FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8528, 885 aa 1>>>pF1KB8528 885 - 885 aa - 885 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.2145+/-0.000992; mu= 12.3062+/- 0.060 mean_var=116.4626+/-23.179, 0's: 0 Z-trim(108.0): 28 B-trim: 0 in 0/51 Lambda= 0.118845 statistics sampled from 9951 (9957) to 9951 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.665), E-opt: 0.2 (0.306), width: 16 Scan time: 4.370 The best scores are: opt bits E(32554) CCDS30584.1 EXOSC10 gene_id:5394|Hs108|chr1 ( 885) 5937 1029.6 0 CCDS126.1 EXOSC10 gene_id:5394|Hs108|chr1 ( 860) 4739 824.1 0 >>CCDS30584.1 EXOSC10 gene_id:5394|Hs108|chr1 (885 aa) initn: 5937 init1: 5937 opt: 5937 Z-score: 5503.9 bits: 1029.6 E(32554): 0 Smith-Waterman score: 5937; 100.0% identity (100.0% similar) in 885 aa overlap (1-885:1-885) 10 20 30 40 50 60 pF1KB8 MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEI 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 SNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 SNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKR 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB8 ERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS30 ERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQF 790 800 810 820 830 840 850 860 870 880 pF1KB8 DPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR ::::::::::::::::::::::::::::::::::::::::::::: CCDS30 DPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR 850 860 870 880 >>CCDS126.1 EXOSC10 gene_id:5394|Hs108|chr1 (860 aa) initn: 5756 init1: 4686 opt: 4739 Z-score: 4394.0 bits: 824.1 E(32554): 0 Smith-Waterman score: 5710; 97.2% identity (97.2% similar) in 885 aa overlap (1-885:1-860) 10 20 30 40 50 60 pF1KB8 MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEI :::::::::::::::::::::::::::::::::: : CCDS12 FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRM-------------------------I 670 680 690 730 740 750 760 770 780 pF1KB8 SNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 SNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKR 700 710 720 730 740 750 790 800 810 820 830 840 pF1KB8 ERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 ERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQF 760 770 780 790 800 810 850 860 870 880 pF1KB8 DPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR ::::::::::::::::::::::::::::::::::::::::::::: CCDS12 DPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR 820 830 840 850 860 885 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:35:36 2016 done: Sat Nov 5 16:35:36 2016 Total Scan time: 4.370 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]