FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8616, 368 aa 1>>>pF1KB8616 368 - 368 aa - 368 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.9512+/-0.00083; mu= 9.4613+/- 0.050 mean_var=106.7940+/-20.723, 0's: 0 Z-trim(110.5): 14 B-trim: 81 in 1/52 Lambda= 0.124108 statistics sampled from 11619 (11625) to 11619 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.357), width: 16 Scan time: 2.880 The best scores are: opt bits E(32554) CCDS32252.1 POLR2M gene_id:81488|Hs108|chr15 ( 368) 2413 442.4 3e-124 CCDS73732.1 GCOM1 gene_id:145781|Hs108|chr15 ( 765) 2167 398.5 1e-110 CCDS42045.1 POLR2M gene_id:81488|Hs108|chr15 ( 211) 1137 213.8 1.1e-55 CCDS32247.1 GCOM1 gene_id:145781|Hs108|chr15 ( 550) 764 147.2 3.2e-35 >>CCDS32252.1 POLR2M gene_id:81488|Hs108|chr15 (368 aa) initn: 2413 init1: 2413 opt: 2413 Z-score: 2344.1 bits: 442.4 E(32554): 3e-124 Smith-Waterman score: 2413; 100.0% identity (100.0% similar) in 368 aa overlap (1-368:1-368) 10 20 30 40 50 60 pF1KB8 MCSLPRGFEPQAPEDLAQRSLVELREMLKRQERLLRNEKFICKLPDKGKKIFDSFAKLKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MCSLPRGFEPQAPEDLAQRSLVELREMLKRQERLLRNEKFICKLPDKGKKIFDSFAKLKA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 AIAECEEVRRKSELFNPVSLDCKLRQKAIAEVDVGTDKAQNSDPILDTSSLVPGCSSVDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 AIAECEEVRRKSELFNPVSLDCKLRQKAIAEVDVGTDKAQNSDPILDTSSLVPGCSSVDN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 IKSSQTSQNQGLGRPTLEGDEETSEVEYTVNKGPASSNRDRVPPSSEASEHHPRHRVSSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 IKSSQTSQNQGLGRPTLEGDEETSEVEYTVNKGPASSNRDRVPPSSEASEHHPRHRVSSQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 AEDTSSSFDNLFIDRLQRITIADQGEQQSEENASTKNLTGLSSGTEKKPHYMEVLEMRAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 AEDTSSSFDNLFIDRLQRITIADQGEQQSEENASTKNLTGLSSGTEKKPHYMEVLEMRAK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 NPVPQLRKFKTNVLPFRQNDSSSHCQKSGSPISSEERRRRDKQHLDDITAARLLPLHHMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 NPVPQLRKFKTNVLPFRQNDSSSHCQKSGSPISSEERRRRDKQHLDDITAARLLPLHHMP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 TQLLSIEESLALQKQQKQNYEEMQAKLAAQKLAERLNIKMRSYNPEGESSGRYREVRDED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 TQLLSIEESLALQKQQKQNYEEMQAKLAAQKLAERLNIKMRSYNPEGESSGRYREVRDED 310 320 330 340 350 360 pF1KB8 DDWSSDEF :::::::: CCDS32 DDWSSDEF >>CCDS73732.1 GCOM1 gene_id:145781|Hs108|chr15 (765 aa) initn: 2160 init1: 2160 opt: 2167 Z-score: 2101.1 bits: 398.5 E(32554): 1e-110 Smith-Waterman score: 2167; 96.0% identity (97.1% similar) in 350 aa overlap (19-368:418-765) 10 20 30 40 pF1KB8 MCSLPRGFEPQAPEDLAQRSLVELREMLKRQERLLRNEKFICKLPDKG .. :: ::. . : : :::::::::: CCDS73 ILQLLEKISFLEGENNELQSRLDYLTETQAKTEVETREIGVGCDLLPR--KFICKLPDKG 390 400 410 420 430 440 50 60 70 80 90 100 pF1KB8 KKIFDSFAKLKAAIAECEEVRRKSELFNPVSLDCKLRQKAIAEVDVGTDKAQNSDPILDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 KKIFDSFAKLKAAIAECEEVRRKSELFNPVSLDCKLRQKAIAEVDVGTDKAQNSDPILDT 450 460 470 480 490 500 110 120 130 140 150 160 pF1KB8 SSLVPGCSSVDNIKSSQTSQNQGLGRPTLEGDEETSEVEYTVNKGPASSNRDRVPPSSEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 SSLVPGCSSVDNIKSSQTSQNQGLGRPTLEGDEETSEVEYTVNKGPASSNRDRVPPSSEA 510 520 530 540 550 560 170 180 190 200 210 220 pF1KB8 SEHHPRHRVSSQAEDTSSSFDNLFIDRLQRITIADQGEQQSEENASTKNLTGLSSGTEKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 SEHHPRHRVSSQAEDTSSSFDNLFIDRLQRITIADQGEQQSEENASTKNLTGLSSGTEKK 570 580 590 600 610 620 230 240 250 260 270 280 pF1KB8 PHYMEVLEMRAKNPVPQLRKFKTNVLPFRQNDSSSHCQKSGSPISSEERRRRDKQHLDDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 PHYMEVLEMRAKNPVPQLRKFKTNVLPFRQNDSSSHCQKSGSPISSEERRRRDKQHLDDI 630 640 650 660 670 680 290 300 310 320 330 340 pF1KB8 TAARLLPLHHMPTQLLSIEESLALQKQQKQNYEEMQAKLAAQKLAERLNIKMRSYNPEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 TAARLLPLHHMPTQLLSIEESLALQKQQKQNYEEMQAKLAAQKLAERLNIKMRSYNPEGE 690 700 710 720 730 740 350 360 pF1KB8 SSGRYREVRDEDDDWSSDEF :::::::::::::::::::: CCDS73 SSGRYREVRDEDDDWSSDEF 750 760 >>CCDS42045.1 POLR2M gene_id:81488|Hs108|chr15 (211 aa) initn: 1137 init1: 1137 opt: 1137 Z-score: 1113.1 bits: 213.8 E(32554): 1.1e-55 Smith-Waterman score: 1137; 96.7% identity (98.9% similar) in 180 aa overlap (189-368:32-211) 160 170 180 190 200 210 pF1KB8 RDRVPPSSEASEHHPRHRVSSQAEDTSSSFDNLFIDRLQRITIADQGEQQSEENASTKNL . :. ..::::::::::::::::::::::: CCDS42 CSLPRGFEPQAPEDLAQRSLVELREMLKRQERLLRNELQRITIADQGEQQSEENASTKNL 10 20 30 40 50 60 220 230 240 250 260 270 pF1KB8 TGLSSGTEKKPHYMEVLEMRAKNPVPQLRKFKTNVLPFRQNDSSSHCQKSGSPISSEERR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 TGLSSGTEKKPHYMEVLEMRAKNPVPQLRKFKTNVLPFRQNDSSSHCQKSGSPISSEERR 70 80 90 100 110 120 280 290 300 310 320 330 pF1KB8 RRDKQHLDDITAARLLPLHHMPTQLLSIEESLALQKQQKQNYEEMQAKLAAQKLAERLNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 RRDKQHLDDITAARLLPLHHMPTQLLSIEESLALQKQQKQNYEEMQAKLAAQKLAERLNI 130 140 150 160 170 180 340 350 360 pF1KB8 KMRSYNPEGESSGRYREVRDEDDDWSSDEF :::::::::::::::::::::::::::::: CCDS42 KMRSYNPEGESSGRYREVRDEDDDWSSDEF 190 200 210 >>CCDS32247.1 GCOM1 gene_id:145781|Hs108|chr15 (550 aa) initn: 764 init1: 764 opt: 764 Z-score: 745.7 bits: 147.2 E(32554): 3.2e-35 Smith-Waterman score: 764; 100.0% identity (100.0% similar) in 115 aa overlap (254-368:436-550) 230 240 250 260 270 280 pF1KB8 GTEKKPHYMEVLEMRAKNPVPQLRKFKTNVLPFRQNDSSSHCQKSGSPISSEERRRRDKQ :::::::::::::::::::::::::::::: CCDS32 QSRLDYLTETQAKTEVETREIGVGCDLLPRLPFRQNDSSSHCQKSGSPISSEERRRRDKQ 410 420 430 440 450 460 290 300 310 320 330 340 pF1KB8 HLDDITAARLLPLHHMPTQLLSIEESLALQKQQKQNYEEMQAKLAAQKLAERLNIKMRSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 HLDDITAARLLPLHHMPTQLLSIEESLALQKQQKQNYEEMQAKLAAQKLAERLNIKMRSY 470 480 490 500 510 520 350 360 pF1KB8 NPEGESSGRYREVRDEDDDWSSDEF ::::::::::::::::::::::::: CCDS32 NPEGESSGRYREVRDEDDDWSSDEF 530 540 550 368 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 21:46:51 2016 done: Sat Nov 5 21:46:52 2016 Total Scan time: 2.880 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]