FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8491, 903 aa 1>>>pF1KB8491 903 - 903 aa - 903 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 14.4176+/-0.000457; mu= -21.9696+/- 0.028 mean_var=557.0126+/-116.329, 0's: 0 Z-trim(123.6): 78 B-trim: 521 in 1/55 Lambda= 0.054343 statistics sampled from 43702 (43830) to 43702 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.792), E-opt: 0.2 (0.514), width: 16 Scan time: 18.390 The best scores are: opt bits E(85289) XP_016879621 (OMIM: 611425) PREDICTED: centrobin i ( 903) 5934 480.7 1.4e-134 NP_444279 (OMIM: 611425) centrobin isoform alpha [ ( 903) 5934 480.7 1.4e-134 XP_016879622 (OMIM: 611425) PREDICTED: centrobin i ( 903) 5934 480.7 1.4e-134 XP_016879620 (OMIM: 611425) PREDICTED: centrobin i ( 904) 5922 479.7 2.7e-134 XP_016879619 (OMIM: 611425) PREDICTED: centrobin i ( 904) 5922 479.7 2.7e-134 NP_001317053 (OMIM: 611425) centrobin isoform gamm ( 904) 5922 479.7 2.7e-134 XP_005256496 (OMIM: 611425) PREDICTED: centrobin i ( 871) 5614 455.6 4.8e-127 XP_005256495 (OMIM: 611425) PREDICTED: centrobin i ( 872) 5602 454.6 9.2e-127 XP_016879623 (OMIM: 611425) PREDICTED: centrobin i ( 893) 5500 446.7 2.4e-124 XP_016879617 (OMIM: 611425) PREDICTED: centrobin i ( 925) 5500 446.7 2.5e-124 XP_016879618 (OMIM: 611425) PREDICTED: centrobin i ( 925) 5500 446.7 2.5e-124 NP_001032221 (OMIM: 611425) centrobin isoform beta ( 925) 5500 446.7 2.5e-124 XP_016879626 (OMIM: 611425) PREDICTED: centrobin i ( 814) 5193 422.6 3.9e-117 XP_016879625 (OMIM: 611425) PREDICTED: centrobin i ( 815) 5181 421.6 7.5e-117 XP_016879624 (OMIM: 611425) PREDICTED: centrobin i ( 836) 4759 388.5 7e-107 XP_016879629 (OMIM: 611425) PREDICTED: centrobin i ( 717) 4661 380.8 1.3e-104 XP_016879628 (OMIM: 611425) PREDICTED: centrobin i ( 718) 4649 379.9 2.5e-104 XP_016879630 (OMIM: 611425) PREDICTED: centrobin i ( 708) 4273 350.4 1.8e-95 XP_016879627 (OMIM: 611425) PREDICTED: centrobin i ( 739) 4227 346.8 2.3e-94 XP_016879633 (OMIM: 611425) PREDICTED: centrobin i ( 615) 4091 336.1 3.2e-91 XP_016879631 (OMIM: 611425) PREDICTED: centrobin i ( 695) 4017 330.3 2e-89 XP_016879632 (OMIM: 611425) PREDICTED: centrobin i ( 637) 3657 302.1 5.8e-81 >>XP_016879621 (OMIM: 611425) PREDICTED: centrobin isofo (903 aa) initn: 5934 init1: 5934 opt: 5934 Z-score: 2537.2 bits: 480.7 E(85289): 1.4e-134 Smith-Waterman score: 5934; 99.9% identity (99.9% similar) in 903 aa overlap (1-903:1-903) 10 20 30 40 50 60 pF1KB8 MATSADSPSSPLGAEDLLSDSSEPPGLNQVSSEVTSQLYASLRLSRQAEATARAQLYLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MATSADSPSSPLGAEDLLSDSSEPPGLNQVSSEVTSQLYASLRLSRQAEATARAQLYLPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TSPPHEGLDGFAQELSRSLSVGLEKNLKKKDGSKHIFEMESVRGQLQTMLQTSRDTAYRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSPPHEGLDGFAQELSRSLSVGLEKNLKKKDGSKHIFEMESVRGQLQTMLQTSRDTAYRD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 PLIPGAGSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQALEELFPRYTSLRPGPPLNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLIPGAGSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQALEELFPRYTSLRPGPPLNP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PDFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PDFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 RVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESAR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 TARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 HRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 QLEEQRVELVERLQAMLQAHWDEANQLLSTTLPPPNPQAPPAGPSSPGPQEPEKEERRVW ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: XP_016 QLEEQRVELVERLQAMLQAHWDEANQLLSTTLPPPNPPAPPAGPSSPGPQEPEKEERRVW 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 TMPPMAVALKPVLQQSREARDELPGAPPVLCSSSSDLSLLLGPSFQSQHSFQPLEPKPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TMPPMAVALKPVLQQSREARDELPGAPPVLCSSSSDLSLLLGPSFQSQHSFQPLEPKPDL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 TSSTAGAFSALGAFHPDHRAERPFPEEDPGPDGEGLLKQGLPPAQLEGLKNFLHQLLETV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSSTAGAFSALGAFHPDHRAERPFPEEDPGPDGEGLLKQGLPPAQLEGLKNFLHQLLETV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 PQNNENPSVDLLPPKSGPLTVPSWEEAPQVPRIPPPVHKTKVPLAMASSLFRVPEPPSSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQNNENPSVDLLPPKSGPLTVPSWEEAPQVPRIPPPVHKTKVPLAMASSLFRVPEPPSSH 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB8 SQGSGPSSGSPERGGDGLTFPRQLMEVSQLLRLYQARGWGALPAEDLLLYLKRLEHSGTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQGSGPSSGSPERGGDGLTFPRQLMEVSQLLRLYQARGWGALPAEDLLLYLKRLEHSGTD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB8 GRGDNVPRRNTDSRLGEIPRKEIPSQAVPRRLATAPKTEKPPARKKSGHPAPSSMRSRGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRGDNVPRRNTDSRLGEIPRKEIPSQAVPRRLATAPKTEKPPARKKSGHPAPSSMRSRGG 850 860 870 880 890 900 pF1KB8 VWR ::: XP_016 VWR >>NP_444279 (OMIM: 611425) centrobin isoform alpha [Homo (903 aa) initn: 5934 init1: 5934 opt: 5934 Z-score: 2537.2 bits: 480.7 E(85289): 1.4e-134 Smith-Waterman score: 5934; 99.9% identity (99.9% similar) in 903 aa overlap (1-903:1-903) 10 20 30 40 50 60 pF1KB8 MATSADSPSSPLGAEDLLSDSSEPPGLNQVSSEVTSQLYASLRLSRQAEATARAQLYLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 MATSADSPSSPLGAEDLLSDSSEPPGLNQVSSEVTSQLYASLRLSRQAEATARAQLYLPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TSPPHEGLDGFAQELSRSLSVGLEKNLKKKDGSKHIFEMESVRGQLQTMLQTSRDTAYRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 TSPPHEGLDGFAQELSRSLSVGLEKNLKKKDGSKHIFEMESVRGQLQTMLQTSRDTAYRD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 PLIPGAGSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQALEELFPRYTSLRPGPPLNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 PLIPGAGSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQALEELFPRYTSLRPGPPLNP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PDFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 PDFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 RVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 RVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESAR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 LQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 TARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 TARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 HRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 HRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 QLEEQRVELVERLQAMLQAHWDEANQLLSTTLPPPNPQAPPAGPSSPGPQEPEKEERRVW ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: NP_444 QLEEQRVELVERLQAMLQAHWDEANQLLSTTLPPPNPPAPPAGPSSPGPQEPEKEERRVW 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 TMPPMAVALKPVLQQSREARDELPGAPPVLCSSSSDLSLLLGPSFQSQHSFQPLEPKPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 TMPPMAVALKPVLQQSREARDELPGAPPVLCSSSSDLSLLLGPSFQSQHSFQPLEPKPDL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 TSSTAGAFSALGAFHPDHRAERPFPEEDPGPDGEGLLKQGLPPAQLEGLKNFLHQLLETV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 TSSTAGAFSALGAFHPDHRAERPFPEEDPGPDGEGLLKQGLPPAQLEGLKNFLHQLLETV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 PQNNENPSVDLLPPKSGPLTVPSWEEAPQVPRIPPPVHKTKVPLAMASSLFRVPEPPSSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 PQNNENPSVDLLPPKSGPLTVPSWEEAPQVPRIPPPVHKTKVPLAMASSLFRVPEPPSSH 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB8 SQGSGPSSGSPERGGDGLTFPRQLMEVSQLLRLYQARGWGALPAEDLLLYLKRLEHSGTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 SQGSGPSSGSPERGGDGLTFPRQLMEVSQLLRLYQARGWGALPAEDLLLYLKRLEHSGTD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB8 GRGDNVPRRNTDSRLGEIPRKEIPSQAVPRRLATAPKTEKPPARKKSGHPAPSSMRSRGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_444 GRGDNVPRRNTDSRLGEIPRKEIPSQAVPRRLATAPKTEKPPARKKSGHPAPSSMRSRGG 850 860 870 880 890 900 pF1KB8 VWR ::: NP_444 VWR >>XP_016879622 (OMIM: 611425) PREDICTED: centrobin isofo (903 aa) initn: 5934 init1: 5934 opt: 5934 Z-score: 2537.2 bits: 480.7 E(85289): 1.4e-134 Smith-Waterman score: 5934; 99.9% identity (99.9% similar) in 903 aa overlap (1-903:1-903) 10 20 30 40 50 60 pF1KB8 MATSADSPSSPLGAEDLLSDSSEPPGLNQVSSEVTSQLYASLRLSRQAEATARAQLYLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MATSADSPSSPLGAEDLLSDSSEPPGLNQVSSEVTSQLYASLRLSRQAEATARAQLYLPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TSPPHEGLDGFAQELSRSLSVGLEKNLKKKDGSKHIFEMESVRGQLQTMLQTSRDTAYRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSPPHEGLDGFAQELSRSLSVGLEKNLKKKDGSKHIFEMESVRGQLQTMLQTSRDTAYRD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 PLIPGAGSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQALEELFPRYTSLRPGPPLNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLIPGAGSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQALEELFPRYTSLRPGPPLNP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PDFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PDFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 RVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESAR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 TARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 HRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 QLEEQRVELVERLQAMLQAHWDEANQLLSTTLPPPNPQAPPAGPSSPGPQEPEKEERRVW ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: XP_016 QLEEQRVELVERLQAMLQAHWDEANQLLSTTLPPPNPPAPPAGPSSPGPQEPEKEERRVW 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 TMPPMAVALKPVLQQSREARDELPGAPPVLCSSSSDLSLLLGPSFQSQHSFQPLEPKPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TMPPMAVALKPVLQQSREARDELPGAPPVLCSSSSDLSLLLGPSFQSQHSFQPLEPKPDL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 TSSTAGAFSALGAFHPDHRAERPFPEEDPGPDGEGLLKQGLPPAQLEGLKNFLHQLLETV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSSTAGAFSALGAFHPDHRAERPFPEEDPGPDGEGLLKQGLPPAQLEGLKNFLHQLLETV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 PQNNENPSVDLLPPKSGPLTVPSWEEAPQVPRIPPPVHKTKVPLAMASSLFRVPEPPSSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQNNENPSVDLLPPKSGPLTVPSWEEAPQVPRIPPPVHKTKVPLAMASSLFRVPEPPSSH 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB8 SQGSGPSSGSPERGGDGLTFPRQLMEVSQLLRLYQARGWGALPAEDLLLYLKRLEHSGTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQGSGPSSGSPERGGDGLTFPRQLMEVSQLLRLYQARGWGALPAEDLLLYLKRLEHSGTD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB8 GRGDNVPRRNTDSRLGEIPRKEIPSQAVPRRLATAPKTEKPPARKKSGHPAPSSMRSRGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRGDNVPRRNTDSRLGEIPRKEIPSQAVPRRLATAPKTEKPPARKKSGHPAPSSMRSRGG 850 860 870 880 890 900 pF1KB8 VWR ::: XP_016 VWR >>XP_016879620 (OMIM: 611425) PREDICTED: centrobin isofo (904 aa) initn: 5920 init1: 5484 opt: 5922 Z-score: 2532.1 bits: 479.7 E(85289): 2.7e-134 Smith-Waterman score: 5922; 99.8% identity (99.8% similar) in 904 aa overlap (1-903:1-904) 10 20 30 40 50 60 pF1KB8 MATSADSPSSPLGAEDLLSDSSEPPGLNQVSSEVTSQLYASLRLSRQAEATARAQLYLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MATSADSPSSPLGAEDLLSDSSEPPGLNQVSSEVTSQLYASLRLSRQAEATARAQLYLPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TSPPHEGLDGFAQELSRSLSVGLEKNLKKKDGSKHIFEMESVRGQLQTMLQTSRDTAYRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSPPHEGLDGFAQELSRSLSVGLEKNLKKKDGSKHIFEMESVRGQLQTMLQTSRDTAYRD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 PLIPGAGSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQALEELFPRYTSLRPGPPLNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLIPGAGSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQALEELFPRYTSLRPGPPLNP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PDFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PDFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 RVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESAR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 TARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 HRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 QLEEQRVELVERLQAMLQAHWDEANQLLSTTLPPPNPQAPPAGPSSPGPQEPEKEERRVW ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: XP_016 QLEEQRVELVERLQAMLQAHWDEANQLLSTTLPPPNPPAPPAGPSSPGPQEPEKEERRVW 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 TMPPMAVALKPVLQQSREARDELPGAPPVLCSSSSDLSLLLGPSFQSQHSFQPLEPKPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TMPPMAVALKPVLQQSREARDELPGAPPVLCSSSSDLSLLLGPSFQSQHSFQPLEPKPDL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 TSSTAGAFSALGAFHPDHRAERPFPEEDPGPDGEGLLKQGLPPAQLEGLKNFLHQLLETV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSSTAGAFSALGAFHPDHRAERPFPEEDPGPDGEGLLKQGLPPAQLEGLKNFLHQLLETV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 PQNNENPSVDLLPPKSGPLTVPSWEEAPQVPRIPPPVHKTKVPLAMASSLFRVPEPPSSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQNNENPSVDLLPPKSGPLTVPSWEEAPQVPRIPPPVHKTKVPLAMASSLFRVPEPPSSH 730 740 750 760 770 780 790 800 810 820 830 pF1KB8 SQGSGPSSGSPERGGDGLTFPRQLMEVSQLLRLYQARGWGALPAEDLLLYLKRLEHSG-T :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_016 SQGSGPSSGSPERGGDGLTFPRQLMEVSQLLRLYQARGWGALPAEDLLLYLKRLEHSGRT 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB8 DGRGDNVPRRNTDSRLGEIPRKEIPSQAVPRRLATAPKTEKPPARKKSGHPAPSSMRSRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGRGDNVPRRNTDSRLGEIPRKEIPSQAVPRRLATAPKTEKPPARKKSGHPAPSSMRSRG 850 860 870 880 890 900 900 pF1KB8 GVWR :::: XP_016 GVWR >>XP_016879619 (OMIM: 611425) PREDICTED: centrobin isofo (904 aa) initn: 5920 init1: 5484 opt: 5922 Z-score: 2532.1 bits: 479.7 E(85289): 2.7e-134 Smith-Waterman score: 5922; 99.8% identity (99.8% similar) in 904 aa overlap (1-903:1-904) 10 20 30 40 50 60 pF1KB8 MATSADSPSSPLGAEDLLSDSSEPPGLNQVSSEVTSQLYASLRLSRQAEATARAQLYLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MATSADSPSSPLGAEDLLSDSSEPPGLNQVSSEVTSQLYASLRLSRQAEATARAQLYLPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TSPPHEGLDGFAQELSRSLSVGLEKNLKKKDGSKHIFEMESVRGQLQTMLQTSRDTAYRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSPPHEGLDGFAQELSRSLSVGLEKNLKKKDGSKHIFEMESVRGQLQTMLQTSRDTAYRD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 PLIPGAGSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQALEELFPRYTSLRPGPPLNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLIPGAGSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQALEELFPRYTSLRPGPPLNP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PDFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PDFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 RVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESAR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 TARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 HRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 QLEEQRVELVERLQAMLQAHWDEANQLLSTTLPPPNPQAPPAGPSSPGPQEPEKEERRVW ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: XP_016 QLEEQRVELVERLQAMLQAHWDEANQLLSTTLPPPNPPAPPAGPSSPGPQEPEKEERRVW 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 TMPPMAVALKPVLQQSREARDELPGAPPVLCSSSSDLSLLLGPSFQSQHSFQPLEPKPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TMPPMAVALKPVLQQSREARDELPGAPPVLCSSSSDLSLLLGPSFQSQHSFQPLEPKPDL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 TSSTAGAFSALGAFHPDHRAERPFPEEDPGPDGEGLLKQGLPPAQLEGLKNFLHQLLETV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSSTAGAFSALGAFHPDHRAERPFPEEDPGPDGEGLLKQGLPPAQLEGLKNFLHQLLETV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 PQNNENPSVDLLPPKSGPLTVPSWEEAPQVPRIPPPVHKTKVPLAMASSLFRVPEPPSSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQNNENPSVDLLPPKSGPLTVPSWEEAPQVPRIPPPVHKTKVPLAMASSLFRVPEPPSSH 730 740 750 760 770 780 790 800 810 820 830 pF1KB8 SQGSGPSSGSPERGGDGLTFPRQLMEVSQLLRLYQARGWGALPAEDLLLYLKRLEHSG-T :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_016 SQGSGPSSGSPERGGDGLTFPRQLMEVSQLLRLYQARGWGALPAEDLLLYLKRLEHSGRT 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB8 DGRGDNVPRRNTDSRLGEIPRKEIPSQAVPRRLATAPKTEKPPARKKSGHPAPSSMRSRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DGRGDNVPRRNTDSRLGEIPRKEIPSQAVPRRLATAPKTEKPPARKKSGHPAPSSMRSRG 850 860 870 880 890 900 900 pF1KB8 GVWR :::: XP_016 GVWR >>NP_001317053 (OMIM: 611425) centrobin isoform gamma [H (904 aa) initn: 5920 init1: 5484 opt: 5922 Z-score: 2532.1 bits: 479.7 E(85289): 2.7e-134 Smith-Waterman score: 5922; 99.8% identity (99.8% similar) in 904 aa overlap (1-903:1-904) 10 20 30 40 50 60 pF1KB8 MATSADSPSSPLGAEDLLSDSSEPPGLNQVSSEVTSQLYASLRLSRQAEATARAQLYLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MATSADSPSSPLGAEDLLSDSSEPPGLNQVSSEVTSQLYASLRLSRQAEATARAQLYLPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TSPPHEGLDGFAQELSRSLSVGLEKNLKKKDGSKHIFEMESVRGQLQTMLQTSRDTAYRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSPPHEGLDGFAQELSRSLSVGLEKNLKKKDGSKHIFEMESVRGQLQTMLQTSRDTAYRD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 PLIPGAGSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQALEELFPRYTSLRPGPPLNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PLIPGAGSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQALEELFPRYTSLRPGPPLNP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PDFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PDFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 RVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESAR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 TARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 HRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 QLEEQRVELVERLQAMLQAHWDEANQLLSTTLPPPNPQAPPAGPSSPGPQEPEKEERRVW ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: NP_001 QLEEQRVELVERLQAMLQAHWDEANQLLSTTLPPPNPPAPPAGPSSPGPQEPEKEERRVW 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 TMPPMAVALKPVLQQSREARDELPGAPPVLCSSSSDLSLLLGPSFQSQHSFQPLEPKPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TMPPMAVALKPVLQQSREARDELPGAPPVLCSSSSDLSLLLGPSFQSQHSFQPLEPKPDL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 TSSTAGAFSALGAFHPDHRAERPFPEEDPGPDGEGLLKQGLPPAQLEGLKNFLHQLLETV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSSTAGAFSALGAFHPDHRAERPFPEEDPGPDGEGLLKQGLPPAQLEGLKNFLHQLLETV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 PQNNENPSVDLLPPKSGPLTVPSWEEAPQVPRIPPPVHKTKVPLAMASSLFRVPEPPSSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQNNENPSVDLLPPKSGPLTVPSWEEAPQVPRIPPPVHKTKVPLAMASSLFRVPEPPSSH 730 740 750 760 770 780 790 800 810 820 830 pF1KB8 SQGSGPSSGSPERGGDGLTFPRQLMEVSQLLRLYQARGWGALPAEDLLLYLKRLEHSG-T :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : NP_001 SQGSGPSSGSPERGGDGLTFPRQLMEVSQLLRLYQARGWGALPAEDLLLYLKRLEHSGRT 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB8 DGRGDNVPRRNTDSRLGEIPRKEIPSQAVPRRLATAPKTEKPPARKKSGHPAPSSMRSRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DGRGDNVPRRNTDSRLGEIPRKEIPSQAVPRRLATAPKTEKPPARKKSGHPAPSSMRSRG 850 860 870 880 890 900 900 pF1KB8 GVWR :::: NP_001 GVWR >>XP_005256496 (OMIM: 611425) PREDICTED: centrobin isofo (871 aa) initn: 5698 init1: 5611 opt: 5614 Z-score: 2401.8 bits: 455.6 E(85289): 4.8e-127 Smith-Waterman score: 5614; 98.5% identity (98.7% similar) in 870 aa overlap (1-870:1-870) 10 20 30 40 50 60 pF1KB8 MATSADSPSSPLGAEDLLSDSSEPPGLNQVSSEVTSQLYASLRLSRQAEATARAQLYLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MATSADSPSSPLGAEDLLSDSSEPPGLNQVSSEVTSQLYASLRLSRQAEATARAQLYLPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TSPPHEGLDGFAQELSRSLSVGLEKNLKKKDGSKHIFEMESVRGQLQTMLQTSRDTAYRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TSPPHEGLDGFAQELSRSLSVGLEKNLKKKDGSKHIFEMESVRGQLQTMLQTSRDTAYRD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 PLIPGAGSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQALEELFPRYTSLRPGPPLNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLIPGAGSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQALEELFPRYTSLRPGPPLNP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PDFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PDFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 RVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESAR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 TARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 HRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 QLEEQRVELVERLQAMLQAHWDEANQLLSTTLPPPNPQAPPAGPSSPGPQEPEKEERRVW ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: XP_005 QLEEQRVELVERLQAMLQAHWDEANQLLSTTLPPPNPPAPPAGPSSPGPQEPEKEERRVW 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 TMPPMAVALKPVLQQSREARDELPGAPPVLCSSSSDLSLLLGPSFQSQHSFQPLEPKPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TMPPMAVALKPVLQQSREARDELPGAPPVLCSSSSDLSLLLGPSFQSQHSFQPLEPKPDL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 TSSTAGAFSALGAFHPDHRAERPFPEEDPGPDGEGLLKQGLPPAQLEGLKNFLHQLLETV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TSSTAGAFSALGAFHPDHRAERPFPEEDPGPDGEGLLKQGLPPAQLEGLKNFLHQLLETV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 PQNNENPSVDLLPPKSGPLTVPSWEEAPQVPRIPPPVHKTKVPLAMASSLFRVPEPPSSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQNNENPSVDLLPPKSGPLTVPSWEEAPQVPRIPPPVHKTKVPLAMASSLFRVPEPPSSH 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB8 SQGSGPSSGSPERGGDGLTFPRQLMEVSQLLRLYQARGWGALPAEDLLLYLKRLEHSGTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SQGSGPSSGSPERGGDGLTFPRQLMEVSQLLRLYQARGWGALPAEDLLLYLKRLEHSGTD 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB8 GRGDNVPRRNTDSRLGEIPRKEIPSQAVPRRLATAPKTEKPPARKKSGHPAPSSMRSRGG ::::::::::::::: .: : :. XP_005 GRGDNVPRRNTDSRLDSLPGCPSPPCYSPQD 850 860 870 >>XP_005256495 (OMIM: 611425) PREDICTED: centrobin isofo (872 aa) initn: 5597 init1: 5484 opt: 5602 Z-score: 2396.8 bits: 454.6 E(85289): 9.2e-127 Smith-Waterman score: 5602; 98.4% identity (98.6% similar) in 871 aa overlap (1-870:1-871) 10 20 30 40 50 60 pF1KB8 MATSADSPSSPLGAEDLLSDSSEPPGLNQVSSEVTSQLYASLRLSRQAEATARAQLYLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MATSADSPSSPLGAEDLLSDSSEPPGLNQVSSEVTSQLYASLRLSRQAEATARAQLYLPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TSPPHEGLDGFAQELSRSLSVGLEKNLKKKDGSKHIFEMESVRGQLQTMLQTSRDTAYRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TSPPHEGLDGFAQELSRSLSVGLEKNLKKKDGSKHIFEMESVRGQLQTMLQTSRDTAYRD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 PLIPGAGSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQALEELFPRYTSLRPGPPLNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PLIPGAGSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQALEELFPRYTSLRPGPPLNP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PDFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PDFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 RVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESAR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 TARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 HRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 QLEEQRVELVERLQAMLQAHWDEANQLLSTTLPPPNPQAPPAGPSSPGPQEPEKEERRVW ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: XP_005 QLEEQRVELVERLQAMLQAHWDEANQLLSTTLPPPNPPAPPAGPSSPGPQEPEKEERRVW 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 TMPPMAVALKPVLQQSREARDELPGAPPVLCSSSSDLSLLLGPSFQSQHSFQPLEPKPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TMPPMAVALKPVLQQSREARDELPGAPPVLCSSSSDLSLLLGPSFQSQHSFQPLEPKPDL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 TSSTAGAFSALGAFHPDHRAERPFPEEDPGPDGEGLLKQGLPPAQLEGLKNFLHQLLETV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TSSTAGAFSALGAFHPDHRAERPFPEEDPGPDGEGLLKQGLPPAQLEGLKNFLHQLLETV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 PQNNENPSVDLLPPKSGPLTVPSWEEAPQVPRIPPPVHKTKVPLAMASSLFRVPEPPSSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PQNNENPSVDLLPPKSGPLTVPSWEEAPQVPRIPPPVHKTKVPLAMASSLFRVPEPPSSH 730 740 750 760 770 780 790 800 810 820 830 pF1KB8 SQGSGPSSGSPERGGDGLTFPRQLMEVSQLLRLYQARGWGALPAEDLLLYLKRLEHSG-T :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_005 SQGSGPSSGSPERGGDGLTFPRQLMEVSQLLRLYQARGWGALPAEDLLLYLKRLEHSGRT 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB8 DGRGDNVPRRNTDSRLGEIPRKEIPSQAVPRRLATAPKTEKPPARKKSGHPAPSSMRSRG :::::::::::::::: .: : :. XP_005 DGRGDNVPRRNTDSRLDSLPGCPSPPCYSPQD 850 860 870 900 pF1KB8 GVWR >>XP_016879623 (OMIM: 611425) PREDICTED: centrobin isofo (893 aa) initn: 5610 init1: 5484 opt: 5500 Z-score: 2353.4 bits: 446.7 E(85289): 2.4e-124 Smith-Waterman score: 5560; 96.1% identity (96.3% similar) in 892 aa overlap (1-870:1-892) 10 20 30 40 50 60 pF1KB8 MATSADSPSSPLGAEDLLSDSSEPPGLNQVSSEVTSQLYASLRLSRQAEATARAQLYLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MATSADSPSSPLGAEDLLSDSSEPPGLNQVSSEVTSQLYASLRLSRQAEATARAQLYLPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TSPPHEGLDGFAQELSRSLSVGLEKNLKKKDGSKHIFEMESVRGQLQTMLQTSRDTAYRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSPPHEGLDGFAQELSRSLSVGLEKNLKKKDGSKHIFEMESVRGQLQTMLQTSRDTAYRD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 PLIPGAGSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQALEELFPRYTSLRPGPPLNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLIPGAGSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQALEELFPRYTSLRPGPPLNP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PDFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PDFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 RVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESAR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 TARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 HRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 QLEEQRVELVERLQAMLQAHWDEANQLLSTTLPPPNPQAPPAGPSSPGPQEPEKEERRVW ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: XP_016 QLEEQRVELVERLQAMLQAHWDEANQLLSTTLPPPNPPAPPAGPSSPGPQEPEKEERRVW 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 TMPPMAVALKPVLQQSREARDELPGAPPVLCSSSSDLSLLLGPSFQSQHSFQPLEPKPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TMPPMAVALKPVLQQSREARDELPGAPPVLCSSSSDLSLLLGPSFQSQHSFQPLEPKPDL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 TSSTAGAFSALGAFHPDHRAERPFPEEDPGPDGEGLLKQGLPPAQLEGLKNFLHQLLETV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSSTAGAFSALGAFHPDHRAERPFPEEDPGPDGEGLLKQGLPPAQLEGLKNFLHQLLETV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 PQNNENPSVDLLPPKSGPLTVPSWEEAPQVPRIPPPVHKTKVPLAMASSLFRVPEPPSSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQNNENPSVDLLPPKSGPLTVPSWEEAPQVPRIPPPVHKTKVPLAMASSLFRVPEPPSSH 730 740 750 760 770 780 790 800 810 820 830 pF1KB8 SQGSGPSSGSPERGGDGLTFPRQLMEVSQLLRLYQARGWGALPAEDLLLYLKRLEHSG-- :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQGSGPSSGSPERGGDGLTFPRQLMEVSQLLRLYQARGWGALPAEDLLLYLKRLEHSGYK 790 800 810 820 830 840 840 850 860 870 pF1KB8 --------------------TDGRGDNVPRRNTDSRLGEIPRKEIPSQAVPRRLATAPKT ::::::::::::::::: .: : :. XP_016 PGRKEEGFSGWKLDYGEWSGTDGRGDNVPRRNTDSRLDSLPGCPSPPCYSPQD 850 860 870 880 890 880 890 900 pF1KB8 EKPPARKKSGHPAPSSMRSRGGVWR >>XP_016879617 (OMIM: 611425) PREDICTED: centrobin isofo (925 aa) initn: 5484 init1: 5484 opt: 5500 Z-score: 2353.2 bits: 446.7 E(85289): 2.5e-124 Smith-Waterman score: 5880; 97.5% identity (97.5% similar) in 925 aa overlap (1-903:1-925) 10 20 30 40 50 60 pF1KB8 MATSADSPSSPLGAEDLLSDSSEPPGLNQVSSEVTSQLYASLRLSRQAEATARAQLYLPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MATSADSPSSPLGAEDLLSDSSEPPGLNQVSSEVTSQLYASLRLSRQAEATARAQLYLPS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TSPPHEGLDGFAQELSRSLSVGLEKNLKKKDGSKHIFEMESVRGQLQTMLQTSRDTAYRD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSPPHEGLDGFAQELSRSLSVGLEKNLKKKDGSKHIFEMESVRGQLQTMLQTSRDTAYRD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 PLIPGAGSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQALEELFPRYTSLRPGPPLNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PLIPGAGSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQALEELFPRYTSLRPGPPLNP 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PDFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PDFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 RVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESAR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQ 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELD 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 TARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 HRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 QLEEQRVELVERLQAMLQAHWDEANQLLSTTLPPPNPQAPPAGPSSPGPQEPEKEERRVW ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: XP_016 QLEEQRVELVERLQAMLQAHWDEANQLLSTTLPPPNPPAPPAGPSSPGPQEPEKEERRVW 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 TMPPMAVALKPVLQQSREARDELPGAPPVLCSSSSDLSLLLGPSFQSQHSFQPLEPKPDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TMPPMAVALKPVLQQSREARDELPGAPPVLCSSSSDLSLLLGPSFQSQHSFQPLEPKPDL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 TSSTAGAFSALGAFHPDHRAERPFPEEDPGPDGEGLLKQGLPPAQLEGLKNFLHQLLETV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TSSTAGAFSALGAFHPDHRAERPFPEEDPGPDGEGLLKQGLPPAQLEGLKNFLHQLLETV 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 PQNNENPSVDLLPPKSGPLTVPSWEEAPQVPRIPPPVHKTKVPLAMASSLFRVPEPPSSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PQNNENPSVDLLPPKSGPLTVPSWEEAPQVPRIPPPVHKTKVPLAMASSLFRVPEPPSSH 730 740 750 760 770 780 790 800 810 820 830 pF1KB8 SQGSGPSSGSPERGGDGLTFPRQLMEVSQLLRLYQARGWGALPAEDLLLYLKRLEHSG-- :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQGSGPSSGSPERGGDGLTFPRQLMEVSQLLRLYQARGWGALPAEDLLLYLKRLEHSGYK 790 800 810 820 830 840 840 850 860 870 pF1KB8 --------------------TDGRGDNVPRRNTDSRLGEIPRKEIPSQAVPRRLATAPKT :::::::::::::::::::::::::::::::::::::::: XP_016 PGRKEEGFSGWKLDYGEWSGTDGRGDNVPRRNTDSRLGEIPRKEIPSQAVPRRLATAPKT 850 860 870 880 890 900 880 890 900 pF1KB8 EKPPARKKSGHPAPSSMRSRGGVWR ::::::::::::::::::::::::: XP_016 EKPPARKKSGHPAPSSMRSRGGVWR 910 920 903 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 15:40:52 2016 done: Sat Nov 5 15:40:54 2016 Total Scan time: 18.390 Total Display time: 0.280 Function used was FASTA [36.3.4 Apr, 2011]