FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8545, 984 aa 1>>>pF1KB8545 984 - 984 aa - 984 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.1828+/-0.000535; mu= -0.6274+/- 0.033 mean_var=534.2604+/-121.813, 0's: 0 Z-trim(118.1): 1795 B-trim: 690 in 1/57 Lambda= 0.055488 statistics sampled from 28122 (30680) to 28122 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.687), E-opt: 0.2 (0.36), width: 16 Scan time: 12.820 The best scores are: opt bits E(85289) NP_006247 (OMIM: 602549) serine/threonine-protein ( 984) 6513 538.0 9.2e-152 NP_001307637 (OMIM: 602549) serine/threonine-prote ( 827) 5506 457.3 1.5e-127 XP_011540074 (OMIM: 602549) PREDICTED: serine/thre ( 658) 4439 371.7 7e-102 XP_016857271 (OMIM: 602549) PREDICTED: serine/thre ( 922) 4087 343.8 2.6e-93 NP_001307638 (OMIM: 602549) serine/threonine-prote ( 968) 4055 341.2 1.6e-92 XP_016857272 (OMIM: 602549) PREDICTED: serine/thre ( 920) 3486 295.6 7.8e-79 NP_001307636 (OMIM: 602549) serine/threonine-prote ( 936) 3454 293.1 4.6e-78 NP_002732 (OMIM: 601032) serine/threonine-protein ( 942) 1901 168.8 1.2e-40 NP_998725 (OMIM: 601032) serine/threonine-protein ( 948) 1901 168.8 1.2e-40 XP_011526430 (OMIM: 601032) PREDICTED: serine/thre ( 954) 1901 168.8 1.2e-40 XP_016870139 (OMIM: 610714) PREDICTED: serine/thre ( 763) 1569 142.1 1.1e-32 XP_005252003 (OMIM: 610714) PREDICTED: serine/thre ( 886) 1569 142.2 1.2e-32 NP_037487 (OMIM: 610714) serine/threonine-protein ( 889) 1569 142.2 1.2e-32 XP_006717143 (OMIM: 610714) PREDICTED: serine/thre ( 896) 1569 142.2 1.2e-32 NP_001304855 (OMIM: 610714) serine/threonine-prote ( 833) 1301 120.7 3.3e-26 XP_016870138 (OMIM: 610714) PREDICTED: serine/thre ( 840) 1301 120.7 3.3e-26 XP_011531285 (OMIM: 176975) PREDICTED: protein kin ( 436) 1206 112.7 4.5e-24 XP_006712113 (OMIM: 176975) PREDICTED: protein kin ( 460) 1206 112.7 4.6e-24 XP_011531284 (OMIM: 176975) PREDICTED: protein kin ( 497) 1206 112.7 4.8e-24 XP_016859980 (OMIM: 176975) PREDICTED: protein kin ( 587) 1206 112.8 5.3e-24 XP_011531282 (OMIM: 176975) PREDICTED: protein kin ( 587) 1206 112.8 5.3e-24 XP_016859978 (OMIM: 176975) PREDICTED: protein kin ( 587) 1206 112.8 5.3e-24 XP_016859979 (OMIM: 176975) PREDICTED: protein kin ( 587) 1206 112.8 5.3e-24 XP_011531283 (OMIM: 176975) PREDICTED: protein kin ( 587) 1206 112.8 5.3e-24 XP_016859976 (OMIM: 176975) PREDICTED: protein kin ( 623) 1206 112.9 5.5e-24 XP_011531280 (OMIM: 176975) PREDICTED: protein kin ( 623) 1206 112.9 5.5e-24 XP_016859977 (OMIM: 176975) PREDICTED: protein kin ( 623) 1206 112.9 5.5e-24 XP_011531277 (OMIM: 176975) PREDICTED: protein kin ( 641) 1206 112.9 5.6e-24 XP_016859975 (OMIM: 176975) PREDICTED: protein kin ( 641) 1206 112.9 5.6e-24 XP_011531273 (OMIM: 176975) PREDICTED: protein kin ( 641) 1206 112.9 5.6e-24 XP_005264485 (OMIM: 176975) PREDICTED: protein kin ( 737) 1206 113.0 6e-24 NP_005391 (OMIM: 176975) protein kinase C epsilon ( 737) 1206 113.0 6e-24 NP_001310195 (OMIM: 600448) protein kinase C theta ( 581) 1137 107.3 2.4e-22 NP_001269574 (OMIM: 600448) protein kinase C theta ( 581) 1137 107.3 2.4e-22 XP_016871900 (OMIM: 600448) PREDICTED: protein kin ( 581) 1137 107.3 2.4e-22 NP_001269573 (OMIM: 600448) protein kinase C theta ( 670) 1137 107.4 2.6e-22 NP_006248 (OMIM: 600448) protein kinase C theta ty ( 706) 1137 107.4 2.7e-22 XP_016871899 (OMIM: 600448) PREDICTED: protein kin ( 706) 1137 107.4 2.7e-22 XP_006717528 (OMIM: 600448) PREDICTED: protein kin ( 706) 1137 107.4 2.7e-22 NP_001310194 (OMIM: 600448) protein kinase C theta ( 706) 1137 107.4 2.7e-22 XP_005252553 (OMIM: 600448) PREDICTED: protein kin ( 740) 1137 107.5 2.8e-22 XP_016876947 (OMIM: 601367,605437) PREDICTED: prot ( 522) 1133 106.9 2.8e-22 XP_011535257 (OMIM: 601367,605437) PREDICTED: prot ( 603) 1133 107.0 3.1e-22 XP_011535256 (OMIM: 601367,605437) PREDICTED: prot ( 604) 1133 107.0 3.1e-22 NP_006246 (OMIM: 601367,605437) protein kinase C e ( 683) 1133 107.1 3.3e-22 XP_016880327 (OMIM: 176960) PREDICTED: protein kin ( 586) 1126 106.4 4.5e-22 XP_016880329 (OMIM: 176960) PREDICTED: protein kin ( 586) 1126 106.4 4.5e-22 XP_016880328 (OMIM: 176960) PREDICTED: protein kin ( 586) 1126 106.4 4.5e-22 NP_002728 (OMIM: 176960) protein kinase C alpha ty ( 672) 1127 106.6 4.6e-22 XP_016880326 (OMIM: 176960) PREDICTED: protein kin ( 621) 1126 106.5 4.6e-22 >>NP_006247 (OMIM: 602549) serine/threonine-protein kina (984 aa) initn: 6513 init1: 6513 opt: 6513 Z-score: 2845.6 bits: 538.0 E(85289): 9.2e-152 Smith-Waterman score: 6513; 100.0% identity (100.0% similar) in 984 aa overlap (1-984:1-984) 10 20 30 40 50 60 pF1KB8 MASNPERGEILLTELQGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MASNPERGEILLTELQGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KIKEGAENLRKVTTDKKSLAYVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITDCPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 KIKEGAENLRKVTTDKKSLAYVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITDCPR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TPDTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TPDTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 QDSKTKIEVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 QDSKTKIEVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 KLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 KLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 ASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 ASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 PSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 FTLELDRSRELEISVYWRDWRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 FTLELDRSRELEISVYWRDWRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 PVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNHSGTFSPQAPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNHSGTFSPQAPV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 PTTVPVVDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDESSELRVLDIPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PTTVPVVDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDESSELRVLDIPG 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 QDSETVFDIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELEDRRSQQRFQFNLQDFRCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 QDSETVFDIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELEDRRSQQRFQFNLQDFRCC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 AVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 AVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 VNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 VNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVY 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB8 RDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDW 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB8 WGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 WGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRL 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB8 GASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 GASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPP 910 920 930 940 950 960 970 980 pF1KB8 REPRILSEEEQEMFRDFDYIADWC :::::::::::::::::::::::: NP_006 REPRILSEEEQEMFRDFDYIADWC 970 980 >>NP_001307637 (OMIM: 602549) serine/threonine-protein k (827 aa) initn: 5506 init1: 5506 opt: 5506 Z-score: 2410.7 bits: 457.3 E(85289): 1.5e-127 Smith-Waterman score: 5506; 100.0% identity (100.0% similar) in 827 aa overlap (158-984:1-827) 130 140 150 160 170 180 pF1KB8 DPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLLQDSKTKI :::::::::::::::::::::::::::::: NP_001 MIQMYSNGSSKDRKLHGTAQQLLQDSKTKI 10 20 30 190 200 210 220 230 240 pF1KB8 EVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVMKLLGSGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVMKLLGSGK 40 50 60 70 80 90 250 260 270 280 290 300 pF1KB8 VTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVAASPTLSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVAASPTLSP 100 110 120 130 140 150 310 320 330 340 350 360 pF1KB8 RQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWSPSETRSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWSPSETRSS 160 170 180 190 200 210 370 380 390 400 410 420 pF1KB8 FMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQKFTLELDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQKFTLELDR 220 230 240 250 260 270 430 440 450 460 470 480 pF1KB8 SRELEISVYWRDWRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SRELEISVYWRDWRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFNPVIERRP 280 290 300 310 320 330 490 500 510 520 530 540 pF1KB8 KLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNHSGTFSPQAPVPTTVPVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNHSGTFSPQAPVPTTVPVV 340 350 360 370 380 390 550 560 570 580 590 600 pF1KB8 DVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDESSELRVLDIPGQDSETVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDESSELRVLDIPGQDSETVF 400 410 420 430 440 450 610 620 630 640 650 660 pF1KB8 DIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELEDRRSQQRFQFNLQDFRCCAVLGRGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELEDRRSQQRFQFNLQDFRCCAVLGRGH 460 470 480 490 500 510 670 680 690 700 710 720 pF1KB8 FGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFLVNLFACF 520 530 540 550 560 570 730 740 750 760 770 780 pF1KB8 QTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDN 580 590 600 610 620 630 790 800 810 820 830 840 pF1KB8 LLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLI 640 650 660 670 680 690 850 860 870 880 890 900 pF1KB8 YEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGASEKDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRLGASEKDA 700 710 720 730 740 750 910 920 930 940 950 960 pF1KB8 EDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPPREPRILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPPREPRILS 760 770 780 790 800 810 970 980 pF1KB8 EEEQEMFRDFDYIADWC ::::::::::::::::: NP_001 EEEQEMFRDFDYIADWC 820 >>XP_011540074 (OMIM: 602549) PREDICTED: serine/threonin (658 aa) initn: 4439 init1: 4439 opt: 4439 Z-score: 1950.1 bits: 371.7 E(85289): 7e-102 Smith-Waterman score: 4439; 99.5% identity (100.0% similar) in 658 aa overlap (327-984:1-658) 300 310 320 330 340 350 pF1KB8 SLVAASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVAL ...::::::::::::::::::::::::::: XP_011 MNSTLEVRLMGCQDILENVPGRSKATSVAL 10 20 30 360 370 380 390 400 410 pF1KB8 PGWSPSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PGWSPSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQS 40 50 60 70 80 90 420 430 440 450 460 470 pF1KB8 WDQKFTLELDRSRELEISVYWRDWRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WDQKFTLELDRSRELEISVYWRDWRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEV 100 110 120 130 140 150 480 490 500 510 520 530 pF1KB8 TFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNHSGTFSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNHSGTFSP 160 170 180 190 200 210 540 550 560 570 580 590 pF1KB8 QAPVPTTVPVVDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDESSELRVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QAPVPTTVPVVDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDESSELRVL 220 230 240 250 260 270 600 610 620 630 640 650 pF1KB8 DIPGQDSETVFDIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELEDRRSQQRFQFNLQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DIPGQDSETVFDIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELEDRRSQQRFQFNLQD 280 290 300 310 320 330 660 670 680 690 700 710 pF1KB8 FRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVR 340 350 360 370 380 390 720 730 740 750 760 770 pF1KB8 HPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEH 400 410 420 430 440 450 780 790 800 810 820 830 pF1KB8 KIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTR 460 470 480 490 500 510 840 850 860 870 880 890 pF1KB8 AVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNP 520 530 540 550 560 570 900 910 920 930 940 950 pF1KB8 ERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPI 580 590 600 610 620 630 960 970 980 pF1KB8 LTPPREPRILSEEEQEMFRDFDYIADWC :::::::::::::::::::::::::::: XP_011 LTPPREPRILSEEEQEMFRDFDYIADWC 640 650 >>XP_016857271 (OMIM: 602549) PREDICTED: serine/threonin (922 aa) initn: 4049 init1: 4049 opt: 4087 Z-score: 1796.4 bits: 343.8 E(85289): 2.6e-93 Smith-Waterman score: 5977; 93.6% identity (93.7% similar) in 984 aa overlap (1-984:1-922) 10 20 30 40 50 60 pF1KB8 MASNPERGEILLTELQGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MASNPERGEILLTELQGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KIKEGAENLRKVTTDKKSLAYVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITDCPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KIKEGAENLRKVTTDKKSLAYVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITDCPR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TPDTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPDTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 QDSKTKIEVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QDSKTKIEVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 KLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 ASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWS :::::::::::::::::::::::::::: XP_016 ASPTLSPRQSMISTQNQYSTLSKPAALT-------------------------------- 310 320 370 380 390 400 410 420 pF1KB8 PSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQK .::::::::::::::::::::::::::::: XP_016 ------------------------------DDVCAVLKLDNTVVGQTSWKPISNQSWDQK 330 340 350 430 440 450 460 470 480 pF1KB8 FTLELDRSRELEISVYWRDWRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FTLELDRSRELEISVYWRDWRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFN 360 370 380 390 400 410 490 500 510 520 530 540 pF1KB8 PVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNHSGTFSPQAPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNHSGTFSPQAPV 420 430 440 450 460 470 550 560 570 580 590 600 pF1KB8 PTTVPVVDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDESSELRVLDIPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTTVPVVDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDESSELRVLDIPG 480 490 500 510 520 530 610 620 630 640 650 660 pF1KB8 QDSETVFDIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELEDRRSQQRFQFNLQDFRCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QDSETVFDIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELEDRRSQQRFQFNLQDFRCC 540 550 560 570 580 590 670 680 690 700 710 720 pF1KB8 AVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFL 600 610 620 630 640 650 730 740 750 760 770 780 pF1KB8 VNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVY 660 670 680 690 700 710 790 800 810 820 830 840 pF1KB8 RDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDW 720 730 740 750 760 770 850 860 870 880 890 900 pF1KB8 WGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRL 780 790 800 810 820 830 910 920 930 940 950 960 pF1KB8 GASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPP 840 850 860 870 880 890 970 980 pF1KB8 REPRILSEEEQEMFRDFDYIADWC :::::::::::::::::::::::: XP_016 REPRILSEEEQEMFRDFDYIADWC 900 910 920 >>NP_001307638 (OMIM: 602549) serine/threonine-protein k (968 aa) initn: 4047 init1: 4047 opt: 4055 Z-score: 1782.3 bits: 341.2 E(85289): 1.6e-92 Smith-Waterman score: 6376; 98.4% identity (98.4% similar) in 984 aa overlap (1-984:1-968) 10 20 30 40 50 60 pF1KB8 MASNPERGEILLTELQGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MASNPERGEILLTELQGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KIKEGAENLRKVTTDKKSLAYVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITDCPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KIKEGAENLRKVTTDKKSLAYVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITDCPR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TPDTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPDTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 QDSKTKIEVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QDSKTKIEVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 KLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 ASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 PSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQK :::::::::::::: :::::::::::::::::::::::::::::: NP_001 PSETRSSFMSRTSK----------------NDVCAVLKLDNTVVGQTSWKPISNQSWDQK 370 380 390 400 430 440 450 460 470 480 pF1KB8 FTLELDRSRELEISVYWRDWRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTLELDRSRELEISVYWRDWRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFN 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB8 PVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNHSGTFSPQAPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNHSGTFSPQAPV 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB8 PTTVPVVDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDESSELRVLDIPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTTVPVVDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDESSELRVLDIPG 530 540 550 560 570 580 610 620 630 640 650 660 pF1KB8 QDSETVFDIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELEDRRSQQRFQFNLQDFRCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QDSETVFDIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELEDRRSQQRFQFNLQDFRCC 590 600 610 620 630 640 670 680 690 700 710 720 pF1KB8 AVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFL 650 660 670 680 690 700 730 740 750 760 770 780 pF1KB8 VNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVY 710 720 730 740 750 760 790 800 810 820 830 840 pF1KB8 RDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDW 770 780 790 800 810 820 850 860 870 880 890 900 pF1KB8 WGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRL 830 840 850 860 870 880 910 920 930 940 950 960 pF1KB8 GASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPP 890 900 910 920 930 940 970 980 pF1KB8 REPRILSEEEQEMFRDFDYIADWC :::::::::::::::::::::::: NP_001 REPRILSEEEQEMFRDFDYIADWC 950 960 >>XP_016857272 (OMIM: 602549) PREDICTED: serine/threonin (920 aa) initn: 5811 init1: 3453 opt: 3486 Z-score: 1536.4 bits: 295.6 E(85289): 7.8e-79 Smith-Waterman score: 5930; 93.5% identity (93.5% similar) in 984 aa overlap (1-984:1-920) 10 20 30 40 50 60 pF1KB8 MASNPERGEILLTELQGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MASNPERGEILLTELQGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KIKEGAENLRKVTTDKKSLAYVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITDCPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KIKEGAENLRKVTTDKKSLAYVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITDCPR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TPDTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TPDTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 QDSKTKIEVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QDSKTKIEVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 KLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 ASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 PSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQK :::::::::::::: :::::::::::::::::::::::::::::: XP_016 PSETRSSFMSRTSK----------------NDVCAVLKLDNTVVGQTSWKPISNQSWDQK 370 380 390 400 430 440 450 460 470 480 pF1KB8 FTLELDRSRELEISVYWRDWRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFN ::::::: ::::: XP_016 FTLELDR------------------------------------------------VTFFN 410 490 500 510 520 530 540 pF1KB8 PVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNHSGTFSPQAPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNHSGTFSPQAPV 420 430 440 450 460 470 550 560 570 580 590 600 pF1KB8 PTTVPVVDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDESSELRVLDIPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PTTVPVVDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDESSELRVLDIPG 480 490 500 510 520 530 610 620 630 640 650 660 pF1KB8 QDSETVFDIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELEDRRSQQRFQFNLQDFRCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QDSETVFDIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELEDRRSQQRFQFNLQDFRCC 540 550 560 570 580 590 670 680 690 700 710 720 pF1KB8 AVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFL 600 610 620 630 640 650 730 740 750 760 770 780 pF1KB8 VNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVY 660 670 680 690 700 710 790 800 810 820 830 840 pF1KB8 RDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDW 720 730 740 750 760 770 850 860 870 880 890 900 pF1KB8 WGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRL 780 790 800 810 820 830 910 920 930 940 950 960 pF1KB8 GASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPP 840 850 860 870 880 890 970 980 pF1KB8 REPRILSEEEQEMFRDFDYIADWC :::::::::::::::::::::::: XP_016 REPRILSEEEQEMFRDFDYIADWC 900 910 920 >>NP_001307636 (OMIM: 602549) serine/threonine-protein k (936 aa) initn: 6159 init1: 3453 opt: 3454 Z-score: 1522.4 bits: 293.1 E(85289): 4.6e-78 Smith-Waterman score: 6067; 95.1% identity (95.1% similar) in 984 aa overlap (1-984:1-936) 10 20 30 40 50 60 pF1KB8 MASNPERGEILLTELQGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MASNPERGEILLTELQGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKEL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KIKEGAENLRKVTTDKKSLAYVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITDCPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KIKEGAENLRKVTTDKKSLAYVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITDCPR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 TPDTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TPDTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 QDSKTKIEVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QDSKTKIEVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 KLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 ASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWS 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 PSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 FTLELDRSRELEISVYWRDWRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFN ::::::: ::::: NP_001 FTLELDR------------------------------------------------VTFFN 430 490 500 510 520 530 540 pF1KB8 PVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNHSGTFSPQAPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNHSGTFSPQAPV 440 450 460 470 480 490 550 560 570 580 590 600 pF1KB8 PTTVPVVDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDESSELRVLDIPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTTVPVVDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDESSELRVLDIPG 500 510 520 530 540 550 610 620 630 640 650 660 pF1KB8 QDSETVFDIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELEDRRSQQRFQFNLQDFRCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QDSETVFDIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELEDRRSQQRFQFNLQDFRCC 560 570 580 590 600 610 670 680 690 700 710 720 pF1KB8 AVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFL 620 630 640 650 660 670 730 740 750 760 770 780 pF1KB8 VNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVY 680 690 700 710 720 730 790 800 810 820 830 840 pF1KB8 RDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDW 740 750 760 770 780 790 850 860 870 880 890 900 pF1KB8 WGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRL 800 810 820 830 840 850 910 920 930 940 950 960 pF1KB8 GASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPP 860 870 880 890 900 910 970 980 pF1KB8 REPRILSEEEQEMFRDFDYIADWC :::::::::::::::::::::::: NP_001 REPRILSEEEQEMFRDFDYIADWC 920 930 >>NP_002732 (OMIM: 601032) serine/threonine-protein kina (942 aa) initn: 3488 init1: 1876 opt: 1901 Z-score: 850.5 bits: 168.8 E(85289): 1.2e-40 Smith-Waterman score: 3664; 59.7% identity (80.0% similar) in 986 aa overlap (15-984:6-942) 10 20 30 40 50 60 pF1KB8 MASNPERGEILLTELQGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKEL .:.. :: . :... . :.. :::.:. ..:..::::::: NP_002 MASDAVQSEPRSWSLLEQLG-LAGADLAAPGVQQQLELERERLRREIRKEL 10 20 30 40 50 70 80 90 100 110 pF1KB8 KIKEGAENLRKVTTD-KKSLAYVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITDCP :.::::::::..::: .::. :. .:. :...:. ::..::::.::.:. :: : : NP_002 KLKEGAENLRRATTDLGRSLGPVELLLRGSSRRLDLLHQQLQELHAHVVLPDPAATHDGP 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 RTPDTPNNDPRCSTSN-NRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQ ..: . . : ::..: .:. .:.::: :::::::::::::: :::::.::::: :::: NP_002 QSPGA--GGPTCSATNLSRVAGLEKQLAIELKVKQGAENMIQTYSNGSTKDRKLLLTAQQ 120 130 140 150 160 180 190 200 210 220 230 pF1KB8 LLQDSKTKIEVIRMQILQAVQTNEL----AFDNAK--PVISPLELRMEELRHHFRIEFAV .::::::::..::::. .:.:...: : :... : .. .:::.::::::::.: :: NP_002 MLQDSKTKIDIIRMQLRRALQAGQLENQAAPDDTQGSPDLGAVELRIEELRHHFRVEHAV 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB8 AEGAKNVMKLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKSRII :::::::..::...:. ::::.:::: ...::.::: ::. .::.::.:.: .:::.:.. NP_002 AEGAKNVLRLLSAAKAPDRKAVSEAQEKLTESNQKLGLLREALERRLGELPADHPKGRLL 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB8 IEELSLVAASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKAT :::. .:.: ..: : . ..:::: ::: ::::::::..::.:. :..: . . NP_002 REELA-AASSAAFSTRLAGPFPATHYSTLCKPAPLTGTLEVRVVGCRDLPETIPW-NPTP 290 300 310 320 330 340 360 370 380 390 400 pF1KB8 SVALPGWSPSETRSSFMSRTSK---SKSGS--SRNLLKTD-DLSNDVCAVLKLDNTVVGQ :.. :: .: ..: :.:: .. :.::: .:. ::.. . ...: .::::::::::: NP_002 SMGGPG-TP-DSRPPFLSRPARGLYSRSGSLSGRSSLKAEAENTSEVSTVLKLDNTVVGQ 350 360 370 380 390 400 410 420 430 440 450 460 pF1KB8 TSWKPISNQSWDQKFTLELDRSRELEISVYWRDWRSLCAVKFLRLEDFLDNQRHGMCLYL ::::: . ..:::.:::::.:.::::..:.::: :.:::.:::.:::::::.:: . : . NP_002 TSWKPCGPNAWDQSFTLELERARELELAVFWRDQRGLCALKFLKLEDFLDNERHEVQLDM 410 420 430 440 450 460 470 480 490 500 510 520 pF1KB8 EPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIP :::: : ::::: :::::: :.:.::::::::::::.: :: ::::..::: ::.:: :: NP_002 EPQGCLVAEVTFRNPVIERIPRLRRQKKIFSKQQGKAFQRARQMNIDVATWVRLLRRLIP 470 480 490 500 510 520 530 540 550 560 570 580 pF1KB8 TVNHSGTFSPQA-PVPTTVPVVDVRIPQLA-PPASDSTVTKLDFDLEPEPPPAPPRASSL ... .::::: : : . . :. . .: :::. : . : :: .: :: NP_002 NATGTGTFSPGASPGSEARTTGDISVEKLNLGTDSDSSPQKSSRD----PPSSPSSLSS- 530 540 550 560 570 590 600 610 620 630 640 pF1KB8 GEIDESSELRVLDIPGQDSETVFDIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELEDR : :.: . :. :: . .:: .: : . : NP_002 --------------PIQESTA------------PELPSETQ-ETPGPALC-SPL-----R 580 590 600 650 660 670 680 690 700 pF1KB8 RSQQRFQFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMC .: ..:.::. :::::::::::::.:.. ..:.:::::::::::::::::.:::: NP_002 KS----PLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMC 610 620 630 640 650 660 710 720 730 740 750 760 pF1KB8 EKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAA ::::. .:.:. ::::::::.:::: :::::::::.::::::.:::.::::::::.::.: NP_002 EKRILAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVFSEPRAIFYSA 670 680 690 700 710 720 770 780 790 800 810 820 pF1KB8 CVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFL :::::::.::::::::::::::::::::::.::::::::::::::::::::::::::::: NP_002 CVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFL 730 740 750 760 770 780 830 840 850 860 870 880 pF1KB8 APEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEA ::::::.:::::::::::::::.::::::::::::::::::::::::::::::::::.:: NP_002 APEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEA 790 800 810 820 830 840 890 900 910 920 930 940 pF1KB8 ISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVS :.:::::::::::::::.::.:::::::.:::: . : ::. ... :::.::. :: ::: NP_002 IGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTDVS 850 860 870 880 890 900 950 960 970 980 pF1KB8 NFDDEFTSEAPILTPPREPRILSEEEQEMFRDFDYIADWC :::.:::.::: :.:::. : :. :: : :::..: : NP_002 NFDEEFTGEAPTLSPPRDARPLTAAEQAAFLDFDFVAGGC 910 920 930 940 >>NP_998725 (OMIM: 601032) serine/threonine-protein kina (948 aa) initn: 3488 init1: 1876 opt: 1901 Z-score: 850.5 bits: 168.8 E(85289): 1.2e-40 Smith-Waterman score: 3670; 59.4% identity (79.6% similar) in 999 aa overlap (2-984:4-948) 10 20 30 40 50 pF1KB8 MASNPERGEILLTELQGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRK :.:: . ::... :: . :... . :.. :::.:. ..:..::::: NP_998 MAEANNPSE-----QELESEPRSWSLLEQLG-LAGADLAAPGVQQQLELERERLRREIRK 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 ELKIKEGAENLRKVTTD-KKSLAYVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITD :::.::::::::..::: .::. :. .:. :...:. ::..::::.::.:. :: : NP_998 ELKLKEGAENLRRATTDLGRSLGPVELLLRGSSRRLDLLHQQLQELHAHVVLPDPAATHD 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 CPRTPDTPNNDPRCSTSN-NRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTA :..: . . : ::..: .:. .:.::: :::::::::::::: :::::.::::: :: NP_998 GPQSPGA--GGPTCSATNLSRVAGLEKQLAIELKVKQGAENMIQTYSNGSTKDRKLLLTA 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 QQLLQDSKTKIEVIRMQILQAVQTNEL----AFDNAK--PVISPLELRMEELRHHFRIEF ::.::::::::..::::. .:.:...: : :... : .. .:::.::::::::.: NP_998 QQMLQDSKTKIDIIRMQLRRALQAGQLENQAAPDDTQGSPDLGAVELRIEELRHHFRVEH 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 AVAEGAKNVMKLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKSR :::::::::..::...:. ::::.:::: ...::.::: ::. .::.::.:.: .:::.: NP_998 AVAEGAKNVLRLLSAAKAPDRKAVSEAQEKLTESNQKLGLLREALERRLGELPADHPKGR 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 IIIEELSLVAASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSK .. :::. .:.: ..: : . ..:::: ::: ::::::::..::.:. :..: . NP_998 LLREELA-AASSAAFSTRLAGPFPATHYSTLCKPAPLTGTLEVRVVGCRDLPETIPW-NP 300 310 320 330 340 350 360 370 380 390 400 pF1KB8 ATSVALPGWSPSETRSSFMSRTSK---SKSGS--SRNLLKTD-DLSNDVCAVLKLDNTVV . :.. :: .: ..: :.:: .. :.::: .:. ::.. . ...: .::::::::: NP_998 TPSMGGPG-TP-DSRPPFLSRPARGLYSRSGSLSGRSSLKAEAENTSEVSTVLKLDNTVV 360 370 380 390 400 410 420 430 440 450 460 pF1KB8 GQTSWKPISNQSWDQKFTLELDRSRELEISVYWRDWRSLCAVKFLRLEDFLDNQRHGMCL ::::::: . ..:::.:::::.:.::::..:.::: :.:::.:::.:::::::.:: . : NP_998 GQTSWKPCGPNAWDQSFTLELERARELELAVFWRDQRGLCALKFLKLEDFLDNERHEVQL 410 420 430 440 450 460 470 480 490 500 510 520 pF1KB8 YLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRA .:::: : ::::: :::::: :.:.::::::::::::.: :: ::::..::: ::.:: NP_998 DMEPQGCLVAEVTFRNPVIERIPRLRRQKKIFSKQQGKAFQRARQMNIDVATWVRLLRRL 470 480 490 500 510 520 530 540 550 560 570 580 pF1KB8 IPTVNHSGTFSPQA-PVPTTVPVVDVRIPQLA-PPASDSTVTKLDFDLEPEPPPAPPRAS ::... .::::: : : . . :. . .: :::. : . : :: .: : NP_998 IPNATGTGTFSPGASPGSEARTTGDISVEKLNLGTDSDSSPQKSSRD----PPSSPSSLS 530 540 550 560 570 580 590 600 610 620 630 640 pF1KB8 SLGEIDESSELRVLDIPGQDSETVFDIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELE : : :.: . :. :: . .:: .: : . NP_998 S---------------PIQESTA------------PELPSETQ-ETPGPALC-SPL---- 590 600 610 650 660 670 680 690 700 pF1KB8 DRRSQQRFQFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSL :.: ..:.::. :::::::::::::.:.. ..:.:::::::::::::::::.:: NP_998 -RKSP----LTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESL 620 630 640 650 660 710 720 730 740 750 760 pF1KB8 MCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFY ::::::. .:.:. ::::::::.:::: :::::::::.::::::.:::.::::::::.:: NP_998 MCEKRILAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVFSEPRAIFY 670 680 690 700 710 720 770 780 790 800 810 820 pF1KB8 AACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPE .::::::::.::::::::::::::::::::::.::::::::::::::::::::::::::: NP_998 SACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPE 730 740 750 760 770 780 830 840 850 860 870 880 pF1KB8 FLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLST ::::::::.:::::::::::::::.::::::::::::::::::::::::::::::::::. NP_998 FLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSA 790 800 810 820 830 840 890 900 910 920 930 940 pF1KB8 EAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGRED :::.:::::::::::::::.::.:::::::.:::: . : ::. ... :::.::. :: : NP_998 EAIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRTD 850 860 870 880 890 900 950 960 970 980 pF1KB8 VSNFDDEFTSEAPILTPPREPRILSEEEQEMFRDFDYIADWC :::::.:::.::: :.:::. : :. :: : :::..: : NP_998 VSNFDEEFTGEAPTLSPPRDARPLTAAEQAAFLDFDFVAGGC 910 920 930 940 >>XP_011526430 (OMIM: 601032) PREDICTED: serine/threonin (954 aa) initn: 3488 init1: 1876 opt: 1901 Z-score: 850.5 bits: 168.8 E(85289): 1.2e-40 Smith-Waterman score: 3663; 59.1% identity (79.2% similar) in 1003 aa overlap (1-984:1-954) 10 20 30 40 50 pF1KB8 MASNPERGEILL---TELQGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIR :: : :: . ... :: . :... . :.. :::.:. ..:..:::: XP_011 MACRPCRGAGRIWCCRSHKSEPRSWSLLEQLG-LAGADLAAPGVQQQLELERERLRREIR 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 KELKIKEGAENLRKVTTD-KKSLAYVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDIT ::::.::::::::..::: .::. :. .:. :...:. ::..::::.::.:. :: XP_011 KELKLKEGAENLRRATTDLGRSLGPVELLLRGSSRRLDLLHQQLQELHAHVVLPDPAATH 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 DCPRTPDTPNNDPRCSTSN-NRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGT : :..: . . : ::..: .:. .:.::: :::::::::::::: :::::.::::: : XP_011 DGPQSPGA--GGPTCSATNLSRVAGLEKQLAIELKVKQGAENMIQTYSNGSTKDRKLLLT 120 130 140 150 160 170 180 190 200 210 220 pF1KB8 AQQLLQDSKTKIEVIRMQILQAVQTNEL----AFDNAK--PVISPLELRMEELRHHFRIE :::.::::::::..::::. .:.:...: : :... : .. .:::.::::::::.: XP_011 AQQMLQDSKTKIDIIRMQLRRALQAGQLENQAAPDDTQGSPDLGAVELRIEELRHHFRVE 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB8 FAVAEGAKNVMKLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKS :::::::::..::...:. ::::.:::: ...::.::: ::. .::.::.:.: .:::. XP_011 HAVAEGAKNVLRLLSAAKAPDRKAVSEAQEKLTESNQKLGLLREALERRLGELPADHPKG 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB8 RIIIEELSLVAASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRS :.. :::. .:.: ..: : . ..:::: ::: ::::::::..::.:. :..: . XP_011 RLLREELA-AASSAAFSTRLAGPFPATHYSTLCKPAPLTGTLEVRVVGCRDLPETIPW-N 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB8 KATSVALPGWSPSETRSSFMSRTSK---SKSGS--SRNLLKTD-DLSNDVCAVLKLDNTV . :.. :: .: ..: :.:: .. :.::: .:. ::.. . ...: .:::::::: XP_011 PTPSMGGPG-TP-DSRPPFLSRPARGLYSRSGSLSGRSSLKAEAENTSEVSTVLKLDNTV 360 370 380 390 400 410 410 420 430 440 450 460 pF1KB8 VGQTSWKPISNQSWDQKFTLELDRSRELEISVYWRDWRSLCAVKFLRLEDFLDNQRHGMC :::::::: . ..:::.:::::.:.::::..:.::: :.:::.:::.:::::::.:: . XP_011 VGQTSWKPCGPNAWDQSFTLELERARELELAVFWRDQRGLCALKFLKLEDFLDNERHEVQ 420 430 440 450 460 470 470 480 490 500 510 520 pF1KB8 LYLEPQGTLFAEVTFFNPVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRR : .:::: : ::::: :::::: :.:.::::::::::::.: :: ::::..::: ::.:: XP_011 LDMEPQGCLVAEVTFRNPVIERIPRLRRQKKIFSKQQGKAFQRARQMNIDVATWVRLLRR 480 490 500 510 520 530 530 540 550 560 570 580 pF1KB8 AIPTVNHSGTFSPQA-PVPTTVPVVDVRIPQLA-PPASDSTVTKLDFDLEPEPPPAPPRA ::... .::::: : : . . :. . .: :::. : . : :: .: XP_011 LIPNATGTGTFSPGASPGSEARTTGDISVEKLNLGTDSDSSPQKSSRD----PPSSPSSL 540 550 560 570 580 590 600 610 620 630 640 pF1KB8 SSLGEIDESSELRVLDIPGQDSETVFDIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQEL :: : :.: . :. :: . .:: .: : . XP_011 SS---------------PIQESTA------------PELPSETQ-ETPGPALC-SPL--- 590 600 610 650 660 670 680 690 700 pF1KB8 EDRRSQQRFQFNLQDFRCCAVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDS :.: ..:.::. :::::::::::::.:.. ..:.:::::::::::::::::.: XP_011 --RKSP----LTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVES 620 630 640 650 660 670 710 720 730 740 750 760 pF1KB8 LMCEKRIFETVNSVRHPFLVNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVF :::::::. .:.:. ::::::::.:::: :::::::::.::::::.:::.::::::::.: XP_011 LMCEKRILAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVFSEPRAIF 680 690 700 710 720 730 770 780 790 800 810 820 pF1KB8 YAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTP :.::::::::.::::::::::::::::::::::.:::::::::::::::::::::::::: XP_011 YSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTP 740 750 760 770 780 790 830 840 850 860 870 880 pF1KB8 EFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLS :::::::::.:::::::::::::::.:::::::::::::::::::::::::::::::::: XP_011 EFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLS 800 810 820 830 840 850 890 900 910 920 930 940 pF1KB8 TEAISIMRRLLRRNPERRLGASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGRE .:::.:::::::::::::::.::.:::::::.:::: . : ::. ... :::.::. :: XP_011 AEAIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLSGRT 860 870 880 890 900 910 950 960 970 980 pF1KB8 DVSNFDDEFTSEAPILTPPREPRILSEEEQEMFRDFDYIADWC ::::::.:::.::: :.:::. : :. :: : :::..: : XP_011 DVSNFDEEFTGEAPTLSPPRDARPLTAAEQAAFLDFDFVAGGC 920 930 940 950 984 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:40:00 2016 done: Sat Nov 5 16:40:02 2016 Total Scan time: 12.820 Total Display time: 0.370 Function used was FASTA [36.3.4 Apr, 2011]