FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8615, 488 aa 1>>>pF1KB8615 488 - 488 aa - 488 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.7450+/-0.000981; mu= 9.2186+/- 0.060 mean_var=164.4937+/-31.914, 0's: 0 Z-trim(110.6): 12 B-trim: 12 in 1/53 Lambda= 0.100000 statistics sampled from 11730 (11736) to 11730 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.708), E-opt: 0.2 (0.361), width: 16 Scan time: 2.920 The best scores are: opt bits E(32554) CCDS46484.1 SPATS2L gene_id:26010|Hs108|chr2 ( 489) 3186 471.6 8.6e-133 CCDS74622.1 SPATS2L gene_id:26010|Hs108|chr2 ( 498) 2237 334.7 1.4e-91 CCDS46483.1 SPATS2L gene_id:26010|Hs108|chr2 ( 558) 2237 334.7 1.6e-91 CCDS74621.1 SPATS2L gene_id:26010|Hs108|chr2 ( 588) 2237 334.7 1.6e-91 CCDS31794.1 SPATS2 gene_id:65244|Hs108|chr12 ( 545) 777 124.1 3.9e-28 >>CCDS46484.1 SPATS2L gene_id:26010|Hs108|chr2 (489 aa) initn: 2799 init1: 2799 opt: 3186 Z-score: 2497.5 bits: 471.6 E(32554): 8.6e-133 Smith-Waterman score: 3186; 99.8% identity (99.8% similar) in 489 aa overlap (1-488:1-489) 10 20 30 40 50 60 pF1KB8 MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MAELNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWN 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 MTGKK-NNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS ::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 ANEKPALIPREKKISILEEPSKALRGVTGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 ANEKPALIPREKKISILEEPSKALRGVTGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSS 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 VKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 VKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEM 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB8 QLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNNYSSRTPCSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 QLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNNYSSRTPCSS 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB8 LLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQTMPANKQNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 LLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQTMPANKQNG 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB8 SSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFRPKNKGGAKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFRPKNKGGAKN 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB8 QEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRIEVSTDAAVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 QEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRIEVSTDAAVL 430 440 450 460 470 480 480 pF1KB8 SVPAVTLVA ::::::::: CCDS46 SVPAVTLVA >>CCDS74622.1 SPATS2L gene_id:26010|Hs108|chr2 (498 aa) initn: 2274 init1: 2237 opt: 2237 Z-score: 1757.4 bits: 334.7 E(32554): 1.4e-91 Smith-Waterman score: 2659; 85.9% identity (85.9% similar) in 498 aa overlap (61-488:1-498) 40 50 60 70 80 pF1KB8 LVLQQFDFNVDKAVQAFVDGSAIQVLKEWNMTGKK-NNKRKRSKSKQHQGNKDAKDKVER ::::: :::::::::::::::::::::::: CCDS74 MTGKKKNNKRKRSKSKQHQGNKDAKDKVER 10 20 30 90 100 110 120 130 140 pF1KB8 PEAGPLQPQPPQIQNGPMNGCEKDSSSTDSANEKPALIPREKKISILEEPSKALRGVT-- :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 PEAGPLQPQPPQIQNGPMNGCEKDSSSTDSANEKPALIPREKKISILEEPSKALRGVTEG 40 50 60 70 80 90 pF1KB8 ------------------------------------------------------------ CCDS74 NRLLQQKLSLDGNPKPIHGTTERSDGLQWSAEQPCNPSKPKAKTSPVKSNTPAAHLEIKP 100 110 120 130 140 150 150 160 170 180 190 200 pF1KB8 -------GPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVS ::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 DELAKKRGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVS 160 170 180 190 200 210 210 220 230 240 250 260 pF1KB8 LMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEMQLAELRAEIKHFVSERKYDEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 LMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAEMQLAELRAEIKHFVSERKYDEE 220 230 240 250 260 270 270 280 290 300 310 320 pF1KB8 LGKAARFSCDIEQLKAQIMLCGEITHPKNNYSSRTPCSSLLPLLNAHAATSGKQSNFSRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 LGKAARFSCDIEQLKAQIMLCGEITHPKNNYSSRTPCSSLLPLLNAHAATSGKQSNFSRK 280 290 300 310 320 330 330 340 350 360 370 380 pF1KB8 SSTHNKPSEGKAANPKMVSSLPSTADPSHQTMPANKQNGSSNQRRRFNPQYHNNRLNGPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 SSTHNKPSEGKAANPKMVSSLPSTADPSHQTMPANKQNGSSNQRRRFNPQYHNNRLNGPA 340 350 360 370 380 390 390 400 410 420 430 440 pF1KB8 KSQGSGNEAEPLGKGNSRHEHRRQPHNGFRPKNKGGAKNQEASLGMKTPEAPAHSEKPRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 KSQGSGNEAEPLGKGNSRHEHRRQPHNGFRPKNKGGAKNQEASLGMKTPEAPAHSEKPRR 400 410 420 430 440 450 450 460 470 480 pF1KB8 RQHAADTSEARPFRGSVGRVSQCNLCPTRIEVSTDAAVLSVPAVTLVA :::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 RQHAADTSEARPFRGSVGRVSQCNLCPTRIEVSTDAAVLSVPAVTLVA 460 470 480 490 >>CCDS46483.1 SPATS2L gene_id:26010|Hs108|chr2 (558 aa) initn: 2653 init1: 2237 opt: 2237 Z-score: 1756.8 bits: 334.7 E(32554): 1.6e-91 Smith-Waterman score: 2802; 86.5% identity (86.5% similar) in 520 aa overlap (39-488:39-558) 10 20 30 40 50 60 pF1KB8 NVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWNMTGKK-NN ::::::::::::::::::::::::::: :: CCDS46 NVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWNMTGKKKNN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 KRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDSANEKPALI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 KRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDSANEKPALI 70 80 90 100 110 120 130 140 pF1KB8 PREKKISILEEPSKALRGVT---------------------------------------- :::::::::::::::::::: CCDS46 PREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSDGLQWSAEQPCNPS 130 140 150 160 170 180 150 160 170 pF1KB8 -----------------------------GPNIEKSVKDLQRCTVSLTRYRVMIKEEVDS ::::::::::::::::::::::::::::::: CCDS46 KPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDS 190 200 210 220 230 240 180 190 200 210 220 230 pF1KB8 SVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAE 250 260 270 280 290 300 240 250 260 270 280 290 pF1KB8 MQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNNYSSRTPCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNNYSSRTPCS 310 320 330 340 350 360 300 310 320 330 340 350 pF1KB8 SLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQTMPANKQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQTMPANKQN 370 380 390 400 410 420 360 370 380 390 400 410 pF1KB8 GSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFRPKNKGGAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 GSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFRPKNKGGAK 430 440 450 460 470 480 420 430 440 450 460 470 pF1KB8 NQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRIEVSTDAAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 NQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRIEVSTDAAV 490 500 510 520 530 540 480 pF1KB8 LSVPAVTLVA :::::::::: CCDS46 LSVPAVTLVA 550 >>CCDS74621.1 SPATS2L gene_id:26010|Hs108|chr2 (588 aa) initn: 2653 init1: 2237 opt: 2237 Z-score: 1756.4 bits: 334.7 E(32554): 1.6e-91 Smith-Waterman score: 2802; 86.5% identity (86.5% similar) in 520 aa overlap (39-488:69-588) 10 20 30 40 50 60 pF1KB8 NVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWNMTGKK-NN ::::::::::::::::::::::::::: :: CCDS74 NVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWNMTGKKKNN 40 50 60 70 80 90 70 80 90 100 110 120 pF1KB8 KRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDSANEKPALI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 KRKRSKSKQHQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCEKDSSSTDSANEKPALI 100 110 120 130 140 150 130 140 pF1KB8 PREKKISILEEPSKALRGVT---------------------------------------- :::::::::::::::::::: CCDS74 PREKKISILEEPSKALRGVTEGNRLLQQKLSLDGNPKPIHGTTERSDGLQWSAEQPCNPS 160 170 180 190 200 210 150 160 170 pF1KB8 -----------------------------GPNIEKSVKDLQRCTVSLTRYRVMIKEEVDS ::::::::::::::::::::::::::::::: CCDS74 KPKAKTSPVKSNTPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDS 220 230 240 250 260 270 180 190 200 210 220 230 pF1KB8 SVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 SVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLASQMAE 280 290 300 310 320 330 240 250 260 270 280 290 pF1KB8 MQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNNYSSRTPCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 MQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNNYSSRTPCS 340 350 360 370 380 390 300 310 320 330 340 350 pF1KB8 SLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQTMPANKQN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 SLLPLLNAHAATSGKQSNFSRKSSTHNKPSEGKAANPKMVSSLPSTADPSHQTMPANKQN 400 410 420 430 440 450 360 370 380 390 400 410 pF1KB8 GSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFRPKNKGGAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 GSSNQRRRFNPQYHNNRLNGPAKSQGSGNEAEPLGKGNSRHEHRRQPHNGFRPKNKGGAK 460 470 480 490 500 510 420 430 440 450 460 470 pF1KB8 NQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRIEVSTDAAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 NQEASLGMKTPEAPAHSEKPRRRQHAADTSEARPFRGSVGRVSQCNLCPTRIEVSTDAAV 520 530 540 550 560 570 480 pF1KB8 LSVPAVTLVA :::::::::: CCDS74 LSVPAVTLVA 580 >>CCDS31794.1 SPATS2 gene_id:65244|Hs108|chr12 (545 aa) initn: 1084 init1: 710 opt: 777 Z-score: 618.5 bits: 124.1 E(32554): 3.9e-28 Smith-Waterman score: 873; 37.8% identity (63.2% similar) in 497 aa overlap (34-447:56-540) 10 20 30 40 50 60 pF1KB8 LNTHVNVKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWNMTG :.:: :::.::::..::: .:::::..:: CCDS31 GGAFENMKEKINAVRAIVPNKSNNEIILVLQHFDNCVDKTVQAFMEGSASEVLKEWTVTG 30 40 50 60 70 80 70 80 90 100 110 pF1KB8 KKNNKRKRSKSKQ----HQGNKDAKDKVERPEAGPLQPQPPQIQNGPMNGCE-----KDS ::.::.:..: : .: :.. .: : . . :. ..: ::: . .:. CCDS31 KKKNKKKKNKPKPAAEPSNGIPDSSKSVSIQE----EQSAPSSEKGGMNGYHVNGAINDT 90 100 110 120 130 140 120 130 pF1KB8 SSTDSANE---------------KPALIPR-EKKISILE--------------------E :.:: .: . :.. .. :.:. . CCDS31 ESVDSLSEGLETLSIDARELEDPESAMLDTLDRTGSMLQNGVSDFETKSLTMHSIHNSQQ 150 160 170 180 190 200 140 150 160 170 pF1KB8 PSKALRGVTGP------------------------NIEKSVKDLQRCTVSLTRYRVMIKE : .: .... : ::::::::::::::::.::::..:: CCDS31 PRNAAKSLSRPTTETQFSNMGMEDVPLATSKKLSSNIEKSVKDLQRCTVSLARYRVVVKE 210 220 230 240 250 260 180 190 200 210 220 230 pF1KB8 EVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMEILTARQKKAEELKRLTDLAS :.:.:.::.: :::::..:..:.::.:.::::::: :::::: .:::::: ::..: .: CCDS31 EMDASIKKMKQAFAELESCLMDREVALLAEMDKVKAEAMEILLSRQKKAELLKKMTHVAV 270 280 290 300 310 320 240 250 260 270 280 290 pF1KB8 QMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQIMLCGEITHPKNNYSSR ::.:.::.::::.::::::::::::.::..:::.::.: :: .: :...::::.::.: CCDS31 QMSEQQLVELRADIKHFVSERKYDEDLGRVARFTCDVETLKKSIDSFGQVSHPKNSYSTR 330 340 350 360 370 380 300 310 320 330 340 pF1KB8 TPCSSLLPLL-----NAHAATSGKQSNFSRKSSTHNK---PSEGKAANPKMVSSLPSTAD . :::. . .: ::.:. .. .:...: :.: :: ...: . . CCDS31 SRCSSVTSVSLSSPSDASAASSSTCASPPSLTSANKKNFAPGETPAA---IANSSGQPYQ 390 400 410 420 430 350 360 370 380 390 400 pF1KB8 PSHQTMPANKQNGSSNQRRRFNPQYHNNRLN-GPAKSQGSGNEAEPLGKGNSRHEH--RR : ....:.:...: : : . : :. .: : :.: .. ..: ::.. . CCDS31 PLREVLPGNRRGG---QGYRPQGQKSNDPMNQGRHDSMGRYRNSSWYSSG-SRYQSAPSQ 440 450 460 470 480 490 410 420 430 440 450 460 pF1KB8 QPHNGFRPKNKGGAKNQEASLGMKTPEAPAHSEK---PRRRQHAADTSEARPFRGSVGRV : : .. . .: .. ....:. : :. : : :.:. ....: CCDS31 APGNTIERGQTHSAGTNGTGVSME-PSPPTPSFKKGLPQRKPRTSQTEAVNS 500 510 520 530 540 470 480 pF1KB8 SQCNLCPTRIEVSTDAAVLSVPAVTLVA 488 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 13:40:43 2016 done: Fri Nov 4 13:40:44 2016 Total Scan time: 2.920 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]