FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8641, 859 aa
1>>>pF1KB8641 859 - 859 aa - 859 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.2946+/-0.000916; mu= 13.2526+/- 0.056
mean_var=137.4123+/-27.400, 0's: 0 Z-trim(110.4): 64 B-trim: 109 in 2/51
Lambda= 0.109411
statistics sampled from 11525 (11589) to 11525 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.687), E-opt: 0.2 (0.356), width: 16
Scan time: 3.590
The best scores are: opt bits E(32554)
CCDS9918.1 DDX24 gene_id:57062|Hs108|chr14 ( 859) 5604 896.5 0
CCDS8770.1 DDX23 gene_id:9416|Hs108|chr12 ( 820) 397 74.6 8e-13
CCDS8655.1 DDX47 gene_id:51202|Hs108|chr12 ( 455) 379 71.6 3.6e-12
CCDS10858.1 DDX28 gene_id:55794|Hs108|chr16 ( 540) 365 69.4 1.9e-11
CCDS5492.1 DDX56 gene_id:54606|Hs108|chr7 ( 547) 350 67.1 9.9e-11
>>CCDS9918.1 DDX24 gene_id:57062|Hs108|chr14 (859 aa)
initn: 5604 init1: 5604 opt: 5604 Z-score: 4785.3 bits: 896.5 E(32554): 0
Smith-Waterman score: 5604; 100.0% identity (100.0% similar) in 859 aa overlap (1-859:1-859)
10 20 30 40 50 60
pF1KB8 MKLKDTKSRPKQSSCGKFQTKGIKVVGKWKEVKIDPNMFADGQMDDLVCFEELTDYQLVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 MKLKDTKSRPKQSSCGKFQTKGIKVVGKWKEVKIDPNMFADGQMDDLVCFEELTDYQLVS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PAKNPSSLFSKEAPKRKAQAVSEEEEEEEGKSSSPKKKIKLKKSKNVATEGTSTQKEFEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 PAKNPSSLFSKEAPKRKAQAVSEEEEEEEGKSSSPKKKIKLKKSKNVATEGTSTQKEFEV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 KDPELEAQGDDMVCDDPEAGEMTSENLVQTAPKKKKNKGKKGLEPSQSTAAKVPKKAKTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 KDPELEAQGDDMVCDDPEAGEMTSENLVQTAPKKKKNKGKKGLEPSQSTAAKVPKKAKTW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 IPEVHDQKADVSAWKDLFVPRPVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAETG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 IPEVHDQKADVSAWKDLFVPRPVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAETG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 SGKTLAFAIPMIHAVLQWQKRNAAPPPSNTEAPPGETRTEAGAETRSPGKAEAESDALPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 SGKTLAFAIPMIHAVLQWQKRNAAPPPSNTEAPPGETRTEAGAETRSPGKAEAESDALPD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 DTVIESEALPSDIAAEARAKTGGTVSDQALLFGDDDAGEGPSSLIREKPVPKQNENEEEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 DTVIESEALPSDIAAEARAKTGGTVSDQALLFGDDDAGEGPSSLIREKPVPKQNENEEEN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 LDKEQTGNLKQELDDKSATCKAYPKRPLLGLVLTPTRELAVQVKQHIDAVARFTGIKTAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 LDKEQTGNLKQELDDKSATCKAYPKRPLLGLVLTPTRELAVQVKQHIDAVARFTGIKTAI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 LVGGMSTQKQQRMLNRRPEIVVATPGRLWELIKEKHYHLRNLRQLRCLVVDEADRMVEKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 LVGGMSTQKQQRMLNRRPEIVVATPGRLWELIKEKHYHLRNLRQLRCLVVDEADRMVEKG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 HFAELSQLLEMLNDSQYNPKRQTLVFSATLTLVHQAPARILHKKHTKKMDKTAKLDLLMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 HFAELSQLLEMLNDSQYNPKRQTLVFSATLTLVHQAPARILHKKHTKKMDKTAKLDLLMQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 KIGMRGKPKVIDLTRNEATVETLTETKIHCETDEKDFYLYYFLMQYPGRSLVFANSISCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 KIGMRGKPKVIDLTRNEATVETLTETKIHCETDEKDFYLYYFLMQYPGRSLVFANSISCI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 KRLSGLLKVLDIMPLTLHACMHQKQRLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 KRLSGLLKVLDIMPLTLHACMHQKQRLRNLEQFARLEDCVLLATDVAARGLDIPKVQHVI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 HYQVPRTSEIYVHRSGRTARATNEGLSLMLIGPEDVINFKKIYKTLKKDEDIPLFPVQTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 HYQVPRTSEIYVHRSGRTARATNEGLSLMLIGPEDVINFKKIYKTLKKDEDIPLFPVQTK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 YMDVVKERIRLARQIEKSEYRNFQACLHNSWIEQAAAALEIELEEDMYKGGKADQQEERR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 YMDVVKERIRLARQIEKSEYRNFQACLHNSWIEQAAAALEIELEEDMYKGGKADQQEERR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB8 RQKQMKVLKKELRHLLSQPLFTESQKTKYPTQSGKPPLLVSAPSKSESALSCLSKQKKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS99 RQKQMKVLKKELRHLLSQPLFTESQKTKYPTQSGKPPLLVSAPSKSESALSCLSKQKKKK
790 800 810 820 830 840
850
pF1KB8 TKKPKEPQPEQPQPSTSAN
:::::::::::::::::::
CCDS99 TKKPKEPQPEQPQPSTSAN
850
>>CCDS8770.1 DDX23 gene_id:9416|Hs108|chr12 (820 aa)
initn: 611 init1: 190 opt: 397 Z-score: 343.7 bits: 74.6 E(32554): 8e-13
Smith-Waterman score: 398; 29.7% identity (56.8% similar) in 333 aa overlap (391-706:472-783)
370 380 390 400 410 420
pF1KB8 LDKEQTGNLKQELDDKSATCKAYPKRPLLGLVLTPTRELAVQVKQHIDAVARFTGIKTAI
..:.:::::: :.... .. ::.:.
CCDS87 TAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVA
450 460 470 480 490 500
430 440 450 460 470
pF1KB8 LVGGMSTQKQQRMLNRRPEIVVATPGRLWELIKEKHYHLRNLRQLRC--LVVDEADRMVE
..::.: . : : :::.:::::: ....... : :: .:.::::::..
CCDS87 VIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLVLS-----RCTYVVLDEADRMID
510 520 530 540 550
480 490 500 510 520 530
pF1KB8 KGHFAELSQLLEML--------NDSQYNPKRQTLVFSATLTLVHQAPARILHKKHTKKMD
: .....:: . .: .:... : . .:. .. ..
CCDS87 MGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQT--VMFTATMPPAVE
560 570 580 590 600 610
540 550 560 570 580
pF1KB8 KTAKLDL---LMQKIGMRGKPKVIDLTRNEATVETLTETKIHCETDEKDFYLYYFLMQ-Y
. :. : . :: :::. : : : ..:. :: : .: : .
CCDS87 RLARSYLRRPAVVYIGSAGKPH----ERVEQKVFLMSES-------EKRKKLLAILEQGF
620 630 640 650 660
590 600 610 620 630 640
pF1KB8 PGRSLVFANSISCIKRLSGLLKVLDIMPLTLHACMHQKQR---LRNLEQFARLEDCVLLA
..:.:. . :. :. . :::. :.:: : ::. :. : .:.:
CCDS87 DPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAK--D-ILVA
670 680 690 700 710 720
650 660 670 680 690 700
pF1KB8 TDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARATNEGLSLMLIGPEDVINFKKIY
::::.::.:: :. :..:.. .. : :.:: :::.:: . :... .. :: : ..
CCDS87 TDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYELK
730 740 750 760 770 780
710 720 730 740 750 760
pF1KB8 KTLKKDEDIPLFPVQTKYMDVVKERIRLARQIEKSEYRNFQACLHNSWIEQAAAALEIEL
...
CCDS87 QAILESPVSSCPPELANHPDAQHKPGTILTKKRREETIFA
790 800 810 820
>>CCDS8655.1 DDX47 gene_id:51202|Hs108|chr12 (455 aa)
initn: 692 init1: 280 opt: 379 Z-score: 332.0 bits: 71.6 E(32554): 3.6e-12
Smith-Waterman score: 639; 34.2% identity (64.7% similar) in 360 aa overlap (384-741:90-415)
360 370 380 390 400 410
pF1KB8 NENEEENLDKEQTGNLKQELDDKSATCKAYPKRPLLGLVLTPTRELAVQVKQHIDAVARF
:.: :..:::::::::: :......:..
CCDS86 QGRDIIGLAETGSGKTGAFALPILNALLETPQR-LFALVLTPTRELAFQISEQFEALGSS
60 70 80 90 100 110
420 430 440 450 460 470
pF1KB8 TGIKTAILVGGMSTQKQQRMLNRRPEIVVATPGRLWELIKEKHYHLRNLRQLRCLVVDEA
:...:..:::.....:. : ..:.:..:::::: . ... . ::: :. ::.:::
CCDS86 IGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGF--NLRALKYLVMDEA
120 130 140 150 160 170
480 490 500 510 520 530
pF1KB8 DRMVEKGHFAELSQLLEMLNDSQYNPK-RQTLVFSATLTLVHQAPARILHKKHTKKMDKT
::... .:....:... :. :.:..::::.: ::..:
CCDS86 DRILNMDFETEVDKILKVI------PRDRKTFLFSATMT---------------KKVQK-
180 190 200 210
540 550 560 570 580 590
pF1KB8 AKLDLLMQKIGMRGKPKVIDLTRNEATVETLTETKIHCETDEKDFYLYYFLMQYPGRS-L
.:. .... : .. . ::: : . : . :: :: :.: . : : .
CCDS86 ------LQRAALKNPVKCA-VSSKYQTVEKLQQYYIFIPSKFKDTYLVYILNELAGNSFM
220 230 240 250 260
600 610 620 630 640 650
pF1KB8 VFANSISCIKRLSGLLKVLDIMPLTLHACMHQKQRLRNLEQFARLEDCVLLATDVAARGL
.: .. . .: . ::. : . . ::. : :..:: .:..: .:::::::.:::
CCDS86 IFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGL
270 280 290 300 310 320
660 670 680 690 700 710
pF1KB8 DIPKVQHVIHYQVPRTSEIYVHRSGRTARATNEGLSLMLIGPEDVINFKKIYKTLKKDED
:::.:. :.....: :. :.:: :::::: : .. .. :: :..: . . :
CCDS86 DIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKK--
330 340 350 360 370 380
720 730 740 750 760 770
pF1KB8 IPLFPVQTKYMDVVKERIRLARQIEKSEYRNFQACLHNSWIEQAAAALEIELEEDMYKGG
.: ::.: . .. ::. :... . : :
CCDS86 LPGFPTQDDEVMMLTERVAEAQRFARMELREHGEKKKRSREDAGDNDDTEGAIGVRNKVA
390 400 410 420 430 440
>>CCDS10858.1 DDX28 gene_id:55794|Hs108|chr16 (540 aa)
initn: 450 init1: 190 opt: 365 Z-score: 319.0 bits: 69.4 E(32554): 1.9e-11
Smith-Waterman score: 395; 29.3% identity (57.1% similar) in 338 aa overlap (390-713:206-526)
360 370 380 390 400 410
pF1KB8 NLDKEQTGNLKQELDDKSATCKAYPKRPLLGLVLTPTRELAVQVKQHIDAVARFTGIKTA
::::.:.:::: ::. . ..: :. .
CCDS10 SGKTLSYLLPLLQRLLGQPSLDSLPIPAPRGLVLVPSRELAQQVRAVAQPLGRSLGLLVR
180 190 200 210 220 230
420 430 440 450 460 470
pF1KB8 ILVGGMSTQKQQRMLNRRP--EIVVATPGRLWELIKEKHYHLRNLRQLRCLVVDEADRMV
: :: . .. . .:.:.: ...::::: ::. .: . : .:.:: ::.:::: ..
CCDS10 DLEGGHGMRRIRLQLSRQPSADVLVATPGALWKALKSR---LISLEQLSFLVLDEADTLL
240 250 260 270 280 290
480 490 500 510 520
pF1KB8 EKGHFAELSQLLEMLN--------DSQYNPKRQTLVFSATLTL-VHQAPARILHKKHTKK
... . .. .:: . .. .::: : .. .::. : : .. .
CCDS10 DESFLELVDYILEKSHIAEGPADLEDPFNPKAQLVLVGATFPEGVGQLLNKVASPDAVTT
300 310 320 330 340 350
530 540 550 560 570 580
pF1KB8 MDKTAKLDLLMQKIGMRGKPKVIDLTRNEATVETLTETKIHCETDEKDFYLYYFLMQYPG
. ..:: .: .. : . : . ..: . : : . :. :
CCDS10 IT-SSKLHCIMPHV----KQTFLRLKGADKVAELVHILK-HRDRAERT--------GPSG
360 370 380 390
590 600 610 620 630 640
pF1KB8 RSLVFANSISCIKRLSGLLKVLDIMPLTLHACMHQKQRLRNLEQFARLEDCVLLATDVAA
::: :: : .. :. .: :. : :.. : .:. ...: . .:: ::.:.
CCDS10 TVLVFCNSSSTVNWLGYILDDHKIQHLRLQGQMPALMRVGIFQSFQKSSRDILLCTDIAS
400 410 420 430 440 450
650 660 670 680 690 700
pF1KB8 RGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARATNE--GLSLMLIG-PEDVINFKKIYKT
:::: :. :..:. : : . :.::.::..:. .: : . .. : :: .:: .
CCDS10 RGLDSTGVELVVNYDFPPTLQDYIHRAGRVGRVGSEVPGTVISFVTHPWDVSLVQKIELA
460 470 480 490 500 510
710 720 730 740 750 760
pF1KB8 LKKDEDIPLFPVQTKYMDVVKERIRLARQIEKSEYRNFQACLHNSWIEQAAAALEIELEE
.. ...:
CCDS10 ARRRRSLPGLASSVKEPLPQAT
520 530 540
>>CCDS5492.1 DDX56 gene_id:54606|Hs108|chr7 (547 aa)
initn: 385 init1: 168 opt: 350 Z-score: 306.1 bits: 67.1 E(32554): 9.9e-11
Smith-Waterman score: 456; 27.9% identity (54.3% similar) in 567 aa overlap (327-844:15-529)
300 310 320 330 340 350
pF1KB8 ALPDDTVIESEALPSDIAAEARAKTGGTVSDQALLFGDDDAGEGPSSLIREKPVPKQNEN
: :: . : : . .::.:: .: :.
CCDS54 MEDSEALGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEG
10 20 30 40
360 370 380 390 400
pF1KB8 EEENLDKEQTGNLK---------QELDDKSATCKAYPKRPLLGLVLTPTRELAVQVKQHI
.. : . .::. : : : ..:: . .. . ::::.::.::: :... :
CCDS54 KDL-LARARTGSGKTAAYAIPMLQLLLHRKATGPVV-EQAVRGLVLVPTKELARQAQSMI
50 60 70 80 90 100
410 420 430 440 450 460
pF1KB8 DAVARFTG--IKTAILVGGMSTQKQQRMLNRRPEIVVATPGRLWELIKEKHYHLRNLRQL
. .: . . ...: . .. .. .:. .: ..:..::.::.:. ... .::. .:
CCDS54 QQLATYCARDVRVANVSAAEDSVSQRAVLMEKPDVVVGTPSRILSHLQQDSLKLRD--SL
110 120 130 140 150 160
470 480 490 500 510 520
pF1KB8 RCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPK-RQTLVFSATLTLVHQAPAR-ILHK
. ::::::: . : ::..:: : :. :....:::.. :: . :::.
CCDS54 ELLVVDEADLLFSFGFEEELKSLLCHL------PRIYQAFLMSATFNEDVQALKELILHN
170 180 190 200 210
530 540 550 560 570 580
pF1KB8 KHTKKMDKTAKLDLLMQKIGMRGKPKVIDLTRNEATVETLTETKIHCETDEKDFYLYYFL
: :.... : : : . : . .. :::.: : : : :
CCDS54 PVTLKLQES-------QLPG----P------------DQLQQFQVVCETEEDKFLLLYAL
220 230 240 250
590 600 610 620 630
pF1KB8 MQYP---GRSLVFANSISCIKRLSGLLKVLDIMPLTLHACMHQKQRLRNLEQFAR-LEDC
.. :.::.:.:.. :: .:. ..: .:.. . ..: . . :: . . ::
CCDS54 LKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQFNQGFYDC
260 270 280 290 300 310
640 650 660 670
pF1KB8 VLLATDV---------------------------AARGLDIPKVQHVIHYQVPRTSEIYV
:. :::. .:::.:. .:. :.....: : : :.
CCDS54 VI-ATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLPPTPEAYI
320 330 340 350 360 370
680 690 700 710 720 730
pF1KB8 HRSGRTARATNEGLSLMLIGPEDVINFKKIYKTLKKDEDIP-LFPVQTKYMDVVKERIRL
::.::::::.: :. : .. : . ... :: . :. .. : :.: : .. .. : :
CCDS54 HRAGRTARANNPGIVLTFVLPTEQFHLGKIEELLSGENRGPILLPYQFRMEEIEGFRYR-
380 390 400 410 420
740 750 760 770 780 790
pF1KB8 ARQIEKSEYRNFQACLHNSWIEQAAAALEIELEEDMYKGGKADQQ-EERRRQKQMKVLKK
:. .: . :: :..: :..:.. .. : :. :. :.
CCDS54 CRDAMRSVTK--QA------IREARLK---EIKEELLHSEKLKTYFEDNPRDLQL-----
430 440 450 460 470
800 810 820 830 840
pF1KB8 ELRHLLS-QPLFTESQKTKYPTQSGKPPL--LVSAPSKSESALSCLSKQKKKKTKKPKEP
::: : .: .. . . : : : :: .: .. : : :. :...:
CCDS54 -LRHDLPLHPAVVKPHLGHVPDYLVPPALRGLVRPHKKRKKLSSSCRKAKRAKSQNPLRS
480 490 500 510 520 530
850
pF1KB8 QPEQPQPSTSAN
CCDS54 FKHKGKKFRPTAKPS
540
859 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 14:06:33 2016 done: Fri Nov 4 14:06:34 2016
Total Scan time: 3.590 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]