Result of FASTA (omim) for
pF1KB8567
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8567, 398 aa
1>>>pF1KB8567 398 - 398 aa - 398 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4124+/-0.000435; mu= 18.2539+/- 0.027
mean_var=90.7987+/-17.790, 0's: 0 Z-trim(111.4): 45 B-trim: 940 in 2/54
Lambda= 0.134597
statistics sampled from 19931 (19976) to 19931 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.603), E-opt: 0.2 (0.234), width: 16
Scan time: 7.830
The best scores are: opt bits E(85289)
NP_004692 (OMIM: 602755) G2/mitotic-specific cycli ( 398) 2564 508.2 1.4e-143
NP_114172 (OMIM: 123836) G2/mitotic-specific cycli ( 433) 1311 265.0 2.5e-70
XP_011533596 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421) 617 130.2 9.2e-30
XP_011533597 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421) 617 130.2 9.2e-30
NP_001104517 (OMIM: 604036) cyclin-A1 isoform c [H ( 421) 617 130.2 9.2e-30
XP_011533598 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421) 617 130.2 9.2e-30
NP_001104516 (OMIM: 604036) cyclin-A1 isoform c [H ( 421) 617 130.2 9.2e-30
NP_001104515 (OMIM: 604036) cyclin-A1 isoform b [H ( 464) 617 130.2 9.8e-30
NP_003905 (OMIM: 604036) cyclin-A1 isoform a [Homo ( 465) 617 130.2 9.9e-30
XP_016885405 (OMIM: 300456) PREDICTED: G2/mitotic- (1403) 543 116.3 4.7e-25
XP_016885404 (OMIM: 300456) PREDICTED: G2/mitotic- (1404) 543 116.3 4.7e-25
XP_016885403 (OMIM: 300456) PREDICTED: G2/mitotic- (1404) 543 116.3 4.7e-25
XP_016885402 (OMIM: 300456) PREDICTED: G2/mitotic- (1404) 543 116.3 4.7e-25
XP_016885407 (OMIM: 300456) PREDICTED: G2/mitotic- (1395) 542 116.1 5.3e-25
NP_149020 (OMIM: 300456) G2/mitotic-specific cycli (1395) 542 116.1 5.3e-25
XP_016885406 (OMIM: 300456) PREDICTED: G2/mitotic- (1396) 542 116.1 5.3e-25
NP_001228 (OMIM: 123835) cyclin-A2 [Homo sapiens] ( 432) 534 114.1 6.6e-25
NP_391990 (OMIM: 300456) G2/mitotic-specific cycli ( 291) 407 89.3 1.3e-17
NP_066970 (OMIM: 607752,615872) cyclin-O [Homo sap ( 350) 320 72.5 1.8e-12
XP_011515668 (OMIM: 603775) PREDICTED: G1/S-specif ( 288) 307 69.9 9.2e-12
XP_016869447 (OMIM: 603775) PREDICTED: G1/S-specif ( 404) 307 70.0 1.2e-11
NP_477097 (OMIM: 603775) G1/S-specific cyclin-E2 [ ( 404) 307 70.0 1.2e-11
XP_016869446 (OMIM: 603775) PREDICTED: G1/S-specif ( 404) 307 70.0 1.2e-11
XP_016869448 (OMIM: 603775) PREDICTED: G1/S-specif ( 404) 307 70.0 1.2e-11
XP_011525742 (OMIM: 123837) PREDICTED: G1/S-specif ( 407) 305 69.6 1.5e-11
NP_001229 (OMIM: 123837) G1/S-specific cyclin-E1 i ( 410) 304 69.4 1.8e-11
NP_001309191 (OMIM: 123837) G1/S-specific cyclin-E ( 395) 297 68.0 4.4e-11
NP_001309188 (OMIM: 123837) G1/S-specific cyclin-E ( 365) 286 65.9 1.8e-10
NP_001751 (OMIM: 123834) G1/S-specific cyclin-D3 i ( 292) 269 62.5 1.5e-09
NP_001752 (OMIM: 600227) cyclin-F isoform 1 [Homo ( 786) 274 63.8 1.6e-09
XP_016879311 (OMIM: 600227) PREDICTED: cyclin-F is ( 867) 274 63.9 1.7e-09
NP_001310467 (OMIM: 600227) cyclin-F isoform 2 [Ho ( 478) 265 61.9 3.8e-09
NP_444284 (OMIM: 168461,193300,254500) G1/S-specif ( 295) 260 60.7 5.2e-09
XP_011513273 (OMIM: 123834) PREDICTED: G1/S-specif ( 276) 236 56.0 1.3e-07
NP_001750 (OMIM: 123833,615938) G1/S-specific cycl ( 289) 231 55.1 2.6e-07
NP_001274356 (OMIM: 123834) G1/S-specific cyclin-D ( 242) 215 51.9 1.9e-06
NP_001129489 (OMIM: 123834) G1/S-specific cyclin-D ( 211) 205 49.9 6.7e-06
XP_011530701 (OMIM: 603203) PREDICTED: cyclin-G2 i ( 344) 177 44.7 0.00042
XP_011530700 (OMIM: 603203) PREDICTED: cyclin-G2 i ( 344) 177 44.7 0.00042
NP_004345 (OMIM: 603203) cyclin-G2 [Homo sapiens] ( 344) 177 44.7 0.00042
XP_011513274 (OMIM: 123834) PREDICTED: G1/S-specif ( 195) 172 43.5 0.00054
NP_004051 (OMIM: 601578) cyclin-G1 [Homo sapiens] ( 295) 159 41.1 0.0042
NP_954854 (OMIM: 601578) cyclin-G1 [Homo sapiens] ( 295) 159 41.1 0.0042
>>NP_004692 (OMIM: 602755) G2/mitotic-specific cyclin-B2 (398 aa)
initn: 2564 init1: 2564 opt: 2564 Z-score: 2698.9 bits: 508.2 E(85289): 1.4e-143
Smith-Waterman score: 2564; 100.0% identity (100.0% similar) in 398 aa overlap (1-398:1-398)
10 20 30 40 50 60
pF1KB8 MALLRRPTVSSDLENIDTGVNSKVKSHVTIRRTVLEEIGNRVTTRAAQVAKKAQNTKVPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MALLRRPTVSSDLENIDTGVNSKVKSHVTIRRTVLEEIGNRVTTRAAQVAKKAQNTKVPV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 QPTKTTNVNKQLKPTASVKPVQMEKLAPKGPSPTPEDVSMKEENLCQAFSDALLCKIEDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QPTKTTNVNKQLKPTASVKPVQMEKLAPKGPSPTPEDVSMKEENLCQAFSDALLCKIEDI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 DNEDWENPQLCSDYVKDIYQYLRQLEVLQSINPHFLDGRDINGRMRAILVDWLVQVHSKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DNEDWENPQLCSDYVKDIYQYLRQLEVLQSINPHFLDGRDINGRMRAILVDWLVQVHSKF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 RLLQETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RLLQETLYMCVGIMDRFLQVQPVSRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 YTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLIDYDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YTSSQIREMETLILKELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLIDYDM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 VHYHPSKVAAAASCLSQKVLGQGKWNLKQQYYTGYTENEVLEVMQHMAKNVVKVNENLTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VHYHPSKVAAAASCLSQKVLGQGKWNLKQQYYTGYTENEVLEVMQHMAKNVVKVNENLTK
310 320 330 340 350 360
370 380 390
pF1KB8 FIAIKNKYASSKLLKISMIPQLNSKAVKDLASPLIGRS
::::::::::::::::::::::::::::::::::::::
NP_004 FIAIKNKYASSKLLKISMIPQLNSKAVKDLASPLIGRS
370 380 390
>>NP_114172 (OMIM: 123836) G2/mitotic-specific cyclin-B1 (433 aa)
initn: 1198 init1: 1198 opt: 1311 Z-score: 1383.5 bits: 265.0 E(85289): 2.5e-70
Smith-Waterman score: 1311; 52.7% identity (77.2% similar) in 395 aa overlap (6-391:40-427)
10 20 30
pF1KB8 MALLRRPTVSSDLENIDTGVNSKVKSHVTIRRTVL
:: .. : .: . :. ...... ... .
NP_114 KINAENKAKINMAGAKRVPTAPAATSKPGLRPRTA--LGDIGNKVSEQLQAKMPMKKEAK
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB8 EEIGNRVTTRAAQVAKKAQNTKVPVQ-PTKTTNVNKQLKPTASVKPVQMEKLAPKG----
..: . .. : . :::. :. ... . .: .::. :::.:.
NP_114 PSATGKVIDK--KLPKPLE--KVPMLVPVPVSEPVPEPEPEPEPEPVKEEKLSPEPILVD
70 80 90 100 110 120
100 110 120 130 140
pF1KB8 -PSPTPEDVSM---KEENLCQAFSDALLCKIEDIDNEDWENPQLCSDYVKDIYQYLRQLE
::.: ..: ::.:::::::..: ..:.: :: .:.:::.:::::: ::::::
NP_114 TASPSPMETSGCAPAEEDLCQAFSDVILA-VNDVDAEDGADPNLCSEYVKDIYAYLRQLE
130 140 150 160 170 180
150 160 170 180 190 200
pF1KB8 VLQSINPHFLDGRDINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQVQPVSRK
:.. :..: ::...: :::::.::::::. ::::::::.:: :.:.:::.: . : .:
NP_114 EEQAVRPKYLLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFMQNNCVPKK
190 200 210 220 230 240
210 220 230 240 250 260
pF1KB8 KLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFELGRPLP
:::::.::...:::::::. :.: ::...:::.::. :::.:: ::. :.: ::::::
NP_114 MLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNFGLGRPLP
250 260 270 280 290 300
270 280 290 300 310 320
pF1KB8 LHFLRRASKAGEVDVEQHTLAKYLMELTLIDYDMVHYHPSKVAAAASCLSQKVLGQGKWN
::::::::: ::::::::::::::::::..::::::. ::..::.: ::. :.: .:.:.
NP_114 LHFLRRASKIGEVDVEQHTLAKYLMELTMLDYDMVHFPPSQIAAGAFCLALKILDNGEWT
310 320 330 340 350 360
330 340 350 360 370 380
pF1KB8 LKQQYYTGYTENEVLEVMQHMAKNVVKVNENLTKFIAIKNKYASSKLLKISMIPQLNSKA
:.: .:::. .: ::::.::::: ::..::: ...:::::.:: ::: .:::::
NP_114 PTLQHYLSYTEESLLPVMQHLAKNVVMVNQGLTKHMTVKNKYATSKHAKISTLPQLNSAL
370 380 390 400 410 420
390
pF1KB8 VKDLASPLIGRS
:.:::
NP_114 VQDLAKAVAKV
430
>>XP_011533596 (OMIM: 604036) PREDICTED: cyclin-A1 isofo (421 aa)
initn: 587 init1: 429 opt: 617 Z-score: 655.3 bits: 130.2 E(85289): 9.2e-30
Smith-Waterman score: 617; 39.6% identity (71.1% similar) in 270 aa overlap (112-379:146-412)
90 100 110 120 130 140
pF1KB8 QMEKLAPKGPSPTPEDVSMKEENLCQAFSDALLCKIEDIDNEDWENPQLCSDYVKDIYQY
.:: . :::.. . .. ..:...::::
XP_011 DVYEVDTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINV-TEYAEEIYQY
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB8 LRQLEVLQSINPHFLDGR-DINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQV
::. :. . . :.. . ::. ::.:::::::.: ...: ::::. :...::::.
XP_011 LREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSC
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB8 QPVSRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFE
. : : :::::: .:.::::::::.. :....::::::..::. :. .:: :.:: : :.
XP_011 MSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFD
240 250 260 270 280 290
270 280 290 300 310
pF1KB8 LGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLIDYD-MVHYHPSKVAAAASCLSQKV
: : .:: . . : :. ..::::. ::.:.. : ...: :: .:::: ::.. .
XP_011 LTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYT
300 310 320 330 340 350
320 330 340 350 360 370
pF1KB8 LGQGKWNLKQQYYTGYTENEVLEVMQHMAKNVVKVNENLTKFIAIKNKYASSKLLKISMI
... : .:::. .:.. .... : . . . . ::..:: .:: : .:..
XP_011 VNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQ--AIREKYKASKYLCVSLM
360 370 380 390 400 410
380 390
pF1KB8 PQLNSKAVKDLASPLIGRS
XP_011 EPPAVLLLQ
420
>>XP_011533597 (OMIM: 604036) PREDICTED: cyclin-A1 isofo (421 aa)
initn: 587 init1: 429 opt: 617 Z-score: 655.3 bits: 130.2 E(85289): 9.2e-30
Smith-Waterman score: 617; 39.6% identity (71.1% similar) in 270 aa overlap (112-379:146-412)
90 100 110 120 130 140
pF1KB8 QMEKLAPKGPSPTPEDVSMKEENLCQAFSDALLCKIEDIDNEDWENPQLCSDYVKDIYQY
.:: . :::.. . .. ..:...::::
XP_011 DVYEVDTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINV-TEYAEEIYQY
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB8 LRQLEVLQSINPHFLDGR-DINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQV
::. :. . . :.. . ::. ::.:::::::.: ...: ::::. :...::::.
XP_011 LREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSC
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB8 QPVSRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFE
. : : :::::: .:.::::::::.. :....::::::..::. :. .:: :.:: : :.
XP_011 MSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFD
240 250 260 270 280 290
270 280 290 300 310
pF1KB8 LGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLIDYD-MVHYHPSKVAAAASCLSQKV
: : .:: . . : :. ..::::. ::.:.. : ...: :: .:::: ::.. .
XP_011 LTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYT
300 310 320 330 340 350
320 330 340 350 360 370
pF1KB8 LGQGKWNLKQQYYTGYTENEVLEVMQHMAKNVVKVNENLTKFIAIKNKYASSKLLKISMI
... : .:::. .:.. .... : . . . . ::..:: .:: : .:..
XP_011 VNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQ--AIREKYKASKYLCVSLM
360 370 380 390 400 410
380 390
pF1KB8 PQLNSKAVKDLASPLIGRS
XP_011 EPPAVLLLQ
420
>>NP_001104517 (OMIM: 604036) cyclin-A1 isoform c [Homo (421 aa)
initn: 587 init1: 429 opt: 617 Z-score: 655.3 bits: 130.2 E(85289): 9.2e-30
Smith-Waterman score: 617; 39.6% identity (71.1% similar) in 270 aa overlap (112-379:146-412)
90 100 110 120 130 140
pF1KB8 QMEKLAPKGPSPTPEDVSMKEENLCQAFSDALLCKIEDIDNEDWENPQLCSDYVKDIYQY
.:: . :::.. . .. ..:...::::
NP_001 DVYEVDTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINV-TEYAEEIYQY
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB8 LRQLEVLQSINPHFLDGR-DINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQV
::. :. . . :.. . ::. ::.:::::::.: ...: ::::. :...::::.
NP_001 LREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSC
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB8 QPVSRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFE
. : : :::::: .:.::::::::.. :....::::::..::. :. .:: :.:: : :.
NP_001 MSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFD
240 250 260 270 280 290
270 280 290 300 310
pF1KB8 LGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLIDYD-MVHYHPSKVAAAASCLSQKV
: : .:: . . : :. ..::::. ::.:.. : ...: :: .:::: ::.. .
NP_001 LTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYT
300 310 320 330 340 350
320 330 340 350 360 370
pF1KB8 LGQGKWNLKQQYYTGYTENEVLEVMQHMAKNVVKVNENLTKFIAIKNKYASSKLLKISMI
... : .:::. .:.. .... : . . . . ::..:: .:: : .:..
NP_001 VNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQ--AIREKYKASKYLCVSLM
360 370 380 390 400 410
380 390
pF1KB8 PQLNSKAVKDLASPLIGRS
NP_001 EPPAVLLLQ
420
>>XP_011533598 (OMIM: 604036) PREDICTED: cyclin-A1 isofo (421 aa)
initn: 587 init1: 429 opt: 617 Z-score: 655.3 bits: 130.2 E(85289): 9.2e-30
Smith-Waterman score: 617; 39.6% identity (71.1% similar) in 270 aa overlap (112-379:146-412)
90 100 110 120 130 140
pF1KB8 QMEKLAPKGPSPTPEDVSMKEENLCQAFSDALLCKIEDIDNEDWENPQLCSDYVKDIYQY
.:: . :::.. . .. ..:...::::
XP_011 DVYEVDTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINV-TEYAEEIYQY
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB8 LRQLEVLQSINPHFLDGR-DINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQV
::. :. . . :.. . ::. ::.:::::::.: ...: ::::. :...::::.
XP_011 LREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSC
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB8 QPVSRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFE
. : : :::::: .:.::::::::.. :....::::::..::. :. .:: :.:: : :.
XP_011 MSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFD
240 250 260 270 280 290
270 280 290 300 310
pF1KB8 LGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLIDYD-MVHYHPSKVAAAASCLSQKV
: : .:: . . : :. ..::::. ::.:.. : ...: :: .:::: ::.. .
XP_011 LTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYT
300 310 320 330 340 350
320 330 340 350 360 370
pF1KB8 LGQGKWNLKQQYYTGYTENEVLEVMQHMAKNVVKVNENLTKFIAIKNKYASSKLLKISMI
... : .:::. .:.. .... : . . . . ::..:: .:: : .:..
XP_011 VNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQ--AIREKYKASKYLCVSLM
360 370 380 390 400 410
380 390
pF1KB8 PQLNSKAVKDLASPLIGRS
XP_011 EPPAVLLLQ
420
>>NP_001104516 (OMIM: 604036) cyclin-A1 isoform c [Homo (421 aa)
initn: 587 init1: 429 opt: 617 Z-score: 655.3 bits: 130.2 E(85289): 9.2e-30
Smith-Waterman score: 617; 39.6% identity (71.1% similar) in 270 aa overlap (112-379:146-412)
90 100 110 120 130 140
pF1KB8 QMEKLAPKGPSPTPEDVSMKEENLCQAFSDALLCKIEDIDNEDWENPQLCSDYVKDIYQY
.:: . :::.. . .. ..:...::::
NP_001 DVYEVDTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINV-TEYAEEIYQY
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB8 LRQLEVLQSINPHFLDGR-DINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQV
::. :. . . :.. . ::. ::.:::::::.: ...: ::::. :...::::.
NP_001 LREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSC
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB8 QPVSRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFE
. : : :::::: .:.::::::::.. :....::::::..::. :. .:: :.:: : :.
NP_001 MSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFD
240 250 260 270 280 290
270 280 290 300 310
pF1KB8 LGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLIDYD-MVHYHPSKVAAAASCLSQKV
: : .:: . . : :. ..::::. ::.:.. : ...: :: .:::: ::.. .
NP_001 LTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYT
300 310 320 330 340 350
320 330 340 350 360 370
pF1KB8 LGQGKWNLKQQYYTGYTENEVLEVMQHMAKNVVKVNENLTKFIAIKNKYASSKLLKISMI
... : .:::. .:.. .... : . . . . ::..:: .:: : .:..
NP_001 VNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQ--AIREKYKASKYLCVSLM
360 370 380 390 400 410
380 390
pF1KB8 PQLNSKAVKDLASPLIGRS
NP_001 EPPAVLLLQ
420
>>NP_001104515 (OMIM: 604036) cyclin-A1 isoform b [Homo (464 aa)
initn: 587 init1: 429 opt: 617 Z-score: 654.8 bits: 130.2 E(85289): 9.8e-30
Smith-Waterman score: 617; 39.6% identity (71.1% similar) in 270 aa overlap (112-379:189-455)
90 100 110 120 130 140
pF1KB8 QMEKLAPKGPSPTPEDVSMKEENLCQAFSDALLCKIEDIDNEDWENPQLCSDYVKDIYQY
.:: . :::.. . .. ..:...::::
NP_001 DVYEVDTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINV-TEYAEEIYQY
160 170 180 190 200 210
150 160 170 180 190 200
pF1KB8 LRQLEVLQSINPHFLDGR-DINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQV
::. :. . . :.. . ::. ::.:::::::.: ...: ::::. :...::::.
NP_001 LREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSC
220 230 240 250 260 270
210 220 230 240 250 260
pF1KB8 QPVSRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFE
. : : :::::: .:.::::::::.. :....::::::..::. :. .:: :.:: : :.
NP_001 MSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFD
280 290 300 310 320 330
270 280 290 300 310
pF1KB8 LGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLIDYD-MVHYHPSKVAAAASCLSQKV
: : .:: . . : :. ..::::. ::.:.. : ...: :: .:::: ::.. .
NP_001 LTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYT
340 350 360 370 380 390
320 330 340 350 360 370
pF1KB8 LGQGKWNLKQQYYTGYTENEVLEVMQHMAKNVVKVNENLTKFIAIKNKYASSKLLKISMI
... : .:::. .:.. .... : . . . . ::..:: .:: : .:..
NP_001 VNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQ--AIREKYKASKYLCVSLM
400 410 420 430 440 450
380 390
pF1KB8 PQLNSKAVKDLASPLIGRS
NP_001 EPPAVLLLQ
460
>>NP_003905 (OMIM: 604036) cyclin-A1 isoform a [Homo sap (465 aa)
initn: 587 init1: 429 opt: 617 Z-score: 654.8 bits: 130.2 E(85289): 9.9e-30
Smith-Waterman score: 617; 39.6% identity (71.1% similar) in 270 aa overlap (112-379:190-456)
90 100 110 120 130 140
pF1KB8 QMEKLAPKGPSPTPEDVSMKEENLCQAFSDALLCKIEDIDNEDWENPQLCSDYVKDIYQY
.:: . :::.. . .. ..:...::::
NP_003 DVYEVDTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINV-TEYAEEIYQY
160 170 180 190 200 210
150 160 170 180 190 200
pF1KB8 LRQLEVLQSINPHFLDGR-DINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFLQV
::. :. . . :.. . ::. ::.:::::::.: ...: ::::. :...::::.
NP_003 LREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSC
220 230 240 250 260 270
210 220 230 240 250 260
pF1KB8 QPVSRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKELKFE
. : : :::::: .:.::::::::.. :....::::::..::. :. .:: :.:: : :.
NP_003 MSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFD
280 290 300 310 320 330
270 280 290 300 310
pF1KB8 LGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLIDYD-MVHYHPSKVAAAASCLSQKV
: : .:: . . : :. ..::::. ::.:.. : ...: :: .:::: ::.. .
NP_003 LTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYT
340 350 360 370 380 390
320 330 340 350 360 370
pF1KB8 LGQGKWNLKQQYYTGYTENEVLEVMQHMAKNVVKVNENLTKFIAIKNKYASSKLLKISMI
... : .:::. .:.. .... : . . . . ::..:: .:: : .:..
NP_003 VNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQ--AIREKYKASKYLCVSLM
400 410 420 430 440 450
380 390
pF1KB8 PQLNSKAVKDLASPLIGRS
NP_003 EPPAVLLLQ
460
>>XP_016885405 (OMIM: 300456) PREDICTED: G2/mitotic-spec (1403 aa)
initn: 487 init1: 458 opt: 543 Z-score: 570.9 bits: 116.3 E(85289): 4.7e-25
Smith-Waterman score: 548; 29.4% identity (62.3% similar) in 398 aa overlap (1-383:1013-1384)
10 20
pF1KB8 MALLRRPTVSSDL---ENIDTGVNSKVKSH
..: ..::....: : . . :
XP_016 ESITSKSSIATMTSVGKSGTINEAFLFEDMITLNEKPTTGKELSFKEPLALQESPTCKED
990 1000 1010 1020 1030 1040
30 40 50 60 70 80
pF1KB8 VTIRRTVLEEIGNR---VTTRAAQVAKKAQ-NTKVPVQPTKTTNVNKQLKPTASVKPVQM
. .. .. .::. .: ....:.. : . : ..::. .. . .:: :::.
XP_016 TFLETFLIPQIGTSPYVFSTTPESITEKSSIATMTSVGKSRTTTESSACE-SASDKPVSP
1050 1060 1070 1080 1090 1100
90 100 110 120 130 140
pF1KB8 EKLAPKGPSPTPEDVSMKEENLCQAFSDALLCKIEDIDNEDWENPQLCSDYVKDIYQYLR
. :: ::.... .: ::: :: .:.. :.:.:..:..
XP_016 QA---KG---TPKEITPRE----------------DID-EDSSDPSFNPMYAKEIFSYMK
1110 1120 1130
150 160 170 180 190
pF1KB8 QLEVLQSINPH-------FLDGR-DINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMD
. :. .. . : ... . .:.. ::::::::::.:. .:.. .::::. : ..:
XP_016 EREIEETAQSHEQFILTDYMNRQIEITSDMRAILVDWLVEVQVSFEMTHETLYLAVKLVD
1140 1150 1160 1170 1180 1190
200 210 220 230 240 250
pF1KB8 RFLQVQPVSRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILK
.:. .. ::::.: ::...:.:.:: :: ..::::: :. : :.. :: ::.
XP_016 LYLMKAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDDNYQRSEVLSMEINILN
1200 1210 1220 1230 1240 1250
260 270 280 290 300 310
pF1KB8 ELKFELGRPLPLHFLRRASKAGEVDVEQHTLAKYLMELTLIDYDMVHYHPSKVAAAASCL
:: ... :. ::::: .. ..... ::..:. :.:: .: .:. . ::.:::. :
XP_016 VLKCDINIPIAYHFLRRYARCIHTNMKTLTLSRYICEMTLQEYHYVQEKASKLAAASLLL
1260 1270 1280 1290 1300 1310
320 330 340 350 360 370
pF1KB8 SQKVLGQGKWNLKQQYYTGYTENEVLEVMQHMAKNVVKVNENLTKFIAIKNKYASSKLLK
. . : : ..:.::. .:. ..... : .. . . : :. ::. ...
XP_016 ALYMKKLGYWVPFLEHYSGYSISELHPLVRQLNKLLTFSSYDSLK--AVYYKYSHPVFFE
1320 1330 1340 1350 1360 1370
380 390
pF1KB8 ISMIPQLNSKAVKDLASPLIGRS
.. :: :.
XP_016 VAKIPALDMLKLEEILNCDCEAQGLVL
1380 1390 1400
398 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 19:53:05 2016 done: Sat Nov 5 19:53:06 2016
Total Scan time: 7.830 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]