Result of FASTA (ccds) for
pF1KB8499
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8499, 932 aa
1>>>pF1KB8499 932 - 932 aa - 932 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6848+/-0.00142; mu= 9.4829+/- 0.084
mean_var=121.7960+/-24.331, 0's: 0 Z-trim(101.7): 69 B-trim: 44 in 1/48
Lambda= 0.116214
statistics sampled from 6575 (6617) to 6575 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.53), E-opt: 0.2 (0.203), width: 16
Scan time: 4.260
The best scores are: opt bits E(32554)
CCDS2302.1 PMS1 gene_id:5378|Hs108|chr2 ( 932) 6068 1029.8 0
CCDS74615.1 PMS1 gene_id:5378|Hs108|chr2 ( 756) 4962 844.4 0
CCDS46474.1 PMS1 gene_id:5378|Hs108|chr2 ( 893) 4593 782.5 0
CCDS46473.1 PMS1 gene_id:5378|Hs108|chr2 ( 770) 4003 683.6 3.9e-196
CCDS82544.1 PMS1 gene_id:5378|Hs108|chr2 ( 181) 884 160.4 2.8e-39
CCDS82543.1 PMS1 gene_id:5378|Hs108|chr2 ( 165) 882 160.1 3.3e-39
CCDS5343.1 PMS2 gene_id:5395|Hs108|chr7 ( 862) 468 90.9 1.1e-17
CCDS2663.1 MLH1 gene_id:4292|Hs108|chr3 ( 756) 380 76.1 2.8e-13
>>CCDS2302.1 PMS1 gene_id:5378|Hs108|chr2 (932 aa)
initn: 6068 init1: 6068 opt: 6068 Z-score: 5504.5 bits: 1029.8 E(32554): 0
Smith-Waterman score: 6068; 100.0% identity (100.0% similar) in 932 aa overlap (1-932:1-932)
10 20 30 40 50 60
pF1KB8 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 ATLQIEELWKTLSEEEKLKYEEKATKDLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 ATLQIEELWKTLSEEEKLKYEEKATKDLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAW
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 NLAQKHKLKTSLSNQPKLDELLQSQIEKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 NLAQKHKLKTSLSNQPKLDELLQSQIEKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 KDEPCLIHNLRFPDAWLMTSKTEVMLLNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 KDEPCLIHNLRFPDAWLMTSKTEVMLLNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 SLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTANGFKIKLIPGVSITENYLEIEGMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 SLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTANGFKIKLIPGVSITENYLEIEGMAN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB8 CLPFYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 CLPFYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDI
850 860 870 880 890 900
910 920 930
pF1KB8 IYRMKHQFGNEIKECVHGRPFFHHLTYLPETT
::::::::::::::::::::::::::::::::
CCDS23 IYRMKHQFGNEIKECVHGRPFFHHLTYLPETT
910 920 930
>>CCDS74615.1 PMS1 gene_id:5378|Hs108|chr2 (756 aa)
initn: 4962 init1: 4962 opt: 4962 Z-score: 4503.8 bits: 844.4 E(32554): 0
Smith-Waterman score: 4962; 100.0% identity (100.0% similar) in 756 aa overlap (177-932:1-756)
150 160 170 180 190 200
pF1KB8 RLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFGILKPDLRIVFVHNKAVIWQKSRVSDH
::::::::::::::::::::::::::::::
CCDS74 MSFGILKPDLRIVFVHNKAVIWQKSRVSDH
10 20 30
210 220 230 240 250 260
pF1KB8 KMALMSVLGTAVMNNMESFQYHSEESQIYLSGFLPKCDADHSFTSLSTPERSFIFINSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 KMALMSVLGTAVMNNMESFQYHSEESQIYLSGFLPKCDADHSFTSLSTPERSFIFINSRP
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB8 VHQKDILKLIRHHYNLKCLKESTRLYPVFFLKIDVPTADVDVNLTPDKSQVLLQNKESVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 VHQKDILKLIRHHYNLKCLKESTRLYPVFFLKIDVPTADVDVNLTPDKSQVLLQNKESVL
100 110 120 130 140 150
330 340 350 360 370 380
pF1KB8 IALENLMTTCYGPLPSTNSYENNKTDVSAADIVLSKTAETDVLFNKVESSGKNYSNVDTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 IALENLMTTCYGPLPSTNSYENNKTDVSAADIVLSKTAETDVLFNKVESSGKNYSNVDTS
160 170 180 190 200 210
390 400 410 420 430 440
pF1KB8 VIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGHCSSEISNIDKNTKNAFQDISMSNVSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 VIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGHCSSEISNIDKNTKNAFQDISMSNVSW
220 230 240 250 260 270
450 460 470 480 490 500
pF1KB8 ENSQTEYSKTCFISSVKHTQSENGNKDHIDESGENEEEAGLENSSEISADEWSRGNILKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 ENSQTEYSKTCFISSVKHTQSENGNKDHIDESGENEEEAGLENSSEISADEWSRGNILKN
280 290 300 310 320 330
510 520 530 540 550 560
pF1KB8 SVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMNLNEDSCNKKSNVIDNKSGKVTAYDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 SVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMNLNEDSCNKKSNVIDNKSGKVTAYDLL
340 350 360 370 380 390
570 580 590 600 610 620
pF1KB8 SNRVIKKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEKLKYEEKATK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 SNRVIKKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEKLKYEEKATK
400 410 420 430 440 450
630 640 650 660 670 680
pF1KB8 DLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAWNLAQKHKLKTSLSNQPKLDELLQSQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 DLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAWNLAQKHKLKTSLSNQPKLDELLQSQI
460 470 480 490 500 510
690 700 710 720 730 740
pF1KB8 EKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEEKDEPCLIHNLRFPDAWLMTSKTEVML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 EKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEEKDEPCLIHNLRFPDAWLMTSKTEVML
520 530 540 550 560 570
750 760 770 780 790 800
pF1KB8 LNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTESLFNGSHYLDVLYKMTADDQRYSGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 LNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTESLFNGSHYLDVLYKMTADDQRYSGST
580 590 600 610 620 630
810 820 830 840 850 860
pF1KB8 YLSDPRLTANGFKIKLIPGVSITENYLEIEGMANCLPFYGVADLKEILNAILNRNAKEVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 YLSDPRLTANGFKIKLIPGVSITENYLEIEGMANCLPFYGVADLKEILNAILNRNAKEVY
640 650 660 670 680 690
870 880 890 900 910 920
pF1KB8 ECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDIIYRMKHQFGNEIKECVHGRPFFHHLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 ECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDIIYRMKHQFGNEIKECVHGRPFFHHLT
700 710 720 730 740 750
930
pF1KB8 YLPETT
::::::
CCDS74 YLPETT
>>CCDS46474.1 PMS1 gene_id:5378|Hs108|chr2 (893 aa)
initn: 4593 init1: 4593 opt: 4593 Z-score: 4168.3 bits: 782.5 E(32554): 0
Smith-Waterman score: 5728; 95.8% identity (95.8% similar) in 932 aa overlap (1-932:1-893)
10 20 30 40 50 60
pF1KB8 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL
:::::::::::::: :::::::
CCDS46 ILKPDLRIVFVHNK---------------------------------------IYLSGFL
190 200
250 260 270 280 290 300
pF1KB8 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID
210 220 230 240 250 260
310 320 330 340 350 360
pF1KB8 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL
270 280 290 300 310 320
370 380 390 400 410 420
pF1KB8 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH
330 340 350 360 370 380
430 440 450 460 470 480
pF1KB8 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE
390 400 410 420 430 440
490 500 510 520 530 540
pF1KB8 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN
450 460 470 480 490 500
550 560 570 580 590 600
pF1KB8 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED
510 520 530 540 550 560
610 620 630 640 650 660
pF1KB8 ATLQIEELWKTLSEEEKLKYEEKATKDLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 ATLQIEELWKTLSEEEKLKYEEKATKDLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAW
570 580 590 600 610 620
670 680 690 700 710 720
pF1KB8 NLAQKHKLKTSLSNQPKLDELLQSQIEKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 NLAQKHKLKTSLSNQPKLDELLQSQIEKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEE
630 640 650 660 670 680
730 740 750 760 770 780
pF1KB8 KDEPCLIHNLRFPDAWLMTSKTEVMLLNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 KDEPCLIHNLRFPDAWLMTSKTEVMLLNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTE
690 700 710 720 730 740
790 800 810 820 830 840
pF1KB8 SLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTANGFKIKLIPGVSITENYLEIEGMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 SLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTANGFKIKLIPGVSITENYLEIEGMAN
750 760 770 780 790 800
850 860 870 880 890 900
pF1KB8 CLPFYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 CLPFYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDI
810 820 830 840 850 860
910 920 930
pF1KB8 IYRMKHQFGNEIKECVHGRPFFHHLTYLPETT
::::::::::::::::::::::::::::::::
CCDS46 IYRMKHQFGNEIKECVHGRPFFHHLTYLPETT
870 880 890
>>CCDS46473.1 PMS1 gene_id:5378|Hs108|chr2 (770 aa)
initn: 4999 init1: 4003 opt: 4003 Z-score: 3634.7 bits: 683.6 E(32554): 3.9e-196
Smith-Waterman score: 4679; 82.5% identity (82.6% similar) in 932 aa overlap (1-932:1-770)
10 20 30 40 50 60
pF1KB8 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 ATLQIEELWKTLSEEEKLKYEEKATKDLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAW
::::::::::::::::::
CCDS46 ATLQIEELWKTLSEEEKL------------------------------------------
610
670 680 690 700 710 720
pF1KB8 NLAQKHKLKTSLSNQPKLDELLQSQIEKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEE
CCDS46 ------------------------------------------------------------
730 740 750 760 770 780
pF1KB8 KDEPCLIHNLRFPDAWLMTSKTEVMLLNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTE
CCDS46 ------------------------------------------------------------
790 800 810 820 830 840
pF1KB8 SLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTANGFKIKLIPGVSITENYLEIEGMAN
.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 NLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTANGFKIKLIPGVSITENYLEIEGMAN
620 630 640 650 660 670
850 860 870 880 890 900
pF1KB8 CLPFYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 CLPFYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDI
680 690 700 710 720 730
910 920 930
pF1KB8 IYRMKHQFGNEIKECVHGRPFFHHLTYLPETT
::::::::::::::::::::::::::::::::
CCDS46 IYRMKHQFGNEIKECVHGRPFFHHLTYLPETT
740 750 760 770
>>CCDS82544.1 PMS1 gene_id:5378|Hs108|chr2 (181 aa)
initn: 883 init1: 883 opt: 884 Z-score: 818.6 bits: 160.4 E(32554): 2.8e-39
Smith-Waterman score: 884; 94.1% identity (96.1% similar) in 152 aa overlap (1-152:1-149)
10 20 30 40 50 60
pF1KB8 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG
:::::::::::::::::::: :. :. :.
CCDS82 YVLDGSGHILSQKPSHLGQGKKVA---LYTNILYLFCLNCWFKKKKLLGEYKYIALGLVL
130 140 150 160 170
190 200 210 220 230 240
pF1KB8 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL
CCDS82 IKAS
180
>>CCDS82543.1 PMS1 gene_id:5378|Hs108|chr2 (165 aa)
initn: 882 init1: 882 opt: 882 Z-score: 817.5 bits: 160.1 E(32554): 3.3e-39
Smith-Waterman score: 882; 99.3% identity (100.0% similar) in 141 aa overlap (1-141:1-141)
10 20 30 40 50 60
pF1KB8 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG
::::::::::::::::::::.
CCDS82 YVLDGSGHILSQKPSHLGQGSHSVTQAGLQWHHLGSLQPLPPRLK
130 140 150 160
>>CCDS5343.1 PMS2 gene_id:5395|Hs108|chr7 (862 aa)
initn: 623 init1: 441 opt: 468 Z-score: 430.8 bits: 90.9 E(32554): 1.1e-17
Smith-Waterman score: 625; 26.4% identity (57.9% similar) in 632 aa overlap (1-580:15-625)
10 20 30 40
pF1KB8 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLEN
.: . .:. . :.:.. :. ..::::.:::::::::..:.::..
CCDS53 MERAESSSTEPAKAIKPIDRKSVHQICSGQVVLSLSTAVKELVENSLDAGATNIDLKLKD
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB8 YGFDKIEVRDNGEGIKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEV
:: : ::: ::: :.. . ...:..::::. :: .. :.:::::::.:.: ...:
CCDS53 YGVDLIEVSDNGCGVEEENFEGLTLKHHTSKIQEFADLTQVETFGFRGEALSSLCALSDV
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB8 LITTRTAADNFSTQYVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVR-KQFYSTAKKC
:.: :. . .:. ..: .:.:... : .::::.. .::..:::: :.: . ::
CCDS53 TISTCHASAKVGTRLMFDHNGKIIQKTPYPRPRGTTVSVQQLFSTLPVRHKEFQRNIKK-
130 140 150 160 170
170 180 190 200 210 220
pF1KB8 KDEIKKIQDLLMSFGILKPDLRIVFVHNKAVIWQKSRVSDH-----KMALMSVLGTAVMN
: :. ..: .. :.. .:. ... . .. : : . ::.: ..
CCDS53 --EYAKMVQVLHAYCIISAGIRVSCTNQLGQGKRQPVVCTGGSPSIKENIGSVFGQKQLQ
180 190 200 210 220 230
230 240 250 260
pF1KB8 NMESF-QYHSEES---------------QIYLSGFLPKCDADHSFTSLSTPERSFIFINS
.. : : .: .:.:::. .: :. .. :. .:.:.:::
CCDS53 SLIPFVQLPPSDSVCEEYGLSCSDALHNLFYISGFISQCT--HG-VGRSSTDRQFFFINR
240 250 260 270 280 290
270 280 290 300 310 320
pF1KB8 RPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKIDVPTADVDVNLTPDKSQVLLQNKES
:: . .:. . :.. . . :: :.:.: . ::.:.:::: :.::: .:.
CCDS53 RPCDPAKVCRLVNEVYHMY----NRHQYPFVVLNISVDSECVDINVTPDKRQILLQ-EEK
300 310 320 330 340
330 340 350 360 370
pF1KB8 VLIALENLMTTCYGPLPSTNSYENNKTDVSAADIV-----LSKTAETDVLFNKVESSGKN
.:.:. : :. : . : . :: .:: .. : : .:. ::.. ..
CCDS53 LLLAV--LKTSLIGMFDS----DVNKLNVSQQPLLDVEGNLIKMHAADLEKPMVEKQDQS
350 360 370 380 390 400
380 390 400 410 420 430
pF1KB8 YS------NVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGHCSSEISNIDKNTK
: . :.:. . ... : ..: . :. . . . ... . ....:.
CCDS53 PSLRTGEEKKDVSI----SRLREAFSLRHTTENKPHSPKTPEPRRSPLGQKRGMLSSSTS
410 420 430 440 450
440 450 460 470 480 490
pF1KB8 NAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGENEEEAGLENSSEI
.:..: .. . : .. .. . . .. .. . .. .: : . ..: . :::
CCDS53 GAISDKGVLRPQKEAVSSSHGPSDPTDRAEVEKDSGHGSTSVDSEGFSIPDTGSHCSSEY
460 470 480 490 500 510
500 510 520 530
pF1KB8 SA----DEWSRGNILKN----SVGENIEPVKILVPEKSLPCKV----SNNNYPIP-----
.: :. :. .. .. .. ... : ... :: . .: :
CCDS53 AASSPGDRGSQEHVDSQEKAPKTDDSFSDVDCHSNQEDTGCKFRVLPQPTNLATPNTKRF
520 530 540 550 560 570
540 550 560 570 580 590
pF1KB8 --EQMNLNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENP
:.. . : :.: :. : ....: . ....:. .: :.:
CCDS53 KKEEILSSSDICQKLVNTQDMSASQVDVAVKINKKVVPLDFSMSSLAKRIKQLHHEAQQS
580 590 600 610 620 630
600 610 620 630 640 650
pF1KB8 KTSLEDATLQIEELWKTLSEEEKLKYEEKATKDLERYNSQMKRAIEQESQMSLKDGRKKI
CCDS53 EGEQNYRKFRAKICPGENQAAEDELRKEISKTMFAEMEIIGQFNLGFIITKLNEDIFIVD
640 650 660 670 680 690
>>CCDS2663.1 MLH1 gene_id:4292|Hs108|chr3 (756 aa)
initn: 373 init1: 324 opt: 380 Z-score: 352.0 bits: 76.1 E(32554): 2.8e-13
Smith-Waterman score: 439; 22.0% identity (55.7% similar) in 738 aa overlap (1-675:8-727)
10 20 30 40 50
pF1KB8 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIE
...: ..: ......: ....::.::: ::: .::..: ... :. :.
CCDS26 MSFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 VRDNGEGIKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTA
..::: ::. : .. .. :::..: ::: ...:::::::::.:: .:.: :::.::
CCDS26 IQDNGTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 ADNFSTQYVLDGSGHILSQ-KPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKI
:. . . ..:.. . :: .::: .:. :: :. .:.. . :. ..: ::
CCDS26 -DGKCAYRASYSDGKLKAPPKPCAGNQGTQITVEDLFYNIATRRK---ALKNPSEEYGKI
130 140 150 160 170
180 190 200 210 220 230
pF1KB8 QDLLMSFGILKPDLRIVFVHNKAVIWQKSRVSDHKMA--LMSVLGTAVMNNMESFQYHSE
... ... . . . .. .. . . . . . . :..:.:: .. . ...
CCDS26 LEVVGRYSVHNAGISFSVKKQGETVADVRTLPNASTVDNIRSIFGNAVSRELIEIGCEDK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 ESQIYLSGFLPKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTR
. ..:.. .:..: . ..::: : :.. .. : :. : :..
CCDS26 TLAFKMNGYIS--NANYSVKKCIF----LLFINHRLVESTSLRKAIETVYAAYLPKNT--
240 250 260 270 280
300 310 320 330
pF1KB8 LYPVFFLKIDVPTADVDVNLTPDKSQVLLQNKESVLIALEN-------------------
.: ..:.... .::::. : : .: . ..::.: ...
CCDS26 -HPFLYLSLEISPQNVDVNVHPTKHEVHFLHEESILERVQQHIESKLLGSNSSRMYFTQT
290 300 310 320 330 340
340 350 360 370 380
pF1KB8 LMTTCYGP----LPSTNSYENNKTDVSAADIVLSKTAETDVLFNKVESS----GKNYSNV
:. :: . ::.: ...:. :. . . ..:: .:... .: :.
CCDS26 LLPGLAGPSGEMVKSTTSLTSSSTSGSSDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQ
350 360 370 380 390 400
390 400 410 420
pF1KB8 DTSVIPF-QNDMHNDESGKNTDDCLN----------HQISIGDFGYGHCSSEISN----I
... ..:. . .. .. .. :. .: :: : .::.:.
CCDS26 PQAIVTEDKTDISSGRARQQDEEMLELPAPAEVAAKNQSLEGDTTKG--TSEMSEKRGPT
410 420 430 440 450 460
430 440 450 460 470
pF1KB8 DKNTKNAFQDISMSNVSWENSQTEYSKTCF-------ISSVKHTQSENGNKDH--IDESG
..: .. .. : .. ..:. :.. .: ..:: : : ... : . :
CCDS26 SSNPRKRHREDSDVEMVEDDSRKEMTAACTPRRRIINLTSVLSLQEEINEQGHEVLREML
470 480 490 500 510 520
480 490 500 510 520 530
pF1KB8 ENEEEAGLENSSEISADEWSRGNILKNS-VGENIEPVKILVPE-KSLPCKVSNNNYPIPE
.:. .: : . :.. .. .:... ..:.. .::. . .. .. :. .
CCDS26 HNHSFVGCVNPQWALAQHQTKLYLLNTTKLSEELF-YQILIYDFANFGVLRLSEPAPLFD
530 540 550 560 570 580
540 550 560 570 580 590
pF1KB8 QMNLNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKP-MSASALFVQ-DHRPQF-----L
: :: .:. .. . : . . . . :: : :. . .. :.. .. :
CCDS26 LAMLALDS--PESGWTEEDGPKEGLAEYIVEFLKKKAEMLADYFSLEIDEEGNLIGLPLL
590 600 610 620 630 640
600 610 620 630 640 650
pF1KB8 IENPKTSLEDATLQIEELWKTLSEEEKLKYEEKATKDLERYNSQMKRAIEQESQMSLKDG
:.: :: . : .: .. .:. . :. .:. . : :. : .:: .: ...
CCDS26 IDNYVPPLEGLPIFILRLATEVNWDEEKECFESLSKECAMFYSIRKQYISEESTLSGQQS
650 660 670 680 690 700
660 670 680 690 700 710
pF1KB8 RKKIKPTSAWNLAQKHKLKTSLSNQPKLDELLQSQIEKRRSQNIKMVQIPFSMKNLKINF
. . ..:. . .: . .: ..
CCDS26 EVPGSIPNSWKWTVEHIVYKALRSHILPPKHFTEDGNILQLANLPDLYKVFERC
710 720 730 740 750
932 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 18:09:55 2016 done: Sun Nov 6 18:09:56 2016
Total Scan time: 4.260 Total Display time: 0.190
Function used was FASTA [36.3.4 Apr, 2011]