Result of FASTA (omim) for
pF1KB8625
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8625, 331 aa
1>>>pF1KB8625 331 - 331 aa - 331 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.8805+/-0.000392; mu= -0.3031+/- 0.025
mean_var=177.4726+/-35.168, 0's: 0 Z-trim(118.4): 19 B-trim: 0 in 0/55
Lambda= 0.096274
statistics sampled from 31362 (31380) to 31362 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.368), width: 16
Scan time: 7.130
The best scores are: opt bits E(85289)
NP_006591 (OMIM: 610325) nuclear migration protein ( 331) 2174 313.9 3.1e-85
XP_011538831 (OMIM: 610325) PREDICTED: nuclear mig ( 335) 1991 288.4 1.4e-77
XP_011538832 (OMIM: 610325) PREDICTED: nuclear mig ( 282) 1845 268.1 1.5e-71
XP_016855585 (OMIM: 610325) PREDICTED: nuclear mig ( 339) 1827 265.7 1e-70
XP_016855584 (OMIM: 610325) PREDICTED: nuclear mig ( 388) 1827 265.7 1.1e-70
XP_016855583 (OMIM: 610325) PREDICTED: nuclear mig ( 392) 1827 265.7 1.2e-70
XP_016867399 (OMIM: 610296) PREDICTED: nudC domain ( 192) 320 56.2 6.4e-08
XP_016867398 (OMIM: 610296) PREDICTED: nudC domain ( 192) 320 56.2 6.4e-08
>>NP_006591 (OMIM: 610325) nuclear migration protein nud (331 aa)
initn: 2174 init1: 2174 opt: 2174 Z-score: 1651.2 bits: 313.9 E(85289): 3.1e-85
Smith-Waterman score: 2174; 100.0% identity (100.0% similar) in 331 aa overlap (1-331:1-331)
10 20 30 40 50 60
pF1KB8 MGGEQEEERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFFIGGEEGMAEKLITQTFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MGGEQEEERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFFIGGEEGMAEKLITQTFS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 HHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 HHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEID
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 QKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGADLPNYRWTQTLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGADLPNYRWTQTLSE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LDLAVPFCVNFRLKGKDMVVDIQRRHLRVGLKGQPAIIDGELYNEVKVEESSWLIEDGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LDLAVPFCVNFRLKGKDMVVDIQRRHLRVGLKGQPAIIDGELYNEVKVEESSWLIEDGKV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VTVHLEKINKMEWWSRLVSSDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VTVHLEKINKMEWWSRLVSSDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMG
250 260 270 280 290 300
310 320 330
pF1KB8 LPTSDEQKKQEILKKFMDQHPEMDFSKAKFN
:::::::::::::::::::::::::::::::
NP_006 LPTSDEQKKQEILKKFMDQHPEMDFSKAKFN
310 320 330
>>XP_011538831 (OMIM: 610325) PREDICTED: nuclear migrati (335 aa)
initn: 1991 init1: 1991 opt: 1991 Z-score: 1513.8 bits: 288.4 E(85289): 1.4e-77
Smith-Waterman score: 1991; 100.0% identity (100.0% similar) in 304 aa overlap (28-331:32-335)
10 20 30 40 50
pF1KB8 MGGEQEEERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFFIGGEEGMAEKLITQ
::::::::::::::::::::::::::::::
XP_011 ISNYRNGSELVCFNSGVGCFLIGCDWAFTVLVNTFFSFLRRKTDFFIGGEEGMAEKLITQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 TFSHHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TFSHHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 EIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGADLPNYRWTQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIDQKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGADLPNYRWTQT
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 LSELDLAVPFCVNFRLKGKDMVVDIQRRHLRVGLKGQPAIIDGELYNEVKVEESSWLIED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSELDLAVPFCVNFRLKGKDMVVDIQRRHLRVGLKGQPAIIDGELYNEVKVEESSWLIED
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 GKVVTVHLEKINKMEWWSRLVSSDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKVVTVHLEKINKMEWWSRLVSSDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQK
250 260 270 280 290 300
300 310 320 330
pF1KB8 SMGLPTSDEQKKQEILKKFMDQHPEMDFSKAKFN
::::::::::::::::::::::::::::::::::
XP_011 SMGLPTSDEQKKQEILKKFMDQHPEMDFSKAKFN
310 320 330
>>XP_011538832 (OMIM: 610325) PREDICTED: nuclear migrati (282 aa)
initn: 1845 init1: 1845 opt: 1845 Z-score: 1405.4 bits: 268.1 E(85289): 1.5e-71
Smith-Waterman score: 1845; 100.0% identity (100.0% similar) in 282 aa overlap (50-331:1-282)
20 30 40 50 60 70
pF1KB8 QHEGGVQELVNTFFSFLRRKTDFFIGGEEGMAEKLITQTFSHHNQLAQKTRREKRARQEA
::::::::::::::::::::::::::::::
XP_011 MAEKLITQTFSHHNQLAQKTRREKRARQEA
10 20 30
80 90 100 110 120 130
pF1KB8 ERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAENHEAQLKNGSLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAENHEAQLKNGSLDS
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB8 PGKQDTEEDEEEDEKDKGKLKPNLGNGADLPNYRWTQTLSELDLAVPFCVNFRLKGKDMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGKQDTEEDEEEDEKDKGKLKPNLGNGADLPNYRWTQTLSELDLAVPFCVNFRLKGKDMV
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB8 VDIQRRHLRVGLKGQPAIIDGELYNEVKVEESSWLIEDGKVVTVHLEKINKMEWWSRLVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDIQRRHLRVGLKGQPAIIDGELYNEVKVEESSWLIEDGKVVTVHLEKINKMEWWSRLVS
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB8 SDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMGLPTSDEQKKQEILKKFMDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMGLPTSDEQKKQEILKKFMDQ
220 230 240 250 260 270
320 330
pF1KB8 HPEMDFSKAKFN
::::::::::::
XP_011 HPEMDFSKAKFN
280
>>XP_016855585 (OMIM: 610325) PREDICTED: nuclear migrati (339 aa)
initn: 1827 init1: 1827 opt: 1827 Z-score: 1390.6 bits: 265.7 E(85289): 1e-70
Smith-Waterman score: 1827; 100.0% identity (100.0% similar) in 279 aa overlap (53-331:61-339)
30 40 50 60 70 80
pF1KB8 GGVQELVNTFFSFLRRKTDFFIGGEEGMAEKLITQTFSHHNQLAQKTRREKRARQEAERR
::::::::::::::::::::::::::::::
XP_016 SYHENSMGETILVIQLPPPGTAFDMWELQFKLITQTFSHHNQLAQKTRREKRARQEAERR
40 50 60 70 80 90
90 100 110 120 130 140
pF1KB8 EKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAENHEAQLKNGSLDSPGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKKDAENHEAQLKNGSLDSPGK
100 110 120 130 140 150
150 160 170 180 190 200
pF1KB8 QDTEEDEEEDEKDKGKLKPNLGNGADLPNYRWTQTLSELDLAVPFCVNFRLKGKDMVVDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDTEEDEEEDEKDKGKLKPNLGNGADLPNYRWTQTLSELDLAVPFCVNFRLKGKDMVVDI
160 170 180 190 200 210
210 220 230 240 250 260
pF1KB8 QRRHLRVGLKGQPAIIDGELYNEVKVEESSWLIEDGKVVTVHLEKINKMEWWSRLVSSDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRRHLRVGLKGQPAIIDGELYNEVKVEESSWLIEDGKVVTVHLEKINKMEWWSRLVSSDP
220 230 240 250 260 270
270 280 290 300 310 320
pF1KB8 EINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMGLPTSDEQKKQEILKKFMDQHPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMGLPTSDEQKKQEILKKFMDQHPE
280 290 300 310 320 330
330
pF1KB8 MDFSKAKFN
:::::::::
XP_016 MDFSKAKFN
>>XP_016855584 (OMIM: 610325) PREDICTED: nuclear migrati (388 aa)
initn: 1827 init1: 1827 opt: 1827 Z-score: 1389.7 bits: 265.7 E(85289): 1.1e-70
Smith-Waterman score: 1880; 84.3% identity (84.3% similar) in 363 aa overlap (26-331:26-388)
10 20 30 40 50
pF1KB8 MGGEQEEERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFFIGGEEGMAEK-------
::::::::::::::::::::::::::::
XP_016 MGGEQEEERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFFIGGEEGMAEKIGRRENE
10 20 30 40 50 60
60
pF1KB8 --------------------------------------------------LITQTFSHHN
::::::::::
XP_016 CQQKKCQTLIKPSDLVRTHSYHENSMGETILVIQLPPPGTAFDMWELQFKLITQTFSHHN
70 80 90 100 110 120
70 80 90 100 110 120
pF1KB8 QLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEIDQKK
130 140 150 160 170 180
130 140 150 160 170 180
pF1KB8 DAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGADLPNYRWTQTLSELDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGADLPNYRWTQTLSELDL
190 200 210 220 230 240
190 200 210 220 230 240
pF1KB8 AVPFCVNFRLKGKDMVVDIQRRHLRVGLKGQPAIIDGELYNEVKVEESSWLIEDGKVVTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVPFCVNFRLKGKDMVVDIQRRHLRVGLKGQPAIIDGELYNEVKVEESSWLIEDGKVVTV
250 260 270 280 290 300
250 260 270 280 290 300
pF1KB8 HLEKINKMEWWSRLVSSDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMGLPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLEKINKMEWWSRLVSSDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMGLPT
310 320 330 340 350 360
310 320 330
pF1KB8 SDEQKKQEILKKFMDQHPEMDFSKAKFN
::::::::::::::::::::::::::::
XP_016 SDEQKKQEILKKFMDQHPEMDFSKAKFN
370 380
>>XP_016855583 (OMIM: 610325) PREDICTED: nuclear migrati (392 aa)
initn: 1827 init1: 1827 opt: 1827 Z-score: 1389.6 bits: 265.7 E(85289): 1.2e-70
Smith-Waterman score: 1867; 84.2% identity (84.2% similar) in 361 aa overlap (28-331:32-392)
10 20 30 40 50
pF1KB8 MGGEQEEERFDGMLLAMAQQHEGGVQELVNTFFSFLRRKTDFFIGGEEGMAEK----
::::::::::::::::::::::::::
XP_016 ISNYRNGSELVCFNSGVGCFLIGCDWAFTVLVNTFFSFLRRKTDFFIGGEEGMAEKIGRR
10 20 30 40 50 60
60
pF1KB8 -----------------------------------------------------LITQTFS
:::::::
XP_016 ENECQQKKCQTLIKPSDLVRTHSYHENSMGETILVIQLPPPGTAFDMWELQFKLITQTFS
70 80 90 100 110 120
70 80 90 100 110 120
pF1KB8 HHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HHNQLAQKTRREKRARQEAERREKAERAARLAKEAKSETSGPQIKELTDEEAERLQLEID
130 140 150 160 170 180
130 140 150 160 170 180
pF1KB8 QKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGADLPNYRWTQTLSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKKDAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGADLPNYRWTQTLSE
190 200 210 220 230 240
190 200 210 220 230 240
pF1KB8 LDLAVPFCVNFRLKGKDMVVDIQRRHLRVGLKGQPAIIDGELYNEVKVEESSWLIEDGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDLAVPFCVNFRLKGKDMVVDIQRRHLRVGLKGQPAIIDGELYNEVKVEESSWLIEDGKV
250 260 270 280 290 300
250 260 270 280 290 300
pF1KB8 VTVHLEKINKMEWWSRLVSSDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTVHLEKINKMEWWSRLVSSDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMG
310 320 330 340 350 360
310 320 330
pF1KB8 LPTSDEQKKQEILKKFMDQHPEMDFSKAKFN
:::::::::::::::::::::::::::::::
XP_016 LPTSDEQKKQEILKKFMDQHPEMDFSKAKFN
370 380 390
>>XP_016867399 (OMIM: 610296) PREDICTED: nudC domain-con (192 aa)
initn: 163 init1: 73 opt: 320 Z-score: 263.2 bits: 56.2 E(85289): 6.4e-08
Smith-Waterman score: 320; 30.8% identity (64.3% similar) in 185 aa overlap (154-331:3-184)
130 140 150 160 170 180
pF1KB8 DAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGADLPNYRWTQTLSELDL
... . .:. ::: :: :.: ..:..
XP_016 MIQEQFQKNPDSYNGAVRENYTWSQDYTDLEV
10 20 30
190 200 210 220 230 240
pF1KB8 AVPFCVNFRLKGKDMVVDIQRRHLRVGL---KGQPAIIDGELYNEVKVEESSWLIEDGKV
:: . .:::.. : .. .::.. .:. ....:.: .....: : : .: ::
XP_016 RVPVPKHV-VKGKQVSVALSSSSIRVAMLEENGERVLMEGKLTHKINTESSLWSLEPGKC
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB8 VTVHLEKINKMEWWSRLVSSDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMG
: :.: :.... ::. .. .. :. ::: : : .. .: : ....... .: .:: .:
XP_016 VLVNLSKVGEY-WWNAILEGEEPIDIDKINKERS-MATVDEEEQAVLDRLTFDYHQKLQG
100 110 120 130 140
310 320 330
pF1KB8 LPTSDEQKKQEILKKFMDQHPE----MDFSKAKFN
: : : : .:.::: : . . :. : ::
XP_016 KPQSHELKVHEMLKKGWDAEGSPFRGQRFDPAMFNISPGAVQF
150 160 170 180 190
>>XP_016867398 (OMIM: 610296) PREDICTED: nudC domain-con (192 aa)
initn: 163 init1: 73 opt: 320 Z-score: 263.2 bits: 56.2 E(85289): 6.4e-08
Smith-Waterman score: 320; 30.8% identity (64.3% similar) in 185 aa overlap (154-331:3-184)
130 140 150 160 170 180
pF1KB8 DAENHEAQLKNGSLDSPGKQDTEEDEEEDEKDKGKLKPNLGNGADLPNYRWTQTLSELDL
... . .:. ::: :: :.: ..:..
XP_016 MIQEQFQKNPDSYNGAVRENYTWSQDYTDLEV
10 20 30
190 200 210 220 230 240
pF1KB8 AVPFCVNFRLKGKDMVVDIQRRHLRVGL---KGQPAIIDGELYNEVKVEESSWLIEDGKV
:: . .:::.. : .. .::.. .:. ....:.: .....: : : .: ::
XP_016 RVPVPKHV-VKGKQVSVALSSSSIRVAMLEENGERVLMEGKLTHKINTESSLWSLEPGKC
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB8 VTVHLEKINKMEWWSRLVSSDPEINTKKINPENSKLSDLDSETRSMVEKMMYDQRQKSMG
: :.: :.... ::. .. .. :. ::: : : .. .: : ....... .: .:: .:
XP_016 VLVNLSKVGEY-WWNAILEGEEPIDIDKINKERS-MATVDEEEQAVLDRLTFDYHQKLQG
100 110 120 130 140
310 320 330
pF1KB8 LPTSDEQKKQEILKKFMDQHPE----MDFSKAKFN
: : : : .:.::: : . . :. : ::
XP_016 KPQSHELKVHEMLKKGWDAEGSPFRGQRFDPAMFNISPGAVQF
150 160 170 180 190
331 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 13:53:52 2016 done: Fri Nov 4 13:53:53 2016
Total Scan time: 7.130 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]