Result of FASTA (ccds) for
pF1KB8620
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8620, 184 aa
1>>>pF1KB8620 184 - 184 aa - 184 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9729+/-0.00104; mu= 14.7868+/- 0.063
mean_var=75.6888+/-15.144, 0's: 0 Z-trim(105.5): 194 B-trim: 324 in 1/48
Lambda= 0.147421
statistics sampled from 8246 (8464) to 8246 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.643), E-opt: 0.2 (0.26), width: 16
Scan time: 1.770
The best scores are: opt bits E(32554)
CCDS8984.1 RAP1B gene_id:5908|Hs108|chr12 ( 184) 1200 264.4 2.9e-71
CCDS840.1 RAP1A gene_id:5906|Hs108|chr1 ( 184) 1128 249.1 1.2e-66
CCDS58253.1 RAP1B gene_id:5908|Hs108|chr12 ( 165) 816 182.7 1e-46
CCDS58254.1 RAP1B gene_id:5908|Hs108|chr12 ( 142) 810 181.3 2.2e-46
CCDS3170.1 RAP2B gene_id:5912|Hs108|chr3 ( 183) 741 166.8 6.9e-42
CCDS9485.1 RAP2A gene_id:5911|Hs108|chr13 ( 183) 731 164.6 3e-41
CCDS14632.1 RAP2C gene_id:57826|Hs108|chrX ( 183) 731 164.6 3e-41
CCDS8702.1 KRAS gene_id:3845|Hs108|chr12 ( 188) 671 151.9 2.1e-37
CCDS8703.1 KRAS gene_id:3845|Hs108|chr12 ( 189) 654 148.3 2.6e-36
CCDS7698.1 HRAS gene_id:3265|Hs108|chr11 ( 189) 650 147.4 4.8e-36
CCDS877.1 NRAS gene_id:4893|Hs108|chr1 ( 189) 639 145.1 2.4e-35
CCDS7814.1 RRAS2 gene_id:22800|Hs108|chr11 ( 204) 614 139.8 1e-33
CCDS7699.1 HRAS gene_id:3265|Hs108|chr11 ( 170) 608 138.4 2.1e-33
CCDS3100.1 MRAS gene_id:22808|Hs108|chr3 ( 208) 596 136.0 1.5e-32
CCDS5460.1 RALA gene_id:5898|Hs108|chr7 ( 206) 585 133.6 7.3e-32
CCDS1123.1 RIT1 gene_id:6016|Hs108|chr1 ( 219) 584 133.4 8.9e-32
CCDS58037.1 RIT1 gene_id:6016|Hs108|chr1 ( 236) 584 133.5 9.4e-32
CCDS11921.1 RIT2 gene_id:6014|Hs108|chr18 ( 217) 574 131.3 3.9e-31
CCDS12774.1 RRAS gene_id:6237|Hs108|chr19 ( 218) 560 128.3 3.1e-30
CCDS2131.1 RALB gene_id:5899|Hs108|chr2 ( 206) 556 127.5 5.3e-30
CCDS58252.1 RAP1B gene_id:5908|Hs108|chr12 ( 137) 523 120.3 5.1e-28
CCDS6687.1 DIRAS2 gene_id:54769|Hs108|chr9 ( 199) 519 119.6 1.2e-27
CCDS12092.1 DIRAS1 gene_id:148252|Hs108|chr19 ( 198) 496 114.7 3.6e-26
CCDS53603.1 RRAS2 gene_id:22800|Hs108|chr11 ( 169) 494 114.2 4.3e-26
CCDS8673.1 RERG gene_id:85004|Hs108|chr12 ( 199) 490 113.4 8.7e-26
CCDS58036.1 RIT1 gene_id:6016|Hs108|chr1 ( 183) 487 112.7 1.3e-25
CCDS62431.1 RIT2 gene_id:6014|Hs108|chr18 ( 153) 446 103.9 4.7e-23
CCDS5927.1 RHEB gene_id:6009|Hs108|chr7 ( 184) 441 103.0 1.1e-22
CCDS76024.1 RAP2C gene_id:57826|Hs108|chrX ( 117) 391 92.1 1.3e-19
CCDS8778.1 RHEBL1 gene_id:121268|Hs108|chr12 ( 183) 389 91.9 2.4e-19
CCDS35246.1 ERAS gene_id:3266|Hs108|chrX ( 233) 379 89.9 1.2e-18
CCDS42410.1 RAB12 gene_id:201475|Hs108|chr18 ( 244) 373 88.6 3.1e-18
CCDS53753.1 RERG gene_id:85004|Hs108|chr12 ( 180) 369 87.6 4.5e-18
CCDS10183.1 RAB8B gene_id:51762|Hs108|chr15 ( 207) 367 87.3 6.7e-18
CCDS3976.1 RAB3C gene_id:115827|Hs108|chr5 ( 227) 367 87.3 7.1e-18
CCDS1058.1 RAB13 gene_id:5872|Hs108|chr1 ( 203) 365 86.8 8.8e-18
CCDS641.1 DIRAS3 gene_id:9077|Hs108|chr1 ( 229) 363 86.5 1.3e-17
CCDS1720.1 RAB10 gene_id:10890|Hs108|chr2 ( 200) 361 86.0 1.6e-17
CCDS9570.1 RAB2B gene_id:84932|Hs108|chr14 ( 216) 354 84.5 4.7e-17
CCDS12339.1 RAB8A gene_id:4218|Hs108|chr19 ( 207) 353 84.3 5.3e-17
CCDS560.1 RAB3B gene_id:5865|Hs108|chr1 ( 219) 353 84.3 5.5e-17
CCDS12372.1 RAB3A gene_id:5864|Hs108|chr19 ( 220) 353 84.3 5.5e-17
CCDS44544.1 RRAS2 gene_id:22800|Hs108|chr11 ( 127) 344 82.2 1.4e-16
CCDS6175.1 RAB2A gene_id:5862|Hs108|chr8 ( 212) 346 82.8 1.5e-16
CCDS12257.1 RAB3D gene_id:9545|Hs108|chr19 ( 219) 344 82.4 2.1e-16
CCDS4962.1 RAB23 gene_id:51715|Hs108|chr6 ( 237) 343 82.2 2.5e-16
CCDS11703.1 RAB37 gene_id:326624|Hs108|chr17 ( 216) 342 82.0 2.7e-16
CCDS11419.1 RAB5C gene_id:5878|Hs108|chr17 ( 216) 341 81.7 3.2e-16
CCDS58551.1 RAB5C gene_id:5878|Hs108|chr17 ( 249) 341 81.8 3.5e-16
CCDS46306.1 RAB1A gene_id:5861|Hs108|chr2 ( 205) 340 81.5 3.5e-16
>>CCDS8984.1 RAP1B gene_id:5908|Hs108|chr12 (184 aa)
initn: 1200 init1: 1200 opt: 1200 Z-score: 1393.0 bits: 264.4 E(32554): 2.9e-71
Smith-Waterman score: 1200; 100.0% identity (100.0% similar) in 184 aa overlap (1-184:1-184)
10 20 30 40 50 60
pF1KB8 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS89 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS89 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS89 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS
130 140 150 160 170 180
pF1KB8 CQLL
::::
CCDS89 CQLL
>>CCDS840.1 RAP1A gene_id:5906|Hs108|chr1 (184 aa)
initn: 1128 init1: 1128 opt: 1128 Z-score: 1310.3 bits: 249.1 E(32554): 1.2e-66
Smith-Waterman score: 1128; 95.1% identity (96.2% similar) in 184 aa overlap (1-184:1-184)
10 20 30 40 50 60
pF1KB8 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG
::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
CCDS84 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
CCDS84 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS
:::::::::::::::::: :::::::::::::::::::::::::::::::: : ::.:
CCDS84 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS
130 140 150 160 170 180
pF1KB8 CQLL
: ::
CCDS84 CLLL
>>CCDS58253.1 RAP1B gene_id:5908|Hs108|chr12 (165 aa)
initn: 1066 init1: 810 opt: 816 Z-score: 952.3 bits: 182.7 E(32554): 1e-46
Smith-Waterman score: 1030; 89.7% identity (89.7% similar) in 184 aa overlap (1-184:1-165)
10 20 30 40 50 60
pF1KB8 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG
::::::::::::::::::::::::::::::::::::::::::
CCDS58 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRK------------------
10 20 30 40
70 80 90 100 110 120
pF1KB8 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 -EQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB8 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS
110 120 130 140 150 160
pF1KB8 CQLL
::::
CCDS58 CQLL
>>CCDS58254.1 RAP1B gene_id:5908|Hs108|chr12 (142 aa)
initn: 913 init1: 810 opt: 810 Z-score: 946.2 bits: 181.3 E(32554): 2.2e-46
Smith-Waterman score: 833; 77.2% identity (77.2% similar) in 184 aa overlap (1-184:1-142)
10 20 30 40 50 60
pF1KB8 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG
:::::::::::::::::::
CCDS58 MREYKLVVLGSGGVGKSAL-----------------------------------------
10
70 80 90 100 110 120
pF1KB8 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 -EQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL
20 30 40 50 60 70
130 140 150 160 170 180
pF1KB8 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS58 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS
80 90 100 110 120 130
pF1KB8 CQLL
::::
CCDS58 CQLL
140
>>CCDS3170.1 RAP2B gene_id:5912|Hs108|chr3 (183 aa)
initn: 696 init1: 634 opt: 741 Z-score: 865.5 bits: 166.8 E(32554): 6.9e-42
Smith-Waterman score: 741; 61.4% identity (82.6% similar) in 184 aa overlap (1-184:1-183)
10 20 30 40 50 60
pF1KB8 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG
:::::.:::::::::::::::::: : :.::::::::: :::..:::.. .::::::::
CCDS31 MREYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL
::::..:::::.:::::: ::::.. :..:.:.. .:.::.::: . ::::::::: ::
CCDS31 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS
: :: :. .:. ::..:. : :.:.:::.: .:.:.: ..:::.: . : :.
CCDS31 EGEREVSYGEGKALAEEWS-CPFMETSAKNKASVDELFAEIVRQMNYAAQPNGDEGCCSA
130 140 150 160 170
pF1KB8 CQLL
: .:
CCDS31 CVIL
180
>>CCDS9485.1 RAP2A gene_id:5911|Hs108|chr13 (183 aa)
initn: 697 init1: 634 opt: 731 Z-score: 854.0 bits: 164.6 E(32554): 3e-41
Smith-Waterman score: 731; 61.4% identity (83.7% similar) in 184 aa overlap (1-183:1-182)
10 20 30 40 50 60
pF1KB8 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG
:::::.:::::::::::::::::: : :.::::::::: :::..:::.. .::::::::
CCDS94 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL
::::..:::::.:::::: ::::.. :..:.:.. .:.::.::: . ::.:::::: ::
CCDS94 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDL
70 80 90 100 110 120
130 140 150 160 170
pF1KB8 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKK-S
:.:: :.. .:. ::..:. : :.:.::::: :.:.: ..:::.: . : : :
CCDS94 ESEREVSSSEGRALAEEWG-CPFMETSAKSKTMVDELFAEIVRQMNYAAQ-PDKDDPCCS
130 140 150 160 170
180
pF1KB8 SCQLL
.:..
CCDS94 ACNIQ
180
>>CCDS14632.1 RAP2C gene_id:57826|Hs108|chrX (183 aa)
initn: 694 init1: 632 opt: 731 Z-score: 854.0 bits: 164.6 E(32554): 3e-41
Smith-Waterman score: 731; 61.9% identity (85.1% similar) in 181 aa overlap (1-181:1-176)
10 20 30 40 50 60
pF1KB8 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG
:::::.:::::::::::::::::: : :.::::::::: :::..:::.. .::::::::
CCDS14 MREYKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL
::::..:::::.:::::: ::::.. :..:.:.. .:.::.::: . ::.:::::: ::
CCDS14 TEQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS
: :: : . .:. ::..:. : :.:.::::: :.:.: ..:::.: .. .: .:...
CCDS14 EPEREVMSSEGRALAQEWG-CPFMETSAKSKSMVDELFAEIVRQMNYSS-LP---EKQDQ
130 140 150 160 170
pF1KB8 CQLL
:
CCDS14 CCTTCVVQ
180
>>CCDS8702.1 KRAS gene_id:3845|Hs108|chr12 (188 aa)
initn: 651 init1: 556 opt: 671 Z-score: 784.8 bits: 151.9 E(32554): 2.1e-37
Smith-Waterman score: 671; 55.7% identity (82.5% similar) in 183 aa overlap (1-180:1-181)
10 20 30 40 50 60
pF1KB8 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG
: ::::::.:.:::::::::.:..:. ::..::::::::::::: .:.. :.:.::::::
CCDS87 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL
:...:::: ::..:.:: :..:. ..:.:.. :::: ::::..::::.::::::::
CCDS87 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL
70 80 90 100 110 120
130 140 150 160 170
pF1KB8 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINR---KTPVPGKARK
. :.: .:.:.:::... :.:.:::.. .:.. :: :::.: . : :: .:
CCDS87 PS-RTVDTKQAQDLARSYG-IPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKK
130 140 150 160 170
180
pF1KB8 KSSCQLL
:.:
CCDS87 KKSKTKCVIM
180
>>CCDS8703.1 KRAS gene_id:3845|Hs108|chr12 (189 aa)
initn: 618 init1: 548 opt: 654 Z-score: 765.3 bits: 148.3 E(32554): 2.6e-36
Smith-Waterman score: 654; 54.4% identity (81.9% similar) in 182 aa overlap (1-181:1-180)
10 20 30 40 50 60
pF1KB8 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG
: ::::::.:.:::::::::.:..:. ::..::::::::::::: .:.. :.:.::::::
CCDS87 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL
:...:::: ::..:.:: :..:. ..:.:.. :::: ::::..::::.::::::::
CCDS87 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL
70 80 90 100 110 120
130 140 150 160 170
pF1KB8 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINR-KTPVPGKARKKS
. :.: .:.:.:::... :.:.:::.. :.. :: :::.: . . .: .:
CCDS87 PS-RTVDTKQAQDLARSYG-IPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTP
130 140 150 160 170
180
pF1KB8 SCQLL
.:
CCDS87 GCVKIKKCIIM
180
>>CCDS7698.1 HRAS gene_id:3265|Hs108|chr11 (189 aa)
initn: 604 init1: 555 opt: 650 Z-score: 760.7 bits: 147.4 E(32554): 4.8e-36
Smith-Waterman score: 650; 58.2% identity (86.7% similar) in 165 aa overlap (1-165:1-163)
10 20 30 40 50 60
pF1KB8 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG
: ::::::.:.:::::::::.:..:. ::..::::::::::::: .:.. :.:.::::::
CCDS76 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL
:...:::: ::..:.:: :..:. ..:.:... :::: ::::.:::::.::::::::
CCDS76 QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS
:.: ..:.:.:::... ..:.:::.. .:.. :: :::.:
CCDS76 A-ARTVESRQAQDLARSYG-IPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESG
130 140 150 160 170
pF1KB8 CQLL
CCDS76 PGCMSCKCVLS
180
184 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 13:42:46 2016 done: Fri Nov 4 13:42:46 2016
Total Scan time: 1.770 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]