Result of FASTA (ccds) for pF1KB8643
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8643, 517 aa
  1>>>pF1KB8643 517 - 517 aa - 517 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.9233+/-0.000867; mu= 7.4267+/- 0.053
 mean_var=146.0100+/-29.540, 0's: 0 Z-trim(111.6): 30  B-trim: 178 in 1/53
 Lambda= 0.106141
 statistics sampled from 12460 (12485) to 12460 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.729), E-opt: 0.2 (0.384), width:  16
 Scan time:  3.220

The best scores are:                                      opt bits E(32554)
CCDS14078.1 TBC1D22A gene_id:25771|Hs108|chr22     ( 517) 3497 547.0 1.9e-155
CCDS74877.1 TBC1D22A gene_id:25771|Hs108|chr22     ( 487) 3218 504.3 1.3e-142
CCDS63512.1 TBC1D22A gene_id:25771|Hs108|chr22     ( 470) 3170 496.9  2e-140
CCDS63511.1 TBC1D22A gene_id:25771|Hs108|chr22     ( 439) 2100 333.1 4.1e-91
CCDS4832.1 TBC1D22B gene_id:55633|Hs108|chr6       ( 505) 1805 287.9 1.8e-77


>>CCDS14078.1 TBC1D22A gene_id:25771|Hs108|chr22          (517 aa)
 initn: 3497 init1: 3497 opt: 3497  Z-score: 2904.4  bits: 547.0 E(32554): 1.9e-155
Smith-Waterman score: 3497; 100.0% identity (100.0% similar) in 517 aa overlap (1-517:1-517)

               10        20        30        40        50        60
pF1KB8 MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVST
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 FQEFESNTSDAWDAGEDDDELLAMAAESLNSEVVMETANRVLRNHSQRQGRPTLQEGPGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 FQEFESNTSDAWDAGEDDDELLAMAAESLNSEVVMETANRVLRNHSQRQGRPTLQEGPGL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 QQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 QQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 DPSTLSSSALSEREASRLDKFKQLLAGPNTDLEELRRLSWSGIPKPVRPMTWKLLSGYLP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 DPSTLSSSALSEREASRLDKFKQLLAGPNTDLEELRRLSWSGIPKPVRPMTWKLLSGYLP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 ANVDRRPATLQRKQKEYFAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQPKVTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 ANVDRRPATLQRKQKEYFAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQPKVTE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 IFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIEAEEVDTVDVSGVPAEVLCNIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 IFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIEAEEVDTVDVSGVPAEVLCNIE
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 ADTYWCMSKLLDGIQDNYTFAQPGIQMKVKMLEELVSRIDEQVHRHLDQHEVRYLQFAFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 ADTYWCMSKLLDGIQDNYTFAQPGIQMKVKMLEELVSRIDEQVHRHLDQHEVRYLQFAFR
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB8 WMNNLLMREVPLRCTIRLWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQELLLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 WMNNLLMREVPLRCTIRLWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQELLLF
              430       440       450       460       470       480

              490       500       510       
pF1KB8 LQNLPTAHWDDEDISLLLAEAYRLKFAFADAPNHYKK
       :::::::::::::::::::::::::::::::::::::
CCDS14 LQNLPTAHWDDEDISLLLAEAYRLKFAFADAPNHYKK
              490       500       510       

>>CCDS74877.1 TBC1D22A gene_id:25771|Hs108|chr22          (487 aa)
 initn: 3218 init1: 3218 opt: 3218  Z-score: 2673.9  bits: 504.3 E(32554): 1.3e-142
Smith-Waterman score: 3218; 99.8% identity (100.0% similar) in 479 aa overlap (39-517:9-487)

       10        20        30        40        50        60        
pF1KB8 QFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNT
                                     :.::::::::::::::::::::::::::::
CCDS74                       MWEPQPDVGSLLRSTAKMPTTPVKAKRVSTFQEFESNT
                                     10        20        30        

       70        80        90       100       110       120        
pF1KB8 SDAWDAGEDDDELLAMAAESLNSEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 SDAWDAGEDDDELLAMAAESLNSEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEA
       40        50        60        70        80        90        

      130       140       150       160       170       180        
pF1KB8 EPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTSDPSTLSSS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 EPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTSDPSTLSSS
      100       110       120       130       140       150        

      190       200       210       220       230       240        
pF1KB8 ALSEREASRLDKFKQLLAGPNTDLEELRRLSWSGIPKPVRPMTWKLLSGYLPANVDRRPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 ALSEREASRLDKFKQLLAGPNTDLEELRRLSWSGIPKPVRPMTWKLLSGYLPANVDRRPA
      160       170       180       190       200       210        

      250       260       270       280       290       300        
pF1KB8 TLQRKQKEYFAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQPKVTEIFERILFI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 TLQRKQKEYFAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQPKVTEIFERILFI
      220       230       240       250       260       270        

      310       320       330       340       350       360        
pF1KB8 WAIRHPASGYVQGINDLVTPFFVVFICEYIEAEEVDTVDVSGVPAEVLCNIEADTYWCMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 WAIRHPASGYVQGINDLVTPFFVVFICEYIEAEEVDTVDVSGVPAEVLCNIEADTYWCMS
      280       290       300       310       320       330        

      370       380       390       400       410       420        
pF1KB8 KLLDGIQDNYTFAQPGIQMKVKMLEELVSRIDEQVHRHLDQHEVRYLQFAFRWMNNLLMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 KLLDGIQDNYTFAQPGIQMKVKMLEELVSRIDEQVHRHLDQHEVRYLQFAFRWMNNLLMR
      340       350       360       370       380       390        

      430       440       450       460       470       480        
pF1KB8 EVPLRCTIRLWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQELLLFLQNLPTAH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS74 EVPLRCTIRLWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQELLLFLQNLPTAH
      400       410       420       430       440       450        

      490       500       510       
pF1KB8 WDDEDISLLLAEAYRLKFAFADAPNHYKK
       :::::::::::::::::::::::::::::
CCDS74 WDDEDISLLLAEAYRLKFAFADAPNHYKK
      460       470       480       

>>CCDS63512.1 TBC1D22A gene_id:25771|Hs108|chr22          (470 aa)
 initn: 3170 init1: 3170 opt: 3170  Z-score: 2634.4  bits: 496.9 E(32554): 2e-140
Smith-Waterman score: 3170; 100.0% identity (100.0% similar) in 470 aa overlap (48-517:1-470)

        20        30        40        50        60        70       
pF1KB8 LPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVSTFQEFESNTSDAWDAGED
                                     ::::::::::::::::::::::::::::::
CCDS63                               MPTTPVKAKRVSTFQEFESNTSDAWDAGED
                                             10        20        30

        80        90       100       110       120       130       
pF1KB8 DDELLAMAAESLNSEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 DDELLAMAAESLNSEVVMETANRVLRNHSQRQGRPTLQEGPGLQQKPRPEAEPPSPPSGD
               40        50        60        70        80        90

       140       150       160       170       180       190       
pF1KB8 LRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTSDPSTLSSSALSEREASR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 LRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTSDPSTLSSSALSEREASR
              100       110       120       130       140       150

       200       210       220       230       240       250       
pF1KB8 LDKFKQLLAGPNTDLEELRRLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 LDKFKQLLAGPNTDLEELRRLSWSGIPKPVRPMTWKLLSGYLPANVDRRPATLQRKQKEY
              160       170       180       190       200       210

       260       270       280       290       300       310       
pF1KB8 FAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQPKVTEIFERILFIWAIRHPASG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 FAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQPKVTEIFERILFIWAIRHPASG
              220       230       240       250       260       270

       320       330       340       350       360       370       
pF1KB8 YVQGINDLVTPFFVVFICEYIEAEEVDTVDVSGVPAEVLCNIEADTYWCMSKLLDGIQDN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 YVQGINDLVTPFFVVFICEYIEAEEVDTVDVSGVPAEVLCNIEADTYWCMSKLLDGIQDN
              280       290       300       310       320       330

       380       390       400       410       420       430       
pF1KB8 YTFAQPGIQMKVKMLEELVSRIDEQVHRHLDQHEVRYLQFAFRWMNNLLMREVPLRCTIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 YTFAQPGIQMKVKMLEELVSRIDEQVHRHLDQHEVRYLQFAFRWMNNLLMREVPLRCTIR
              340       350       360       370       380       390

       440       450       460       470       480       490       
pF1KB8 LWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQELLLFLQNLPTAHWDDEDISLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 LWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQELLLFLQNLPTAHWDDEDISLL
              400       410       420       430       440       450

       500       510       
pF1KB8 LAEAYRLKFAFADAPNHYKK
       ::::::::::::::::::::
CCDS63 LAEAYRLKFAFADAPNHYKK
              460       470

>>CCDS63511.1 TBC1D22A gene_id:25771|Hs108|chr22          (439 aa)
 initn: 2256 init1: 2100 opt: 2100  Z-score: 1749.3  bits: 333.1 E(32554): 4.1e-91
Smith-Waterman score: 2814; 84.9% identity (84.9% similar) in 517 aa overlap (1-517:1-439)

               10        20        30        40        50        60
pF1KB8 MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVST
       :::::::::::::::::::::                   ::::::::::::::::::::
CCDS63 MASDGARKQFWKRSNSKLPGS-------------------LLRSTAKMPTTPVKAKRVST
               10        20                           30        40 

               70        80        90       100       110       120
pF1KB8 FQEFESNTSDAWDAGEDDDELLAMAAESLNSEVVMETANRVLRNHSQRQGRPTLQEGPGL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 FQEFESNTSDAWDAGEDDDELLAMAAESLNSEVVMETANRVLRNHSQRQGRPTLQEGPGL
              50        60        70        80        90       100 

              130       140       150       160       170       180
pF1KB8 QQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTLGGTS
       ::::::::::::::::::::::::::::::::::                          
CCDS63 QQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAE--------------------------
             110       120       130                               

              190       200       210       220       230       240
pF1KB8 DPSTLSSSALSEREASRLDKFKQLLAGPNTDLEELRRLSWSGIPKPVRPMTWKLLSGYLP
                                        :::::::::::::::::::::::::::
CCDS63 ---------------------------------ELRRLSWSGIPKPVRPMTWKLLSGYLP
                                          140       150       160  

              250       260       270       280       290       300
pF1KB8 ANVDRRPATLQRKQKEYFAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQPKVTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 ANVDRRPATLQRKQKEYFAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEALILQPKVTE
            170       180       190       200       210       220  

              310       320       330       340       350       360
pF1KB8 IFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIEAEEVDTVDVSGVPAEVLCNIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 IFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIEAEEVDTVDVSGVPAEVLCNIE
            230       240       250       260       270       280  

              370       380       390       400       410       420
pF1KB8 ADTYWCMSKLLDGIQDNYTFAQPGIQMKVKMLEELVSRIDEQVHRHLDQHEVRYLQFAFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 ADTYWCMSKLLDGIQDNYTFAQPGIQMKVKMLEELVSRIDEQVHRHLDQHEVRYLQFAFR
            290       300       310       320       330       340  

              430       440       450       460       470       480
pF1KB8 WMNNLLMREVPLRCTIRLWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQELLLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 WMNNLLMREVPLRCTIRLWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQELLLF
            350       360       370       380       390       400  

              490       500       510       
pF1KB8 LQNLPTAHWDDEDISLLLAEAYRLKFAFADAPNHYKK
       :::::::::::::::::::::::::::::::::::::
CCDS63 LQNLPTAHWDDEDISLLLAEAYRLKFAFADAPNHYKK
            410       420       430         

>>CCDS4832.1 TBC1D22B gene_id:55633|Hs108|chr6            (505 aa)
 initn: 2100 init1: 1454 opt: 1805  Z-score: 1504.3  bits: 287.9 E(32554): 1.8e-77
Smith-Waterman score: 2145; 61.5% identity (82.1% similar) in 520 aa overlap (1-517:1-505)

               10        20        30        40        50        60
pF1KB8 MASDGARKQFWKRSNSKLPGSIQHVYGAQHPPFDPLLHGTLLRSTAKMPTTPVKAKRVST
       ::.... ::::::: .::::::: ::::::::.:: :  ....  .:. :.:.: :..:.
CCDS48 MAAENS-KQFWKRS-AKLPGSIQPVYGAQHPPLDPRLTKNFIKERSKVNTVPLKNKKASS
                10         20        30        40        50        

               70        80         90       100       110         
pF1KB8 FQEFESNTSDAWDAGEDDDELLAMAA-ESLNSEVVMETANRVLRNHSQRQGRPTLQEGPG
       :.::  ::::::: :.:..: ..  . ..:::.:.. :: .::.:::.            
CCDS48 FHEFARNTSDAWDIGDDEEEDFSSPSFQTLNSKVALATAAQVLENHSK------------
       60        70        80        90       100                  

     120       130       140       150       160       170         
pF1KB8 LQQKPRPEAEPPSPPSGDLRLVKSVSESHTSCPAESASDAAPLQRSQSLPHSATVTL-GG
       :. ::.      :   .. ...:: :... :  . ..    ::...::::    . : . 
CCDS48 LRVKPERSQSTTSDVPANYKVIKSSSDAQLSRNSSDTCLRNPLHKQQSLPLRPIIPLVAR
        110       120       130       140       150       160      

      180       190       200       210       220       230        
pF1KB8 TSDPSTLSSSALSEREASRLDKFKQLLAGPNTDLEELRRLSWSGIPKPVRPMTWKLLSGY
        :: .. ..  .. :: .::.::.:::.. ::::.:::. :: :.:. :::.::.:::::
CCDS48 ISDQNASGAPPMTVREKTRLEKFRQLLSSQNTDLDELRKCSWPGVPREVRPITWRLLSGY
        170       180       190       200       210       220      

      240       250       260       270       280       290        
pF1KB8 LPANVDRRPATLQRKQKEYFAFIEHYYDSRNDEVHQDTYRQIHIDIPRMSPEA-LILQPK
       ::::..::  :::::..:::.:::.::::::.: :::::::::::::: .:   :. :: 
CCDS48 LPANTERRKLTLQRKREEYFGFIEQYYDSRNEEHHQDTYRQIHIDIPRTNPLIPLFQQPL
        230       240       250       260       270       280      

       300       310       320       330       340       350       
pF1KB8 VTEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFICEYIEAEEVDTVDVSGVPAEVLC
       : ::::::::::::::::::::::::::::::::::. ::.: :.:.. ::...  ..: 
CCDS48 VQEIFERILFIWAIRHPASGYVQGINDLVTPFFVVFLSEYVE-EDVENFDVTNLSQDMLR
        290       300       310       320        330       340     

       360       370       380       390       400       410       
pF1KB8 NIEADTYWCMSKLLDGIQDNYTFAQPGIQMKVKMLEELVSRIDEQVHRHLDQHEVRYLQF
       .::::..:::::::::::::::::::::: ::: ::::::::::::: :. ..::.::::
CCDS48 SIEADSFWCMSKLLDGIQDNYTFAQPGIQKKVKALEELVSRIDEQVHNHFRRYEVEYLQF
         350       360       370       380       390       400     

       420       430       440       450       460       470       
pF1KB8 AFRWMNNLLMREVPLRCTIRLWDTYQSEPDGFSHFHLYVCAAFLVRWRKEILEEKDFQEL
       ::::::::::::.::::::::::::::::.::::::::::::::..::::::.:.::: :
CCDS48 AFRWMNNLLMRELPLRCTIRLWDTYQSEPEGFSHFHLYVCAAFLIKWRKEILDEEDFQGL
         410       420       430       440       450       460     

       480       490       500       510       
pF1KB8 LLFLQNLPTAHWDDEDISLLLAEAYRLKFAFADAPNHYKK
       :..:::::: :: .:.:.::::::::::. ::::::::..
CCDS48 LMLLQNLPTIHWGNEEIGLLLAEAYRLKYMFADAPNHYRR
         470       480       490       500     




517 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 21:35:07 2016 done: Sat Nov  5 21:35:08 2016
 Total Scan time:  3.220 Total Display time:  0.040

Function used was FASTA [36.3.4 Apr, 2011]
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