FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8554, 908 aa 1>>>pF1KB8554 908 - 908 aa - 908 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6178+/-0.000507; mu= 19.4203+/- 0.031 mean_var=78.8003+/-15.946, 0's: 0 Z-trim(108.8): 125 B-trim: 297 in 1/50 Lambda= 0.144481 statistics sampled from 16793 (16937) to 16793 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.552), E-opt: 0.2 (0.199), width: 16 Scan time: 10.030 The best scores are: opt bits E(85289) XP_011514394 (OMIM: 601116) PREDICTED: metabotropi ( 908) 6094 1281.0 0 NP_001120795 (OMIM: 601116) metabotropic glutamate ( 908) 6094 1281.0 0 XP_006716001 (OMIM: 601116) PREDICTED: metabotropi ( 908) 6007 1262.9 0 NP_000836 (OMIM: 601116) metabotropic glutamate re ( 908) 6007 1262.9 0 XP_011514393 (OMIM: 601116) PREDICTED: metabotropi ( 908) 6007 1262.9 0 XP_016867563 (OMIM: 601116) PREDICTED: metabotropi ( 908) 6007 1262.9 0 XP_011514396 (OMIM: 601116) PREDICTED: metabotropi ( 747) 4971 1046.9 0 XP_011514397 (OMIM: 601116) PREDICTED: metabotropi ( 714) 4804 1012.1 0 XP_011514403 (OMIM: 601116) PREDICTED: metabotropi ( 703) 4733 997.3 0 XP_011514404 (OMIM: 601116) PREDICTED: metabotropi ( 703) 4733 997.3 0 NP_000832 (OMIM: 604100) metabotropic glutamate re ( 912) 4669 984.0 0 XP_016866279 (OMIM: 604100) PREDICTED: metabotropi ( 912) 4669 984.0 0 XP_016866280 (OMIM: 604100) PREDICTED: metabotropi ( 912) 4669 984.0 0 XP_016867565 (OMIM: 601116) PREDICTED: metabotropi ( 703) 4646 979.1 0 XP_016867568 (OMIM: 601116) PREDICTED: metabotropi ( 703) 4646 979.1 0 XP_016867564 (OMIM: 601116) PREDICTED: metabotropi ( 703) 4646 979.1 0 XP_016867566 (OMIM: 601116) PREDICTED: metabotropi ( 703) 4646 979.1 0 XP_016867567 (OMIM: 601116) PREDICTED: metabotropi ( 703) 4646 979.1 0 NP_000835 (OMIM: 604101) metabotropic glutamate re ( 915) 4620 973.8 0 NP_870989 (OMIM: 604101) metabotropic glutamate re ( 922) 4615 972.8 0 XP_011514405 (OMIM: 601116) PREDICTED: metabotropi ( 629) 4254 897.4 0 XP_016867569 (OMIM: 601116) PREDICTED: metabotropi ( 629) 4254 897.4 0 NP_001243741 (OMIM: 604100) metabotropic glutamate ( 743) 3936 831.2 0 XP_016866282 (OMIM: 604100) PREDICTED: metabotropi ( 779) 3936 831.2 0 NP_001243742 (OMIM: 604100) metabotropic glutamate ( 779) 3936 831.2 0 XP_016866281 (OMIM: 604100) PREDICTED: metabotropi ( 832) 3932 830.4 0 XP_016861762 (OMIM: 604101) PREDICTED: metabotropi ( 749) 3881 819.7 0 XP_016861761 (OMIM: 604101) PREDICTED: metabotropi ( 756) 3876 818.7 0 NP_000834 (OMIM: 257270,604096) metabotropic gluta ( 877) 3792 801.2 0 XP_011514410 (OMIM: 601116) PREDICTED: metabotropi ( 552) 3521 744.6 3.1e-214 NP_001269776 (OMIM: 604100) metabotropic glutamate ( 604) 3182 673.9 6.2e-193 NP_001243738 (OMIM: 604100) metabotropic glutamate ( 796) 2749 583.8 1.1e-165 NP_001243740 (OMIM: 604100) metabotropic glutamate ( 865) 2749 583.8 1.2e-165 NP_000831 (OMIM: 601115) metabotropic glutamate re ( 879) 2550 542.3 3.8e-153 XP_016861760 (OMIM: 604099) PREDICTED: metabotropi ( 872) 2463 524.2 1.1e-147 NP_000830 (OMIM: 604099) metabotropic glutamate re ( 872) 2463 524.2 1.1e-147 NP_000833 (OMIM: 604102) metabotropic glutamate re (1180) 2155 460.1 2.9e-128 XP_016873116 (OMIM: 604102) PREDICTED: metabotropi (1180) 2155 460.1 2.9e-128 XP_011541094 (OMIM: 604102) PREDICTED: metabotropi (1212) 2155 460.1 3e-128 XP_006718891 (OMIM: 604102) PREDICTED: metabotropi (1212) 2155 460.1 3e-128 NP_001137303 (OMIM: 604102) metabotropic glutamate (1212) 2155 460.1 3e-128 NP_001264995 (OMIM: 604473,614831) metabotropic gl ( 906) 2069 442.1 5.9e-123 XP_016866276 (OMIM: 604473,614831) PREDICTED: meta ( 906) 2069 442.1 5.9e-123 XP_016866274 (OMIM: 604473,614831) PREDICTED: meta ( 906) 2069 442.1 5.9e-123 NP_001264994 (OMIM: 604473,614831) metabotropic gl ( 906) 2069 442.1 5.9e-123 XP_016866275 (OMIM: 604473,614831) PREDICTED: meta ( 906) 2069 442.1 5.9e-123 NP_001264996 (OMIM: 604473,614831) metabotropic gl ( 908) 2069 442.1 5.9e-123 XP_016866272 (OMIM: 604473,614831) PREDICTED: meta (1194) 2069 442.1 7.4e-123 XP_016866273 (OMIM: 604473,614831) PREDICTED: meta (1194) 2069 442.1 7.4e-123 XP_011534084 (OMIM: 604473,614831) PREDICTED: meta (1194) 2069 442.1 7.4e-123 >>XP_011514394 (OMIM: 601116) PREDICTED: metabotropic gl (908 aa) initn: 6094 init1: 6094 opt: 6094 Z-score: 6862.6 bits: 1281.0 E(85289): 0 Smith-Waterman score: 6094; 100.0% identity (100.0% similar) in 908 aa overlap (1-908:1-908) 10 20 30 40 50 60 pF1KB8 MVCEGKRSASCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVHAKGER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVCEGKRSASCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVHAKGER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 EIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 GHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 KDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 KSTEYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSTEYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCER 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 CEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGIIATTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGIIATTF 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 VIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 FSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPH 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 IIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB8 KPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYI 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB8 IIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNSKSSVEFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNSKSSVEFP 850 860 870 880 890 900 pF1KB8 MVKSGSTS :::::::: XP_011 MVKSGSTS >>NP_001120795 (OMIM: 601116) metabotropic glutamate rec (908 aa) initn: 6094 init1: 6094 opt: 6094 Z-score: 6862.6 bits: 1281.0 E(85289): 0 Smith-Waterman score: 6094; 100.0% identity (100.0% similar) in 908 aa overlap (1-908:1-908) 10 20 30 40 50 60 pF1KB8 MVCEGKRSASCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVHAKGER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVCEGKRSASCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVHAKGER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 EIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 GHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 KDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 KSTEYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KSTEYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCER 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 CEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGIIATTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGIIATTF 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 VIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 FSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPH 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 IIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB8 KPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYI 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB8 IIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNSKSSVEFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNSKSSVEFP 850 860 870 880 890 900 pF1KB8 MVKSGSTS :::::::: NP_001 MVKSGSTS >>XP_006716001 (OMIM: 601116) PREDICTED: metabotropic gl (908 aa) initn: 6007 init1: 6007 opt: 6007 Z-score: 6764.6 bits: 1262.9 E(85289): 0 Smith-Waterman score: 6007; 99.7% identity (100.0% similar) in 896 aa overlap (1-896:1-896) 10 20 30 40 50 60 pF1KB8 MVCEGKRSASCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVHAKGER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MVCEGKRSASCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVHAKGER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 EIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 GHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 KDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 KSTEYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KSTEYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCER 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 CEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGIIATTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 CEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGIIATTF 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 VIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 FSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPH 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 IIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB8 KPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYI 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB8 IIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNSKSSVEFP ::::::::::::::::::::::::::::::::::::::::::::::::::::..:. XP_006 IIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNTSSTKTTY 850 860 870 880 890 900 pF1KB8 MVKSGSTS XP_006 ISYSNHSI >>NP_000836 (OMIM: 601116) metabotropic glutamate recept (908 aa) initn: 6007 init1: 6007 opt: 6007 Z-score: 6764.6 bits: 1262.9 E(85289): 0 Smith-Waterman score: 6007; 99.7% identity (100.0% similar) in 896 aa overlap (1-896:1-896) 10 20 30 40 50 60 pF1KB8 MVCEGKRSASCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVHAKGER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MVCEGKRSASCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVHAKGER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 PELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 EIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 EIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 GHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 GHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 KDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 KDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 KSTEYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 KSTEYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCER 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 CEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGIIATTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 CEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGIIATTF 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 VIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 VIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 FSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 FSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPH 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 IIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 IIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB8 KPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 KPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYI 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB8 IIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNSKSSVEFP ::::::::::::::::::::::::::::::::::::::::::::::::::::..:. NP_000 IIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNTSSTKTTY 850 860 870 880 890 900 pF1KB8 MVKSGSTS NP_000 ISYSNHSI >>XP_011514393 (OMIM: 601116) PREDICTED: metabotropic gl (908 aa) initn: 6007 init1: 6007 opt: 6007 Z-score: 6764.6 bits: 1262.9 E(85289): 0 Smith-Waterman score: 6007; 99.7% identity (100.0% similar) in 896 aa overlap (1-896:1-896) 10 20 30 40 50 60 pF1KB8 MVCEGKRSASCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVHAKGER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVCEGKRSASCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVHAKGER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 EIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 GHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 KDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 KSTEYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KSTEYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCER 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 CEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGIIATTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGIIATTF 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 VIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 FSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPH 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 IIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB8 KPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYI 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB8 IIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNSKSSVEFP ::::::::::::::::::::::::::::::::::::::::::::::::::::..:. XP_011 IIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNTSSTKTTY 850 860 870 880 890 900 pF1KB8 MVKSGSTS XP_011 ISYSNHSI >>XP_016867563 (OMIM: 601116) PREDICTED: metabotropic gl (908 aa) initn: 6007 init1: 6007 opt: 6007 Z-score: 6764.6 bits: 1262.9 E(85289): 0 Smith-Waterman score: 6007; 99.7% identity (100.0% similar) in 896 aa overlap (1-896:1-896) 10 20 30 40 50 60 pF1KB8 MVCEGKRSASCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVHAKGER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVCEGKRSASCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVHAKGER 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 EIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 GHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMH 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 KDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB8 KSTEYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KSTEYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCER 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB8 CEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGIIATTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGIIATTF 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB8 VIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMC 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB8 FSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPH 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB8 IIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEA 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB8 KPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYI 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB8 IIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNSKSSVEFP ::::::::::::::::::::::::::::::::::::::::::::::::::::..:. XP_016 IIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNTSSTKTTY 850 860 870 880 890 900 pF1KB8 MVKSGSTS XP_016 ISYSNHSI >>XP_011514396 (OMIM: 601116) PREDICTED: metabotropic gl (747 aa) initn: 4971 init1: 4971 opt: 4971 Z-score: 5598.8 bits: 1046.9 E(85289): 0 Smith-Waterman score: 4971; 100.0% identity (100.0% similar) in 739 aa overlap (170-908:9-747) 140 150 160 170 180 190 pF1KB8 IFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPD :::::::::::::::::::::::::::::: XP_011 MSSENKQEKIPQISYASTAPELSDNTRYDFFSRVVPPD 10 20 30 200 210 220 230 240 250 pF1KB8 SYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRP 40 50 60 70 80 90 260 270 280 290 300 310 pF1KB8 GEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVY 100 110 120 130 140 150 320 330 340 350 360 370 pF1KB8 QQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNS 160 170 180 190 200 210 380 390 400 410 420 430 pF1KB8 HIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDG 220 230 240 250 260 270 440 450 460 470 480 490 pF1KB8 KELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQLHLKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQLHLKV 280 290 300 310 320 330 500 510 520 530 540 550 pF1KB8 EDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLD 340 350 360 370 380 390 560 570 580 590 600 610 pF1KB8 QRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGR 400 410 420 430 440 450 620 630 640 650 660 670 pF1KB8 ELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMCFSYAALLTKTNRIHRIFEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMCFSYAALLTKTNRIHRIFEQ 460 470 480 490 500 510 680 690 700 710 720 730 pF1KB8 GKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGEQRTLDPEKARGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGEQRTLDPEKARGV 520 530 540 550 560 570 740 750 760 770 780 790 pF1KB8 LKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIP 580 590 600 610 620 630 800 810 820 830 840 850 pF1KB8 IFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQKRKRSFKAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQKRKRSFKAV 640 650 660 670 680 690 860 870 880 890 900 pF1KB8 VTAATMQSKLIQKGNDRPNGEVKSELCESLETNSKSSVEFPMVKSGSTS ::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTAATMQSKLIQKGNDRPNGEVKSELCESLETNSKSSVEFPMVKSGSTS 700 710 720 730 740 >>XP_011514397 (OMIM: 601116) PREDICTED: metabotropic gl (714 aa) initn: 4804 init1: 4804 opt: 4804 Z-score: 5410.9 bits: 1012.1 E(85289): 0 Smith-Waterman score: 4804; 99.9% identity (100.0% similar) in 714 aa overlap (195-908:1-714) 170 180 190 200 210 220 pF1KB8 ILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASE .::::::::::::::::::::::::::::: XP_011 MVPPDSYQAQAMVDIVTALGWNYVSTLASE 10 20 30 230 240 250 260 270 280 pF1KB8 GNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANE 40 50 60 70 80 90 290 300 310 320 330 340 pF1KB8 DDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRY 100 110 120 130 140 150 350 360 370 380 390 400 pF1KB8 FRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQF 160 170 180 190 200 210 410 420 430 440 450 460 pF1KB8 VIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNEN 220 230 240 250 260 270 470 480 490 500 510 520 pF1KB8 GDAPGRYDIFQYQITNKSTEYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDAPGRYDIFQYQITNKSTEYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGE 280 290 300 310 320 330 530 540 550 560 570 580 pF1KB8 RKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWA 340 350 360 370 380 390 590 600 610 620 630 640 pF1KB8 VVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPD 400 410 420 430 440 450 650 660 670 680 690 700 pF1KB8 TIICSFRRVFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TIICSFRRVFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLIS 460 470 480 490 500 510 710 720 730 740 750 760 pF1KB8 VQLLGVFVWFVVDPPHIIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VQLLGVFVWFVVDPPHIIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCT 520 530 540 550 560 570 770 780 790 800 810 820 pF1KB8 VYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSL 580 590 600 610 620 630 830 840 850 860 870 880 pF1KB8 SASVSLGMLYMPKVYIIIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SASVSLGMLYMPKVYIIIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSE 640 650 660 670 680 690 890 900 pF1KB8 LCESLETNSKSSVEFPMVKSGSTS :::::::::::::::::::::::: XP_011 LCESLETNSKSSVEFPMVKSGSTS 700 710 >>XP_011514403 (OMIM: 601116) PREDICTED: metabotropic gl (703 aa) initn: 4733 init1: 4733 opt: 4733 Z-score: 5331.0 bits: 997.3 E(85289): 0 Smith-Waterman score: 4733; 100.0% identity (100.0% similar) in 703 aa overlap (206-908:1-703) 180 190 200 210 220 230 pF1KB8 YASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAF :::::::::::::::::::::::::::::: XP_011 MVDIVTALGWNYVSTLASEGNYGESGVEAF 10 20 30 240 250 260 270 280 290 pF1KB8 TQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAK 40 50 60 70 80 90 300 310 320 330 340 350 pF1KB8 KLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRR 100 110 120 130 140 150 360 370 380 390 400 410 pF1KB8 NVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYA 160 170 180 190 200 210 420 430 440 450 460 470 pF1KB8 LHNMHKDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LHNMHKDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQ 220 230 240 250 260 270 480 490 500 510 520 530 pF1KB8 YQITNKSTEYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YQITNKSTEYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCC 280 290 300 310 320 330 540 550 560 570 580 590 pF1KB8 WHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGI 340 350 360 370 380 390 600 610 620 630 640 650 pF1KB8 IATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFL 400 410 420 430 440 450 660 670 680 690 700 710 pF1KB8 GLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFV 460 470 480 490 500 510 720 730 740 750 760 770 pF1KB8 VDPPHIIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VDPPHIIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPE 520 530 540 550 560 570 780 790 800 810 820 830 pF1KB8 TFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYM 580 590 600 610 620 630 840 850 860 870 880 890 pF1KB8 PKVYIIIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNSKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKVYIIIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNSKS 640 650 660 670 680 690 900 pF1KB8 SVEFPMVKSGSTS ::::::::::::: XP_011 SVEFPMVKSGSTS 700 >>XP_011514404 (OMIM: 601116) PREDICTED: metabotropic gl (703 aa) initn: 4733 init1: 4733 opt: 4733 Z-score: 5331.0 bits: 997.3 E(85289): 0 Smith-Waterman score: 4733; 100.0% identity (100.0% similar) in 703 aa overlap (206-908:1-703) 180 190 200 210 220 230 pF1KB8 YASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAF :::::::::::::::::::::::::::::: XP_011 MVDIVTALGWNYVSTLASEGNYGESGVEAF 10 20 30 240 250 260 270 280 290 pF1KB8 TQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAK 40 50 60 70 80 90 300 310 320 330 340 350 pF1KB8 KLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRR 100 110 120 130 140 150 360 370 380 390 400 410 pF1KB8 NVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYA 160 170 180 190 200 210 420 430 440 450 460 470 pF1KB8 LHNMHKDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LHNMHKDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQ 220 230 240 250 260 270 480 490 500 510 520 530 pF1KB8 YQITNKSTEYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YQITNKSTEYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCC 280 290 300 310 320 330 540 550 560 570 580 590 pF1KB8 WHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGI 340 350 360 370 380 390 600 610 620 630 640 650 pF1KB8 IATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFL 400 410 420 430 440 450 660 670 680 690 700 710 pF1KB8 GLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFV 460 470 480 490 500 510 720 730 740 750 760 770 pF1KB8 VDPPHIIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VDPPHIIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPE 520 530 540 550 560 570 780 790 800 810 820 830 pF1KB8 TFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYM 580 590 600 610 620 630 840 850 860 870 880 890 pF1KB8 PKVYIIIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNSKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PKVYIIIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNSKS 640 650 660 670 680 690 900 pF1KB8 SVEFPMVKSGSTS ::::::::::::: XP_011 SVEFPMVKSGSTS 700 908 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:42:16 2016 done: Sat Nov 5 16:42:17 2016 Total Scan time: 10.030 Total Display time: 0.250 Function used was FASTA [36.3.4 Apr, 2011]