FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8620, 184 aa 1>>>pF1KB8620 184 - 184 aa - 184 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5775+/-0.000438; mu= 11.3019+/- 0.027 mean_var=79.8550+/-15.759, 0's: 0 Z-trim(112.2): 432 B-trim: 609 in 1/54 Lambda= 0.143524 statistics sampled from 20590 (21088) to 20590 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.63), E-opt: 0.2 (0.247), width: 16 Scan time: 4.200 The best scores are: opt bits E(85289) NP_001010942 (OMIM: 179530) ras-related protein Ra ( 184) 1200 258.0 6.2e-69 NP_056461 (OMIM: 179530) ras-related protein Rap-1 ( 184) 1200 258.0 6.2e-69 NP_002875 (OMIM: 179520) ras-related protein Rap-1 ( 184) 1128 243.1 1.9e-64 NP_001278825 (OMIM: 179520) ras-related protein Ra ( 184) 1128 243.1 1.9e-64 XP_016857452 (OMIM: 179520) PREDICTED: ras-related ( 184) 1128 243.1 1.9e-64 XP_016857451 (OMIM: 179520) PREDICTED: ras-related ( 184) 1128 243.1 1.9e-64 XP_016857453 (OMIM: 179520) PREDICTED: ras-related ( 184) 1128 243.1 1.9e-64 NP_001010935 (OMIM: 179520) ras-related protein Ra ( 184) 1128 243.1 1.9e-64 XP_016857450 (OMIM: 179520) PREDICTED: ras-related ( 195) 1005 217.6 9.3e-57 XP_016857449 (OMIM: 179520) PREDICTED: ras-related ( 195) 1005 217.6 9.3e-57 NP_001238850 (OMIM: 179530) ras-related protein Ra ( 165) 816 178.5 4.9e-45 NP_001238846 (OMIM: 179530) ras-related protein Ra ( 142) 810 177.2 1e-44 NP_001238847 (OMIM: 179530) ras-related protein Ra ( 142) 810 177.2 1e-44 NP_002877 (OMIM: 179541) ras-related protein Rap-2 ( 183) 741 163.0 2.5e-40 NP_066361 (OMIM: 179540) ras-related protein Rap-2 ( 183) 731 160.9 1.1e-39 NP_004976 (OMIM: 109800,114480,137215,163200,19007 ( 188) 671 148.5 5.9e-36 XP_011518955 (OMIM: 109800,114480,137215,163200,19 ( 188) 671 148.5 5.9e-36 NP_203524 (OMIM: 109800,114480,137215,163200,19007 ( 189) 654 145.0 6.8e-35 XP_006719132 (OMIM: 109800,114480,137215,163200,19 ( 189) 654 145.0 6.8e-35 XP_016874782 (OMIM: 109800,114480,137215,163200,19 ( 227) 654 145.0 7.9e-35 NP_005334 (OMIM: 109800,137550,162900,163200,18847 ( 189) 650 144.1 1.2e-34 NP_001123914 (OMIM: 109800,137550,162900,163200,18 ( 189) 650 144.1 1.2e-34 NP_002515 (OMIM: 114500,137550,162900,163200,16479 ( 189) 639 141.9 5.9e-34 NP_036382 (OMIM: 600098) ras-related protein R-Ras ( 204) 614 136.7 2.3e-32 NP_789765 (OMIM: 109800,137550,162900,163200,18847 ( 170) 608 135.4 4.6e-32 NP_036351 (OMIM: 608435) ras-related protein M-Ras ( 208) 596 133.0 3e-31 NP_001239019 (OMIM: 608435) ras-related protein M- ( 208) 596 133.0 3e-31 XP_005247285 (OMIM: 608435) PREDICTED: ras-related ( 208) 596 133.0 3e-31 XP_016861376 (OMIM: 608435) PREDICTED: ras-related ( 208) 596 133.0 3e-31 NP_001078518 (OMIM: 608435) ras-related protein M- ( 208) 596 133.0 3e-31 NP_005393 (OMIM: 179550) ras-related protein Ral-A ( 206) 585 130.7 1.5e-30 XP_006715825 (OMIM: 179550) PREDICTED: ras-related ( 206) 585 130.7 1.5e-30 XP_011513768 (OMIM: 179550) PREDICTED: ras-related ( 206) 585 130.7 1.5e-30 NP_008843 (OMIM: 609591,615355) GTP-binding protei ( 219) 584 130.5 1.8e-30 NP_001243750 (OMIM: 609591,615355) GTP-binding pro ( 236) 584 130.5 1.9e-30 NP_002921 (OMIM: 609592) GTP-binding protein Rit2 ( 217) 574 128.4 7.4e-30 NP_006261 (OMIM: 165090) ras-related protein R-Ras ( 218) 560 125.5 5.5e-29 XP_016860111 (OMIM: 179551) PREDICTED: ras-related ( 206) 556 124.7 9.4e-29 XP_005263784 (OMIM: 179551) PREDICTED: ras-related ( 206) 556 124.7 9.4e-29 XP_005263786 (OMIM: 179551) PREDICTED: ras-related ( 206) 556 124.7 9.4e-29 NP_002872 (OMIM: 179551) ras-related protein Ral-B ( 206) 556 124.7 9.4e-29 XP_005263785 (OMIM: 179551) PREDICTED: ras-related ( 206) 556 124.7 9.4e-29 XP_016860110 (OMIM: 179551) PREDICTED: ras-related ( 228) 556 124.7 1e-28 XP_005263781 (OMIM: 179551) PREDICTED: ras-related ( 228) 556 124.7 1e-28 XP_011509875 (OMIM: 179551) PREDICTED: ras-related ( 229) 556 124.7 1e-28 NP_001238851 (OMIM: 179530) ras-related protein Ra ( 137) 523 117.7 7.7e-27 NP_060064 (OMIM: 607863) GTP-binding protein Di-Ra ( 199) 519 117.0 1.9e-26 XP_005247286 (OMIM: 608435) PREDICTED: ras-related ( 170) 512 115.5 4.5e-26 XP_016872852 (OMIM: 600098) PREDICTED: ras-related ( 182) 500 113.1 2.6e-25 NP_660156 (OMIM: 607862) GTP-binding protein Di-Ra ( 198) 496 112.3 5e-25 >>NP_001010942 (OMIM: 179530) ras-related protein Rap-1b (184 aa) initn: 1200 init1: 1200 opt: 1200 Z-score: 1358.6 bits: 258.0 E(85289): 6.2e-69 Smith-Waterman score: 1200; 100.0% identity (100.0% similar) in 184 aa overlap (1-184:1-184) 10 20 30 40 50 60 pF1KB8 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS 130 140 150 160 170 180 pF1KB8 CQLL :::: NP_001 CQLL >>NP_056461 (OMIM: 179530) ras-related protein Rap-1b is (184 aa) initn: 1200 init1: 1200 opt: 1200 Z-score: 1358.6 bits: 258.0 E(85289): 6.2e-69 Smith-Waterman score: 1200; 100.0% identity (100.0% similar) in 184 aa overlap (1-184:1-184) 10 20 30 40 50 60 pF1KB8 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS 130 140 150 160 170 180 pF1KB8 CQLL :::: NP_056 CQLL >>NP_002875 (OMIM: 179520) ras-related protein Rap-1A pr (184 aa) initn: 1128 init1: 1128 opt: 1128 Z-score: 1278.0 bits: 243.1 E(85289): 1.9e-64 Smith-Waterman score: 1128; 95.1% identity (96.2% similar) in 184 aa overlap (1-184:1-184) 10 20 30 40 50 60 pF1KB8 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: NP_002 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: NP_002 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS :::::::::::::::::: :::::::::::::::::::::::::::::::: : ::.: NP_002 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS 130 140 150 160 170 180 pF1KB8 CQLL : :: NP_002 CLLL >>NP_001278825 (OMIM: 179520) ras-related protein Rap-1A (184 aa) initn: 1128 init1: 1128 opt: 1128 Z-score: 1278.0 bits: 243.1 E(85289): 1.9e-64 Smith-Waterman score: 1128; 95.1% identity (96.2% similar) in 184 aa overlap (1-184:1-184) 10 20 30 40 50 60 pF1KB8 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: NP_001 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: NP_001 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS :::::::::::::::::: :::::::::::::::::::::::::::::::: : ::.: NP_001 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS 130 140 150 160 170 180 pF1KB8 CQLL : :: NP_001 CLLL >>XP_016857452 (OMIM: 179520) PREDICTED: ras-related pro (184 aa) initn: 1128 init1: 1128 opt: 1128 Z-score: 1278.0 bits: 243.1 E(85289): 1.9e-64 Smith-Waterman score: 1128; 95.1% identity (96.2% similar) in 184 aa overlap (1-184:1-184) 10 20 30 40 50 60 pF1KB8 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: XP_016 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: XP_016 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS :::::::::::::::::: :::::::::::::::::::::::::::::::: : ::.: XP_016 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS 130 140 150 160 170 180 pF1KB8 CQLL : :: XP_016 CLLL >>XP_016857451 (OMIM: 179520) PREDICTED: ras-related pro (184 aa) initn: 1128 init1: 1128 opt: 1128 Z-score: 1278.0 bits: 243.1 E(85289): 1.9e-64 Smith-Waterman score: 1128; 95.1% identity (96.2% similar) in 184 aa overlap (1-184:1-184) 10 20 30 40 50 60 pF1KB8 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: XP_016 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: XP_016 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS :::::::::::::::::: :::::::::::::::::::::::::::::::: : ::.: XP_016 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS 130 140 150 160 170 180 pF1KB8 CQLL : :: XP_016 CLLL >>XP_016857453 (OMIM: 179520) PREDICTED: ras-related pro (184 aa) initn: 1128 init1: 1128 opt: 1128 Z-score: 1278.0 bits: 243.1 E(85289): 1.9e-64 Smith-Waterman score: 1128; 95.1% identity (96.2% similar) in 184 aa overlap (1-184:1-184) 10 20 30 40 50 60 pF1KB8 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: XP_016 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: XP_016 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS :::::::::::::::::: :::::::::::::::::::::::::::::::: : ::.: XP_016 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS 130 140 150 160 170 180 pF1KB8 CQLL : :: XP_016 CLLL >>NP_001010935 (OMIM: 179520) ras-related protein Rap-1A (184 aa) initn: 1128 init1: 1128 opt: 1128 Z-score: 1278.0 bits: 243.1 E(85289): 1.9e-64 Smith-Waterman score: 1128; 95.1% identity (96.2% similar) in 184 aa overlap (1-184:1-184) 10 20 30 40 50 60 pF1KB8 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: NP_001 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: NP_001 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS :::::::::::::::::: :::::::::::::::::::::::::::::::: : ::.: NP_001 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRKTPVEKKKPKKKS 130 140 150 160 170 180 pF1KB8 CQLL : :: NP_001 CLLL >>XP_016857450 (OMIM: 179520) PREDICTED: ras-related pro (195 aa) initn: 1024 init1: 1005 opt: 1005 Z-score: 1140.0 bits: 217.6 E(85289): 9.3e-57 Smith-Waterman score: 1005; 96.2% identity (98.1% similar) in 160 aa overlap (1-160:1-160) 10 20 30 40 50 60 pF1KB8 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: XP_016 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: XP_016 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS :::::::::::::::::: :::::::::::::::::. :. XP_016 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEVTYNCWAAQTSAFLVCFKLTARLL 130 140 150 160 170 180 pF1KB8 CQLL XP_016 RKNFYLLSNLDSIIL 190 >>XP_016857449 (OMIM: 179520) PREDICTED: ras-related pro (195 aa) initn: 1024 init1: 1005 opt: 1005 Z-score: 1140.0 bits: 217.6 E(85289): 9.3e-57 Smith-Waterman score: 1005; 96.2% identity (98.1% similar) in 160 aa overlap (1-160:1-160) 10 20 30 40 50 60 pF1KB8 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAG ::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::: XP_016 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDL ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: XP_016 TEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSS :::::::::::::::::: :::::::::::::::::. :. XP_016 EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEVTYNCWAAQTSAFLVCFKLTARLL 130 140 150 160 170 180 pF1KB8 CQLL XP_016 RKNFYLLSNLDSIIL 190 184 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 13:42:47 2016 done: Fri Nov 4 13:42:48 2016 Total Scan time: 4.200 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]