FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8603, 412 aa 1>>>pF1KB8603 412 - 412 aa - 412 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3951+/-0.000856; mu= 16.4495+/- 0.051 mean_var=63.8414+/-12.556, 0's: 0 Z-trim(105.8): 20 B-trim: 0 in 0/50 Lambda= 0.160518 statistics sampled from 8638 (8646) to 8638 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.648), E-opt: 0.2 (0.266), width: 16 Scan time: 2.640 The best scores are: opt bits E(32554) CCDS53313.1 EIF2B3 gene_id:8891|Hs108|chr1 ( 412) 2713 637.1 9.3e-183 CCDS72775.1 EIF2B3 gene_id:8891|Hs108|chr1 ( 401) 2631 618.1 4.7e-177 CCDS517.1 EIF2B3 gene_id:8891|Hs108|chr1 ( 452) 2631 618.1 5.2e-177 >>CCDS53313.1 EIF2B3 gene_id:8891|Hs108|chr1 (412 aa) initn: 2713 init1: 2713 opt: 2713 Z-score: 3394.6 bits: 637.1 E(32554): 9.3e-183 Smith-Waterman score: 2713; 100.0% identity (100.0% similar) in 412 aa overlap (1-412:1-412) 10 20 30 40 50 60 pF1KB8 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 FRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 FRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEEL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 VIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 SSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 YVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 YVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGP 310 320 330 340 350 360 370 380 390 400 410 pF1KB8 ETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGYVSPCTHLRQR :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGYVSPCTHLRQR 370 380 390 400 410 >>CCDS72775.1 EIF2B3 gene_id:8891|Hs108|chr1 (401 aa) initn: 2631 init1: 2631 opt: 2631 Z-score: 3292.1 bits: 618.1 E(32554): 4.7e-177 Smith-Waterman score: 2631; 100.0% identity (100.0% similar) in 401 aa overlap (1-401:1-401) 10 20 30 40 50 60 pF1KB8 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 FRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 FRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEEL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 VIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 SSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 YVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 YVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGP 310 320 330 340 350 360 370 380 390 400 410 pF1KB8 ETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGYVSPCTHLRQR ::::::::::::::::::::::::::::::::::::::::: CCDS72 ETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEG 370 380 390 400 >>CCDS517.1 EIF2B3 gene_id:8891|Hs108|chr1 (452 aa) initn: 2631 init1: 2631 opt: 2631 Z-score: 3291.3 bits: 618.1 E(32554): 5.2e-177 Smith-Waterman score: 2631; 100.0% identity (100.0% similar) in 401 aa overlap (1-401:1-401) 10 20 30 40 50 60 pF1KB8 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 MEFQAVVMAVGGGSRMTDLTSSIPKPLLPVGNKPLIWYPLNLLERVGFEEVIVVTTRDVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 KALCAEFKMKMKPDIVCIPDDADMGTADSLRYIYPKLKTDVLVLSCDLITDVALHEVVDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 FRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 FRAYDASLAMLMRKGQDSIEPVPGQKGKKKAVEQRDFIGVDSTGKRLLFMANEADLDEEL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 VIKGSILQKHPRIRFHTGLVDAHLYCLKKYIVDFLMENGSITSIRSELIPYLVRKQFSSA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 SSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 SSQQGQEEKEEDLKKKELKSLDIYSFIKEANTLNLAPYDACWNACRGDRWEDLSRSQVRC 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 YVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS51 YVHIMKEGLCSRVSTLGLYMEANRQVPKLLSALCPEEPPVHSSAQIVSKHLVGVDSLIGP 310 320 330 340 350 360 370 380 390 400 410 pF1KB8 ETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGYVSPCTHLRQR ::::::::::::::::::::::::::::::::::::::::: CCDS51 ETQIGEKSSIKRSVIGSSCLIKDRVTITNCLLMNSVTVEEGSNIQGSVICNNAVIEKGAD 370 380 390 400 410 420 CCDS51 IKDCLIGSGQRIEAKAKRVNEVIVGNDQLMEI 430 440 450 412 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 13:40:09 2016 done: Fri Nov 4 13:40:10 2016 Total Scan time: 2.640 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]