FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8508, 866 aa 1>>>pF1KB8508 866 - 866 aa - 866 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.0127+/-0.000491; mu= -5.4344+/- 0.030 mean_var=334.1074+/-69.714, 0's: 0 Z-trim(118.2): 76 B-trim: 534 in 1/54 Lambda= 0.070167 statistics sampled from 30872 (30952) to 30872 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.689), E-opt: 0.2 (0.363), width: 16 Scan time: 15.110 The best scores are: opt bits E(85289) NP_000499 (OMIM: 105200,134820,202400,616004) fibr ( 866) 5919 614.0 9.4e-175 NP_068657 (OMIM: 105200,134820,202400,616004) fibr ( 644) 4275 447.5 9.4e-125 NP_000500 (OMIM: 134850,202400,616004) fibrinogen ( 437) 705 86.0 4.3e-16 NP_068656 (OMIM: 134850,202400,616004) fibrinogen ( 453) 705 86.0 4.4e-16 XP_016868722 (OMIM: 605776) PREDICTED: fibrinogen- ( 282) 684 83.7 1.3e-15 NP_963846 (OMIM: 605776) fibrinogen-like protein 1 ( 312) 684 83.7 1.4e-15 NP_963847 (OMIM: 605776) fibrinogen-like protein 1 ( 312) 684 83.7 1.4e-15 NP_004458 (OMIM: 605776) fibrinogen-like protein 1 ( 312) 684 83.7 1.4e-15 NP_671736 (OMIM: 605776) fibrinogen-like protein 1 ( 312) 684 83.7 1.4e-15 XP_016868721 (OMIM: 605776) PREDICTED: fibrinogen- ( 312) 684 83.7 1.4e-15 NP_006673 (OMIM: 605351) fibroleukin precursor [Ho ( 439) 580 73.3 2.8e-12 NP_116232 (OMIM: 613357) fibrinogen C domain-conta ( 461) 536 68.9 6.3e-11 NP_001138578 (OMIM: 613357) fibrinogen C domain-co ( 461) 536 68.9 6.3e-11 NP_002395 (OMIM: 600596) microfibril-associated gl ( 255) 501 65.1 4.6e-10 NP_001185624 (OMIM: 600596) microfibril-associated ( 279) 501 65.2 5e-10 NP_001300980 (OMIM: 601667) angiopoietin-1 isoform ( 298) 466 61.6 6.1e-09 NP_001137 (OMIM: 601667) angiopoietin-1 isoform 1 ( 498) 466 61.8 9.1e-09 NP_001186788 (OMIM: 601667) angiopoietin-1 isoform ( 497) 464 61.6 1e-08 XP_005272541 (OMIM: 605910,615881) PREDICTED: angi ( 424) 456 60.7 1.6e-08 XP_016868807 (OMIM: 601922) PREDICTED: angiopoieti ( 443) 441 59.2 4.8e-08 NP_001112359 (OMIM: 601922) angiopoietin-2 isoform ( 495) 441 59.3 5.2e-08 NP_001112360 (OMIM: 601922) angiopoietin-2 isoform ( 444) 438 58.9 5.9e-08 XP_011527541 (OMIM: 603705) PREDICTED: angiopoieti ( 451) 437 58.8 6.4e-08 NP_001138 (OMIM: 601922) angiopoietin-2 isoform a ( 496) 438 59.0 6.5e-08 NP_057069 (OMIM: 603705) angiopoietin-4 isoform 1 ( 503) 437 58.9 7e-08 NP_835228 (OMIM: 607666) angiopoietin-related prot ( 388) 420 57.1 1.9e-07 NP_775628 (OMIM: 604973,613860) ficolin-3 isoform ( 288) 404 55.4 4.6e-07 NP_003656 (OMIM: 604973,613860) ficolin-3 isoform ( 299) 403 55.3 5.1e-07 NP_001309738 (OMIM: 603705) angiopoietin-4 isoform ( 410) 392 54.3 1.4e-06 NP_115859 (OMIM: 600985,606408,615963) tenascin-X ( 673) 394 54.6 1.8e-06 XP_005272542 (OMIM: 605910,615881) PREDICTED: angi ( 386) 378 52.8 3.6e-06 NP_055310 (OMIM: 604774,605019) angiopoietin-relat ( 460) 373 52.4 5.8e-06 NP_061978 (OMIM: 600985,606408,615963) tenascin-X (4242) 394 55.2 7.4e-06 XP_011541037 (OMIM: 607666) PREDICTED: angiopoieti ( 323) 357 50.6 1.4e-05 NP_001315564 (OMIM: 601995) tenascin-R isoform 2 [ (1025) 366 51.9 1.8e-05 XP_011508251 (OMIM: 601995) PREDICTED: tenascin-R (1199) 366 52.0 2e-05 NP_647475 (OMIM: 605910,615881) angiopoietin-relat ( 406) 353 50.3 2.2e-05 XP_016857708 (OMIM: 601995) PREDICTED: tenascin-R (1358) 366 52.0 2.2e-05 XP_016857707 (OMIM: 601995) PREDICTED: tenascin-R (1358) 366 52.0 2.2e-05 NP_003276 (OMIM: 601995) tenascin-R isoform 1 prec (1358) 366 52.0 2.2e-05 XP_006717078 (OMIM: 601624) PREDICTED: ficolin-2 i ( 264) 323 47.1 0.00013 NP_056652 (OMIM: 601624) ficolin-2 isoform b precu ( 275) 323 47.1 0.00013 XP_011516694 (OMIM: 601624) PREDICTED: ficolin-2 i ( 302) 323 47.2 0.00014 NP_004099 (OMIM: 601624) ficolin-2 isoform a precu ( 313) 323 47.2 0.00014 NP_001994 (OMIM: 601252) ficolin-1 precursor [Homo ( 326) 319 46.8 0.0002 XP_005245634 (OMIM: 603874) PREDICTED: angiopoieti ( 491) 310 46.0 0.00051 NP_004664 (OMIM: 603874) angiopoietin-related prot ( 491) 310 46.0 0.00051 NP_036230 (OMIM: 605001) angiopoietin-related prot ( 493) 308 45.8 0.00059 NP_114123 (OMIM: 609336) angiopoietin-related prot ( 470) 286 43.6 0.0027 NP_001308340 (OMIM: 609336) angiopoietin-related p ( 470) 286 43.6 0.0027 >>NP_000499 (OMIM: 105200,134820,202400,616004) fibrinog (866 aa) initn: 5919 init1: 5919 opt: 5919 Z-score: 3258.3 bits: 614.0 E(85289): 9.4e-175 Smith-Waterman score: 5919; 100.0% identity (100.0% similar) in 866 aa overlap (1-866:1-866) 10 20 30 40 50 60 pF1KB8 MFSMRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MFSMRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 NYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 NNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 NNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 RGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFKSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 RGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFKSQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 GPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 NPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 NPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 SPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 EVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 EVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 VSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 VSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 YKMADEAGSEADHEGTHSTKRGHAKSRPVRDCDDVLQTHPSGTQSGIFNIKLPGSSKIFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 YKMADEAGSEADHEGTHSTKRGHAKSRPVRDCDDVLQTHPSGTQSGIFNIKLPGSSKIFS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 VYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 VYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 GSVLRVELEDWAGNEAYAEYHFRVGSEAEGYALQVSSYEGTAGDALIEGSVEEGAEYTSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GSVLRVELEDWAGNEAYAEYHFRVGSEAEGYALQVSSYEGTAGDALIEGSVEEGAEYTSH 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB8 NNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRNNSPYEIENG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 NNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRNNSPYEIENG 790 800 810 820 830 840 850 860 pF1KB8 VVWVSFRGADYSLRAVRMKIRPLVTQ :::::::::::::::::::::::::: NP_000 VVWVSFRGADYSLRAVRMKIRPLVTQ 850 860 >>NP_068657 (OMIM: 105200,134820,202400,616004) fibrinog (644 aa) initn: 4269 init1: 4269 opt: 4275 Z-score: 2360.7 bits: 447.5 E(85289): 9.4e-125 Smith-Waterman score: 4275; 98.3% identity (98.6% similar) in 645 aa overlap (1-645:1-641) 10 20 30 40 50 60 pF1KB8 MFSMRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 MFSMRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 NYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 NNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 NNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 RGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFKSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 RGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFKSQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 LQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 GPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 GPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTW 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 NPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 NPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 SPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 SPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 EVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 EVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEF 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 VSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 VSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 YKMADEAGSEADHEGTHSTKRGHAKSRPVRDCDDVLQTHPSGTQSGIFNIKLPGSSKIFS :::::::::::::::::::::::::::::: ..: : : : NP_068 YKMADEAGSEADHEGTHSTKRGHAKSRPVRG----IHTSPLGKPSLSP 610 620 630 640 670 680 690 700 710 720 pF1KB8 VYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQR >>NP_000500 (OMIM: 134850,202400,616004) fibrinogen gamm (437 aa) initn: 697 init1: 266 opt: 705 Z-score: 409.9 bits: 86.0 E(85289): 4.3e-16 Smith-Waterman score: 705; 42.6% identity (71.9% similar) in 242 aa overlap (630-863:177-415) 600 610 620 630 640 650 pF1KB8 SYKMADEAGSEADHEGTHSTKRGHAKSRPVRDCDDVLQTHPSGTQSGIFNIKLPGSSKIF .::.:. .. .. :::.. :: ... : NP_000 IVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDI--ANKGAKQSGLYFIKPLKANQQF 150 160 170 180 190 200 660 670 680 690 700 710 pF1KB8 SVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQ :::. . : .:: ..:.:.:::..:...: .::.::: :. : ::::::. .::.. NP_000 LVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLIST 210 220 230 240 250 260 720 730 740 750 760 770 pF1KB8 RGSV---LRVELEDWAGNEAYAEY-HFRVGSEAEGYALQVSSYEG-TAGDALIE---GSV .... :::::::: : . :.: :.:: ::. : : . . : ::::. :. NP_000 QSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDD 270 280 290 300 310 320 780 790 800 810 820 830 pF1KB8 EEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRN .::::.:::::.: : :..: :::: :.:::.:.:.:..:::.:: ::.:. . NP_000 PSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYS-KA 330 340 350 360 370 380 840 850 860 pF1KB8 NSPYEIENGVVWVSFRGADYSLRAVRMKIRPLVTQ ..: .::..:.... ::.. . ::: :. NP_000 STPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTIGEGQQHHLGGAKQAGDV 390 400 410 420 430 >>NP_068656 (OMIM: 134850,202400,616004) fibrinogen gamm (453 aa) initn: 697 init1: 266 opt: 705 Z-score: 409.7 bits: 86.0 E(85289): 4.4e-16 Smith-Waterman score: 705; 42.6% identity (71.9% similar) in 242 aa overlap (630-863:177-415) 600 610 620 630 640 650 pF1KB8 SYKMADEAGSEADHEGTHSTKRGHAKSRPVRDCDDVLQTHPSGTQSGIFNIKLPGSSKIF .::.:. .. .. :::.. :: ... : NP_068 IVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDI--ANKGAKQSGLYFIKPLKANQQF 150 160 170 180 190 200 660 670 680 690 700 710 pF1KB8 SVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQ :::. . : .:: ..:.:.:::..:...: .::.::: :. : ::::::. .::.. NP_068 LVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLIST 210 220 230 240 250 260 720 730 740 750 760 770 pF1KB8 RGSV---LRVELEDWAGNEAYAEY-HFRVGSEAEGYALQVSSYEG-TAGDALIE---GSV .... :::::::: : . :.: :.:: ::. : : . . : ::::. :. NP_068 QSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDD 270 280 290 300 310 320 780 790 800 810 820 830 pF1KB8 EEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRN .::::.:::::.: : :..: :::: :.:::.:.:.:..:::.:: ::.:. . NP_068 PSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYS-KA 330 340 350 360 370 380 840 850 860 pF1KB8 NSPYEIENGVVWVSFRGADYSLRAVRMKIRPLVTQ ..: .::..:.... ::.. . ::: :. NP_068 STPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTIGEGQQHHLGGAKQVRPEHPAETE 390 400 410 420 430 440 NP_068 YDSLYPEDDL 450 >>XP_016868722 (OMIM: 605776) PREDICTED: fibrinogen-like (282 aa) initn: 630 init1: 297 opt: 684 Z-score: 401.1 bits: 83.7 E(85289): 1.3e-15 Smith-Waterman score: 685; 44.1% identity (70.1% similar) in 254 aa overlap (614-862:35-274) 590 600 610 620 630 640 pF1KB8 TSSTSYNRGDSTFESKSYKMADEAGSEADHEGTHSTKRGHAKSRPVRDCDDVLQTHPSGT .: ..: ...: ::..... .: XP_016 AQVRLLETRVKQQQVKIKQLLQENEVQFLDKGDENTVIDLGSKRQYADCSEIFN---DGY 10 20 30 40 50 60 650 660 670 680 690 700 pF1KB8 Q-SGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDE . ::...:: : ::::::. .. ::: .::.: ::: :::: :.::. :::.. .. XP_016 KLSGFYKIKPLQSPAEFSVYCDM-SDGGGWTVIQRRSDGSENFNRGWKDYENGFGNFVQK 70 80 90 100 110 120 710 720 730 740 750 760 pF1KB8 GEGEFWLGNDYLHLLT-QRGSVLRVELEDWAGNEAYAEY-HFRVGSEAEGYALQVSSYEG .::.:::: ::.:: :. .:...: :. : ::.: .:.::.: . : :... : : XP_016 -HGEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSG 130 140 150 160 170 770 780 790 800 810 820 pF1KB8 TAGDALIEGSVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGI ::::.: . : ..::. :.:::.::: :..: :::: .:::.: :..:::::. XP_016 TAGDSLAGNFHPEVQWWASHQRMKFSTWDRDHDNYEGNCAEEDQSGWWFNRCHSANLNGV 180 190 200 210 220 230 830 840 850 860 pF1KB8 YYPGGSYDPRNNSPY--EIENGVVWVSFRGADYSLRAVRMKIRPLVTQ :: : :: . .::.:: ...: :::..: ::::: XP_016 YYSG---------PYTAKTDNGIVWYTWHGWWYSLKSVVMKIRPNDFIPNVI 240 250 260 270 280 >>NP_963846 (OMIM: 605776) fibrinogen-like protein 1 pre (312 aa) initn: 630 init1: 297 opt: 684 Z-score: 400.5 bits: 83.7 E(85289): 1.4e-15 Smith-Waterman score: 685; 44.1% identity (70.1% similar) in 254 aa overlap (614-862:65-304) 590 600 610 620 630 640 pF1KB8 TSSTSYNRGDSTFESKSYKMADEAGSEADHEGTHSTKRGHAKSRPVRDCDDVLQTHPSGT .: ..: ...: ::..... .: NP_963 AQVRLLETRVKQQQVKIKQLLQENEVQFLDKGDENTVIDLGSKRQYADCSEIFN---DGY 40 50 60 70 80 90 650 660 670 680 690 700 pF1KB8 Q-SGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDE . ::...:: : ::::::. .. ::: .::.: ::: :::: :.::. :::.. .. NP_963 KLSGFYKIKPLQSPAEFSVYCDM-SDGGGWTVIQRRSDGSENFNRGWKDYENGFGNFVQK 100 110 120 130 140 150 710 720 730 740 750 760 pF1KB8 GEGEFWLGNDYLHLLT-QRGSVLRVELEDWAGNEAYAEY-HFRVGSEAEGYALQVSSYEG .::.:::: ::.:: :. .:...: :. : ::.: .:.::.: . : :... : : NP_963 -HGEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSG 160 170 180 190 200 770 780 790 800 810 820 pF1KB8 TAGDALIEGSVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGI ::::.: . : ..::. :.:::.::: :..: :::: .:::.: :..:::::. NP_963 TAGDSLAGNFHPEVQWWASHQRMKFSTWDRDHDNYEGNCAEEDQSGWWFNRCHSANLNGV 210 220 230 240 250 260 830 840 850 860 pF1KB8 YYPGGSYDPRNNSPY--EIENGVVWVSFRGADYSLRAVRMKIRPLVTQ :: : :: . .::.:: ...: :::..: ::::: NP_963 YYSG---------PYTAKTDNGIVWYTWHGWWYSLKSVVMKIRPNDFIPNVI 270 280 290 300 310 >>NP_963847 (OMIM: 605776) fibrinogen-like protein 1 pre (312 aa) initn: 630 init1: 297 opt: 684 Z-score: 400.5 bits: 83.7 E(85289): 1.4e-15 Smith-Waterman score: 685; 44.1% identity (70.1% similar) in 254 aa overlap (614-862:65-304) 590 600 610 620 630 640 pF1KB8 TSSTSYNRGDSTFESKSYKMADEAGSEADHEGTHSTKRGHAKSRPVRDCDDVLQTHPSGT .: ..: ...: ::..... .: NP_963 AQVRLLETRVKQQQVKIKQLLQENEVQFLDKGDENTVIDLGSKRQYADCSEIFN---DGY 40 50 60 70 80 90 650 660 670 680 690 700 pF1KB8 Q-SGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDE . ::...:: : ::::::. .. ::: .::.: ::: :::: :.::. :::.. .. NP_963 KLSGFYKIKPLQSPAEFSVYCDM-SDGGGWTVIQRRSDGSENFNRGWKDYENGFGNFVQK 100 110 120 130 140 150 710 720 730 740 750 760 pF1KB8 GEGEFWLGNDYLHLLT-QRGSVLRVELEDWAGNEAYAEY-HFRVGSEAEGYALQVSSYEG .::.:::: ::.:: :. .:...: :. : ::.: .:.::.: . : :... : : NP_963 -HGEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSG 160 170 180 190 200 770 780 790 800 810 820 pF1KB8 TAGDALIEGSVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGI ::::.: . : ..::. :.:::.::: :..: :::: .:::.: :..:::::. NP_963 TAGDSLAGNFHPEVQWWASHQRMKFSTWDRDHDNYEGNCAEEDQSGWWFNRCHSANLNGV 210 220 230 240 250 260 830 840 850 860 pF1KB8 YYPGGSYDPRNNSPY--EIENGVVWVSFRGADYSLRAVRMKIRPLVTQ :: : :: . .::.:: ...: :::..: ::::: NP_963 YYSG---------PYTAKTDNGIVWYTWHGWWYSLKSVVMKIRPNDFIPNVI 270 280 290 300 310 >>NP_004458 (OMIM: 605776) fibrinogen-like protein 1 pre (312 aa) initn: 630 init1: 297 opt: 684 Z-score: 400.5 bits: 83.7 E(85289): 1.4e-15 Smith-Waterman score: 685; 44.1% identity (70.1% similar) in 254 aa overlap (614-862:65-304) 590 600 610 620 630 640 pF1KB8 TSSTSYNRGDSTFESKSYKMADEAGSEADHEGTHSTKRGHAKSRPVRDCDDVLQTHPSGT .: ..: ...: ::..... .: NP_004 AQVRLLETRVKQQQVKIKQLLQENEVQFLDKGDENTVIDLGSKRQYADCSEIFN---DGY 40 50 60 70 80 90 650 660 670 680 690 700 pF1KB8 Q-SGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDE . ::...:: : ::::::. .. ::: .::.: ::: :::: :.::. :::.. .. NP_004 KLSGFYKIKPLQSPAEFSVYCDM-SDGGGWTVIQRRSDGSENFNRGWKDYENGFGNFVQK 100 110 120 130 140 150 710 720 730 740 750 760 pF1KB8 GEGEFWLGNDYLHLLT-QRGSVLRVELEDWAGNEAYAEY-HFRVGSEAEGYALQVSSYEG .::.:::: ::.:: :. .:...: :. : ::.: .:.::.: . : :... : : NP_004 -HGEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSG 160 170 180 190 200 770 780 790 800 810 820 pF1KB8 TAGDALIEGSVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGI ::::.: . : ..::. :.:::.::: :..: :::: .:::.: :..:::::. NP_004 TAGDSLAGNFHPEVQWWASHQRMKFSTWDRDHDNYEGNCAEEDQSGWWFNRCHSANLNGV 210 220 230 240 250 260 830 840 850 860 pF1KB8 YYPGGSYDPRNNSPY--EIENGVVWVSFRGADYSLRAVRMKIRPLVTQ :: : :: . .::.:: ...: :::..: ::::: NP_004 YYSG---------PYTAKTDNGIVWYTWHGWWYSLKSVVMKIRPNDFIPNVI 270 280 290 300 310 >>NP_671736 (OMIM: 605776) fibrinogen-like protein 1 pre (312 aa) initn: 630 init1: 297 opt: 684 Z-score: 400.5 bits: 83.7 E(85289): 1.4e-15 Smith-Waterman score: 685; 44.1% identity (70.1% similar) in 254 aa overlap (614-862:65-304) 590 600 610 620 630 640 pF1KB8 TSSTSYNRGDSTFESKSYKMADEAGSEADHEGTHSTKRGHAKSRPVRDCDDVLQTHPSGT .: ..: ...: ::..... .: NP_671 AQVRLLETRVKQQQVKIKQLLQENEVQFLDKGDENTVIDLGSKRQYADCSEIFN---DGY 40 50 60 70 80 90 650 660 670 680 690 700 pF1KB8 Q-SGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDE . ::...:: : ::::::. .. ::: .::.: ::: :::: :.::. :::.. .. NP_671 KLSGFYKIKPLQSPAEFSVYCDM-SDGGGWTVIQRRSDGSENFNRGWKDYENGFGNFVQK 100 110 120 130 140 150 710 720 730 740 750 760 pF1KB8 GEGEFWLGNDYLHLLT-QRGSVLRVELEDWAGNEAYAEY-HFRVGSEAEGYALQVSSYEG .::.:::: ::.:: :. .:...: :. : ::.: .:.::.: . : :... : : NP_671 -HGEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSG 160 170 180 190 200 770 780 790 800 810 820 pF1KB8 TAGDALIEGSVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGI ::::.: . : ..::. :.:::.::: :..: :::: .:::.: :..:::::. NP_671 TAGDSLAGNFHPEVQWWASHQRMKFSTWDRDHDNYEGNCAEEDQSGWWFNRCHSANLNGV 210 220 230 240 250 260 830 840 850 860 pF1KB8 YYPGGSYDPRNNSPY--EIENGVVWVSFRGADYSLRAVRMKIRPLVTQ :: : :: . .::.:: ...: :::..: ::::: NP_671 YYSG---------PYTAKTDNGIVWYTWHGWWYSLKSVVMKIRPNDFIPNVI 270 280 290 300 310 >>XP_016868721 (OMIM: 605776) PREDICTED: fibrinogen-like (312 aa) initn: 630 init1: 297 opt: 684 Z-score: 400.5 bits: 83.7 E(85289): 1.4e-15 Smith-Waterman score: 685; 44.1% identity (70.1% similar) in 254 aa overlap (614-862:65-304) 590 600 610 620 630 640 pF1KB8 TSSTSYNRGDSTFESKSYKMADEAGSEADHEGTHSTKRGHAKSRPVRDCDDVLQTHPSGT .: ..: ...: ::..... .: XP_016 AQVRLLETRVKQQQVKIKQLLQENEVQFLDKGDENTVIDLGSKRQYADCSEIFN---DGY 40 50 60 70 80 90 650 660 670 680 690 700 pF1KB8 Q-SGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDE . ::...:: : ::::::. .. ::: .::.: ::: :::: :.::. :::.. .. XP_016 KLSGFYKIKPLQSPAEFSVYCDM-SDGGGWTVIQRRSDGSENFNRGWKDYENGFGNFVQK 100 110 120 130 140 150 710 720 730 740 750 760 pF1KB8 GEGEFWLGNDYLHLLT-QRGSVLRVELEDWAGNEAYAEY-HFRVGSEAEGYALQVSSYEG .::.:::: ::.:: :. .:...: :. : ::.: .:.::.: . : :... : : XP_016 -HGEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEYSG 160 170 180 190 200 770 780 790 800 810 820 pF1KB8 TAGDALIEGSVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGI ::::.: . : ..::. :.:::.::: :..: :::: .:::.: :..:::::. XP_016 TAGDSLAGNFHPEVQWWASHQRMKFSTWDRDHDNYEGNCAEEDQSGWWFNRCHSANLNGV 210 220 230 240 250 260 830 840 850 860 pF1KB8 YYPGGSYDPRNNSPY--EIENGVVWVSFRGADYSLRAVRMKIRPLVTQ :: : :: . .::.:: ...: :::..: ::::: XP_016 YYSG---------PYTAKTDNGIVWYTWHGWWYSLKSVVMKIRPNDFIPNVI 270 280 290 300 310 866 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 17:50:48 2016 done: Sat Nov 5 17:50:50 2016 Total Scan time: 15.110 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]