMQKFML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FPDRILPRKFALTTKIPDTKGCHKCCIVRNPYTGHKYLCGALQSGIVLLQWYEPMQKFML
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 IKHFDFPLPSPLNVFEMLVIPEQEYPMVCVAISKGTESNQVVQFETINLNSASSWFTEIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IKHFDFPLPSPLNVFEMLVIPEQEYPMVCVAISKGTESNQVVQFETINLNSASSWFTEIG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 AGSQQLDSIHVTQLERDTVLVCLDKFVKIVNLQGKLKSSKKLASELSFDFRIESVVCLQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AGSQQLDSIHVTQLERDTVLVCLDKFVKIVNLQGKLKSSKKLASELSFDFRIESVVCLQD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 SVLAFWKHGMQGKSFKSDEVTQEISDETRVFRLLGSDRVVVLESRPTENPTAHSNLYILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SVLAFWKHGMQGKSFKSDEVTQEISDETRVFRLLGSDRVVVLESRPTENPTAHSNLYILA
790 800 810 820 830 840
pF1KB8 GHENSY
::::::
NP_006 GHENSY
>>XP_006720076 (OMIM: 604923) PREDICTED: mitogen-activat (846 aa)
initn: 5728 init1: 5728 opt: 5728 Z-score: 2295.9 bits: 435.8 E(85289): 3.8e-121
Smith-Waterman score: 5728; 100.0% identity (100.0% similar) in 846 aa overlap (1-846:1-846)
10 20 30 40 50 60
pF1KB8 MEAPLRPAADILRRNPQQDYELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MEAPLRPAADILRRNPQQDYELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LIQQEIFMVKECKHCNIVAYFGSYLSREKLWICMEYCGGGSLQDIYHVTGPLSELQIAYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LIQQEIFMVKECKHCNIVAYFGSYLSREKLWICMEYCGGGSLQDIYHVTGPLSELQIAYV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 CRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 WMAPEVAAVEKNGGYNQLCDIWAVGITAIELGELQPPMFDLHPMRALFLMSKSNFQPPKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WMAPEVAAVEKNGGYNQLCDIWAVGITAIELGELQPPMFDLHPMRALFLMSKSNFQPPKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 KDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFVAQPGLSRALAVELLDKVNNPDNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFVAQPGLSRALAVELLDKVNNPDNH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 AHYTEADDDDFEPHAIIRHTIRSTNRNARAERTASEINFDKLQFEPPLRKETEARDEMGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AHYTEADDDDFEPHAIIRHTIRSTNRNARAERTASEINFDKLQFEPPLRKETEARDEMGL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SSDPNFMLQWNPFVDGANTGKSTSKRAIPPPLPPKPRISSYPEDNFPDEEKASTIKHCPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSDPNFMLQWNPFVDGANTGKSTSKRAIPPPLPPKPRISSYPEDNFPDEEKASTIKHCPD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SESRAPQILRRQSSPSCGPVAETSSIGNGDGISKLMSENTEGSAQAPQLPRKKDKRDFPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SESRAPQILRRQSSPSCGPVAETSSIGNGDGISKLMSENTEGSAQAPQLPRKKDKRDFPK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 PAINGLPPTPKVLMGACFSKVFDGCPLKINCATSWIHPDTKDQYIIFGTEDGIYTLNLNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PAINGLPPTPKVLMGACFSKVFDGCPLKINCATSWIHPDTKDQYIIFGTEDGIYTLNLNE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 LHEATMEQLFPRKCTWLYVINNTLMSLSEGKTFQLYSHNLIALFEHAKKPGLAAHIQTHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LHEATMEQLFPRKCTWLYVINNTLMSLSEGKTFQLYSHNLIALFEHAKKPGLAAHIQTHR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 FPDRILPRKFALTTKIPDTKGCHKCCIVRNPYTGHKYLCGALQSGIVLLQWYEPMQKFML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FPDRILPRKFALTTKIPDTKGCHKCCIVRNPYTGHKYLCGALQSGIVLLQWYEPMQKFML
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 IKHFDFPLPSPLNVFEMLVIPEQEYPMVCVAISKGTESNQVVQFETINLNSASSWFTEIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IKHFDFPLPSPLNVFEMLVIPEQEYPMVCVAISKGTESNQVVQFETINLNSASSWFTEIG
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 AGSQQLDSIHVTQLERDTVLVCLDKFVKIVNLQGKLKSSKKLASELSFDFRIESVVCLQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AGSQQLDSIHVTQLERDTVLVCLDKFVKIVNLQGKLKSSKKLASELSFDFRIESVVCLQD
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 SVLAFWKHGMQGKSFKSDEVTQEISDETRVFRLLGSDRVVVLESRPTENPTAHSNLYILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVLAFWKHGMQGKSFKSDEVTQEISDETRVFRLLGSDRVVVLESRPTENPTAHSNLYILA
790 800 810 820 830 840
pF1KB8 GHENSY
::::::
XP_006 GHENSY
>>XP_011534679 (OMIM: 604923) PREDICTED: mitogen-activat (845 aa)
initn: 5708 init1: 3870 opt: 5710 Z-score: 2288.7 bits: 434.5 E(85289): 9.6e-121
Smith-Waterman score: 5710; 99.9% identity (99.9% similar) in 846 aa overlap (1-846:1-845)
10 20 30 40 50 60
pF1KB8 MEAPLRPAADILRRNPQQDYELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEAPLRPAADILRRNPQQDYELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LIQQEIFMVKECKHCNIVAYFGSYLSREKLWICMEYCGGGSLQDIYHVTGPLSELQIAYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIQQEIFMVKECKHCNIVAYFGSYLSREKLWICMEYCGGGSLQDIYHVTGPLSELQIAYV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 CRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 WMAPEVAAVEKNGGYNQLCDIWAVGITAIELGELQPPMFDLHPMRALFLMSKSNFQPPKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WMAPEVAAVEKNGGYNQLCDIWAVGITAIELGELQPPMFDLHPMRALFLMSKSNFQPPKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 KDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFVAQPGLSRALAVELLDKVNNPDNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFVAQPGLSRALAVELLDKVNNPDNH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 AHYTEADDDDFEPHAIIRHTIRSTNRNARAERTASEINFDKLQFEPPLRKETEARDEMGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHYTEADDDDFEPHAIIRHTIRSTNRNARAERTASEINFDKLQFEPPLRKETEARDEMGL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SSDPNFMLQWNPFVDGANTGKSTSKRAIPPPLPPKPRISSYPEDNFPDEEKASTIKHCPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSDPNFMLQWNPFVDGANTGKSTSKRAIPPPLPPKPRISSYPEDNFPDEEKASTIKHCPD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SESRAPQILRRQSSPSCGPVAETSSIGNGDGISKLMSENTEGSAQAPQLPRKKDKRDFPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SESRAPQILRRQSSPSCGPVAETSSIGNGDGISKLMSENTEGSAQAPQLPRKKDKRDFPK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 PAINGLPPTPKVLMGACFSKVFDGCPLKINCATSWIHPDTKDQYIIFGTEDGIYTLNLNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAINGLPPTPKVLMGACFSKVFDGCPLKINCATSWIHPDTKDQYIIFGTEDGIYTLNLNE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 LHEATMEQLFPRKCTWLYVINNTLMSLSEGKTFQLYSHNLIALFEHAKKPGLAAHIQTHR
:::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::
XP_011 LHEATMEQLFPRKCTWLYVINNTLMSLS-GKTFQLYSHNLIALFEHAKKPGLAAHIQTHR
550 560 570 580 590
610 620 630 640 650 660
pF1KB8 FPDRILPRKFALTTKIPDTKGCHKCCIVRNPYTGHKYLCGALQSGIVLLQWYEPMQKFML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPDRILPRKFALTTKIPDTKGCHKCCIVRNPYTGHKYLCGALQSGIVLLQWYEPMQKFML
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB8 IKHFDFPLPSPLNVFEMLVIPEQEYPMVCVAISKGTESNQVVQFETINLNSASSWFTEIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKHFDFPLPSPLNVFEMLVIPEQEYPMVCVAISKGTESNQVVQFETINLNSASSWFTEIG
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB8 AGSQQLDSIHVTQLERDTVLVCLDKFVKIVNLQGKLKSSKKLASELSFDFRIESVVCLQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGSQQLDSIHVTQLERDTVLVCLDKFVKIVNLQGKLKSSKKLASELSFDFRIESVVCLQD
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB8 SVLAFWKHGMQGKSFKSDEVTQEISDETRVFRLLGSDRVVVLESRPTENPTAHSNLYILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVLAFWKHGMQGKSFKSDEVTQEISDETRVFRLLGSDRVVVLESRPTENPTAHSNLYILA
780 790 800 810 820 830
pF1KB8 GHENSY
::::::
XP_011 GHENSY
840
>>XP_011534680 (OMIM: 604923) PREDICTED: mitogen-activat (779 aa)
initn: 5289 init1: 5289 opt: 5289 Z-score: 2122.7 bits: 403.7 E(85289): 1.7e-111
Smith-Waterman score: 5289; 100.0% identity (100.0% similar) in 779 aa overlap (68-846:1-779)
40 50 60 70 80 90
pF1KB8 RNVHTGELAAVKIIKLEPGDDFSLIQQEIFMVKECKHCNIVAYFGSYLSREKLWICMEYC
::::::::::::::::::::::::::::::
XP_011 MVKECKHCNIVAYFGSYLSREKLWICMEYC
10 20 30
100 110 120 130 140 150
pF1KB8 GGGSLQDIYHVTGPLSELQIAYVCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGGSLQDIYHVTGPLSELQIAYVCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLA
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB8 DFGVAAKITATIAKRKSFIGTPYWMAPEVAAVEKNGGYNQLCDIWAVGITAIELGELQPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFGVAAKITATIAKRKSFIGTPYWMAPEVAAVEKNGGYNQLCDIWAVGITAIELGELQPP
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB8 MFDLHPMRALFLMSKSNFQPPKLKDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MFDLHPMRALFLMSKSNFQPPKLKDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFV
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB8 AQPGLSRALAVELLDKVNNPDNHAHYTEADDDDFEPHAIIRHTIRSTNRNARAERTASEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQPGLSRALAVELLDKVNNPDNHAHYTEADDDDFEPHAIIRHTIRSTNRNARAERTASEI
220 230 240 250 260 270
340 350 360 370 380 390
pF1KB8 NFDKLQFEPPLRKETEARDEMGLSSDPNFMLQWNPFVDGANTGKSTSKRAIPPPLPPKPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFDKLQFEPPLRKETEARDEMGLSSDPNFMLQWNPFVDGANTGKSTSKRAIPPPLPPKPR
280 290 300 310 320 330
400 410 420 430 440 450
pF1KB8 ISSYPEDNFPDEEKASTIKHCPDSESRAPQILRRQSSPSCGPVAETSSIGNGDGISKLMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISSYPEDNFPDEEKASTIKHCPDSESRAPQILRRQSSPSCGPVAETSSIGNGDGISKLMS
340 350 360 370 380 390
460 470 480 490 500 510
pF1KB8 ENTEGSAQAPQLPRKKDKRDFPKPAINGLPPTPKVLMGACFSKVFDGCPLKINCATSWIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENTEGSAQAPQLPRKKDKRDFPKPAINGLPPTPKVLMGACFSKVFDGCPLKINCATSWIH
400 410 420 430 440 450
520 530 540 550 560 570
pF1KB8 PDTKDQYIIFGTEDGIYTLNLNELHEATMEQLFPRKCTWLYVINNTLMSLSEGKTFQLYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDTKDQYIIFGTEDGIYTLNLNELHEATMEQLFPRKCTWLYVINNTLMSLSEGKTFQLYS
460 470 480 490 500 510
580 590 600 610 620 630
pF1KB8 HNLIALFEHAKKPGLAAHIQTHRFPDRILPRKFALTTKIPDTKGCHKCCIVRNPYTGHKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HNLIALFEHAKKPGLAAHIQTHRFPDRILPRKFALTTKIPDTKGCHKCCIVRNPYTGHKY
520 530 540 550 560 570
640 650 660 670 680 690
pF1KB8 LCGALQSGIVLLQWYEPMQKFMLIKHFDFPLPSPLNVFEMLVIPEQEYPMVCVAISKGTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCGALQSGIVLLQWYEPMQKFMLIKHFDFPLPSPLNVFEMLVIPEQEYPMVCVAISKGTE
580 590 600 610 620 630
700 710 720 730 740 750
pF1KB8 SNQVVQFETINLNSASSWFTEIGAGSQQLDSIHVTQLERDTVLVCLDKFVKIVNLQGKLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNQVVQFETINLNSASSWFTEIGAGSQQLDSIHVTQLERDTVLVCLDKFVKIVNLQGKLK
640 650 660 670 680 690
760 770 780 790 800 810
pF1KB8 SSKKLASELSFDFRIESVVCLQDSVLAFWKHGMQGKSFKSDEVTQEISDETRVFRLLGSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSKKLASELSFDFRIESVVCLQDSVLAFWKHGMQGKSFKSDEVTQEISDETRVFRLLGSD
700 710 720 730 740 750
820 830 840
pF1KB8 RVVVLESRPTENPTAHSNLYILAGHENSY
:::::::::::::::::::::::::::::
XP_011 RVVVLESRPTENPTAHSNLYILAGHENSY
760 770
>>XP_011534681 (OMIM: 604923) PREDICTED: mitogen-activat (710 aa)
initn: 4803 init1: 4803 opt: 4803 Z-score: 1930.9 bits: 368.1 E(85289): 8.2e-101
Smith-Waterman score: 4803; 100.0% identity (100.0% similar) in 710 aa overlap (137-846:1-710)
110 120 130 140 150 160
pF1KB8 HVTGPLSELQIAYVCRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKIT
::::::::::::::::::::::::::::::
XP_011 MHRDIKGANILLTDHGDVKLADFGVAAKIT
10 20 30
170 180 190 200 210 220
pF1KB8 ATIAKRKSFIGTPYWMAPEVAAVEKNGGYNQLCDIWAVGITAIELGELQPPMFDLHPMRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATIAKRKSFIGTPYWMAPEVAAVEKNGGYNQLCDIWAVGITAIELGELQPPMFDLHPMRA
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB8 LFLMSKSNFQPPKLKDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFVAQPGLSRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFLMSKSNFQPPKLKDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFVAQPGLSRAL
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB8 AVELLDKVNNPDNHAHYTEADDDDFEPHAIIRHTIRSTNRNARAERTASEINFDKLQFEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVELLDKVNNPDNHAHYTEADDDDFEPHAIIRHTIRSTNRNARAERTASEINFDKLQFEP
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB8 PLRKETEARDEMGLSSDPNFMLQWNPFVDGANTGKSTSKRAIPPPLPPKPRISSYPEDNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLRKETEARDEMGLSSDPNFMLQWNPFVDGANTGKSTSKRAIPPPLPPKPRISSYPEDNF
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB8 PDEEKASTIKHCPDSESRAPQILRRQSSPSCGPVAETSSIGNGDGISKLMSENTEGSAQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDEEKASTIKHCPDSESRAPQILRRQSSPSCGPVAETSSIGNGDGISKLMSENTEGSAQA
280 290 300 310 320 330
470 480 490 500 510 520
pF1KB8 PQLPRKKDKRDFPKPAINGLPPTPKVLMGACFSKVFDGCPLKINCATSWIHPDTKDQYII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PQLPRKKDKRDFPKPAINGLPPTPKVLMGACFSKVFDGCPLKINCATSWIHPDTKDQYII
340 350 360 370 380 390
530 540 550 560 570 580
pF1KB8 FGTEDGIYTLNLNELHEATMEQLFPRKCTWLYVINNTLMSLSEGKTFQLYSHNLIALFEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FGTEDGIYTLNLNELHEATMEQLFPRKCTWLYVINNTLMSLSEGKTFQLYSHNLIALFEH
400 410 420 430 440 450
590 600 610 620 630 640
pF1KB8 AKKPGLAAHIQTHRFPDRILPRKFALTTKIPDTKGCHKCCIVRNPYTGHKYLCGALQSGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AKKPGLAAHIQTHRFPDRILPRKFALTTKIPDTKGCHKCCIVRNPYTGHKYLCGALQSGI
460 470 480 490 500 510
650 660 670 680 690 700
pF1KB8 VLLQWYEPMQKFMLIKHFDFPLPSPLNVFEMLVIPEQEYPMVCVAISKGTESNQVVQFET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLLQWYEPMQKFMLIKHFDFPLPSPLNVFEMLVIPEQEYPMVCVAISKGTESNQVVQFET
520 530 540 550 560 570
710 720 730 740 750 760
pF1KB8 INLNSASSWFTEIGAGSQQLDSIHVTQLERDTVLVCLDKFVKIVNLQGKLKSSKKLASEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 INLNSASSWFTEIGAGSQQLDSIHVTQLERDTVLVCLDKFVKIVNLQGKLKSSKKLASEL
580 590 600 610 620 630
770 780 790 800 810 820
pF1KB8 SFDFRIESVVCLQDSVLAFWKHGMQGKSFKSDEVTQEISDETRVFRLLGSDRVVVLESRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFDFRIESVVCLQDSVLAFWKHGMQGKSFKSDEVTQEISDETRVFRLLGSDRVVVLESRP
640 650 660 670 680 690
830 840
pF1KB8 TENPTAHSNLYILAGHENSY
::::::::::::::::::::
XP_011 TENPTAHSNLYILAGHENSY
700 710
>>XP_011534682 (OMIM: 604923) PREDICTED: mitogen-activat (557 aa)
initn: 3451 init1: 3451 opt: 3451 Z-score: 1397.4 bits: 269.0 E(85289): 4.2e-71
Smith-Waterman score: 3451; 99.8% identity (100.0% similar) in 508 aa overlap (339-846:50-557)
310 320 330 340 350 360
pF1KB8 DDFEPHAIIRHTIRSTNRNARAERTASEINFDKLQFEPPLRKETEARDEMGLSSDPNFML
.:::::::::::::::::::::::::::::
XP_011 DSSYIRKNTECCLQVVEALYSHYTLLHVSTLDKLQFEPPLRKETEARDEMGLSSDPNFML
20 30 40 50 60 70
370 380 390 400 410 420
pF1KB8 QWNPFVDGANTGKSTSKRAIPPPLPPKPRISSYPEDNFPDEEKASTIKHCPDSESRAPQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QWNPFVDGANTGKSTSKRAIPPPLPPKPRISSYPEDNFPDEEKASTIKHCPDSESRAPQI
80 90 100 110 120 130
430 440 450 460 470 480
pF1KB8 LRRQSSPSCGPVAETSSIGNGDGISKLMSENTEGSAQAPQLPRKKDKRDFPKPAINGLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRQSSPSCGPVAETSSIGNGDGISKLMSENTEGSAQAPQLPRKKDKRDFPKPAINGLPP
140 150 160 170 180 190
490 500 510 520 530 540
pF1KB8 TPKVLMGACFSKVFDGCPLKINCATSWIHPDTKDQYIIFGTEDGIYTLNLNELHEATMEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPKVLMGACFSKVFDGCPLKINCATSWIHPDTKDQYIIFGTEDGIYTLNLNELHEATMEQ
200 210 220 230 240 250
550 560 570 580 590 600
pF1KB8 LFPRKCTWLYVINNTLMSLSEGKTFQLYSHNLIALFEHAKKPGLAAHIQTHRFPDRILPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFPRKCTWLYVINNTLMSLSEGKTFQLYSHNLIALFEHAKKPGLAAHIQTHRFPDRILPR
260 270 280 290 300 310
610 620 630 640 650 660
pF1KB8 KFALTTKIPDTKGCHKCCIVRNPYTGHKYLCGALQSGIVLLQWYEPMQKFMLIKHFDFPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KFALTTKIPDTKGCHKCCIVRNPYTGHKYLCGALQSGIVLLQWYEPMQKFMLIKHFDFPL
320 330 340 350 360 370
670 680 690 700 710 720
pF1KB8 PSPLNVFEMLVIPEQEYPMVCVAISKGTESNQVVQFETINLNSASSWFTEIGAGSQQLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSPLNVFEMLVIPEQEYPMVCVAISKGTESNQVVQFETINLNSASSWFTEIGAGSQQLDS
380 390 400 410 420 430
730 740 750 760 770 780
pF1KB8 IHVTQLERDTVLVCLDKFVKIVNLQGKLKSSKKLASELSFDFRIESVVCLQDSVLAFWKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHVTQLERDTVLVCLDKFVKIVNLQGKLKSSKKLASELSFDFRIESVVCLQDSVLAFWKH
440 450 460 470 480 490
790 800 810 820 830 840
pF1KB8 GMQGKSFKSDEVTQEISDETRVFRLLGSDRVVVLESRPTENPTAHSNLYILAGHENSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMQGKSFKSDEVTQEISDETRVFRLLGSDRVVVLESRPTENPTAHSNLYILAGHENSY
500 510 520 530 540 550
>>NP_001257354 (OMIM: 604921) mitogen-activated protein (873 aa)
initn: 3874 init1: 1620 opt: 1935 Z-score: 795.9 bits: 158.3 E(85289): 1.4e-37
Smith-Waterman score: 3954; 67.5% identity (83.6% similar) in 879 aa overlap (5-846:1-873)
10 20 30 40 50 60
pF1KB8 MEAPLRPAADILRRNPQQDYELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFS
. :. :. :::::.:.::.::.::::::::::::::.::::::.:.::::::.::.
NP_001 MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFA
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 LIQQEIFMVKECKHCNIVAYFGSYLSREKLWICMEYCGGGSLQDIYHVTGPLSELQIAYV
..::::.:.:.::: :::::::::: :.:::::::.::::::::::::::::::::::::
NP_001 VVQQEIIMMKDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 CRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPY
::::::: :::.:::::::::::::::::.: ::::::::.:.::::::::::::::::
NP_001 SRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPY
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB8 WMAPEVAAVEKNGGYNQLCDIWAVGITAIELGELQPPMFDLHPMRALFLMSKSNFQPPKL
::::::::::..::::::::.::::::::::.::::::::::::::::::.:::::::::
NP_001 WMAPEVAAVERKGGYNQLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB8 KDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFVAQPGLSRALAVELLDKVNNPDNH
::: :::..::.:::.:::::::::::::.:: : ::.: :.:.::.:::::::::: :
NP_001 KDKMKWSNSFHHFVKMALTKNPKKRPTAEKLLQHPFVTQH-LTRSLAIELLDKVNNPD-H
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB8 AHYTEADDDDFEPHAIIRHTIRSTNRNARAERTASEINFDKLQFEPPLRKETEARDEMGL
. : . :::: :: . . : :.::.::.: :.: :::.: ...:.:::::::: . :. :
NP_001 STYHDFDDDDPEPLVAVPHRIHSTSRNVREEKTRSEITFGQVKFDPPLRKETEPHHELDL
300 310 320 330 340 350
370 380 390
pF1KB8 SSDPNFMLQWNPFVDGAN-----------------------------TGKSTSKRAIPPP
. . . : . :. ::: . .:: : ::::
NP_001 QLEYGQGHQGGYFL-GANKSLLKSVEEELHQRGHVAHLEDDEGDDDESKHSTLKAKIPPP
360 370 380 390 400 410
400 410 420 430 440
pF1KB8 LPPKPRISSYPEDNFPDE-EKASTIKHCPDSESRA-PQILRRQSSPSCGPVAETSSIGNG
:::::. :.. : :. .:::.:: : : : :. . . : : . ..:::
NP_001 LPPKPKSIFIPQEMHSTEDENQGTIKRCPMSGSPAKPSQVPPRPPPPRLPPHKPVALGNG
420 430 440 450 460 470
450 460 470 480 490 500
pF1KB8 DGISKLMSENTEGSAQAPQLPR-----KKDKRDFPKPAINGLPPTPKVLMGACFSKVFDG
. .: .: . : . : .:.:.: ::: ::::::::: :::::::::.:
NP_001 MSSFQLNGERDGSLCQQQNEHRGTNLSRKEKKDVPKPISNGLPPTPKVHMGACFSKVFNG
480 490 500 510 520 530
510 520 530 540 550 560
pF1KB8 CPLKINCATSWIHPDTKDQYIIFGTEDGIYTLNLNELHEATMEQLFPRKCTWLYVINNTL
:::::.::.:::.:::.:::.:::.:.::::::::::::..:::::::.::::::.:: :
NP_001 CPLKIHCASSWINPDTRDQYLIFGAEEGIYTLNLNELHETSMEQLFPRRCTWLYVMNNCL
540 550 560 570 580 590
570 580 590 600 610 620
pF1KB8 MSLSEGKTFQLYSHNLIALFEHAKK-PGLAAHIQTHRFPDRILPRKFALTTKIPDTKGCH
.:.: ::. ::::::: .::..:.. : . : .:..:::::::::....:::.:: :.
NP_001 LSIS-GKASQLYSHNLPGLFDYARQMQKLPVAIPAHKLPDRILPRKFSVSAKIPETKWCQ
600 610 620 630 640 650
630 640 650 660 670 680
pF1KB8 KCCIVRNPYTGHKYLCGALQSGIVLLQWYEPMQKFMLIKHFDFPLPSPLNVFEMLVIPEQ
:::.::::::::::::::::..::::.: :::::::::::.:::.: :: .:::::.:::
NP_001 KCCVVRNPYTGHKYLCGALQTSIVLLEWVEPMQKFMLIKHIDFPIPCPLRMFEMLVVPEQ
660 670 680 690 700 710
690 700 710 720 730 740
pF1KB8 EYPMVCVAISKGTESNQVVQFETINLNSASSWFTEIGAGSQQLDSIHVTQLERDTVLVCL
:::.:::..:.: . ::::.:::.: ::.:::::: . . : . :::::::::.::::
NP_001 EYPLVCVGVSRGRDFNQVVRFETVNPNSTSSWFTE--SDTPQTNVTHVTQLERDTILVCL
720 730 740 750 760 770
750 760 770 780 790 800
pF1KB8 DKFVKIVNLQGKLKSSKKLASELSFDFRIESVVCLQDSVLAFWKHGMQGKSFKSDEVTQE
: .:::::::.::::.::.:::.:::.:::.:::::::::::::::::.::.:.:::::
NP_001 DCCIKIVNLQGRLKSSRKLSSELTFDFQIESIVCLQDSVLAFWKHGMQGRSFRSNEVTQE
780 790 800 810 820 830
810 820 830 840
pF1KB8 ISDETRVFRLLGSDRVVVLESRPTENPTAHSNLYILAGHENSY
::: ::.:::::::::::::::::.::::.:::::::::::::
NP_001 ISDSTRIFRLLGSDRVVVLESRPTDNPTANSNLYILAGHENSY
840 850 860 870
>>NP_003609 (OMIM: 604921) mitogen-activated protein kin (894 aa)
initn: 3870 init1: 1620 opt: 1902 Z-score: 782.8 bits: 155.9 E(85289): 7.3e-37
Smith-Waterman score: 3799; 65.8% identity (81.7% similar) in 879 aa overlap (5-826:1-874)
10 20 30 40 50 60
pF1KB8 MEAPLRPAADILRRNPQQDYELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFS
. :. :. :::::.:.::.::.::::::::::::::.::::::.:.::::::.::.
NP_003 MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFA
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 LIQQEIFMVKECKHCNIVAYFGSYLSREKLWICMEYCGGGSLQDIYHVTGPLSELQIAYV
..::::.:.:.::: :::::::::: :.:::::::.::::::::::::::::::::::::
NP_003 VVQQEIIMMKDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 CRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPY
::::::: :::.:::::::::::::::::.: ::::::::.:.::::::::::::::::
NP_003 SRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPY
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB8 WMAPEVAAVEKNGGYNQLCDIWAVGITAIELGELQPPMFDLHPMRALFLMSKSNFQPPKL
::::::::::..::::::::.::::::::::.::::::::::::::::::.:::::::::
NP_003 WMAPEVAAVERKGGYNQLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB8 KDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFVAQPGLSRALAVELLDKVNNPDNH
::: :::..::.:::.:::::::::::::.:: : ::.: :.:.::.:::::::::: :
NP_003 KDKMKWSNSFHHFVKMALTKNPKKRPTAEKLLQHPFVTQH-LTRSLAIELLDKVNNPD-H
240 250 260 270 280 290
310 320 330 340 350
pF1KB8 AHYTEADDDDFEPHAIIRHTIRSTNRNARAERTASEINFDKLQFEPPLRKETEARDEM--
. : . :::: :: . . : :.::.::.: :.: :::.: ...:.:::::::: . :.
NP_003 STYHDFDDDDPEPLVAVPHRIHSTSRNVREEKTRSEITFGQVKFDPPLRKETEPHHELPD
300 310 320 330 340 350
360 370
pF1KB8 --GL--SSDP-------NFMLQ-------WNPFVDGAN----------------------
:. ::. :. :: . . :::
NP_003 SDGFLDSSEEIYYTARSNLDLQLEYGQGHQGGYFLGANKSLLKSVEEELHQRGHVAHLED
360 370 380 390 400 410
380 390 400 410 420
pF1KB8 -------TGKSTSKRAIPPPLPPKPRISSYPEDNFPDE-EKASTIKHCPDSESRA-PQIL
. .:: : :::::::::. :.. : :. .:::.:: : : : :. .
NP_003 DEGDDDESKHSTLKAKIPPPLPPKPKSIFIPQEMHSTEDENQGTIKRCPMSGSPAKPSQV
420 430 440 450 460 470
430 440 450 460 470 480
pF1KB8 RRQSSPSCGPVAETSSIGNGDGISKLMSENTEGSAQAPQLPR-----KKDKRDFPKPAIN
. : : . ..::: . .: .: . : . : .:.:.: ::: :
NP_003 PPRPPPPRLPPHKPVALGNGMSSFQLNGERDGSLCQQQNEHRGTNLSRKEKKDVPKPISN
480 490 500 510 520 530
490 500 510 520 530 540
pF1KB8 GLPPTPKVLMGACFSKVFDGCPLKINCATSWIHPDTKDQYIIFGTEDGIYTLNLNELHEA
:::::::: :::::::::.::::::.::.:::.:::.:::.:::.:.::::::::::::.
NP_003 GLPPTPKVHMGACFSKVFNGCPLKIHCASSWINPDTRDQYLIFGAEEGIYTLNLNELHET
540 550 560 570 580 590
550 560 570 580 590 600
pF1KB8 TMEQLFPRKCTWLYVINNTLMSLSEGKTFQLYSHNLIALFEHAKK-PGLAAHIQTHRFPD
.:::::::.::::::.:: :.:.: ::. ::::::: .::..:.. : . : .:..::
NP_003 SMEQLFPRRCTWLYVMNNCLLSIS-GKASQLYSHNLPGLFDYARQMQKLPVAIPAHKLPD
600 610 620 630 640 650
610 620 630 640 650 660
pF1KB8 RILPRKFALTTKIPDTKGCHKCCIVRNPYTGHKYLCGALQSGIVLLQWYEPMQKFMLIKH
:::::::....:::.:: :.:::.::::::::::::::::..::::.: :::::::::::
NP_003 RILPRKFSVSAKIPETKWCQKCCVVRNPYTGHKYLCGALQTSIVLLEWVEPMQKFMLIKH
660 670 680 690 700 710
670 680 690 700 710 720
pF1KB8 FDFPLPSPLNVFEMLVIPEQEYPMVCVAISKGTESNQVVQFETINLNSASSWFTEIGAGS
.:::.: :: .:::::.::::::.:::..:.: . ::::.:::.: ::.:::::: . .
NP_003 IDFPIPCPLRMFEMLVVPEQEYPLVCVGVSRGRDFNQVVRFETVNPNSTSSWFTE--SDT
720 730 740 750 760 770
730 740 750 760 770 780
pF1KB8 QQLDSIHVTQLERDTVLVCLDKFVKIVNLQGKLKSSKKLASELSFDFRIESVVCLQDSVL
: . :::::::::.::::: .:::::::.::::.::.:::.:::.:::.::::::::
NP_003 PQTNVTHVTQLERDTILVCLDCCIKIVNLQGRLKSSRKLSSELTFDFQIESIVCLQDSVL
780 790 800 810 820 830
790 800 810 820 830 840
pF1KB8 AFWKHGMQGKSFKSDEVTQEISDETRVFRLLGSDRVVVLESRPTENPTAHSNLYILAGHE
:::::::::.::.:.:::::::: ::.::::::::::::::::
NP_003 AFWKHGMQGRSFRSNEVTQEISDSTRIFRLLGSDRVVVLESRPTDNPTANSNLYILAGHE
840 850 860 870 880 890
pF1KB8 NSY
NP_003 NSY
>>NP_001036065 (OMIM: 601983) mitogen-activated protein (821 aa)
initn: 2421 init1: 1446 opt: 1689 Z-score: 698.9 bits: 140.3 E(85289): 3.4e-32
Smith-Waterman score: 2551; 47.6% identity (74.6% similar) in 844 aa overlap (10-838:7-819)
10 20 30 40 50 60
pF1KB8 MEAPLRPAADILRRNPQQDYELVQRVGSGTYGDVYKARNVHTGELAAVKIIKLEPGDDFS
::. :.:.. :.:.::.:.::::.:.:::. .:.:.:.:..:.:: :: :
NP_001 MDVVDPDIFNRDPRDHYDLLQRLGGGTYGEVFKARDKVSGDLVALKMVKMEPDDDVS
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 LIQQEIFMVKECKHCNIVAYFGSYLSREKLWICMEYCGGGSLQDIYHVTGPLSELQIAYV
.:.::...: :.: ::::: :::: .:::::::.::.:::::::.::: ::::::.::
NP_001 TLQKEILILKTCRHANIVAYHGSYLWLQKLWICMEFCGAGSLQDIYQVTGSLSELQISYV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 CRETLQGLAYLHTKGKMHRDIKGANILLTDHGDVKLADFGVAAKITATIAKRKSFIGTPY
:::.::::::::.. :.::::::::::..: :.:.:::::..:.: ::.:.: :::::::
NP_001 CREVLQGLAYLHSQKKIHRDIKGANILINDAGEVRLADFGISAQIGATLARRLSFIGTPY
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB8 WMAPEVAAVEKNGGYNQLCDIWAVGITAIELGELQPPMFDLHPMRALFLMSKSNFQPPKL
::::::::: .::::.:::::..:::::::.:::::.::.::.:.::::.::..:::.:
NP_001 WMAPEVAAVALKGGYNELCDIWSLGITAIELAELQPPLFDVHPLRVLFLMTKSGYQPPRL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB8 KDKTKWSSTFHNFVKIALTKNPKKRPTAERLLTHTFVAQPGLSRALAVELLDKVNNPDNH
:.: :::..::::.:..:::.:::::.: ..:.: .:.::::.:.: ..::::..:: .
NP_001 KEKGKWSAAFHNFIKVTLTKSPKKRPSATKMLSHQLVSQPGLNRGLILDLLDKLKNPGKG
240 250 260 270 280 290
310 320 330 340
pF1KB8 AHYTEADDDDFE-PHAIIRHTIRSTNRNAR-----AERTASEINFDKL---QFEPPLR--
. .:.. : : :: :. ::::.:.. :. ...: :: . .::
NP_001 PSIGDIEDEEPELPPAIPRR-IRSTHRSSSLGIPDADCCRRHMEFRKLRGMETRPPANTA
300 310 320 330 340 350
350 360 370 380 390 400
pF1KB8 KETEARDEMGLSSDPNFMLQWNPFVDGANTGKSTSKRAIPPPLPPKPRISSYPEDNFPDE
. :: ::.: .:. . : .. : . ::::::::.. : : :. :
NP_001 RLQPPRDLR--SSSPRKQLSESSDDDYDDVDIPTPAEDTPPPLPPKPKFRS-PSDEGPGS
360 370 380 390 400 410
410 420 430 440 450 460
pF1KB8 EKASTIKHCPDSESRAPQILRRQSSPSCGPVAETSSIGNGDGISK-LMSENTEGSAQAPQ
:. . .: .: : .: :: .. : . :. .. ..: : :
NP_001 MG--------DDGQLSPGVLVRCAS---GPPPNSPRPGPPPSTSSPHLTAHSEPSLWNP-
420 430 440 450 460
470 480 490 500 510 520
pF1KB8 LPRKKDKRDFPKPAINGLPPTP-KVLMGAC--FSKVFDGCPLKINCATSWIHPDTKDQYI
: .:.. :: . ::: :. .: . :.:.::::.:. ...: ::.::::..
NP_001 -P----SRELDKPPL--LPPKKEKMKRKGCALLVKLFNGCPLRIHSTAAWTHPSTKDQHL
470 480 490 500 510
530 540 550 560 570 580
pF1KB8 IFGTEDGIYTLNLNELHEATMEQLFPRKCTWLYVINNTLMSLSEGKTFQLYSHNLIALFE
..:.:.::. :: :. .:::.:.::: . ::.: :::.::::: ::: .::::....:.:
NP_001 LLGAEEGIFILNRND-QEATLEMLFPSRTTWVYSINNVLMSLS-GKTPHLYSHSILGLLE
520 530 540 550 560 570
590 600 610 620 630 640
pF1KB8 HAKKPGLAAHIQTHRFPDRILPRKFALTTKIPDTKGCHKCCIVRNPYTGHKYLCGALQSG
.: :.. .: : :.: :: ..::: :::::. ::.... .: .:::::...
NP_001 --RKETRAGNPIAHISPHRLLARKNMVSTKIQDTKGCRACCVAEGASSGGPFLCGALETS
580 590 600 610 620 630
650 660 670 680 690 700
pF1KB8 IVLLQWYEPMQKFMLIKHFDFPLPSPLNVFEMLVIPEQEYPMVCVAISKGTESNQVVQFE
.::::::.::.::.:... ::::.::.:: .:. : .: : ::...: : ...:. :.
NP_001 VVLLQWYQPMNKFLLVRQVLFPLPTPLSVFALLTGPGSELPAVCIGVSPGRPGKSVL-FH
640 650 660 670 680
710 720 730 740 750 760
pF1KB8 TINLNSASSWFTEIGAGSQQLDSIHVTQLERDTVLVCLDKFVKIVNLQGKLKSSKKLASE
:. ... : :. :. .... ..:::.:.: :.: .: ::.:. .:. . . . :
NP_001 TVRFGALSCWLGEM--STEHRGPVQVTQVEEDMVMVLMDGSVKLVTPEGSPVRGLR-TPE
690 700 710 720 730 740
770 780 790 800 810 820
pF1KB8 LSFDFRIESVVCLQDSVLAFWKHGMQGKSFKSDEVTQEISDETRVFRLLGSDRVVVLESR
. . .:.:. . .. ::::::.: .. ::.. ::. : : .:::::: : ::.:.:
NP_001 IPMTEAVEAVAMVGGQLQAFWKHGVQVWALGSDQLLQELRDPTLTFRLLGSPRPVVVETR
750 760 770 780 790 800
830 840
pF1KB8 PTENPTAHSNLYILAGHENSY
:...::: :::::
NP_001 PVDDPTAPSNLYIQE
810 820
846 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 08:18:30 2016 done: Sat Nov 5 08:18:32 2016
Total Scan time: 13.230 Total Display time: 0.290
Function used was FASTA [36.3.4 Apr, 2011]