FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8496, 861 aa 1>>>pF1KB8496 861 - 861 aa - 861 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.0811+/-0.000448; mu= 7.8972+/- 0.028 mean_var=152.7080+/-32.115, 0's: 0 Z-trim(114.8): 30 B-trim: 1283 in 2/52 Lambda= 0.103787 statistics sampled from 24853 (24882) to 24853 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.651), E-opt: 0.2 (0.292), width: 16 Scan time: 14.400 The best scores are: opt bits E(85289) NP_001177747 (OMIM: 224690,601902) origin recognit ( 861) 5663 860.7 0 NP_004144 (OMIM: 224690,601902) origin recognition ( 861) 5663 860.7 0 NP_001177748 (OMIM: 224690,601902) origin recognit ( 856) 5611 852.9 0 XP_016856878 (OMIM: 224690,601902) PREDICTED: orig ( 615) 3973 607.6 5.8e-173 XP_016856877 (OMIM: 224690,601902) PREDICTED: orig ( 825) 3865 591.5 5.4e-168 XP_011539829 (OMIM: 224690,601902) PREDICTED: orig ( 501) 3251 499.4 1.7e-140 NP_001245 (OMIM: 602627,613805) cell division cont ( 560) 516 89.9 3.5e-17 XP_011523844 (OMIM: 602627,613805) PREDICTED: cell ( 600) 492 86.3 4.5e-16 XP_011523843 (OMIM: 602627,613805) PREDICTED: cell ( 600) 492 86.3 4.5e-16 >>NP_001177747 (OMIM: 224690,601902) origin recognition (861 aa) initn: 5663 init1: 5663 opt: 5663 Z-score: 4591.7 bits: 860.7 E(85289): 0 Smith-Waterman score: 5663; 100.0% identity (100.0% similar) in 861 aa overlap (1-861:1-861) 10 20 30 40 50 60 pF1KB8 MAHYPTRLKTRKTYSWVGRPLLDRKLHYQTYREMCVKTEGCSTEIHIQIGQFVLIEGDDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAHYPTRLKTRKTYSWVGRPLLDRKLHYQTYREMCVKTEGCSTEIHIQIGQFVLIEGDDD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ENPYVAKLLELFEDDSDPPPKKRARVQWFVRFCEVPACKRHLLGRKPGAQEIFWYDYPAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENPYVAKLLELFEDDSDPPPKKRARVQWFVRFCEVPACKRHLLGRKPGAQEIFWYDYPAC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 DSNINAETIIGLVRVIPLAPKDVVPTNLKNEKTLFVKLSWNEKKFRPLSSELFAELNKPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSNINAETIIGLVRVIPLAPKDVVPTNLKNEKTLFVKLSWNEKKFRPLSSELFAELNKPQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLTPRARKRLELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLTPRARKRLELG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPALKAPEKTRETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPALKAPEKTRETG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LSYTEDDKKASPEHRIILRTRIAASKTIDIREERTLTPISGGQRSSVVPSVILKPENIKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSYTEDDKKASPEHRIILRTRIAASKTIDIREERTLTPISGGQRSSVVPSVILKPENIKK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 RDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPAAEISDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPAAEISDSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 SDEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSLA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 AQEPASVLEEARLRLHVSAVPESLPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AQEPASVLEEARLRLHVSAVPESLPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 TATVHEVIRCLQQAAQANDVPPFQYIEVNGMKLTEPHQVYVQILQKLTGQKATANHAAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TATVHEVIRCLQQAAQANDVPPFQYIEVNGMKLTEPHQVYVQILQKLTGQKATANHAAEL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 LAKQFCTRGSPQETTVLLVDELDLLWTHKQDIMYNLFDWPTHKEARLVVLAIANTMDLPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAKQFCTRGSPQETTVLLVDELDLLWTHKQDIMYNLFDWPTHKEARLVVLAIANTMDLPE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 RIMMNRVSSRLGLTRMCFQPYTYSQLQQILRSRLKHLKAFEDDAIQLVARKVAALSGDAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIMMNRVSSRLGLTRMCFQPYTYSQLQQILRSRLKHLKAFEDDAIQLVARKVAALSGDAR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 RCLDICRRATEICEFSQQKPDSPGLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RCLDICRRATEICEFSQQKPDSPGLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLRA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB8 ILAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSHLGSCRLLLVEPSRND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSHLGSCRLLLVEPSRND 790 800 810 820 830 840 850 860 pF1KB8 LLLRVRLNVSQDDVLYALKDE ::::::::::::::::::::: NP_001 LLLRVRLNVSQDDVLYALKDE 850 860 >>NP_004144 (OMIM: 224690,601902) origin recognition com (861 aa) initn: 5663 init1: 5663 opt: 5663 Z-score: 4591.7 bits: 860.7 E(85289): 0 Smith-Waterman score: 5663; 100.0% identity (100.0% similar) in 861 aa overlap (1-861:1-861) 10 20 30 40 50 60 pF1KB8 MAHYPTRLKTRKTYSWVGRPLLDRKLHYQTYREMCVKTEGCSTEIHIQIGQFVLIEGDDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MAHYPTRLKTRKTYSWVGRPLLDRKLHYQTYREMCVKTEGCSTEIHIQIGQFVLIEGDDD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ENPYVAKLLELFEDDSDPPPKKRARVQWFVRFCEVPACKRHLLGRKPGAQEIFWYDYPAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ENPYVAKLLELFEDDSDPPPKKRARVQWFVRFCEVPACKRHLLGRKPGAQEIFWYDYPAC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 DSNINAETIIGLVRVIPLAPKDVVPTNLKNEKTLFVKLSWNEKKFRPLSSELFAELNKPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 DSNINAETIIGLVRVIPLAPKDVVPTNLKNEKTLFVKLSWNEKKFRPLSSELFAELNKPQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLTPRARKRLELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLTPRARKRLELG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPALKAPEKTRETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPALKAPEKTRETG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LSYTEDDKKASPEHRIILRTRIAASKTIDIREERTLTPISGGQRSSVVPSVILKPENIKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LSYTEDDKKASPEHRIILRTRIAASKTIDIREERTLTPISGGQRSSVVPSVILKPENIKK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 RDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPAAEISDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPAAEISDSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 SDEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SDEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSLA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 AQEPASVLEEARLRLHVSAVPESLPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AQEPASVLEEARLRLHVSAVPESLPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 TATVHEVIRCLQQAAQANDVPPFQYIEVNGMKLTEPHQVYVQILQKLTGQKATANHAAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 TATVHEVIRCLQQAAQANDVPPFQYIEVNGMKLTEPHQVYVQILQKLTGQKATANHAAEL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 LAKQFCTRGSPQETTVLLVDELDLLWTHKQDIMYNLFDWPTHKEARLVVLAIANTMDLPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 LAKQFCTRGSPQETTVLLVDELDLLWTHKQDIMYNLFDWPTHKEARLVVLAIANTMDLPE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 RIMMNRVSSRLGLTRMCFQPYTYSQLQQILRSRLKHLKAFEDDAIQLVARKVAALSGDAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RIMMNRVSSRLGLTRMCFQPYTYSQLQQILRSRLKHLKAFEDDAIQLVARKVAALSGDAR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 RCLDICRRATEICEFSQQKPDSPGLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 RCLDICRRATEICEFSQQKPDSPGLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLRA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB8 ILAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSHLGSCRLLLVEPSRND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 ILAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSHLGSCRLLLVEPSRND 790 800 810 820 830 840 850 860 pF1KB8 LLLRVRLNVSQDDVLYALKDE ::::::::::::::::::::: NP_004 LLLRVRLNVSQDDVLYALKDE 850 860 >>NP_001177748 (OMIM: 224690,601902) origin recognition (856 aa) initn: 3009 init1: 3009 opt: 5611 Z-score: 4549.6 bits: 852.9 E(85289): 0 Smith-Waterman score: 5611; 99.4% identity (99.4% similar) in 861 aa overlap (1-861:1-856) 10 20 30 40 50 60 pF1KB8 MAHYPTRLKTRKTYSWVGRPLLDRKLHYQTYREMCVKTEGCSTEIHIQIGQFVLIEGDDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAHYPTRLKTRKTYSWVGRPLLDRKLHYQTYREMCVKTEGCSTEIHIQIGQFVLIEGDDD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ENPYVAKLLELFEDDSDPPPKKRARVQWFVRFCEVPACKRHLLGRKPGAQEIFWYDYPAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENPYVAKLLELFEDDSDPPPKKRARVQWFVRFCEVPACKRHLLGRKPGAQEIFWYDYPAC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 DSNINAETIIGLVRVIPLAPKDVVPTNLKNEKTLFVKLSWNEKKFRPLSSELFAELNKPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSNINAETIIGLVRVIPLAPKDVVPTNLKNEKTLFVKLSWNEKKFRPLSSELFAELNKPQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLTPRARKRLELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLTPRARKRLELG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPALKAPEKTRETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPALKAPEKTRETG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LSYTEDDKKASPEHRIILRTRIAASKTIDIREERTLTPISGGQRSSVVPSVILKPENIKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LSYTEDDKKASPEHRIILRTRIAASKTIDIREERTLTPISGGQRSSVVPSVILKPENIKK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 RDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPAAEISDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPAAEISDSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 SDEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSLA :::::::::::::::::::::::::::::::::::: ::::::::::::::::::: NP_001 SDEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTK-----LKPRTPRCAAPQIRSRSLA 430 440 450 460 470 490 500 510 520 530 540 pF1KB8 AQEPASVLEEARLRLHVSAVPESLPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AQEPASVLEEARLRLHVSAVPESLPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGK 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB8 TATVHEVIRCLQQAAQANDVPPFQYIEVNGMKLTEPHQVYVQILQKLTGQKATANHAAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TATVHEVIRCLQQAAQANDVPPFQYIEVNGMKLTEPHQVYVQILQKLTGQKATANHAAEL 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB8 LAKQFCTRGSPQETTVLLVDELDLLWTHKQDIMYNLFDWPTHKEARLVVLAIANTMDLPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAKQFCTRGSPQETTVLLVDELDLLWTHKQDIMYNLFDWPTHKEARLVVLAIANTMDLPE 600 610 620 630 640 650 670 680 690 700 710 720 pF1KB8 RIMMNRVSSRLGLTRMCFQPYTYSQLQQILRSRLKHLKAFEDDAIQLVARKVAALSGDAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIMMNRVSSRLGLTRMCFQPYTYSQLQQILRSRLKHLKAFEDDAIQLVARKVAALSGDAR 660 670 680 690 700 710 730 740 750 760 770 780 pF1KB8 RCLDICRRATEICEFSQQKPDSPGLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RCLDICRRATEICEFSQQKPDSPGLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLRA 720 730 740 750 760 770 790 800 810 820 830 840 pF1KB8 ILAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSHLGSCRLLLVEPSRND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSHLGSCRLLLVEPSRND 780 790 800 810 820 830 850 860 pF1KB8 LLLRVRLNVSQDDVLYALKDE ::::::::::::::::::::: NP_001 LLLRVRLNVSQDDVLYALKDE 840 850 >>XP_016856878 (OMIM: 224690,601902) PREDICTED: origin r (615 aa) initn: 3973 init1: 3973 opt: 3973 Z-score: 3226.3 bits: 607.6 E(85289): 5.8e-173 Smith-Waterman score: 3973; 100.0% identity (100.0% similar) in 615 aa overlap (247-861:1-615) 220 230 240 250 260 270 pF1KB8 SASKSRQTPTHPLTPRARKRLELGNLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSK :::::::::::::::::::::::::::::: XP_016 MSQQTSCASLDSPGRIKRKVAFSEITSPSK 10 20 30 280 290 300 310 320 330 pF1KB8 RSQPDKLQTLSPALKAPEKTRETGLSYTEDDKKASPEHRIILRTRIAASKTIDIREERTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSQPDKLQTLSPALKAPEKTRETGLSYTEDDKKASPEHRIILRTRIAASKTIDIREERTL 40 50 60 70 80 90 340 350 360 370 380 390 pF1KB8 TPISGGQRSSVVPSVILKPENIKKRDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPISGGQRSSVVPSVILKPENIKKRDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLR 100 110 120 130 140 150 400 410 420 430 440 450 pF1KB8 FLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTK 160 170 180 190 200 210 460 470 480 490 500 510 pF1KB8 VPKKSLKPRTPRCAAPQIRSRSLAAQEPASVLEEARLRLHVSAVPESLPCREQEFQDIYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPKKSLKPRTPRCAAPQIRSRSLAAQEPASVLEEARLRLHVSAVPESLPCREQEFQDIYN 220 230 240 250 260 270 520 530 540 550 560 570 pF1KB8 FVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQANDVPPFQYIEVNGMKLTEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQANDVPPFQYIEVNGMKLTEP 280 290 300 310 320 330 580 590 600 610 620 630 pF1KB8 HQVYVQILQKLTGQKATANHAAELLAKQFCTRGSPQETTVLLVDELDLLWTHKQDIMYNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HQVYVQILQKLTGQKATANHAAELLAKQFCTRGSPQETTVLLVDELDLLWTHKQDIMYNL 340 350 360 370 380 390 640 650 660 670 680 690 pF1KB8 FDWPTHKEARLVVLAIANTMDLPERIMMNRVSSRLGLTRMCFQPYTYSQLQQILRSRLKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FDWPTHKEARLVVLAIANTMDLPERIMMNRVSSRLGLTRMCFQPYTYSQLQQILRSRLKH 400 410 420 430 440 450 700 710 720 730 740 750 pF1KB8 LKAFEDDAIQLVARKVAALSGDARRCLDICRRATEICEFSQQKPDSPGLVTIAHSMEAVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKAFEDDAIQLVARKVAALSGDARRCLDICRRATEICEFSQQKPDSPGLVTIAHSMEAVD 460 470 480 490 500 510 760 770 780 790 800 810 pF1KB8 EMFSSSYITAIKNSSVLEQSFLRAILAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EMFSSSYITAIKNSSVLEQSFLRAILAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTM 520 530 540 550 560 570 820 830 840 850 860 pF1KB8 SETMAVCSHLGSCRLLLVEPSRNDLLLRVRLNVSQDDVLYALKDE ::::::::::::::::::::::::::::::::::::::::::::: XP_016 SETMAVCSHLGSCRLLLVEPSRNDLLLRVRLNVSQDDVLYALKDE 580 590 600 610 >>XP_016856877 (OMIM: 224690,601902) PREDICTED: origin r (825 aa) initn: 3865 init1: 3865 opt: 3865 Z-score: 3137.0 bits: 591.5 E(85289): 5.4e-168 Smith-Waterman score: 5355; 95.8% identity (95.8% similar) in 861 aa overlap (1-861:1-825) 10 20 30 40 50 60 pF1KB8 MAHYPTRLKTRKTYSWVGRPLLDRKLHYQTYREMCVKTEGCSTEIHIQIGQFVLIEGDDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAHYPTRLKTRKTYSWVGRPLLDRKLHYQTYREMCVKTEGCSTEIHIQIGQFVLIEGDDD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ENPYVAKLLELFEDDSDPPPKKRARVQWFVRFCEVPACKRHLLGRKPGAQEIFWYDYPAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENPYVAKLLELFEDDSDPPPKKRARVQWFVRFCEVPACKRHLLGRKPGAQEIFWYDYPAC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 DSNINAETIIGLVRVIPLAPKDVVPTNLKNEKTLFVKLSWNEKKFRPLSSELFAELNKPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSNINAETIIGLVRVIPLAPKDVVPTNLKNEKTLFVKLSWNEKKFRPLSSELFAELNKPQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLTPRARKRLELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLTPRARKRLELG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPALKAPEKTRETG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPALKAPEKTRETG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 LSYTEDDKKASPEHRIILRTRIAASKTIDIREERTLTPISGGQRSSVVPSVILKPENIKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSYTEDDKKASPEHRIILRTRIAASKTIDIREERTLTPISGGQRSSVVPSVILKPENIKK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 RDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPAAEISDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPAAEISDSS 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 SDEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSLA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 AQEPASVLEEARLRLHVSAVPESLPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AQEPASVLEEARLRLHVSAVPESLPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGK 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 TATVHEVIRCLQQAAQANDVPPFQYIEVNGMKLTEPHQVYVQILQKLTGQKATANHAAEL ::::::::::::::::::::::::::::::::::::::::::::: XP_016 TATVHEVIRCLQQAAQANDVPPFQYIEVNGMKLTEPHQVYVQILQ--------------- 550 560 570 580 610 620 630 640 650 660 pF1KB8 LAKQFCTRGSPQETTVLLVDELDLLWTHKQDIMYNLFDWPTHKEARLVVLAIANTMDLPE ::::::::::::::::::::::::::::::::::::::: XP_016 ---------------------LDLLWTHKQDIMYNLFDWPTHKEARLVVLAIANTMDLPE 590 600 610 620 670 680 690 700 710 720 pF1KB8 RIMMNRVSSRLGLTRMCFQPYTYSQLQQILRSRLKHLKAFEDDAIQLVARKVAALSGDAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RIMMNRVSSRLGLTRMCFQPYTYSQLQQILRSRLKHLKAFEDDAIQLVARKVAALSGDAR 630 640 650 660 670 680 730 740 750 760 770 780 pF1KB8 RCLDICRRATEICEFSQQKPDSPGLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RCLDICRRATEICEFSQQKPDSPGLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLRA 690 700 710 720 730 740 790 800 810 820 830 840 pF1KB8 ILAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSHLGSCRLLLVEPSRND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSHLGSCRLLLVEPSRND 750 760 770 780 790 800 850 860 pF1KB8 LLLRVRLNVSQDDVLYALKDE ::::::::::::::::::::: XP_016 LLLRVRLNVSQDDVLYALKDE 810 820 >>XP_011539829 (OMIM: 224690,601902) PREDICTED: origin r (501 aa) initn: 3251 init1: 3251 opt: 3251 Z-score: 2643.4 bits: 499.4 E(85289): 1.7e-140 Smith-Waterman score: 3251; 100.0% identity (100.0% similar) in 500 aa overlap (362-861:2-501) 340 350 360 370 380 390 pF1KB8 EERTLTPISGGQRSSVVPSVILKPENIKKRDAKEAKAQNEATSTPHRIRRKSSVLTMNRI :::::::::::::::::::::::::::::: XP_011 MDAKEAKAQNEATSTPHRIRRKSSVLTMNRI 10 20 30 400 410 420 430 440 450 pF1KB8 RQQLRFLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLRSSLKSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RQQLRFLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLRSSLKSSL 40 50 60 70 80 90 460 470 480 490 500 510 pF1KB8 HTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQEPASVLEEARLRLHVSAVPESLPCREQEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQEPASVLEEARLRLHVSAVPESLPCREQEF 100 110 120 130 140 150 520 530 540 550 560 570 pF1KB8 QDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQANDVPPFQYIEVNGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQANDVPPFQYIEVNGM 160 170 180 190 200 210 580 590 600 610 620 630 pF1KB8 KLTEPHQVYVQILQKLTGQKATANHAAELLAKQFCTRGSPQETTVLLVDELDLLWTHKQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLTEPHQVYVQILQKLTGQKATANHAAELLAKQFCTRGSPQETTVLLVDELDLLWTHKQD 220 230 240 250 260 270 640 650 660 670 680 690 pF1KB8 IMYNLFDWPTHKEARLVVLAIANTMDLPERIMMNRVSSRLGLTRMCFQPYTYSQLQQILR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IMYNLFDWPTHKEARLVVLAIANTMDLPERIMMNRVSSRLGLTRMCFQPYTYSQLQQILR 280 290 300 310 320 330 700 710 720 730 740 750 pF1KB8 SRLKHLKAFEDDAIQLVARKVAALSGDARRCLDICRRATEICEFSQQKPDSPGLVTIAHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SRLKHLKAFEDDAIQLVARKVAALSGDARRCLDICRRATEICEFSQQKPDSPGLVTIAHS 340 350 360 370 380 390 760 770 780 790 800 810 pF1KB8 MEAVDEMFSSSYITAIKNSSVLEQSFLRAILAEFRRSGLEEATFQQIYSQHVALCRMEGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MEAVDEMFSSSYITAIKNSSVLEQSFLRAILAEFRRSGLEEATFQQIYSQHVALCRMEGL 400 410 420 430 440 450 820 830 840 850 860 pF1KB8 PYPTMSETMAVCSHLGSCRLLLVEPSRNDLLLRVRLNVSQDDVLYALKDE :::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PYPTMSETMAVCSHLGSCRLLLVEPSRNDLLLRVRLNVSQDDVLYALKDE 460 470 480 490 500 >>NP_001245 (OMIM: 602627,613805) cell division control (560 aa) initn: 353 init1: 167 opt: 516 Z-score: 429.4 bits: 89.9 E(85289): 3.5e-17 Smith-Waterman score: 604; 28.3% identity (62.3% similar) in 467 aa overlap (422-861:99-548) 400 410 420 430 440 450 pF1KB8 RQQLRFLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLRSSLKSSL :.. . : :. .. . .. ::...: NP_001 HLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKILSSVRKSQ 70 80 90 100 110 120 460 470 480 490 500 510 pF1KB8 HTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQEPASVLEEARLRLHVSAVPESLPCREQEF . :. .. . : .: : :: .. ..:.: :. .:::. :: ::.:. NP_001 EITTNSEQRCPLKKESAC----VR---LFKQE-GTCYQQAKLVLN-TAVPDRLPAREREM 130 140 150 160 170 520 530 540 550 560 570 pF1KB8 QDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQANDVPPFQYIEVNGM . : ::.. .. . .: .:.::.::::::: . .... :.. .. :. : .: : NP_001 DVIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKK-----ELKGFKTIMLNCM 180 190 200 210 220 230 580 590 600 610 620 pF1KB8 KLTEPHQVYVQILQKLTGQKATANHAAEL---LAKQFCTRGSPQETTVLLVDELDLLWTH .: . :. : :.. .... . .. : :.. .. .:. ::..::.: : .. NP_001 SLRTAQAVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPM--IVLVLDEMDQLDSK 240 250 260 270 280 290 630 640 650 660 670 680 pF1KB8 KQDIMYNLFDWPTHKEARLVVLAIANTMDLPERIMMNRVSSRLGLTR--MCFQPYTYSQL ::..:.::.:: ....::...::::.:: .::. :...: . : ::: .:. NP_001 GQDVLYTLFEWPWLSNSHLVLIGIANTLDLTDRIL-PRLQAREKCKPQLLNFPPYTRNQI 300 310 320 330 340 350 690 700 710 720 730 pF1KB8 QQILRSRLKHL---KAFEDDAIQLVARKVAALSGDARRCLDICRRATEICEF---SQ--- ::..::... ..... :.:. ::::.:.:::.:. ::.:::: :: : :: NP_001 VTILQDRLNQVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRRAIEIVESDVKSQTIL 360 370 380 390 400 410 740 750 760 770 780 pF1KB8 ------QKPDSP------GLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLR-AILAE ..:. : ::. :.. . :: . . ..: :.:..: ... NP_001 KPLSECKSPSEPLIPKRVGLIHISQVISEVDGNRMTLSQEGAQDSFPLQQKILVCSLMLL 420 430 440 450 460 470 790 800 810 820 830 840 pF1KB8 FRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSHLGSCRLLLVEPSRNDLLLR .:. ..:.:. ..: . .:: . . .:: ... . : . .: .. ... : . NP_001 IRQLKIKEVTLGKLYEAYSKVCRKQQVAAVDQSECLSLSGLLEARGILGLKRNKETRLTK 480 490 500 510 520 530 850 860 pF1KB8 VRLNVSQDDVLYALKDE : ... . .. .::::. NP_001 VFFKIEEKEIEHALKDKALIGNILATGLP 540 550 560 >>XP_011523844 (OMIM: 602627,613805) PREDICTED: cell div (600 aa) initn: 353 init1: 167 opt: 492 Z-score: 409.5 bits: 86.3 E(85289): 4.5e-16 Smith-Waterman score: 502; 31.1% identity (66.0% similar) in 315 aa overlap (422-728:99-396) 400 410 420 430 440 450 pF1KB8 RQQLRFLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLRSSLKSSL :.. . : :. .. . .. ::...: XP_011 HLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKILSSVRKSQ 70 80 90 100 110 120 460 470 480 490 500 510 pF1KB8 HTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQEPASVLEEARLRLHVSAVPESLPCREQEF . :. .. . : .: : :: .. ..:.: :. .:::. :: ::.:. XP_011 EITTNSEQRCPLKKESAC----VR---LFKQE-GTCYQQAKLVLN-TAVPDRLPAREREM 130 140 150 160 170 520 530 540 550 560 570 pF1KB8 QDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQANDVPPFQYIEVNGM . : ::.. .. . .: .:.::.::::::: . .... :.. .. :. : .: : XP_011 DVIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKK-----ELKGFKTIMLNCM 180 190 200 210 220 230 580 590 600 610 620 pF1KB8 KLTEPHQVYVQILQKLTGQKATANHAAEL---LAKQFCTRGSPQETTVLLVDELDLLWTH .: . :. : :.. .... . .. : :.. .. .:. ::..::.: : .. XP_011 SLRTAQAVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPM--IVLVLDEMDQLDSK 240 250 260 270 280 290 630 640 650 660 670 680 pF1KB8 KQDIMYNLFDWPTHKEARLVVLAIANTMDLPERIMMNRVSSRLGLTR--MCFQPYTYSQL ::..:.::.:: ....::...::::.:: .::. :...: . : ::: .:. XP_011 GQDVLYTLFEWPWLSNSHLVLIGIANTLDLTDRIL-PRLQAREKCKPQLLNFPPYTRNQI 300 310 320 330 340 350 690 700 710 720 730 740 pF1KB8 QQILRSRLKHL---KAFEDDAIQLVARKVAALSGDARRCLDICRRATEICEFSQQKPDSP ::..::... ..... :.:. ::::.:.:::.:. ::.::. XP_011 VTILQDRLNQVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRKEDLFLSGELWISTVL 360 370 380 390 400 410 750 760 770 780 790 800 pF1KB8 GLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLRAILAEFRRSGLEEATFQQIYSQHV XP_011 MSETLSVHYLQREKQMRCCWHSLWRAIEIVESDVKSQTILKPLSECKSPSEPLIPKRVGL 420 430 440 450 460 470 >>XP_011523843 (OMIM: 602627,613805) PREDICTED: cell div (600 aa) initn: 353 init1: 167 opt: 492 Z-score: 409.5 bits: 86.3 E(85289): 4.5e-16 Smith-Waterman score: 502; 31.1% identity (66.0% similar) in 315 aa overlap (422-728:99-396) 400 410 420 430 440 450 pF1KB8 RQQLRFLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLRSSLKSSL :.. . : :. .. . .. ::...: XP_011 HLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKILSSVRKSQ 70 80 90 100 110 120 460 470 480 490 500 510 pF1KB8 HTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQEPASVLEEARLRLHVSAVPESLPCREQEF . :. .. . : .: : :: .. ..:.: :. .:::. :: ::.:. XP_011 EITTNSEQRCPLKKESAC----VR---LFKQE-GTCYQQAKLVLN-TAVPDRLPAREREM 130 140 150 160 170 520 530 540 550 560 570 pF1KB8 QDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQANDVPPFQYIEVNGM . : ::.. .. . .: .:.::.::::::: . .... :.. .. :. : .: : XP_011 DVIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKK-----ELKGFKTIMLNCM 180 190 200 210 220 230 580 590 600 610 620 pF1KB8 KLTEPHQVYVQILQKLTGQKATANHAAEL---LAKQFCTRGSPQETTVLLVDELDLLWTH .: . :. : :.. .... . .. : :.. .. .:. ::..::.: : .. XP_011 SLRTAQAVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPM--IVLVLDEMDQLDSK 240 250 260 270 280 290 630 640 650 660 670 680 pF1KB8 KQDIMYNLFDWPTHKEARLVVLAIANTMDLPERIMMNRVSSRLGLTR--MCFQPYTYSQL ::..:.::.:: ....::...::::.:: .::. :...: . : ::: .:. XP_011 GQDVLYTLFEWPWLSNSHLVLIGIANTLDLTDRIL-PRLQAREKCKPQLLNFPPYTRNQI 300 310 320 330 340 350 690 700 710 720 730 740 pF1KB8 QQILRSRLKHL---KAFEDDAIQLVARKVAALSGDARRCLDICRRATEICEFSQQKPDSP ::..::... ..... :.:. ::::.:.:::.:. ::.::. XP_011 VTILQDRLNQVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRKEDLFLSGELWISTVL 360 370 380 390 400 410 750 760 770 780 790 800 pF1KB8 GLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLRAILAEFRRSGLEEATFQQIYSQHV XP_011 MSETLSVHYLQREKQMRCCWHSLWRAIEIVESDVKSQTILKPLSECKSPSEPLIPKRVGL 420 430 440 450 460 470 861 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:29:39 2016 done: Sat Nov 5 16:29:41 2016 Total Scan time: 14.400 Total Display time: 0.200 Function used was FASTA [36.3.4 Apr, 2011]