Result of FASTA (omim) for
pF1KB8518
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8518, 869 aa
1>>>pF1KB8518 869 - 869 aa - 869 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.6650+/-0.000737; mu= -8.0933+/- 0.045
mean_var=927.2904+/-215.062, 0's: 0 Z-trim(115.2): 1068 B-trim: 1497 in 1/58
Lambda= 0.042118
statistics sampled from 24436 (25558) to 24436 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.652), E-opt: 0.2 (0.3), width: 16
Scan time: 12.010
The best scores are: opt bits E(85289)
NP_005583 (OMIM: 208150,601296,616325) muscle, ske ( 869) 5836 372.4 5e-102
XP_005252053 (OMIM: 208150,601296,616325) PREDICTE ( 861) 5752 367.3 1.7e-100
XP_005252052 (OMIM: 208150,601296,616325) PREDICTE ( 871) 5722 365.5 6.2e-100
XP_005252051 (OMIM: 208150,601296,616325) PREDICTE ( 879) 4480 290.0 3.2e-77
NP_001159753 (OMIM: 208150,601296,616325) muscle, ( 773) 3360 221.9 9.3e-57
NP_001159752 (OMIM: 208150,601296,616325) muscle, ( 783) 3336 220.4 2.6e-56
XP_016870223 (OMIM: 208150,601296,616325) PREDICTE ( 791) 3234 214.2 1.9e-54
XP_011517010 (OMIM: 208150,601296,616325) PREDICTE ( 457) 3105 206.0 3.3e-52
XP_011539828 (OMIM: 602336) PREDICTED: inactive ty ( 874) 930 74.3 2.8e-12
XP_016856866 (OMIM: 602336) PREDICTED: inactive ty ( 874) 930 74.3 2.8e-12
XP_016856865 (OMIM: 602336) PREDICTED: inactive ty ( 917) 930 74.3 2.8e-12
NP_005003 (OMIM: 602336) inactive tyrosine-protein ( 937) 930 74.4 2.9e-12
XP_005252066 (OMIM: 113000,268310,602337) PREDICTE ( 542) 876 70.7 2.1e-11
XP_005252065 (OMIM: 113000,268310,602337) PREDICTE ( 803) 876 71.0 2.6e-11
XP_016870252 (OMIM: 113000,268310,602337) PREDICTE ( 803) 876 71.0 2.6e-11
XP_006717184 (OMIM: 113000,268310,602337) PREDICTE ( 803) 876 71.0 2.6e-11
XP_016870251 (OMIM: 113000,268310,602337) PREDICTE ( 940) 876 71.1 2.8e-11
NP_004551 (OMIM: 113000,268310,602337) tyrosine-pr ( 943) 876 71.1 2.8e-11
XP_016877741 (OMIM: 191316) PREDICTED: NT-3 growth ( 448) 814 66.8 2.6e-10
XP_016877740 (OMIM: 191316) PREDICTED: NT-3 growth ( 456) 814 66.8 2.7e-10
XP_016877735 (OMIM: 191316) PREDICTED: NT-3 growth ( 727) 814 67.1 3.4e-10
XP_016877733 (OMIM: 191316) PREDICTED: NT-3 growth ( 727) 814 67.1 3.4e-10
XP_016877734 (OMIM: 191316) PREDICTED: NT-3 growth ( 727) 814 67.1 3.4e-10
XP_016877732 (OMIM: 191316) PREDICTED: NT-3 growth ( 727) 814 67.1 3.4e-10
XP_016877730 (OMIM: 191316) PREDICTED: NT-3 growth ( 763) 814 67.2 3.4e-10
XP_006720607 (OMIM: 191316) PREDICTED: NT-3 growth ( 817) 814 67.2 3.6e-10
NP_001230030 (OMIM: 191316) NT-3 growth factor rec ( 817) 814 67.2 3.6e-10
NP_002521 (OMIM: 191316) NT-3 growth factor recept ( 825) 814 67.2 3.6e-10
XP_006720606 (OMIM: 191316) PREDICTED: NT-3 growth ( 825) 814 67.2 3.6e-10
XP_016877729 (OMIM: 191316) PREDICTED: NT-3 growth ( 825) 814 67.2 3.6e-10
XP_011532767 (OMIM: 134935) PREDICTED: fibroblast ( 696) 798 66.1 6.4e-10
NP_075252 (OMIM: 134935) fibroblast growth factor ( 762) 798 66.2 6.7e-10
NP_002002 (OMIM: 134935) fibroblast growth factor ( 802) 798 66.2 6.9e-10
XP_005265895 (OMIM: 134935) PREDICTED: fibroblast ( 802) 798 66.2 6.9e-10
NP_998812 (OMIM: 134935) fibroblast growth factor ( 802) 798 66.2 6.9e-10
XP_011532766 (OMIM: 134935) PREDICTED: fibroblast ( 833) 798 66.3 7e-10
NP_001278909 (OMIM: 134935) fibroblast growth fact ( 734) 776 64.8 1.7e-09
NP_001945 (OMIM: 600408) epithelial discoidin doma ( 876) 776 65.0 1.8e-09
NP_001284581 (OMIM: 600408) epithelial discoidin d ( 876) 776 65.0 1.8e-09
NP_001284582 (OMIM: 600408) epithelial discoidin d ( 876) 776 65.0 1.8e-09
NP_001189452 (OMIM: 600408) epithelial discoidin d ( 894) 776 65.0 1.8e-09
NP_054699 (OMIM: 600408) epithelial discoidin doma ( 913) 776 65.0 1.9e-09
NP_001284583 (OMIM: 600408) epithelial discoidin d ( 913) 776 65.0 1.9e-09
XP_006715248 (OMIM: 600408) PREDICTED: epithelial ( 931) 776 65.0 1.9e-09
NP_065681 (OMIM: 142623,155240,162300,164761,17130 (1072) 773 64.9 2.3e-09
NP_066124 (OMIM: 142623,155240,162300,164761,17130 (1114) 773 64.9 2.3e-09
XP_016868719 (OMIM: 101600,123150,136350,147950,16 ( 498) 758 63.4 2.9e-09
XP_016868718 (OMIM: 101600,123150,136350,147950,16 ( 508) 758 63.5 3e-09
XP_016868717 (OMIM: 101600,123150,136350,147950,16 ( 729) 758 63.7 3.6e-09
XP_016868716 (OMIM: 101600,123150,136350,147950,16 ( 762) 758 63.8 3.6e-09
>>NP_005583 (OMIM: 208150,601296,616325) muscle, skeleta (869 aa)
initn: 5836 init1: 5836 opt: 5836 Z-score: 1952.6 bits: 372.4 E(85289): 5e-102
Smith-Waterman score: 5836; 100.0% identity (100.0% similar) in 869 aa overlap (1-869:1-869)
10 20 30 40 50 60
pF1KB8 MRELVNIPLVHILTLVAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MRELVNIPLVHILTLVAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 WTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 WTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVLESGSLRIHNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVLESGSLRIHNV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 QKEDAGQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHNVTFGSFVTLHCTATGIPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QKEDAGQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHNVTFGSFVTLHCTATGIPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ISIAEWSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ISIAEWSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 VVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 LYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 SSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 SELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPY
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 EPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAY
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 GDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 FVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 TESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWS
790 800 810 820 830 840
850 860
pF1KB8 KLPADRPSFTSIHRILERMCERAEGTVSV
:::::::::::::::::::::::::::::
NP_005 KLPADRPSFTSIHRILERMCERAEGTVSV
850 860
>>XP_005252053 (OMIM: 208150,601296,616325) PREDICTED: m (861 aa)
initn: 3031 init1: 3031 opt: 5752 Z-score: 1925.1 bits: 367.3 E(85289): 1.7e-100
Smith-Waterman score: 5752; 99.0% identity (99.1% similar) in 869 aa overlap (1-869:1-861)
10 20 30 40 50 60
pF1KB8 MRELVNIPLVHILTLVAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRELVNIPLVHILTLVAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 WTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVLESGSLRIHNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVLESGSLRIHNV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 QKEDAGQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHNVTFGSFVTLHCTATGIPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QKEDAGQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHNVTFGSFVTLHCTATGIPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ISIAEWSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ISIAEWSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 VVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 LYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPS
::::::::::::::::::::::::::::::::: .::::::::::::::::::
XP_005 LYRSEMHLLSVPECSKLPSMHWDPTACARLPHL--------AFPPMTSSKPSVDIPNLPS
430 440 450 460 470
490 500 510 520 530 540
pF1KB8 SSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLP
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB8 SELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPY
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB8 EPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAY
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB8 GDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERK
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB8 FVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYT
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB8 TESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWS
780 790 800 810 820 830
850 860
pF1KB8 KLPADRPSFTSIHRILERMCERAEGTVSV
:::::::::::::::::::::::::::::
XP_005 KLPADRPSFTSIHRILERMCERAEGTVSV
840 850 860
>>XP_005252052 (OMIM: 208150,601296,616325) PREDICTED: m (871 aa)
initn: 4094 init1: 2749 opt: 5722 Z-score: 1915.2 bits: 365.5 E(85289): 6.2e-100
Smith-Waterman score: 5722; 97.8% identity (98.0% similar) in 879 aa overlap (1-869:1-871)
10 20 30 40 50 60
pF1KB8 MRELVNIPLVHILTLVAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRELVNIPLVHILTLVAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 WTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVLESGSLRIHNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVLESGSLRIHNV
130 140 150 160 170 180
190 200 210 220 230
pF1KB8 QKEDAGQYRCVAKNSLGTAYSKVVKLEVE----------VFARILRAPESHNVTFGSFVT
::::::::::::::::::::::::::::: :::::::::::::::::::::
XP_005 QKEDAGQYRCVAKNSLGTAYSKVVKLEVEEESEPEQDTKVFARILRAPESHNVTFGSFVT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 LHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 KFSTAKAAATISIAEWSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KFSTAKAAATISIAEWSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQEL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 LVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEW
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB8 LVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSK
::::::::::::::::::::::::::::::::::::::::::: .::::::::
XP_005 LVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHL--------AFPPMTSSK
430 440 450 460 470
480 490 500 510 520 530
pF1KB8 PSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRE
480 490 500 510 520 530
540 550 560 570 580 590
pF1KB8 SAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVF
540 550 560 570 580 590
600 610 620 630 640 650
pF1KB8 QARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKP
600 610 620 630 640 650
660 670 680 690 700 710
pF1KB8 MCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVA
660 670 680 690 700 710
720 730 740 750 760 770
pF1KB8 AGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMP
720 730 740 750 760 770
780 790 800 810 820 830
pF1KB8 PESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVE
780 790 800 810 820 830
840 850 860
pF1KB8 LYNLMRLCWSKLPADRPSFTSIHRILERMCERAEGTVSV
:::::::::::::::::::::::::::::::::::::::
XP_005 LYNLMRLCWSKLPADRPSFTSIHRILERMCERAEGTVSV
840 850 860 870
>>XP_005252051 (OMIM: 208150,601296,616325) PREDICTED: m (879 aa)
initn: 4480 init1: 4480 opt: 4480 Z-score: 1507.3 bits: 290.0 E(85289): 3.2e-77
Smith-Waterman score: 5806; 98.9% identity (98.9% similar) in 879 aa overlap (1-869:1-879)
10 20 30 40 50 60
pF1KB8 MRELVNIPLVHILTLVAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRELVNIPLVHILTLVAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 WTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVLESGSLRIHNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVLESGSLRIHNV
130 140 150 160 170 180
190 200 210 220 230
pF1KB8 QKEDAGQYRCVAKNSLGTAYSKVVKLEVE----------VFARILRAPESHNVTFGSFVT
::::::::::::::::::::::::::::: :::::::::::::::::::::
XP_005 QKEDAGQYRCVAKNSLGTAYSKVVKLEVEEESEPEQDTKVFARILRAPESHNVTFGSFVT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 LHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 KFSTAKAAATISIAEWSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KFSTAKAAATISIAEWSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQEL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 LVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEW
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB8 LVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSK
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB8 PSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRE
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB8 SAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVF
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB8 QARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKP
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB8 MCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVA
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB8 AGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMP
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB8 PESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVE
790 800 810 820 830 840
840 850 860
pF1KB8 LYNLMRLCWSKLPADRPSFTSIHRILERMCERAEGTVSV
:::::::::::::::::::::::::::::::::::::::
XP_005 LYNLMRLCWSKLPADRPSFTSIHRILERMCERAEGTVSV
850 860 870
>>NP_001159753 (OMIM: 208150,601296,616325) muscle, skel (773 aa)
initn: 4722 init1: 2749 opt: 3360 Z-score: 1140.0 bits: 221.9 E(85289): 9.3e-57
Smith-Waterman score: 4951; 88.8% identity (89.0% similar) in 869 aa overlap (1-869:1-773)
10 20 30 40 50 60
pF1KB8 MRELVNIPLVHILTLVAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRELVNIPLVHILTLVAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 WTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVLESGSLRIHNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVLESGSLRIHNV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 QKEDAGQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHNVTFGSFVTLHCTATGIPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKEDAGQYRCVAKNSLGTAYSKVVKLEVEVFARILRAPESHNVTFGSFVTLHCTATGIPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 PTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGEKFSTAKAAAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ISIAEWSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQELLVHTAWNELK
::::::
NP_001 ISIAEW------------------------------------------------------
370 380 390 400 410 420
pF1KB8 VVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRG
::::::::::::::::::::::::::
NP_001 ----------------------------------REYCLAVKELFCAKEWLVMEEKTHRG
310 320 330
430 440 450 460 470 480
pF1KB8 LYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPS
::::::::::::::::::::::::::::::::: .::::::::::::::::::
NP_001 LYRSEMHLLSVPECSKLPSMHWDPTACARLPHL--------AFPPMTSSKPSVDIPNLPS
340 350 360 370 380
490 500 510 520 530 540
pF1KB8 SSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLP
390 400 410 420 430 440
550 560 570 580 590 600
pF1KB8 SELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPY
450 460 470 480 490 500
610 620 630 640 650 660
pF1KB8 EPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAY
510 520 530 540 550 560
670 680 690 700 710 720
pF1KB8 GDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERK
570 580 590 600 610 620
730 740 750 760 770 780
pF1KB8 FVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYT
630 640 650 660 670 680
790 800 810 820 830 840
pF1KB8 TESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWS
690 700 710 720 730 740
850 860
pF1KB8 KLPADRPSFTSIHRILERMCERAEGTVSV
:::::::::::::::::::::::::::::
NP_001 KLPADRPSFTSIHRILERMCERAEGTVSV
750 760 770
>>NP_001159752 (OMIM: 208150,601296,616325) muscle, skel (783 aa)
initn: 4094 init1: 2749 opt: 3336 Z-score: 1132.0 bits: 220.4 E(85289): 2.6e-56
Smith-Waterman score: 4921; 87.8% identity (87.9% similar) in 879 aa overlap (1-869:1-783)
10 20 30 40 50 60
pF1KB8 MRELVNIPLVHILTLVAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRELVNIPLVHILTLVAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 WTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVLESGSLRIHNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVLESGSLRIHNV
130 140 150 160 170 180
190 200 210 220 230
pF1KB8 QKEDAGQYRCVAKNSLGTAYSKVVKLEVE----------VFARILRAPESHNVTFGSFVT
::::::::::::::::::::::::::::: :::::::::::::::::::::
NP_001 QKEDAGQYRCVAKNSLGTAYSKVVKLEVEEESEPEQDTKVFARILRAPESHNVTFGSFVT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 LHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 KFSTAKAAATISIAEWSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQEL
::::::::::::::::
NP_001 KFSTAKAAATISIAEW--------------------------------------------
310
360 370 380 390 400 410
pF1KB8 LVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEW
::::::::::::::::
NP_001 --------------------------------------------REYCLAVKELFCAKEW
320 330
420 430 440 450 460 470
pF1KB8 LVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSK
::::::::::::::::::::::::::::::::::::::::::: .::::::::
NP_001 LVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHL--------AFPPMTSSK
340 350 360 370 380
480 490 500 510 520 530
pF1KB8 PSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRE
390 400 410 420 430 440
540 550 560 570 580 590
pF1KB8 SAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVF
450 460 470 480 490 500
600 610 620 630 640 650
pF1KB8 QARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKP
510 520 530 540 550 560
660 670 680 690 700 710
pF1KB8 MCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVA
570 580 590 600 610 620
720 730 740 750 760 770
pF1KB8 AGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMP
630 640 650 660 670 680
780 790 800 810 820 830
pF1KB8 PESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVE
690 700 710 720 730 740
840 850 860
pF1KB8 LYNLMRLCWSKLPADRPSFTSIHRILERMCERAEGTVSV
:::::::::::::::::::::::::::::::::::::::
NP_001 LYNLMRLCWSKLPADRPSFTSIHRILERMCERAEGTVSV
750 760 770 780
>>XP_016870223 (OMIM: 208150,601296,616325) PREDICTED: m (791 aa)
initn: 4579 init1: 3234 opt: 3234 Z-score: 1098.5 bits: 214.2 E(85289): 1.9e-54
Smith-Waterman score: 5005; 88.9% identity (88.9% similar) in 879 aa overlap (1-869:1-791)
10 20 30 40 50 60
pF1KB8 MRELVNIPLVHILTLVAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MRELVNIPLVHILTLVAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 WTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVLESGSLRIHNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVLESGSLRIHNV
130 140 150 160 170 180
190 200 210 220 230
pF1KB8 QKEDAGQYRCVAKNSLGTAYSKVVKLEVE----------VFARILRAPESHNVTFGSFVT
::::::::::::::::::::::::::::: :::::::::::::::::::::
XP_016 QKEDAGQYRCVAKNSLGTAYSKVVKLEVEEESEPEQDTKVFARILRAPESHNVTFGSFVT
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 LHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHCTATGIPVPTITWIENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 KFSTAKAAATISIAEWSKPQKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPEEAQEL
::::::::::::::::
XP_016 KFSTAKAAATISIAEW--------------------------------------------
310
360 370 380 390 400 410
pF1KB8 LVHTAWNELKVVSPVCRPAAEALLCNHIFQECSPGVVPTPIPICREYCLAVKELFCAKEW
::::::::::::::::
XP_016 --------------------------------------------REYCLAVKELFCAKEW
320 330
420 430 440 450 460 470
pF1KB8 LVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVMEEKTHRGLYRSEMHLLSVPECSKLPSMHWDPTACARLPHLDYNKENLKTFPPMTSSK
340 350 360 370 380 390
480 490 500 510 520 530
pF1KB8 PSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSVDIPNLPSSSSSSFSVSPTYSMTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRE
400 410 420 430 440 450
540 550 560 570 580 590
pF1KB8 SAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAAVTLTTLPSELLLDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVF
460 470 480 490 500 510
600 610 620 630 640 650
pF1KB8 QARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QARAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKP
520 530 540 550 560 570
660 670 680 690 700 710
pF1KB8 MCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVA
580 590 600 610 620 630
720 730 740 750 760 770
pF1KB8 AGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMP
640 650 660 670 680 690
780 790 800 810 820 830
pF1KB8 PESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVE
700 710 720 730 740 750
840 850 860
pF1KB8 LYNLMRLCWSKLPADRPSFTSIHRILERMCERAEGTVSV
:::::::::::::::::::::::::::::::::::::::
XP_016 LYNLMRLCWSKLPADRPSFTSIHRILERMCERAEGTVSV
760 770 780 790
>>XP_011517010 (OMIM: 208150,601296,616325) PREDICTED: m (457 aa)
initn: 3105 init1: 3105 opt: 3105 Z-score: 1058.2 bits: 206.0 E(85289): 3.3e-52
Smith-Waterman score: 3105; 100.0% identity (100.0% similar) in 457 aa overlap (413-869:1-457)
390 400 410 420 430 440
pF1KB8 SPGVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHRGLYRSEMHLLSVPECSKLPSMHW
::::::::::::::::::::::::::::::
XP_011 MEEKTHRGLYRSEMHLLSVPECSKLPSMHW
10 20 30
450 460 470 480 490 500
pF1KB8 DPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPTACARLPHLDYNKENLKTFPPMTSSKPSVDIPNLPSSSSSSFSVSPTYSMTVIISIMS
40 50 60 70 80 90
510 520 530 540 550 560
pF1KB8 SFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELLLDRLHPNPMYQRMPLLLN
100 110 120 130 140 150
570 580 590 600 610 620
pF1KB8 PKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEPFTMVAVKMLKEEASADMQAD
160 170 180 190 200 210
630 640 650 660 670 680
pF1KB8 FQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSD
220 230 240 250 260 270
690 700 710 720 730 740
pF1KB8 LSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIA
280 290 300 310 320 330
750 760 770 780 790 800
pF1KB8 DFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQP
340 350 360 370 380 390
810 820 830 840 850 860
pF1KB8 YYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPADRPSFTSIHRILERMCER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKLPADRPSFTSIHRILERMCER
400 410 420 430 440 450
pF1KB8 AEGTVSV
:::::::
XP_011 AEGTVSV
>>XP_011539828 (OMIM: 602336) PREDICTED: inactive tyrosi (874 aa)
initn: 821 init1: 670 opt: 930 Z-score: 341.5 bits: 74.3 E(85289): 2.8e-12
Smith-Waterman score: 1133; 32.3% identity (59.4% similar) in 711 aa overlap (221-853:2-680)
200 210 220 230 240
pF1KB8 VAKNSLGTAYSKVVKLEVEVFARILRAPESHNVT--FGSFVTLHCTATGIPVPTITWIEN
.:.: .:. . ::: ..: : ::: :..:
XP_011 MNNITTSLGQTAELHCKVSGNPPPTIRWFKN
10 20 30
250 260 270 280 290 300
pF1KB8 GNAVSSGSIQESVKDRVIDSRLQ---LFITKPGLYTCIATNKHGEKFSTAKAAATISIAE
: . . : .. . :::. : : : . :.::: . ::. . ..
XP_011 DAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPP
40 50 60 70 80 90
310 320 330 340 350 360
pF1KB8 WSKP----QKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPE-EAQELLVHTAWNELK
..: . .. :.: ::: .: : . . :.... . . : : : . : . .
XP_011 TASPGYSDEYEEDGFCQPYRGIAC-ARFIGNRTVYMESLHMQGEIENQITAAFTMIGTSS
100 110 120 130 140 150
370 380 390 400 410
pF1KB8 VVSPVCRPAAEALLCNHIFQECSP-GVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHR
.: : : ::.. : :. . :: : .::. : .....: :. .. ...
XP_011 HLSDKCSQFAIPSLCHYAFPYCDETSSVPKPRDLCRDECEILENVLCQTEY-IFARSNPM
160 170 180 190 200
420 430 440 450 460
pF1KB8 GLYRSEMHLLSVPECSKLPSMHWDPTA--CARL--PHLDYNKENLKTF------------
:.: :..:.: ::. . .: : : :. : : ..: : .
XP_011 ILMR-----LKLPNCEDLPQPE-SPEAANCIRIGIPMADPINKNHKCYNSTGVDYRGTVS
210 220 230 240 250 260
470 480 490
pF1KB8 --------PPMTSSKP------SVDIPNL---------PSSSSSS---FSVSPTYS----
: .:. : .. .:.: :.... . :... ...
XP_011 VTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEAPWCFTLDENFKSDLC
270 280 290 300 310 320
500 510 520 530
pF1KB8 ---------------MTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTT
: .. .. : :: . ... .. : :. :.: :: :
XP_011 DIPACDSKDSKEKNKMEILYILVPSVAIPLAIALLFFFICVCRN---NQKSSSAPV--QR
330 340 350 360 370
540 550 560 570 580 590
pF1KB8 LPSELLLDRLHPNPMYQRMPLL--LNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARA--
:. : . .: .: .:: . : : . .......:: :::......
XP_011 QPK-------HVRGQNVEMSMLNAYKPKSKAKELPLSAVRFMEELGECAFGKIYKGHLYL
380 390 400 410 420 430
600 610 620 630 640 650
pF1KB8 PGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLL
::. . .::.: ::. . .. ..::.::.::::. .:::: :::. . .:.:.:
XP_011 PGM---DHAQLVAIKTLKDYNNPQQWTEFQQEASLMAELHHPNIVCLLGAVTQEQPVCML
440 450 460 470 480
660 670 680 690 700 710
pF1KB8 FEYMAYGDLNEFLRSMSPHTV--CSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAG
:::. :::.::: :::. :: : : ..... :. .. : :: :.:::
XP_011 FEYINQGDLHEFLIMRSPHSDVGCS-SDEDGTVKSS--------LDHGDFLHIAIQIAAG
490 500 510 520 530
720 730 740 750 760 770
pF1KB8 MAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPE
: ::: . :::.:::.:: :.::.. :::.:.::::.:::::::... .. .::::::::
XP_011 MEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREIYSADYYRVQSKSLLPIRWMPPE
540 550 560 570 580 590
780 790 800 810 820 830
pF1KB8 SIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELY
.:.:......::.:..:::::::::.:::::::....::: .:: ..: : :.:: ..:
XP_011 AIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMVRKRQLLPCSEDCPPRMY
600 610 620 630 640 650
840 850 860
pF1KB8 NLMRLCWSKLPADRPSFTSIHRILERMCERAEGTVSV
.:: ::...:. :: : .::
XP_011 SLMTECWNEIPSRRPRFKDIHVRLRSWEGLSSHTSSTTPSGGNATTQTTSLSASPVSNLS
660 670 680 690 700 710
>>XP_016856866 (OMIM: 602336) PREDICTED: inactive tyrosi (874 aa)
initn: 821 init1: 670 opt: 930 Z-score: 341.5 bits: 74.3 E(85289): 2.8e-12
Smith-Waterman score: 1133; 32.3% identity (59.4% similar) in 711 aa overlap (221-853:2-680)
200 210 220 230 240
pF1KB8 VAKNSLGTAYSKVVKLEVEVFARILRAPESHNVT--FGSFVTLHCTATGIPVPTITWIEN
.:.: .:. . ::: ..: : ::: :..:
XP_016 MNNITTSLGQTAELHCKVSGNPPPTIRWFKN
10 20 30
250 260 270 280 290 300
pF1KB8 GNAVSSGSIQESVKDRVIDSRLQ---LFITKPGLYTCIATNKHGEKFSTAKAAATISIAE
: . . : .. . :::. : : : . :.::: . ::. . ..
XP_016 DAPVVQEPRRLSFRSTIYGSRLRIRNLDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPP
40 50 60 70 80 90
310 320 330 340 350 360
pF1KB8 WSKP----QKDNKGYCAQYRGEVCNAVLAKDALVFLNTSYADPE-EAQELLVHTAWNELK
..: . .. :.: ::: .: : . . :.... . . : : : . : . .
XP_016 TASPGYSDEYEEDGFCQPYRGIAC-ARFIGNRTVYMESLHMQGEIENQITAAFTMIGTSS
100 110 120 130 140 150
370 380 390 400 410
pF1KB8 VVSPVCRPAAEALLCNHIFQECSP-GVVPTPIPICREYCLAVKELFCAKEWLVMEEKTHR
.: : : ::.. : :. . :: : .::. : .....: :. .. ...
XP_016 HLSDKCSQFAIPSLCHYAFPYCDETSSVPKPRDLCRDECEILENVLCQTEY-IFARSNPM
160 170 180 190 200
420 430 440 450 460
pF1KB8 GLYRSEMHLLSVPECSKLPSMHWDPTA--CARL--PHLDYNKENLKTF------------
:.: :..:.: ::. . .: : : :. : : ..: : .
XP_016 ILMR-----LKLPNCEDLPQPE-SPEAANCIRIGIPMADPINKNHKCYNSTGVDYRGTVS
210 220 230 240 250 260
470 480 490
pF1KB8 --------PPMTSSKP------SVDIPNL---------PSSSSSS---FSVSPTYS----
: .:. : .. .:.: :.... . :... ...
XP_016 VTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNPGNQKEAPWCFTLDENFKSDLC
270 280 290 300 310 320
500 510 520 530
pF1KB8 ---------------MTVIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTT
: .. .. : :: . ... .. : :. :.: :: :
XP_016 DIPACDSKDSKEKNKMEILYILVPSVAIPLAIALLFFFICVCRN---NQKSSSAPV--QR
330 340 350 360 370
540 550 560 570 580 590
pF1KB8 LPSELLLDRLHPNPMYQRMPLL--LNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARA--
:. : . .: .: .:: . : : . .......:: :::......
XP_016 QPK-------HVRGQNVEMSMLNAYKPKSKAKELPLSAVRFMEELGECAFGKIYKGHLYL
380 390 400 410 420 430
600 610 620 630 640 650
pF1KB8 PGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLL
::. . .::.: ::. . .. ..::.::.::::. .:::: :::. . .:.:.:
XP_016 PGM---DHAQLVAIKTLKDYNNPQQWTEFQQEASLMAELHHPNIVCLLGAVTQEQPVCML
440 450 460 470 480
660 670 680 690 700 710
pF1KB8 FEYMAYGDLNEFLRSMSPHTV--CSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAG
:::. :::.::: :::. :: : : ..... :. .. : :: :.:::
XP_016 FEYINQGDLHEFLIMRSPHSDVGCS-SDEDGTVKSS--------LDHGDFLHIAIQIAAG
490 500 510 520 530
720 730 740 750 760 770
pF1KB8 MAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPE
: ::: . :::.:::.:: :.::.. :::.:.::::.:::::::... .. .::::::::
XP_016 MEYLSSHFFVHKDLAARNILIGEQLHVKISDLGLSREIYSADYYRVQSKSLLPIRWMPPE
540 550 560 570 580 590
780 790 800 810 820 830
pF1KB8 SIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELY
.:.:......::.:..:::::::::.:::::::....::: .:: ..: : :.:: ..:
XP_016 AIMYGKFSSDSDIWSFGVVLWEIFSFGLQPYYGFSNQEVIEMVRKRQLLPCSEDCPPRMY
600 610 620 630 640 650
840 850 860
pF1KB8 NLMRLCWSKLPADRPSFTSIHRILERMCERAEGTVSV
.:: ::...:. :: : .::
XP_016 SLMTECWNEIPSRRPRFKDIHVRLRSWEGLSSHTSSTTPSGGNATTQTTSLSASPVSNLS
660 670 680 690 700 710
869 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 10:25:42 2016 done: Sun Nov 6 10:25:43 2016
Total Scan time: 12.010 Total Display time: 0.270
Function used was FASTA [36.3.4 Apr, 2011]