FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8499, 932 aa
1>>>pF1KB8499 932 - 932 aa - 932 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8068+/-0.000577; mu= 15.3762+/- 0.035
mean_var=149.6677+/-30.777, 0's: 0 Z-trim(108.8): 108 B-trim: 840 in 1/52
Lambda= 0.104836
statistics sampled from 16841 (16929) to 16841 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.521), E-opt: 0.2 (0.198), width: 16
Scan time: 10.810
The best scores are: opt bits E(85289)
NP_001307974 (OMIM: 120435,600258) PMS1 protein ho ( 932) 6068 931.3 0
NP_000525 (OMIM: 120435,600258) PMS1 protein homol ( 932) 6068 931.3 0
NP_001307977 (OMIM: 120435,600258) PMS1 protein ho ( 932) 6068 931.3 0
NP_001307976 (OMIM: 120435,600258) PMS1 protein ho ( 932) 6068 931.3 0
NP_001307975 (OMIM: 120435,600258) PMS1 protein ho ( 871) 5413 832.2 0
XP_016859835 (OMIM: 120435,600258) PREDICTED: PMS1 ( 871) 5413 832.2 0
XP_016859834 (OMIM: 120435,600258) PREDICTED: PMS1 ( 871) 5413 832.2 0
NP_001276337 (OMIM: 120435,600258) PMS1 protein ho ( 756) 4962 763.9 0
XP_011509658 (OMIM: 120435,600258) PREDICTED: PMS1 ( 756) 4962 763.9 0
NP_001276338 (OMIM: 120435,600258) PMS1 protein ho ( 756) 4962 763.9 0
XP_006712659 (OMIM: 120435,600258) PREDICTED: PMS1 ( 747) 4842 745.8 1.9e-214
XP_016859838 (OMIM: 120435,600258) PREDICTED: PMS1 ( 717) 4593 708.1 4e-203
XP_016859836 (OMIM: 120435,600258) PREDICTED: PMS1 ( 832) 4593 708.2 4.4e-203
NP_001121615 (OMIM: 120435,600258) PMS1 protein ho ( 893) 4593 708.2 4.6e-203
XP_016859833 (OMIM: 120435,600258) PREDICTED: PMS1 ( 893) 4593 708.2 4.6e-203
NP_001121616 (OMIM: 120435,600258) PMS1 protein ho ( 770) 4003 618.9 3e-176
XP_016859837 (OMIM: 120435,600258) PREDICTED: PMS1 ( 770) 4003 618.9 3e-176
XP_016859839 (OMIM: 120435,600258) PREDICTED: PMS1 ( 709) 3348 519.8 1.9e-146
XP_016859840 (OMIM: 120435,600258) PREDICTED: PMS1 ( 594) 2897 451.5 5.7e-126
NP_001307973 (OMIM: 120435,600258) PMS1 protein ho ( 731) 2528 395.8 4.2e-109
NP_001307978 (OMIM: 120435,600258) PMS1 protein ho ( 181) 884 146.6 1.1e-34
NP_001307980 (OMIM: 120435,600258) PMS1 protein ho ( 165) 882 146.2 1.3e-34
NP_001308935 (OMIM: 276300,600259,614337) mismatch ( 810) 468 84.3 2.8e-15
NP_000526 (OMIM: 276300,600259,614337) mismatch re ( 862) 468 84.3 2.9e-15
NP_001308943 (OMIM: 276300,600259,614337) mismatch ( 873) 468 84.3 2.9e-15
NP_001245200 (OMIM: 120436,158320,276300,609310) D ( 687) 380 70.9 2.5e-11
NP_000240 (OMIM: 120436,158320,276300,609310) DNA ( 756) 380 70.9 2.7e-11
XP_005265218 (OMIM: 120436,158320,276300,609310) P ( 687) 351 66.5 5.3e-10
XP_011534950 (OMIM: 604395,608089,614385) PREDICTE (1157) 308 60.2 6.9e-08
XP_005267591 (OMIM: 604395,608089,614385) PREDICTE (1275) 308 60.2 7.4e-08
XP_005267590 (OMIM: 604395,608089,614385) PREDICTE (1394) 308 60.3 7.9e-08
XP_011534948 (OMIM: 604395,608089,614385) PREDICTE (1396) 308 60.3 7.9e-08
XP_005267589 (OMIM: 604395,608089,614385) PREDICTE (1418) 308 60.3 8e-08
NP_055196 (OMIM: 604395,608089,614385) DNA mismatc (1429) 308 60.3 8.1e-08
XP_016876708 (OMIM: 604395,608089,614385) PREDICTE (1429) 308 60.3 8.1e-08
NP_001035197 (OMIM: 604395,608089,614385) DNA mism (1453) 308 60.3 8.2e-08
XP_006720179 (OMIM: 604395,608089,614385) PREDICTE (1453) 308 60.3 8.2e-08
NP_001308942 (OMIM: 276300,600259,614337) mismatch ( 671) 204 44.2 0.0026
NP_001308934 (OMIM: 276300,600259,614337) mismatch ( 727) 204 44.3 0.0027
NP_001308932 (OMIM: 276300,600259,614337) mismatch ( 727) 204 44.3 0.0027
NP_001308933 (OMIM: 276300,600259,614337) mismatch ( 727) 204 44.3 0.0027
NP_001308938 (OMIM: 276300,600259,614337) mismatch ( 738) 204 44.3 0.0027
NP_001308937 (OMIM: 276300,600259,614337) mismatch ( 756) 204 44.3 0.0028
NP_001308936 (OMIM: 276300,600259,614337) mismatch ( 756) 204 44.3 0.0028
NP_001308944 (OMIM: 276300,600259,614337) mismatch ( 759) 204 44.3 0.0028
>>NP_001307974 (OMIM: 120435,600258) PMS1 protein homolo (932 aa)
initn: 6068 init1: 6068 opt: 6068 Z-score: 4972.0 bits: 931.3 E(85289): 0
Smith-Waterman score: 6068; 100.0% identity (100.0% similar) in 932 aa overlap (1-932:1-932)
10 20 30 40 50 60
pF1KB8 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 ATLQIEELWKTLSEEEKLKYEEKATKDLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATLQIEELWKTLSEEEKLKYEEKATKDLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAW
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 NLAQKHKLKTSLSNQPKLDELLQSQIEKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLAQKHKLKTSLSNQPKLDELLQSQIEKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 KDEPCLIHNLRFPDAWLMTSKTEVMLLNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDEPCLIHNLRFPDAWLMTSKTEVMLLNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 SLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTANGFKIKLIPGVSITENYLEIEGMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTANGFKIKLIPGVSITENYLEIEGMAN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB8 CLPFYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLPFYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDI
850 860 870 880 890 900
910 920 930
pF1KB8 IYRMKHQFGNEIKECVHGRPFFHHLTYLPETT
::::::::::::::::::::::::::::::::
NP_001 IYRMKHQFGNEIKECVHGRPFFHHLTYLPETT
910 920 930
>>NP_000525 (OMIM: 120435,600258) PMS1 protein homolog 1 (932 aa)
initn: 6068 init1: 6068 opt: 6068 Z-score: 4972.0 bits: 931.3 E(85289): 0
Smith-Waterman score: 6068; 100.0% identity (100.0% similar) in 932 aa overlap (1-932:1-932)
10 20 30 40 50 60
pF1KB8 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 ATLQIEELWKTLSEEEKLKYEEKATKDLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ATLQIEELWKTLSEEEKLKYEEKATKDLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAW
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 NLAQKHKLKTSLSNQPKLDELLQSQIEKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NLAQKHKLKTSLSNQPKLDELLQSQIEKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 KDEPCLIHNLRFPDAWLMTSKTEVMLLNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KDEPCLIHNLRFPDAWLMTSKTEVMLLNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 SLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTANGFKIKLIPGVSITENYLEIEGMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTANGFKIKLIPGVSITENYLEIEGMAN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB8 CLPFYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 CLPFYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDI
850 860 870 880 890 900
910 920 930
pF1KB8 IYRMKHQFGNEIKECVHGRPFFHHLTYLPETT
::::::::::::::::::::::::::::::::
NP_000 IYRMKHQFGNEIKECVHGRPFFHHLTYLPETT
910 920 930
>>NP_001307977 (OMIM: 120435,600258) PMS1 protein homolo (932 aa)
initn: 6068 init1: 6068 opt: 6068 Z-score: 4972.0 bits: 931.3 E(85289): 0
Smith-Waterman score: 6068; 100.0% identity (100.0% similar) in 932 aa overlap (1-932:1-932)
10 20 30 40 50 60
pF1KB8 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 ATLQIEELWKTLSEEEKLKYEEKATKDLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATLQIEELWKTLSEEEKLKYEEKATKDLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAW
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 NLAQKHKLKTSLSNQPKLDELLQSQIEKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLAQKHKLKTSLSNQPKLDELLQSQIEKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 KDEPCLIHNLRFPDAWLMTSKTEVMLLNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDEPCLIHNLRFPDAWLMTSKTEVMLLNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 SLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTANGFKIKLIPGVSITENYLEIEGMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTANGFKIKLIPGVSITENYLEIEGMAN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB8 CLPFYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLPFYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDI
850 860 870 880 890 900
910 920 930
pF1KB8 IYRMKHQFGNEIKECVHGRPFFHHLTYLPETT
::::::::::::::::::::::::::::::::
NP_001 IYRMKHQFGNEIKECVHGRPFFHHLTYLPETT
910 920 930
>>NP_001307976 (OMIM: 120435,600258) PMS1 protein homolo (932 aa)
initn: 6068 init1: 6068 opt: 6068 Z-score: 4972.0 bits: 931.3 E(85289): 0
Smith-Waterman score: 6068; 100.0% identity (100.0% similar) in 932 aa overlap (1-932:1-932)
10 20 30 40 50 60
pF1KB8 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 ATLQIEELWKTLSEEEKLKYEEKATKDLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATLQIEELWKTLSEEEKLKYEEKATKDLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAW
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 NLAQKHKLKTSLSNQPKLDELLQSQIEKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLAQKHKLKTSLSNQPKLDELLQSQIEKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 KDEPCLIHNLRFPDAWLMTSKTEVMLLNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDEPCLIHNLRFPDAWLMTSKTEVMLLNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 SLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTANGFKIKLIPGVSITENYLEIEGMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTANGFKIKLIPGVSITENYLEIEGMAN
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB8 CLPFYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLPFYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDI
850 860 870 880 890 900
910 920 930
pF1KB8 IYRMKHQFGNEIKECVHGRPFFHHLTYLPETT
::::::::::::::::::::::::::::::::
NP_001 IYRMKHQFGNEIKECVHGRPFFHHLTYLPETT
910 920 930
>>NP_001307975 (OMIM: 120435,600258) PMS1 protein homolo (871 aa)
initn: 5648 init1: 5413 opt: 5413 Z-score: 4437.0 bits: 832.2 E(85289): 0
Smith-Waterman score: 5530; 93.5% identity (93.5% similar) in 932 aa overlap (1-932:1-871)
10 20 30 40 50 60
pF1KB8 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG
::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKL----------------
10 20 30 40
70 80 90 100 110 120
pF1KB8 IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ
:::::::::::::::
NP_001 ---------------------------------------------VLITTRTAADNFSTQ
50
130 140 150 160 170 180
pF1KB8 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG
60 70 80 90 100 110
190 200 210 220 230 240
pF1KB8 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL
120 130 140 150 160 170
250 260 270 280 290 300
pF1KB8 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID
180 190 200 210 220 230
310 320 330 340 350 360
pF1KB8 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL
240 250 260 270 280 290
370 380 390 400 410 420
pF1KB8 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH
300 310 320 330 340 350
430 440 450 460 470 480
pF1KB8 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE
360 370 380 390 400 410
490 500 510 520 530 540
pF1KB8 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN
420 430 440 450 460 470
550 560 570 580 590 600
pF1KB8 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED
480 490 500 510 520 530
610 620 630 640 650 660
pF1KB8 ATLQIEELWKTLSEEEKLKYEEKATKDLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATLQIEELWKTLSEEEKLKYEEKATKDLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAW
540 550 560 570 580 590
670 680 690 700 710 720
pF1KB8 NLAQKHKLKTSLSNQPKLDELLQSQIEKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLAQKHKLKTSLSNQPKLDELLQSQIEKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEE
600 610 620 630 640 650
730 740 750 760 770 780
pF1KB8 KDEPCLIHNLRFPDAWLMTSKTEVMLLNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDEPCLIHNLRFPDAWLMTSKTEVMLLNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTE
660 670 680 690 700 710
790 800 810 820 830 840
pF1KB8 SLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTANGFKIKLIPGVSITENYLEIEGMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTANGFKIKLIPGVSITENYLEIEGMAN
720 730 740 750 760 770
850 860 870 880 890 900
pF1KB8 CLPFYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLPFYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDI
780 790 800 810 820 830
910 920 930
pF1KB8 IYRMKHQFGNEIKECVHGRPFFHHLTYLPETT
::::::::::::::::::::::::::::::::
NP_001 IYRMKHQFGNEIKECVHGRPFFHHLTYLPETT
840 850 860 870
>>XP_016859835 (OMIM: 120435,600258) PREDICTED: PMS1 pro (871 aa)
initn: 5648 init1: 5413 opt: 5413 Z-score: 4437.0 bits: 832.2 E(85289): 0
Smith-Waterman score: 5530; 93.5% identity (93.5% similar) in 932 aa overlap (1-932:1-871)
10 20 30 40 50 60
pF1KB8 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG
::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKL----------------
10 20 30 40
70 80 90 100 110 120
pF1KB8 IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ
:::::::::::::::
XP_016 ---------------------------------------------VLITTRTAADNFSTQ
50
130 140 150 160 170 180
pF1KB8 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG
60 70 80 90 100 110
190 200 210 220 230 240
pF1KB8 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL
120 130 140 150 160 170
250 260 270 280 290 300
pF1KB8 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID
180 190 200 210 220 230
310 320 330 340 350 360
pF1KB8 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL
240 250 260 270 280 290
370 380 390 400 410 420
pF1KB8 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH
300 310 320 330 340 350
430 440 450 460 470 480
pF1KB8 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE
360 370 380 390 400 410
490 500 510 520 530 540
pF1KB8 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN
420 430 440 450 460 470
550 560 570 580 590 600
pF1KB8 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED
480 490 500 510 520 530
610 620 630 640 650 660
pF1KB8 ATLQIEELWKTLSEEEKLKYEEKATKDLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATLQIEELWKTLSEEEKLKYEEKATKDLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAW
540 550 560 570 580 590
670 680 690 700 710 720
pF1KB8 NLAQKHKLKTSLSNQPKLDELLQSQIEKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLAQKHKLKTSLSNQPKLDELLQSQIEKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEE
600 610 620 630 640 650
730 740 750 760 770 780
pF1KB8 KDEPCLIHNLRFPDAWLMTSKTEVMLLNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDEPCLIHNLRFPDAWLMTSKTEVMLLNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTE
660 670 680 690 700 710
790 800 810 820 830 840
pF1KB8 SLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTANGFKIKLIPGVSITENYLEIEGMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTANGFKIKLIPGVSITENYLEIEGMAN
720 730 740 750 760 770
850 860 870 880 890 900
pF1KB8 CLPFYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLPFYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDI
780 790 800 810 820 830
910 920 930
pF1KB8 IYRMKHQFGNEIKECVHGRPFFHHLTYLPETT
::::::::::::::::::::::::::::::::
XP_016 IYRMKHQFGNEIKECVHGRPFFHHLTYLPETT
840 850 860 870
>>XP_016859834 (OMIM: 120435,600258) PREDICTED: PMS1 pro (871 aa)
initn: 5648 init1: 5413 opt: 5413 Z-score: 4437.0 bits: 832.2 E(85289): 0
Smith-Waterman score: 5530; 93.5% identity (93.5% similar) in 932 aa overlap (1-932:1-871)
10 20 30 40 50 60
pF1KB8 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEG
::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKL----------------
10 20 30 40
70 80 90 100 110 120
pF1KB8 IKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQ
:::::::::::::::
XP_016 ---------------------------------------------VLITTRTAADNFSTQ
50
130 140 150 160 170 180
pF1KB8 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVLDGSGHILSQKPSHLGQGTTVTALRLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFG
60 70 80 90 100 110
190 200 210 220 230 240
pF1KB8 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILKPDLRIVFVHNKAVIWQKSRVSDHKMALMSVLGTAVMNNMESFQYHSEESQIYLSGFL
120 130 140 150 160 170
250 260 270 280 290 300
pF1KB8 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKCDADHSFTSLSTPERSFIFINSRPVHQKDILKLIRHHYNLKCLKESTRLYPVFFLKID
180 190 200 210 220 230
310 320 330 340 350 360
pF1KB8 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPTADVDVNLTPDKSQVLLQNKESVLIALENLMTTCYGPLPSTNSYENNKTDVSAADIVL
240 250 260 270 280 290
370 380 390 400 410 420
pF1KB8 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKTAETDVLFNKVESSGKNYSNVDTSVIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGH
300 310 320 330 340 350
430 440 450 460 470 480
pF1KB8 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSSEISNIDKNTKNAFQDISMSNVSWENSQTEYSKTCFISSVKHTQSENGNKDHIDESGE
360 370 380 390 400 410
490 500 510 520 530 540
pF1KB8 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEEEAGLENSSEISADEWSRGNILKNSVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMN
420 430 440 450 460 470
550 560 570 580 590 600
pF1KB8 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNEDSCNKKSNVIDNKSGKVTAYDLLSNRVIKKPMSASALFVQDHRPQFLIENPKTSLED
480 490 500 510 520 530
610 620 630 640 650 660
pF1KB8 ATLQIEELWKTLSEEEKLKYEEKATKDLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATLQIEELWKTLSEEEKLKYEEKATKDLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAW
540 550 560 570 580 590
670 680 690 700 710 720
pF1KB8 NLAQKHKLKTSLSNQPKLDELLQSQIEKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLAQKHKLKTSLSNQPKLDELLQSQIEKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEE
600 610 620 630 640 650
730 740 750 760 770 780
pF1KB8 KDEPCLIHNLRFPDAWLMTSKTEVMLLNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDEPCLIHNLRFPDAWLMTSKTEVMLLNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTE
660 670 680 690 700 710
790 800 810 820 830 840
pF1KB8 SLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTANGFKIKLIPGVSITENYLEIEGMAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLFNGSHYLDVLYKMTADDQRYSGSTYLSDPRLTANGFKIKLIPGVSITENYLEIEGMAN
720 730 740 750 760 770
850 860 870 880 890 900
pF1KB8 CLPFYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLPFYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDI
780 790 800 810 820 830
910 920 930
pF1KB8 IYRMKHQFGNEIKECVHGRPFFHHLTYLPETT
::::::::::::::::::::::::::::::::
XP_016 IYRMKHQFGNEIKECVHGRPFFHHLTYLPETT
840 850 860 870
>>NP_001276337 (OMIM: 120435,600258) PMS1 protein homolo (756 aa)
initn: 4962 init1: 4962 opt: 4962 Z-score: 4069.1 bits: 763.9 E(85289): 0
Smith-Waterman score: 4962; 100.0% identity (100.0% similar) in 756 aa overlap (177-932:1-756)
150 160 170 180 190 200
pF1KB8 RLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFGILKPDLRIVFVHNKAVIWQKSRVSDH
::::::::::::::::::::::::::::::
NP_001 MSFGILKPDLRIVFVHNKAVIWQKSRVSDH
10 20 30
210 220 230 240 250 260
pF1KB8 KMALMSVLGTAVMNNMESFQYHSEESQIYLSGFLPKCDADHSFTSLSTPERSFIFINSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMALMSVLGTAVMNNMESFQYHSEESQIYLSGFLPKCDADHSFTSLSTPERSFIFINSRP
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB8 VHQKDILKLIRHHYNLKCLKESTRLYPVFFLKIDVPTADVDVNLTPDKSQVLLQNKESVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHQKDILKLIRHHYNLKCLKESTRLYPVFFLKIDVPTADVDVNLTPDKSQVLLQNKESVL
100 110 120 130 140 150
330 340 350 360 370 380
pF1KB8 IALENLMTTCYGPLPSTNSYENNKTDVSAADIVLSKTAETDVLFNKVESSGKNYSNVDTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IALENLMTTCYGPLPSTNSYENNKTDVSAADIVLSKTAETDVLFNKVESSGKNYSNVDTS
160 170 180 190 200 210
390 400 410 420 430 440
pF1KB8 VIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGHCSSEISNIDKNTKNAFQDISMSNVSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGHCSSEISNIDKNTKNAFQDISMSNVSW
220 230 240 250 260 270
450 460 470 480 490 500
pF1KB8 ENSQTEYSKTCFISSVKHTQSENGNKDHIDESGENEEEAGLENSSEISADEWSRGNILKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENSQTEYSKTCFISSVKHTQSENGNKDHIDESGENEEEAGLENSSEISADEWSRGNILKN
280 290 300 310 320 330
510 520 530 540 550 560
pF1KB8 SVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMNLNEDSCNKKSNVIDNKSGKVTAYDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMNLNEDSCNKKSNVIDNKSGKVTAYDLL
340 350 360 370 380 390
570 580 590 600 610 620
pF1KB8 SNRVIKKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEKLKYEEKATK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNRVIKKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEKLKYEEKATK
400 410 420 430 440 450
630 640 650 660 670 680
pF1KB8 DLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAWNLAQKHKLKTSLSNQPKLDELLQSQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAWNLAQKHKLKTSLSNQPKLDELLQSQI
460 470 480 490 500 510
690 700 710 720 730 740
pF1KB8 EKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEEKDEPCLIHNLRFPDAWLMTSKTEVML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEEKDEPCLIHNLRFPDAWLMTSKTEVML
520 530 540 550 560 570
750 760 770 780 790 800
pF1KB8 LNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTESLFNGSHYLDVLYKMTADDQRYSGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTESLFNGSHYLDVLYKMTADDQRYSGST
580 590 600 610 620 630
810 820 830 840 850 860
pF1KB8 YLSDPRLTANGFKIKLIPGVSITENYLEIEGMANCLPFYGVADLKEILNAILNRNAKEVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLSDPRLTANGFKIKLIPGVSITENYLEIEGMANCLPFYGVADLKEILNAILNRNAKEVY
640 650 660 670 680 690
870 880 890 900 910 920
pF1KB8 ECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDIIYRMKHQFGNEIKECVHGRPFFHHLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDIIYRMKHQFGNEIKECVHGRPFFHHLT
700 710 720 730 740 750
930
pF1KB8 YLPETT
::::::
NP_001 YLPETT
>>XP_011509658 (OMIM: 120435,600258) PREDICTED: PMS1 pro (756 aa)
initn: 4962 init1: 4962 opt: 4962 Z-score: 4069.1 bits: 763.9 E(85289): 0
Smith-Waterman score: 4962; 100.0% identity (100.0% similar) in 756 aa overlap (177-932:1-756)
150 160 170 180 190 200
pF1KB8 RLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFGILKPDLRIVFVHNKAVIWQKSRVSDH
::::::::::::::::::::::::::::::
XP_011 MSFGILKPDLRIVFVHNKAVIWQKSRVSDH
10 20 30
210 220 230 240 250 260
pF1KB8 KMALMSVLGTAVMNNMESFQYHSEESQIYLSGFLPKCDADHSFTSLSTPERSFIFINSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KMALMSVLGTAVMNNMESFQYHSEESQIYLSGFLPKCDADHSFTSLSTPERSFIFINSRP
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB8 VHQKDILKLIRHHYNLKCLKESTRLYPVFFLKIDVPTADVDVNLTPDKSQVLLQNKESVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHQKDILKLIRHHYNLKCLKESTRLYPVFFLKIDVPTADVDVNLTPDKSQVLLQNKESVL
100 110 120 130 140 150
330 340 350 360 370 380
pF1KB8 IALENLMTTCYGPLPSTNSYENNKTDVSAADIVLSKTAETDVLFNKVESSGKNYSNVDTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IALENLMTTCYGPLPSTNSYENNKTDVSAADIVLSKTAETDVLFNKVESSGKNYSNVDTS
160 170 180 190 200 210
390 400 410 420 430 440
pF1KB8 VIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGHCSSEISNIDKNTKNAFQDISMSNVSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGHCSSEISNIDKNTKNAFQDISMSNVSW
220 230 240 250 260 270
450 460 470 480 490 500
pF1KB8 ENSQTEYSKTCFISSVKHTQSENGNKDHIDESGENEEEAGLENSSEISADEWSRGNILKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENSQTEYSKTCFISSVKHTQSENGNKDHIDESGENEEEAGLENSSEISADEWSRGNILKN
280 290 300 310 320 330
510 520 530 540 550 560
pF1KB8 SVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMNLNEDSCNKKSNVIDNKSGKVTAYDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMNLNEDSCNKKSNVIDNKSGKVTAYDLL
340 350 360 370 380 390
570 580 590 600 610 620
pF1KB8 SNRVIKKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEKLKYEEKATK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNRVIKKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEKLKYEEKATK
400 410 420 430 440 450
630 640 650 660 670 680
pF1KB8 DLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAWNLAQKHKLKTSLSNQPKLDELLQSQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAWNLAQKHKLKTSLSNQPKLDELLQSQI
460 470 480 490 500 510
690 700 710 720 730 740
pF1KB8 EKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEEKDEPCLIHNLRFPDAWLMTSKTEVML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEEKDEPCLIHNLRFPDAWLMTSKTEVML
520 530 540 550 560 570
750 760 770 780 790 800
pF1KB8 LNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTESLFNGSHYLDVLYKMTADDQRYSGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTESLFNGSHYLDVLYKMTADDQRYSGST
580 590 600 610 620 630
810 820 830 840 850 860
pF1KB8 YLSDPRLTANGFKIKLIPGVSITENYLEIEGMANCLPFYGVADLKEILNAILNRNAKEVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLSDPRLTANGFKIKLIPGVSITENYLEIEGMANCLPFYGVADLKEILNAILNRNAKEVY
640 650 660 670 680 690
870 880 890 900 910 920
pF1KB8 ECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDIIYRMKHQFGNEIKECVHGRPFFHHLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDIIYRMKHQFGNEIKECVHGRPFFHHLT
700 710 720 730 740 750
930
pF1KB8 YLPETT
::::::
XP_011 YLPETT
>>NP_001276338 (OMIM: 120435,600258) PMS1 protein homolo (756 aa)
initn: 4962 init1: 4962 opt: 4962 Z-score: 4069.1 bits: 763.9 E(85289): 0
Smith-Waterman score: 4962; 100.0% identity (100.0% similar) in 756 aa overlap (177-932:1-756)
150 160 170 180 190 200
pF1KB8 RLFKNLPVRKQFYSTAKKCKDEIKKIQDLLMSFGILKPDLRIVFVHNKAVIWQKSRVSDH
::::::::::::::::::::::::::::::
NP_001 MSFGILKPDLRIVFVHNKAVIWQKSRVSDH
10 20 30
210 220 230 240 250 260
pF1KB8 KMALMSVLGTAVMNNMESFQYHSEESQIYLSGFLPKCDADHSFTSLSTPERSFIFINSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KMALMSVLGTAVMNNMESFQYHSEESQIYLSGFLPKCDADHSFTSLSTPERSFIFINSRP
40 50 60 70 80 90
270 280 290 300 310 320
pF1KB8 VHQKDILKLIRHHYNLKCLKESTRLYPVFFLKIDVPTADVDVNLTPDKSQVLLQNKESVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHQKDILKLIRHHYNLKCLKESTRLYPVFFLKIDVPTADVDVNLTPDKSQVLLQNKESVL
100 110 120 130 140 150
330 340 350 360 370 380
pF1KB8 IALENLMTTCYGPLPSTNSYENNKTDVSAADIVLSKTAETDVLFNKVESSGKNYSNVDTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IALENLMTTCYGPLPSTNSYENNKTDVSAADIVLSKTAETDVLFNKVESSGKNYSNVDTS
160 170 180 190 200 210
390 400 410 420 430 440
pF1KB8 VIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGHCSSEISNIDKNTKNAFQDISMSNVSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIPFQNDMHNDESGKNTDDCLNHQISIGDFGYGHCSSEISNIDKNTKNAFQDISMSNVSW
220 230 240 250 260 270
450 460 470 480 490 500
pF1KB8 ENSQTEYSKTCFISSVKHTQSENGNKDHIDESGENEEEAGLENSSEISADEWSRGNILKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENSQTEYSKTCFISSVKHTQSENGNKDHIDESGENEEEAGLENSSEISADEWSRGNILKN
280 290 300 310 320 330
510 520 530 540 550 560
pF1KB8 SVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMNLNEDSCNKKSNVIDNKSGKVTAYDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVGENIEPVKILVPEKSLPCKVSNNNYPIPEQMNLNEDSCNKKSNVIDNKSGKVTAYDLL
340 350 360 370 380 390
570 580 590 600 610 620
pF1KB8 SNRVIKKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEKLKYEEKATK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNRVIKKPMSASALFVQDHRPQFLIENPKTSLEDATLQIEELWKTLSEEEKLKYEEKATK
400 410 420 430 440 450
630 640 650 660 670 680
pF1KB8 DLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAWNLAQKHKLKTSLSNQPKLDELLQSQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLERYNSQMKRAIEQESQMSLKDGRKKIKPTSAWNLAQKHKLKTSLSNQPKLDELLQSQI
460 470 480 490 500 510
690 700 710 720 730 740
pF1KB8 EKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEEKDEPCLIHNLRFPDAWLMTSKTEVML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKRRSQNIKMVQIPFSMKNLKINFKKQNKVDLEEKDEPCLIHNLRFPDAWLMTSKTEVML
520 530 540 550 560 570
750 760 770 780 790 800
pF1KB8 LNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTESLFNGSHYLDVLYKMTADDQRYSGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNPYRVEEALLFKRLLENHKLPAEPLEKPIMLTESLFNGSHYLDVLYKMTADDQRYSGST
580 590 600 610 620 630
810 820 830 840 850 860
pF1KB8 YLSDPRLTANGFKIKLIPGVSITENYLEIEGMANCLPFYGVADLKEILNAILNRNAKEVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YLSDPRLTANGFKIKLIPGVSITENYLEIEGMANCLPFYGVADLKEILNAILNRNAKEVY
640 650 660 670 680 690
870 880 890 900 910 920
pF1KB8 ECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDIIYRMKHQFGNEIKECVHGRPFFHHLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDIIYRMKHQFGNEIKECVHGRPFFHHLT
700 710 720 730 740 750
930
pF1KB8 YLPETT
::::::
NP_001 YLPETT
932 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 18:09:56 2016 done: Sun Nov 6 18:09:58 2016
Total Scan time: 10.810 Total Display time: 0.300
Function used was FASTA [36.3.4 Apr, 2011]