Result of FASTA (omim) for pF1KB8528
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8528, 885 aa
  1>>>pF1KB8528 885 - 885 aa - 885 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.7526+/-0.00043; mu= 15.3148+/- 0.027
 mean_var=123.9535+/-25.151, 0's: 0 Z-trim(115.1): 20  B-trim: 1208 in 1/49
 Lambda= 0.115198
 statistics sampled from 25278 (25296) to 25278 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.653), E-opt: 0.2 (0.297), width:  16
 Scan time: 13.290

The best scores are:                                      opt bits E(85289)
NP_001001998 (OMIM: 605960) exosome component 10 i ( 885) 5937 998.7       0
XP_005263532 (OMIM: 605960) PREDICTED: exosome com ( 890) 5917 995.4       0
NP_002676 (OMIM: 605960) exosome component 10 isof ( 860) 4739 799.6       0
XP_016856984 (OMIM: 605960) PREDICTED: exosome com ( 469) 3064 521.0 5.1e-147
XP_016856983 (OMIM: 605960) PREDICTED: exosome com ( 474) 3044 517.7 5.1e-146
XP_016856986 (OMIM: 605960) PREDICTED: exosome com ( 453) 3026 514.7 3.9e-145
XP_016856985 (OMIM: 605960) PREDICTED: exosome com ( 458) 3006 511.4  4e-144


>>NP_001001998 (OMIM: 605960) exosome component 10 isofo  (885 aa)
 initn: 5937 init1: 5937 opt: 5937  Z-score: 5337.1  bits: 998.7 E(85289):    0
Smith-Waterman score: 5937; 100.0% identity (100.0% similar) in 885 aa overlap (1-885:1-885)

               10        20        30        40        50        60
pF1KB8 MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB8 AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB8 RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB8 FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEI
              670       680       690       700       710       720

              730       740       750       760       770       780
pF1KB8 SNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKR
              730       740       750       760       770       780

              790       800       810       820       830       840
pF1KB8 ERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQF
              790       800       810       820       830       840

              850       860       870       880     
pF1KB8 DPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR
       :::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR
              850       860       870       880     

>>XP_005263532 (OMIM: 605960) PREDICTED: exosome compone  (890 aa)
 initn: 5923 init1: 5026 opt: 5917  Z-score: 5319.2  bits: 995.4 E(85289):    0
Smith-Waterman score: 5917; 99.4% identity (99.4% similar) in 890 aa overlap (1-885:1-890)

               10        20        30        40        50        60
pF1KB8 MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB8 AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB8 RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB8 FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEI
              670       680       690       700       710       720

              730       740            750       760       770     
pF1KB8 SNRWKLAQVQVQKDSKEAVKKKAAEQT-----AAREQAKEACKAAAEQAISVRQQVVLEN
       :::::::::::::::::::::::::::     ::::::::::::::::::::::::::::
XP_005 SNRWKLAQVQVQKDSKEAVKKKAAEQTVLSLAAAREQAKEACKAAAEQAISVRQQVVLEN
              730       740       750       760       770       780

         780       790       800       810       820       830     
pF1KB8 AAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSK
              790       800       810       820       830       840

         840       850       860       870       880     
pF1KB8 VSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR
       ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR
              850       860       870       880       890

>>NP_002676 (OMIM: 605960) exosome component 10 isoform   (860 aa)
 initn: 5756 init1: 4686 opt: 4739  Z-score: 4261.3  bits: 799.6 E(85289):    0
Smith-Waterman score: 5710; 97.2% identity (97.2% similar) in 885 aa overlap (1-885:1-860)

               10        20        30        40        50        60
pF1KB8 MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVI
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNI
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVEL
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPA
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKK
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB8 FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKI
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB8 AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAE
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB8 RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITL
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB8 FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEI
       ::::::::::::::::::::::::::::::::::                         :
NP_002 FNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRM-------------------------I
              670       680       690                              

              730       740       750       760       770       780
pF1KB8 SNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKR
         700       710       720       730       740       750     

              790       800       810       820       830       840
pF1KB8 ERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQF
         760       770       780       790       800       810     

              850       860       870       880     
pF1KB8 DPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR
       :::::::::::::::::::::::::::::::::::::::::::::
NP_002 DPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR
         820       830       840       850       860

>>XP_016856984 (OMIM: 605960) PREDICTED: exosome compone  (469 aa)
 initn: 3064 init1: 3064 opt: 3064  Z-score: 2760.5  bits: 521.0 E(85289): 5.1e-147
Smith-Waterman score: 3064; 99.6% identity (99.8% similar) in 460 aa overlap (426-885:10-469)

         400       410       420       430       440       450     
pF1KB8 LNLGRHSLDHLLKLYCNVDSNKQYQLADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEM
                                     . ::::::::::::::::::::::::::::
XP_016                      MRASQTQPSLSPLPEEMLSYARDDTHYLLYIYDKMRLEM
                                    10        20        30         

         460       470       480       490       500       510     
pF1KB8 WERGNGQPVQLQVVWQRSRDICLKKFIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WERGNGQPVQLQVVWQRSRDICLKKFIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFA
      40        50        60        70        80        90         

         520       530       540       550       560       570     
pF1KB8 WRDKTARREDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WRDKTARREDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQ
     100       110       120       130       140       150         

         580       590       600       610       620       630     
pF1KB8 AREMPLLKSEVAAGVKKSGPLPSAERLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AREMPLLKSEVAAGVKKSGPLPSAERLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQA
     160       170       180       190       200       210         

         640       650       660       670       680       690     
pF1KB8 SLFPDEKEDNLLGTTCLIATAVITLFNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLFPDEKEDNLLGTTCLIATAVITLFNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMF
     220       230       240       250       260       270         

         700       710       720       730       740       750     
pF1KB8 LPSLGHRAPVSQAAKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPSLGHRAPVSQAAKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKE
     280       290       300       310       320       330         

         760       770       780       790       800       810     
pF1KB8 ACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEF
     340       350       360       370       380       390         

         820       830       840       850       860       870     
pF1KB8 TPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSD
     400       410       420       430       440       450         

         880     
pF1KB8 RGFRYNWPQR
       ::::::::::
XP_016 RGFRYNWPQR
     460         

>>XP_016856983 (OMIM: 605960) PREDICTED: exosome compone  (474 aa)
 initn: 3050 init1: 2153 opt: 3044  Z-score: 2742.5  bits: 517.7 E(85289): 5.1e-146
Smith-Waterman score: 3044; 98.5% identity (98.7% similar) in 465 aa overlap (426-885:10-474)

         400       410       420       430       440       450     
pF1KB8 LNLGRHSLDHLLKLYCNVDSNKQYQLADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEM
                                     . ::::::::::::::::::::::::::::
XP_016                      MRASQTQPSLSPLPEEMLSYARDDTHYLLYIYDKMRLEM
                                    10        20        30         

         460       470       480       490       500       510     
pF1KB8 WERGNGQPVQLQVVWQRSRDICLKKFIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WERGNGQPVQLQVVWQRSRDICLKKFIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFA
      40        50        60        70        80        90         

         520       530       540       550       560       570     
pF1KB8 WRDKTARREDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WRDKTARREDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQ
     100       110       120       130       140       150         

         580       590       600       610       620       630     
pF1KB8 AREMPLLKSEVAAGVKKSGPLPSAERLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AREMPLLKSEVAAGVKKSGPLPSAERLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQA
     160       170       180       190       200       210         

         640       650       660       670       680       690     
pF1KB8 SLFPDEKEDNLLGTTCLIATAVITLFNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLFPDEKEDNLLGTTCLIATAVITLFNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMF
     220       230       240       250       260       270         

         700       710       720       730       740            750
pF1KB8 LPSLGHRAPVSQAAKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQT-----AAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::     :::
XP_016 LPSLGHRAPVSQAAKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQTVLSLAAAR
     280       290       300       310       320       330         

              760       770       780       790       800       810
pF1KB8 EQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEP
     340       350       360       370       380       390         

              820       830       840       850       860       870
pF1KB8 PEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFP
     400       410       420       430       440       450         

              880     
pF1KB8 TGKSDRGFRYNWPQR
       :::::::::::::::
XP_016 TGKSDRGFRYNWPQR
     460       470    

>>XP_016856986 (OMIM: 605960) PREDICTED: exosome compone  (453 aa)
 initn: 3026 init1: 3026 opt: 3026  Z-score: 2726.6  bits: 514.7 E(85289): 3.9e-145
Smith-Waterman score: 3026; 100.0% identity (100.0% similar) in 453 aa overlap (433-885:1-453)

            410       420       430       440       450       460  
pF1KB8 LDHLLKLYCNVDSNKQYQLADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQ
                                     ::::::::::::::::::::::::::::::
XP_016                               MLSYARDDTHYLLYIYDKMRLEMWERGNGQ
                                             10        20        30

            470       480       490       500       510       520  
pF1KB8 PVQLQVVWQRSRDICLKKFIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVQLQVVWQRSRDICLKKFIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTAR
               40        50        60        70        80        90

            530       540       550       560       570       580  
pF1KB8 REDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLL
              100       110       120       130       140       150

            590       600       610       620       630       640  
pF1KB8 KSEVAAGVKKSGPLPSAERLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSEVAAGVKKSGPLPSAERLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEK
              160       170       180       190       200       210

            650       660       670       680       690       700  
pF1KB8 EDNLLGTTCLIATAVITLFNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDNLLGTTCLIATAVITLFNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHR
              220       230       240       250       260       270

            710       720       730       740       750       760  
pF1KB8 APVSQAAKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APVSQAAKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAE
              280       290       300       310       320       330

            770       780       790       800       810       820  
pF1KB8 QAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQ
              340       350       360       370       380       390

            830       840       850       860       870       880  
pF1KB8 SDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNW
              400       410       420       430       440       450

          
pF1KB8 PQR
       :::
XP_016 PQR
          

>>XP_016856985 (OMIM: 605960) PREDICTED: exosome compone  (458 aa)
 initn: 3012 init1: 2115 opt: 3006  Z-score: 2708.5  bits: 511.4 E(85289): 4e-144
Smith-Waterman score: 3006; 98.9% identity (98.9% similar) in 458 aa overlap (433-885:1-458)

            410       420       430       440       450       460  
pF1KB8 LDHLLKLYCNVDSNKQYQLADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQ
                                     ::::::::::::::::::::::::::::::
XP_016                               MLSYARDDTHYLLYIYDKMRLEMWERGNGQ
                                             10        20        30

            470       480       490       500       510       520  
pF1KB8 PVQLQVVWQRSRDICLKKFIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTAR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVQLQVVWQRSRDICLKKFIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTAR
               40        50        60        70        80        90

            530       540       550       560       570       580  
pF1KB8 REDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLL
              100       110       120       130       140       150

            590       600       610       620       630       640  
pF1KB8 KSEVAAGVKKSGPLPSAERLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSEVAAGVKKSGPLPSAERLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEK
              160       170       180       190       200       210

            650       660       670       680       690       700  
pF1KB8 EDNLLGTTCLIATAVITLFNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDNLLGTTCLIATAVITLFNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHR
              220       230       240       250       260       270

            710       720       730       740            750       
pF1KB8 APVSQAAKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQT-----AAREQAKEAC
       :::::::::::::::::::::::::::::::::::::::::::::     ::::::::::
XP_016 APVSQAAKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQTVLSLAAAREQAKEAC
              280       290       300       310       320       330

       760       770       780       790       800       810       
pF1KB8 KAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTP
              340       350       360       370       380       390

       820       830       840       850       860       870       
pF1KB8 YDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRG
              400       410       420       430       440       450

       880     
pF1KB8 FRYNWPQR
       ::::::::
XP_016 FRYNWPQR
               




885 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 16:35:36 2016 done: Sat Nov  5 16:35:38 2016
 Total Scan time: 13.290 Total Display time:  0.130

Function used was FASTA [36.3.4 Apr, 2011]
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