Result of FASTA (omim) for
pF1KB8647
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8647, 824 aa
1>>>pF1KB8647 824 - 824 aa - 824 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4728+/-0.000529; mu= 15.1533+/- 0.032
mean_var=161.5321+/-31.664, 0's: 0 Z-trim(113.4): 402 B-trim: 150 in 1/50
Lambda= 0.100912
statistics sampled from 22212 (22701) to 22212 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.266), width: 16
Scan time: 11.650
The best scores are: opt bits E(85289)
NP_001275929 (OMIM: 206200,609862) transmembrane p ( 824) 5785 855.8 0
NP_001275930 (OMIM: 206200,609862) transmembrane p ( 802) 4926 730.7 6e-210
NP_705837 (OMIM: 206200,609862) transmembrane prot ( 811) 4926 730.7 6.1e-210
XP_011528291 (OMIM: 206200,609862) PREDICTED: tran ( 680) 3959 589.9 1.3e-167
XP_016862358 (OMIM: 257920,600521) PREDICTED: mann ( 702) 496 85.7 7.8e-16
NP_624302 (OMIM: 257920,600521) mannan-binding lec ( 728) 496 85.7 8e-16
XP_011511291 (OMIM: 257920,600521) PREDICTED: mann ( 735) 496 85.7 8e-16
NP_690851 (OMIM: 613797) serine protease 33 precur ( 280) 486 83.8 1.2e-15
XP_011520753 (OMIM: 613797) PREDICTED: serine prot ( 280) 486 83.8 1.2e-15
XP_011520754 (OMIM: 613797) PREDICTED: serine prot ( 280) 486 83.8 1.2e-15
XP_016878460 (OMIM: 610560) PREDICTED: polyserase- ( 621) 470 81.9 9.9e-15
XP_016878459 (OMIM: 610560) PREDICTED: polyserase- ( 634) 470 81.9 1e-14
XP_016878458 (OMIM: 610560) PREDICTED: polyserase- ( 637) 470 81.9 1e-14
NP_001245220 (OMIM: 610560) polyserase-2 isoform 3 ( 752) 470 82.0 1.1e-14
XP_016878457 (OMIM: 610560) PREDICTED: polyserase- ( 761) 470 82.0 1.1e-14
NP_001245219 (OMIM: 610560) polyserase-2 isoform 2 ( 850) 470 82.0 1.2e-14
NP_775773 (OMIM: 610560) polyserase-2 isoform 1 pr ( 855) 470 82.0 1.2e-14
NP_001275679 (OMIM: 606751) transmembrane protease ( 413) 452 79.0 4.7e-14
NP_001275680 (OMIM: 606751) transmembrane protease ( 448) 452 79.1 4.9e-14
NP_110397 (OMIM: 606751) transmembrane protease se ( 457) 452 79.1 5e-14
NP_114154 (OMIM: 608018) serine protease 27 isofor ( 290) 437 76.7 1.7e-13
NP_001298186 (OMIM: 176930,188050,601367,613679,61 ( 606) 434 76.6 3.7e-13
NP_000497 (OMIM: 176930,188050,601367,613679,61439 ( 622) 434 76.6 3.7e-13
XP_011528035 (OMIM: 602060) PREDICTED: transmembra ( 384) 428 75.5 5e-13
XP_011528034 (OMIM: 602060) PREDICTED: transmembra ( 410) 428 75.5 5.2e-13
XP_005261100 (OMIM: 602060) PREDICTED: transmembra ( 452) 428 75.6 5.6e-13
NP_005647 (OMIM: 602060) transmembrane protease se ( 492) 428 75.6 5.9e-13
XP_011528033 (OMIM: 602060) PREDICTED: transmembra ( 492) 428 75.6 5.9e-13
NP_001128571 (OMIM: 602060) transmembrane protease ( 529) 428 75.7 6.2e-13
XP_005255530 (OMIM: 609343) PREDICTED: brain-speci ( 317) 422 74.5 8.1e-13
NP_071402 (OMIM: 609343) brain-specific serine pro ( 317) 422 74.5 8.1e-13
NP_002764 (OMIM: 600823) prostasin preproprotein [ ( 343) 420 74.3 1e-12
XP_016863655 (OMIM: 217030,610984,612923,615439) P ( 535) 413 73.5 2.8e-12
XP_016863653 (OMIM: 217030,610984,612923,615439) P ( 547) 413 73.5 2.9e-12
NP_115780 (OMIM: 605511) transmembrane protease se ( 327) 408 72.5 3.4e-12
NP_076927 (OMIM: 605511) transmembrane protease se ( 454) 408 72.7 4.2e-12
NP_001193718 (OMIM: 610050) transmembrane protease ( 532) 409 72.9 4.2e-12
NP_001231924 (OMIM: 610050) transmembrane protease ( 563) 409 72.9 4.4e-12
NP_001070731 (OMIM: 610050) transmembrane protease ( 567) 409 72.9 4.4e-12
NP_001034592 (OMIM: 610561) serine protease 53 pre ( 553) 408 72.8 4.8e-12
XP_011544122 (OMIM: 610561) PREDICTED: serine prot ( 567) 408 72.8 4.9e-12
NP_001257381 (OMIM: 608159) testisin isoform 4 pre ( 225) 402 71.5 4.9e-12
XP_011544121 (OMIM: 610561) PREDICTED: serine prot ( 576) 408 72.8 4.9e-12
XP_016878366 (OMIM: 608159) PREDICTED: testisin is ( 284) 402 71.6 5.7e-12
XP_016878364 (OMIM: 608159) PREDICTED: testisin is ( 298) 402 71.6 5.9e-12
NP_659205 (OMIM: 608159) testisin isoform 2 prepro ( 312) 402 71.6 6e-12
XP_006714273 (OMIM: 217030,610984,612923,615439) P ( 531) 405 72.3 6.3e-12
XP_011530222 (OMIM: 217030,610984,612923,615439) P ( 555) 405 72.3 6.5e-12
NP_036599 (OMIM: 609341) tryptase gamma preproprot ( 321) 401 71.5 6.8e-12
XP_011520749 (OMIM: 609341) PREDICTED: tryptase ga ( 346) 401 71.5 7.1e-12
>>NP_001275929 (OMIM: 206200,609862) transmembrane prote (824 aa)
initn: 5785 init1: 5785 opt: 5785 Z-score: 4565.9 bits: 855.8 E(85289): 0
Smith-Waterman score: 5785; 100.0% identity (100.0% similar) in 824 aa overlap (1-824:1-824)
10 20 30 40 50 60
pF1KB8 MPVAEAPQVAGGQGDGGDGEEAEPEGMFKACEDSKRKARGYLRLVPLFVLLALLVLASAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPVAEAPQVAGGQGDGGDGEEAEPEGMFKACEDSKRKARGYLRLVPLFVLLALLVLASAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VLLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQDLTRRESSAFRSETAKAQKMLKELITST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQDLTRRESSAFRSETAKAQKMLKELITST
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RLGTYYNSSSVYSFGEGPLTCFFWFILQIPEHRRLMLSPEVVQALLVEELLSTVNSSAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLGTYYNSSSVYSFGEGPLTCFFWFILQIPEHRRLMLSPEVVQALLVEELLSTVNSSAAV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 PYRAEYEVDPEGLVILEASVKDIAALNSTLGCYRYSYVGQGQVLRLKGPDHLASSCLWHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PYRAEYEVDPEGLVILEASVKDIAALNSTLGCYRYSYVGQGQVLRLKGPDHLASSCLWHL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 QGPKDLMLKLRLEWTLAECRDRLAMYDVAGPLEKRLITSVYGCSRQEPVVEVLASGAIMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGPKDLMLKLRLEWTLAECRDRLAMYDVAGPLEKRLITSVYGCSRQEPVVEVLASGAIMA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 VVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQGVLSTPYFPSYYSPQTHCSWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQGVLSTPYFPSYYSPQTHCSWH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 LTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRLCGLRILQPYAERIPVVATAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRLCGLRILQPYAERIPVVATAG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 ITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVPACDGVKDCPNGLDERNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVPACDGVKDCPNGLDERNC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 VCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 QCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIAD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 RWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 ALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGALRADAVALFYGWRNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGALRADAVALFYGWRNQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 GSETCCCPISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKKDACQGDSGGPLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSETCCCPISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKKDACQGDSGGPLV
730 740 750 760 770 780
790 800 810 820
pF1KB8 CKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
::::::::::::::::::::::::::::::::::::::::::::
NP_001 CKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
790 800 810 820
>>NP_001275930 (OMIM: 206200,609862) transmembrane prote (802 aa)
initn: 4926 init1: 4926 opt: 4926 Z-score: 3890.2 bits: 730.7 E(85289): 6e-210
Smith-Waterman score: 5558; 97.2% identity (97.3% similar) in 824 aa overlap (1-824:1-802)
10 20 30 40 50 60
pF1KB8 MPVAEAPQVAGGQGDGGDGEEAEPEGMFKACEDSKRKARGYLRLVPLFVLLALLVLASAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPVAEAPQVAGGQGDGGDGEEAEPEGMFKACEDSKRKARGYLRLVPLFVLLALLVLASAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VLLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQDLTRRESSAFRSETAKAQKMLKELITST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQDLTRRESSAFRSETAKAQKMLKELITST
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RLGTYYNSSSVYSFGEGPLTCFFWFILQIPEHRRLMLSPEVVQALLVEELLSTVNSSAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLGTYYNSSSVYSFGEGPLTCFFWFILQIPEHRRLMLSPEVVQALLVEELLSTVNSSAAV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 PYRAEYEVDPEGLVILEASVKDIAALNSTLGCYRYSYVGQGQVLRLKGPDHLASSCLWHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PYRAEYEVDPEGLVILEASVKDIAALNSTLGCYRYSYVGQGQVLRLKGPDHLASSCLWHL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 QGPKDLMLKLRLEWTLAECRDRLAMYDVAGPLEKRLITSVYGCSRQEPVVEVLASGAIMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGPKDLMLKLRLEWTLAECRDRLAMYDVAGPLEKRLITSVYGCSRQEPVVEVLASGAIMA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 VVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQGVLSTPYFPSYYSPQTHCSWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQGVLSTPYFPSYYSPQTHCSWH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 LTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRLCGLRILQPYAERIPVVATAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRLCGLRILQPYAERIPVVATAG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 ITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVPACDGVKDCPNGLDERNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVPACDGVKDCPNGLDERNC
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 VCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 QCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIAD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 RWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 ALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGALRADAVALFYGWRNQ
::::::::::::::::::::::::::::::::::::::::::::.
NP_001 ALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGG---------------
670 680 690 700
730 740 750 760 770 780
pF1KB8 GSETCCCPISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKKDACQGDSGGPLV
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -------PISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKKDACQGDSGGPLV
710 720 730 740 750
790 800 810 820
pF1KB8 CKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
::::::::::::::::::::::::::::::::::::::::::::
NP_001 CKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
760 770 780 790 800
>>NP_705837 (OMIM: 206200,609862) transmembrane protease (811 aa)
initn: 4926 init1: 4926 opt: 4926 Z-score: 3890.1 bits: 730.7 E(85289): 6.1e-210
Smith-Waterman score: 5558; 97.2% identity (97.3% similar) in 824 aa overlap (1-824:10-811)
10 20 30 40 50
pF1KB8 MPVAEAPQVAGGQGDGGDGEEAEPEGMFKACEDSKRKARGYLRLVPLFVLL
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_705 MLLLFHSKRMPVAEAPQVAGGQGDGGDGEEAEPEGMFKACEDSKRKARGYLRLVPLFVLL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 ALLVLASAGVLLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQDLTRRESSAFRSETAKAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_705 ALLVLASAGVLLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQDLTRRESSAFRSETAKAQK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 MLKELITSTRLGTYYNSSSVYSFGEGPLTCFFWFILQIPEHRRLMLSPEVVQALLVEELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_705 MLKELITSTRLGTYYNSSSVYSFGEGPLTCFFWFILQIPEHRRLMLSPEVVQALLVEELL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 STVNSSAAVPYRAEYEVDPEGLVILEASVKDIAALNSTLGCYRYSYVGQGQVLRLKGPDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_705 STVNSSAAVPYRAEYEVDPEGLVILEASVKDIAALNSTLGCYRYSYVGQGQVLRLKGPDH
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 LASSCLWHLQGPKDLMLKLRLEWTLAECRDRLAMYDVAGPLEKRLITSVYGCSRQEPVVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_705 LASSCLWHLQGPKDLMLKLRLEWTLAECRDRLAMYDVAGPLEKRLITSVYGCSRQEPVVE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 VLASGAIMAVVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQGVLSTPYFPSYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_705 VLASGAIMAVVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQGVLSTPYFPSYY
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 SPQTHCSWHLTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRLCGLRILQPYAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_705 SPQTHCSWHLTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRLCGLRILQPYAE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB8 RIPVVATAGITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVPACDGVKDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_705 RIPVVATAGITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVPACDGVKDC
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB8 PNGLDERNCVCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_705 PNGLDERNCVCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCED
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB8 RSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_705 RSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRH
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB8 ICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_705 ICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYH
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB8 EEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGALRADAV
:::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_705 EEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGG------
670 680 690 700 710
720 730 740 750 760 770
pF1KB8 ALFYGWRNQGSETCCCPISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKKDAC
::::::::::::::::::::::::::::::::::::::::::::
NP_705 ----------------PISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKKDAC
720 730 740 750
780 790 800 810 820
pF1KB8 QGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_705 QGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
760 770 780 790 800 810
>>XP_011528291 (OMIM: 206200,609862) PREDICTED: transmem (680 aa)
initn: 4810 init1: 3959 opt: 3959 Z-score: 3130.2 bits: 589.9 E(85289): 1.3e-167
Smith-Waterman score: 4526; 82.5% identity (82.5% similar) in 824 aa overlap (1-824:1-680)
10 20 30 40 50 60
pF1KB8 MPVAEAPQVAGGQGDGGDGEEAEPEGMFKACEDSKRKARGYLRLVPLFVLLALLVLASAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPVAEAPQVAGGQGDGGDGEEAEPEGMFKACEDSKRKARGYLRLVPLFVLLALLVLASAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VLLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQDLTRRESSAFRSETAKAQKMLKELITST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLLWYFLGYKAEVMVSQVYSGSLRVLNRHFSQDLTRRESSAFRSETAKAQKMLKELITST
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RLGTYYNSSSVYSFGEGPLTCFFWFILQIPEHRRLMLSPEVVQALLVEELLSTVNSSAAV
:::::::::::::::
XP_011 RLGTYYNSSSVYSFG---------------------------------------------
130
190 200 210 220 230 240
pF1KB8 PYRAEYEVDPEGLVILEASVKDIAALNSTLGCYRYSYVGQGQVLRLKGPDHLASSCLWHL
XP_011 ------------------------------------------------------------
250 260 270 280 290 300
pF1KB8 QGPKDLMLKLRLEWTLAECRDRLAMYDVAGPLEKRLITSVYGCSRQEPVVEVLASGAIMA
:::::::::::::::::::::
XP_011 ---------------------------------------VYGCSRQEPVVEVLASGAIMA
140 150
310 320 330 340 350 360
pF1KB8 VVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQGVLSTPYFPSYYSPQTHCSWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQGVLSTPYFPSYYSPQTHCSWH
160 170 180 190 200 210
370 380 390 400 410 420
pF1KB8 LTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRLCGLRILQPYAERIPVVATAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRLCGLRILQPYAERIPVVATAG
220 230 240 250 260 270
430 440 450 460 470 480
pF1KB8 ITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVPACDGVKDCPNGLDERNC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVPACDGVKDCPNGLDERNC
280 290 300 310 320 330
490 500 510 520 530 540
pF1KB8 VCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCRATFQCKEDSTCISLPKVCDGQPDCLNGSDEEQCQEGVPCGTFTFQCEDRSCVKKPNP
340 350 360 370 380 390
550 560 570 580 590 600
pF1KB8 QCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIAD
400 410 420 430 440 450
610 620 630 640 650 660
pF1KB8 RWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDV
460 470 480 490 500 510
670 680 690 700 710 720
pF1KB8 ALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGALRADAVALFYGWRNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGALRADAVALFYGWRNQ
520 530 540 550 560 570
730 740 750 760 770 780
pF1KB8 GSETCCCPISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKKDACQGDSGGPLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSETCCCPISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKKDACQGDSGGPLV
580 590 600 610 620 630
790 800 810 820
pF1KB8 CKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
::::::::::::::::::::::::::::::::::::::::::::
XP_011 CKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
640 650 660 670 680
>>XP_016862358 (OMIM: 257920,600521) PREDICTED: mannan-b (702 aa)
initn: 429 init1: 131 opt: 496 Z-score: 405.3 bits: 85.7 E(85289): 7.8e-16
Smith-Waterman score: 574; 28.0% identity (53.2% similar) in 560 aa overlap (324-821:153-687)
300 310 320 330 340 350
pF1KB8 ASGAIMAVVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQ-GVLSTPYFPSYYS
..:.:. . :: . .. ::...: ::. :
XP_016 EELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECS-DNLFTQRTGVITSPDFPNPYP
130 140 150 160 170 180
360 370 380 390 400 410
pF1KB8 PQTHCSWHLTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRLCGLRILQPY-AE
...: . . . . . : :. ... ..:: :. : ..: :. .:
XP_016 KSSECLYTIELEE-GFMVNLQFEDIFDIEDHPEVPCPYDYIKIK----VGPKVLGPFCGE
190 200 210 220 230
420 430 440 450 460
pF1KB8 RIP---VVATAGITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVP--ACD
. : . . .. : : :. : . : :. : .. :: :. :.: : :
XP_016 KAPEPISTQSHSVLILFHSDNSGENRGWRLSY--RAAGNECP-ELQPPVHGKIEPSQAKY
240 250 260 270 280 290
470 480 490 500 510
pF1KB8 GVKD-----CPNGLDE-RNCVCRATFQ--CKEDSTCISLPKVCDGQPDCLNGSDEEQ--C
:: : .: .. : ::: : .:.: . .: :: .. :.
XP_016 FFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCK-IVDCRAPGELEHGLI
300 310 320 330 340 350
520 530 540 550 560
pF1KB8 QEGVPCGTFTFQCEDRSCVKKPNPQC----DGRPDCRD---------GSDEEHC--DCGL
.. . :.. : . ..: . : : : . : .::
XP_016 TFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQGVWMNKVLGRSLPTCLPECGQ
360 370 380 390 400 410
570 580 590 600
pF1KB8 QG---PS--SRIVGGAVSSEGEWPWQASLQVRG-------RHICGGALIADRWVITAAHC
. :: .::.:: . : .:::: . :. . . .:::.. :..::::
XP_016 PSRSLPSLVKRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHV
420 430 440 450 460 470
610 620 630 640 650 660
pF1KB8 FQEDSMASTVL------WTVFLGKVWQNSR-WPGEVSFKVSRLLLHPYHEEDSHDYDVAL
.. . .::. ::.:: .. : : :. ...:..::: . .....:.::
XP_016 LRSQRRDTTVIPVSKEHVTVYLG--LHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIAL
480 490 500 510 520 530
670 680 690 700 710 720
pF1KB8 LQLDHPVVRSAAVRPVCLPARSHFFEPGLHCW--ITGWGALREGALRADAVALFYGWRNQ
.::..:: . : ::::: : . :. : ..::: . . . .: . ..
XP_016 VQLQEPVPLGPHVMPVCLP-RLEPEGPAPHMLGLVAGWG-ISNPNVTVDEII------SS
540 550 560 570 580
730 740 750 760 770
pF1KB8 GSETCCCPISNALQKVDVQLIPQDLCSEVYR-----YQVTPRMLCAGYRKGKKDACQGDS
:..: .:..:: : . ..:. :. :. :.:: :.:::: .: ::.: :::
XP_016 GTRT----LSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDS
590 600 610 620 630
780 790 800 810 820
pF1KB8 GGPLVC-KALSGRWFLAGLVSWGLG---CGRPNYFGVYTRITGVISWIQQVVT
:: .: :: :: . :::::: : :: . .::::.... ..:. .
XP_016 GGAFVIFDDLSQRWVVQGLVSWG-GPEECGSKQVYGVYTKVSNYVDWVWEQMGLPQSVVE
640 650 660 670 680 690
XP_016 PQVER
700
>>NP_624302 (OMIM: 257920,600521) mannan-binding lectin (728 aa)
initn: 429 init1: 131 opt: 496 Z-score: 405.1 bits: 85.7 E(85289): 8e-16
Smith-Waterman score: 574; 28.0% identity (53.2% similar) in 560 aa overlap (324-821:179-713)
300 310 320 330 340 350
pF1KB8 ASGAIMAVVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQ-GVLSTPYFPSYYS
..:.:. . :: . .. ::...: ::. :
NP_624 EELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECS-DNLFTQRTGVITSPDFPNPYP
150 160 170 180 190 200
360 370 380 390 400 410
pF1KB8 PQTHCSWHLTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRLCGLRILQPY-AE
...: . . . . . : :. ... ..:: :. : ..: :. .:
NP_624 KSSECLYTIELEE-GFMVNLQFEDIFDIEDHPEVPCPYDYIKIK----VGPKVLGPFCGE
210 220 230 240 250 260
420 430 440 450 460
pF1KB8 RIP---VVATAGITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVP--ACD
. : . . .. : : :. : . : :. : .. :: :. :.: : :
NP_624 KAPEPISTQSHSVLILFHSDNSGENRGWRLSY--RAAGNECP-ELQPPVHGKIEPSQAKY
270 280 290 300 310
470 480 490 500 510
pF1KB8 GVKD-----CPNGLDE-RNCVCRATFQ--CKEDSTCISLPKVCDGQPDCLNGSDEEQ--C
:: : .: .. : ::: : .:.: . .: :: .. :.
NP_624 FFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCK-IVDCRAPGELEHGLI
320 330 340 350 360 370
520 530 540 550 560
pF1KB8 QEGVPCGTFTFQCEDRSCVKKPNPQC----DGRPDCRD---------GSDEEHC--DCGL
.. . :.. : . ..: . : : : . : .::
NP_624 TFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQGVWMNKVLGRSLPTCLPECGQ
380 390 400 410 420 430
570 580 590 600
pF1KB8 QG---PS--SRIVGGAVSSEGEWPWQASLQVRG-------RHICGGALIADRWVITAAHC
. :: .::.:: . : .:::: . :. . . .:::.. :..::::
NP_624 PSRSLPSLVKRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHV
440 450 460 470 480 490
610 620 630 640 650 660
pF1KB8 FQEDSMASTVL------WTVFLGKVWQNSR-WPGEVSFKVSRLLLHPYHEEDSHDYDVAL
.. . .::. ::.:: .. : : :. ...:..::: . .....:.::
NP_624 LRSQRRDTTVIPVSKEHVTVYLG--LHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIAL
500 510 520 530 540 550
670 680 690 700 710 720
pF1KB8 LQLDHPVVRSAAVRPVCLPARSHFFEPGLHCW--ITGWGALREGALRADAVALFYGWRNQ
.::..:: . : ::::: : . :. : ..::: . . . .: . ..
NP_624 VQLQEPVPLGPHVMPVCLP-RLEPEGPAPHMLGLVAGWG-ISNPNVTVDEII------SS
560 570 580 590 600
730 740 750 760 770
pF1KB8 GSETCCCPISNALQKVDVQLIPQDLCSEVYR-----YQVTPRMLCAGYRKGKKDACQGDS
:..: .:..:: : . ..:. :. :. :.:: :.:::: .: ::.: :::
NP_624 GTRT----LSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDS
610 620 630 640 650 660
780 790 800 810 820
pF1KB8 GGPLVC-KALSGRWFLAGLVSWGLG---CGRPNYFGVYTRITGVISWIQQVVT
:: .: :: :: . :::::: : :: . .::::.... ..:. .
NP_624 GGAFVIFDDLSQRWVVQGLVSWG-GPEECGSKQVYGVYTKVSNYVDWVWEQMGLPQSVVE
670 680 690 700 710 720
NP_624 PQVER
>>XP_011511291 (OMIM: 257920,600521) PREDICTED: mannan-b (735 aa)
initn: 429 init1: 131 opt: 496 Z-score: 405.0 bits: 85.7 E(85289): 8e-16
Smith-Waterman score: 574; 28.0% identity (53.2% similar) in 560 aa overlap (324-821:186-720)
300 310 320 330 340 350
pF1KB8 ASGAIMAVVWKKGLHSYYDPFVLSVQPVVFQACEVNLTLDNRLDSQ-GVLSTPYFPSYYS
..:.:. . :: . .. ::...: ::. :
XP_011 EELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECS-DNLFTQRTGVITSPDFPNPYP
160 170 180 190 200 210
360 370 380 390 400 410
pF1KB8 PQTHCSWHLTVPSLDYGLALWFDAYALRRQKYDLPCTQGQWTIQNRRLCGLRILQPY-AE
...: . . . . . : :. ... ..:: :. : ..: :. .:
XP_011 KSSECLYTIELEE-GFMVNLQFEDIFDIEDHPEVPCPYDYIKIK----VGPKVLGPFCGE
220 230 240 250 260
420 430 440 450 460
pF1KB8 RIP---VVATAGITINFTSQISLTGPGVRVHYGLYNQSDPCPGEFLCSVNGLCVP--ACD
. : . . .. : : :. : . : :. : .. :: :. :.: : :
XP_011 KAPEPISTQSHSVLILFHSDNSGENRGWRLSY--RAAGNECP-ELQPPVHGKIEPSQAKY
270 280 290 300 310 320
470 480 490 500 510
pF1KB8 GVKD-----CPNGLDE-RNCVCRATFQ--CKEDSTCISLPKVCDGQPDCLNGSDEEQ--C
:: : .: .. : ::: : .:.: . .: :: .. :.
XP_011 FFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCK-IVDCRAPGELEHGLI
330 340 350 360 370 380
520 530 540 550 560
pF1KB8 QEGVPCGTFTFQCEDRSCVKKPNPQC----DGRPDCRD---------GSDEEHC--DCGL
.. . :.. : . ..: . : : : . : .::
XP_011 TFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQGVWMNKVLGRSLPTCLPECGQ
390 400 410 420 430 440
570 580 590 600
pF1KB8 QG---PS--SRIVGGAVSSEGEWPWQASLQVRG-------RHICGGALIADRWVITAAHC
. :: .::.:: . : .:::: . :. . . .:::.. :..::::
XP_011 PSRSLPSLVKRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHV
450 460 470 480 490 500
610 620 630 640 650 660
pF1KB8 FQEDSMASTVL------WTVFLGKVWQNSR-WPGEVSFKVSRLLLHPYHEEDSHDYDVAL
.. . .::. ::.:: .. : : :. ...:..::: . .....:.::
XP_011 LRSQRRDTTVIPVSKEHVTVYLG--LHDVRDKSGAVNSSAARVVLHPDFNIQNYNHDIAL
510 520 530 540 550 560
670 680 690 700 710 720
pF1KB8 LQLDHPVVRSAAVRPVCLPARSHFFEPGLHCW--ITGWGALREGALRADAVALFYGWRNQ
.::..:: . : ::::: : . :. : ..::: . . . .: . ..
XP_011 VQLQEPVPLGPHVMPVCLP-RLEPEGPAPHMLGLVAGWG-ISNPNVTVDEII------SS
570 580 590 600 610
730 740 750 760 770
pF1KB8 GSETCCCPISNALQKVDVQLIPQDLCSEVYR-----YQVTPRMLCAGYRKGKKDACQGDS
:..: .:..:: : . ..:. :. :. :.:: :.:::: .: ::.: :::
XP_011 GTRT----LSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDS
620 630 640 650 660 670
780 790 800 810 820
pF1KB8 GGPLVC-KALSGRWFLAGLVSWGLG---CGRPNYFGVYTRITGVISWIQQVVT
:: .: :: :: . :::::: : :: . .::::.... ..:. .
XP_011 GGAFVIFDDLSQRWVVQGLVSWG-GPEECGSKQVYGVYTKVSNYVDWVWEQMGLPQSVVE
680 690 700 710 720 730
XP_011 PQVER
>>NP_690851 (OMIM: 613797) serine protease 33 precursor (280 aa)
initn: 777 init1: 267 opt: 486 Z-score: 402.1 bits: 83.8 E(85289): 1.2e-15
Smith-Waterman score: 742; 47.0% identity (63.9% similar) in 266 aa overlap (559-824:28-279)
530 540 550 560 570 580
pF1KB8 CEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVR
:: ::::::: . .::::::::.: :
NP_690 MRGVSCLQVLLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHR
10 20 30 40 50
590 600 610 620 630 640
pF1KB8 GRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLH
: :.:::.::: .::.:::::: . .. . . : :: . .: : .: : :.::
NP_690 GAHVCGGSLIAPQWVLTAAHCFPRRALPAE--YRVRLGALRLGSTSPRTLSVPVRRVLLP
60 70 80 90 100 110
650 660 670 680 690 700
pF1KB8 PYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGALRA
: . ::. :.::::: .:: :: :.:::::. . :: : .::::.:: :.
NP_690 PDYSEDGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLP
120 130 140 150 160 170
710 720 730 740 750 760
pF1KB8 DAVALFYGWRNQGSETCCCPISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKK
. : : : .. : ..: .: .. .:: . : : : ::::: .:.:
NP_690 EWRPL-QGVRVPLLDSRTC---DGLYHVGAD-VPQ-----AERI-VLPGSLCAGYPQGHK
180 190 200 210 220
770 780 790 800 810 820
pF1KB8 DACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
:::::::::::.: :: : :.:.:::: ::. :: :::: .. ::: :.
NP_690 DACQGDSGGPLTCLQ-SGSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWIQARVSF
230 240 250 260 270 280
>>XP_011520753 (OMIM: 613797) PREDICTED: serine protease (280 aa)
initn: 777 init1: 267 opt: 486 Z-score: 402.1 bits: 83.8 E(85289): 1.2e-15
Smith-Waterman score: 742; 47.0% identity (63.9% similar) in 266 aa overlap (559-824:28-279)
530 540 550 560 570 580
pF1KB8 CEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVR
:: ::::::: . .::::::::.: :
XP_011 MRGVSCLQVLLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHR
10 20 30 40 50
590 600 610 620 630 640
pF1KB8 GRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLH
: :.:::.::: .::.:::::: . .. . . : :: . .: : .: : :.::
XP_011 GAHVCGGSLIAPQWVLTAAHCFPRRALPAE--YRVRLGALRLGSTSPRTLSVPVRRVLLP
60 70 80 90 100 110
650 660 670 680 690 700
pF1KB8 PYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGALRA
: . ::. :.::::: .:: :: :.:::::. . :: : .::::.:: :.
XP_011 PDYSEDGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLP
120 130 140 150 160 170
710 720 730 740 750 760
pF1KB8 DAVALFYGWRNQGSETCCCPISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKK
. : : : .. : ..: .: .. .:: . : : : ::::: .:.:
XP_011 EWRPL-QGVRVPLLDSRTC---DGLYHVGAD-VPQ-----AERI-VLPGSLCAGYPQGHK
180 190 200 210 220
770 780 790 800 810 820
pF1KB8 DACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
:::::::::::.: :: : :.:.:::: ::. :: :::: .. ::: :.
XP_011 DACQGDSGGPLTCLQ-SGSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWIQARVSF
230 240 250 260 270 280
>>XP_011520754 (OMIM: 613797) PREDICTED: serine protease (280 aa)
initn: 777 init1: 267 opt: 486 Z-score: 402.1 bits: 83.8 E(85289): 1.2e-15
Smith-Waterman score: 742; 47.0% identity (63.9% similar) in 266 aa overlap (559-824:28-279)
530 540 550 560 570 580
pF1KB8 CEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVR
:: ::::::: . .::::::::.: :
XP_011 MRGVSCLQVLLLLVLGAAGTQGRKSAACGQPRMSSRIVGGRDGRDGEWPWQASIQHR
10 20 30 40 50
590 600 610 620 630 640
pF1KB8 GRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLH
: :.:::.::: .::.:::::: . .. . . : :: . .: : .: : :.::
XP_011 GAHVCGGSLIAPQWVLTAAHCFPRRALPAE--YRVRLGALRLGSTSPRTLSVPVRRVLLP
60 70 80 90 100 110
650 660 670 680 690 700
pF1KB8 PYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGALRA
: . ::. :.::::: .:: :: :.:::::. . :: : .::::.:: :.
XP_011 PDYSEDGARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLP
120 130 140 150 160 170
710 720 730 740 750 760
pF1KB8 DAVALFYGWRNQGSETCCCPISNALQKVDVQLIPQDLCSEVYRYQVTPRMLCAGYRKGKK
. : : : .. : ..: .: .. .:: . : : : ::::: .:.:
XP_011 EWRPL-QGVRVPLLDSRTC---DGLYHVGAD-VPQ-----AERI-VLPGSLCAGYPQGHK
180 190 200 210 220
770 780 790 800 810 820
pF1KB8 DACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
:::::::::::.: :: : :.:.:::: ::. :: :::: .. ::: :.
XP_011 DACQGDSGGPLTCLQ-SGSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWIQARVSF
230 240 250 260 270 280
824 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 22:17:10 2016 done: Sat Nov 5 22:17:12 2016
Total Scan time: 11.650 Total Display time: 0.190
Function used was FASTA [36.3.4 Apr, 2011]