FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8496, 861 aa
  1>>>pF1KB8496 861 - 861 aa - 861 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.2587+/-0.00104; mu= 6.6098+/- 0.062
 mean_var=133.0241+/-26.531, 0's: 0 Z-trim(107.7): 30  B-trim: 3 in 1/51
 Lambda= 0.111201
 statistics sampled from 9726 (9740) to 9726 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.653), E-opt: 0.2 (0.299), width:  16
 Scan time:  4.630

The best scores are:                                      opt bits E(32554)
CCDS566.1 ORC1 gene_id:4998|Hs108|chr1             ( 861) 5663 920.6       0
CCDS11365.1 CDC6 gene_id:990|Hs108|chr17           ( 560)  516 94.8 4.6e-19


>>CCDS566.1 ORC1 gene_id:4998|Hs108|chr1                  (861 aa)
 initn: 5663 init1: 5663 opt: 5663  Z-score: 4915.3  bits: 920.6 E(32554):    0
Smith-Waterman score: 5663; 100.0% identity (100.0% similar) in 861 aa overlap (1-861:1-861)

               10        20        30        40        50        60
pF1KB8 MAHYPTRLKTRKTYSWVGRPLLDRKLHYQTYREMCVKTEGCSTEIHIQIGQFVLIEGDDD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MAHYPTRLKTRKTYSWVGRPLLDRKLHYQTYREMCVKTEGCSTEIHIQIGQFVLIEGDDD
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 ENPYVAKLLELFEDDSDPPPKKRARVQWFVRFCEVPACKRHLLGRKPGAQEIFWYDYPAC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 ENPYVAKLLELFEDDSDPPPKKRARVQWFVRFCEVPACKRHLLGRKPGAQEIFWYDYPAC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 DSNINAETIIGLVRVIPLAPKDVVPTNLKNEKTLFVKLSWNEKKFRPLSSELFAELNKPQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 DSNINAETIIGLVRVIPLAPKDVVPTNLKNEKTLFVKLSWNEKKFRPLSSELFAELNKPQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 ESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLTPRARKRLELG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 ESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLTPRARKRLELG
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 NLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPALKAPEKTRETG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 NLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPALKAPEKTRETG
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 LSYTEDDKKASPEHRIILRTRIAASKTIDIREERTLTPISGGQRSSVVPSVILKPENIKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LSYTEDDKKASPEHRIILRTRIAASKTIDIREERTLTPISGGQRSSVVPSVILKPENIKK
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 RDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPAAEISDSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 RDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPAAEISDSS
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 SDEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 SDEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSLA
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 AQEPASVLEEARLRLHVSAVPESLPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 AQEPASVLEEARLRLHVSAVPESLPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGK
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB8 TATVHEVIRCLQQAAQANDVPPFQYIEVNGMKLTEPHQVYVQILQKLTGQKATANHAAEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 TATVHEVIRCLQQAAQANDVPPFQYIEVNGMKLTEPHQVYVQILQKLTGQKATANHAAEL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB8 LAKQFCTRGSPQETTVLLVDELDLLWTHKQDIMYNLFDWPTHKEARLVVLAIANTMDLPE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LAKQFCTRGSPQETTVLLVDELDLLWTHKQDIMYNLFDWPTHKEARLVVLAIANTMDLPE
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB8 RIMMNRVSSRLGLTRMCFQPYTYSQLQQILRSRLKHLKAFEDDAIQLVARKVAALSGDAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 RIMMNRVSSRLGLTRMCFQPYTYSQLQQILRSRLKHLKAFEDDAIQLVARKVAALSGDAR
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB8 RCLDICRRATEICEFSQQKPDSPGLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLRA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 RCLDICRRATEICEFSQQKPDSPGLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLRA
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB8 ILAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSHLGSCRLLLVEPSRND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 ILAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSHLGSCRLLLVEPSRND
              790       800       810       820       830       840

              850       860 
pF1KB8 LLLRVRLNVSQDDVLYALKDE
       :::::::::::::::::::::
CCDS56 LLLRVRLNVSQDDVLYALKDE
              850       860 

>>CCDS11365.1 CDC6 gene_id:990|Hs108|chr17                (560 aa)
 initn: 353 init1: 167 opt: 516  Z-score: 455.8  bits: 94.8 E(32554): 4.6e-19
Smith-Waterman score: 604; 28.3% identity (62.3% similar) in 467 aa overlap (422-861:99-548)

             400       410       420       430       440       450 
pF1KB8 RQQLRFLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLRSSLKSSL
                                     :.. .   :  :.  .. . .. ::...: 
CCDS11 HLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKILSSVRKSQ
       70        80        90       100       110       120        

             460       470       480       490       500       510 
pF1KB8 HTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQEPASVLEEARLRLHVSAVPESLPCREQEF
       .  :.  ..    .   :    .:   :  :: ..  ..:.: :. .:::. :: ::.:.
CCDS11 EITTNSEQRCPLKKESAC----VR---LFKQE-GTCYQQAKLVLN-TAVPDRLPAREREM
      130       140              150        160        170         

             520       530       540       550       560       570 
pF1KB8 QDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQANDVPPFQYIEVNGM
       . : ::.. ..  . .: .:.::.::::::: . .... :..     ..  :. : .: :
CCDS11 DVIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKK-----ELKGFKTIMLNCM
     180       190       200       210       220            230    

             580       590       600          610       620        
pF1KB8 KLTEPHQVYVQILQKLTGQKATANHAAEL---LAKQFCTRGSPQETTVLLVDELDLLWTH
       .:   . :.  : :..  ....   . ..   : :.. .. .:.   ::..::.: : ..
CCDS11 SLRTAQAVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPM--IVLVLDEMDQLDSK
          240       250       260       270         280       290  

      630       640       650       660       670         680      
pF1KB8 KQDIMYNLFDWPTHKEARLVVLAIANTMDLPERIMMNRVSSRLGLTR--MCFQPYTYSQL
        ::..:.::.::  ....::...::::.:: .::.  :...:       . : ::: .:.
CCDS11 GQDVLYTLFEWPWLSNSHLVLIGIANTLDLTDRIL-PRLQAREKCKPQLLNFPPYTRNQI
            300       310       320        330       340       350 

        690          700       710       720       730             
pF1KB8 QQILRSRLKHL---KAFEDDAIQLVARKVAALSGDARRCLDICRRATEICEF---SQ---
         ::..::...   ..... :.:. ::::.:.:::.:. ::.:::: :: :    ::   
CCDS11 VTILQDRLNQVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRRAIEIVESDVKSQTIL
             360       370       380       390       400       410 

             740             750       760       770        780    
pF1KB8 ------QKPDSP------GLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLR-AILAE
             ..:. :      ::. :.. .  ::    .    . ..:  :.:..:  ...  
CCDS11 KPLSECKSPSEPLIPKRVGLIHISQVISEVDGNRMTLSQEGAQDSFPLQQKILVCSLMLL
             420       430       440       450       460       470 

          790       800       810       820       830       840    
pF1KB8 FRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSHLGSCRLLLVEPSRNDLLLR
       .:.  ..:.:. ..:  .  .:: . .    .:: ... . : .  .: .. ...  : .
CCDS11 IRQLKIKEVTLGKLYEAYSKVCRKQQVAAVDQSECLSLSGLLEARGILGLKRNKETRLTK
             480       490       500       510       520       530 

          850       860             
pF1KB8 VRLNVSQDDVLYALKDE            
       : ... . .. .::::.            
CCDS11 VFFKIEEKEIEHALKDKALIGNILATGLP
             540       550       560




861 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 16:29:38 2016 done: Sat Nov  5 16:29:39 2016
 Total Scan time:  4.630 Total Display time:  0.050

Function used was FASTA [36.3.4 Apr, 2011]