FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8629, 531 aa 1>>>pF1KB8629 531 - 531 aa - 531 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4511+/-0.000486; mu= 17.0267+/- 0.030 mean_var=70.8283+/-14.641, 0's: 0 Z-trim(109.2): 277 B-trim: 958 in 2/54 Lambda= 0.152395 statistics sampled from 17013 (17322) to 17013 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.553), E-opt: 0.2 (0.203), width: 16 Scan time: 8.680 The best scores are: opt bits E(85289) XP_011533436 (OMIM: 103780,607867) PREDICTED: RCC1 ( 531) 3617 805.2 0 NP_060661 (OMIM: 103780,607867) RCC1 and BTB domai ( 531) 3617 805.2 0 XP_005266498 (OMIM: 103780,607867) PREDICTED: RCC1 ( 531) 3617 805.2 0 XP_011533435 (OMIM: 103780,607867) PREDICTED: RCC1 ( 531) 3617 805.2 0 XP_011533437 (OMIM: 103780,607867) PREDICTED: RCC1 ( 402) 2632 588.6 1.2e-167 NP_001273760 (OMIM: 603524) RCC1 and BTB domain-co ( 527) 2619 585.8 1.1e-166 XP_005266301 (OMIM: 603524) PREDICTED: RCC1 and BT ( 527) 2619 585.8 1.1e-166 XP_006719822 (OMIM: 603524) PREDICTED: RCC1 and BT ( 551) 2619 585.8 1.1e-166 NP_001259 (OMIM: 603524) RCC1 and BTB domain-conta ( 551) 2619 585.8 1.1e-166 XP_005266299 (OMIM: 603524) PREDICTED: RCC1 and BT ( 551) 2619 585.8 1.1e-166 XP_016875862 (OMIM: 603524) PREDICTED: RCC1 and BT ( 555) 2619 585.8 1.1e-166 XP_011533196 (OMIM: 603524) PREDICTED: RCC1 and BT ( 556) 2619 585.8 1.1e-166 XP_016875860 (OMIM: 603524) PREDICTED: RCC1 and BT ( 556) 2619 585.8 1.1e-166 XP_016875861 (OMIM: 603524) PREDICTED: RCC1 and BT ( 556) 2619 585.8 1.1e-166 NP_001273759 (OMIM: 603524) RCC1 and BTB domain-co ( 556) 2619 585.8 1.1e-166 XP_016875859 (OMIM: 603524) PREDICTED: RCC1 and BT ( 561) 2619 585.8 1.2e-166 XP_016875858 (OMIM: 603524) PREDICTED: RCC1 and BT ( 561) 2619 585.8 1.2e-166 XP_011533438 (OMIM: 103780,607867) PREDICTED: RCC1 ( 288) 1929 433.9 3.1e-121 XP_016875863 (OMIM: 603524) PREDICTED: RCC1 and BT ( 340) 1350 306.7 7.4e-83 XP_016875864 (OMIM: 603524) PREDICTED: RCC1 and BT ( 340) 1350 306.7 7.4e-83 XP_016875865 (OMIM: 603524) PREDICTED: RCC1 and BT ( 324) 1348 306.2 9.6e-83 XP_016875867 (OMIM: 603524) PREDICTED: RCC1 and BT ( 277) 1276 290.4 4.9e-78 XP_016875868 (OMIM: 603524) PREDICTED: RCC1 and BT ( 277) 1276 290.4 4.9e-78 XP_011533197 (OMIM: 603524) PREDICTED: RCC1 and BT ( 277) 1276 290.4 4.9e-78 NP_001273761 (OMIM: 603524) RCC1 and BTB domain-co ( 277) 1276 290.4 4.9e-78 XP_016875866 (OMIM: 603524) PREDICTED: RCC1 and BT ( 285) 1105 252.8 1e-66 NP_001305434 (OMIM: 605200) probable E3 ubiquitin- ( 368) 525 125.3 3.2e-28 XP_005263389 (OMIM: 605200) PREDICTED: probable E3 ( 896) 526 125.7 5.7e-28 XP_005263388 (OMIM: 605200) PREDICTED: probable E3 ( 903) 526 125.7 5.7e-28 XP_005263387 (OMIM: 605200) PREDICTED: probable E3 ( 993) 526 125.8 6.2e-28 XP_005263386 (OMIM: 605200) PREDICTED: probable E3 (1042) 526 125.8 6.4e-28 XP_016864295 (OMIM: 605200) PREDICTED: probable E3 (1042) 526 125.8 6.4e-28 XP_005263384 (OMIM: 605200) PREDICTED: probable E3 (1050) 526 125.8 6.5e-28 NP_055421 (OMIM: 605200) probable E3 ubiquitin-pro (1050) 526 125.8 6.5e-28 XP_016871530 (OMIM: 609248) PREDICTED: probable E3 ( 936) 521 124.7 1.3e-27 NP_001265114 (OMIM: 609248) probable E3 ubiquitin- ( 979) 521 124.7 1.3e-27 NP_056416 (OMIM: 609248) probable E3 ubiquitin-pro (1049) 521 124.7 1.4e-27 NP_071362 (OMIM: 609248) probable E3 ubiquitin-pro (1057) 521 124.7 1.4e-27 NP_003913 (OMIM: 605109,617011) probable E3 ubiqui (4861) 495 119.3 2.6e-25 XP_016878194 (OMIM: 605109,617011) PREDICTED: prob (4883) 495 119.3 2.6e-25 XP_016878193 (OMIM: 605109,617011) PREDICTED: prob (4885) 495 119.3 2.6e-25 XP_016878192 (OMIM: 605109,617011) PREDICTED: prob (4891) 495 119.3 2.6e-25 XP_016878190 (OMIM: 605109,617011) PREDICTED: prob (4892) 495 119.3 2.6e-25 XP_016878191 (OMIM: 605109,617011) PREDICTED: prob (4892) 495 119.3 2.6e-25 XP_016878189 (OMIM: 605109,617011) PREDICTED: prob (4897) 495 119.3 2.6e-25 XP_016878188 (OMIM: 605109,617011) PREDICTED: prob (4909) 495 119.3 2.6e-25 XP_011537898 (OMIM: 609248) PREDICTED: probable E3 ( 987) 481 115.9 5.9e-25 XP_016878187 (OMIM: 176270,227220,605837,615516) P (2556) 475 114.8 3.2e-24 XP_016878186 (OMIM: 176270,227220,605837,615516) P (2556) 475 114.8 3.2e-24 XP_011520435 (OMIM: 176270,227220,605837,615516) P (3749) 475 114.9 4.4e-24 >>XP_011533436 (OMIM: 103780,607867) PREDICTED: RCC1 and (531 aa) initn: 3617 init1: 3617 opt: 3617 Z-score: 4299.3 bits: 805.2 E(85289): 0 Smith-Waterman score: 3617; 100.0% identity (100.0% similar) in 531 aa overlap (1-531:1-531) 10 20 30 40 50 60 pF1KB8 MVDVGKWPIFTLLSPQEIASIRKACVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVDVGKWPIFTLLSPQEIASIRKACVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 STLVPKKLEGLCGKKIKSLSYGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STLVPKKLEGLCGKKIKSLSYGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 KRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 GYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIMVEKERVVEIAACHSAHTSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIMVEKERVVEIAACHSAHTSAA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 KTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACFATPAVSWRLLSVEHEDFLTVAESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACFATPAVSWRLLSVEHEDFLTVAESL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 KKEFDSPETADLKFRIDGKYIHVHKAVLKIRCEHFRSMFQSYWNEDMKEVIEIDQFSYPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKEFDSPETADLKFRIDGKYIHVHKAVLKIRCEHFRSMFQSYWNEDMKEVIEIDQFSYPV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 YRAFLQYLYTDTVDLPPEDAIGLLDLATSYCENRLKKLCQHIIKRGITVENAFSLFSAAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YRAFLQYLYTDTVDLPPEDAIGLLDLATSYCENRLKKLCQHIIKRGITVENAFSLFSAAV 430 440 450 460 470 480 490 500 510 520 530 pF1KB8 RYDAEDLEEFCFKFCINHLTEVTQTAAFWQMDGPLLKEFIAKASKCGAFKN ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RYDAEDLEEFCFKFCINHLTEVTQTAAFWQMDGPLLKEFIAKASKCGAFKN 490 500 510 520 530 >>NP_060661 (OMIM: 103780,607867) RCC1 and BTB domain-co (531 aa) initn: 3617 init1: 3617 opt: 3617 Z-score: 4299.3 bits: 805.2 E(85289): 0 Smith-Waterman score: 3617; 100.0% identity (100.0% similar) in 531 aa overlap (1-531:1-531) 10 20 30 40 50 60 pF1KB8 MVDVGKWPIFTLLSPQEIASIRKACVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MVDVGKWPIFTLLSPQEIASIRKACVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 STLVPKKLEGLCGKKIKSLSYGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 STLVPKKLEGLCGKKIKSLSYGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 VCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 KRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 KRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 GYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIMVEKERVVEIAACHSAHTSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 GYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIMVEKERVVEIAACHSAHTSAA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 KTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACFATPAVSWRLLSVEHEDFLTVAESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 KTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACFATPAVSWRLLSVEHEDFLTVAESL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 KKEFDSPETADLKFRIDGKYIHVHKAVLKIRCEHFRSMFQSYWNEDMKEVIEIDQFSYPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 KKEFDSPETADLKFRIDGKYIHVHKAVLKIRCEHFRSMFQSYWNEDMKEVIEIDQFSYPV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 YRAFLQYLYTDTVDLPPEDAIGLLDLATSYCENRLKKLCQHIIKRGITVENAFSLFSAAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 YRAFLQYLYTDTVDLPPEDAIGLLDLATSYCENRLKKLCQHIIKRGITVENAFSLFSAAV 430 440 450 460 470 480 490 500 510 520 530 pF1KB8 RYDAEDLEEFCFKFCINHLTEVTQTAAFWQMDGPLLKEFIAKASKCGAFKN ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 RYDAEDLEEFCFKFCINHLTEVTQTAAFWQMDGPLLKEFIAKASKCGAFKN 490 500 510 520 530 >>XP_005266498 (OMIM: 103780,607867) PREDICTED: RCC1 and (531 aa) initn: 3617 init1: 3617 opt: 3617 Z-score: 4299.3 bits: 805.2 E(85289): 0 Smith-Waterman score: 3617; 100.0% identity (100.0% similar) in 531 aa overlap (1-531:1-531) 10 20 30 40 50 60 pF1KB8 MVDVGKWPIFTLLSPQEIASIRKACVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MVDVGKWPIFTLLSPQEIASIRKACVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 STLVPKKLEGLCGKKIKSLSYGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 STLVPKKLEGLCGKKIKSLSYGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 KRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 GYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIMVEKERVVEIAACHSAHTSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIMVEKERVVEIAACHSAHTSAA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 KTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACFATPAVSWRLLSVEHEDFLTVAESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACFATPAVSWRLLSVEHEDFLTVAESL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 KKEFDSPETADLKFRIDGKYIHVHKAVLKIRCEHFRSMFQSYWNEDMKEVIEIDQFSYPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KKEFDSPETADLKFRIDGKYIHVHKAVLKIRCEHFRSMFQSYWNEDMKEVIEIDQFSYPV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 YRAFLQYLYTDTVDLPPEDAIGLLDLATSYCENRLKKLCQHIIKRGITVENAFSLFSAAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YRAFLQYLYTDTVDLPPEDAIGLLDLATSYCENRLKKLCQHIIKRGITVENAFSLFSAAV 430 440 450 460 470 480 490 500 510 520 530 pF1KB8 RYDAEDLEEFCFKFCINHLTEVTQTAAFWQMDGPLLKEFIAKASKCGAFKN ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RYDAEDLEEFCFKFCINHLTEVTQTAAFWQMDGPLLKEFIAKASKCGAFKN 490 500 510 520 530 >>XP_011533435 (OMIM: 103780,607867) PREDICTED: RCC1 and (531 aa) initn: 3617 init1: 3617 opt: 3617 Z-score: 4299.3 bits: 805.2 E(85289): 0 Smith-Waterman score: 3617; 100.0% identity (100.0% similar) in 531 aa overlap (1-531:1-531) 10 20 30 40 50 60 pF1KB8 MVDVGKWPIFTLLSPQEIASIRKACVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVDVGKWPIFTLLSPQEIASIRKACVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 STLVPKKLEGLCGKKIKSLSYGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 STLVPKKLEGLCGKKIKSLSYGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 KRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 GYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIMVEKERVVEIAACHSAHTSAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIMVEKERVVEIAACHSAHTSAA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 KTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACFATPAVSWRLLSVEHEDFLTVAESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACFATPAVSWRLLSVEHEDFLTVAESL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 KKEFDSPETADLKFRIDGKYIHVHKAVLKIRCEHFRSMFQSYWNEDMKEVIEIDQFSYPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KKEFDSPETADLKFRIDGKYIHVHKAVLKIRCEHFRSMFQSYWNEDMKEVIEIDQFSYPV 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB8 YRAFLQYLYTDTVDLPPEDAIGLLDLATSYCENRLKKLCQHIIKRGITVENAFSLFSAAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YRAFLQYLYTDTVDLPPEDAIGLLDLATSYCENRLKKLCQHIIKRGITVENAFSLFSAAV 430 440 450 460 470 480 490 500 510 520 530 pF1KB8 RYDAEDLEEFCFKFCINHLTEVTQTAAFWQMDGPLLKEFIAKASKCGAFKN ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RYDAEDLEEFCFKFCINHLTEVTQTAAFWQMDGPLLKEFIAKASKCGAFKN 490 500 510 520 530 >>XP_011533437 (OMIM: 103780,607867) PREDICTED: RCC1 and (402 aa) initn: 2632 init1: 2632 opt: 2632 Z-score: 3130.8 bits: 588.6 E(85289): 1.2e-167 Smith-Waterman score: 2632; 99.0% identity (99.5% similar) in 388 aa overlap (144-531:15-402) 120 130 140 150 160 170 pF1KB8 QGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRK .: .::::::::::::::::::::::::: XP_011 MESSGLHVATASSGSAGHQVFAWGYNNCGQVGSGSTANQPTPRK 10 20 30 40 180 190 200 210 220 230 pF1KB8 VTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSV 50 60 70 80 90 100 240 250 260 270 280 290 pF1KB8 CVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIMVEKERVVEIAACH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIMVEKERVVEIAACH 110 120 130 140 150 160 300 310 320 330 340 350 pF1KB8 SAHTSAAKTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACFATPAVSWRLLSVEHEDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAHTSAAKTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACFATPAVSWRLLSVEHEDF 170 180 190 200 210 220 360 370 380 390 400 410 pF1KB8 LTVAESLKKEFDSPETADLKFRIDGKYIHVHKAVLKIRCEHFRSMFQSYWNEDMKEVIEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTVAESLKKEFDSPETADLKFRIDGKYIHVHKAVLKIRCEHFRSMFQSYWNEDMKEVIEI 230 240 250 260 270 280 420 430 440 450 460 470 pF1KB8 DQFSYPVYRAFLQYLYTDTVDLPPEDAIGLLDLATSYCENRLKKLCQHIIKRGITVENAF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQFSYPVYRAFLQYLYTDTVDLPPEDAIGLLDLATSYCENRLKKLCQHIIKRGITVENAF 290 300 310 320 330 340 480 490 500 510 520 530 pF1KB8 SLFSAAVRYDAEDLEEFCFKFCINHLTEVTQTAAFWQMDGPLLKEFIAKASKCGAFKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLFSAAVRYDAEDLEEFCFKFCINHLTEVTQTAAFWQMDGPLLKEFIAKASKCGAFKN 350 360 370 380 390 400 >>NP_001273760 (OMIM: 603524) RCC1 and BTB domain-contai (527 aa) initn: 2037 init1: 2037 opt: 2619 Z-score: 3113.6 bits: 585.8 E(85289): 1.1e-166 Smith-Waterman score: 2619; 70.4% identity (89.3% similar) in 531 aa overlap (1-531:1-527) 10 20 30 40 50 60 pF1KB8 MVDVGKWPIFTLLSPQEIASIRKACVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQ :.::::::::.: : .:. ::.:::::....:.::.: :::.::.: : .::: :: : NP_001 MLDVGKWPIFSLCSEEELQLIRQACVFGSAGNEVLYTTVNDEIFVLGTNCCGCLGLGDVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 STLVPKKLEGLCGKKIKSLSYGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQ ::. :..:..: :::: ::::::::..:.: .: :..::::.::::::::::.:..: . NP_001 STIEPRRLDSLNGKKIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNGTTNHGLVPCH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHI . ::: :::.::::::.::..:..::::::::::: ::::::::.::: ::.::.::. NP_001 ISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 KRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVC : :: ::::: :::.:.:::: :::::::::::::.::: :: :::::... :....: NP_001 KVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVAC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 GYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIMVEKERVVEIAACHSAHTSAA ::::::.::::: .::::::.:::::::::.: :. . :::.:..:::::::.::::: NP_001 GYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKDRIIEIAACHSTHTSAA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 KTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACFATPAVSWRLLSVEHEDFLTVAESL :::::::::::::::::::::::::::::::::::::::::.::::::: .: ::::::: NP_001 KTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACFATPAVTWRLLSVEPDDHLTVAESL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 KKEFDSPETADLKFRIDGKYIHVHKAVLKIRCEHFRSMFQSYWNEDMKEVIEIDQFSYPV :.:::.:.:::::: .:::::..::..:::::::::: ... ::: ...:...::::: NP_001 KREFDNPDTADLKFLVDGKYIYAHKVLLKIRCEHFRSSLED--NED--DIVEMSEFSYPV 370 380 390 400 410 430 440 450 460 470 480 pF1KB8 YRAFLQYLYTDTVDLPPEDAIGLLDLATSYCENRLKKLCQHIIKRGITVENAFSLFSAAV :::::.:::::...: ::.:.::::::: : :::::::::. ::.:: :::..:.:::: NP_001 YRAFLEYLYTDSISLSPEEAVGLLDLATFYRENRLKKLCQQTIKQGICEENAIALLSAAV 420 430 440 450 460 470 490 500 510 520 530 pF1KB8 RYDAEDLEEFCFKFCINHLTEVTQTAAFWQMDGPLLKEFIAKASKCGAFKN .:::.:::::::.::::::: ::::..: .:: :::.::.:::. ::::: NP_001 KYDAQDLEEFCFRFCINHLTVVTQTSGFAEMDHDLLKNFISKASRVGAFKN 480 490 500 510 520 >>XP_005266301 (OMIM: 603524) PREDICTED: RCC1 and BTB do (527 aa) initn: 2037 init1: 2037 opt: 2619 Z-score: 3113.6 bits: 585.8 E(85289): 1.1e-166 Smith-Waterman score: 2619; 70.4% identity (89.3% similar) in 531 aa overlap (1-531:1-527) 10 20 30 40 50 60 pF1KB8 MVDVGKWPIFTLLSPQEIASIRKACVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQ :.::::::::.: : .:. ::.:::::....:.::.: :::.::.: : .::: :: : XP_005 MLDVGKWPIFSLCSEEELQLIRQACVFGSAGNEVLYTTVNDEIFVLGTNCCGCLGLGDVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 STLVPKKLEGLCGKKIKSLSYGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQ ::. :..:..: :::: ::::::::..:.: .: :..::::.::::::::::.:..: . XP_005 STIEPRRLDSLNGKKIACLSYGSGPHIVLATTEGEVFTWGHNAYSQLGNGTTNHGLVPCH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHI . ::: :::.::::::.::..:..::::::::::: ::::::::.::: ::.::.::. XP_005 ISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNNSGQVGSGSTVNQPIPRRVTGCLQN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 KRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVC : :: ::::: :::.:.:::: :::::::::::::.::: :: :::::... :....: XP_005 KVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVAC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 GYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIMVEKERVVEIAACHSAHTSAA ::::::.::::: .::::::.:::::::::.: :. . :::.:..:::::::.::::: XP_005 GYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKDRIIEIAACHSTHTSAA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 KTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACFATPAVSWRLLSVEHEDFLTVAESL :::::::::::::::::::::::::::::::::::::::::.::::::: .: ::::::: XP_005 KTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACFATPAVTWRLLSVEPDDHLTVAESL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB8 KKEFDSPETADLKFRIDGKYIHVHKAVLKIRCEHFRSMFQSYWNEDMKEVIEIDQFSYPV :.:::.:.:::::: .:::::..::..:::::::::: ... ::: ...:...::::: XP_005 KREFDNPDTADLKFLVDGKYIYAHKVLLKIRCEHFRSSLED--NED--DIVEMSEFSYPV 370 380 390 400 410 430 440 450 460 470 480 pF1KB8 YRAFLQYLYTDTVDLPPEDAIGLLDLATSYCENRLKKLCQHIIKRGITVENAFSLFSAAV :::::.:::::...: ::.:.::::::: : :::::::::. ::.:: :::..:.:::: XP_005 YRAFLEYLYTDSISLSPEEAVGLLDLATFYRENRLKKLCQQTIKQGICEENAIALLSAAV 420 430 440 450 460 470 490 500 510 520 530 pF1KB8 RYDAEDLEEFCFKFCINHLTEVTQTAAFWQMDGPLLKEFIAKASKCGAFKN .:::.:::::::.::::::: ::::..: .:: :::.::.:::. ::::: XP_005 KYDAQDLEEFCFRFCINHLTVVTQTSGFAEMDHDLLKNFISKASRVGAFKN 480 490 500 510 520 >>XP_006719822 (OMIM: 603524) PREDICTED: RCC1 and BTB do (551 aa) initn: 2037 init1: 2037 opt: 2619 Z-score: 3113.3 bits: 585.8 E(85289): 1.1e-166 Smith-Waterman score: 2619; 70.4% identity (89.3% similar) in 531 aa overlap (1-531:25-551) 10 20 30 pF1KB8 MVDVGKWPIFTLLSPQEIASIRKACVFGTSASEALY :.::::::::.: : .:. ::.:::::....:.:: XP_006 MEEELPLFSGDSGKPVQATLSSLKMLDVGKWPIFSLCSEEELQLIRQACVFGSAGNEVLY 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 VTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSYGSGPHVLLSTEDGVV .: :::.::.: : .::: :: :::. :..:..: :::: ::::::::..:.: .: : XP_006 TTVNDEIFVLGTNCCGCLGLGDVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTEGEV 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB8 YAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNN ..::::.::::::::::.:..: .. ::: :::.::::::.::..:..::::::::::: XP_006 FTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNN 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB8 CGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLG ::::::::.::: ::.::.::. : :: ::::: :::.:.:::: :::::::::::: XP_006 SGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLG 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB8 NNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSP :.::: :: :::::... :....:::::::.::::: .::::::.:::::::::.: : XP_006 NSGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYP 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB8 AHIMVEKERVVEIAACHSAHTSAAKTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACF . . :::.:..:::::::.::::::::::::::::::::::::::::::::::::::::: XP_006 TPVTVEKDRIIEIAACHSTHTSAAKTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACF 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB8 ATPAVSWRLLSVEHEDFLTVAESLKKEFDSPETADLKFRIDGKYIHVHKAVLKIRCEHFR :::::.::::::: .: ::::::::.:::.:.:::::: .:::::..::..::::::::: XP_006 ATPAVTWRLLSVEPDDHLTVAESLKREFDNPDTADLKFLVDGKYIYAHKVLLKIRCEHFR 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB8 SMFQSYWNEDMKEVIEIDQFSYPVYRAFLQYLYTDTVDLPPEDAIGLLDLATSYCENRLK : ... ::: ...:...::::::::::.:::::...: ::.:.::::::: : ::::: XP_006 SSLED--NED--DIVEMSEFSYPVYRAFLEYLYTDSISLSPEEAVGLLDLATFYRENRLK 430 440 450 460 470 460 470 480 490 500 510 pF1KB8 KLCQHIIKRGITVENAFSLFSAAVRYDAEDLEEFCFKFCINHLTEVTQTAAFWQMDGPLL ::::. ::.:: :::..:.::::.:::.:::::::.::::::: ::::..: .:: :: XP_006 KLCQQTIKQGICEENAIALLSAAVKYDAQDLEEFCFRFCINHLTVVTQTSGFAEMDHDLL 480 490 500 510 520 530 520 530 pF1KB8 KEFIAKASKCGAFKN :.::.:::. ::::: XP_006 KNFISKASRVGAFKN 540 550 >>NP_001259 (OMIM: 603524) RCC1 and BTB domain-containin (551 aa) initn: 2037 init1: 2037 opt: 2619 Z-score: 3113.3 bits: 585.8 E(85289): 1.1e-166 Smith-Waterman score: 2619; 70.4% identity (89.3% similar) in 531 aa overlap (1-531:25-551) 10 20 30 pF1KB8 MVDVGKWPIFTLLSPQEIASIRKACVFGTSASEALY :.::::::::.: : .:. ::.:::::....:.:: NP_001 MEEELPLFSGDSGKPVQATLSSLKMLDVGKWPIFSLCSEEELQLIRQACVFGSAGNEVLY 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 VTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSYGSGPHVLLSTEDGVV .: :::.::.: : .::: :: :::. :..:..: :::: ::::::::..:.: .: : NP_001 TTVNDEIFVLGTNCCGCLGLGDVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTEGEV 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB8 YAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNN ..::::.::::::::::.:..: .. ::: :::.::::::.::..:..::::::::::: NP_001 FTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNN 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB8 CGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLG ::::::::.::: ::.::.::. : :: ::::: :::.:.:::: :::::::::::: NP_001 SGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLG 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB8 NNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSP :.::: :: :::::... :....:::::::.::::: .::::::.:::::::::.: : NP_001 NSGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYP 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB8 AHIMVEKERVVEIAACHSAHTSAAKTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACF . . :::.:..:::::::.::::::::::::::::::::::::::::::::::::::::: NP_001 TPVTVEKDRIIEIAACHSTHTSAAKTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACF 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB8 ATPAVSWRLLSVEHEDFLTVAESLKKEFDSPETADLKFRIDGKYIHVHKAVLKIRCEHFR :::::.::::::: .: ::::::::.:::.:.:::::: .:::::..::..::::::::: NP_001 ATPAVTWRLLSVEPDDHLTVAESLKREFDNPDTADLKFLVDGKYIYAHKVLLKIRCEHFR 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB8 SMFQSYWNEDMKEVIEIDQFSYPVYRAFLQYLYTDTVDLPPEDAIGLLDLATSYCENRLK : ... ::: ...:...::::::::::.:::::...: ::.:.::::::: : ::::: NP_001 SSLED--NED--DIVEMSEFSYPVYRAFLEYLYTDSISLSPEEAVGLLDLATFYRENRLK 430 440 450 460 470 460 470 480 490 500 510 pF1KB8 KLCQHIIKRGITVENAFSLFSAAVRYDAEDLEEFCFKFCINHLTEVTQTAAFWQMDGPLL ::::. ::.:: :::..:.::::.:::.:::::::.::::::: ::::..: .:: :: NP_001 KLCQQTIKQGICEENAIALLSAAVKYDAQDLEEFCFRFCINHLTVVTQTSGFAEMDHDLL 480 490 500 510 520 530 520 530 pF1KB8 KEFIAKASKCGAFKN :.::.:::. ::::: NP_001 KNFISKASRVGAFKN 540 550 >>XP_005266299 (OMIM: 603524) PREDICTED: RCC1 and BTB do (551 aa) initn: 2037 init1: 2037 opt: 2619 Z-score: 3113.3 bits: 585.8 E(85289): 1.1e-166 Smith-Waterman score: 2619; 70.4% identity (89.3% similar) in 531 aa overlap (1-531:25-551) 10 20 30 pF1KB8 MVDVGKWPIFTLLSPQEIASIRKACVFGTSASEALY :.::::::::.: : .:. ::.:::::....:.:: XP_005 MEEELPLFSGDSGKPVQATLSSLKMLDVGKWPIFSLCSEEELQLIRQACVFGSAGNEVLY 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB8 VTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSYGSGPHVLLSTEDGVV .: :::.::.: : .::: :: :::. :..:..: :::: ::::::::..:.: .: : XP_005 TTVNDEIFVLGTNCCGCLGLGDVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTEGEV 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB8 YAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNN ..::::.::::::::::.:..: .. ::: :::.::::::.::..:..::::::::::: XP_005 FTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAWGYNN 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB8 CGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLG ::::::::.::: ::.::.::. : :: ::::: :::.:.:::: :::::::::::: XP_005 SGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNGQLGLG 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB8 NNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSP :.::: :: :::::... :....:::::::.::::: .::::::.:::::::::.: : XP_005 NSGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQLGTGNKSNQSYP 250 260 270 280 290 300 280 290 300 310 320 330 pF1KB8 AHIMVEKERVVEIAACHSAHTSAAKTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACF . . :::.:..:::::::.::::::::::::::::::::::::::::::::::::::::: XP_005 TPVTVEKDRIIEIAACHSTHTSAAKTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACF 310 320 330 340 350 360 340 350 360 370 380 390 pF1KB8 ATPAVSWRLLSVEHEDFLTVAESLKKEFDSPETADLKFRIDGKYIHVHKAVLKIRCEHFR :::::.::::::: .: ::::::::.:::.:.:::::: .:::::..::..::::::::: XP_005 ATPAVTWRLLSVEPDDHLTVAESLKREFDNPDTADLKFLVDGKYIYAHKVLLKIRCEHFR 370 380 390 400 410 420 400 410 420 430 440 450 pF1KB8 SMFQSYWNEDMKEVIEIDQFSYPVYRAFLQYLYTDTVDLPPEDAIGLLDLATSYCENRLK : ... ::: ...:...::::::::::.:::::...: ::.:.::::::: : ::::: XP_005 SSLED--NED--DIVEMSEFSYPVYRAFLEYLYTDSISLSPEEAVGLLDLATFYRENRLK 430 440 450 460 470 460 470 480 490 500 510 pF1KB8 KLCQHIIKRGITVENAFSLFSAAVRYDAEDLEEFCFKFCINHLTEVTQTAAFWQMDGPLL ::::. ::.:: :::..:.::::.:::.:::::::.::::::: ::::..: .:: :: XP_005 KLCQQTIKQGICEENAIALLSAAVKYDAQDLEEFCFRFCINHLTVVTQTSGFAEMDHDLL 480 490 500 510 520 530 520 530 pF1KB8 KEFIAKASKCGAFKN :.::.:::. ::::: XP_005 KNFISKASRVGAFKN 540 550 531 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 13:57:50 2016 done: Fri Nov 4 13:57:51 2016 Total Scan time: 8.680 Total Display time: 0.130 Function used was FASTA [36.3.4 Apr, 2011]