FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8638, 374 aa 1>>>pF1KB8638 374 - 374 aa - 374 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1692+/-0.00031; mu= 17.4984+/- 0.019 mean_var=66.9128+/-14.595, 0's: 0 Z-trim(117.4): 309 B-trim: 2012 in 2/50 Lambda= 0.156791 statistics sampled from 28925 (29309) to 28925 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.701), E-opt: 0.2 (0.344), width: 16 Scan time: 8.190 The best scores are: opt bits E(85289) XP_005257780 (OMIM: 602650) PREDICTED: speckle-typ ( 374) 2515 577.5 1.7e-164 NP_001007228 (OMIM: 602650) speckle-type POZ prote ( 374) 2515 577.5 1.7e-164 NP_001007231 (OMIM: 602650) speckle-type POZ prote ( 374) 2515 577.5 1.7e-164 XP_005257781 (OMIM: 602650) PREDICTED: speckle-typ ( 374) 2515 577.5 1.7e-164 NP_001007230 (OMIM: 602650) speckle-type POZ prote ( 374) 2515 577.5 1.7e-164 NP_001007229 (OMIM: 602650) speckle-type POZ prote ( 374) 2515 577.5 1.7e-164 NP_001007227 (OMIM: 602650) speckle-type POZ prote ( 374) 2515 577.5 1.7e-164 NP_003554 (OMIM: 602650) speckle-type POZ protein ( 374) 2515 577.5 1.7e-164 XP_016880693 (OMIM: 602650) PREDICTED: speckle-typ ( 374) 2515 577.5 1.7e-164 XP_016867929 (OMIM: 611119,612943,617055) PREDICTE ( 325) 279 71.7 2.8e-12 NP_001026880 (OMIM: 611119,612943,617055) kelch-li ( 586) 279 71.8 4.5e-12 XP_016867930 (OMIM: 611119,612943,617055) PREDICTE ( 303) 273 70.3 6.8e-12 XP_011511576 (OMIM: 614214) PREDICTED: kelch-like ( 327) 272 70.1 8.4e-12 XP_016867928 (OMIM: 611119,612943,617055) PREDICTE ( 564) 273 70.4 1.1e-11 NP_569713 (OMIM: 614214) kelch-like protein 6 [Hom ( 621) 272 70.2 1.4e-11 NP_061334 (OMIM: 611119,612943,617055) kelch-like ( 538) 265 68.6 3.8e-11 XP_016865716 (OMIM: 611237) PREDICTED: BTB/POZ dom ( 387) 258 67.0 8.7e-11 XP_011512584 (OMIM: 611237) PREDICTED: BTB/POZ dom ( 387) 258 67.0 8.7e-11 XP_011512583 (OMIM: 611237) PREDICTED: BTB/POZ dom ( 391) 258 67.0 8.7e-11 XP_011512582 (OMIM: 611237) PREDICTED: BTB/POZ dom ( 401) 258 67.0 8.9e-11 NP_001092742 (OMIM: 611237) BTB/POZ domain-contain ( 612) 258 67.1 1.3e-10 XP_011512581 (OMIM: 611237) PREDICTED: BTB/POZ dom ( 612) 258 67.1 1.3e-10 NP_443125 (OMIM: 611237) BTB/POZ domain-containing ( 612) 258 67.1 1.3e-10 NP_001311238 (OMIM: 616262) kelch-like protein 21 ( 500) 254 66.1 2e-10 NP_055666 (OMIM: 616262) kelch-like protein 21 iso ( 597) 254 66.2 2.3e-10 NP_059111 (OMIM: 605775,614495) kelch-like protein ( 587) 244 63.9 1.1e-09 XP_011529874 (OMIM: 605774) PREDICTED: kelch-like ( 633) 244 63.9 1.2e-09 NP_001244123 (OMIM: 605775,614495) kelch-like prot ( 555) 243 63.7 1.2e-09 XP_016863164 (OMIM: 605774) PREDICTED: kelch-like ( 415) 236 62.0 2.9e-09 NP_006758 (OMIM: 600574,615670,616564) leucine-zip ( 840) 239 62.9 3.2e-09 XP_016863163 (OMIM: 605774) PREDICTED: kelch-like ( 555) 236 62.1 3.6e-09 NP_009177 (OMIM: 605774) kelch-like protein 2 isof ( 593) 236 62.1 3.8e-09 NP_001154993 (OMIM: 605774) kelch-like protein 2 i ( 597) 236 62.1 3.9e-09 XP_011511240 (OMIM: 611295) PREDICTED: kelch-like ( 600) 235 61.9 4.5e-09 NP_060114 (OMIM: 611295) kelch-like protein 24 [Ho ( 600) 235 61.9 4.5e-09 XP_005247612 (OMIM: 611295) PREDICTED: kelch-like ( 600) 235 61.9 4.5e-09 XP_005247613 (OMIM: 611295) PREDICTED: kelch-like ( 600) 235 61.9 4.5e-09 XP_005247611 (OMIM: 611295) PREDICTED: kelch-like ( 600) 235 61.9 4.5e-09 XP_016862149 (OMIM: 611295) PREDICTED: kelch-like ( 600) 235 61.9 4.5e-09 XP_005247609 (OMIM: 611295) PREDICTED: kelch-like ( 600) 235 61.9 4.5e-09 XP_005247610 (OMIM: 611295) PREDICTED: kelch-like ( 600) 235 61.9 4.5e-09 XP_016862148 (OMIM: 611295) PREDICTED: kelch-like ( 600) 235 61.9 4.5e-09 XP_016862143 (OMIM: 611295) PREDICTED: kelch-like ( 625) 235 61.9 4.7e-09 XP_016862140 (OMIM: 611295) PREDICTED: kelch-like ( 625) 235 61.9 4.7e-09 XP_016862146 (OMIM: 611295) PREDICTED: kelch-like ( 625) 235 61.9 4.7e-09 XP_016862145 (OMIM: 611295) PREDICTED: kelch-like ( 625) 235 61.9 4.7e-09 XP_016862147 (OMIM: 611295) PREDICTED: kelch-like ( 625) 235 61.9 4.7e-09 XP_016862139 (OMIM: 611295) PREDICTED: kelch-like ( 625) 235 61.9 4.7e-09 XP_016862142 (OMIM: 611295) PREDICTED: kelch-like ( 625) 235 61.9 4.7e-09 XP_016862144 (OMIM: 611295) PREDICTED: kelch-like ( 625) 235 61.9 4.7e-09 >>XP_005257780 (OMIM: 602650) PREDICTED: speckle-type PO (374 aa) initn: 2515 init1: 2515 opt: 2515 Z-score: 3074.1 bits: 577.5 E(85289): 1.7e-164 Smith-Waterman score: 2515; 100.0% identity (100.0% similar) in 374 aa overlap (1-374:1-374) 10 20 30 40 50 60 pF1KB8 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 NAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQ 310 320 330 340 350 360 370 pF1KB8 CPFLGPPRKRLKQS :::::::::::::: XP_005 CPFLGPPRKRLKQS 370 >>NP_001007228 (OMIM: 602650) speckle-type POZ protein [ (374 aa) initn: 2515 init1: 2515 opt: 2515 Z-score: 3074.1 bits: 577.5 E(85289): 1.7e-164 Smith-Waterman score: 2515; 100.0% identity (100.0% similar) in 374 aa overlap (1-374:1-374) 10 20 30 40 50 60 pF1KB8 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 NAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQ 310 320 330 340 350 360 370 pF1KB8 CPFLGPPRKRLKQS :::::::::::::: NP_001 CPFLGPPRKRLKQS 370 >>NP_001007231 (OMIM: 602650) speckle-type POZ protein [ (374 aa) initn: 2515 init1: 2515 opt: 2515 Z-score: 3074.1 bits: 577.5 E(85289): 1.7e-164 Smith-Waterman score: 2515; 100.0% identity (100.0% similar) in 374 aa overlap (1-374:1-374) 10 20 30 40 50 60 pF1KB8 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 NAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQ 310 320 330 340 350 360 370 pF1KB8 CPFLGPPRKRLKQS :::::::::::::: NP_001 CPFLGPPRKRLKQS 370 >>XP_005257781 (OMIM: 602650) PREDICTED: speckle-type PO (374 aa) initn: 2515 init1: 2515 opt: 2515 Z-score: 3074.1 bits: 577.5 E(85289): 1.7e-164 Smith-Waterman score: 2515; 100.0% identity (100.0% similar) in 374 aa overlap (1-374:1-374) 10 20 30 40 50 60 pF1KB8 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 NAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQ 310 320 330 340 350 360 370 pF1KB8 CPFLGPPRKRLKQS :::::::::::::: XP_005 CPFLGPPRKRLKQS 370 >>NP_001007230 (OMIM: 602650) speckle-type POZ protein [ (374 aa) initn: 2515 init1: 2515 opt: 2515 Z-score: 3074.1 bits: 577.5 E(85289): 1.7e-164 Smith-Waterman score: 2515; 100.0% identity (100.0% similar) in 374 aa overlap (1-374:1-374) 10 20 30 40 50 60 pF1KB8 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 NAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQ 310 320 330 340 350 360 370 pF1KB8 CPFLGPPRKRLKQS :::::::::::::: NP_001 CPFLGPPRKRLKQS 370 >>NP_001007229 (OMIM: 602650) speckle-type POZ protein [ (374 aa) initn: 2515 init1: 2515 opt: 2515 Z-score: 3074.1 bits: 577.5 E(85289): 1.7e-164 Smith-Waterman score: 2515; 100.0% identity (100.0% similar) in 374 aa overlap (1-374:1-374) 10 20 30 40 50 60 pF1KB8 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 NAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQ 310 320 330 340 350 360 370 pF1KB8 CPFLGPPRKRLKQS :::::::::::::: NP_001 CPFLGPPRKRLKQS 370 >>NP_001007227 (OMIM: 602650) speckle-type POZ protein [ (374 aa) initn: 2515 init1: 2515 opt: 2515 Z-score: 3074.1 bits: 577.5 E(85289): 1.7e-164 Smith-Waterman score: 2515; 100.0% identity (100.0% similar) in 374 aa overlap (1-374:1-374) 10 20 30 40 50 60 pF1KB8 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 NAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQ 310 320 330 340 350 360 370 pF1KB8 CPFLGPPRKRLKQS :::::::::::::: NP_001 CPFLGPPRKRLKQS 370 >>NP_003554 (OMIM: 602650) speckle-type POZ protein [Hom (374 aa) initn: 2515 init1: 2515 opt: 2515 Z-score: 3074.1 bits: 577.5 E(85289): 1.7e-164 Smith-Waterman score: 2515; 100.0% identity (100.0% similar) in 374 aa overlap (1-374:1-374) 10 20 30 40 50 60 pF1KB8 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 NAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 NAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQ 310 320 330 340 350 360 370 pF1KB8 CPFLGPPRKRLKQS :::::::::::::: NP_003 CPFLGPPRKRLKQS 370 >>XP_016880693 (OMIM: 602650) PREDICTED: speckle-type PO (374 aa) initn: 2515 init1: 2515 opt: 2515 Z-score: 3074.1 bits: 577.5 E(85289): 1.7e-164 Smith-Waterman score: 2515; 100.0% identity (100.0% similar) in 374 aa overlap (1-374:1-374) 10 20 30 40 50 60 pF1KB8 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 NAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQ 310 320 330 340 350 360 370 pF1KB8 CPFLGPPRKRLKQS :::::::::::::: XP_016 CPFLGPPRKRLKQS 370 >>XP_016867929 (OMIM: 611119,612943,617055) PREDICTED: k (325 aa) initn: 273 init1: 273 opt: 279 Z-score: 341.5 bits: 71.7 E(85289): 2.8e-12 Smith-Waterman score: 279; 32.2% identity (64.9% similar) in 174 aa overlap (183-351:23-196) 160 170 180 190 200 pF1KB8 DKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSR----FTDCCLCVAG : .: . :. .: : . : : : XP_016 MAASGVEKSSKKKTEKKLAAREEAKLLAGFMGVMNNMRKQKTLCDVILMVQE 10 20 30 40 50 210 220 230 240 250 260 pF1KB8 QEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDK ... ::...::: : :. :: .: :::. .::..:.::....... : ::.. .. XP_016 RKIPAHRVVLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSN 60 70 80 90 100 110 270 280 290 300 310 320 pF1KB8 MADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYH ...:: ::..: .: .: :: : : .... : : .::. . .::. : :::. : XP_016 NVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQH 120 130 140 150 160 170 330 340 350 360 370 pF1KB8 ASDVLETSGWKSMVVSH-PHLVAEAYRSLASAQCPFLGPPRKRLKQS ..: .:. . .. :.. ::. . XP_016 FTEVYKTDEFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAK 180 190 200 210 220 230 374 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:05:34 2016 done: Fri Nov 4 14:05:35 2016 Total Scan time: 8.190 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]