FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8507, 941 aa 1>>>pF1KB8507 941 - 941 aa - 941 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3766+/-0.00118; mu= 16.4511+/- 0.070 mean_var=107.1510+/-21.845, 0's: 0 Z-trim(105.6): 47 B-trim: 534 in 1/50 Lambda= 0.123901 statistics sampled from 8478 (8504) to 8478 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.624), E-opt: 0.2 (0.261), width: 16 Scan time: 4.350 The best scores are: opt bits E(32554) CCDS73404.1 VPS11 gene_id:55823|Hs108|chr11 ( 941) 6338 1144.7 0 CCDS76485.1 VPS11 gene_id:55823|Hs108|chr11 ( 931) 5904 1067.1 0 >>CCDS73404.1 VPS11 gene_id:55823|Hs108|chr11 (941 aa) initn: 6338 init1: 6338 opt: 6338 Z-score: 6125.3 bits: 1144.7 E(32554): 0 Smith-Waterman score: 6338; 99.9% identity (100.0% similar) in 941 aa overlap (1-941:1-941) 10 20 30 40 50 60 pF1KB8 MAAYLQWRRFVFFDKELVKEPLSNDGAAPGATPASGSAASKFLCLPPGITVCDSGRGSLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 MAAYLQWRRFVFFDKELVKEPLSNDGAAPGATPASGSAASKFLCLPPGITVCDSGRGSLV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FGDMEGQIWFLPRSLQLTGFQAYKLRVTHLYQLKQHNILASVGEDEEGINPLVKIWNLEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 FGDMEGQIWFLPRSLQLTGFQAYKLRVTHLYQLKQHNILASVGEDEEGINPLVKIWNLEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RDGGNPLCTRIFPAIPGTEPTVVSCLTVHENLNFMAIGFTDGSVTLNKGDITRDRHSKTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 RDGGNPLCTRIFPAIPGTEPTVVSCLTVHENLNFMAIGFTDGSVTLNKGDITRDRHSKTQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ILHKGNYPVTGLAFRQAGKTTHLFVVTTENVQSYIVSGKDYPRVELDTHGCGLRCSALSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 ILHKGNYPVTGLAFRQAGKTTHLFVVTTENVQSYIVSGKDYPRVELDTHGCGLRCSALSD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 PSQDLQFIVAGDECVYLYQPDERGPCFAFEGHKLIAHWFRGYLIIVSRDRKVSPKSEFTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 PSQDLQFIVAGDECVYLYQPDERGPCFAFEGHKLIAHWFRGYLIIVSRDRKVSPKSEFTS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 RDSQSSDKQILNIYDLCNKFIAYSTVFEDVVDVLAEWGSLYVLTRDGRVHALQEKDTQTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 RDSQSSDKQILNIYDLCNKFIAYSTVFEDVVDVLAEWGSLYVLTRDGRVHALQEKDTQTK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 LEMLFKKNLFEMAINLAKSQHLDSDGLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 LEMLFKKNLFEMAINLAKSQHLDSDGLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEP 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 SYVIRKFLDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKKKSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 SYVIRKFLDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKKKSES 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 EVHFDVETAIKVLRQAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 EVHFDVETAIKVLRQAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQ 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 AESNMKRYGKILMHHIPEQTTQLLKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 AESNMKRYGKILMHHIPEQTTQLLKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 PRELKAFLEHMSEVQPDSPQGIYDTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGRFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 PRELKAFLEHMSEVQPDSPQGIYDTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGRFC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 DVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVISVCERHGEQDPSLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 DVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVISVCERHGEQDPSLW 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 EQALSYFARKEEDCKEYVAAVLKHIENKNLMPPLLVVQTLAHNSTATLSVIRDYLVQKLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 EQALSYFARKEEDCKEYVAAVLKHIENKNLMPPLLVVQTLAHNSTATLSVIRDYLVQKLQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB8 KQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 KQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGH 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB8 SFHQHCFESYSESDADCPTCLPENRKVMDMIRAQEQKRDLHDQFQHQLRCSNDSFSVIAD ::::::::::::::::::::::::::::::::::::::::::::::::.::::::::::: CCDS73 SFHQHCFESYSESDADCPTCLPENRKVMDMIRAQEQKRDLHDQFQHQLKCSNDSFSVIAD 850 860 870 880 890 900 910 920 930 940 pF1KB8 YFGRGVFNKLTLLTDPPTARLTSSLEAGLQRDLLMHSRRGT ::::::::::::::::::::::::::::::::::::::::: CCDS73 YFGRGVFNKLTLLTDPPTARLTSSLEAGLQRDLLMHSRRGT 910 920 930 940 >>CCDS76485.1 VPS11 gene_id:55823|Hs108|chr11 (931 aa) initn: 5904 init1: 5904 opt: 5904 Z-score: 5706.0 bits: 1067.1 E(32554): 0 Smith-Waterman score: 5904; 99.9% identity (100.0% similar) in 878 aa overlap (64-941:54-931) 40 50 60 70 80 90 pF1KB8 ASGSAASKFLCLPPGITVCDSGRGSLVFGDMEGQIWFLPRSLQLTGFQAYKLRVTHLYQL :::::::::::::::::::::::::::::: CCDS76 LWSTGRKKEVHLLTCYQLSNPGRLLDYPAHMEGQIWFLPRSLQLTGFQAYKLRVTHLYQL 30 40 50 60 70 80 100 110 120 130 140 150 pF1KB8 KQHNILASVGEDEEGINPLVKIWNLEKRDGGNPLCTRIFPAIPGTEPTVVSCLTVHENLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 KQHNILASVGEDEEGINPLVKIWNLEKRDGGNPLCTRIFPAIPGTEPTVVSCLTVHENLN 90 100 110 120 130 140 160 170 180 190 200 210 pF1KB8 FMAIGFTDGSVTLNKGDITRDRHSKTQILHKGNYPVTGLAFRQAGKTTHLFVVTTENVQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 FMAIGFTDGSVTLNKGDITRDRHSKTQILHKGNYPVTGLAFRQAGKTTHLFVVTTENVQS 150 160 170 180 190 200 220 230 240 250 260 270 pF1KB8 YIVSGKDYPRVELDTHGCGLRCSALSDPSQDLQFIVAGDECVYLYQPDERGPCFAFEGHK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 YIVSGKDYPRVELDTHGCGLRCSALSDPSQDLQFIVAGDECVYLYQPDERGPCFAFEGHK 210 220 230 240 250 260 280 290 300 310 320 330 pF1KB8 LIAHWFRGYLIIVSRDRKVSPKSEFTSRDSQSSDKQILNIYDLCNKFIAYSTVFEDVVDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 LIAHWFRGYLIIVSRDRKVSPKSEFTSRDSQSSDKQILNIYDLCNKFIAYSTVFEDVVDV 270 280 290 300 310 320 340 350 360 370 380 390 pF1KB8 LAEWGSLYVLTRDGRVHALQEKDTQTKLEMLFKKNLFEMAINLAKSQHLDSDGLAQIFMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 LAEWGSLYVLTRDGRVHALQEKDTQTKLEMLFKKNLFEMAINLAKSQHLDSDGLAQIFMQ 330 340 350 360 370 380 400 410 420 430 440 450 pF1KB8 YGDHLYSKGNHDGAVQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQTLHRQSLANADH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 YGDHLYSKGNHDGAVQQYIRTIGKLEPSYVIRKFLDAQRIHNLTAYLQTLHRQSLANADH 390 400 410 420 430 440 460 470 480 490 500 510 pF1KB8 TTLLLNCYTKLKDSSKLEEFIKKKSESEVHFDVETAIKVLRQAGYYSHALYLAENHAHHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 TTLLLNCYTKLKDSSKLEEFIKKKSESEVHFDVETAIKVLRQAGYYSHALYLAENHAHHE 450 460 470 480 490 500 520 530 540 550 560 570 pF1KB8 WYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMHHIPEQTTQLLKGLCTDYRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 WYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMHHIPEQTTQLLKGLCTDYRP 510 520 530 540 550 560 580 590 600 610 620 630 pF1KB8 SLEGRSDREAPGCRANSEEFIPIFANNPRELKAFLEHMSEVQPDSPQGIYDTLLELRLQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 SLEGRSDREAPGCRANSEEFIPIFANNPRELKAFLEHMSEVQPDSPQGIYDTLLELRLQN 570 580 590 600 610 620 640 650 660 670 680 690 pF1KB8 WAHEKDPQVKEKLHAEAISLLKSGRFCDVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 WAHEKDPQVKEKLHAEAISLLKSGRFCDVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIM 630 640 650 660 670 680 700 710 720 730 740 750 pF1KB8 HYHMQHEQYRQVISVCERHGEQDPSLWEQALSYFARKEEDCKEYVAAVLKHIENKNLMPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 HYHMQHEQYRQVISVCERHGEQDPSLWEQALSYFARKEEDCKEYVAAVLKHIENKNLMPP 690 700 710 720 730 740 760 770 780 790 800 810 pF1KB8 LLVVQTLAHNSTATLSVIRDYLVQKLQKQSQQIAQDELRVRRYREETTRIRQEIQELKAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 LLVVQTLAHNSTATLSVIRDYLVQKLQKQSQQIAQDELRVRRYREETTRIRQEIQELKAS 750 760 770 780 790 800 820 830 840 850 860 870 pF1KB8 PKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKVMDMIRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS76 PKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKVMDMIRA 810 820 830 840 850 860 880 890 900 910 920 930 pF1KB8 QEQKRDLHDQFQHQLRCSNDSFSVIADYFGRGVFNKLTLLTDPPTARLTSSLEAGLQRDL :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: CCDS76 QEQKRDLHDQFQHQLKCSNDSFSVIADYFGRGVFNKLTLLTDPPTARLTSSLEAGLQRDL 870 880 890 900 910 920 940 pF1KB8 LMHSRRGT :::::::: CCDS76 LMHSRRGT 930 941 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:06:58 2016 done: Sat Nov 5 16:06:59 2016 Total Scan time: 4.350 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]