FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8550, 906 aa 1>>>pF1KB8550 906 - 906 aa - 906 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3601+/-0.000477; mu= 20.5819+/- 0.030 mean_var=67.7419+/-13.647, 0's: 0 Z-trim(108.5): 135 B-trim: 0 in 0/50 Lambda= 0.155828 statistics sampled from 16428 (16563) to 16428 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.534), E-opt: 0.2 (0.194), width: 16 Scan time: 11.690 The best scores are: opt bits E(85289) NP_000818 (OMIM: 138248) glutamate receptor 1 isof ( 906) 6035 1366.8 0 NP_001107655 (OMIM: 138248) glutamate receptor 1 i ( 906) 5976 1353.5 0 NP_001244950 (OMIM: 138248) glutamate receptor 1 i ( 916) 5841 1323.1 0 XP_011535937 (OMIM: 138248) PREDICTED: glutamate r ( 886) 5782 1309.9 0 NP_001244951 (OMIM: 138248) glutamate receptor 1 i ( 916) 5782 1309.9 0 NP_001244952 (OMIM: 138248) glutamate receptor 1 i ( 837) 5567 1261.5 0 XP_016864882 (OMIM: 138248) PREDICTED: glutamate r ( 837) 5508 1248.3 0 NP_001244949 (OMIM: 138248) glutamate receptor 1 i ( 811) 5329 1208.0 0 XP_016864881 (OMIM: 138248) PREDICTED: glutamate r ( 846) 5118 1160.6 0 NP_001244948 (OMIM: 138248) glutamate receptor 1 i ( 826) 4982 1130.0 0 NP_001077088 (OMIM: 138247) glutamate receptor 2 i ( 883) 4173 948.1 0 NP_000817 (OMIM: 138247) glutamate receptor 2 isof ( 883) 4127 937.8 0 XP_005271575 (OMIM: 138246) PREDICTED: glutamate r ( 902) 4086 928.6 0 XP_016863602 (OMIM: 138247) PREDICTED: glutamate r ( 836) 4074 925.9 0 XP_016863603 (OMIM: 138247) PREDICTED: glutamate r ( 836) 4074 925.9 0 XP_016863604 (OMIM: 138247) PREDICTED: glutamate r ( 836) 4074 925.9 0 NP_001070711 (OMIM: 138246) glutamate receptor 4 i ( 884) 4072 925.4 0 XP_006718886 (OMIM: 138246) PREDICTED: glutamate r ( 902) 4030 916.0 0 XP_016863605 (OMIM: 138247) PREDICTED: glutamate r ( 836) 4028 915.5 0 XP_016863606 (OMIM: 138247) PREDICTED: glutamate r ( 836) 4028 915.5 0 XP_011541077 (OMIM: 138246) PREDICTED: glutamate r ( 884) 4026 915.1 0 NP_001077089 (OMIM: 138247) glutamate receptor 2 i ( 836) 4022 914.2 0 NP_000820 (OMIM: 138246) glutamate receptor 4 isof ( 902) 4020 913.8 0 NP_000819 (OMIM: 300699,305915) glutamate receptor ( 894) 3907 888.4 0 NP_015564 (OMIM: 300699,305915) glutamate receptor ( 894) 3862 878.2 0 XP_016873098 (OMIM: 138246) PREDICTED: glutamate r ( 814) 3817 868.1 0 XP_016873099 (OMIM: 138246) PREDICTED: glutamate r ( 771) 3555 809.2 0 XP_011541079 (OMIM: 138246) PREDICTED: glutamate r ( 732) 3458 787.4 0 XP_011541078 (OMIM: 138246) PREDICTED: glutamate r ( 732) 3458 787.4 0 XP_016873100 (OMIM: 138246) PREDICTED: glutamate r ( 732) 3458 787.4 0 XP_005261001 (OMIM: 138245) PREDICTED: glutamate r ( 903) 2076 476.7 2.2e-133 NP_001317922 (OMIM: 138245) glutamate receptor ion ( 934) 2060 473.1 2.7e-132 NP_783300 (OMIM: 138245) glutamate receptor ionotr ( 905) 2059 472.9 3.1e-132 NP_000822 (OMIM: 138243) glutamate receptor ionotr ( 919) 2051 471.1 1.1e-131 XP_011534079 (OMIM: 138244,611092) PREDICTED: glut ( 892) 1991 457.6 1.2e-127 NP_001159719 (OMIM: 138244,611092) glutamate recep ( 892) 1991 457.6 1.2e-127 XP_005267003 (OMIM: 138244,611092) PREDICTED: glut ( 859) 1983 455.8 4.1e-127 XP_011534080 (OMIM: 138244,611092) PREDICTED: glut ( 869) 1983 455.8 4.1e-127 NP_786944 (OMIM: 138244,611092) glutamate receptor ( 869) 1983 455.8 4.1e-127 NP_068775 (OMIM: 138244,611092) glutamate receptor ( 908) 1983 455.8 4.3e-127 XP_005267002 (OMIM: 138244,611092) PREDICTED: glut ( 908) 1983 455.8 4.3e-127 NP_001307550 (OMIM: 138245) glutamate receptor ion ( 763) 1853 426.5 2.3e-118 XP_011525164 (OMIM: 600283) PREDICTED: glutamate r ( 981) 1771 408.2 1e-112 XP_011525167 (OMIM: 600283) PREDICTED: glutamate r ( 982) 1765 406.8 2.6e-112 XP_011525170 (OMIM: 600283) PREDICTED: glutamate r ( 901) 1743 401.9 7.4e-111 XP_016882202 (OMIM: 600283) PREDICTED: glutamate r ( 914) 1743 401.9 7.5e-111 NP_002079 (OMIM: 600283) glutamate receptor ionotr ( 980) 1646 380.1 2.9e-104 XP_005258878 (OMIM: 600283) PREDICTED: glutamate r ( 980) 1646 380.1 2.9e-104 XP_011525169 (OMIM: 600283) PREDICTED: glutamate r ( 913) 1640 378.7 7e-104 NP_001287959 (OMIM: 600283) glutamate receptor ion ( 981) 1640 378.7 7.5e-104 >>NP_000818 (OMIM: 138248) glutamate receptor 1 isoform (906 aa) initn: 6035 init1: 6035 opt: 6035 Z-score: 7325.9 bits: 1366.8 E(85289): 0 Smith-Waterman score: 6035; 100.0% identity (100.0% similar) in 906 aa overlap (1-906:1-906) 10 20 30 40 50 60 pF1KB8 MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLPQID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLPQID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 IVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 IVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 FVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 FVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 TEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 NKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 AEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 AEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 RTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 RTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 MLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 LVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 LVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 MCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLES 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 TMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDKLKNKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDKLKNKW 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB8 WYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 WYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB8 GFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSHSSGMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSHSSGMP 850 860 870 880 890 900 pF1KB8 LGATGL :::::: NP_000 LGATGL >>NP_001107655 (OMIM: 138248) glutamate receptor 1 isofo (906 aa) initn: 5976 init1: 5976 opt: 5976 Z-score: 7254.2 bits: 1353.5 E(85289): 0 Smith-Waterman score: 5976; 99.1% identity (99.7% similar) in 906 aa overlap (1-906:1-906) 10 20 30 40 50 60 pF1KB8 MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLPQID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLPQID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 IVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 FVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 TEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 AEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 RTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 MLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGE 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 LVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 MCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQ 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIA 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLES 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 TMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDKLKNKW :::::::::::::::::::::::::::::::::::::.:::::::::.:::.:::::.:: NP_001 TMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKW 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB8 WYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK ::::::::: . ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB8 GFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSHSSGMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSHSSGMP 850 860 870 880 890 900 pF1KB8 LGATGL :::::: NP_001 LGATGL >>NP_001244950 (OMIM: 138248) glutamate receptor 1 isofo (916 aa) initn: 5841 init1: 5841 opt: 5841 Z-score: 7090.1 bits: 1323.1 E(85289): 0 Smith-Waterman score: 5841; 99.7% identity (99.9% similar) in 881 aa overlap (26-906:36-916) 10 20 30 40 50 pF1KB8 MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKL .. ::::::::::::::::::::::::::: NP_001 HLFQPLQLAGGLEWPWSNLLCFLTPVKLHPEVWGLFPNQQSQEHAAFRFALSQLTEPPKL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 LPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPV 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 DTSNQFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DTSNQFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAV 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 NILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGF 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB8 MDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYD 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB8 GVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQF 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB8 NEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTIL 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB8 EDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWN 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB8 GMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPL 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB8 AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSL 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB8 GAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAK 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB8 QTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYA 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB8 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDK 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB8 LKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSE 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB8 SKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSH 850 860 870 880 890 900 900 pF1KB8 SSGMPLGATGL ::::::::::: NP_001 SSGMPLGATGL 910 >>XP_011535937 (OMIM: 138248) PREDICTED: glutamate recep (886 aa) initn: 5782 init1: 5782 opt: 5782 Z-score: 7018.6 bits: 1309.9 E(85289): 0 Smith-Waterman score: 5782; 98.8% identity (99.4% similar) in 882 aa overlap (25-906:5-886) 10 20 30 40 50 60 pF1KB8 MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLPQID : . :::::::::::::::::::::::::::::::: XP_011 MTHVIALWGLFPNQQSQEHAAFRFALSQLTEPPKLLPQID 10 20 30 40 70 80 90 100 110 120 pF1KB8 IVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQ 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 FVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTT 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB8 TEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDL 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB8 NKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVM 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB8 AEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGR 290 300 310 320 330 340 370 380 390 400 410 420 pF1KB8 RTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYV 350 360 370 380 390 400 430 440 450 460 470 480 pF1KB8 MLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGE 410 420 430 440 450 460 490 500 510 520 530 540 pF1KB8 LVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW 470 480 490 500 510 520 550 560 570 580 590 600 pF1KB8 MCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQ 530 540 550 560 570 580 610 620 630 640 650 660 pF1KB8 QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIA 590 600 610 620 630 640 670 680 690 700 710 720 pF1KB8 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLES 650 660 670 680 690 700 730 740 750 760 770 780 pF1KB8 TMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDKLKNKW :::::::::::::::::::::::::::::::::::::.:::::::::.:::.:::::.:: XP_011 TMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKW 710 720 730 740 750 760 790 800 810 820 830 840 pF1KB8 WYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK ::::::::: . ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK 770 780 790 800 810 820 850 860 870 880 890 900 pF1KB8 GFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSHSSGMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSHSSGMP 830 840 850 860 870 880 pF1KB8 LGATGL :::::: XP_011 LGATGL >>NP_001244951 (OMIM: 138248) glutamate receptor 1 isofo (916 aa) initn: 5782 init1: 5782 opt: 5782 Z-score: 7018.4 bits: 1309.9 E(85289): 0 Smith-Waterman score: 5782; 98.8% identity (99.5% similar) in 881 aa overlap (26-906:36-916) 10 20 30 40 50 pF1KB8 MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKL .. ::::::::::::::::::::::::::: NP_001 HLFQPLQLAGGLEWPWSNLLCFLTPVKLHPEVWGLFPNQQSQEHAAFRFALSQLTEPPKL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 LPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPV 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 DTSNQFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DTSNQFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAV 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 NILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGF 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB8 MDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYD 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB8 GVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQF 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB8 NEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTIL 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB8 EDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWN 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB8 GMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPL 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB8 AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSL 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB8 GAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAK 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB8 QTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYA 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB8 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDK ::::::::::::::::::::::::::::::::::::::::::.:::::::::.:::.::: NP_001 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDK 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB8 LKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSE ::.::::::::::: . :::::::::::::::::::::::::::::::::::::::::: NP_001 LKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSE 790 800 810 820 830 840 840 850 860 870 880 890 pF1KB8 SKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSH 850 860 870 880 890 900 900 pF1KB8 SSGMPLGATGL ::::::::::: NP_001 SSGMPLGATGL 910 >>NP_001244952 (OMIM: 138248) glutamate receptor 1 isofo (837 aa) initn: 5567 init1: 5567 opt: 5567 Z-score: 6757.8 bits: 1261.5 E(85289): 0 Smith-Waterman score: 5567; 100.0% identity (100.0% similar) in 837 aa overlap (70-906:1-837) 40 50 60 70 80 90 pF1KB8 AAFRFALSQLTEPPKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTS :::::::::::::::::::::::::::::: NP_001 MTYRFCSQFSKGVYAIFGFYERRTVNMLTS 10 20 30 100 110 120 130 140 150 pF1KB8 FCGALHVCFITPSFPVDTSNQFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FCGALHVCFITPSFPVDTSNQFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQ 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB8 KVLDTAAEKNWQVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVLDTAAEKNWQVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKL 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB8 EKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHT 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB8 RVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQR 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB8 ALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGG 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB8 DNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIV 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB8 SDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIK 400 410 420 430 440 450 520 530 540 550 560 570 pF1KB8 KPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTS 460 470 480 490 500 510 580 590 600 610 620 630 pF1KB8 DQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLT 520 530 540 550 560 570 640 650 660 670 680 690 pF1KB8 VERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRT 580 590 600 610 620 630 700 710 720 730 740 750 pF1KB8 TEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNP 640 650 660 670 680 690 760 770 780 790 800 810 pF1KB8 VNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGL 700 710 720 730 740 750 820 830 840 850 860 870 pF1KB8 AMLVALIEFCYKSRSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AMLVALIEFCYKSRSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVV 760 770 780 790 800 810 880 890 900 pF1KB8 SHDFPKSMQSIPCMSHSSGMPLGATGL ::::::::::::::::::::::::::: NP_001 SHDFPKSMQSIPCMSHSSGMPLGATGL 820 830 >>XP_016864882 (OMIM: 138248) PREDICTED: glutamate recep (837 aa) initn: 5508 init1: 5508 opt: 5508 Z-score: 6686.1 bits: 1248.3 E(85289): 0 Smith-Waterman score: 5508; 99.0% identity (99.6% similar) in 837 aa overlap (70-906:1-837) 40 50 60 70 80 90 pF1KB8 AAFRFALSQLTEPPKLLPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTS :::::::::::::::::::::::::::::: XP_016 MTYRFCSQFSKGVYAIFGFYERRTVNMLTS 10 20 30 100 110 120 130 140 150 pF1KB8 FCGALHVCFITPSFPVDTSNQFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FCGALHVCFITPSFPVDTSNQFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQ 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB8 KVLDTAAEKNWQVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVLDTAAEKNWQVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKL 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB8 EKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHT 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB8 RVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQR 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB8 ALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGG 280 290 300 310 320 330 400 410 420 430 440 450 pF1KB8 DNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIV 340 350 360 370 380 390 460 470 480 490 500 510 pF1KB8 SDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIK 400 410 420 430 440 450 520 530 540 550 560 570 pF1KB8 KPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTS 460 470 480 490 500 510 580 590 600 610 620 630 pF1KB8 DQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLT 520 530 540 550 560 570 640 650 660 670 680 690 pF1KB8 VERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRT 580 590 600 610 620 630 700 710 720 730 740 750 pF1KB8 TEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNP ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.: XP_016 TEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGP 640 650 660 670 680 690 760 770 780 790 800 810 pF1KB8 VNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGL ::::::::.:::.:::::.::::::::::: . :::::::::::::::::::::::::: XP_016 VNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGL 700 710 720 730 740 750 820 830 840 850 860 870 pF1KB8 AMLVALIEFCYKSRSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AMLVALIEFCYKSRSESKRMKGFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVV 760 770 780 790 800 810 880 890 900 pF1KB8 SHDFPKSMQSIPCMSHSSGMPLGATGL ::::::::::::::::::::::::::: XP_016 SHDFPKSMQSIPCMSHSSGMPLGATGL 820 830 >>NP_001244949 (OMIM: 138248) glutamate receptor 1 isofo (811 aa) initn: 5329 init1: 5329 opt: 5329 Z-score: 6468.8 bits: 1208.0 E(85289): 0 Smith-Waterman score: 5329; 99.0% identity (99.6% similar) in 811 aa overlap (96-906:1-811) 70 80 90 100 110 120 pF1KB8 DSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFVLQL :::::::::::::::::::::::::::::: NP_001 MLTSFCGALHVCFITPSFPVDTSNQFVLQL 10 20 30 130 140 150 160 170 180 pF1KB8 RPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTTTEEGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTTTEEGY 40 50 60 70 80 90 190 200 210 220 230 240 pF1KB8 RMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDLNKFKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDLNKFKE 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB8 SGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQ 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB8 SLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYT 220 230 240 250 260 270 370 380 390 400 410 420 pF1KB8 LHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKN 280 290 300 310 320 330 430 440 450 460 470 480 pF1KB8 ANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGR 340 350 360 370 380 390 490 500 510 520 530 540 pF1KB8 ADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVF 400 410 420 430 440 450 550 560 570 580 590 600 pF1KB8 AYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDI 460 470 480 490 500 510 610 620 630 640 650 660 pF1KB8 SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLE 520 530 540 550 560 570 670 680 690 700 710 720 pF1KB8 AGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEY 580 590 600 610 620 630 730 740 750 760 770 780 pF1KB8 IEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDKLKNKWWYDKG ::::::::::::::::::::::::::::::::.:::::::::.:::.:::::.::::::: NP_001 IEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKG 640 650 660 670 680 690 790 800 810 820 830 840 pF1KB8 ECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGFCLI :::: . :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGFCLI 700 710 720 730 740 750 850 860 870 880 890 900 pF1KB8 PQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSHSSGMPLGATG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSHSSGMPLGATG 760 770 780 790 800 810 pF1KB8 L : NP_001 L >>XP_016864881 (OMIM: 138248) PREDICTED: glutamate recep (846 aa) initn: 5118 init1: 5118 opt: 5118 Z-score: 6212.2 bits: 1160.6 E(85289): 0 Smith-Waterman score: 5118; 99.6% identity (99.9% similar) in 770 aa overlap (26-795:36-805) 10 20 30 40 50 pF1KB8 MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKL .. ::::::::::::::::::::::::::: XP_016 HLFQPLQLAGGLEWPWSNLLCFLTPVKLHPEVWGLFPNQQSQEHAAFRFALSQLTEPPKL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 LPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPQIDIVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPV 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 DTSNQFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTSNQFVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAV 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 NILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGF 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB8 MDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDIDLNKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYD 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB8 GVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQF 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB8 NEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTIL 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB8 EDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWN 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB8 GMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPL 490 500 510 520 530 540 540 550 560 570 580 590 pF1KB8 AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSL 550 560 570 580 590 600 600 610 620 630 640 650 pF1KB8 GAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAK 610 620 630 640 650 660 660 670 680 690 700 710 pF1KB8 QTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYA 670 680 690 700 710 720 720 730 740 750 760 770 pF1KB8 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDK 730 740 750 760 770 780 780 790 800 810 820 830 pF1KB8 LKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSE :::::::::::::::::::: XP_016 LKNKWWYDKGECGSGGGDSKVSPRQDKRSEPQQCGRRVLHPDRRTWTSHAGCLNRVLLQI 790 800 810 820 830 840 >>NP_001244948 (OMIM: 138248) glutamate receptor 1 isofo (826 aa) initn: 4982 init1: 4982 opt: 4982 Z-score: 6047.1 bits: 1130.0 E(85289): 0 Smith-Waterman score: 5306; 91.2% identity (91.2% similar) in 906 aa overlap (1-906:1-826) 10 20 30 40 50 60 pF1KB8 MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLPQID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MQHIFAFFCTGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLPQID 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 IVNISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQ ::::::::::::: : NP_001 IVNISDSFEMTYR-C--------------------------------------------- 70 130 140 150 160 170 180 pF1KB8 FVLQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTT :::::::::::::::::::::::::: NP_001 ----------------------------------LSVLQKVLDTAAEKNWQVTAVNILTT 80 90 100 190 200 210 220 230 240 pF1KB8 TEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDL 110 120 130 140 150 160 250 260 270 280 290 300 pF1KB8 NKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NKFKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVM 170 180 190 200 210 220 310 320 330 340 350 360 pF1KB8 AEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEAFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGR 230 240 250 260 270 280 370 380 390 400 410 420 pF1KB8 RTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYV 290 300 310 320 330 340 430 440 450 460 470 480 pF1KB8 MLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLKKNANQFEGNDRYEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGE 350 360 370 380 390 400 490 500 510 520 530 540 pF1KB8 LVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW 410 420 430 440 450 460 550 560 570 580 590 600 pF1KB8 MCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MCIVFAYIGVSVVLFLVSRFSPYEWHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQ 470 480 490 500 510 520 610 620 630 640 650 660 pF1KB8 QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIA 530 540 550 560 570 580 670 680 690 700 710 720 pF1KB8 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLES 590 600 610 620 630 640 730 740 750 760 770 780 pF1KB8 TMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDKLKNKW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRNPVNLAVLKLNEQGLLDKLKNKW 650 660 670 680 690 700 790 800 810 820 830 840 pF1KB8 WYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMK 710 720 730 740 750 760 850 860 870 880 890 900 pF1KB8 GFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSHSSGMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GFCLIPQQSINEAIRTSTLPRNSGAGASSGGSGENGRVVSHDFPKSMQSIPCMSHSSGMP 770 780 790 800 810 820 pF1KB8 LGATGL :::::: NP_001 LGATGL 906 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:41:26 2016 done: Sat Nov 5 16:41:28 2016 Total Scan time: 11.690 Total Display time: 0.320 Function used was FASTA [36.3.4 Apr, 2011]