FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8604, 413 aa 1>>>pF1KB8604 413 - 413 aa - 413 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.1436+/-0.000317; mu= 5.5801+/- 0.020 mean_var=188.2596+/-37.428, 0's: 0 Z-trim(122.5): 45 B-trim: 7 in 2/57 Lambda= 0.093475 statistics sampled from 40750 (40803) to 40750 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.797), E-opt: 0.2 (0.478), width: 16 Scan time: 9.120 The best scores are: opt bits E(85289) XP_011526165 (OMIM: 604840) PREDICTED: peptidyl-pr ( 413) 2726 379.5 8.2e-105 NP_036313 (OMIM: 604840) peptidyl-prolyl cis-trans ( 413) 2726 379.5 8.2e-105 NP_001295302 (OMIM: 604840) peptidyl-prolyl cis-tr ( 412) 2709 377.2 4e-104 XP_011526166 (OMIM: 604840) PREDICTED: peptidyl-pr ( 383) 2249 315.2 1.8e-85 XP_011519231 (OMIM: 600611) PREDICTED: peptidyl-pr ( 414) 313 54.1 7.5e-07 NP_002005 (OMIM: 600611) peptidyl-prolyl cis-trans ( 459) 313 54.2 8.1e-07 NP_004108 (OMIM: 602623,608516) peptidyl-prolyl ci ( 457) 273 48.8 3.4e-05 NP_001139247 (OMIM: 602623,608516) peptidyl-prolyl ( 457) 273 48.8 3.4e-05 NP_001139248 (OMIM: 602623,608516) peptidyl-prolyl ( 457) 273 48.8 3.4e-05 NP_005029 (OMIM: 601753) peptidyl-prolyl cis-trans ( 370) 265 47.6 6.1e-05 XP_016868230 (OMIM: 604839) PREDICTED: inactive pe ( 317) 233 43.2 0.0011 NP_001128683 (OMIM: 604839) inactive peptidyl-prol ( 322) 228 42.6 0.0017 NP_003593 (OMIM: 604839) inactive peptidyl-prolyl ( 327) 228 42.6 0.0018 NP_001268233 (OMIM: 604839) inactive peptidyl-prol ( 297) 209 40.0 0.0096 >>XP_011526165 (OMIM: 604840) PREDICTED: peptidyl-prolyl (413 aa) initn: 2726 init1: 2726 opt: 2726 Z-score: 2002.7 bits: 379.5 E(85289): 8.2e-105 Smith-Waterman score: 2726; 100.0% identity (100.0% similar) in 413 aa overlap (1-413:1-413) 10 20 30 40 50 60 pF1KB8 MASCAEPSEPSAPLPAGVPPLEDFEVLDGVEDAEGEEEEEEEEEEEDDLSELPPLEDMGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MASCAEPSEPSAPLPAGVPPLEDFEVLDGVEDAEGEEEEEEEEEEEDDLSELPPLEDMGQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PPAEEAEQPGALAREFLAAMEPEPAPAPAPEEWLDILGNGLLRKKTLVPGPPGSSRPVKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPAEEAEQPGALAREFLAAMEPEPAPAPAPEEWLDILGNGLLRKKTLVPGPPGSSRPVKG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QVVTVHLQTSLENGTRVQEEPELVFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVVTVHLQTSLENGTRVQEEPELVFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PQGSRSPYIPPHAALCLEVTLKTAVDGPDLEMLTGQERVALANRKRECGNAHYQRADFVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQGSRSPYIPPHAALCLEVTLKTAVDGPDLEMLTGQERVALANRKRECGNAHYQRADFVL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 AANSYDLAIKAITSSAKVDMTFEEEAQLLQLKVKCLNNLAASQLKLDHYRAALRSCSLVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AANSYDLAIKAITSSAKVDMTFEEEAQLLQLKVKCLNNLAASQLKLDHYRAALRSCSLVL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 EHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKHAAQRST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKHAAQRST 310 320 330 340 350 360 370 380 390 400 410 pF1KB8 ETALYRKMLGNPSRLPAKCPGKGAWSIPWKWLFGATAVALGGVALSVVIAARN ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ETALYRKMLGNPSRLPAKCPGKGAWSIPWKWLFGATAVALGGVALSVVIAARN 370 380 390 400 410 >>NP_036313 (OMIM: 604840) peptidyl-prolyl cis-trans iso (413 aa) initn: 2726 init1: 2726 opt: 2726 Z-score: 2002.7 bits: 379.5 E(85289): 8.2e-105 Smith-Waterman score: 2726; 100.0% identity (100.0% similar) in 413 aa overlap (1-413:1-413) 10 20 30 40 50 60 pF1KB8 MASCAEPSEPSAPLPAGVPPLEDFEVLDGVEDAEGEEEEEEEEEEEDDLSELPPLEDMGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 MASCAEPSEPSAPLPAGVPPLEDFEVLDGVEDAEGEEEEEEEEEEEDDLSELPPLEDMGQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PPAEEAEQPGALAREFLAAMEPEPAPAPAPEEWLDILGNGLLRKKTLVPGPPGSSRPVKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 PPAEEAEQPGALAREFLAAMEPEPAPAPAPEEWLDILGNGLLRKKTLVPGPPGSSRPVKG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QVVTVHLQTSLENGTRVQEEPELVFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 QVVTVHLQTSLENGTRVQEEPELVFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PQGSRSPYIPPHAALCLEVTLKTAVDGPDLEMLTGQERVALANRKRECGNAHYQRADFVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 PQGSRSPYIPPHAALCLEVTLKTAVDGPDLEMLTGQERVALANRKRECGNAHYQRADFVL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 AANSYDLAIKAITSSAKVDMTFEEEAQLLQLKVKCLNNLAASQLKLDHYRAALRSCSLVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 AANSYDLAIKAITSSAKVDMTFEEEAQLLQLKVKCLNNLAASQLKLDHYRAALRSCSLVL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 EHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKHAAQRST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 EHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKHAAQRST 310 320 330 340 350 360 370 380 390 400 410 pF1KB8 ETALYRKMLGNPSRLPAKCPGKGAWSIPWKWLFGATAVALGGVALSVVIAARN ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_036 ETALYRKMLGNPSRLPAKCPGKGAWSIPWKWLFGATAVALGGVALSVVIAARN 370 380 390 400 410 >>NP_001295302 (OMIM: 604840) peptidyl-prolyl cis-trans (412 aa) initn: 1484 init1: 1484 opt: 2709 Z-score: 1990.3 bits: 377.2 E(85289): 4e-104 Smith-Waterman score: 2709; 99.8% identity (99.8% similar) in 413 aa overlap (1-413:1-412) 10 20 30 40 50 60 pF1KB8 MASCAEPSEPSAPLPAGVPPLEDFEVLDGVEDAEGEEEEEEEEEEEDDLSELPPLEDMGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MASCAEPSEPSAPLPAGVPPLEDFEVLDGVEDAEGEEEEEEEEEEEDDLSELPPLEDMGQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PPAEEAEQPGALAREFLAAMEPEPAPAPAPEEWLDILGNGLLRKKTLVPGPPGSSRPVKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPAEEAEQPGALAREFLAAMEPEPAPAPAPEEWLDILGNGLLRKKTLVPGPPGSSRPVKG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QVVTVHLQTSLENGTRVQEEPELVFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QVVTVHLQTSLENGTRVQEEPELVFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PQGSRSPYIPPHAALCLEVTLKTAVDGPDLEMLTGQERVALANRKRECGNAHYQRADFVL ::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PQG-RSPYIPPHAALCLEVTLKTAVDGPDLEMLTGQERVALANRKRECGNAHYQRADFVL 190 200 210 220 230 250 260 270 280 290 300 pF1KB8 AANSYDLAIKAITSSAKVDMTFEEEAQLLQLKVKCLNNLAASQLKLDHYRAALRSCSLVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AANSYDLAIKAITSSAKVDMTFEEEAQLLQLKVKCLNNLAASQLKLDHYRAALRSCSLVL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB8 EHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKHAAQRST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKHAAQRST 300 310 320 330 340 350 370 380 390 400 410 pF1KB8 ETALYRKMLGNPSRLPAKCPGKGAWSIPWKWLFGATAVALGGVALSVVIAARN ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETALYRKMLGNPSRLPAKCPGKGAWSIPWKWLFGATAVALGGVALSVVIAARN 360 370 380 390 400 410 >>XP_011526166 (OMIM: 604840) PREDICTED: peptidyl-prolyl (383 aa) initn: 2249 init1: 2249 opt: 2249 Z-score: 1655.5 bits: 315.2 E(85289): 1.8e-85 Smith-Waterman score: 2249; 100.0% identity (100.0% similar) in 341 aa overlap (1-341:1-341) 10 20 30 40 50 60 pF1KB8 MASCAEPSEPSAPLPAGVPPLEDFEVLDGVEDAEGEEEEEEEEEEEDDLSELPPLEDMGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MASCAEPSEPSAPLPAGVPPLEDFEVLDGVEDAEGEEEEEEEEEEEDDLSELPPLEDMGQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PPAEEAEQPGALAREFLAAMEPEPAPAPAPEEWLDILGNGLLRKKTLVPGPPGSSRPVKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPAEEAEQPGALAREFLAAMEPEPAPAPAPEEWLDILGNGLLRKKTLVPGPPGSSRPVKG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 QVVTVHLQTSLENGTRVQEEPELVFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVVTVHLQTSLENGTRVQEEPELVFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PQGSRSPYIPPHAALCLEVTLKTAVDGPDLEMLTGQERVALANRKRECGNAHYQRADFVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PQGSRSPYIPPHAALCLEVTLKTAVDGPDLEMLTGQERVALANRKRECGNAHYQRADFVL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 AANSYDLAIKAITSSAKVDMTFEEEAQLLQLKVKCLNNLAASQLKLDHYRAALRSCSLVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AANSYDLAIKAITSSAKVDMTFEEEAQLLQLKVKCLNNLAASQLKLDHYRAALRSCSLVL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 EHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKHAAQRST ::::::::::::::::::::::::::::::::::::::::: XP_011 EHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKLPLPSADDPRRALKAGEEA 310 320 330 340 350 360 370 380 390 400 410 pF1KB8 ETALYRKMLGNPSRLPAKCPGKGAWSIPWKWLFGATAVALGGVALSVVIAARN XP_011 CGAAEHGDRLVPENAGQPQPAAC 370 380 >>XP_011519231 (OMIM: 600611) PREDICTED: peptidyl-prolyl (414 aa) initn: 367 init1: 165 opt: 313 Z-score: 244.0 bits: 54.1 E(85289): 7.5e-07 Smith-Waterman score: 313; 27.5% identity (60.7% similar) in 262 aa overlap (113-369:115-370) 90 100 110 120 130 140 pF1KB8 EPAPAPAPEEWLDILGNGLLRKKTLVPGPPGSSRPVKGQVVTVHLQTSLENGTRVQEEPE : ..: .: .: : :. .. .. .. : XP_011 FEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD--KLFDQRE 90 100 110 120 130 140 150 160 170 180 190 pF1KB8 LVFTLGD---CDVIQALDLSVPLMDVGETAMVTADSKYCYGPQGSRSPYIPPHAALCLEV : : .:. :. .:. .. :. :: ..: .: .: :... :::.: : :. XP_011 LRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYEL 150 160 170 180 190 200 200 210 220 230 240 250 pF1KB8 TLKTAVDGPDLEMLTGQERVALANRKRECGNAHYQRADFVLAANSYDLAIKAITSSAKVD ::. . . ....:.. .. .: :....... . : .: : :.: . . XP_011 HLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQY----KKIVSWLEYE 210 220 230 240 250 260 270 280 290 300 310 pF1KB8 MTF-EEEAQLLQ-LKVKCLNNLAASQLKLDHYRAALRSCSLVLEHQPDNIKALFRKGKVL .: .:::: : :.. ::: .:::. . ::..::. .:: . .: :.:::.:.. XP_011 SSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAH 260 270 280 290 300 310 320 330 340 350 360 370 pF1KB8 AQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKHAAQRSTETALYRKMLGNPSRLPA ... : .. .:.: :.::. ...:. .. : . : :: .:. XP_011 LAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAEEEN 320 330 340 350 360 370 380 390 400 410 pF1KB8 KCPGKGAWSIPWKWLFGATAVALGGVALSVVIAARN XP_011 KAKAEASSGDHPTDTEMKEEQKSNTAGSQSQVETEA 380 390 400 410 >>NP_002005 (OMIM: 600611) peptidyl-prolyl cis-trans iso (459 aa) initn: 391 init1: 165 opt: 313 Z-score: 243.4 bits: 54.2 E(85289): 8.1e-07 Smith-Waterman score: 313; 27.5% identity (60.7% similar) in 262 aa overlap (113-369:160-415) 90 100 110 120 130 140 pF1KB8 EPAPAPAPEEWLDILGNGLLRKKTLVPGPPGSSRPVKGQVVTVHLQTSLENGTRVQEEPE : ..: .: .: : :. .. .. .. : NP_002 FEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD--KLFDQRE 130 140 150 160 170 180 150 160 170 180 190 pF1KB8 LVFTLGD---CDVIQALDLSVPLMDVGETAMVTADSKYCYGPQGSRSPYIPPHAALCLEV : : .:. :. .:. .. :. :: ..: .: .: :... :::.: : :. NP_002 LRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYEL 190 200 210 220 230 240 200 210 220 230 240 250 pF1KB8 TLKTAVDGPDLEMLTGQERVALANRKRECGNAHYQRADFVLAANSYDLAIKAITSSAKVD ::. . . ....:.. .. .: :....... . : .: : :.: . . NP_002 HLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQY----KKIVSWLEYE 250 260 270 280 290 300 260 270 280 290 300 310 pF1KB8 MTF-EEEAQLLQ-LKVKCLNNLAASQLKLDHYRAALRSCSLVLEHQPDNIKALFRKGKVL .: .:::: : :.. ::: .:::. . ::..::. .:: . .: :.:::.:.. NP_002 SSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAH 310 320 330 340 350 360 320 330 340 350 360 370 pF1KB8 AQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKHAAQRSTETALYRKMLGNPSRLPA ... : .. .:.: :.::. ...:. .. : . : :: .:. NP_002 LAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAEEEN 370 380 390 400 410 420 380 390 400 410 pF1KB8 KCPGKGAWSIPWKWLFGATAVALGGVALSVVIAARN NP_002 KAKAEASSGDHPTDTEMKEEQKSNTAGSQSQVETEA 430 440 450 >>NP_004108 (OMIM: 602623,608516) peptidyl-prolyl cis-tr (457 aa) initn: 218 init1: 133 opt: 273 Z-score: 214.3 bits: 48.8 E(85289): 3.4e-05 Smith-Waterman score: 273; 23.7% identity (55.7% similar) in 287 aa overlap (95-378:141-422) 70 80 90 100 110 120 pF1KB8 EAEQPGALAREFLAAMEPEPAPAPAPEEWLDILGNGLLRKKTLVPGPPGSSRPVKGQVVT :.. .: . ..: : : : : .: .: NP_004 YAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGE-GYSNPNEGATVE 120 130 140 150 160 130 140 150 160 170 180 pF1KB8 VHLQTSLENGTRVQEEPELVFTLG---DCDVIQALDLSVPLMDVGETAMVTADSKYCYGP .::. . : :. . ...::.: : :. ..: .. :. : .. .: .: NP_004 IHLEG--RCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGE 170 180 190 200 210 220 190 200 210 220 230 240 pF1KB8 QGSRSPYIPPHAALCLEVTLKTAVDGPDLEMLTGQERVALANRKRECGNAHYQRADFVLA :. . : :.: : :::::. . . . .:.. : .: :..... . .. : NP_004 AGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQA 230 240 250 260 270 280 250 260 270 280 290 300 pF1KB8 ANSYDLAIKAITSSAKVDMTFEEEAQLLQLKVKCLNNLAASQLKLDHYRAALRSCSLVLE . .: .. . . .. .: .. . . ::: ::: .: :.. :. .: NP_004 VIQYGKIVSWLE--MEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALG 290 300 310 320 330 340 310 320 330 340 350 360 pF1KB8 HQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKHAAQRSTE . : :.:.:.:.. ..:. : .. .:...:.::. . ..: :: . . NP_004 LDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERD 350 360 370 380 390 400 370 380 390 400 410 pF1KB8 TALYRKMLGNPSRLPAKCPGKGAWSIPWKWLFGATAVALGGVALSVVIAARN .: .:. . .. :: NP_004 RRIYANMFKKFAEQDAKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV 410 420 430 440 450 >>NP_001139247 (OMIM: 602623,608516) peptidyl-prolyl cis (457 aa) initn: 218 init1: 133 opt: 273 Z-score: 214.3 bits: 48.8 E(85289): 3.4e-05 Smith-Waterman score: 273; 23.7% identity (55.7% similar) in 287 aa overlap (95-378:141-422) 70 80 90 100 110 120 pF1KB8 EAEQPGALAREFLAAMEPEPAPAPAPEEWLDILGNGLLRKKTLVPGPPGSSRPVKGQVVT :.. .: . ..: : : : : .: .: NP_001 YAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGE-GYSNPNEGATVE 120 130 140 150 160 130 140 150 160 170 180 pF1KB8 VHLQTSLENGTRVQEEPELVFTLG---DCDVIQALDLSVPLMDVGETAMVTADSKYCYGP .::. . : :. . ...::.: : :. ..: .. :. : .. .: .: NP_001 IHLEG--RCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGE 170 180 190 200 210 220 190 200 210 220 230 240 pF1KB8 QGSRSPYIPPHAALCLEVTLKTAVDGPDLEMLTGQERVALANRKRECGNAHYQRADFVLA :. . : :.: : :::::. . . . .:.. : .: :..... . .. : NP_001 AGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQA 230 240 250 260 270 280 250 260 270 280 290 300 pF1KB8 ANSYDLAIKAITSSAKVDMTFEEEAQLLQLKVKCLNNLAASQLKLDHYRAALRSCSLVLE . .: .. . . .. .: .. . . ::: ::: .: :.. :. .: NP_001 VIQYGKIVSWLE--MEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALG 290 300 310 320 330 340 310 320 330 340 350 360 pF1KB8 HQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKHAAQRSTE . : :.:.:.:.. ..:. : .. .:...:.::. . ..: :: . . NP_001 LDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERD 350 360 370 380 390 400 370 380 390 400 410 pF1KB8 TALYRKMLGNPSRLPAKCPGKGAWSIPWKWLFGATAVALGGVALSVVIAARN .: .:. . .. :: NP_001 RRIYANMFKKFAEQDAKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV 410 420 430 440 450 >>NP_001139248 (OMIM: 602623,608516) peptidyl-prolyl cis (457 aa) initn: 218 init1: 133 opt: 273 Z-score: 214.3 bits: 48.8 E(85289): 3.4e-05 Smith-Waterman score: 273; 23.7% identity (55.7% similar) in 287 aa overlap (95-378:141-422) 70 80 90 100 110 120 pF1KB8 EAEQPGALAREFLAAMEPEPAPAPAPEEWLDILGNGLLRKKTLVPGPPGSSRPVKGQVVT :.. .: . ..: : : : : .: .: NP_001 YAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGE-GYSNPNEGATVE 120 130 140 150 160 130 140 150 160 170 180 pF1KB8 VHLQTSLENGTRVQEEPELVFTLG---DCDVIQALDLSVPLMDVGETAMVTADSKYCYGP .::. . : :. . ...::.: : :. ..: .. :. : .. .: .: NP_001 IHLEG--RCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGE 170 180 190 200 210 220 190 200 210 220 230 240 pF1KB8 QGSRSPYIPPHAALCLEVTLKTAVDGPDLEMLTGQERVALANRKRECGNAHYQRADFVLA :. . : :.: : :::::. . . . .:.. : .: :..... . .. : NP_001 AGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQA 230 240 250 260 270 280 250 260 270 280 290 300 pF1KB8 ANSYDLAIKAITSSAKVDMTFEEEAQLLQLKVKCLNNLAASQLKLDHYRAALRSCSLVLE . .: .. . . .. .: .. . . ::: ::: .: :.. :. .: NP_001 VIQYGKIVSWLE--MEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALG 290 300 310 320 330 340 310 320 330 340 350 360 pF1KB8 HQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKHAAQRSTE . : :.:.:.:.. ..:. : .. .:...:.::. . ..: :: . . NP_001 LDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERD 350 360 370 380 390 400 370 380 390 400 410 pF1KB8 TALYRKMLGNPSRLPAKCPGKGAWSIPWKWLFGATAVALGGVALSVVIAARN .: .:. . .. :: NP_001 RRIYANMFKKFAEQDAKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV 410 420 430 440 450 >>NP_005029 (OMIM: 601753) peptidyl-prolyl cis-trans iso (370 aa) initn: 257 init1: 193 opt: 265 Z-score: 209.7 bits: 47.6 E(85289): 6.1e-05 Smith-Waterman score: 273; 27.8% identity (56.4% similar) in 266 aa overlap (106-369:135-369) 80 90 100 110 120 130 pF1KB8 FLAAMEPEPAPAPAPEEWLDILGNGLLRKKTLVPGPPGSSRPVK-GQVVT-VHLQTSLEN : :: : ... : :::. . . ::: NP_005 DENFHYKHDREGLLSMANAGRNTNGSQFFITTVPTPHLDGKHVVFGQVIKGIGVARILEN 110 120 130 140 150 160 140 150 160 170 180 190 pF1KB8 GTRVQEEPELVFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYGPQGSRSPYIPPHA :.: . ....: .. : : : . :.. :. : .: : NP_005 VEVKGEKPAKLCVIAECGELKEGD------DGG---IFPKDGS------GDSHPDFPEDA 170 180 190 200 200 210 220 230 240 250 pF1KB8 ALCLEVTLKTAVDGPDLEMLTGQERVALANRKRECGNAHYQRADFVLAANSYDLAIKAIT .. :: :: ..: : . .. ::. .. .. .: ..: ... . NP_005 ----DIDLKD-VD----KILLITEDL------KNIGNTFFKSQNWEMAIKKYAEVLRYVD 210 220 230 240 250 260 270 280 290 300 310 pF1KB8 SSAKVDMTFEEEAQLLQLKVKCLNNLAASQLKLDHYRAALRSCSLVLEHQPDNIKALFRK :: : : ..:.: . ..:. :..: .::......:. :: .:: .:.: :::.:. NP_005 SSKAVIET-ADRAKLQPIALSCVLNIGACKLKMSNWQGAIDSCLEALELDPSNTKALYRR 260 270 280 290 300 310 320 330 340 350 360 370 pF1KB8 GKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKHAAQRSTETALYRKMLGNPS .. ::..:. :. : . : .:.:.::: :. .: ::.. : :.: ::. NP_005 AQGWQGLKEYDQALADLKKAQGIAPEDKAIQAELLKVKQKIKAQKDKEKAVYAKMFA 320 330 340 350 360 370 380 390 400 410 pF1KB8 RLPAKCPGKGAWSIPWKWLFGATAVALGGVALSVVIAARN 413 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 01:35:39 2016 done: Sat Nov 5 01:35:41 2016 Total Scan time: 9.120 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]