FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8648, 340 aa 1>>>pF1KB8648 340 - 340 aa - 340 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8490+/-0.000363; mu= 18.4766+/- 0.023 mean_var=60.2674+/-11.848, 0's: 0 Z-trim(111.6): 70 B-trim: 447 in 2/54 Lambda= 0.165209 statistics sampled from 20235 (20306) to 20235 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.609), E-opt: 0.2 (0.238), width: 16 Scan time: 7.830 The best scores are: opt bits E(85289) NP_008999 (OMIM: 602721) meiotic recombination pro ( 340) 2192 531.0 1.4e-150 XP_011528137 (OMIM: 602721) PREDICTED: meiotic rec ( 362) 2046 496.3 4.3e-140 XP_011528136 (OMIM: 602721) PREDICTED: meiotic rec ( 362) 2046 496.3 4.3e-140 XP_011520160 (OMIM: 114480,179617,614508) PREDICTE ( 339) 1108 272.7 8.2e-73 NP_002866 (OMIM: 114480,179617,614508) DNA repair ( 339) 1108 272.7 8.2e-73 XP_006720689 (OMIM: 114480,179617,614508) PREDICTE ( 339) 1108 272.7 8.2e-73 XP_011520161 (OMIM: 114480,179617,614508) PREDICTE ( 339) 1108 272.7 8.2e-73 XP_011520159 (OMIM: 114480,179617,614508) PREDICTE ( 339) 1108 272.7 8.2e-73 XP_011520162 (OMIM: 114480,179617,614508) PREDICTE ( 339) 1108 272.7 8.2e-73 NP_597994 (OMIM: 114480,179617,614508) DNA repair ( 340) 948 234.5 2.5e-61 NP_001157741 (OMIM: 114480,179617,614508) DNA repa ( 340) 948 234.5 2.5e-61 XP_016884031 (OMIM: 602721) PREDICTED: meiotic rec ( 271) 929 229.9 4.7e-60 XP_006724175 (OMIM: 602721) PREDICTED: meiotic rec ( 285) 919 227.6 2.6e-59 NP_001265137 (OMIM: 602721) meiotic recombination ( 285) 919 227.6 2.6e-59 XP_011528139 (OMIM: 602721) PREDICTED: meiotic rec ( 307) 902 223.5 4.5e-58 XP_011528140 (OMIM: 602721) PREDICTED: meiotic rec ( 293) 816 203.0 6.5e-52 XP_011520164 (OMIM: 114480,179617,614508) PREDICTE ( 215) 787 196.0 6.1e-50 NP_001157742 (OMIM: 114480,179617,614508) DNA repa ( 280) 756 188.7 1.3e-47 XP_011520163 (OMIM: 114480,179617,614508) PREDICTE ( 280) 756 188.7 1.3e-47 NP_001308738 (OMIM: 602948) DNA repair protein RAD ( 347) 314 83.4 7.7e-16 NP_001308747 (OMIM: 602948) DNA repair protein RAD ( 347) 314 83.4 7.7e-16 NP_001308739 (OMIM: 602948) DNA repair protein RAD ( 347) 314 83.4 7.7e-16 NP_001308748 (OMIM: 602948) DNA repair protein RAD ( 348) 314 83.4 7.8e-16 NP_002868 (OMIM: 602948) DNA repair protein RAD51 ( 350) 314 83.4 7.8e-16 NP_598194 (OMIM: 602948) DNA repair protein RAD51 ( 350) 314 83.4 7.8e-16 NP_001308743 (OMIM: 602948) DNA repair protein RAD ( 351) 314 83.4 7.8e-16 NP_001308741 (OMIM: 602948) DNA repair protein RAD ( 351) 314 83.4 7.8e-16 NP_598193 (OMIM: 602948) DNA repair protein RAD51 ( 384) 314 83.5 8.4e-16 NP_001308750 (OMIM: 602948) DNA repair protein RAD ( 425) 314 83.5 9.1e-16 NP_001308744 (OMIM: 602948) DNA repair protein RAD ( 332) 307 81.7 2.4e-15 XP_011535352 (OMIM: 602948) PREDICTED: DNA repair ( 274) 266 71.9 1.8e-12 XP_011535353 (OMIM: 602948) PREDICTED: DNA repair ( 258) 264 71.4 2.4e-12 XP_016877034 (OMIM: 602948) PREDICTED: DNA repair ( 500) 264 71.6 4e-12 NP_001308746 (OMIM: 602948) DNA repair protein RAD ( 231) 222 61.4 2.2e-09 XP_016877036 (OMIM: 602948) PREDICTED: DNA repair ( 306) 222 61.5 2.8e-09 XP_006722065 (OMIM: 189960,602774,613390,613399) P ( 342) 193 54.6 3.7e-07 NP_005423 (OMIM: 114480,600675,613972) DNA repair ( 346) 193 54.6 3.7e-07 NP_001093589 (OMIM: 114480,600675,613972) DNA repa ( 346) 193 54.6 3.7e-07 XP_011535440 (OMIM: 114480,600675,613972) PREDICTE ( 346) 193 54.6 3.7e-07 XP_005268103 (OMIM: 114480,600675,613972) PREDICTE ( 346) 193 54.6 3.7e-07 NP_001093588 (OMIM: 114480,600675,613972) DNA repa ( 346) 193 54.6 3.7e-07 NP_478123 (OMIM: 189960,602774,613390,613399) DNA ( 376) 193 54.6 4e-07 XP_006722064 (OMIM: 189960,602774,613390,613399) P ( 377) 193 54.6 4e-07 NP_002869 (OMIM: 602954,614291) DNA repair protein ( 328) 184 52.4 1.6e-06 NP_001136043 (OMIM: 602954,614291) DNA repair prot ( 348) 177 50.8 5.2e-06 XP_016877035 (OMIM: 602948) PREDICTED: DNA repair ( 324) 160 46.7 8.2e-05 NP_005422 (OMIM: 600375) DNA repair protein XRCC2 ( 280) 152 44.8 0.00027 XP_016880408 (OMIM: 189960,602774,613390,613399) P ( 225) 139 41.6 0.002 XP_016880403 (OMIM: 189960,602774,613390,613399) P ( 259) 139 41.6 0.0022 XP_016880404 (OMIM: 189960,602774,613390,613399) P ( 259) 139 41.6 0.0022 >>NP_008999 (OMIM: 602721) meiotic recombination protein (340 aa) initn: 2192 init1: 2192 opt: 2192 Z-score: 2824.6 bits: 531.0 E(85289): 1.4e-150 Smith-Waterman score: 2192; 100.0% identity (100.0% similar) in 340 aa overlap (1-340:1-340) 10 20 30 40 50 60 pF1KB8 MKEDQVVAEEPGFQDEEESLFQDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 MKEDQVVAEEPGFQDEEESLFQDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRALC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NVKGLSEAKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 NVKGLSEAKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 ITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 ITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNVD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 HDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 HDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 ERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_008 ERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTR 250 260 270 280 290 300 310 320 330 340 pF1KB8 ISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE :::::::::::::::::::::::::::::::::::::::: NP_008 ISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE 310 320 330 340 >>XP_011528137 (OMIM: 602721) PREDICTED: meiotic recombi (362 aa) initn: 2043 init1: 2043 opt: 2046 Z-score: 2636.1 bits: 496.3 E(85289): 4.3e-140 Smith-Waterman score: 2046; 97.6% identity (98.5% similar) in 327 aa overlap (1-327:1-327) 10 20 30 40 50 60 pF1KB8 MKEDQVVAEEPGFQDEEESLFQDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKEDQVVAEEPGFQDEEESLFQDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRALC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NVKGLSEAKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVKGLSEAKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 ITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNVD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 HDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 ERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTR 250 260 270 280 290 300 310 320 330 340 pF1KB8 ISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE ::::::::::::::::: :..:. XP_011 ISLRKGRGELRIAKIYDRLSEREQKASVKTIKDPEEDTDTWSGGTTHTGACWGSAEGEHR 310 320 330 340 350 360 >>XP_011528136 (OMIM: 602721) PREDICTED: meiotic recombi (362 aa) initn: 2043 init1: 2043 opt: 2046 Z-score: 2636.1 bits: 496.3 E(85289): 4.3e-140 Smith-Waterman score: 2046; 97.6% identity (98.5% similar) in 327 aa overlap (1-327:1-327) 10 20 30 40 50 60 pF1KB8 MKEDQVVAEEPGFQDEEESLFQDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRALC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKEDQVVAEEPGFQDEEESLFQDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRALC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NVKGLSEAKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVKGLSEAKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESMA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 ITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNVD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 HDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGELA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 ERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERQQKLAQMLSRLQKISEEYNVAVFVTNQMTADPGATMTFQADPKKPIGGHILAHASTTR 250 260 270 280 290 300 310 320 330 340 pF1KB8 ISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE ::::::::::::::::: :..:. XP_011 ISLRKGRGELRIAKIYDRLSEREQKASVKTIKDPEEDTDTWSGGTTHTGACWGSAEGEHR 310 320 330 340 350 360 >>XP_011520160 (OMIM: 114480,179617,614508) PREDICTED: D (339 aa) initn: 1161 init1: 615 opt: 1108 Z-score: 1428.2 bits: 272.7 E(85289): 8.2e-73 Smith-Waterman score: 1108; 55.0% identity (79.5% similar) in 327 aa overlap (16-340:16-339) 10 20 30 40 50 pF1KB8 MKEDQVVAEEPGFQDEEESLF-QDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRAL ::::. : :. :.. :::. :.:::. .:. :.... .. .. : XP_011 MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKEL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 CNVKGLSEAKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESM :.::.::::.::: : ::. :: :: :. ..:. ...:::::.:.:::: ::::. XP_011 INIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 AITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNV .::: ::::::::::. ::: :: ::: : :: ..::::.::::.:: .:.:... XP_011 SITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 DHDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGEL . . ::::: ::::....:: .:: : :. . :. . :::.:: ::.:.:.:::::: XP_011 SGSDVLDNVAYARAFNTDHQTQLL-YQASAMMVESR-YALLIVDSATALYRTDYSGRGEL 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 AERQQKLAQMLSRLQKISEEYNVAVFVTNQMTAD-PGATMTFQADPKKPIGGHILAHAST . ::..::..: : ....:..::: .:::..:. ::.: : :::::::::.:.::::: XP_011 SARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAM-FAADPKKPIGGNIIAHAST 240 250 260 270 280 290 300 310 320 330 340 pF1KB8 TRISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE ::. ::::::: :: :::::: .:: :: :::.: :.::::. XP_011 TRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 300 310 320 330 >>NP_002866 (OMIM: 114480,179617,614508) DNA repair prot (339 aa) initn: 1161 init1: 615 opt: 1108 Z-score: 1428.2 bits: 272.7 E(85289): 8.2e-73 Smith-Waterman score: 1108; 55.0% identity (79.5% similar) in 327 aa overlap (16-340:16-339) 10 20 30 40 50 pF1KB8 MKEDQVVAEEPGFQDEEESLF-QDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRAL ::::. : :. :.. :::. :.:::. .:. :.... .. .. : NP_002 MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKEL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 CNVKGLSEAKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESM :.::.::::.::: : ::. :: :: :. ..:. ...:::::.:.:::: ::::. NP_002 INIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 AITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNV .::: ::::::::::. ::: :: ::: : :: ..::::.::::.:: .:.:... NP_002 SITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 DHDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGEL . . ::::: ::::....:: .:: : :. . :. . :::.:: ::.:.:.:::::: NP_002 SGSDVLDNVAYARAFNTDHQTQLL-YQASAMMVESR-YALLIVDSATALYRTDYSGRGEL 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 AERQQKLAQMLSRLQKISEEYNVAVFVTNQMTAD-PGATMTFQADPKKPIGGHILAHAST . ::..::..: : ....:..::: .:::..:. ::.: : :::::::::.:.::::: NP_002 SARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAM-FAADPKKPIGGNIIAHAST 240 250 260 270 280 290 300 310 320 330 340 pF1KB8 TRISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE ::. ::::::: :: :::::: .:: :: :::.: :.::::. NP_002 TRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 300 310 320 330 >>XP_006720689 (OMIM: 114480,179617,614508) PREDICTED: D (339 aa) initn: 1161 init1: 615 opt: 1108 Z-score: 1428.2 bits: 272.7 E(85289): 8.2e-73 Smith-Waterman score: 1108; 55.0% identity (79.5% similar) in 327 aa overlap (16-340:16-339) 10 20 30 40 50 pF1KB8 MKEDQVVAEEPGFQDEEESLF-QDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRAL ::::. : :. :.. :::. :.:::. .:. :.... .. .. : XP_006 MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKEL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 CNVKGLSEAKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESM :.::.::::.::: : ::. :: :: :. ..:. ...:::::.:.:::: ::::. XP_006 INIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 AITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNV .::: ::::::::::. ::: :: ::: : :: ..::::.::::.:: .:.:... XP_006 SITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 DHDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGEL . . ::::: ::::....:: .:: : :. . :. . :::.:: ::.:.:.:::::: XP_006 SGSDVLDNVAYARAFNTDHQTQLL-YQASAMMVESR-YALLIVDSATALYRTDYSGRGEL 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 AERQQKLAQMLSRLQKISEEYNVAVFVTNQMTAD-PGATMTFQADPKKPIGGHILAHAST . ::..::..: : ....:..::: .:::..:. ::.: : :::::::::.:.::::: XP_006 SARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAM-FAADPKKPIGGNIIAHAST 240 250 260 270 280 290 300 310 320 330 340 pF1KB8 TRISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE ::. ::::::: :: :::::: .:: :: :::.: :.::::. XP_006 TRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 300 310 320 330 >>XP_011520161 (OMIM: 114480,179617,614508) PREDICTED: D (339 aa) initn: 1161 init1: 615 opt: 1108 Z-score: 1428.2 bits: 272.7 E(85289): 8.2e-73 Smith-Waterman score: 1108; 55.0% identity (79.5% similar) in 327 aa overlap (16-340:16-339) 10 20 30 40 50 pF1KB8 MKEDQVVAEEPGFQDEEESLF-QDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRAL ::::. : :. :.. :::. :.:::. .:. :.... .. .. : XP_011 MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKEL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 CNVKGLSEAKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESM :.::.::::.::: : ::. :: :: :. ..:. ...:::::.:.:::: ::::. XP_011 INIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 AITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNV .::: ::::::::::. ::: :: ::: : :: ..::::.::::.:: .:.:... XP_011 SITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 DHDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGEL . . ::::: ::::....:: .:: : :. . :. . :::.:: ::.:.:.:::::: XP_011 SGSDVLDNVAYARAFNTDHQTQLL-YQASAMMVESR-YALLIVDSATALYRTDYSGRGEL 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 AERQQKLAQMLSRLQKISEEYNVAVFVTNQMTAD-PGATMTFQADPKKPIGGHILAHAST . ::..::..: : ....:..::: .:::..:. ::.: : :::::::::.:.::::: XP_011 SARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAM-FAADPKKPIGGNIIAHAST 240 250 260 270 280 290 300 310 320 330 340 pF1KB8 TRISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE ::. ::::::: :: :::::: .:: :: :::.: :.::::. XP_011 TRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 300 310 320 330 >>XP_011520159 (OMIM: 114480,179617,614508) PREDICTED: D (339 aa) initn: 1161 init1: 615 opt: 1108 Z-score: 1428.2 bits: 272.7 E(85289): 8.2e-73 Smith-Waterman score: 1108; 55.0% identity (79.5% similar) in 327 aa overlap (16-340:16-339) 10 20 30 40 50 pF1KB8 MKEDQVVAEEPGFQDEEESLF-QDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRAL ::::. : :. :.. :::. :.:::. .:. :.... .. .. : XP_011 MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKEL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 CNVKGLSEAKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESM :.::.::::.::: : ::. :: :: :. ..:. ...:::::.:.:::: ::::. XP_011 INIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 AITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNV .::: ::::::::::. ::: :: ::: : :: ..::::.::::.:: .:.:... XP_011 SITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 DHDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGEL . . ::::: ::::....:: .:: : :. . :. . :::.:: ::.:.:.:::::: XP_011 SGSDVLDNVAYARAFNTDHQTQLL-YQASAMMVESR-YALLIVDSATALYRTDYSGRGEL 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 AERQQKLAQMLSRLQKISEEYNVAVFVTNQMTAD-PGATMTFQADPKKPIGGHILAHAST . ::..::..: : ....:..::: .:::..:. ::.: : :::::::::.:.::::: XP_011 SARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAM-FAADPKKPIGGNIIAHAST 240 250 260 270 280 290 300 310 320 330 340 pF1KB8 TRISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE ::. ::::::: :: :::::: .:: :: :::.: :.::::. XP_011 TRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 300 310 320 330 >>XP_011520162 (OMIM: 114480,179617,614508) PREDICTED: D (339 aa) initn: 1161 init1: 615 opt: 1108 Z-score: 1428.2 bits: 272.7 E(85289): 8.2e-73 Smith-Waterman score: 1108; 55.0% identity (79.5% similar) in 327 aa overlap (16-340:16-339) 10 20 30 40 50 pF1KB8 MKEDQVVAEEPGFQDEEESLF-QDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRAL ::::. : :. :.. :::. :.:::. .:. :.... .. .. : XP_011 MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKEL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 CNVKGLSEAKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHITTGSQEFDKLLGGGIESM :.::.::::.::: : ::. :: :: :. ..:. ...:::::.:.:::: ::::. XP_011 INIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETG 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 AITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLRDIADRFNV .::: ::::::::::. ::: :: ::: : :: ..::::.::::.:: .:.:... XP_011 SITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 DHDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRVDFSGRGEL . . ::::: ::::....:: .:: : :. . :. . :::.:: ::.:.:.:::::: XP_011 SGSDVLDNVAYARAFNTDHQTQLL-YQASAMMVESR-YALLIVDSATALYRTDYSGRGEL 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 AERQQKLAQMLSRLQKISEEYNVAVFVTNQMTAD-PGATMTFQADPKKPIGGHILAHAST . ::..::..: : ....:..::: .:::..:. ::.: : :::::::::.:.::::: XP_011 SARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAM-FAADPKKPIGGNIIAHAST 240 250 260 270 280 290 300 310 320 330 340 pF1KB8 TRISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE ::. ::::::: :: :::::: .:: :: :::.: :.::::. XP_011 TRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 300 310 320 330 >>NP_597994 (OMIM: 114480,179617,614508) DNA repair prot (340 aa) initn: 1033 init1: 497 opt: 948 Z-score: 1222.1 bits: 234.5 E(85289): 2.5e-61 Smith-Waterman score: 948; 50.1% identity (75.2% similar) in 335 aa overlap (16-340:16-340) 10 20 30 40 50 pF1KB8 MKEDQVVAEEPGFQDEEESLF-QDIDLLQKHGINVADIKKLKSVGICTIKGIQMTTRRAL ::::. : :. :.. :::. :.:::. .:. :.... .. .. : NP_597 MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKEL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 CNVKGLSEAKVDKIKEAANKLIEPGFLTAFEYSEKRKMVFHIT--TGSQEF----DKLLG :.::.::::.::: : : .. .: .. .:. .::.. ....: NP_597 INIKGISEAKADKI------LTESRSVARLE-CNSVILVYCTLRLSGSSDSPASASRVVG 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 --GGIESMAITEAFGEFRTGKTQLSHTLCVTAQLPGAGGYPGGKIIFIDTENTFRPDRLR ::::. .::: ::::::::::. ::: :: ::: : :: ..::::.::::.:: NP_597 TTGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLL 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 DIADRFNVDHDAVLDNVLYARAYTSEHQMELLDYVAAKFHEEAGIFKLLIIDSIMALFRV .:.:.... . ::::: ::::....:: .:: : :. . :. . :::.:: ::.:. NP_597 AVAERYGLSGSDVLDNVAYARAFNTDHQTQLL-YQASAMMVESR-YALLIVDSATALYRT 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 DFSGRGELAERQQKLAQMLSRLQKISEEYNVAVFVTNQMTAD-PGATMTFQADPKKPIGG :.::::::. ::..::..: : ....:..::: .:::..:. ::.: : ::::::::: NP_597 DYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAM-FAADPKKPIGG 240 250 260 270 280 290 300 310 320 330 340 pF1KB8 HILAHASTTRISLRKGRGELRIAKIYDSPEMPENEATFAITAGGIGDAKE .:.:::::::. ::::::: :: :::::: .:: :: :::.: :.::::. NP_597 NIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 300 310 320 330 340 340 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 21:50:54 2016 done: Sat Nov 5 21:50:56 2016 Total Scan time: 7.830 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]