Result of FASTA (omim) for
pF1KB8574
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8574, 781 aa
1>>>pF1KB8574 781 - 781 aa - 781 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.0724+/-0.000388; mu= 8.9006+/- 0.024
mean_var=154.7990+/-30.798, 0's: 0 Z-trim(118.4): 48 B-trim: 615 in 1/51
Lambda= 0.103084
statistics sampled from 31345 (31393) to 31345 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.368), width: 16
Scan time: 11.810
The best scores are: opt bits E(85289)
NP_001269618 (OMIM: 607693,609698) selenocysteine ( 781) 5131 775.2 0
XP_006717345 (OMIM: 607693,609698) PREDICTED: sele ( 781) 5131 775.2 0
NP_001269619 (OMIM: 607693,609698) selenocysteine ( 786) 4944 747.4 5.2e-215
XP_011517302 (OMIM: 607693,609698) PREDICTED: sele ( 786) 4944 747.4 5.2e-215
NP_076982 (OMIM: 607693,609698) selenocysteine ins ( 854) 4944 747.5 5.6e-215
NP_001269617 (OMIM: 607693,609698) selenocysteine ( 853) 4926 744.8 3.6e-214
XP_005252259 (OMIM: 607693,609698) PREDICTED: sele ( 555) 3630 551.9 2.6e-156
XP_016870614 (OMIM: 607693,609698) PREDICTED: sele ( 559) 3594 546.6 1.1e-154
XP_011517305 (OMIM: 607693,609698) PREDICTED: sele ( 747) 3446 524.6 5.8e-148
XP_005252253 (OMIM: 607693,609698) PREDICTED: sele ( 815) 3446 524.7 6.2e-148
XP_011517304 (OMIM: 607693,609698) PREDICTED: sele ( 748) 3445 524.5 6.4e-148
XP_016870612 (OMIM: 607693,609698) PREDICTED: sele ( 816) 3445 524.5 6.9e-148
XP_011517303 (OMIM: 607693,609698) PREDICTED: sele ( 756) 2791 427.2 1.2e-118
XP_016870613 (OMIM: 607693,609698) PREDICTED: sele ( 785) 2791 427.2 1.3e-118
XP_016870611 (OMIM: 607693,609698) PREDICTED: sele ( 824) 2791 427.3 1.3e-118
NP_001180418 (OMIM: 615756) selenocysteine inserti (1101) 1036 166.3 6.2e-40
NP_055516 (OMIM: 615756) selenocysteine insertion (1056) 1030 165.4 1.1e-39
>>NP_001269618 (OMIM: 607693,609698) selenocysteine inse (781 aa)
initn: 5131 init1: 5131 opt: 5131 Z-score: 4131.4 bits: 775.2 E(85289): 0
Smith-Waterman score: 5131; 100.0% identity (100.0% similar) in 781 aa overlap (1-781:1-781)
10 20 30 40 50 60
pF1KB8 MVRVLRSMCLPQLCSHILSVCSGTTSDRNVYSVPGSQYLYNQPSCYRGFQTVKHRNENTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVRVLRSMCLPQLCSHILSVCSGTTSDRNVYSVPGSQYLYNQPSCYRGFQTVKHRNENTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PLPQEMKALFKKKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHHLSIYAENSLKSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLPQEMKALFKKKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHHLSIYAENSLKSDG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 YHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSVSTDIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSVSTDIS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTLSTELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTLSTELS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 AAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 QNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQQP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 QDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKECASGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKECASGE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 RGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQENAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQENAVS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 PAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGTELQRDTEASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGTELQRDTEASH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 LAPNHTTFPKIHSRRFRDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKTKRRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAPNHTTFPKIHSRRFRDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKTKRRL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 VLGLREVLKHLKLKKLKCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFVFALNRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLGLREVLKHLKLKKLKCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFVFALNRKA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 LGRSLNKAVPVSVVGIFSYDGAQDQFHKMVELTVAARQAYKTMLENVQQELVGEPRPQAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGRSLNKAVPVSVVGIFSYDGAQDQFHKMVELTVAARQAYKTMLENVQQELVGEPRPQAP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 PSLPTQGPSCPAEDGPPALKEKEEPHYIEIWKKHLEAYSGCTLELEESLEASTSQMMNLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSLPTQGPSCPAEDGPPALKEKEEPHYIEIWKKHLEAYSGCTLELEESLEASTSQMMNLN
730 740 750 760 770 780
pF1KB8 L
:
NP_001 L
>>XP_006717345 (OMIM: 607693,609698) PREDICTED: selenocy (781 aa)
initn: 5131 init1: 5131 opt: 5131 Z-score: 4131.4 bits: 775.2 E(85289): 0
Smith-Waterman score: 5131; 100.0% identity (100.0% similar) in 781 aa overlap (1-781:1-781)
10 20 30 40 50 60
pF1KB8 MVRVLRSMCLPQLCSHILSVCSGTTSDRNVYSVPGSQYLYNQPSCYRGFQTVKHRNENTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MVRVLRSMCLPQLCSHILSVCSGTTSDRNVYSVPGSQYLYNQPSCYRGFQTVKHRNENTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PLPQEMKALFKKKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHHLSIYAENSLKSDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLPQEMKALFKKKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHHLSIYAENSLKSDG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 YHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSVSTDIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSVSTDIS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTLSTELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTLSTELS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 AAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 QNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQQP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 QDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKECASGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKECASGE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 RGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQENAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQENAVS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 PAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGTELQRDTEASH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGTELQRDTEASH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 LAPNHTTFPKIHSRRFRDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKTKRRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LAPNHTTFPKIHSRRFRDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKTKRRL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 VLGLREVLKHLKLKKLKCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFVFALNRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLGLREVLKHLKLKKLKCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFVFALNRKA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 LGRSLNKAVPVSVVGIFSYDGAQDQFHKMVELTVAARQAYKTMLENVQQELVGEPRPQAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGRSLNKAVPVSVVGIFSYDGAQDQFHKMVELTVAARQAYKTMLENVQQELVGEPRPQAP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 PSLPTQGPSCPAEDGPPALKEKEEPHYIEIWKKHLEAYSGCTLELEESLEASTSQMMNLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSLPTQGPSCPAEDGPPALKEKEEPHYIEIWKKHLEAYSGCTLELEESLEASTSQMMNLN
730 740 750 760 770 780
pF1KB8 L
:
XP_006 L
>>NP_001269619 (OMIM: 607693,609698) selenocysteine inse (786 aa)
initn: 4944 init1: 4944 opt: 4944 Z-score: 3981.1 bits: 747.4 E(85289): 5.2e-215
Smith-Waterman score: 4944; 99.7% identity (99.9% similar) in 756 aa overlap (26-781:31-786)
10 20 30 40 50
pF1KB8 MVRVLRSMCLPQLCSHILSVCSGTTSDRNVYSVPGSQYLYNQPSCYRGFQTVKHR
: .:::::::::::::::::::::::::::
NP_001 MAFGASTFPPQYLSSEITLHPYAYSPYTLDSTQNVYSVPGSQYLYNQPSCYRGFQTVKHR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 NENTCPLPQEMKALFKKKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHHLSIYAENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NENTCPLPQEMKALFKKKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHHLSIYAENS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 LKSDGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKSDGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 STDISLLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STDISLLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 STELSAAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STELSAAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQ
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 GSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQ
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 SKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB8 CASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQ
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB8 ENAVSPAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGTELQRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENAVSPAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGTELQRD
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB8 TEASHLAPNHTTFPKIHSRRFRDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEASHLAPNHTTFPKIHSRRFRDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAK
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB8 TKRRLVLGLREVLKHLKLKKLKCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFVFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKRRLVLGLREVLKHLKLKKLKCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFVFA
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB8 LNRKALGRSLNKAVPVSVVGIFSYDGAQDQFHKMVELTVAARQAYKTMLENVQQELVGEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNRKALGRSLNKAVPVSVVGIFSYDGAQDQFHKMVELTVAARQAYKTMLENVQQELVGEP
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB8 RPQAPPSLPTQGPSCPAEDGPPALKEKEEPHYIEIWKKHLEAYSGCTLELEESLEASTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPQAPPSLPTQGPSCPAEDGPPALKEKEEPHYIEIWKKHLEAYSGCTLELEESLEASTSQ
730 740 750 760 770 780
780
pF1KB8 MMNLNL
::::::
NP_001 MMNLNL
>>XP_011517302 (OMIM: 607693,609698) PREDICTED: selenocy (786 aa)
initn: 4944 init1: 4944 opt: 4944 Z-score: 3981.1 bits: 747.4 E(85289): 5.2e-215
Smith-Waterman score: 4944; 99.7% identity (99.9% similar) in 756 aa overlap (26-781:31-786)
10 20 30 40 50
pF1KB8 MVRVLRSMCLPQLCSHILSVCSGTTSDRNVYSVPGSQYLYNQPSCYRGFQTVKHR
: .:::::::::::::::::::::::::::
XP_011 MAFGASTFPPQYLSSEITLHPYAYSPYTLDSTQNVYSVPGSQYLYNQPSCYRGFQTVKHR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 NENTCPLPQEMKALFKKKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHHLSIYAENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NENTCPLPQEMKALFKKKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHHLSIYAENS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 LKSDGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKSDGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 STDISLLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STDISLLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTL
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 STELSAAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STELSAAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQ
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 GSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQ
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 SKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB8 CASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQ
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB8 ENAVSPAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGTELQRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENAVSPAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGTELQRD
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB8 TEASHLAPNHTTFPKIHSRRFRDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEASHLAPNHTTFPKIHSRRFRDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAK
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB8 TKRRLVLGLREVLKHLKLKKLKCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFVFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKRRLVLGLREVLKHLKLKKLKCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFVFA
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB8 LNRKALGRSLNKAVPVSVVGIFSYDGAQDQFHKMVELTVAARQAYKTMLENVQQELVGEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNRKALGRSLNKAVPVSVVGIFSYDGAQDQFHKMVELTVAARQAYKTMLENVQQELVGEP
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB8 RPQAPPSLPTQGPSCPAEDGPPALKEKEEPHYIEIWKKHLEAYSGCTLELEESLEASTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPQAPPSLPTQGPSCPAEDGPPALKEKEEPHYIEIWKKHLEAYSGCTLELEESLEASTSQ
730 740 750 760 770 780
780
pF1KB8 MMNLNL
::::::
XP_011 MMNLNL
>>NP_076982 (OMIM: 607693,609698) selenocysteine inserti (854 aa)
initn: 4944 init1: 4944 opt: 4944 Z-score: 3980.5 bits: 747.5 E(85289): 5.6e-215
Smith-Waterman score: 4944; 99.7% identity (99.9% similar) in 756 aa overlap (26-781:99-854)
10 20 30 40 50
pF1KB8 MVRVLRSMCLPQLCSHILSVCSGTTSDRNVYSVPGSQYLYNQPSCYRGFQTVKHR
: .:::::::::::::::::::::::::::
NP_076 MAFGASTFPPQYLSSEITLHPYAYSPYTLDSTQNVYSVPGSQYLYNQPSCYRGFQTVKHR
70 80 90 100 110 120
60 70 80 90 100 110
pF1KB8 NENTCPLPQEMKALFKKKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHHLSIYAENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 NENTCPLPQEMKALFKKKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHHLSIYAENS
130 140 150 160 170 180
120 130 140 150 160 170
pF1KB8 LKSDGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 LKSDGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSV
190 200 210 220 230 240
180 190 200 210 220 230
pF1KB8 STDISLLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 STDISLLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTL
250 260 270 280 290 300
240 250 260 270 280 290
pF1KB8 STELSAAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 STELSAAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQ
310 320 330 340 350 360
300 310 320 330 340 350
pF1KB8 GSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 GSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQ
370 380 390 400 410 420
360 370 380 390 400 410
pF1KB8 SKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 SKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKE
430 440 450 460 470 480
420 430 440 450 460 470
pF1KB8 CASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 CASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQ
490 500 510 520 530 540
480 490 500 510 520 530
pF1KB8 ENAVSPAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGTELQRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 ENAVSPAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGTELQRD
550 560 570 580 590 600
540 550 560 570 580 590
pF1KB8 TEASHLAPNHTTFPKIHSRRFRDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 TEASHLAPNHTTFPKIHSRRFRDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAK
610 620 630 640 650 660
600 610 620 630 640 650
pF1KB8 TKRRLVLGLREVLKHLKLKKLKCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFVFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 TKRRLVLGLREVLKHLKLKKLKCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFVFA
670 680 690 700 710 720
660 670 680 690 700 710
pF1KB8 LNRKALGRSLNKAVPVSVVGIFSYDGAQDQFHKMVELTVAARQAYKTMLENVQQELVGEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 LNRKALGRSLNKAVPVSVVGIFSYDGAQDQFHKMVELTVAARQAYKTMLENVQQELVGEP
730 740 750 760 770 780
720 730 740 750 760 770
pF1KB8 RPQAPPSLPTQGPSCPAEDGPPALKEKEEPHYIEIWKKHLEAYSGCTLELEESLEASTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 RPQAPPSLPTQGPSCPAEDGPPALKEKEEPHYIEIWKKHLEAYSGCTLELEESLEASTSQ
790 800 810 820 830 840
780
pF1KB8 MMNLNL
::::::
NP_076 MMNLNL
850
>>NP_001269617 (OMIM: 607693,609698) selenocysteine inse (853 aa)
initn: 4632 init1: 4632 opt: 4926 Z-score: 3966.1 bits: 744.8 E(85289): 3.6e-214
Smith-Waterman score: 4926; 99.6% identity (99.7% similar) in 756 aa overlap (26-781:99-853)
10 20 30 40 50
pF1KB8 MVRVLRSMCLPQLCSHILSVCSGTTSDRNVYSVPGSQYLYNQPSCYRGFQTVKHR
: .:::::::::::::::::::::::::::
NP_001 MAFGASTFPPQYLSSEITLHPYAYSPYTLDSTQNVYSVPGSQYLYNQPSCYRGFQTVKHR
70 80 90 100 110 120
60 70 80 90 100 110
pF1KB8 NENTCPLPQEMKALFKKKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHHLSIYAENS
::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
NP_001 NENTCPLPQEMKALFKK-TYDEKKTYDQQKFDSERADGTISSEIKSARGSHHLSIYAENS
130 140 150 160 170 180
120 130 140 150 160 170
pF1KB8 LKSDGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKSDGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSV
190 200 210 220 230 240
180 190 200 210 220 230
pF1KB8 STDISLLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STDISLLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTL
250 260 270 280 290 300
240 250 260 270 280 290
pF1KB8 STELSAAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STELSAAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQ
310 320 330 340 350 360
300 310 320 330 340 350
pF1KB8 GSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQ
370 380 390 400 410 420
360 370 380 390 400 410
pF1KB8 SKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKE
430 440 450 460 470 480
420 430 440 450 460 470
pF1KB8 CASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQ
490 500 510 520 530 540
480 490 500 510 520 530
pF1KB8 ENAVSPAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGTELQRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENAVSPAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGTELQRD
550 560 570 580 590 600
540 550 560 570 580 590
pF1KB8 TEASHLAPNHTTFPKIHSRRFRDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEASHLAPNHTTFPKIHSRRFRDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAK
610 620 630 640 650 660
600 610 620 630 640 650
pF1KB8 TKRRLVLGLREVLKHLKLKKLKCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFVFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TKRRLVLGLREVLKHLKLKKLKCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFVFA
670 680 690 700 710 720
660 670 680 690 700 710
pF1KB8 LNRKALGRSLNKAVPVSVVGIFSYDGAQDQFHKMVELTVAARQAYKTMLENVQQELVGEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNRKALGRSLNKAVPVSVVGIFSYDGAQDQFHKMVELTVAARQAYKTMLENVQQELVGEP
730 740 750 760 770 780
720 730 740 750 760 770
pF1KB8 RPQAPPSLPTQGPSCPAEDGPPALKEKEEPHYIEIWKKHLEAYSGCTLELEESLEASTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPQAPPSLPTQGPSCPAEDGPPALKEKEEPHYIEIWKKHLEAYSGCTLELEESLEASTSQ
790 800 810 820 830 840
780
pF1KB8 MMNLNL
::::::
NP_001 MMNLNL
850
>>XP_005252259 (OMIM: 607693,609698) PREDICTED: selenocy (555 aa)
initn: 3630 init1: 3630 opt: 3630 Z-score: 2927.2 bits: 551.9 E(85289): 2.6e-156
Smith-Waterman score: 3630; 100.0% identity (100.0% similar) in 555 aa overlap (227-781:1-555)
200 210 220 230 240 250
pF1KB8 IVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTLSTELSAAPKNVTSMINLKTIA
::::::::::::::::::::::::::::::
XP_005 MGYVVRQTLSTELSAAPKNVTSMINLKTIA
10 20 30
260 270 280 290 300 310
pF1KB8 SSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEASRKNKKKKEKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEASRKNKKKKEKST
40 50 60 70 80 90
320 330 340 350 360 370
pF1KB8 SKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQQPQDNFKNNVKKSQLPVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQQPQDNFKNNVKKSQLPVQ
100 110 120 130 140 150
380 390 400 410 420 430
pF1KB8 LDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKECASGERGRRMSQMKTPHNPLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKECASGERGRRMSQMKTPHNPLD
160 170 180 190 200 210
440 450 460 470 480 490
pF1KB8 SSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQENAVSPAFTSDDTQDGESGGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQENAVSPAFTSDDTQDGESGGD
220 230 240 250 260 270
500 510 520 530 540 550
pF1KB8 DQFPEQAELSGPEGMDELISTPSVEDKSEEPPGTELQRDTEASHLAPNHTTFPKIHSRRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DQFPEQAELSGPEGMDELISTPSVEDKSEEPPGTELQRDTEASHLAPNHTTFPKIHSRRF
280 290 300 310 320 330
560 570 580 590 600 610
pF1KB8 RDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLKKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLKKL
340 350 360 370 380 390
620 630 640 650 660 670
pF1KB8 KCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFVFALNRKALGRSLNKAVPVSVVGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFVFALNRKALGRSLNKAVPVSVVGI
400 410 420 430 440 450
680 690 700 710 720 730
pF1KB8 FSYDGAQDQFHKMVELTVAARQAYKTMLENVQQELVGEPRPQAPPSLPTQGPSCPAEDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSYDGAQDQFHKMVELTVAARQAYKTMLENVQQELVGEPRPQAPPSLPTQGPSCPAEDGP
460 470 480 490 500 510
740 750 760 770 780
pF1KB8 PALKEKEEPHYIEIWKKHLEAYSGCTLELEESLEASTSQMMNLNL
:::::::::::::::::::::::::::::::::::::::::::::
XP_005 PALKEKEEPHYIEIWKKHLEAYSGCTLELEESLEASTSQMMNLNL
520 530 540 550
>>XP_016870614 (OMIM: 607693,609698) PREDICTED: selenocy (559 aa)
initn: 3591 init1: 3591 opt: 3594 Z-score: 2898.2 bits: 546.6 E(85289): 1.1e-154
Smith-Waterman score: 3594; 98.9% identity (99.5% similar) in 556 aa overlap (226-781:4-559)
200 210 220 230 240 250
pF1KB8 EIVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTLSTELSAAPKNVTSMINLKTI
:. :..::::::::::::::::::::::
XP_016 MPLPILLHVQETLSTELSAAPKNVTSMINLKTI
10 20 30
260 270 280 290 300 310
pF1KB8 ASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEASRKNKKKKEKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQGSDLEQNEASRKNKKKKEKS
40 50 60 70 80 90
320 330 340 350 360 370
pF1KB8 TSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQQPQDNFKNNVKKSQLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQSKQQPQDNFKNNVKKSQLPV
100 110 120 130 140 150
380 390 400 410 420 430
pF1KB8 QLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKECASGERGRRMSQMKTPHNPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKECASGERGRRMSQMKTPHNPL
160 170 180 190 200 210
440 450 460 470 480 490
pF1KB8 DSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQENAVSPAFTSDDTQDGESGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQENAVSPAFTSDDTQDGESGG
220 230 240 250 260 270
500 510 520 530 540 550
pF1KB8 DDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGTELQRDTEASHLAPNHTTFPKIHSRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGTELQRDTEASHLAPNHTTFPKIHSRR
280 290 300 310 320 330
560 570 580 590 600 610
pF1KB8 FRDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAKTKRRLVLGLREVLKHLKLKK
340 350 360 370 380 390
620 630 640 650 660 670
pF1KB8 LKCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFVFALNRKALGRSLNKAVPVSVVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFVFALNRKALGRSLNKAVPVSVVG
400 410 420 430 440 450
680 690 700 710 720 730
pF1KB8 IFSYDGAQDQFHKMVELTVAARQAYKTMLENVQQELVGEPRPQAPPSLPTQGPSCPAEDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IFSYDGAQDQFHKMVELTVAARQAYKTMLENVQQELVGEPRPQAPPSLPTQGPSCPAEDG
460 470 480 490 500 510
740 750 760 770 780
pF1KB8 PPALKEKEEPHYIEIWKKHLEAYSGCTLELEESLEASTSQMMNLNL
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPALKEKEEPHYIEIWKKHLEAYSGCTLELEESLEASTSQMMNLNL
520 530 540 550
>>XP_011517305 (OMIM: 607693,609698) PREDICTED: selenocy (747 aa)
initn: 3446 init1: 3446 opt: 3446 Z-score: 2777.4 bits: 524.6 E(85289): 5.8e-148
Smith-Waterman score: 4619; 94.6% identity (94.7% similar) in 756 aa overlap (26-781:31-747)
10 20 30 40 50
pF1KB8 MVRVLRSMCLPQLCSHILSVCSGTTSDRNVYSVPGSQYLYNQPSCYRGFQTVKHR
: .:::::::::::::::::::::::::::
XP_011 MAFGASTFPPQYLSSEITLHPYAYSPYTLDSTQNVYSVPGSQYLYNQPSCYRGFQTVKHR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 NENTCPLPQEMKALFKKKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHHLSIYAENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NENTCPLPQEMKALFKKKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHHLSIYAENS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 LKSDGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKSDGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 STDISLLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTL
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 STDISLLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTR---------------
190 200 210 220
240 250 260 270 280 290
pF1KB8 STELSAAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQ
::::::::::::::::::::::::::::::::::::
XP_011 ------------------------DPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQ
230 240 250 260
300 310 320 330 340 350
pF1KB8 GSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQ
270 280 290 300 310 320
360 370 380 390 400 410
pF1KB8 SKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKE
330 340 350 360 370 380
420 430 440 450 460 470
pF1KB8 CASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQ
390 400 410 420 430 440
480 490 500 510 520 530
pF1KB8 ENAVSPAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGTELQRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENAVSPAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGTELQRD
450 460 470 480 490 500
540 550 560 570 580 590
pF1KB8 TEASHLAPNHTTFPKIHSRRFRDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEASHLAPNHTTFPKIHSRRFRDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAK
510 520 530 540 550 560
600 610 620 630 640 650
pF1KB8 TKRRLVLGLREVLKHLKLKKLKCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFVFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKRRLVLGLREVLKHLKLKKLKCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFVFA
570 580 590 600 610 620
660 670 680 690 700 710
pF1KB8 LNRKALGRSLNKAVPVSVVGIFSYDGAQDQFHKMVELTVAARQAYKTMLENVQQELVGEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNRKALGRSLNKAVPVSVVGIFSYDGAQDQFHKMVELTVAARQAYKTMLENVQQELVGEP
630 640 650 660 670 680
720 730 740 750 760 770
pF1KB8 RPQAPPSLPTQGPSCPAEDGPPALKEKEEPHYIEIWKKHLEAYSGCTLELEESLEASTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPQAPPSLPTQGPSCPAEDGPPALKEKEEPHYIEIWKKHLEAYSGCTLELEESLEASTSQ
690 700 710 720 730 740
780
pF1KB8 MMNLNL
::::::
XP_011 MMNLNL
>>XP_005252253 (OMIM: 607693,609698) PREDICTED: selenocy (815 aa)
initn: 3446 init1: 3446 opt: 3446 Z-score: 2776.8 bits: 524.7 E(85289): 6.2e-148
Smith-Waterman score: 4619; 94.6% identity (94.7% similar) in 756 aa overlap (26-781:99-815)
10 20 30 40 50
pF1KB8 MVRVLRSMCLPQLCSHILSVCSGTTSDRNVYSVPGSQYLYNQPSCYRGFQTVKHR
: .:::::::::::::::::::::::::::
XP_005 MAFGASTFPPQYLSSEITLHPYAYSPYTLDSTQNVYSVPGSQYLYNQPSCYRGFQTVKHR
70 80 90 100 110 120
60 70 80 90 100 110
pF1KB8 NENTCPLPQEMKALFKKKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHHLSIYAENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NENTCPLPQEMKALFKKKTYDEKKTYDQQKFDSERADGTISSEIKSARGSHHLSIYAENS
130 140 150 160 170 180
120 130 140 150 160 170
pF1KB8 LKSDGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKSDGYHKRTDRKSRIIAKNVSTSKPEFEFTTLDFPELQGAENNMSEIQKQPKWGPVHSV
190 200 210 220 230 240
180 190 200 210 220 230
pF1KB8 STDISLLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTRELSWTPMGYVVRQTL
:::::::::::::::::::::::::::::::::::::::::::::
XP_005 STDISLLREVVKPAAVLSKGEIVVKNNPNESVTANAATNSPSCTR---------------
250 260 270 280 290
240 250 260 270 280 290
pF1KB8 STELSAAPKNVTSMINLKTIASSADPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQ
::::::::::::::::::::::::::::::::::::
XP_005 ------------------------DPKNVSIPSSEALSSDPSYNKEKHIIHPTQKSKASQ
300 310 320
300 310 320 330 340 350
pF1KB8 GSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSDLEQNEASRKNKKKKEKSTSKYEVLTVQEPPRIEDAEEFPNLAVASERRDRIETPKFQ
330 340 350 360 370 380
360 370 380 390 400 410
pF1KB8 SKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKQQPQDNFKNNVKKSQLPVQLDLGGMLTALEKKQHSQHAKQSSKPVVVSVGAVPVLSKE
390 400 410 420 430 440
420 430 440 450 460 470
pF1KB8 CASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CASGERGRRMSQMKTPHNPLDSSAPLMKKGKQREIPKAKKPTSLKKIILKERQERKQRLQ
450 460 470 480 490 500
480 490 500 510 520 530
pF1KB8 ENAVSPAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGTELQRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENAVSPAFTSDDTQDGESGGDDQFPEQAELSGPEGMDELISTPSVEDKSEEPPGTELQRD
510 520 530 540 550 560
540 550 560 570 580 590
pF1KB8 TEASHLAPNHTTFPKIHSRRFRDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TEASHLAPNHTTFPKIHSRRFRDYCSQMLSKEVDACVTDLLKELVRFQDRMYQKDPVKAK
570 580 590 600 610 620
600 610 620 630 640 650
pF1KB8 TKRRLVLGLREVLKHLKLKKLKCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFVFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TKRRLVLGLREVLKHLKLKKLKCVIISPNCEKIQSKGGLDDTLHTIIDYACEQNIPFVFA
630 640 650 660 670 680
660 670 680 690 700 710
pF1KB8 LNRKALGRSLNKAVPVSVVGIFSYDGAQDQFHKMVELTVAARQAYKTMLENVQQELVGEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNRKALGRSLNKAVPVSVVGIFSYDGAQDQFHKMVELTVAARQAYKTMLENVQQELVGEP
690 700 710 720 730 740
720 730 740 750 760 770
pF1KB8 RPQAPPSLPTQGPSCPAEDGPPALKEKEEPHYIEIWKKHLEAYSGCTLELEESLEASTSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RPQAPPSLPTQGPSCPAEDGPPALKEKEEPHYIEIWKKHLEAYSGCTLELEESLEASTSQ
750 760 770 780 790 800
780
pF1KB8 MMNLNL
::::::
XP_005 MMNLNL
810
781 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 13:18:01 2016 done: Fri Nov 4 13:18:03 2016
Total Scan time: 11.810 Total Display time: 0.210
Function used was FASTA [36.3.4 Apr, 2011]